Sign in to edit your profile (add interests, mentoring, photo, etc.)

    Ana Kasirer-Friede

    TitleProject Scientist
    SchoolUniversity of California, San Diego
    Address9500 Gilman Drive #0726
    CA La Jolla 92093
    vCardDownload vCard

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Liao Z, Kasirer-Friede A, Shattil SJ. Optogenetic interrogation of integrin aVß3 function in endothelial cells. J Cell Sci. 2017 Sep 01. PMID: 28864764.
        View in: PubMed
      2. van Sorge NM, Cole JN, Kuipers K, Henningham A, Aziz RK, Kasirer-Friede A, Lin L, Berends ETM, Davies MR, Dougan G, Zhang F, Dahesh S, Shaw L, Gin J, Cunningham M, Merriman JA, Hütter J, Lepenies B, Rooijakkers SHM, Malley R, Walker MJ, Shattil SJ, Schlievert PM, Choudhury B, Nizet V. The classical lancefield antigen of group a Streptococcus is a virulence determinant with implications for vaccine design. Cell Host Microbe. 2014 Jun 11; 15(6):729-740. PMID: 24922575; PMCID: PMC4078075.
      3. Kasirer-Friede A, Kang J, Kahner B, Ye F, Ginsberg MH, Shattil SJ. ADAP interactions with talin and kindlin promote platelet integrin aIIbß3 activation and stable fibrinogen binding. Blood. 2014 May 15; 123(20):3156-65. PMID: 24523237; PMCID: PMC4023421.
      4. Ye F, Petrich BG, Anekal P, Lefort CT, Kasirer-Friede A, Shattil SJ, Ruppert R, Moser M, Fässler R, Ginsberg MH. The mechanism of kindlin-mediated activation of integrin aIIbß3. Curr Biol. 2013 Nov 18; 23(22):2288-95. PMID: 24210614; PMCID: PMC3912999.
      5. Mitsios JV, Prevost N, Kasirer-Friede A, Gutierrez E, Groisman A, Abrams CS, Wang Y, Litvinov RI, Zemljic-Harpf A, Ross RS, Shattil SJ. What is vinculin needed for in platelets? J Thromb Haemost. 2010 Oct; 8(10):2294-304. PMID: 20670372; PMCID: PMC2965783.
      6. Kasirer-Friede A, Ruggeri ZM, Shattil SJ. Role for ADAP in shear flow-induced platelet mechanotransduction. Blood. 2010 Mar 18; 115(11):2274-82. PMID: 19996090; PMCID: PMC2844019.
      7. Gutierrez E, Petrich BG, Shattil SJ, Ginsberg MH, Groisman A, Kasirer-Friede A. Microfluidic devices for studies of shear-dependent platelet adhesion. Lab Chip. 2008 Sep; 8(9):1486-95. PMID: 18818803; PMCID: PMC2683765.
      8. Kasirer-Friede A, Kahn ML, Shattil SJ. Platelet integrins and immunoreceptors. Immunol Rev. 2007 Aug; 218:247-64. PMID: 17624957.
        View in: PubMed
      9. Kliche S, Breitling D, Togni M, Pusch R, Heuer K, Wang X, Freund C, Kasirer-Friede A, Menasche G, Koretzky GA, Schraven B. The ADAP/SKAP55 signaling module regulates T-cell receptor-mediated integrin activation through plasma membrane targeting of Rap1. Mol Cell Biol. 2006 Oct; 26(19):7130-44. PMID: 16980616; PMCID: PMC1592884.
      10. Kasirer-Friede A, Moran B, Nagrampa-Orje J, Swanson K, Ruggeri ZM, Schraven B, Neel BG, Koretzky G, Shattil SJ. ADAP is required for normal alphaIIbbeta3 activation by VWF/GP Ib-IX-V and other agonists. Blood. 2007 Feb 01; 109(3):1018-25. PMID: 17003372; PMCID: PMC1785130.
