Herve Tiriac

Title(s)	Assistant Researcher, Surgery
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
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Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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MICAL2 Is a Super Enhancer Associated Gene that Promotes Pancreatic Cancer Growth and Metastasis. bioRxiv. 2024 Jun 30. Garg B, Khan S, Babu DS, Mose E, Gulay K, Sharma S, Sood D, Wenzel AT, Martsinkovskiy A, Patel J, Jaquish D, Lambies G, D'Ippolito A, Austgen K, Johnston B, Orlando D, Jang GH, Gallinger S, Goodfellow E, Brodt P, Commisso C, Tamayo P, Mesirov JP, Tiriac H, Lowy AM. PMID: 38979336; PMCID: PMC11230455.

View in: PubMed Mentions:
ZBTB11 Depletion Targets Metabolic Vulnerabilities in K-Ras Inhibitor Resistant PDAC. bioRxiv. 2024 May 21. Tran NL, Jiang J, Ma M, Gadbois GE, Gulay KCM, Verano A, Zhou H, Huang CT, Scott DA, Bang AG, Tiriac H, Lowy AM, Wang ES, Ferguson FM. PMID: 38826238; PMCID: PMC11142081.

View in: PubMed Mentions:
The novel drug candidate S2/IAPinh improves survival in models of pancreatic and ovarian cancer. Sci Rep. 2024 03 16; 14(1):6373. Hagi T, Vangveravong S, Takchi R, Gong Q, Goedegebuure SP, Tiriac H, Van Tine BA, Powell MA, Hawkins WG, Spitzer D. PMID: 38493257; PMCID: PMC10944456.

View in: PubMed Mentions: Fields:
Sci Science
Translation:Humans Animals Cells
The effect of extracellular matrix on the precision medicine utility of pancreatic cancer patient-derived organoids. JCI Insight. 2024 Jan 09; 9(1). Lumibao JC, Okhovat SR, Peck KL, Lin X, Lande K, Yomtoubian S, Ng I, Tiriac H, Lowy AM, Zou J, Engle DD. PMID: 38051586; PMCID: PMC10906458.

View in: PubMed Mentions: 2 Fields:
Med Medicine (General)
Translation:Humans Animals Cells
Engrailed-1 Promotes Pancreatic Cancer Metastasis. Adv Sci (Weinh). 2024 02; 11(6):e2308537. Xu J, Roe JS, Lee E, Tonelli C, Ji KY, Younis OW, Somervile TDD, Yao M, Milazzo JP, Tiriac H, Kolarzyk AM, Lee E, Grem JL, Lazenby AJ, Grunkemeyer JA, Hollingsworth MA, Grandgenett PM, Borowsky AD, Park Y, Vakoc CR, Tuveson DA, Hwang CI. PMID: 38110836; PMCID: PMC10853725.

View in: PubMed Mentions: 1 Fields:
Bio Biomedical Engineering
Translation:Humans
Pancreatic ductal adenocarcinoma induces neural injury that promotes a transcriptomic and functional repair signature by peripheral neuroglia. Oncogene. 2023 08; 42(34):2536-2546. Weitz J, Garg B, Martsinkovskiy A, Patel S, Tiriac H, Lowy AM. PMID: 37433986; PMCID: PMC10880465.

View in: PubMed Mentions: 2 Fields:
Mol Molecular Biology Neo Neoplasms
Translation:Humans Animals Cells
Pancreatic Ductal Adenocarcinoma Induces Neural Injury that Promotes a Transcriptomic and Functional Repair Signature by Peripheral Neuroglia. Res Sq. 2023 Mar 28. Weitz J, Garg B, Tiriac H, Martsinkovskiy A, Patel S, Lowy A. PMID: 37034696; PMCID: PMC10081383.

View in: PubMed Mentions:
Treatment of pancreatic cancer with irreversible electroporation and intratumoral CD40 antibody stimulates systemic immune responses that inhibit liver metastasis in an orthotopic model. J Immunother Cancer. 2023 01; 11(1). Shankara Narayanan JS, Hayashi T, Erdem S, McArdle S, Tiriac H, Ray P, Pu M, Mikulski Z, Miller A, Messer K, Carson D, Schoenberger S, White RR. PMID: 36634919; PMCID: PMC9843215.

View in: PubMed Mentions: 4 Fields:
Neo Neoplasms The Therapeutics
Translation:Animals
Culture and Imaging of Ex Vivo Organotypic Pseudomyxoma Peritonei Tumor Slices from Resected Human Tumor Specimens. J Vis Exp. 2022 12 09; (190). Weitz J, Montecillo Gulay KC, Hurtado de Mendoza T, Tiriac H, Baumgartner J, Kelly K, Veerapong J, Lowy AM. PMID: 36571414; PMCID: PMC10880464.

View in: PubMed Mentions: 1 Fields:
Bio Biology Med Medicine (General)
Translation:Humans Animals
An Ex Vivo Organotypic Culture Platform for Functional Interrogation of Human Appendiceal Cancer Reveals a Prominent and Heterogenous Immunological Landscape. Clin Cancer Res. 2022 11 01; 28(21):4793-4806. Weitz J, Hurtado de Mendoza T, Tiriac H, Lee J, Sun S, Garg B, Patel J, Li K, Baumgartner J, Kelly KJ, Veerapong J, Hosseini M, Chen Y, Lowy AM. PMID: 36067351.

