Richard Firtel

Title(s)Emeritus Professor, Cell and Developmental Biology
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    Bio-Mechanics of Directional Migration of Leukocytes
    NIH R01GM084227Sep 30, 2010 - Jun 30, 2020
    Role: Principal Investigator
    CHEMOTAXIS IN DICTYOSTELIUM DISCOIDEUM: AN INTEGRATIVE APPROACH
    NIH P01GM078586Jul 1, 2006 - Jul 31, 2017
    Role: Co-Investigator
    Role of Rac and Rac Effectors in Controlling Chemotaxis
    NIH R01GM062847Jan 1, 2002 - Dec 31, 2006
    Role: Principal Investigator
    Comprehensive Biology: Exploiting the Yeast Genome
    NIH P41RR011823Sep 30, 1996 - Jun 30, 2016
    Role: Co-Investigator
    IVEM and Image Analysis Resource
    NIH P41RR004050Dec 12, 1988 - Mar 31, 2014
    Role: Co-Investigator
    Signalling Processes in Dictyostelium
    NIH R01GM037830Jul 1, 1986 - Jan 31, 2017
    Role: Principal Investigator
    ANALYSIS OF DEVELOPMENTALLY REGULATED GENES
    NIH R01GM030693Apr 1, 1982 - Mar 31, 1992
    Role: Principal Investigator
    Gene Structure and Transciptional Regulation
    NIH R01GM024279Sep 1, 1977 - Feb 28, 2009
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Phosphodiesterase PdeD, dynacortin, and a Kelch repeat-containing protein are direct GSK3 substrates in Dictyostelium that contribute to chemotaxis towards cAMP. Environ Microbiol. 2018 05; 20(5):1888-1903. Baumgardner K, Lin C, Firtel RA, Lacal J. PMID: 29626371.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    2. The Dictyostelium GSK3 kinase GlkA coordinates signal relay and chemotaxis in response to growth conditions. Dev Biol. 2018 03 01; 435(1):56-72. Lacal Romero J, Shen Z, Baumgardner K, Wei J, Briggs SP, Firtel RA. PMID: 29355521.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    3. Two-Layer Elastographic 3-D Traction Force Microscopy. Sci Rep. 2017 01 11; 7:39315. Álvarez-González B, Zhang S, Gómez-González M, Meili R, Firtel RA, Lasheras JC, Del Álamo JC. PMID: 28074837; PMCID: PMC5225457.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    4. Connecting G protein signaling to chemoattractant-mediated cell polarity and cytoskeletal reorganization. Small GTPases. 2018 07 04; 9(4):360-364. Liu Y, Lacal J, Firtel RA, Kortholt A. PMID: 27715492; PMCID: PMC5997169.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    5. A Gα-Stimulated RapGEF Is a Receptor-Proximal Regulator of Dictyostelium Chemotaxis. Dev Cell. 2016 Jun 06; 37(5):458-72. Liu Y, Lacal J, Veltman DM, Fusetti F, van Haastert PJ, Firtel RA, Kortholt A. PMID: 27237792.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    6. Cooperative cell motility during tandem locomotion of amoeboid cells. Mol Biol Cell. 2016 Apr 15; 27(8):1262-71. Bastounis E, Álvarez-González B, del Álamo JC, Lasheras JC, Firtel RA. PMID: 26912787; PMCID: PMC4831880.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    7. Three-dimensional balance of cortical tension and axial contractility enables fast amoeboid migration. Biophys J. 2015 Feb 17; 108(4):821-832. Álvarez-González B, Meili R, Bastounis E, Firtel RA, Lasheras JC, Del Álamo JC. PMID: 25692587; PMCID: PMC4336364.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    8. Cytoskeletal Mechanics Regulating Amoeboid Cell Locomotion. Appl Mech Rev. 2014 Jun 05; 66(5). Alvarez-González B, Meili R, Firtel R, Bastounis E, Del Álamo JC, Lasheras JC. PMID: 25328163; PMCID: PMC4201387.
      View in: PubMed   Mentions: 7  
    9. Both contractile axial and lateral traction force dynamics drive amoeboid cell motility. J Cell Biol. 2014 Mar 17; 204(6):1045-61. Bastounis E, Meili R, Álvarez-González B, Francois J, del Álamo JC, Firtel RA, Lasheras JC. PMID: 24637328; PMCID: PMC3998796.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    10. Degradation of activated K-Ras orthologue via K-Ras-specific lysine residues is required for cytokinesis. J Biol Chem. 2014 Feb 14; 289(7):3950-9. Sumita K, Yoshino H, Sasaki M, Majd N, Kahoud ER, Takahashi H, Takeuchi K, Kuroda T, Lee S, Charest PG, Takeda K, Asara JM, Firtel RA, Anastasiou D, Sasaki AT. PMID: 24338482; PMCID: PMC3924263.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    11. Three-dimensional quantification of cellular traction forces and mechanosensing of thin substrata by fourier traction force microscopy. PLoS One. 2013; 8(9):e69850. del Álamo JC, Meili R, Álvarez-González B, Alonso-Latorre B, Bastounis E, Firtel R, Lasheras JC. PMID: 24023712; PMCID: PMC3762859.
      View in: PubMed   Mentions: 53     Fields:    Translation:Animals
    12. Daydreamer, a Ras effector and GSK-3 substrate, is important for directional sensing and cell motility. Mol Biol Cell. 2013 Jan; 24(2):100-14. Kölsch V, Shen Z, Lee S, Plak K, Lotfi P, Chang J, Charest PG, Romero JL, Jeon TJ, Kortholt A, Briggs SP, Firtel RA. PMID: 23135995; PMCID: PMC3541958.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    13. Adaptation in a eukaryotic pathway: combining experiments with modeling. Cell Cycle. 2012 Mar 15; 11(6):1051-2. Rappel WJ, Firtel RA. PMID: 22391206; PMCID: PMC3335914.
      View in: PubMed   Mentions: 3     Fields:    
    14. A mechanosensory system governs myosin II accumulation in dividing cells. Mol Biol Cell. 2012 Apr; 23(8):1510-23. Kee YS, Ren Y, Dorfman D, Iijima M, Firtel R, Iglesias PA, Robinson DN. PMID: 22379107; PMCID: PMC3327329.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    15. Incoherent feedforward control governs adaptation of activated ras in a eukaryotic chemotaxis pathway. Sci Signal. 2012 Jan 03; 5(205):ra2. Takeda K, Shao D, Adler M, Charest PG, Loomis WF, Levine H, Groisman A, Rappel WJ, Firtel RA. PMID: 22215733; PMCID: PMC3928814.
      View in: PubMed   Mentions: 88     Fields:    Translation:Animals
    16. The SCAR/WAVE complex is necessary for proper regulation of traction stresses during amoeboid motility. Mol Biol Cell. 2011 Nov; 22(21):3995-4003. Bastounis E, Meili R, Alonso-Latorre B, del Álamo JC, Lasheras JC, Firtel RA. PMID: 21900496; PMCID: PMC3204062.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    17. Activated membrane patches guide chemotactic cell motility. PLoS Comput Biol. 2011 Jun; 7(6):e1002044. Hecht I, Skoge ML, Charest PG, Ben-Jacob E, Firtel RA, Loomis WF, Levine H, Rappel WJ. PMID: 21738453; PMCID: PMC3127810.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    18. An Oscillatory Contractile Pole-Force Component Dominates the Traction Forces Exerted by Migrating Amoeboid Cells. Cell Mol Bioeng. 2011 Dec; 4(4):603-615. Alonso-Latorre B, Del Álamo JC, Meili R, Firtel RA, Lasheras JC. PMID: 22207880; PMCID: PMC3234362.
      View in: PubMed   Mentions: 7  
    19. The LRRK2-related Roco kinase Roco2 is regulated by Rab1A and controls the actin cytoskeleton. Mol Biol Cell. 2011 Jul 01; 22(13):2198-211. Kicka S, Shen Z, Annesley SJ, Fisher PR, Lee S, Briggs S, Firtel RA. PMID: 21551065; PMCID: PMC3128523.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    20. "TORCing" neutrophil chemotaxis. Dev Cell. 2010 Dec 14; 19(6):795-6. Charest PG, Firtel RA. PMID: 21145496; PMCID: PMC3033560.
      View in: PubMed   Mentions: 5     Fields:    
    21. A Ras signaling complex controls the RasC-TORC2 pathway and directed cell migration. Dev Cell. 2010 May 18; 18(5):737-49. Charest PG, Shen Z, Lakoduk A, Sasaki AT, Briggs SP, Firtel RA. PMID: 20493808; PMCID: PMC2893887.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansAnimalsCells
    22. Involvement of the cytoskeleton in controlling leading-edge function during chemotaxis. Mol Biol Cell. 2010 Jun 01; 21(11):1810-24. Lee S, Shen Z, Robinson DN, Briggs S, Firtel RA. PMID: 20375144; PMCID: PMC2877640.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    23. Myosin II is essential for the spatiotemporal organization of traction forces during cell motility. Mol Biol Cell. 2010 Feb 01; 21(3):405-17. Meili R, Alonso-Latorre B, del Alamo JC, Firtel RA, Lasheras JC. PMID: 19955212; PMCID: PMC2814786.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    24. Mechanosensing through cooperative interactions between myosin II and the actin crosslinker cortexillin I. Curr Biol. 2009 Sep 15; 19(17):1421-8. Ren Y, Effler JC, Norstrom M, Luo T, Firtel RA, Iglesias PA, Rock RS, Robinson DN. PMID: 19646871; PMCID: PMC2763054.
