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Sonia Ramamoorthy

TitleProfessor Of Clinical
InstitutionUniversity of California San Diego
DepartmentSurgery
Address9500 Gilman Drive #0987
La Jolla CA 92093
Phone858-822-6277
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    Profile
    Dr. Sonia Ramamoorthy is a surgeon who specializes in surgery of the colon and rectum. She cares for patients who have cancer of the colon, rectum, and anus, as well as benign conditions such as diverticulitis and inflammatory bowel disease. She also specializes in treating pelvic floor disorders and fecal incontinence. She is certified by both the American Board of Surgery and the American Board of Colon and Rectal Surgery.

    Dr. Ramamoorthy performs open and minimally invasive colorectal surgeries as well as all standard general surgery procedures. She has advanced training in colon and rectal surgery and has special certification in minimally invasive surgical techniques to treat cancers as well as other conditions in the colon, rectum, and anus. Dr. Ramamoorthy’s surgeries for benign conditions include laparoscopic colectomy for benign polyps, diverticular disease, inflammatory bowel disease, constipation, and prolapse.

    Dr. Ramamoorthy is active in the surgical community as an instructor who trains other surgeons to perform laparoscopic colorectal surgery.

    Dr. Ramamoorthy’s research interests include colorectal and anal cancer, Crohn’s disease and ulcerative colitis, and pelvic floor disorders. Here at UC San Diego, Dr. Ramamoorthy is part of the Translational Oncology Program at the Moores UC San Diego Cancer Center, where her ongoing research focuses on developing techniques for determining a patient’s risk of cancer recurrence after surgery for early rectal cancer.

    Dr. Ramamoorthy’s current research projects also include a study of the role of microsatellite instability (MIS) in squamous cell cancer of the anus. Squamous cell cancer of the anus is becoming more common in the United States, particularly in individuals who are immunocompromised and those who are HIV/HPV-positive. Her research is supported by a grant from the American Cancer Society.

    Dr. Ramamoorthy speaks English and some Spanish.


