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Aleem Siddiqui

Title(s)Recall Hcomp, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
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    Epitranscriptomic regulation of HBV gene expression
    NIH R01AI139234Mar 1, 2019 - Feb 29, 2024
    Role: Principal Investigator
    Epitranscriptomic regulation of HBV gene expression
    NIH R56AI139234Jul 16, 2018 - Feb 28, 2019
    Role: Principal Investigator
    Mechanisms of HBV-Induced Innate Immunity
    NIH R01AI125350Jun 23, 2017 - May 31, 2022
    Role: Principal Investigator
    2016 Internatinal Meeting o the Molecular Biology of Hepatitis B Viruses
    NIH R13AI124562Jul 19, 2016 - Jun 30, 2017
    Role: Principal Investigator
    Intervention of HBV DNA synthesis and transcription
    NIH R21AI105939Sep 6, 2013 - Aug 31, 2015
    Role: Principal Investigator
    Hepatitis C Virus-Induced Liver Pathogenesis
    NIH R01DK083479Sep 30, 2010 - Aug 31, 2014
    Role: Principal Investigator
    Role of Lipids in Hepatitis C Virus Maturation
    NIH R01AI085087Jul 1, 2010 - Mar 31, 2020
    Role: Principal Investigator
    Role of Lipids in Hepatitis C Virus Maturation
    NIH R56AI085087Dec 1, 2009 - Mar 31, 2015
    Role: Principal Investigator
    Viral Hepatitis C and Lipid Homeostasis
    NIH R01DK077704Apr 1, 2007 - Dec 31, 2017
    Role: Principal Investigator
    Determinants of Liver Injury in Chronic Hepatitis C Virus Infection
    NIH U19AI066313Sep 1, 2005 - Nov 28, 2010
    Role: Co-Investigator
    Hepatitis C Virus NS5a Protein and Oxidative Stress
    NIH R01DK061566Jan 8, 2003 - Dec 31, 2008
    Role: Principal Investigator
    LIVER-SPECIFIC EXPRESSION OF HBV GENES
    NIH R01CA078769Jan 19, 2000 - Dec 31, 2004
    Role: Principal Investigator
    Comprehensive Biology: Exploiting the Yeast Genome
    NIH P41RR011823Sep 30, 1996 - Jun 30, 2016
    Role: Co-Investigator
    HBV induced Liver Pathogenesis
    NIH R01CA064415Apr 1, 1996 - Sep 30, 2007
    Role: Principal Investigator
    INDO-US VACCINE ACTION PROGRAM
    NIH R03AI031994Sep 15, 1991 - Aug 31, 1994
    Role: Principal Investigator
    HEPATITIS B VIRUS DNA AS COCARCINOGEN IN KAPOSI SARCOMA
    NIH U01AI021182Apr 1, 1984 - Mar 31, 1987
    Role: Principal Investigator
    EXPRESSION OF HBV GENES AND HEPATOMA
    NIH R01CA033135Jul 1, 1982 - Nov 30, 1995
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Regulation of viral hepatitis by N6-methyladenosine RNA methylation. Emerg Microbes Infect. 2025 Dec; 14(1):2544726. Moon JS, Siddiqui A, Kim GW. PMID: 40793828; PMCID: PMC12360054.
      View in: PubMed   Mentions:
    2. SARS-CoV-2 aberrantly elevates mitochondrial bioenergetics to induce robust virus propagation. Signal Transduct Target Ther. 2024 05 11; 9(1):125. Shin HJ, Lee W, Ku KB, Yoon GY, Moon HW, Kim C, Kim MH, Yi YS, Jun S, Kim BT, Oh JW, Siddiqui A, Kim SJ. PMID: 38734691; PMCID: PMC11088672.
      View in: PubMed   Mentions:
    3. The N6-methyladenosine demethylase ALKBH5 regulates the hypoxic HBV transcriptome. PLoS Pathog. 2024 Jan; 20(1):e1011917. Tsukuda S, Harris JM, Magri A, Balfe P, Siddiqui A, Wing PAC, McKeating JA. PMID: 38227578; PMCID: PMC10817175.