      View in: PubMed   Mentions: 90     Fields:    Translation:AnimalsCells
    25. Regulation of Dictyostelium morphogenesis by RapGAP3. Dev Biol. 2009 Apr 15; 328(2):210-20. Jeon TJ, Lee S, Weeks G, Firtel RA. PMID: 19284976.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    26. Distribution of traction forces associated with shape changes during amoeboid cell migration. Annu Int Conf IEEE Eng Med Biol Soc. 2009; 2009:3346-9. Alonso-Latorre B, Meili R, Bastounis E, Del Alamo JC, Firtel R, Lasheras JC. PMID: 19964075; PMCID: PMC6157266.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    27. Spatiotemporal regulation of Ras-GTPases during chemotaxis. Methods Mol Biol. 2009; 571:333-48. Sasaki AT, Firtel RA. PMID: 19763978.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    28. Dictyostelium Dock180-related RacGEFs regulate the actin cytoskeleton during cell motility. Mol Biol Cell. 2009 Jan; 20(2):699-707. Para A, Krischke M, Merlot S, Shen Z, Oberholzer M, Lee S, Briggs S, Firtel RA. PMID: 19037099; PMCID: PMC2626555.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    29. Spatiotemporal regulation of Ras activity provides directional sensing. Curr Biol. 2008 Oct 28; 18(20):1587-1593. Zhang S, Charest PG, Firtel RA. PMID: 18948008; PMCID: PMC2590931.
      View in: PubMed   Mentions: 68     Fields:    Translation:Animals
    30. Regulation of contractile vacuole formation and activity in Dictyostelium. EMBO J. 2008 Aug 06; 27(15):2064-76. Du F, Edwards K, Shen Z, Sun B, De Lozanne A, Briggs S, Firtel RA. PMID: 18636095; PMCID: PMC2516880.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    31. Directional sensing during chemotaxis. FEBS Lett. 2008 Jun 18; 582(14):2075-85. Janetopoulos C, Firtel RA. PMID: 18452713; PMCID: PMC2519798.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansAnimalsCells
    32. The regulation of cell motility and chemotaxis by phospholipid signaling. J Cell Sci. 2008 Mar 01; 121(Pt 5):551-9. Kölsch V, Charest PG, Firtel RA. PMID: 18287584; PMCID: PMC2671295.
      View in: PubMed   Mentions: 192     Fields:    Translation:HumansAnimalsCells
    33. Evidence that DIF-1 and hyper-osmotic stress activate a Dictyostelium STAT by inhibiting a specific protein tyrosine phosphatase. Development. 2008 Apr; 135(7):1347-53. Araki T, Langenick J, Gamper M, Firtel RA, Williams JG. PMID: 18305004; PMCID: PMC2671291.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    34. Regulation of Rap1 activity by RapGAP1 controls cell adhesion at the front of chemotaxing cells. J Cell Biol. 2007 Dec 03; 179(5):833-43. Jeon TJ, Lee DJ, Lee S, Weeks G, Firtel RA. PMID: 18039932; PMCID: PMC2099181.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    35. Spatio-temporal analysis of eukaryotic cell motility by improved force cytometry. Proc Natl Acad Sci U S A. 2007 Aug 14; 104(33):13343-8. Del Alamo JC, Meili R, Alonso-Latorre B, Rodríguez-Rodríguez J, Aliseda A, Firtel RA, Lasheras JC. PMID: 17684097; PMCID: PMC1940228.
      View in: PubMed   Mentions: 103     Fields:    Translation:Animals
    36. G protein-independent Ras/PI3K/F-actin circuit regulates basic cell motility. J Cell Biol. 2007 Jul 16; 178(2):185-91. Sasaki AT, Janetopoulos C, Lee S, Charest PG, Takeda K, Sundheimer LW, Meili R, Devreotes PN, Firtel RA. PMID: 17635933; PMCID: PMC2064438.
      View in: PubMed   Mentions: 119     Fields:    Translation:AnimalsCells
    37. Rap1 controls cell adhesion and cell motility through the regulation of myosin II. J Cell Biol. 2007 Mar 26; 176(7):1021-33. Jeon TJ, Lee DJ, Merlot S, Weeks G, Firtel RA. PMID: 17371831; PMCID: PMC2064086.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    38. MEK1 and protein phosphatase 4 coordinate Dictyostelium development and chemotaxis. Mol Cell Biol. 2007 May; 27(10):3817-27. Mendoza MC, Booth EO, Shaulsky G, Firtel RA. PMID: 17353263; PMCID: PMC1899987.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    39. Role of phosphatidylinositol 3-kinases in chemotaxis in Dictyostelium. J Biol Chem. 2007 Apr 20; 282(16):11874-84. Takeda K, Sasaki AT, Ha H, Seung HA, Firtel RA. PMID: 17331950.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    40. Big roles for small GTPases in the control of directed cell movement. Biochem J. 2007 Jan 15; 401(2):377-90. Charest PG, Firtel RA. PMID: 17173542; PMCID: PMC1820805.
      View in: PubMed   Mentions: 85     Fields:    Translation:AnimalsCells
    41. Feedback signaling controls leading-edge formation during chemotaxis. Curr Opin Genet Dev. 2006 Aug; 16(4):339-47. Charest PG, Firtel RA. PMID: 16806895.
      View in: PubMed   Mentions: 81     Fields:    Translation:AnimalsCells
    42. Regulation of chemotaxis by the orchestrated activation of Ras, PI3K, and TOR. Eur J Cell Biol. 2006 Sep; 85(9-10):873-95. Sasaki AT, Firtel RA. PMID: 16740339.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimalsCells
    43. Assaying chemotaxis of Dictyostelium cells. Methods Mol Biol. 2006; 346:393-405. Mendoza MC, Firtel RA. PMID: 16957303.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    44. Loss of SMEK, a novel, conserved protein, suppresses MEK1 null cell polarity, chemotaxis, and gene expression defects. Mol Cell Biol. 2005 Sep; 25(17):7839-53. Mendoza MC, Du F, Iranfar N, Tang N, Ma H, Loomis WF, Firtel RA. PMID: 16107728; PMCID: PMC1190274.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    45. TOR complex 2 integrates cell movement during chemotaxis and signal relay in Dictyostelium. Mol Biol Cell. 2005 Oct; 16(10):4572-83. Lee S, Comer FI, Sasaki A, McLeod IX, Duong Y, Okumura K, Yates JR, Parent CA, Firtel RA. PMID: 16079174; PMCID: PMC1237065.
      View in: PubMed   Mentions: 110     Fields:    Translation:AnimalsCells
    46. Rho Rocks PTEN. Nat Cell Biol. 2005 Apr; 7(4):334-5. Meili R, Sasaki AT, Firtel RA. PMID: 15803130.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    47. A Dictyostelium homologue of WASP is required for polarized F-actin assembly during chemotaxis. Mol Biol Cell. 2005 May; 16(5):2191-206. Myers SA, Han JW, Lee Y, Firtel RA, Chung CY. PMID: 15728724; PMCID: PMC1087228.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    48. Finding the way: directional sensing and cell polarization through Ras signalling. Novartis Found Symp. 2005; 269:73-87; discussion 87-91, 223-30. Sasaki AT, Firtel RA. PMID: 16355536.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    49. Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement. J Cell Biol. 2004 Nov 08; 167(3):505-18. Sasaki AT, Chun C, Takeda K, Firtel RA. PMID: 15534002; PMCID: PMC2172490.
      View in: PubMed   Mentions: 208     Fields:    Translation:HumansAnimalsCells
    50. Dictyostelium PAKc is required for proper chemotaxis. Mol Biol Cell. 2004 Dec; 15(12):5456-69. Lee S, Rivero F, Park KC, Huang E, Funamoto S, Firtel RA. PMID: 15483055; PMCID: PMC532025.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    51. Rac regulation of chemotaxis and morphogenesis in Dictyostelium. EMBO J. 2004 Oct 27; 23(21):4177-89. Park KC, Rivero F, Meili R, Lee S, Apone F, Firtel RA. PMID: 15470506; PMCID: PMC524383.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    52. Breaking symmetries: regulation of Dictyostelium development through chemoattractant and morphogen signal-response. Curr Opin Genet Dev. 2004 Oct; 14(5):540-9. Kimmel AR, Firtel RA. PMID: 15380246.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    53. Insights into morphogenesis from a simple developmental system. Nat Rev Mol Cell Biol. 2004 Jul; 5(7):531-41. Chisholm RL, Firtel RA. PMID: 15232571.