    Collapse Research 
    Collapse Research Activities and Funding
    1/2 SDSU/UCSD Cancer Center Comprehensive Partnership
    NIH/NCI U54CA132379Dec 1, 2007 - Aug 31, 2020
    Role: Co-Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Zhao B, Cajas-Monson LC, Ramamoorthy S. Malpractice allegations: A reality check for resident physicians. Am J Surg. 2018 Aug 23. PMID: 30172360.
      View in: PubMed
    2. Hildreth A, Valasek MA, Thung I, Savides T, Sivagnanam M, Ramamoorthy S, Huang SC. Biallelic Mismatch Repair Deficiency in an Adolescent Female. Case Rep Genet. 2018; 2018:8657823. PMID: 30155321.
      View in: PubMed
    3. Weiss A, Parina R, Tapia VJ, Sood D, Lee KC, Horgan S, Freischlag JA, Blair SL, Ramamoorthy SL. Assessing the domino effect: Female physician industry payments fall short, parallel gender inequalities in medicine. Am J Surg. 2018 Jul 24. PMID: 30093089.
      View in: PubMed
    4. Liu S, Suzuki T, Murray BW, Parry L, Johnson CS, Horgan S, Ramamoorthy S, Eisenstein S. Robotic transanal minimally invasive surgery (TAMIS) with the newest robotic surgical platform: a multi-institutional North American experience. Surg Endosc. 2018 Jul 13. PMID: 30006844.
      View in: PubMed
    5. Nguyen V, Marmor RA, Ramamoorthy SL, Costantini TW, Baumgartner JM, Berumen J, Jacobsen GR, Sicklick JK. The Use of Solicited Publishing by Academic Surgeons. Surgery. 2018 Apr 30. PMID: 29724409.
      View in: PubMed
    6. Nguyen V, Marmor RA, Ramamoorthy SL, Blair SL, Clary BM, Sicklick JK. Academic Surgical Oncologists' Productivity Correlates with Gender, Grant Funding, and Institutional NCI Comprehensive Cancer Center Affiliation. Ann Surg Oncol. 2018 Mar 29. PMID: 29600347.
      View in: PubMed
    7. Kamboj M, Childers T, Sugalski J, Antonelli D, Bingener-Casey J, Cannon J, Cluff K, Davis KA, Dellinger EP, Dowdy SC, Duncan K, Fedderson J, Glasgow R, Hall B, Hirsch M, Hutter M, Kimbro L, Kuvshinoff B, Makary M, Morris M, Nehring S, Ramamoorthy S, Scott R, Sovel M, Strong V, Webster A, Wick E, Aguilar JG, Carlson R, Sepkowitz K. Risk of Surgical Site Infection (SSI) following Colorectal Resection Is Higher in Patients With Disseminated Cancer: An NCCN Member Cohort Study. Infect Control Hosp Epidemiol. 2018 Mar 19; 1-8. PMID: 29553001.
      View in: PubMed
    8. Cosman BC, Cajas-Monson LC, Ramamoorthy SL. Twenty Years of a Veterans' Spinal Cord Injury Colorectal Clinic: Flexible Sigmoidoscopy and Multiple Hemorrhoid Ligation. Dis Colon Rectum. 2017 Apr; 60(4):399-404. PMID: 28267007.
      View in: PubMed
    9. Fumery M, Dulai PS, Gupta S, Prokop LJ, Ramamoorthy S, Sandborn WJ, Singh S. Incidence, Risk Factors, and Outcomes of Colorectal Cancer in Patients With Ulcerative Colitis With Low-Grade Dysplasia: A Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol. 2017 May; 15(5):665-674.e5. PMID: 27916678.
      View in: PubMed
    10. Singh S, Dulai PS, Zarrinpar A, Ramamoorthy S, Sandborn WJ. Obesity in IBD: epidemiology, pathogenesis, disease course and treatment outcomes. Nat Rev Gastroenterol Hepatol. 2017 02; 14(2):110-121. PMID: 27899815.
      View in: PubMed
    11. Lopez NE, Weiss AC, Robles J, Fanta P, Ramamoorthy SL. A systematic review of clinically available gene expression profiling assays for stage II colorectal cancer: initial steps toward genetic staging. Am J Surg. 2016 Oct; 212(4):700-714. PMID: 27637150.
      View in: PubMed