      View in: PubMed   Mentions:
    4. Analysis of N6-Methyladenosine Modification of HBV RNA by Methylated RNA Immunoprecipitation. Methods Mol Biol. 2024; 2837:59-66. Kim GW, Siddiqui A. PMID: 39044075.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    5. The N6-methyladenosine demethylase ALKBH5 regulates the hypoxic HBV transcriptome. bioRxiv. 2023 Nov 01. Tsukuda S, Harris JM, Magri A, Balfe P, Wing PA, Siddiqui A, McKeating JA. PMID: 37961409; PMCID: PMC10634982.
      View in: PubMed   Mentions:
    6. Biographical Feature: William Sidney Robinson. J Virol. 2023 08 31; 97(8):e0088023. Gerlich W, Siddiqui A. PMID: 37578229; PMCID: PMC10506470.
      View in: PubMed   Mentions:
    7. N6-Methyladenine Modification of Hepatitis Delta Virus Regulates Its Virion Assembly by Recruiting YTHDF1. J Virol. 2022 10 12; 96(19):e0112422. Kim GW, Moon JS, Gudima SO, Siddiqui A. PMID: 36102650; PMCID: PMC9555152.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    8. N6-methyladenosine modification of the 5' epsilon structure of the HBV pregenome RNA regulates its encapsidation by the viral core protein. Proc Natl Acad Sci U S A. 2022 02 15; 119(7). Kim GW, Moon JS, Siddiqui A. PMID: 35135882; PMCID: PMC8851549.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    9. Hepatitis B Virus X Protein Expression Is Tightly Regulated by N6-Methyladenosine Modification of Its mRNA. J Virol. 2022 02 23; 96(4):e0165521. Kim GW, Siddiqui A. PMID: 34851655; PMCID: PMC8865537.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    10. Monitoring Mitochondrial Function in Aedes albopictus C6/36 Cell Line during Dengue Virus Infection. Insects. 2021 Oct 14; 12(10). Santana-Román ME, Maycotte P, Uribe-Carvajal S, Uribe-Alvarez C, Alvarado-Medina N, Khan M, Siddiqui A, Pando-Robles V. PMID: 34680703; PMCID: PMC8539328.
      View in: PubMed   Mentions:
    11. The RNA Binding Proteins YTHDC1 and FMRP Regulate the Nuclear Export of N6-Methyladenosine-Modified Hepatitis B Virus Transcripts and Affect the Viral Life Cycle. J Virol. 2021 06 10; 95(13):e0009721. Kim GW, Imam H, Siddiqui A. PMID: 33883220; PMCID: PMC8316146.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    12. The role of N6-methyladenosine modification in the life cycle and disease pathogenesis of hepatitis B and C viruses. Exp Mol Med. 2021 03; 53(3):339-345. Kim GW, Siddiqui A. PMID: 33742132; PMCID: PMC8080661.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    13. N6-methyladenosine modification of HCV RNA genome regulates cap-independent IRES-mediated translation via YTHDC2 recognition. Proc Natl Acad Sci U S A. 2021 03 09; 118(10). Kim GW, Siddiqui A. PMID: 33649237; PMCID: PMC7958429.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    14. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1. Autophagy. 2021 Jan; 17(1):1-382. Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM, Ahumada-Castro U, Aits S, Aizawa S, Akkoc Y, Akoumianaki T, Akpinar HA, Al-Abd AM, Al-Akra L, Al-Gharaibeh A, Alaoui-Jamali MA, Alberti S, Alcocer-Gómez E, Alessandri C, Ali M, Alim Al-Bari MA, Aliwaini S, Alizadeh J, Almacellas E, Almasan A, Alonso A, Alonso GD, Altan-Bonnet N, Altieri DC, Álvarez ÉMC, Alves S, Alves da Costa C, Alzaharna MM, Amadio M, Amantini C, Amaral C, Ambrosio S, Amer AO, Ammanathan V, An Z, Andersen SU, Andrabi SA, Andrade-Silva M, Andres AM, Angelini S, Ann D, Anozie UC, Ansari MY, Antas P, Antebi A, Antón Z, Anwar T, Apetoh L, Apostolova N, Araki T, Araki Y, Arasaki K, Araújo WL, Araya J, Arden C, Arévalo MA, Arguelles S, Arias E, Arikkath J, Arimoto H, Ariosa AR, Armstrong-James D, Arnauné-Pelloquin L, Aroca A, Arroyo DS, Arsov I, Artero R, Asaro DML, Aschner M, Ashrafizadeh M, Ashur-Fabian O, Atanasov AG, Au AK, Auberger P, Auner HW, Aurelian L, Autelli R, Avagliano L, Ávalos Y, Aveic S, Aveleira CA, Avin-Wittenberg T, Aydin Y, Ayton S, Ayyadevara S, Azzopardi M, Baba M, Backer JM, Backues SK, Bae DH, Bae ON, Bae SH, Baehrecke EH, Baek A, Baek SH, Baek SH, Bagetta G, Bagniewska-Zadworna A, Bai H, Bai J, Bai X, Bai Y, Bairagi N, Baksi S, Balbi T, Baldari CT, Balduini W, Ballabio A, Ballester M, Balazadeh S, Balzan R, Bandopadhyay R, Banerjee S, Banerjee S, Bánréti Á, Bao Y, Baptista MS, Baracca A, Barbati C, Bargiela A, Barilà D, Barlow PG, Barmada SJ, Barreiro E, Barreto GE, Bartek J, Bartel B, Bartolome A, Barve GR, Basagoudanavar SH, Bassham DC, Bast RC, Basu A, Batoko H, Batten I, Baulieu EE, Baumgarner BL, Bayry J, Beale R, Beau I, Beaumatin F, Bechara LRG, Beck GR, Beers MF, Begun J, Behrends C, Behrens GMN, Bei R, Bejarano E, Bel S, Behl C, Belaid A, Belgareh-Touzé N, Bellarosa C, Belleudi F, Belló Pérez M, Bello-Morales R, Beltran JSO, Beltran S, Benbrook DM, Bendorius M, Benitez BA, Benito-Cuesta I, Bensalem J, Berchtold MW, Berezowska S, Bergamaschi D, Bergami M, Bergmann A, Berliocchi L, Berlioz-Torrent C, Bernard A, Berthoux L, Besirli CG, Besteiro S, Betin VM, Beyaert R, Bezbradica JS, Bhaskar K, Bhatia-Kissova I, Bhattacharya R, Bhattacharya S, Bhattacharyya S, Bhuiyan MS, Bhutia SK, Bi L, Bi X, Biden TJ, Bijian K, Billes VA, Binart N, Bincoletto C, Birgisdottir AB, Bjorkoy G, Blanco G, Blas-Garcia A, Blasiak J, Blomgran R, Blomgren K, Blum JS, Boada-Romero E, Boban M, Boesze-Battaglia K, Boeuf P, Boland B, Bomont P, Bonaldo P, Bonam SR, Bonfili L, Bonifacino JS, Boone BA, Bootman MD, Bordi M, Borner C, Bornhauser BC, Borthakur G, Bosch J, Bose S, Botana LM, Botas J, Boulanger CM, Boulton ME, Bourdenx M, Bourgeois B, Bourke NM, Bousquet G, Boya P, Bozhkov PV, Bozi LHM, Bozkurt TO, Brackney DE, Brandts CH, Braun RJ, Braus GH, Bravo-Sagua R, Bravo-San Pedro JM, Brest P, Bringer MA, Briones-Herrera A, Broaddus VC, Brodersen P, Brodsky JL, Brody SL, Bronson PG, Bronstein JM, Brown CN, Brown RE, Brum PC, Brumell JH, Brunetti-Pierri N, Bruno D, Bryson-Richardson RJ, Bucci C, Buchrieser C, Bueno M, Buitrago-Molina LE, Buraschi S, Buch S, Buchan JR, Buckingham EM, Budak H, Budini M, Bultynck G, Burada F, Burgoyne JR, Burón MI, Bustos V, Büttner S, Butturini E, Byrd A, Cabas I, Cabrera-Benitez S, Cadwell K, Cai J, Cai L, Cai Q, Cairó M, Calbet JA, Caldwell GA, Caldwell KA, Call JA, Calvani R, Calvo AC, Calvo-Rubio Barrera M, Camara NO, Camonis JH, Camougrand N, Campanella M, Campbell EM, Campbell-Valois FX, Campello S, Campesi I, Campos JC, et al. PMID: 33634751; PMCID: PMC7996087.