      View in: PubMed   Mentions: 71     Fields:    Translation:Animals
    54. Cell migration: integrating signals from front to back. Science. 2003 Dec 05; 302(5651):1704-9. Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Ginsberg MH, Borisy G, Parsons JT, Horwitz AR. PMID: 14657486.
      View in: PubMed   Mentions: 2024     Fields:    Translation:HumansAnimalsCells
    55. The novel ankyrin-repeat containing kinase ARCK-1 acts as a suppressor of the Spalten signaling pathway during Dictyostelium development. Dev Biol. 2003 Nov 15; 263(2):308-22. Aubry L, Lee S, Ravanel K, Firtel RA. PMID: 14597204.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    56. Dictyostelium stress-activated protein kinase alpha, a novel stress-activated mitogen-activated protein kinase kinase kinase-like kinase, is important for the proper regulation of the cytoskeleton. Mol Biol Cell. 2003 Nov; 14(11):4526-40. Sun B, Ma H, Firtel RA. PMID: 14593072; PMCID: PMC266770.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    57. Leading the way: Directional sensing through phosphatidylinositol 3-kinase and other signaling pathways. J Cell Sci. 2003 Sep 01; 116(Pt 17):3471-8. Merlot S, Firtel RA. PMID: 12893811.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansAnimalsCells
    58. Two poles and a compass. Cell. 2003 Jul 25; 114(2):153-6. Meili R, Firtel RA. PMID: 12887916.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    59. A PTEN-related 5-phosphatidylinositol phosphatase localized in the Golgi. J Biol Chem. 2003 Oct 10; 278(41):39866-73. Merlot S, Meili R, Pagliarini DJ, Maehama T, Dixon JE, Firtel RA. PMID: 12878591.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    60. A regulator of G protein signaling-containing kinase is important for chemotaxis and multicellular development in dictyostelium. Mol Biol Cell. 2003 Apr; 14(4):1727-43. Sun B, Firtel RA. PMID: 12686622; PMCID: PMC153135.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    61. Follow the leader. Dev Cell. 2003 Mar; 4(3):291-3. Meili R, Firtel RA. PMID: 12636911.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    62. Receptor-mediated regulation of PI3Ks confines PI(3,4,5)P3 to the leading edge of chemotaxing cells. Mol Biol Cell. 2003 May; 14(5):1913-22. Huang YE, Iijima M, Parent CA, Funamoto S, Firtel RA, Devreotes P. PMID: 12802064; PMCID: PMC165086.
      View in: PubMed   Mentions: 96     Fields:    Translation:AnimalsCells
    63. Leading the way. Nat Cell Biol. 2002 Jul; 4(7):E171. Meili R, Firtel RA. PMID: 12105427.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    64. Signaling pathways at the leading edge of chemotaxing cells. J Muscle Res Cell Motil. 2002; 23(7-8):773-9. Chung CY, Firtel RA. PMID: 12952075.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    65. Signaling pathways controlling cell polarity and chemotaxis. Trends Biochem Sci. 2001 Sep; 26(9):557-66. Chung CY, Funamoto S, Firtel RA. PMID: 11551793.
      View in: PubMed   Mentions: 92     Fields:    Translation:AnimalsCells
    66. Role of phosphatidylinositol 3' kinase and a downstream pleckstrin homology domain-containing protein in controlling chemotaxis in dictyostelium. J Cell Biol. 2001 May 14; 153(4):795-810. Funamoto S, Milan K, Meili R, Firtel RA. PMID: 11352940; PMCID: PMC2192389.
      View in: PubMed   Mentions: 104     Fields:    Translation:AnimalsCells
    67. The phosphorylated C-terminus of cAR1 plays a role in cell-type-specific gene expression and STATa tyrosine phosphorylation. Dev Biol. 2001 May 01; 233(1):225-36. Briscoe C, Moniakis J, Kim JY, Brown JM, Hereld D, Devreotes PN, Firtel RA. PMID: 11319871.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    68. Protein tyrosine phosphatase PTP1 negatively regulates Dictyostelium STATa and is required for proper cell-type proportioning. Dev Biol. 2001 Apr 01; 232(1):233-45. Early A, Gamper M, Moniakis J, Kim E, Hunter T, Williams JG, Firtel RA. PMID: 11254360.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    69. An SH2-domain-containing kinase negatively regulates the phosphatidylinositol-3 kinase pathway. Genes Dev. 2001 Mar 15; 15(6):687-98. Moniakis J, Funamoto S, Fukuzawa M, Meisenhelder J, Araki T, Abe T, Meili R, Hunter T, Williams J, Firtel RA. PMID: 11274054; PMCID: PMC312652.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    70. The membrane glycoprotein gp150 is encoded by the lagC gene and mediates cell-cell adhesion by heterophilic binding during Dictyostelium development. Dev Biol. 2000 Nov 15; 227(2):734-45. Wang J, Hou L, Awrey D, Loomis WF, Firtel RA, Siu CH. PMID: 11071787.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    71. HAPPY days for the Dictyostelium genome project. Genome Res. 2000 Nov; 10(11):1658-9. Williams JG, Firtel RA. PMID: 11076849.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    72. Dictyostelium: a model for regulated cell movement during morphogenesis. Curr Opin Genet Dev. 2000 Aug; 10(4):421-7. Firtel RA, Meili R. PMID: 10889066.
      View in: PubMed   Mentions: 30     Fields:    Translation:Animals
    73. An F-Box/WD40 repeat-containing protein important for Dictyostelium cell-type proportioning, slug behaviour, and culmination. Dev Biol. 2000 Aug 01; 224(1):42-59. Nelson MK, Clark A, Abe T, Nomura A, Yadava N, Funair CJ, Jermyn KA, Mohanty S, Firtel RA, Williams JG. PMID: 10898960.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    74. The molecular genetics of chemotaxis: sensing and responding to chemoattractant gradients. Bioessays. 2000 Jul; 22(7):603-15. Firtel RA, Chung CY. PMID: 10878573.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    75. A novel Akt/PKB-related kinase is essential for morphogenesis in Dictyostelium. Curr Biol. 2000 Jun 15; 10(12):708-17. Meili R, Ellsworth C, Firtel RA. PMID: 10873800.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    76. Role of Rac in controlling the actin cytoskeleton and chemotaxis in motile cells. Proc Natl Acad Sci U S A. 2000 May 09; 97(10):5225-30. Chung CY, Lee S, Briscoe C, Ellsworth C, Firtel RA. PMID: 10805781; PMCID: PMC25810.
      View in: PubMed   Mentions: 57     Fields:    Translation:AnimalsCells
    77. Just the right size: cell counting in Dictyostelium. Trends Genet. 2000 May; 16(5):191-3. Brown JM, Firtel RA. PMID: 10782107.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    78. The Dictyostelium LIM domain-containing protein LIM2 is essential for proper chemotaxis and morphogenesis. Mol Biol Cell. 2000 Apr; 11(4):1275-91. Chien S, Chung CY, Sukumaran S, Osborne N, Lee S, Ellsworth C, McNally JG, Firtel RA. PMID: 10749929; PMCID: PMC14846.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    79. Regulation of cell-fate determination in Dictyostelium. Dev Biol. 1999 Dec 15; 216(2):426-41. Brown JM, Firtel RA. PMID: 10642783.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    80. Control of spatial patterning and cell-type proportioning in Dictyostelium. Semin Cell Dev Biol. 1999 Dec; 10(6):597-607. Mohanty S, Firtel RA. PMID: 10706824.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    81. PAKa, a putative PAK family member, is required for cytokinesis and the regulation of the cytoskeleton in Dictyostelium discoideum cells during chemotaxis. J Cell Biol. 1999 Nov 01; 147(3):559-76. Chung CY, Firtel RA. PMID: 10545500; PMCID: PMC2151188.
      View in: PubMed   Mentions: 72     Fields:    Translation:AnimalsCells
    82. A novel Ras-interacting protein required for chemotaxis and cyclic adenosine monophosphate signal relay in Dictyostelium. Mol Biol Cell. 1999 Sep; 10(9):2829-45. Lee S, Parent CA, Insall R, Firtel RA. PMID: 10473630; PMCID: PMC25521.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    83. Evidence that the Dictyostelium Dd-STATa protein is a repressor that regulates commitment to stalk cell differentiation and is also required for efficient chemotaxis. Development. 1999 Aug; 126(15):3391-405. Mohanty S, Jermyn KA, Early A, Kawata T, Aubry L, Ceccarelli A, Schaap P, Williams JG, Firtel RA. PMID: 10393118.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    84. Regulation of Dictyostelium protein-tyrosine phosphatase-3 (PTP3) through osmotic shock and stress stimulation and identification of pp130 as a PTP3 substrate. J Biol Chem. 1999 Apr 23; 274(17):12129-38. Gamper M, Kim E, Howard PK, Ma H, Hunter T, Firtel RA. PMID: 10207040.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    85. Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium. EMBO J. 1999 Apr 15; 18(8):2092-105. Meili R, Ellsworth C, Lee S, Reddy TB, Ma H, Firtel RA. PMID: 10205164; PMCID: PMC1171294.
