Robert Saddawi-konefka

Title(s)Resident Physician, Otolaryngology
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
ORCID ORCID Icon0000-0002-9936-1695 Additional info
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The XCL1-XCR1 axis supports intestinal tissue residency and antitumor immunity. J Exp Med. 2025 Mar 03; 222(2). Ferry A, Mempel KM, Monell A, Reina-Campos M, Scharping NE, Heeg M, Takehara KK, Schokrpur S, Kuo N, Saddawi-Konefka R, Gutkind JS, Goldrath AW. PMID: 39841133; PMCID: PMC11753173.
      View in: PubMed   Mentions:
    2. Let it be: Preserving tumor-draining lymph nodes in the era of immuno-oncology. Cancer Cell. 2024 Jun 10; 42(6):930-933. Saddawi-Konefka R, Schokrpur S, Gutkind JS. PMID: 38861928.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    3. CHMP2A regulates broad immune cell-mediated antitumor activity in an immunocompetent in vivo head and neck squamous cell carcinoma model. J Immunother Cancer. 2024 May 03; 12(5). Yun J, Saddawi-Konefka R, Goldenson B, Al-Msari R, Bernareggi D, Thangaraj JL, Tang S, Patel SH, Luna SM, Gutkind JS, Kaufman D. PMID: 38702144; PMCID: PMC11086353.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    4. High-throughput chemogenetic drug screening reveals PKC-RhoA/PKN as a targetable signaling vulnerability in GNAQ-driven uveal melanoma. Cell Rep Med. 2023 11 21; 4(11):101244. Arang N, Lubrano S, Ceribelli M, Rigiracciolo DC, Saddawi-Konefka R, Faraji F, Ramirez SI, Kim D, Tosto FA, Stevenson E, Zhou Y, Wang Z, Bogomolovas J, Molinolo AA, Swaney DL, Krogan NJ, Yang J, Coma S, Pachter JA, Aplin AE, Alessi DR, Thomas CJ, Gutkind JS. PMID: 37858338; PMCID: PMC10694608.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    5. Simulation-based workshop for emergency preparedness in otolaryngology. Laryngoscope Investig Otolaryngol. 2023 Oct; 8(5):1159-1168. La Monte OA, Lee JH, Soliman SI, Saddawi-Konefka R, Harris JP, Coffey CS, Orosco RK, Watson D, Holliday MA, Faraji F, Hom DB. PMID: 37899850; PMCID: PMC10601586.
      View in: PubMed   Mentions: 1  
    6. The GPCR-Gαs-PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure. Nat Immunol. 2023 08; 24(8):1318-1330. Wu VH, Yung BS, Faraji F, Saddawi-Konefka R, Wang Z, Wenzel AT, Song MJ, Pagadala MS, Clubb LM, Chiou J, Sinha S, Matic M, Raimondi F, Hoang TS, Berdeaux R, Vignali DAA, Iglesias-Bartolome R, Carter H, Ruppin E, Mesirov JP, Gutkind JS. PMID: 37308665; PMCID: PMC10735169.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    7. HER2 and HER3 as Therapeutic Targets in Head and Neck Cancer. Cancer J. 2022 Sep-Oct 01; 28(5):339-345. Saddawi-Konefka R, Schokrpur S, Lui AJ, Gutkind JS. PMID: 36165721; PMCID: PMC9523502.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    8. Lymphatic-preserving treatment sequencing with immune checkpoint inhibition unleashes cDC1-dependent antitumor immunity in HNSCC. Nat Commun. 2022 07 25; 13(1):4298. Saddawi-Konefka R, O'Farrell A, Faraji F, Clubb L, Allevato MM, Jensen SM, Yung BS, Wang Z, Wu VH, Anang NA, Msari RA, Schokrpur S, Pietryga IF, Molinolo AA, Mesirov JP, Simon AB, Fox BA, Bui JD, Sharabi A, Cohen EEW, Califano JA, Gutkind JS. PMID: 35879302; PMCID: PMC9314425.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    9. Microneedle-mediated Intratumoral Delivery of Anti-CTLA-4 Promotes cDC1-dependent Eradication of Oral Squamous Cell Carcinoma with Limited irAEs. Mol Cancer Ther. 2022 04 01; 21(4):616-624. Gilardi M, Saddawi-Konefka R, Wu VH, Lopez-Ramirez MA, Wang Z, Soto F, Ramms DJ, Proietto M, Mikulski Z, Miki H, Sharabi A, Kupor D, Rueda R, Hollern DP, Wang J, Gutkind JS. PMID: 35086958; PMCID: PMC8983493.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    10. Defining the Role of Immunotherapy in the Curative Treatment of Locoregionally Advanced Head and Neck Cancer: Promises, Challenges, and Opportunities. Front Oncol. 2021; 11:738626. Saddawi-Konefka R, Simon AB, Sumner W, Sharabi A, Mell LK, Cohen EEW. PMID: 34621678; PMCID: PMC8490924.
      View in: PubMed   Mentions: 5  
    11. Correction: Synthetic Lethal Screens Reveal Cotargeting FAK and MEK as a Multimodal Precision Therapy for GNAQ-Driven Uveal Melanoma. Clin Cancer Res. 2021 Aug 15; 27(16):4664. Paradis JS, Acosta M, Saddawi-Konefka R, Kishore A, Lubrano S, Gomes F, Arang N, Tiago M, Coma S, Wu X, Ford K, Day CP, Merlino G, Mali P, Pachter JA, Sato T, Aplin AE, Gutkind JS. PMID: 34389658.
