Ana Kasirer-Friede

Title(s)Project Scientist, Medicine
SchoolHealth Sciences
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Kasirer-Friede A, Tjahjono W, Eto K, Shattil SJ. SHARPIN at the nexus of integrin, immune, and inflammatory signaling in human platelets. Proc Natl Acad Sci U S A. 2019 03 12; 116(11):4983-4988. PMID: 30804189.
      View in: PubMed
    2. Kasirer-Friede A. Editorial: Molecular Bridges Between Hematology and Inflammation. Front Med (Lausanne). 2019; 6:17. PMID: 30800659.
      View in: PubMed
    3. Liao Z, Kasirer-Friede A, Shattil SJ. Optogenetic interrogation of integrin aVß3 function in endothelial cells. J Cell Sci. 2017 Oct 15; 130(20):3532-3541. PMID: 28864764.
      View in: PubMed
    4. van Sorge NM, Cole JN, Kuipers K, Henningham A, Aziz RK, Kasirer-Friede A, Lin L, Berends ETM, Davies MR, Dougan G, Zhang F, Dahesh S, Shaw L, Gin J, Cunningham M, Merriman JA, Hütter J, Lepenies B, Rooijakkers SHM, Malley R, Walker MJ, Shattil SJ, Schlievert PM, Choudhury B, Nizet V. The classical lancefield antigen of group a Streptococcus is a virulence determinant with implications for vaccine design. Cell Host Microbe. 2014 Jun 11; 15(6):729-740. PMID: 24922575; PMCID: PMC4078075.
    5. Kasirer-Friede A, Kang J, Kahner B, Ye F, Ginsberg MH, Shattil SJ. ADAP interactions with talin and kindlin promote platelet integrin aIIbß3 activation and stable fibrinogen binding. Blood. 2014 May 15; 123(20):3156-65. PMID: 24523237.
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    6. Ye F, Petrich BG, Anekal P, Lefort CT, Kasirer-Friede A, Shattil SJ, Ruppert R, Moser M, Fässler R, Ginsberg MH. The mechanism of kindlin-mediated activation of integrin aIIbß3. Curr Biol. 2013 Nov 18; 23(22):2288-2295. PMID: 24210614.
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    7. Mitsios JV, Prevost N, Kasirer-Friede A, Gutierrez E, Groisman A, Abrams CS, Wang Y, Litvinov RI, Zemljic-Harpf A, Ross RS, Shattil SJ. What is vinculin needed for in platelets? J Thromb Haemost. 2010 Oct; 8(10):2294-304. PMID: 20670372; PMCID: PMC2965783.
    8. Kasirer-Friede A, Ruggeri ZM, Shattil SJ. Role for ADAP in shear flow-induced platelet mechanotransduction. Blood. 2010 Mar 18; 115(11):2274-82. PMID: 19996090; PMCID: PMC2844019.
    9. Gutierrez E, Petrich BG, Shattil SJ, Ginsberg MH, Groisman A, Kasirer-Friede A. Microfluidic devices for studies of shear-dependent platelet adhesion. Lab Chip. 2008 Sep; 8(9):1486-95. PMID: 18818803; PMCID: PMC2683765.
    10. Kasirer-Friede A, Kahn ML, Shattil SJ. Platelet integrins and immunoreceptors. Immunol Rev. 2007 Aug; 218:247-64. PMID: 17624957.
      View in: PubMed
    11. Kliche S, Breitling D, Togni M, Pusch R, Heuer K, Wang X, Freund C, Kasirer-Friede A, Menasche G, Koretzky GA, Schraven B. The ADAP/SKAP55 signaling module regulates T-cell receptor-mediated integrin activation through plasma membrane targeting of Rap1. Mol Cell Biol. 2006 Oct; 26(19):7130-44. PMID: 16980616; PMCID: PMC1592884.
    12. Kasirer-Friede A, Moran B, Nagrampa-Orje J, Swanson K, Ruggeri ZM, Schraven B, Neel BG, Koretzky G, Shattil SJ. ADAP is required for normal alphaIIbbeta3 activation by VWF/GP Ib-IX-V and other agonists. Blood. 2007 Feb 01; 109(3):1018-25. PMID: 17003372; PMCID: PMC1785130.
    13. Arias-Salgado EG, Haj F, Dubois C, Moran B, Kasirer-Friede A, Furie BC, Furie B, Neel BG, Shattil SJ. PTP-1B is an essential positive regulator of platelet integrin signaling. J Cell Biol. 2005 Aug 29; 170(5):837-45. PMID: 16115959; PMCID: PMC2171339.
    14. Kasirer-Friede A, Cozzi MR, Mazzucato M, De Marco L, Ruggeri ZM, Shattil SJ. Signaling through GP Ib-IX-V activates alpha IIb beta 3 independently of other receptors. Blood. 2004 May 01; 103(9):3403-11. PMID: 14726383.
      View in: PubMed
    15. Arya M, López JA, Romo GM, Cruz MA, Kasirer-Friede A, Shattil SJ, Anvari B. Glycoprotein Ib-IX-mediated activation of integrin alpha(IIb)beta(3): effects of receptor clustering and von Willebrand factor adhesion. J Thromb Haemost. 2003 Jun; 1(6):1150-7. PMID: 12871313.
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    16. Kasirer-Friede A, Ware J, Leng L, Marchese P, Ruggeri ZM, Shattil SJ. Lateral clustering of platelet GP Ib-IX complexes leads to up-regulation of the adhesive function of integrin alpha IIbbeta 3. J Biol Chem. 2002 Apr 05; 277(14):11949-56. PMID: 11812775.
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    17. Kasirer-Friede A, Frojmovic MM. Ristocetin- and thrombin-induced platelet aggregation at physiological shear rates: differential roles for GPIb and GPIIb-IIIa receptor. Thromb Haemost. 1998 Sep; 80(3):428-36. PMID: 9759623.
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    18. Frojmovic MM, Kasirer-Friede A, Goldsmith HL, Brown EA. Surface-secreted von Willebrand factor mediates aggregation of ADP-activated platelets at moderate shear stress: facilitated by GPIb but controlled by GPIIb-IIIa. Thromb Haemost. 1997 Mar; 77(3):568-76. PMID: 9066012.
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    19. Xia Z, Wong T, Liu Q, Kasirer-Friede A, Brown E, Frojmovic MM. Optimally functional fluorescein isothiocyanate-labelled fibrinogen for quantitative studies of binding to activated platelets and platelet aggregation. Br J Haematol. 1996 Apr; 93(1):204-14. PMID: 8611461.
      View in: PubMed