      View in: PubMed   Mentions: 170     Fields:    Translation:AnimalsCells
    86. Integration of signaling networks that regulate Dictyostelium differentiation. Annu Rev Cell Dev Biol. 1999; 15:469-517. Aubry L, Firtel R. PMID: 10611970.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    87. A novel, putative MEK kinase controls developmental timing and spatial patterning in Dictyostelium and is regulated by ubiquitin-mediated protein degradation. Genes Dev. 1998 Nov 15; 12(22):3564-78. Chung CY, Reddy TB, Zhou K, Firtel RA. PMID: 9832508; PMCID: PMC317245.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    88. Phosphorelay signalling: new tricks for an ancient pathway. Curr Biol. 1998 Sep 10; 8(18):R662-5. Brown JM, Firtel RA. PMID: 9740798.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    89. lagC-null and gbf-null cells define key steps in the morphogenesis of Dictyostelium mounds. Dev Biol. 1998 Aug 01; 200(1):16-26. Sukumaran S, Brown JM, Firtel RA, McNally JG. PMID: 9698452.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    90. Developmentally and spatially regulated activation of a Dictyostelium STAT protein by a serpentine receptor. EMBO J. 1998 Jul 15; 17(14):4018-28. Araki T, Gamper M, Early A, Fukuzawa M, Abe T, Kawata T, Kim E, Firtel RA, Williams JG. PMID: 9670017; PMCID: PMC1170735.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    91. Identification and analysis of a gene that is essential for morphogenesis and prespore cell differentiation in Dictyostelium. Development. 1998 Jul; 125(14):2565-76. Yasukawa H, Mohanty S, Firtel RA. PMID: 9636072.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    92. Spalten, a protein containing Galpha-protein-like and PP2C domains, is essential for cell-type differentiation in Dictyostelium. Genes Dev. 1998 May 15; 12(10):1525-38. Aubry L, Firtel RA. PMID: 9585512; PMCID: PMC316834.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    93. Coexpression of a constitutively active plasma membrane calcium pump with GFP identifies roles for intracellular calcium in controlling cell sorting during morphogenesis in Dictyostelium. Dev Biol. 1998 Apr 01; 196(1):77-94. Cubitt AB, Reddy I, Lee S, McNally JG, Firtel RA. PMID: 9527882.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    94. The homeobox-containing gene Wariai regulates anterior-posterior patterning and cell-type homeostasis in Dictyostelium. Development. 1998 Jan; 125(2):313-25. Han Z, Firtel RA. PMID: 9486804.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    95. A ubiquitin-conjugating enzyme is essential for developmental transitions in Dictyostelium. Mol Biol Cell. 1997 Oct; 8(10):1989-2002. Clark A, Nomura A, Mohanty S, Firtel RA. PMID: 9348538; PMCID: PMC25659.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    96. Activation of the mitogen-activated protein kinase ERK2 by the chemoattractant folic acid in Dictyostelium. J Biol Chem. 1997 Sep 19; 272(38):23690-5. Maeda M, Firtel RA. PMID: 9295311.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    97. The Dictyostelium MAP kinase kinase DdMEK1 regulates chemotaxis and is essential for chemoattractant-mediated activation of guanylyl cyclase. EMBO J. 1997 Jul 16; 16(14):4317-32. Ma H, Gamper M, Parent C, Firtel RA. PMID: 9250676; PMCID: PMC1170058.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    98. Inactivation of two Dictyostelium discoideum genes, DdPIK1 and DdPIK2, encoding proteins related to mammalian phosphatidylinositide 3-kinases, results in defects in endocytosis, lysosome to postlysosome transport, and actin cytoskeleton organization. J Cell Biol. 1997 Mar 24; 136(6):1271-86. Buczynski G, Grove B, Nomura A, Kleve M, Bush J, Firtel RA, Cardelli J. PMID: 9087443; PMCID: PMC2132510.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    99. Role of cAMP-dependent protein kinase in controlling aggregation and postaggregative development in Dictyostelium. Dev Biol. 1997 Mar 15; 183(2):208-21. Mann SK, Brown JM, Briscoe C, Parent C, Pitt G, Devreotes PN, Firtel RA. PMID: 9126295.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    100. A Ras GAP is essential for cytokinesis and spatial patterning in Dictyostelium. Development. 1997 Mar; 124(5):983-96. Lee S, Escalante R, Firtel RA. PMID: 9056774.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    101. The Dictyostelium mitogen-activated protein kinase ERK2 is regulated by Ras and cAMP-dependent protein kinase (PKA) and mediates PKA function. J Biol Chem. 1997 Feb 14; 272(7):3883-6. Aubry L, Maeda M, Insall R, Devreotes PN, Firtel RA. PMID: 9020088.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    102. Analysis of cell movement and signalling during ring formation in an activated G alpha1 mutant of Dictyostelium discoideum that is defective in prestalk zone formation. Dev Biol. 1997 Jan 01; 181(1):79-90. Rietdorf J, Siegert F, Dharmawardhane S, Firtel RA, Weijer CJ. PMID: 9015266.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    103. Interacting signaling pathways controlling multicellular development in Dictyostelium. Curr Opin Genet Dev. 1996 Oct; 6(5):545-54. Firtel RA. PMID: 8939724.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    104. Multiple roles of the novel protein tyrosine phosphatase PTP3 during Dictyostelium growth and development. Mol Cell Biol. 1996 May; 16(5):2431-44. Gamper M, Howard PK, Hunter T, Firtel RA. PMID: 8628311; PMCID: PMC231232.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    105. Mutations in the Dictyostelium heterotrimeric G protein alpha subunit G alpha5 alter the kinetics of tip morphogenesis. Development. 1996 Apr; 122(4):1215-24. Hadwiger JA, Natarajan K, Firtel RA. PMID: 8620848.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    106. Seven helix chemoattractant receptors transiently stimulate mitogen-activated protein kinase in Dictyostelium. Role of heterotrimeric G proteins. J Biol Chem. 1996 Feb 16; 271(7):3351-4. Maeda M, Aubry L, Insall R, Gaskins C, Devreotes PN, Firtel RA. PMID: 8631932.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    107. The Dictyostelium MAP kinase ERK2 regulates multiple, independent developmental pathways. Genes Dev. 1996 Jan 01; 10(1):118-28. Gaskins C, Clark AM, Aubry L, Segall JE, Firtel RA. PMID: 8557190.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    108. A phosphatidylinositol (PI) kinase gene family in Dictyostelium discoideum: biological roles of putative mammalian p110 and yeast Vps34p PI 3-kinase homologs during growth and development. Mol Cell Biol. 1995 Oct; 15(10):5645-56. Zhou K, Takegawa K, Emr SD, Firtel RA. PMID: 7565716; PMCID: PMC230815.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    109. Patterns of free calcium in multicellular stages of Dictyostelium expressing jellyfish apoaequorin. Development. 1995 Aug; 121(8):2291-301. Cubitt AB, Firtel RA, Fischer G, Jaffe LF, Miller AL. PMID: 7671796.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    110. Integration of signaling information in controlling cell-fate decisions in Dictyostelium. Genes Dev. 1995 Jun 15; 9(12):1427-44. Firtel RA. PMID: 7601348.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    111. Serpentine cAMP receptors may act through a G protein-independent pathway to induce postaggregative development in Dictyostelium. Cell. 1995 Jun 02; 81(5):737-45. Schnitzler GR, Briscoe C, Brown JM, Firtel RA. PMID: 7774015.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    112. Intercellular signaling. A kinase for cell-fate determination? Curr Biol. 1995 Mar 01; 5(3):228-31. Briscoe C, Firtel RA. PMID: 7780726.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    113. Growth and developmental functions of a human immunodeficiency virus Tat-binding protein/26S protease subunit homolog from Dictyostelium discoideum. Mol Cell Biol. 1995 Mar; 15(3):1725-36. Cao JG, Firtel RA. PMID: 7862164; PMCID: PMC230397.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    114. A MAP kinase necessary for receptor-mediated activation of adenylyl cyclase in Dictyostelium. J Cell Biol. 1995 Feb; 128(3):405-13. Segall JE, Kuspa A, Shaulsky G, Ecke M, Maeda M, Gaskins C, Firtel RA, Loomis WF. PMID: 7844154; PMCID: PMC2120359.
