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Steven Plaxe

Title(s)Professor Of Clinical, Reproductive Medicine
SchoolHealth Sciences
Phone858-822-6199
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Dasanu CA, Iskandar AS, Hwang A, Kerr WT, Farrell S, Grover M, Ocampo MM, Lerner J, Plaxe SC. Management and clinical outcomes in uterine malignant mixed Müllerian tumor: Lessons from a single-institution series. J Oncol Pharm Pract. 2019 Aug 31; 1078155219869441. PMID: 31474213.
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    2. Iskandar AS, Kerr WT, Hwang A, Farrell S, Plaxe SC, Dasanu CA. Impact of therapeutic modalities on disease-specific survival in older adults with glioblastoma: A single-institution retrospective cohort study. J Oncol Pharm Pract. 2019 Jun 25; 1078155219857792. PMID: 31238807.
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    3. Charo LM, Plaxe SC. Recent advances in endometrial cancer: a review of key clinical trials from 2015 to 2019. F1000Res. 2019; 8. PMID: 31231511.
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    4. Hwang A, Iskandar AS, Kerr WT, Farrell S, Plaxe SC, Dasanu CA. Clinico-epidemiologic characteristics and patterns of care in Kaposi's sarcoma: Data from a single-institution series. J Oncol Pharm Pract. 2019 Apr 02; 1078155219838614. PMID: 30940048.
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    5. Dasanu CA, Del Rosario M, Codreanu I, Lu Y, Farrell S, Hyams DM, Plaxe SC. Merkel cell carcinoma: long-term follow-up of a single institution series and clinical outcomes by immunological status. Dermatol Online J. 2019 02 15; 25(2). PMID: 30865403.
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    6. Dasanu CA, Plaxe SC, Popescu IM, Gupta V, Sontz E, Codreanu I. Severe left atrial enlargement due to carfilzomib use in multiple myeloma. J Oncol Pharm Pract. 2019 Jan 12; 1078155218825298. PMID: 30636528.
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    7. Dasanu CA, Del Rosario M, Codreanu I, Hyams DM, Plaxe SC. Inferior outcomes in immunocompromised Merkel cell carcinoma patients: Can they be overcome by the use of PD1/PDL1 inhibitors? J Oncol Pharm Pract. 2019 Jan; 25(1):214-216. PMID: 29933728.
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    8. Bean LM, Ward KK, Plaxe SC, McHale MT. Survival of women with microinvasive adenocarcinoma of the cervix is not improved by radical surgery. Am J Obstet Gynecol. 2017 09; 217(3):332.e1-332.e6. PMID: 28522318.
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    9. Dasanu CA, Alvarez-Argote J, Lippman SM, Plaxe SC. Longitudinal thumbnail fissures due to erlotinib therapy for lung cancer. J Oncol Pharm Pract. 2018 04; 24(3):229-231. PMID: 28436313.
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    10. Hillman RT, Saenz CC, McHale MT, Plaxe SC. Fertility preservation and survival among young women with early ovarian cancer living in US counties with gynecologic oncologist services. Int J Gynaecol Obstet. 2017 May; 137(2):157-163. PMID: 28170079.
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    11. Noticewala SS, Li N, Williamson CW, Hoh CK, Shen H, McHale MT, Saenz CC, Einck J, Plaxe S, Vaida F, Yashar CM, Mell LK. Longitudinal Changes in Active Bone Marrow for Cervical Cancer Patients Treated With Concurrent Chemoradiation Therapy. Int J Radiat Oncol Biol Phys. 2017 03 15; 97(4):797-805. PMID: 28244416.
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    12. Mell LK, Sirák I, Wei L, Tarnawski R, Mahantshetty U, Yashar CM, McHale MT, Xu R, Honerkamp-Smith G, Carmona R, Wright M, Williamson CW, Kasaová L, Li N, Kry S, Michalski J, Bosch W, Straube W, Schwarz J, Lowenstein J, Jiang SB, Saenz CC, Plaxe S, Einck J, Khorprasert C, Koonings P, Harrison T, Shi M, Mundt AJ. Bone Marrow-sparing Intensity Modulated Radiation Therapy With Concurrent Cisplatin For Stage IB-IVA Cervical Cancer: An International Multicenter Phase II Clinical Trial (INTERTECC-2). Int J Radiat Oncol Biol Phys. 2017 03 01; 97(3):536-545. PMID: 28126303.