      View in: PubMed   Mentions: 1317     Fields:    Translation:HumansAnimalsCells
    15. Hepatitis B virus X protein recruits methyltransferases to affect cotranscriptional N6-methyladenosine modification of viral/host RNAs. Proc Natl Acad Sci U S A. 2021 01 19; 118(3). Kim GW, Siddiqui A. PMID: 33397803; PMCID: PMC7826408.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    16. Epitranscriptomic(N6-methyladenosine) Modification of Viral RNA and Virus-Host Interactions. Front Cell Infect Microbiol. 2020; 10:584283. Imam H, Kim GW, Siddiqui A. PMID: 33330128; PMCID: PMC7732492.
      View in: PubMed   Mentions: 39     Fields:    Translation:Cells
    17. HBV-Induced Increased N6 Methyladenosine Modification of PTEN RNA Affects Innate Immunity and Contributes to HCC. Hepatology. 2021 02; 73(2):533-547. Kim GW, Imam H, Khan M, Mir SA, Kim SJ, Yoon SK, Hur W, Siddiqui A. PMID: 32394474; PMCID: PMC7655655.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansCells
    18. Retraction for Waris et al., "Hepatitis C Virus Induces Proteolytic Cleavage of Sterol Regulatory Element Binding Proteins and Stimulates Their Phosphorylation via Oxidative Stress". J Virol. 2020 09 15; 94(19). Waris G, Felmlee DJ, Negro F, Siddiqui A. PMID: 32934072; PMCID: PMC7495369.
      View in: PubMed   Mentions: 1     Fields:    
    19. Retraction for Nasimuzzaman et al., "Hepatitis C Virus Stabilizes Hypoxia-Inducible Factor 1α and Stimulates the Synthesis of Vascular Endothelial Growth Factor". J Virol. 2020 09 15; 94(19). Nasimuzzaman M, Waris G, Mikolon D, Stupack DG, Siddiqui A. PMID: 32934071; PMCID: PMC7495360.
      View in: PubMed   Mentions:    Fields:    
    20. Retraction for Waris and Siddiqui, "Hepatitis C Virus Stimulates the Expression of Cyclooxygenase-2 via Oxidative Stress: Role of Prostaglandin E2 in RNA Replication". J Virol. 2020 09 15; 94(19). Waris G, Siddiqui A. PMID: 32934070; PMCID: PMC7495363.
      View in: PubMed   Mentions:
    21. Retraction for Waris et al., "Hepatitis C Virus (HCV) Constitutively Activates STAT-3 via Oxidative Stress: Role of STAT-3 in HCV Replication". J Virol. 2020 09 15; 94(19). Waris G, Turkson J, Hassanein T, Siddiqui A. PMID: 32934069; PMCID: PMC7495377.
      View in: PubMed   Mentions:
    22. N6-Methyladenosine modification of hepatitis B and C viral RNAs attenuates host innate immunity via RIG-I signaling. J Biol Chem. 2020 09 11; 295(37):13123-13133. Kim GW, Imam H, Khan M, Siddiqui A. PMID: 32719095; PMCID: PMC7489896.
      View in: PubMed   Mentions: 88     Fields:    Translation:HumansCells
    23. Editorial: Viral Evasion Mechanisms of the Host Response. Front Cell Infect Microbiol. 2020; 10:90. Gómez RM, Carrera Silva EA, Abrahão JS, Lim SP, Siddiqui A. PMID: 32181162; PMCID: PMC7059185.
      View in: PubMed   Mentions:
    24. Interferon-stimulated gene 20 (ISG20) selectively degrades N6-methyladenosine modified Hepatitis B Virus transcripts. PLoS Pathog. 2020 02; 16(2):e1008338. Imam H, Kim GW, Mir SA, Khan M, Siddiqui A. PMID: 32059034; PMCID: PMC7046284.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansCells
    25. Revisiting Hepatitis B Virus: Challenges of Curative Therapies. J Virol. 2019 10 15; 93(20). Hu J, Protzer U, Siddiqui A. PMID: 31375584; PMCID: PMC6798116.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansCells
    26. Withdrawal: Hepatitis C virus NS5A and subgenomic replicon activate NF- κ B via tyrosine phosphorylation of I κ B α and its degradation by calpain protease. J Biol Chem. 2018 12 28; 293(52):20012. Waris G, Livolsi A, Imbert V, Peyron JF, Siddiqui A. PMID: 30593533; PMCID: PMC6311525.