      11. Arias-Salgado EG, Haj F, Dubois C, Moran B, Kasirer-Friede A, Furie BC, Furie B, Neel BG, Shattil SJ. PTP-1B is an essential positive regulator of platelet integrin signaling. J Cell Biol. 2005 Aug 29; 170(5):837-45. PMID: 16115959; PMCID: PMC2171339.
      12. Kasirer-Friede A, Cozzi MR, Mazzucato M, De Marco L, Ruggeri ZM, Shattil SJ. Signaling through GP Ib-IX-V activates alpha IIb beta 3 independently of other receptors. Blood. 2004 May 01; 103(9):3403-11. PMID: 14726383.
        View in: PubMed
      13. Arya M, López JA, Romo GM, Cruz MA, Kasirer-Friede A, Shattil SJ, Anvari B. Glycoprotein Ib-IX-mediated activation of integrin alpha(IIb)beta(3): effects of receptor clustering and von Willebrand factor adhesion. J Thromb Haemost. 2003 Jun; 1(6):1150-7. PMID: 12871313.
        View in: PubMed
      14. Kasirer-Friede A, Ware J, Leng L, Marchese P, Ruggeri ZM, Shattil SJ. Lateral clustering of platelet GP Ib-IX complexes leads to up-regulation of the adhesive function of integrin alpha IIbbeta 3. J Biol Chem. 2002 Apr 05; 277(14):11949-56. PMID: 11812775.
        View in: PubMed
      15. Kasirer-Friede A, Legrand C, Frojmovic MM. Complementary roles for fibrin(ogen), thrombospondin and vWF in mediating shear-dependent aggregation of platelets stimulated at threshold thrombin concentrations. Thromb Haemost. 2001 Aug; 86(2):653-9. PMID: 11522018.
        View in: PubMed
      16. Kasirer-Friede A, Legrand C, Frojmovic MM. Thrombin receptor occupancy modulates aggregation efficiency and platelet surface expression of vWF and thrombospondin at low thrombin concentrations. Thromb Haemost. 1999 Jun; 81(6):967-75. PMID: 10404777.
        View in: PubMed
      17. Kasirer-Friede A, Frojmovic MM. Ristocetin- and thrombin-induced platelet aggregation at physiological shear rates: differential roles for GPIb and GPIIb-IIIa receptor. Thromb Haemost. 1998 Sep; 80(3):428-36. PMID: 9759623.
        View in: PubMed
      18. Liu Q, Rooney MM, Kasirer-Friede A, Brown E, Lord ST, Frojmovic MM. Role of the gamma chain Ala-Gly-Asp-Val and Aalpha chain Arg-Gly-Asp-Ser sites of fibrinogen in coaggregation of platelets and fibrinogen-coated beads. Biochim Biophys Acta. 1998 Jun 11; 1385(1):33-42. PMID: 9630497.
        View in: PubMed
      19. Frojmovic MM, Kasirer-Friede A, Goldsmith HL, Brown EA. Surface-secreted von Willebrand factor mediates aggregation of ADP-activated platelets at moderate shear stress: facilitated by GPIb but controlled by GPIIb-IIIa. Thromb Haemost. 1997 Mar; 77(3):568-76. PMID: 9066012.
        View in: PubMed
      20. Frojmovic M, Brown E, Kasirer-Friede A, Liu Q. Limitations and warnings in use of labelled (fibrinogen) ligands to cell receptors. Thromb Haemost. 1996 Jul; 76(1):124. PMID: 8819264.
        View in: PubMed
      21. Xia Z, Wong T, Liu Q, Kasirer-Friede A, Brown E, Frojmovic MM. Optimally functional fluorescein isothiocyanate-labelled fibrinogen for quantitative studies of binding to activated platelets and platelet aggregation. Br J Haematol. 1996 Apr; 93(1):204-14. PMID: 8611461.
        View in: PubMed