      View in: PubMed   Mentions: 1     Fields:    
    12. Disruption of the HER3-PI3K-mTOR oncogenic signaling axis and PD-1 blockade as a multimodal precision immunotherapy in head and neck cancer. Nat Commun. 2021 04 22; 12(1):2383. Wang Z, Goto Y, Allevato MM, Wu VH, Saddawi-Konefka R, Gilardi M, Alvarado D, Yung BS, O'Farrell A, Molinolo AA, Duvvuri U, Grandis JR, Califano JA, Cohen EEW, Gutkind JS. PMID: 33888713; PMCID: PMC8062674.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    13. Synthetic Lethal Screens Reveal Cotargeting FAK and MEK as a Multimodal Precision Therapy for GNAQ-Driven Uveal Melanoma. Clin Cancer Res. 2021 06 01; 27(11):3190-3200. Paradis JS, Acosta M, Saddawi-Konefka R, Kishore A, Gomes F, Arang N, Tiago M, Coma S, Lubrano S, Wu X, Ford K, Day CP, Merlino G, Mali P, Pachter JA, Sato T, Aplin AE, Gutkind JS. PMID: 33568347; PMCID: PMC8895627.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    14. Immunotherapy in sinonasal melanoma: treatment patterns and outcomes compared to cutaneous melanoma. Int Forum Allergy Rhinol. 2020 09; 10(9):1087-1095. Klebaner D, Saddawi-Konefka R, Finegersh A, Yan CH, Califano JA, London NR, Deconde AS, Faraji F. PMID: 32623838.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    15. Meta-analysis of risk of occult lymph node metastasis in the irradiated, clinically N0 neck. Head Neck. 2020 09; 42(9):2355-2363. Finegersh A, Moss WJ, Saddawi-Konefka R, Faraji F, Coffey CS, Califano JA, Brumund KT, Orosco RK. PMID: 32432819.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    16. The role of 3D printing in pediatric airway obstruction: A systematic review. Int J Pediatr Otorhinolaryngol. 2020 May; 132:109923. Stramiello JA, Saddawi-Konefka R, Ryan J, Brigger MT. PMID: 32035351.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    17. Transient Abducens Nerve Palsy After Sphenopalatine Block Following Endoscopic Sinus Surgery. JAMA Otolaryngol Head Neck Surg. 2019 Sep 01; 145(9):871-873. Saddawi-Konefka R, Jafari A, Bracken D, Deconde A. PMID: 31343691.
      View in: PubMed   Mentions: 1     Fields:    
    18. Nonsurgical Treatment of Keloids and Hypertrophic Scars. Facial Plast Surg. 2019 Jun; 35(3):260-266. Saddawi-Konefka R, Watson D. PMID: 31189199.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. Perioperative Risk Factors Associated With Morbidity and Mortality Following Pediatric Inpatient Sinus Surgery. Ann Otol Rhinol Laryngol. 2019 Jan; 128(1):13-21. Burton BN, Gilani S, Desai M, Saddawi-Konefka R, Willies-Jacobo L, Gabriel RA. PMID: 30328698.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    20. A Lot to Choke on: Case of Adult Epiglottitis with Concurrent Peritonsillar Abscess in a Patient with a Sore Throat. J Emerg Med. 2018 Dec; 55(6):841-844. Parthasarathy V, Snyder B, Saddawi-Konefka R. PMID: 30342860.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    21. Interleukin-17D and Nrf2 mediate initial innate immune cell recruitment and restrict MCMV infection. Sci Rep. 2018 09 12; 8(1):13670. Seelige R, Saddawi-Konefka R, Adams NM, Picarda G, Sun JC, Benedict CA, Bui JD. PMID: 30209334; PMCID: PMC6135835.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    22. Inverted schneiderian papilloma of the supraglottis: Case report. Laryngoscope. 2017 12; 127(12):2830-2832. Saddawi-Konefka R, Hariri N, Shabaik A, Weissbrod PA. PMID: 28699194.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    23. Nrf2 Induces IL-17D to Mediate Tumor and Virus Surveillance. Cell Rep. 2016 08 30; 16(9):2348-58. Saddawi-Konefka R, Seelige R, Gross ET, Levy E, Searles SC, Washington A, Santosa EK, Liu B, O'Sullivan TE, Harismendy O, Bui JD. PMID: 27545889; PMCID: PMC5007173.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    24. Tumor-expressed IL-17D recruits NK cells to reject tumors. Oncoimmunology. 2014 Dec; 3(12):e954853. Saddawi-Konefka R, O'Sullivan T, Gross ET, Washington A, Bui JD. PMID: 25964859; PMCID: PMC4353093.
      View in: PubMed   Mentions: 17     Fields:    
    25. Interleukin-17D mediates tumor rejection through recruitment of natural killer cells. Cell Rep. 2014 May 22; 7(4):989-98. O'Sullivan T, Saddawi-Konefka R, Gross E, Tran M, Mayfield SP, Ikeda H, Bui JD. PMID: 24794441; PMCID: PMC4084720.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    26. Cancer immunoediting by the innate immune system in the absence of adaptive immunity. J Exp Med. 2012 Sep 24; 209(10):1869-82. O'Sullivan T, Saddawi-Konefka R, Vermi W, Koebel CM, Arthur C, White JM, Uppaluri R, Andrews DM, Ngiow SF, Teng MW, Smyth MJ, Schreiber RD, Bui JD. PMID: 22927549; PMCID: PMC3457735.
      View in: PubMed   Mentions: 189     Fields:    Translation:AnimalsCells
    27. Chronic viral infection and primary central nervous system malignancy. J Neuroimmune Pharmacol. 2010 Sep; 5(3):387-403. Saddawi-Konefka R, Crawford JR. PMID: 20387126; PMCID: PMC2914282.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
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