    12. Hu WH, Chen HH, Lee KC, Liu L, Eisenstein S, Parry L, Cosman B, Ramamoorthy S. Assessment of the Addition of Hypoalbuminemia to ACS-NSQIP Surgical Risk Calculator in Colorectal Cancer. Medicine (Baltimore). 2016 Mar; 95(10):e2999. PMID: 26962812; PMCID: PMC4998893.
    13. Hu WH, Miyai K, Sporn JC, Luo L, Wang JY, Cosman B, Ramamoorthy S. Loss of histone variant macroH2A2 expression associates with progression of anal neoplasm. J Clin Pathol. 2016 Jul; 69(7):627-31. PMID: 26658220; PMCID: PMC4941135.
    14. Hu WH, Cajas-Monson LC, Eisenstein S, Parry L, Cosman B, Ramamoorthy S. Preoperative malnutrition assessments as predictors of postoperative mortality and morbidity in colorectal cancer: an analysis of ACS-NSQIP. Nutr J. 2015 Sep 07; 14:91. PMID: 26345703; PMCID: PMC4561437.
    15. Hu WH, Miyai K, Cajas-Monson LC, Luo L, Liu L, Ramamoorthy SL. Tumor-infiltrating CD8(+) T lymphocytes associated with clinical outcome in anal squamous cell carcinoma. J Surg Oncol. 2015 Sep; 112(4):421-6. PMID: 26287957.
      View in: PubMed
    16. Hu WH, Cajas-Monson LC, Eisenstein S, Parry L, Ramamoorthy S. Association of dialysis with adverse postoperative outcomes in colorectal cancer-an analysis of ACS-NSQIP. Int J Colorectal Dis. 2015 Nov; 30(11):1557-62. PMID: 26243472.
      View in: PubMed
    17. Gan TJ, Robinson SB, Oderda GM, Scranton R, Pepin J, Ramamoorthy S. Impact of postsurgical opioid use and ileus on economic outcomes in gastrointestinal surgeries. Curr Med Res Opin. 2015 Apr; 31(4):677-86. PMID: 25586296.
      View in: PubMed
    18. Lopez NE, Peterson CY, Ramamoorthy SL, McLemore EC, Sedrak MF, Lowy AM, Horgan S, Talamini MA, Sicklick JK. Single-incision laparoscopic surgery through an ostomy site: a natural approach by an unnatural orifice. Surg Laparosc Endosc Percutan Tech. 2015 Feb; 25(1):74-8. PMID: 24743670.
      View in: PubMed
    19. Fuchs HF, Broderick RC, Harnsberger CR, Chang DC, Mclemore EC, Ramamoorthy S, Horgan S. Variation of outcome and charges in operative management for diverticulitis. Surg Endosc. 2015 Nov; 29(11):3090-6. PMID: 25539698.
      View in: PubMed
    20. Broderick RC, Fuchs HF, Harnsberger CR, Chang DC, McLemore E, Ramamoorthy S, Horgan S. The price of decreased mortality in the operative management of diverticulitis. Surg Endosc. 2015 May; 29(5):1185-91. PMID: 25159639.
      View in: PubMed
    21. Ward NT, Ramamoorthy SL, Chang DC, Parsons JK. Laparoscopic appendectomy is safer than open appendectomy in an elderly population. JSLS. 2014 Jul-Sep; 18(3). PMID: 25392668; PMCID: PMC4208904.
    22. Weiss A, Lee KC, Tapia V, Chang D, Freischlag J, Blair SL, Ramamoorthy S. Equity in surgical leadership for women: more work to do. Am J Surg. 2014 Sep; 208(3):494-8. PMID: 24933664.
      View in: PubMed
    23. McLemore EC, Weston LA, Coker AM, Jacobsen GR, Talamini MA, Horgan S, Ramamoorthy SL. Transanal minimally invasive surgery for benign and malignant rectal neoplasia. Am J Surg. 2014 Sep; 208(3):372-81. PMID: 24832238.
      View in: PubMed
    24. Viscusi ER, Sinatra R, Onel E, Ramamoorthy SL. The safety of liposome bupivacaine, a novel local analgesic formulation. Clin J Pain. 2014 Feb; 30(2):102-10. PMID: 23446090.
      View in: PubMed
    25. Simpson DR, Martínez ME, Gupta S, Hattangadi-Gluth J, Mell LK, Heestand G, Fanta P, Ramamoorthy S, Le QT, Murphy JD. Racial disparity in consultation, treatment, and the impact on survival in metastatic colorectal cancer. J Natl Cancer Inst. 2013 Dec 04; 105(23):1814-20. PMID: 24231453; PMCID: PMC4383284.