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    13. Taylor KN, McHale MT, Saenz CC, Plaxe SC. Diagnosis and treatment of Clostridium difficile (C. diff) colitis: Review of the literature and a perspective in gynecologic oncology. Gynecol Oncol. 2017 Feb; 144(2):428-437. PMID: 27876339.
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    14. Kurnit KC, Bean LM, Plaxe SC, Saenz CC, McHale MT. Squamous Cell Carcinoma of the Vulva Presenting as an Isolated Inguinal Lymph Node Metastasis: A Case Report. J Reprod Med. 2016 Nov-Dec; 61(11-12):612-14. PMID: 30230291.
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    15. Dasanu CA, Lippman SM, Plaxe SC. Persistently curly hair phenotype with the use of nivolumab for squamous cell lung cancer. J Oncol Pharm Pract. 2017 Dec; 23(8):638-640. PMID: 27824586.
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    16. Morgan RJ, Armstrong DK, Alvarez RD, Bakkum-Gamez JN, Behbakht K, Chen LM, Copeland L, Crispens MA, DeRosa M, Dorigo O, Gershenson DM, Gray HJ, Hakam A, Havrilesky LJ, Johnston C, Lele S, Martin L, Matulonis UA, O'Malley DM, Penson RT, Percac-Lima S, Pineda M, Plaxe SC, Powell MA, Ratner E, Remmenga SW, Rose PG, Sabbatini P, Santoso JT, Werner TL, Burns J, Hughes M. Ovarian Cancer, Version 1.2016, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2016 09; 14(9):1134-63. PMID: 27587625.
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    17. Tierney NM, Saenz C, McHale M, Ward K, Plaxe S. Industry Payments to Obstetrician-Gynecologists: An Analysis of 2014 Open Payments Data. Obstet Gynecol. 2016 Feb; 127(2):376-82. PMID: 26942368.
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    18. Shah NR, Ward KK, Plaxe SC, Saenz CC, McHale MT. Urinary diversions: A time to enrich surgical training? Gynecol Oncol. 2016 Jan; 140(1):120-3. PMID: 26556767.
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    19. Berger AM, Mooney K, Alvarez-Perez A, Breitbart WS, Carpenter KM, Cella D, Cleeland C, Dotan E, Eisenberger MA, Escalante CP, Jacobsen PB, Jankowski C, LeBlanc T, Ligibel JA, Loggers ET, Mandrell B, Murphy BA, Palesh O, Pirl WF, Plaxe SC, Riba MB, Rugo HS, Salvador C, Wagner LI, Wagner-Johnston ND, Zachariah FJ, Bergman MA, Smith C. Cancer-Related Fatigue, Version 2.2015. J Natl Compr Canc Netw. 2015 Aug; 13(8):1012-39. PMID: 26285247.
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    20. Kurnit KC, Ward KK, McHale MT, Saenz CC, Plaxe SC. Increased prevalence of comorbid conditions in women with uterine cancer. Gynecol Oncol. 2015 Sep; 138(3):731-4. PMID: 26160712.
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    21. Bober BG, Gutierrez E, Plaxe S, Groisman A, Shah SB. Combinatorial influences of paclitaxel and strain on axonal transport. Exp Neurol. 2015 Sep; 271:358-67. PMID: 26143110.
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    22. Hillman RT, Ward K, Saenz C, McHale M, Plaxe S. Barriers prevent patient access to personalized therapies identified by molecular tumor profiling of gynecologic malignancies. J Pers Med. 2015 May 21; 5(2):165-73. PMID: 26011384.
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    23. Simpson DR, Scanderbeg DJ, Carmona R, McMurtrie RM, Einck J, Mell LK, McHale MT, Saenz CC, Plaxe SC, Harrison T, Mundt AJ, Yashar CM. Clinical Outcomes of Computed Tomography-Based Volumetric Brachytherapy Planning for Cervical Cancer. Int J Radiat Oncol Biol Phys. 2015 Sep 01; 93(1):150-7. PMID: 26130230.