      View in: PubMed   Mentions: 67     Fields:    Translation:AnimalsCells
    115. Regulatory role of the G alpha 1 subunit in controlling cellular morphogenesis in Dictyostelium. Development. 1994 Dec; 120(12):3549-61. Dharmawardhane S, Cubitt AB, Clark AM, Firtel RA. PMID: 7821221.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    116. Identification and characterization of multiple A/T-rich cis-acting elements that control expression from Dictyostelium actin promoters: the Dictyostelium actin upstream activating sequence confers growth phase expression and has enhancer-like properties. Nucleic Acids Res. 1994 Nov 25; 22(23):5099-111. Hori R, Firtel RA. PMID: 7800506; PMCID: PMC523784.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    117. Expression of cAMP-dependent protein kinase in prespore cells is sufficient to induce spore cell differentiation in Dictyostelium. Proc Natl Acad Sci U S A. 1994 Oct 25; 91(22):10561-5. Mann SK, Richardson DL, Lee S, Kimmel AR, Firtel RA. PMID: 7937993; PMCID: PMC45061.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    118. The G alpha subunit G alpha 4 couples to pterin receptors and identifies a signaling pathway that is essential for multicellular development in Dictyostelium. Proc Natl Acad Sci U S A. 1994 Oct 25; 91(22):10566-70. Hadwiger JA, Lee S, Firtel RA. PMID: 7937994; PMCID: PMC45062.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    119. Identification and functional analysis of a developmentally regulated extracellular signal-regulated kinase gene in Dictyostelium discoideum. Mol Cell Biol. 1994 Oct; 14(10):6996-7012. Gaskins C, Maeda M, Firtel RA. PMID: 7935416; PMCID: PMC359230.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    120. A GBF-binding site and a novel AT element define the minimal sequences sufficient to direct prespore-specific expression in Dictyostelium discoideum. Mol Cell Biol. 1994 Sep; 14(9):5840-9. Powell-Coffman JA, Schnitzler GR, Firtel RA. PMID: 8065317; PMCID: PMC359110.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    121. Regulation by protein-tyrosine phosphatase PTP2 is distinct from that by PTP1 during Dictyostelium growth and development. Mol Cell Biol. 1994 Aug; 14(8):5154-64. Howard PK, Gamper M, Hunter T, Firtel RA. PMID: 7518559; PMCID: PMC359034.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    122. Characterization of a novel Dictyostelium discoideum prespore-specific gene, PspB, reveals conserved regulatory sequences. Development. 1994 Jun; 120(6):1601-11. Powell-Coffman JA, Firtel RA. PMID: 8050366.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    123. Cloning and targeted mutations of G alpha 7 and G alpha 8, two developmentally regulated G protein alpha-subunit genes in Dictyostelium. Mol Biol Cell. 1994 Jun; 5(6):691-702. Wu L, Gaskins C, Zhou K, Firtel RA, Devreotes PN. PMID: 7949425; PMCID: PMC301084.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    124. LagC is required for cell-cell interactions that are essential for cell-type differentiation in Dictyostelium. Genes Dev. 1994 Apr 15; 8(8):948-58. Dynes JL, Clark AM, Shaulsky G, Kuspa A, Loomis WF, Firtel RA. PMID: 7926779.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    125. Cloning and characterization of the G-box binding factor, an essential component of the developmental switch between early and late development in Dictyostelium. Genes Dev. 1994 Feb 15; 8(4):502-14. Schnitzler GR, Fischer WH, Firtel RA. PMID: 8125261.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    126. Spatial and temporal expression of the Dictyostelium discoideum G alpha protein subunit G alpha 2: expression of a dominant negative protein inhibits proper prestalk to stalk differentiation. Mol Biol Cell. 1994 Jan; 5(1):7-16. Carrel F, Dharmawardhane S, Clark AM, Powell-Coffman JA, Firtel RA. PMID: 8186466; PMCID: PMC301005.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    127. Characterization of the signal transduction pathways and cis-acting DNA sequence responsible for the transcriptional induction during growth and development of the lysosomal alpha-mannosidase gene in Dictyostelium discoideum. J Biol Chem. 1993 Sep 15; 268(26):19632-9. Schatzle J, Bush J, Dharmawardhane S, Firtel RA, Gomer RH, Cardelli J. PMID: 8366107.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    128. cAMP-dependent protein kinase differentially regulates prestalk and prespore differentiation during Dictyostelium development. Development. 1993 Sep; 119(1):135-46. Mann SK, Firtel RA. PMID: 8275851.
      View in: PubMed   Mentions: 26     Fields:    Translation:Animals
    129. Developmentally regulated changes in 1,2-diacylglycerol in Dictyostelium. Regulation by light and G proteins. J Biol Chem. 1993 Aug 15; 268(23):17431-9. Cubitt AB, Dharmawardhane S, Firtel RA. PMID: 8394342.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    130. Cell-permeable non-hydrolyzable cAMP derivatives as tools for analysis of signaling pathways controlling gene regulation in Dictyostelium. J Biol Chem. 1993 Mar 25; 268(9):6323-31. Schaap P, van Ments-Cohen M, Soede RD, Brandt R, Firtel RA, Dostmann W, Genieser HG, Jastorff B, van Haastert PJ. PMID: 8384208.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    131. Tyrosine phosphorylation of actin in Dictyostelium associated with cell-shape changes. Science. 1993 Jan 08; 259(5092):241-4. Howard PK, Sefton BM, Firtel RA. PMID: 7678470.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    132. Molecular cloning of casein kinase II alpha subunit from Dictyostelium discoideum and its expression in the life cycle. Mol Cell Biol. 1992 Dec; 12(12):5711-23. Kikkawa U, Mann SK, Firtel RA, Hunter T. PMID: 1448100; PMCID: PMC360511.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    133. DdPK3, which plays essential roles during Dictyostelium development, encodes the catalytic subunit of cAMP-dependent protein kinase. Proc Natl Acad Sci U S A. 1992 Nov 15; 89(22):10701-5. Mann SK, Yonemoto WM, Taylor SS, Firtel RA. PMID: 1332055; PMCID: PMC50409.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    134. Analysis of a spatially regulated phosphotyrosine phosphatase identifies tyrosine phosphorylation as a key regulatory pathway in Dictyostelium. Cell. 1992 Nov 13; 71(4):637-47. Howard PK, Sefton BM, Firtel RA. PMID: 1423620.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    135. Amino acid substitutions in the Dictyostelium G alpha subunit G alpha 2 produce dominant negative phenotypes and inhibit the activation of adenylyl cyclase, guanylyl cyclase, and phospholipase C. Mol Biol Cell. 1992 Jul; 3(7):735-47. Okaichi K, Cubitt AB, Pitt GS, Firtel RA. PMID: 1355376; PMCID: PMC275631.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    136. A G-rich sequence element common to Dictyostelium genes which differ radically in their patterns of expression. Dev Biol. 1992 Jul; 152(1):188-93. Ceccarelli A, Mahbubani HJ, Insall R, Schnitzler G, Firtel RA, Williams JG. PMID: 1321061.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    137. A negative transcriptional control region of a developmentally-regulated gene co-localizes with the origin of replication of an endogenous plasmid in Dictyostelium. Nucleic Acids Res. 1992 Jun 11; 20(11):2795-802. Powell JA, Galindo J, Firtel RA. PMID: 1319575; PMCID: PMC336924.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    138. Characterization of phospholipase activity in Dictyostelium discoideum. Identification of a Ca(2+)-dependent polyphosphoinositide-specific phospholipase C. Biochem J. 1992 Apr 15; 283 ( Pt 2):371-8. Cubitt AB, Firtel RA. PMID: 1315514; PMCID: PMC1131043.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    139. Regulation of the Dictyostelium cAMP-induced, prestalk-specific DdrasD gene: identification of cis-acting elements. Nucleic Acids Res. 1992 Mar 25; 20(6):1325-32. Esch RK, Howard PK, Firtel RA. PMID: 1313967; PMCID: PMC312178.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    140. The Myb DNA-binding domain is highly conserved in Dictyostelium discoideum. Oncogene. 1992 Mar; 7(3):589-96. Stober-Grässer U, Brydolf B, Bin X, Grässer F, Firtel RA, Lipsick JS. PMID: 1549373.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    141. Molecular genetic analysis of signal transduction pathways controlling multicellular development in Dictyostelium. Cold Spring Harb Symp Quant Biol. 1992; 57:177-92. Cubitt AB, Carrel F, Dharmawardhane S, Gaskins C, Hadwiger J, Howard P, Mann SK, Okaichi K, Zhou K, Firtel RA. PMID: 1339658.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    142. Analysis of G alpha 4, a G-protein subunit required for multicellular development in Dictyostelium. Genes Dev. 1992 Jan; 6(1):38-49. Hadwiger JA, Firtel RA. PMID: 1730409.