      View in: PubMed   Mentions:    Fields:    
    27. Subversion of cellular autophagy during virus infection: Insights from hepatitis B and hepatitis C viruses. Liver Res. 2018 Sep; 2(3):146-156. Khan M, Imam H, Siddiqui A. PMID: 31803515; PMCID: PMC6892584.
      View in: PubMed   Mentions: 14  
    28. N6-methyladenosine modification of hepatitis B virus RNA differentially regulates the viral life cycle. Proc Natl Acad Sci U S A. 2018 08 28; 115(35):8829-8834. Imam H, Khan M, Gokhale NS, McIntyre ABR, Kim GW, Jang JY, Kim SJ, Mason CE, Horner SM, Siddiqui A. PMID: 30104368; PMCID: PMC6126736.
      View in: PubMed   Mentions: 140     Fields:    Translation:HumansCells
    29. The essential role of mitochondrial dynamics in antiviral immunity. Mitochondrion. 2018 07; 41:21-27. Kim SJ, Ahn DG, Syed GH, Siddiqui A. PMID: 29246869; PMCID: PMC5988924.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    30. Ginsenoside Rg3 restores hepatitis C virus-induced aberrant mitochondrial dynamics and inhibits virus propagation. Hepatology. 2017 09; 66(3):758-771. Kim SJ, Jang JY, Kim EJ, Cho EK, Ahn DG, Kim C, Park HS, Jeong SW, Lee SH, Kim SG, Kim YS, Kim HS, Kim BS, Lee J, Siddiqui A. PMID: 28329914; PMCID: PMC5755973.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    31. Hepatitis C Virus Lipoviroparticles Assemble in the Endoplasmic Reticulum (ER) and Bud off from the ER to the Golgi Compartment in COPII Vesicles. J Virol. 2017 08 01; 91(15). Syed GH, Khan M, Yang S, Siddiqui A. PMID: 28515296; PMCID: PMC5512234.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    32. Hepatitis B Virus-Induced Parkin-Dependent Recruitment of Linear Ubiquitin Assembly Complex (LUBAC) to Mitochondria and Attenuation of Innate Immunity. PLoS Pathog. 2016 06; 12(6):e1005693. Khan M, Syed GH, Kim SJ, Siddiqui A. PMID: 27348524; PMCID: PMC4922663.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansCells
    33. Technical standards for hepatitis B virus X protein (HBx) research. Hepatology. 2015 Apr; 61(4):1416-24. Slagle BL, Andrisani OM, Bouchard MJ, Lee CG, Ou JH, Siddiqui A. PMID: 25099228; PMCID: PMC4320676.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    34. Hepatitis C virus attenuates mitochondrial lipid β-oxidation by downregulating mitochondrial trifunctional-protein expression. J Virol. 2015 Apr; 89(8):4092-101. Amako Y, Munakata T, Kohara M, Siddiqui A, Peers C, Harris M. PMID: 25673715; PMCID: PMC4442397.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    35. Mitochondrial dynamics and viral infections: A close nexus. Biochim Biophys Acta. 2015 Oct; 1853(10 Pt B):2822-33. Khan M, Syed GH, Kim SJ, Siddiqui A. PMID: 25595529; PMCID: PMC4500740.
      View in: PubMed   Mentions: 111     Fields:    Translation:HumansAnimalsCells
    36. Evolutionary trends and functional anatomy of the human expanded autophagy network. Autophagy. 2015; 11(9):1652-67. Till A, Saito R, Merkurjev D, Liu JJ, Syed GH, Kolnik M, Siddiqui A, Glas M, Scheffler B, Ideker T, Subramani S. PMID: 26103419; PMCID: PMC4590607.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    37. Nordihydroguaiaretic acid (NDGA) inhibits replication and viral morphogenesis of dengue virus. Antiviral Res. 2014 Sep; 109:132-40. Soto-Acosta R, Bautista-Carbajal P, Syed GH, Siddiqui A, Del Angel RM. PMID: 25017471.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    38. Hepatitis C virus triggers mitochondrial fission and attenuates apoptosis to promote viral persistence. Proc Natl Acad Sci U S A. 2014 Apr 29; 111(17):6413-8. Kim SJ, Syed GH, Khan M, Chiu WW, Sohail MA, Gish RG, Siddiqui A. PMID: 24733894; PMCID: PMC4035934.