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    24. Brooks SE, Carter RL, Plaxe SC, Basen-Engquist KM, Rodriguez M, Kauderer J, Walker JL, Myers TK, Drake JG, Havrilesky LJ, Van Le L, Landrum LM, Brown CL. Patient and physician factors associated with participation in cervical and uterine cancer trials: an NRG/GOG247 study. Gynecol Oncol. 2015 Jul; 138(1):101-8. PMID: 25937529.
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    25. Berek JS, Edwards RP, Parker LP, DeMars LR, Herzog TJ, Lentz SS, Morris RT, Akerley WL, Holloway RW, Method MW, Plaxe SC, Walker JL, Friccius-Quecke H, Krasner CN. Catumaxomab for the treatment of malignant ascites in patients with chemotherapy-refractory ovarian cancer: a phase II study. Int J Gynecol Cancer. 2014 Nov; 24(9):1583-9. PMID: 25254563.
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    26. Donovan KA, Donovan HS, Cella D, Gaines ME, Penson RT, Plaxe SC, von Gruenigen VE, Bruner DW, Reeve BB, Wenzel L. Recommended patient-reported core set of symptoms and quality-of-life domains to measure in ovarian cancer treatment trials. J Natl Cancer Inst. 2014 Jul; 106(7). PMID: 25006190.
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    27. Ward KK, Roncancio AM, Shah NR, Davis MA, Saenz CC, McHale MT, Plaxe SC. Bariatric surgery decreases the risk of uterine malignancy. Gynecol Oncol. 2014 Apr; 133(1):63-6. PMID: 24680593.
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    28. Ward KK, Roncancio AM, Cano MA, Plaxe SC. An ecological analysis of the incidence of invasive squamous cell carcinoma of the cervix in Hispanic women in the United States. Ethn Dis. 2014; 24(2):243-7. PMID: 24804374.
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    29. Ulanday KT, Ward KK, Macera CA, Ji M, Plaxe SC. Regional variation in surgical assessment of lymph nodes for staging among women with early-stage epithelial ovarian cancer. Gynecol Oncol. 2014 Feb; 132(2):411-5. PMID: 24246773.
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    30. Ward KK, Roncancio AM, Shah NR, Davis MA, Saenz CC, McHale MT, Plaxe SC. The risk of uterine malignancy is linearly associated with body mass index in a cohort of US women. Am J Obstet Gynecol. 2013 Dec; 209(6):579.e1-5. PMID: 23938608.
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    31. Kim JS, Ward KK, Shah NR, Saenz CC, McHale MT, Plaxe SC. Excess risk of Clostridium difficile infection in ovarian cancer is related to exposure to broad-spectrum antibiotics. Support Care Cancer. 2013 Nov; 21(11):3103-7. PMID: 23839499.
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    32. Abbott Y, Shah NR, Ward KK, McHale MT, Alvarez EA, Saenz CC, Plaxe SC. Use of psychosocial services increases after a social worker-mediated intervention in gynecology oncology patients. Health Soc Work. 2013 May; 38(2):113-21. PMID: 23865288.
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    33. Ward KK, Tancioni I, Lawson C, Miller NL, Jean C, Chen XL, Uryu S, Kim J, Tarin D, Stupack DG, Plaxe SC, Schlaepfer DD. Inhibition of focal adhesion kinase (FAK) activity prevents anchorage-independent ovarian carcinoma cell growth and tumor progression. Clin Exp Metastasis. 2013 Jun; 30(5):579-94. PMID: 23275034.
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    34. Ward KK, Roncancio AM, Plaxe SC. Women with gynecologic malignancies have a greater incidence of suicide than women with other cancer types. Suicide Life Threat Behav. 2013 Feb; 43(1):109-15. PMID: 23278597.
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    35. Ward KK, Shah NR, Saenz CC, McHale MT, Alvarez EA, Plaxe SC. Changing demographics of cervical cancer in the United States (1973-2008). Gynecol Oncol. 2012 Sep; 126(3):330-3. PMID: 22668881.
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    36. Ward KK, Shah NR, Saenz CC, McHale MT, Alvarez EA, Plaxe SC. Cardiovascular disease is the leading cause of death among endometrial cancer patients. Gynecol Oncol. 2012 Aug; 126(2):176-9. PMID: 22507532.