View in: PubMed Mentions: 5 Fields:
Neo Neoplasms
Translation:Humans Animals
Patient-Derived Sarcoma Organoids Offer a Novel Platform for Personalized Precision Medicine. Ann Surg Oncol. 2022 11; 29(12):7239-7241. Sanchez-Fdez A, Sharma AK, Tiriac H, Sicklick JK. PMID: 35831519; PMCID: PMC10173699.

View in: PubMed Mentions: 2 Fields:
Gen General Surgery Neo Neoplasms
Translation:Humans
Using Organotypic Tissue Slices to Investigate the Microenvironment of Pancreatic Cancer: Pharmacotyping and Beyond. Cancers (Basel). 2021 Oct 05; 13(19). Weitz JR, Tiriac H, Hurtado de Mendoza T, Wascher A, Lowy AM. PMID: 34638476; PMCID: PMC8507648.

View in: PubMed Mentions: 8
Vestigial-like 1 is a shared targetable cancer-placenta antigen expressed by pancreatic and basal-like breast cancers. Nat Commun. 2020 10 21; 11(1):5332. Bradley SD, Talukder AH, Lai I, Davis R, Alvarez H, Tiriac H, Zhang M, Chiu Y, Melendez B, Jackson KR, Katailiha A, Sonnemann HM, Li F, Kang Y, Qiao N, Pan BF, Lorenzi PL, Hurd M, Mittendorf EA, Peterson CB, Javle M, Bristow C, Kim M, Tuveson DA, Hawke D, Kopetz S, Wolff RA, Hwu P, Maitra A, Roszik J, Yee C, Lizée G. PMID: 33087697; PMCID: PMC7577998.

View in: PubMed Mentions: 9 Fields:
Bio Biology Sci Science
Translation:Humans Cells
Isolation and Characterization of Patient-derived Pancreatic Ductal Adenocarcinoma Organoid Models. J Vis Exp. 2020 01 14; (155). Tiriac H, French R, Lowy AM. PMID: 32009658.

View in: PubMed Mentions: 2 Fields:
Bio Biology Med Medicine (General)
Translation:Humans
Organoid models for translational pancreatic cancer research. Curr Opin Genet Dev. 2019 02; 54:7-11. Tiriac H, Plenker D, Baker LA, Tuveson DA. PMID: 30844513; PMCID: PMC6722026.

View in: PubMed Mentions: 33 Fields:
Gen Genetics
Translation:Humans
Successful creation of pancreatic cancer organoids by means of EUS-guided fine-needle biopsy sampling for personalized cancer treatment. Gastrointest Endosc. 2018 Jun; 87(6):1474-1480. Tiriac H, Bucobo JC, Tzimas D, Grewel S, Lacomb JF, Rowehl LM, Nagula S, Wu M, Kim J, Sasson A, Vignesh S, Martello L, Munoz-Sagastibelza M, Somma J, Tuveson DA, Li E, Buscaglia JM. PMID: 29325707; PMCID: PMC6143289.

View in: PubMed Mentions: 80 Fields:
Dia Diagnostic Imaging Gas Gastroenterology The Therapeutics
Translation:Humans Cells
NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer. Cell. 2016 Aug 11; 166(4):963-976. Chio IIC, Jafarnejad SM, Ponz-Sarvise M, Park Y, Rivera K, Palm W, Wilson J, Sangar V, Hao Y, Öhlund D, Wright K, Filippini D, Lee EJ, Da Silva B, Schoepfer C, Wilkinson JE, Buscaglia JM, DeNicola GM, Tiriac H, Hammell M, Crawford HC, Schmidt EE, Thompson CB, Pappin DJ, Sonenberg N, Tuveson DA. PMID: 27477511; PMCID: PMC5234705.

View in: PubMed Mentions: 194 Fields:
Cel Cell Biology
Translation:Humans Animals Cells
Conjugation to the sigma-2 ligand SV119 overcomes uptake blockade and converts dm-Erastin into a potent pancreatic cancer therapeutic. Oncotarget. 2016 Jun 07; 7(23):33529-41. Ohman KA, Hashim YM, Vangveravong S, Nywening TM, Cullinan DR, Goedegebuure SP, Liu J, Van Tine BA, Tiriac H, Tuveson DA, DeNardo DG, Spitzer D, Mach RH, Hawkins WG. PMID: 27244881; PMCID: PMC5085100.

View in: PubMed Mentions: 12 Fields:
Neo Neoplasms
Translation:Humans Animals Cells
Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy. Cell. 2014 Sep 25; 159(1):80-93. Sherman MH, Yu RT, Engle DD, Ding N, Atkins AR, Tiriac H, Collisson EA, Connor F, Van Dyke T, Kozlov S, Martin P, Tseng TW, Dawson DW, Donahue TR, Masamune A, Shimosegawa T, Apte MV, Wilson JS, Ng B, Lau SL, Gunton JE, Wahl GM, Hunter T, Drebin JA, O'Dwyer PJ, Liddle C, Tuveson DA, Downes M, Evans RM. PMID: 25259922; PMCID: PMC4177038.

View in: PubMed Mentions: 514 Fields:
Cel Cell Biology
Translation:Humans Animals Cells