      View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
    143. Developmental and spatial regulation of a Dictyostelium prespore gene: cis-acting elements and a cAMP-induced, developmentally regulated DNA binding activity. Development. 1991 Nov; 113(3):947-58. Haberstroh L, Galindo J, Firtel RA. PMID: 1668278.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    144. Signal transduction pathways controlling multicellular development in Dictyostelium. Trends Genet. 1991 Nov-Dec; 7(11-12):381-8. Firtel RA. PMID: 1668191.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    145. cAMP signal transduction pathways regulating development of Dictyostelium discoideum. Curr Opin Genet Dev. 1991 Oct; 1(3):383-90. Kimmel AR, Firtel RA. PMID: 1668648.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    146. Identification of Dictyostelium G alpha genes expressed during multicellular development. Proc Natl Acad Sci U S A. 1991 Sep 15; 88(18):8213-7. Hadwiger JA, Wilkie TM, Strathmann M, Firtel RA. PMID: 1910174; PMCID: PMC52477.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    147. A developmentally regulated, putative serine/threonine protein kinase is essential for development in Dictyostelium. Mech Dev. 1991 Sep; 35(2):89-101. Mann SK, Firtel RA. PMID: 1836954.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    148. A secreted 80 x 10(3) Mr protein mediates sensing of cell density and the onset of development in Dictyostelium. Development. 1991 May; 112(1):269-78. Gomer RH, Yuen IS, Firtel RA. PMID: 1663029.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    149. Putting the G in development. Curr Biol. 1991 Apr; 1(2):91-3. Firtel RA. PMID: 15336175.
      View in: PubMed   Mentions:    Fields:    
    150. Molecular genetic analysis of two G alpha protein subunits in Dictyostelium. J Biol Chem. 1991 Jan 15; 266(2):1220-8. Kumagai A, Hadwiger JA, Pupillo M, Firtel RA. PMID: 1670774.
      View in: PubMed   Mentions: 57     Fields:    Translation:AnimalsCells
    151. cAMP and cell sorting control the spatial expression of a developmentally essential cell-type-specific ras gene in Dictyostelium. Genes Dev. 1991 Jan; 5(1):9-21. Esch RK, Firtel RA. PMID: 1703508.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    152. A spatial gradient of expression of a cAMP-regulated prespore cell-type-specific gene in Dictyostelium. Genes Dev. 1990 Apr; 4(4):596-612. Haberstroh L, Firtel RA. PMID: 2163344.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    153. A developmentally regulated trans-acting factor recognizes dissimilar G/C-rich elements controlling a class of cAMP-inducible Dictyostelium genes. Genes Dev. 1990 Mar; 4(3):419-32. Hjorth AL, Pears C, Williams JG, Firtel RA. PMID: 2159939.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    154. A role for cAMP-dependent protein kinase A in early Dictyostelium development. Genes Dev. 1990 Jan; 4(1):18-28. Firtel RA, Chapman AL. PMID: 1968413.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    155. Cytokinin oxidase activity in the cellular slime mold, Dictyostelium discoideum. Dev Biol. 1989 Dec; 136(2):491-9. Armstrong DJ, Firtel RA. PMID: 2555236.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    156. Molecular complementation of a genetic marker in Dictyostelium using a genomic DNA library. Proc Natl Acad Sci U S A. 1989 Oct; 86(20):7966-70. Dynes JL, Firtel RA. PMID: 2813371; PMCID: PMC298193.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    157. G protein linked signal transduction pathways in development: dictyostelium as an experimental system. Cell. 1989 Jul 28; 58(2):235-9. Firtel RA, van Haastert PJ, Kimmel AR, Devreotes PN. PMID: 2546676.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    158. Multiple alpha subunits of guanine nucleotide-binding proteins in Dictyostelium. Proc Natl Acad Sci U S A. 1989 Jul; 86(13):4892-6. Pupillo M, Kumagai A, Pitt GS, Firtel RA, Devreotes PN. PMID: 2500658; PMCID: PMC297521.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    159. A trans-acting factor required for cAMP-induced gene expression in Dictyostelium is regulated developmentally and induced by cAMP. Genes Dev. 1989 Jun; 3(6):747-59. Hjorth AL, Khanna NC, Firtel RA. PMID: 2545528.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    160. Regulation and function of G alpha protein subunits in Dictyostelium. Cell. 1989 Apr 21; 57(2):265-75. Kumagai A, Pupillo M, Gundersen R, Miake-Lye R, Devreotes PN, Firtel RA. PMID: 2539262.
      View in: PubMed   Mentions: 72     Fields:    Translation:Animals
    161. Two-phase regulatory pathway controls cAMP receptor-mediated expression of early genes in Dictyostelium. Proc Natl Acad Sci U S A. 1989 Mar; 86(6):1924-8. Mann SK, Firtel RA. PMID: 2538821; PMCID: PMC286817.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    162. Cyclic-AMP-induced elevation of intracellular pH precedes, but does not mediate, the induction of prespore differentiation in Dictyostelium discoideum. Development. 1989 Feb; 105(2):401-6. Van Lookeren Campagne MM, Aerts RJ, Spek W, Firtel RA, Schaap P. PMID: 2553386.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    163. Molecular analysis of a developmentally regulated gene required for Dictyostelium aggregation. Dev Biol. 1989 Jan; 131(1):27-36. Rubino S, Mann SK, Hori RT, Pinko C, Firtel RA. PMID: 2909407.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    164. cAMP regulation of early gene expression in signal transduction mutants of Dictyostelium. Dev Biol. 1988 Nov; 130(1):294-303. Mann SK, Pinko C, Firtel RA. PMID: 2846388.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    165. Regulation of Dictyostelium early gene expression in cAMP bypass mutants. Dev Biol. 1988 Nov; 130(1):406-10. Mann SK, Pinko C, Firtel RA. PMID: 2846389.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    166. Identification of regions essential for extrachromosomal replication and maintenance of an endogenous plasmid in Dictyostelium. Nucleic Acids Res. 1988 Jul 25; 16(14B):6825-37. Ahern KG, Howard PK, Firtel RA. PMID: 3405751; PMCID: PMC338336.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    167. Establishment of a transient expression system for Dictyostelium discoideum. Nucleic Acids Res. 1988 Mar 25; 16(6):2613-23. Howard PK, Ahern KG, Firtel RA. PMID: 3362676; PMCID: PMC336393.
      View in: PubMed   Mentions: 69     Fields:    Translation:AnimalsCells
    168. An 80-bp cis-acting regulatory region controls cAMP and development regulation of a prestalk gene in Dictyostelium. Genes Dev. 1988 Mar; 2(3):294-304. Datta S, Firtel RA. PMID: 2897942.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    169. cAMP receptor and G-protein interactions control development in Dictyostelium. Cold Spring Harb Symp Quant Biol. 1988; 53 Pt 2:657-65. Pupillo M, Klein P, Vaughan R, Pitt G, Lilly P, Sun T, Devreotes P, Kumagai A, Firtel R. PMID: 3151181.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    170. A molecular analysis of G proteins and control of early gene expression by the cell-surface cAMP receptor in Dictyostelium. Cold Spring Harb Symp Quant Biol. 1988; 53 Pt 2:675-85. Kumagai A, Mann SK, Pupillo M, Pitt G, Devreotes PN, Firtel RA. PMID: 3151182.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    171. Analysis of cis and trans elements involved in cAMP-inducible gene expression in Dictyostelium discoideum. Dev Genet. 1988; 9(4-5):435-54. Hjorth A, Datta S, Khanna NC, Firtel RA. PMID: 2907423.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    172. Control of early gene expression in Dictyostelium. Dev Genet. 1988; 9(4-5):337-50. Mann SK, Pinko C, Firtel RA. PMID: 2854022.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    173. Mutant ras gene induces elevated levels of inositol tris- and hexakisphosphates in Dictyostelium. J Cell Sci. 1988 Jan; 89 ( Pt 1):13-20. Europe-Finner GN, Ludérus ME, Small NV, Van Driel R, Reymond CD, Firtel RA, Newell PC. PMID: 2843553.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    174. Cell-autonomous determination of cell-type choice in Dictyostelium development by cell-cycle phase. Science. 1987 Aug 14; 237(4816):758-62. Gomer RH, Firtel RA. PMID: 3039657.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    175. Aberrant transmembrane signal transduction in Dictyostelium cells expressing a mutated ras gene. Proc Natl Acad Sci U S A. 1987 Jul; 84(14):4905-9. Van Haastert PJ, Kesbeke F, Reymond CD, Firtel RA, Luderus E, Van Driel R. PMID: 2885843; PMCID: PMC305215.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    176. Gene regulation during dedifferentiation in Dictyostelium discoideum. Dev Biol. 1987 Apr; 120(2):561-76. Finney R, Ellis M, Langtimm C, Rosen E, Firtel R, Soll DR. PMID: 3030859.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    177. Cyclic AMP regulation of early gene expression in Dictyostelium discoideum: mediation via the cell surface cyclic AMP receptor. Mol Cell Biol. 1987 Jan; 7(1):458-69. Mann SK, Firtel RA. PMID: 3031475; PMCID: PMC365089.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    178. Identification of the sequences controlling cyclic AMP regulation and cell-type-specific expression of a prestalk-specific gene in Dictyostelium discoideum. Mol Cell Biol. 1987 Jan; 7(1):149-59. Datta S, Firtel RA. PMID: 3031453; PMCID: PMC365051.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    179. Molecular biology in Dictyostelium: tools and applications. Methods Cell Biol. 1987; 28:67-100. Nellen W, Datta S, Reymond C, Sivertsen A, Mann S, Crowley T, Firtel RA. PMID: 3600419.