      View in: PubMed   Mentions: 200     Fields:    Translation:HumansCells
    39. Hepatitis C virus stimulates low-density lipoprotein receptor expression to facilitate viral propagation. J Virol. 2014 Mar; 88(5):2519-29. Syed GH, Tang H, Khan M, Hassanein T, Liu J, Siddiqui A. PMID: 24352472; PMCID: PMC3958050.
      View in: PubMed   Mentions: 51     Fields:    Translation:HumansCells
    40. Hepatitis B virus disrupts mitochondrial dynamics: induces fission and mitophagy to attenuate apoptosis. PLoS Pathog. 2013; 9(12):e1003722. Kim SJ, Khan M, Quan J, Till A, Subramani S, Siddiqui A. PMID: 24339771; PMCID: PMC3855539.
      View in: PubMed   Mentions: 199     Fields:    Translation:HumansCells
    41. Hepatitis C virus induces the mitochondrial translocation of Parkin and subsequent mitophagy. PLoS Pathog. 2013 Mar; 9(3):e1003285. Kim SJ, Syed GH, Siddiqui A. PMID: 23555273; PMCID: PMC3610669.
      View in: PubMed   Mentions: 124     Fields:    Translation:HumansCells
    42. Phosphoinositides in the hepatitis C virus life cycle. Viruses. 2012 Oct 19; 4(10):2340-58. Bishé B, Syed G, Siddiqui A. PMID: 23202467; PMCID: PMC3497055.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    43. Role of phosphatidylinositol 4-phosphate (PI4P) and its binding protein GOLPH3 in hepatitis C virus secretion. J Biol Chem. 2012 Aug 10; 287(33):27637-47. Bishé B, Syed GH, Field SJ, Siddiqui A. PMID: 22745132; PMCID: PMC3431621.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    44. Effects of hypolipidemic agent nordihydroguaiaretic acid on lipid droplets and hepatitis C virus. Hepatology. 2011 Dec; 54(6):1936-46. Syed GH, Siddiqui A. PMID: 21858850; PMCID: PMC3236615.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    45. Protein kinase D negatively regulates hepatitis C virus secretion through phosphorylation of oxysterol-binding protein and ceramide transfer protein. J Biol Chem. 2011 Apr 01; 286(13):11265-74. Amako Y, Syed GH, Siddiqui A. PMID: 21285358; PMCID: PMC3064182.
      View in: PubMed   Mentions: 53     Fields:    Translation:Cells
    46. Hepatitis C virus hijacks host lipid metabolism. Trends Endocrinol Metab. 2010 Jan; 21(1):33-40. Syed GH, Amako Y, Siddiqui A. PMID: 19854061; PMCID: PMC2818172.
      View in: PubMed   Mentions: 185     Fields:    Translation:HumansAnimalsCells
    47. Role of oxysterol binding protein in hepatitis C virus infection. J Virol. 2009 Sep; 83(18):9237-46. Amako Y, Sarkeshik A, Hotta H, Yates J, Siddiqui A. PMID: 19570870; PMCID: PMC2738263.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansCells
    48. Hepatitis C virus stabilizes hypoxia-inducible factor 1alpha and stimulates the synthesis of vascular endothelial growth factor. J Virol. 2007 Oct; 81(19):10249-57. Nasimuzzaman M, Waris G, Mikolon D, Stupack DG, Siddiqui A. PMID: 17626077; PMCID: PMC2045478.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansAnimalsCells
    49. Hepatitis C virus induces proteolytic cleavage of sterol regulatory element binding proteins and stimulates their phosphorylation via oxidative stress. J Virol. 2007 Aug; 81(15):8122-30. Waris G, Felmlee DJ, Negro F, Siddiqui A. PMID: 17507484; PMCID: PMC1951320.