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    37. McMeekin S, Patel R, Verschraegen C, Celano P, Burke J, Plaxe S, Ghatage P, Giurescu M, Stredder C, Wang Y, Schmelter T. Phase I/II study of sagopilone (ZK-EPO) plus carboplatin in women with recurrent platinum-sensitive ovarian cancer. Br J Cancer. 2012 Jan 03; 106(1):70-6. PMID: 22108514.
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    38. Baughn MR, Plaxe SC, Weidner N. Primary squamous carcinoma of the ovary likely arising from a monodermal cystic mucinous teratoma. Ann Diagn Pathol. 2011 Dec; 15(6):446-9. PMID: 20952274.
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    39. Tipps AM, Plaxe SC, Weidner N. Endometrioid carcinoma with a low-grade spindle cell component: a tumor resembling an adnexal tumor of probable Wolffian origin. Ann Diagn Pathol. 2011 Oct; 15(5):376-81. PMID: 20952275.
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    40. Plaxe SC, Brooks SE, Tian C, Bloss JD, Moore DH, Long HJ. Influence of race on tolerance of platinum-based chemotherapy and clinical outcomes in women with advanced and recurrent cervical cancer: a pooled analysis of 3 Gynecologic Oncology Group studies. Am J Obstet Gynecol. 2008 Nov; 199(5):539.e1-6. PMID: 18565487.
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    41. Plaxe SC. Epidemiology of low-grade serous ovarian cancer. Am J Obstet Gynecol. 2008 Apr; 198(4):459.e1-8; discussion 459.e8-9. PMID: 18395040.
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    42. Plaxe SC, Blessing JA, Olt G, Husseinzadah N, Lentz SS, DeGeest K, Valea FA. A phase II trial of pyrazoloacridine (PZA) in squamous cell carcinoma of the cervix: a Gynecologic Oncology Group study. Cancer Chemother Pharmacol. 2002 Aug; 50(2):151-4. PMID: 12172981.
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    43. Plaxe SC, Blessing JA, Husseinzadeh N, Webster KD, Rader JS, Dunton CJ. Phase II trial of pyrazoloacridine in patients with persistent or recurrent endometrial carcinoma: a Gynecologic Oncology Group Study. Gynecol Oncol. 2002 Feb; 84(2):241-4. PMID: 11812081.
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    44. Plaxe SC, Blessing JA, Morgan MA, Carlson J. Phase II trial of pyrazoloacridine in recurrent platinum-resistant ovarian cancer: a Gynecologic Oncology Group study. Am J Clin Oncol. 2002 Feb; 25(1):45-7. PMID: 11823695.
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    45. Plaxe SC, Blessing JA, Bookman MA, Creasman WT. Phase II trial of pyrazoloacridine in recurrent platinum-sensitive ovarian cancer: a Gynecologic Oncology Group study. Gynecol Oncol. 2002 Jan; 84(1):32-5. PMID: 11748972.
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    46. Plaxe SC, Blessing JA, Lucci JA, Hurteau JA. A phase II trial of pyrazoloacridine (PZA) in squamous carcinoma of the cervix--a Gynecologic Oncology Group Study. Invest New Drugs. 2001; 19(1):77-80. PMID: 11291835.
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    47. de las Alas MM, Christen RD, Gately DP, Weiner DE, Benbatoul K, Kirmani S, D'Agostino HR, Plaxe SC, Darrah D, McClay EF, Aebi S, Howell SB, Los G. Increase in tumor GADD153 mRNA level following treatment correlates with response to paclitaxel. Cancer Chemother Pharmacol. 2000; 45(5):381-8. PMID: 10803921.
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    48. Plaxe SC, Saltzstein SL. Estimation of the duration of the preclinical phase of cervical adenocarcinoma suggests that there is ample opportunity for screening. Gynecol Oncol. 1999 Oct; 75(1):55-61. PMID: 10502426.
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    49. Gooding JM, D'Agostino HB, Plaxe SC. Transcervical metallic stents for drainage of uterine collections. J Vasc Interv Radiol. 1999 May; 10(5):629-33. PMID: 10357490.