      View in: PubMed   Mentions: 76     Fields:    Translation:AnimalsCells
    180. Regulatory sequences in the promoter of the Dictyostelium Actin 6 gene. EMBO J. 1986 Dec 01; 5(12):3367-72. Nellen W, Silan C, Saur U, Firtel RA. PMID: 3816763; PMCID: PMC1167335.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    181. Cellular and subcellular distribution of a cAMP-regulated prestalk protein and prespore protein in Dictyostelium discoideum: a study on the ontogeny of prestalk and prespore cells. J Cell Biol. 1986 Nov; 103(5):1999-2015. Gomer RH, Datta S, Firtel RA. PMID: 3023394; PMCID: PMC2114392.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    182. cAMP induction of prespore and prestalk gene expression in Dictyostelium is mediated by the cell-surface cAMP receptor. Proc Natl Acad Sci U S A. 1986 Nov; 83(22):8624-8. Gomer RH, Armstrong D, Leichtling BH, Firtel RA. PMID: 3022299; PMCID: PMC386983.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    183. Phenotypic changes induced by a mutated ras gene during the development of Dictyostelium transformants. Nature. 1986 Sep 25-Oct 1; 323(6086):340-3. Reymond CD, Gomer RH, Nellen W, Theibert A, Devreotes P, Firtel RA. PMID: 3093890.
      View in: PubMed   Mentions: 39     Fields:    Translation:Animals
    184. Analysis of gene expression in rapidly developing mutants of Dictyostelium discoideum. Dev Biol. 1986 Jun; 115(2):407-14. Saxe CL, Firtel RA. PMID: 2423400.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    185. Spatial and temporal regulation of a foreign gene by a prestalk-specific promoter in transformed Dictyostelium discoideum. Mol Cell Biol. 1986 Mar; 6(3):811-20. Datta S, Gomer RH, Firtel RA. PMID: 3022131; PMCID: PMC367581.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    186. The use of restriction fragment length polymorphisms and DNA duplications to study the organization of the actin multigene family in Dictyostelium discoideum. Genetics. 1986 Jan; 112(1):27-42. Welker DL, Hirth KP, Romans P, Noegel A, Firtel RA, Williams KL. PMID: 3002908; PMCID: PMC1202689.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    187. Regulation of the Dictyostelium ras gene during development and in transformants. Prog Clin Biol Res. 1986; 217A:17-21. Reymond CD, Nellen W, Gomer RH, Firtel RA. PMID: 3749127.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    188. Regulation of late gene expression in a temperature-sensitive cohesion-defective mutant of Dictyostelium discoideum. Dev Genet. 1986; 7(2):99-108. Saxe CL, Firtel RA. PMID: 3453780.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    189. Phenocopy of discoidin I-minus mutants by antisense transformation in Dictyostelium. Cell. 1985 Dec; 43(3 Pt 2):633-41. Crowley TE, Nellen W, Gomer RH, Firtel RA. PMID: 4075402.
      View in: PubMed   Mentions: 84     Fields:    Translation:Animals
    190. Gene-specific expression of the actin multigene family of Dictyostelium discoideum. J Mol Biol. 1985 Nov 20; 186(2):337-55. Romans P, Firtel RA, Saxe CL. PMID: 4087297.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    191. Organization of the actin multigene family of Dictyostelium discoideum and analysis of variability in the protein coding regions. J Mol Biol. 1985 Nov 20; 186(2):321-35. Romans P, Firtel RA. PMID: 3003365.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    192. Extrachromosomal replication of shuttle vectors in Dictyostelium discoideum. Mol Cell Biol. 1985 Nov; 5(11):3241-50. Firtel RA, Silan C, Ward TE, Howard P, Metz BA, Nellen W, Jacobson A. PMID: 3018510; PMCID: PMC369140.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    193. Regulated expression of ras gene constructs in Dictyostelium transformants. Proc Natl Acad Sci U S A. 1985 Oct; 82(20):7005-9. Reymond CD, Nellen W, Firtel RA. PMID: 3863137; PMCID: PMC391298.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    194. Sequence organization and developmental expression of an interspersed, repetitive element and associated single-copy DNA sequences in Dictyostelium discoideum. Mol Cell Biol. 1985 Aug; 5(8):2123-30. Kimmel AR, Firtel RA. PMID: 2427932; PMCID: PMC366930.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    195. Organization of the Dictyostelium discoideum actin multigene family. Flanking sequences show subfamily homologies and unusual dyad symmetries. J Mol Biol. 1985 Jun 05; 183(3):311-26. Romans P, Firtel RA. PMID: 2991530.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    196. A secreted factor and cyclic AMP jointly regulate cell-type-specific gene expression in Dictyostelium discoideum. Mol Cell Biol. 1985 Apr; 5(4):705-13. Mehdy MC, Firtel RA. PMID: 2985966; PMCID: PMC366773.
      View in: PubMed   Mentions: 49     Fields:    Translation:Animals
    197. Regulation of cell-type-specific gene expression in Dictyostelium. Cold Spring Harb Symp Quant Biol. 1985; 50:801-12. Gomer RH, Datta S, Mehdy M, Crowley T, Sivertsen A, Nellen W, Reymond C, Mann S, Firtel RA. PMID: 3868507.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    198. High-copy-number transformants and co-transformation in Dictyostelium. Gene. 1985; 39(2-3):155-63. Nellen W, Firtel RA. PMID: 4092928.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    199. DNA-mediated transformation in Dictyostelium discoideum: regulated expression of an actin gene fusion. Mol Cell Biol. 1984 Dec; 4(12):2890-8. Nellen W, Silan C, Firtel RA. PMID: 6098825; PMCID: PMC369302.
      View in: PubMed   Mentions: 95     Fields:    Translation:Animals
    200. Site-specific phasing in the chromatin of the rDNA in Dictyostelium discoideum. J Mol Biol. 1984 Nov 25; 180(1):73-90. Edwards CA, Firtel RA. PMID: 6595421.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    201. Developmental regulation of a Dictyostelium gene encoding a protein homologous to mammalian ras protein. Cell. 1984 Nov; 39(1):141-8. Reymond CD, Gomer RH, Mehdy MC, Firtel RA. PMID: 6091907.
      View in: PubMed   Mentions: 92     Fields:    Translation:AnimalsCells
    202. Genomic instability and mobile genetic elements in regions surrounding two discoidin I genes of Dictyostelium discoideum. Mol Cell Biol. 1984 Apr; 4(4):671-80. Poole SJ, Firtel RA. PMID: 6325889; PMCID: PMC368779.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    203. Conserved structural features are found upstream from the three co-ordinately regulated discoidin I genes of Dictyostelium discoideum. J Mol Biol. 1984 Jan 15; 172(2):203-20. Poole SJ, Firtel RA. PMID: 6694210.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    204. An unusual transposon encoding heat shock inducible and developmentally regulated transcripts in Dictyostelium. Cell. 1983 Nov; 35(1):243-51. Rosen E, Sivertsen A, Firtel RA. PMID: 6194899.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    205. Induction and modulation of cell-type-specific gene expression in Dictyostelium. Cell. 1983 Mar; 32(3):763-71. Mehdy MC, Ratner D, Firtel RA. PMID: 6299575.