      View in: PubMed   Mentions: 112     Fields:    Translation:HumansAnimalsCells
    50. Hepatitis B virus X protein stimulates the mitochondrial translocation of Raf-1 via oxidative stress. J Virol. 2007 Jun; 81(12):6757-60. Chen J, Siddiqui A. PMID: 17428866; PMCID: PMC1900104.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    51. Hepatitis C virus nonstructural proteins inhibit apolipoprotein B100 secretion. J Biol Chem. 2005 Dec 02; 280(48):39802-8. Domitrovich AM, Felmlee DJ, Siddiqui A. PMID: 16203724.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    52. Hepatitis C virus stimulates the expression of cyclooxygenase-2 via oxidative stress: role of prostaglandin E2 in RNA replication. J Virol. 2005 Aug; 79(15):9725-34. Waris G, Siddiqui A. PMID: 16014934; PMCID: PMC1181604.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    53. Role of La autoantigen and polypyrimidine tract-binding protein in HCV replication. Virology. 2005 Apr 25; 335(1):72-86. Domitrovich AM, Diebel KW, Ali N, Sarker S, Siddiqui A. PMID: 15823607.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    54. Hepatitis C virus, ER stress, and oxidative stress. Trends Microbiol. 2005 Apr; 13(4):159-63. Tardif KD, Waris G, Siddiqui A. PMID: 15817385.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansCells
    55. Hepatitis C virus (HCV) constitutively activates STAT-3 via oxidative stress: role of STAT-3 in HCV replication. J Virol. 2005 Feb; 79(3):1569-80. Waris G, Turkson J, Hassanein T, Siddiqui A. PMID: 15650183; PMCID: PMC544105.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    56. Hepatitis C virus suppresses the IRE1-XBP1 pathway of the unfolded protein response. J Biol Chem. 2004 Apr 23; 279(17):17158-64. Tardif KD, Mori K, Kaufman RJ, Siddiqui A. PMID: 14960590.
      View in: PubMed   Mentions: 137     Fields:    Translation:HumansAnimalsCells
    57. Two-step affinity purification of the hepatitis C virus ribonucleoprotein complex. RNA. 2004 Feb; 10(2):321-9. Waris G, Sarker S, Siddiqui A. PMID: 14730030; PMCID: PMC1370543.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    58. [The effect of Hepatitis C virus nonstructural protein 5A on cell cycling]. Zhonghua Gan Zang Bing Za Zhi. 2004 Jan; 12(1):47-8. Gong GZ, Siddiqui A, Su XS. PMID: 14761287.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    59. Cell surface expression of major histocompatibility complex class I molecules is reduced in hepatitis C virus subgenomic replicon-expressing cells. J Virol. 2003 Nov; 77(21):11644-50. Tardif KD, Siddiqui A. PMID: 14557650; PMCID: PMC229359.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    60. Hepatitis C virus NS5A and subgenomic replicon activate NF-kappaB via tyrosine phosphorylation of IkappaBalpha and its degradation by calpain protease. J Biol Chem. 2003 Oct 17; 278(42):40778-87. Waris G, Livolsi A, Imbert V, Peyron JF, Siddiqui A. PMID: 12909638.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    61. Cell-free replication of the hepatitis C virus subgenomic replicon. J Virol. 2002 Dec; 76(23):12001-7. Ali N, Tardif KD, Siddiqui A. PMID: 12414942; PMCID: PMC136887.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    62. Endoplasmic reticulum (ER) stress: hepatitis C virus induces an ER-nucleus signal transduction pathway and activates NF-kappaB and STAT-3. Biochem Pharmacol. 2002 Nov 15; 64(10):1425-30. Waris G, Tardif KD, Siddiqui A. PMID: 12417255.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    63. Hepatitis C virus subgenomic replicons induce endoplasmic reticulum stress activating an intracellular signaling pathway. J Virol. 2002 Aug; 76(15):7453-9. Tardif KD, Mori K, Siddiqui A. PMID: 12097557; PMCID: PMC136367.
      View in: PubMed   Mentions: 109     Fields:    Translation:HumansCells
    64. Interaction between STAT-3 and HNF-3 leads to the activation of liver-specific hepatitis B virus enhancer 1 function. J Virol. 2002 Mar; 76(6):2721-9. Waris G, Siddiqui A. PMID: 11861839; PMCID: PMC135980.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    65. Characterization of the mitochondrial association of hepatitis B virus X protein, HBx. Mitochondrion. 2002 Feb; 1(4):349-59. Huh KW, Siddiqui A. PMID: 16120289.
      View in: PubMed   Mentions: 19     Fields:    
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