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    50. Aebi S, Schnider TW, Los G, Heath DD, Darrah D, Kirmani S, McClay EF, D'Agostino H, Plaxe SC, Fink D, De las Alas MM, Howell SB, Christen RD. A phase II/pharmacokinetic trial of high-dose progesterone in combination with paclitaxel. Cancer Chemother Pharmacol. 1999; 44(3):259-65. PMID: 10453729.
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    51. Buller RE, Skilling JS, Sood AK, Plaxe S, Baergen RN, Lager DJ. Field cancerization: why late "recurrent" ovarian cancer is not recurrent. Am J Obstet Gynecol. 1998 Apr; 178(4):641-9. PMID: 9579425.
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    52. Plaxe SC, Christen RD, O'Quigley J, Braly PS, Freddo JL, McClay E, Heath D, Howell SB. Phase I and pharmacokinetic study of intraperitoneal topotecan. Invest New Drugs. 1998; 16(2):147-53. PMID: 9848578.
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    53. Fink D, Plaxe SC, Brown JF, Baergen RN. Endometrioid ovarian carcinoma in a premenarchal girl: report of a case. Gynecol Oncol. 1997 Nov; 67(2):222-5. PMID: 9367712.
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    54. Plaxe SC, Saltzstein SL. Impact of ethnicity on the incidence of high-risk endometrial carcinoma. Gynecol Oncol. 1997 Apr; 65(1):8-12. PMID: 9103384.
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    55. McClay EF, Braly PD, Kirmani S, Plaxe SC, Kim S, McClay ME, Wilgus L, Howell SB. A phase II trial of intraperitoneal high-dose carboplatin and etoposide with granulocyte macrophage-colony stimulating factor support in patients with ovarian carcinoma. Am J Clin Oncol. 1995 Feb; 18(1):23-6. PMID: 7847254.
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    56. Plaxe S, Freddo J, Kim S, Kirmani S, McClay E, Christen R, Braly P, Howell S. Phase I trial of cisplatin in combination with glutathione. Gynecol Oncol. 1994 Oct; 55(1):82-6. PMID: 7959273.
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    57. Kirmani S, Braly PS, McClay EF, Saltzstein SL, Plaxe SC, Kim S, Cates C, Howell SB. A comparison of intravenous versus intraperitoneal chemotherapy for the initial treatment of ovarian cancer. Gynecol Oncol. 1994 Sep; 54(3):338-44. PMID: 8088611.
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    58. McClay EF, Braly PD, Kirmani S, Plaxe SC, McClay ME, Wilgus L, Kim S, Howell SB. A phase I trial of intraperitoneal carboplatin and etoposide with granulocyte macrophage colony stimulating factor support in patients with intraabdominal malignancies. Cancer. 1994 Jul 15; 74(2):664-9. PMID: 8033046.
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    59. Plaxe SC. Ovarian cancer. Med Sect Proc. 1994; 121-8. PMID: 7659707.
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    60. Christen RD, McClay EF, Plaxe SC, Yen SS, Kim S, Kirmani S, Wilgus LL, Heath DD, Shalinsky DR, Freddo JL. Phase I/pharmacokinetic study of high-dose progesterone and doxorubicin. J Clin Oncol. 1993 Dec; 11(12):2417-26. PMID: 8246031.
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    61. McClay EF, Goel R, Andrews P, Gorelick S, Kirmani S, Kim S, Braly P, Plaxe S, Hoff S, Alcaraz J. A phase I and pharmacokinetic study of intraperitoneal carboplatin and etoposide. Br J Cancer. 1993 Oct; 68(4):783-8. PMID: 8398708.
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    62. Plaxe SC, Braly PS, Freddo JL, McClay E, Christen RD, Kirmani S, Kim S, Heath D, Howell SB. Phase I and pharmacokinetic study of intraperitoneal ormaplatin. Gynecol Oncol. 1993 Oct; 51(1):72-7. PMID: 8244179.
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    63. Bonetti A, Howell SB, McClay E, Kirmani S, Goel R, Plaxe S, Braly P, Kim S. High-dose biweekly intraperitoneal cisplatin: an effective way to increase cisplatin dose intensity. Gynecol Oncol. 1993 Jun; 49(3):318-24. PMID: 8314533.