      View in: PubMed   Mentions: 82     Fields:    Translation:Animals
    206. Sequence organization in Dictyostelium: unique structure at the 5'-ends of protein coding genes. Nucleic Acids Res. 1983 Jan 25; 11(2):541-52. Kimmel AR, Firtel RA. PMID: 6828377; PMCID: PMC325732.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    207. A DNA-mediated transformation system for Dictyostelium discoideum. Proc Natl Acad Sci U S A. 1982 Dec; 79(23):7356-60. Hirth KP, Edwards CA, Firtel RA. PMID: 6296830; PMCID: PMC347338.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    208. Actin multigene family of Dictyostelium. Cold Spring Harb Symp Quant Biol. 1982; 46 Pt 2:495-505. McKeown M, Firtel RA. PMID: 6286214.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    209. Examination of the regulation of the actin multigene family in Dictyostelium discoideum. Prog Clin Biol Res. 1982; 85 Pt A:51-78. McKeown M, Hirth KP, Edwards C, Firtel RA. PMID: 7051026.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    210. Sequence and expression of the discoidin I gene family in Dictyostelium discoideum. J Mol Biol. 1981 Dec 05; 153(2):273-89. Poole S, Firtel RA, Lamar E, Rowekamp W. PMID: 6279874.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    211. Evidence for sub-families of actin genes in Dictyostelium as determined by comparisons of 3' end sequences. J Mol Biol. 1981 Oct 05; 151(4):593-606. McKeown M, Firtel RA. PMID: 6276562.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    212. Differential expression and 5' end mapping of actin genes in Dictyostelium. Cell. 1981 Jun; 24(3):799-807. McKeown M, Firtel RA. PMID: 6894715.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    213. Multigene families encoding actin and tubulin. Cell. 1981 Apr; 24(1):6-7. Firtel RA. PMID: 6894564.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    214. Intervening sequences in a Dictyostelium gene that encodes a low abundance class mRNA. Nucleic Acids Res. 1980 Dec 11; 8(23):5599-610. Kimmel AR, Firtel RA. PMID: 7465423; PMCID: PMC324328.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    215. Isolation of developmentally regulated genes from Dictyostelium. Dev Biol. 1980 Oct; 79(2):409-18. Rowekamp W, Firtel RA. PMID: 7429011.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    216. Analysis of the multigene family coding the developmentally regulated carbohydrate-binding protein discoidin-I in D. discoideum. Cell. 1980 Jun; 20(2):495-505. Rowekamp W, Poole S, Firtel RA. PMID: 7388948.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    217. Regulation of actin gene expression during spore germination in Dictyostelium discoideum. Dev Biol. 1980 May; 76(2):263-74. MacLeod C, Firtel RA, Papkoff J. PMID: 6893032.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    218. Unusual nucleotide sequences at the 5' end of actin genes in Dictyostelium discoideum. Proc Natl Acad Sci U S A. 1979 Dec; 76(12):6206-10. Firtel RA, Timm R, Kimmel AR, McKeown M. PMID: 293714; PMCID: PMC411832.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    219. Evidence that populations of Dictyostelium single-copy mRNA transcripts carry common repeat sequences. Nucleic Acids Res. 1979 Jun 11; 6(7):2403-22. Kindle KL, Firtel RA. PMID: 461193; PMCID: PMC327862.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    220. A family of short, interspersed repeat sequences at the 5' end of a set of Dictyostelium single-copy mRNAs. Cell. 1979 Apr; 16(4):787-96. Kimmel AR, Firtel RA. PMID: 455448.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    221. Dictyostelium rDNA consists of non-chromosomal palindromic dimers containing 5S and 36S coding regions. Chromosoma. 1978 Dec 21; 70(1):19-29. Cockburn AF, Taylor WC, Firtel RA. PMID: 738167.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    222. Multiple, heterogeneous actin genes in Dictyostelium. Cell. 1978 Nov; 15(3):789-800. McKeown M, Taylor WC, Kindle KL, Firtel RA, Bender W, Davidson N. PMID: 728991.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    223. Identification and analysis of Dictyostelium actin genes, a family of moderately repeated genes. Cell. 1978 Nov; 15(3):763-78. Kindle KL, Firtel RA. PMID: 728989.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    224. The structure of M6, a recombinant plasmid containing Dictyostelium DNA homologous to actin messenger RNA. Cell. 1978 Nov; 15(3):779-88. Bender W, Davidson N, Kindle KL, Taylor WC, Silverman M, Firtel RA. PMID: 728990.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    225. Regulation of the synthesis of two carbohydrate-binding proteins in Dictyostelium discoideum. J Biol Chem. 1978 Jun 10; 253(11):3924-32. Ma GC, Firtel RA. PMID: 565775.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    226. Organization of the ribosomal RNA genes of Dictyostelium discoideum. Mapping of the transcribed region. J Mol Biol. 1977 Feb 05; 109(4):539-58. Frankel G, Cockburn AF, Kindle KL, Firtel RA. PMID: 557566.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    227. Organization of the ribosomal RNA genes of Dictyostelium discoideum: mapping of the nontranscribed spacer regions. Cell. 1976 Dec; 9(4 Pt 1):605-13. Cockburn AF, Newkirk MJ, Firtel RA. PMID: 1034500.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    228. Structural organization of the genome of Dictyostelium discoideum: analysis by EcoR1 restriction endonuclease. J Mol Biol. 1976 Apr 25; 102(4):831-52. Firtel RA, Cockburn A, Frankel G, Hershfield V. PMID: 781265.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    229. Developmentally regulated proteins of the plasma membrane of Dictyostelium discoideum. The carbohydrate-binding protein. J Mol Biol. 1976 Jan 15; 100(2):157-78. Siu CH, Lerner RA, Ma G, Firtel RA, Loomis WF. PMID: 815552.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    230. Structural organization and processing of the genetic transcript in the cellular slime mold Dictyostelium discoideum. Fed Proc. 1976 Jan; 35(1):13-22. Firtel RA, Kindle K, Huxley MP. PMID: 942701.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    231. Structural organization of the genome of the cellular slime mold Dictyostelium discoideum: interspersion of repetitive and single-copy DNA sequences. Cell. 1975 Aug; 5(4):401-11. Firtel RA, Kindle K. PMID: 1171729.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    232. The synthesis of messenger RNA in the cellular slime mold Dictyosteilum discoideum. Brookhaven Symp Biol. 1975 Jul; (26):307-19. Jacobson A, Firtel R, Lodish HF. PMID: 1238151.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    233. Ribonucleoprotein particles containing heterogeneous nuclear RNA in the cellular slime mold Dictyostelium discoideum. Proc Natl Acad Sci U S A. 1975 Jan; 72(1):301-5. Firtel RA, Pederson T. PMID: 1054507; PMCID: PMC432292.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    234. Synthesis of messenger RNA and chromosome structure in the cellular slime mold. Proc Natl Acad Sci U S A. 1974 Dec; 71(12):5103-8. Lodish HF, Jacobson A, Firtel R, Alton T, Tuchman J. PMID: 4531041; PMCID: PMC434048.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    235. Synthesis of DNA complementary to cellular slime mold messenger RNA by reverse transcriptase. Biochemistry. 1974 Sep 10; 13(19):3917-22. Verma IM, Firtel RA, Lodish HF, Baltimore D. PMID: 4137959.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    236. Gene activity during development of the cellular slime mold Dictyostelium discoideum. Genetics. 1974 Sep; 78(1):355-72. Firtel RA, Jacobson A, Tuchman J, Lodish HF. PMID: 4474971; PMCID: PMC1213196.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    237. The degradation of ribonucleic acids injected into Xenopus laevis oocytes. Cell. 1974 Jul; 2(3):189-96. Allende CC, Allende JE, Firtel RA. PMID: 4370441.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    238. Transcription of polydeoxythymidylate sequences in the genome of the cellular slime mold, Dictyostelium discoideum. Proc Natl Acad Sci U S A. 1974 May; 71(5):1607-11. Jacobson A, Firtel RA, Lodish H. PMID: 4525281; PMCID: PMC388285.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    239. Synthesis of messenger and ribosomal RNA precursors in isolated nuclei of the cellular slime mold Dictyostelium discoideum. J Mol Biol. 1974 Jan 15; 82(2):213-30. Jacobson A, Firtel RA, Lodish HF. PMID: 4856245.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    240. Transcription and structure of the genome of the cellular slime mold Dictyostelium discoideum. Cold Spring Harb Symp Quant Biol. 1974; 38:899-914. Lodish HF, Firtel RA, Jacobson A. PMID: 4524794.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    241. A small nuclear precursor of messenger RNA in the cellular slime mold Dictyostelium discoideum. J Mol Biol. 1973 Sep 15; 79(2):295-314. Firtel RA, Lodish HF. PMID: 4796769.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    242. Actinomycin D and the regulation of enzyme biosynthesis during development of Dictyostelium discoideum. J Mol Biol. 1973 Sep 15; 79(2):315-27. Firtel RA, Baxter L, Lodish HF. PMID: 4796770.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    243. Isolation and hybridization kinetics of messenger RNA from Dictyostelium discoideum. Nat New Biol. 1972 Oct 25; 239(95):225-8. Firtel RA, Jacobson A, Lodish HF. PMID: 4507801.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    244. Developmental control of -1-4 glucan phosphorylase in the cellular slime mold Dictyostelium discoideum. Dev Biol. 1972 Sep; 29(1):85-103. Firtel RA, Bonner J. PMID: 4672568.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    245. Changes in the expression of single-copy DNA during development of the cellular slime mold Dictyostelium discoideum. J Mol Biol. 1972 May 28; 66(3):363-77. Firtel RA. PMID: 5064459.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    246. Characterization of the genome of the cellular slime mold Dictyostelium discoideum. J Mol Biol. 1972 May 28; 66(3):339-61. Firtel RA, Bonner J. PMID: 4556574.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    247. Partial characterization of several protein and amino acid metabolizing enzymes in the cellular slime mold Dictyostelium discoideum. Dev Biol. 1972 Mar; 27(3):307-21. Firtel RA, Brackenbruy RW. PMID: 4623049.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    248. Polysomes and RNA synthesis during early development of the surf clam Spisula solidissima. Dev Biol. 1970 Feb; 21(1):87-104. Firtel RA, Monroy A. PMID: 5445762.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
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