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    64. Plaxe SC, Braly PS, Freddo JL, McClay E, Kirmani S, Howell SB. Profiles of women age 30-39 and age less than 30 with epithelial ovarian cancer. Obstet Gynecol. 1993 May; 81(5 ( Pt 1)):651-4. PMID: 8469449.
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    65. Kim S, Howell SB, McClay E, Kirmani S, Goel R, Plaxe S, Braly P, Bonetti A. Dose intensification of cisplatin chemotherapy through biweekly administration. Ann Oncol. 1993 Mar; 4(3):221-7. PMID: 8471554.
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    66. Plaxe SC, Braly PS, Dottino PR. A simplified approach to superficial inguinal dissection with sparing of the saphenous vein in patients with carcinoma of the vulva. Surg Gynecol Obstet. 1993 Mar; 176(3):295-6. PMID: 8438204.
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    67. Goel R, McClay EF, Kirmani S, Kim S, Braly PF, Plaxe SC, Alcaraz J, Andrews PA, Reichman B, Markman M. Pharmacokinetic study of intraperitoneal streptozotocin. Clin Invest Med. 1992 Oct; 15(5):420-6. PMID: 1458714.
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    68. Dottino PR, Plaxe SC, Cohen CJ. A phase II trial of adjuvant cisplatin and doxorubicin in stage I epithelial ovarian cancer. Gynecol Oncol. 1991 Dec; 43(3):203-5. PMID: 1752488.
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    69. Isonishi S, Kirmani S, Kim S, Plaxe SC, Braly PS, McClay EF, Howell SB. Phase I and pharmacokinetic trial of intraperitoneal etoposide in combination with the multidrug-resistance-modulating agent dipyridamole. J Natl Cancer Inst. 1991 May 01; 83(9):621-6. PMID: 2023280.
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    70. Howell SB, Kirmani S, McClay EF, Kim S, Braly P, Plaxe S. Intraperitoneal cisplatin-based chemotherapy for ovarian carcinoma. Semin Oncol. 1991 Feb; 18(1 Suppl 3):5-10. PMID: 2003227.
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    71. Dottino PR, Plaxe SC, Beddoe AM, Johnston C, Cohen CJ. Induction chemotherapy followed by radical surgery in cervical cancer. Gynecol Oncol. 1991 Jan; 40(1):7-11. PMID: 1703509.
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    72. Plaxe SC, Deligdisch L, Dottino PR, Cohen CJ. Ovarian intraepithelial neoplasia demonstrated in patients with stage I ovarian carcinoma. Gynecol Oncol. 1990 Sep; 38(3):367-72. PMID: 2227550.
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    73. Plaxe SC, Dottino PR, Cohen CJ. Therapeutic and metabolic effects of high (greater than 1 g/m2) systemic cumulative doses of cis-platinum in patients with ovarian carcinoma. Gynecol Oncol. 1990 May; 37(2):250-3. PMID: 2344969.
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    74. Plaxe SC, Dottino PR, Goodman HM, Deligdisch L, Idelson M, Cohen CJ. Clinical features of advanced ovarian mixed mesodermal tumors and treatment with doxorubicin- and cis-platinum-based chemotherapy. Gynecol Oncol. 1990 May; 37(2):244-9. PMID: 2160905.
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    75. Brodman M, Friedman F, Dottino P, Janus C, Plaxe S, Cohen C. A comparative study of computerized tomography, magnetic resonance imaging, and clinical staging for the detection of early cervix cancer. Gynecol Oncol. 1990 Mar; 36(3):409-12. PMID: 2318454.
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    76. Plaxe SC, Dottino PR, Lipsztein R, Dalton J, Cohen CJ. Clinical features and treatment outcome of patients with epithelial carcinoma of the ovary metastatic to the central nervous system. Obstet Gynecol. 1990 Feb; 75(2):278-81. PMID: 2300357.
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    77. Deligdisch L, Plaxe S, Cohen CJ. Extrauterine pelvic malignant mixed mesodermal tumors. A study of 10 cases with immunohistochemistry. Int J Gynecol Pathol. 1988; 7(4):361-72. PMID: 2466009.
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    78. Lavin PT, Bruckner HW, Plaxe SC. Studies in prognostic factors relating to chemotherapy for advanced gastric cancer. Cancer. 1982 Nov 15; 50(10):2016-23. PMID: 6751515.
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