    26. Peterson CY, Palazzi K, Parsons JK, Chang DC, Ramamoorthy SL. The prevalence of laparoscopy and patient safety outcomes: an analysis of colorectal resections. Surg Endosc. 2014 Feb; 28(2):608-16. PMID: 24091552.
      View in: PubMed
    27. Metildi C, McLemore EC, Tran T, Chang D, Cosman B, Ramamoorthy SL, Saltzstein SL, Sadler GR. Incidence and survival patterns of rare anal canal neoplasms using the surveillance epidemiology and end results registry. Am Surg. 2013 Oct; 79(10):1068-74. PMID: 24160801; PMCID: PMC4209843.
    28. Bazzi WM, Stroup SP, Cohen SA, Sisul DM, Liss MA, Masterson JH, Kopp RP, Gudeman SR, Leeflang E, Palazzi KL, Ramamoorthy S, Kane CJ, Horgan S, Derweesh IH. Comparison of transrectal and transvaginal hybrid natural orifice transluminal endoscopic surgery partial nephrectomy in the porcine model. Urology. 2013 Jul; 82(1):84-9. PMID: 23676357.
      View in: PubMed
    29. McLemore EC, Coker AM, Devaraj B, Chakedis J, Maawy A, Inui T, Talamini MA, Horgan S, Peterson MR, Sylla P, Ramamoorthy S. TAMIS-assisted laparoscopic low anterior resection with total mesorectal excision in a cadaveric series. Surg Endosc. 2013 Sep; 27(9):3478-84. PMID: 23494511; PMCID: PMC4343257.
    30. Horgan S, Meireles OR, Jacobsen GR, Sandler BJ, Ferreres A, Ramamoorthy S, Savides T, Katagiri T, Dotai T, Sedrak M, Majid SF, Nijhawan S, Talamini MA. Broad clinical utilization of NOTES: is it safe? Surg Endosc. 2013 Jun; 27(6):1872-80. PMID: 23479251.
      View in: PubMed
    31. Ramamoorthy S, Obias V. Unique complications of robotic colorectal surgery. Surg Clin North Am. 2013 Feb; 93(1):273-86. PMID: 23177076.
      View in: PubMed
    32. Parra-Davila E, Ramamoorthy S. Lap colectomy and robotics for colon cancer. Surg Oncol Clin N Am. 2013 Jan; 22(1):143-51, vii. PMID: 23158090.
      View in: PubMed
    33. Dasta J, Ramamoorthy S, Patou G, Sinatra R. Bupivacaine liposome injectable suspension compared with bupivacaine HCl for the reduction of opioid burden in the postsurgical setting. Curr Med Res Opin. 2012 Oct; 28(10):1609-15. PMID: 22900785.
      View in: PubMed
    34. Bazzi WM, Stroup SP, Cohen SA, Dotai T, Kopp RP, Colangelo C, Raheem OA, Ramamoorthy S, Talamini M, Horgan S, Kane CJ, Derweesh IH. Feasibility of transrectal hybrid natural orifice transluminal endoscopic surgery (NOTES) nephrectomy in the cadaveric model. Urology. 2012 Sep; 80(3):590-5. PMID: 22925236.
      View in: PubMed
    35. Pola S, Patel D, Ramamoorthy S, McLemore E, Fahmy M, Rivera-Nieves J, Chang JT, Evans E, Docherty M, Talamini M, Sandborn WJ. Strategies for the care of adults hospitalized for active ulcerative colitis. Clin Gastroenterol Hepatol. 2012 Dec; 10(12):1315-1325.e4. PMID: 22835577; PMCID: PMC4226798.
    36. Peterson CY, McLemore EC, Horgan S, Talamini MA, Ramamoorthy SL. Technical aspects of robotic proctectomy. Surg Laparosc Endosc Percutan Tech. 2012 Jun; 22(3):189-93. PMID: 22678311.
      View in: PubMed
    37. Fahmy M, Ramamoorthy S, Hata T, Sandborn WJ. Ustekinumab for peristomal pyoderma gangrenosum. Am J Gastroenterol. 2012 May; 107(5):794-5. PMID: 22552250.
      View in: PubMed
    38. Bergese SD, Ramamoorthy S, Patou G, Bramlett K, Gorfine SR, Candiotti KA. Efficacy profile of liposome bupivacaine, a novel formulation of bupivacaine for postsurgical analgesia. J Pain Res. 2012; 5:107-16. PMID: 22570563; PMCID: PMC3346068.
    39. McLemore EC, Ramamoorthy S, Peterson CY, Bass BL. Women in surgery: bright, sharp, brave, and temperate. Perm J. 2012; 16(3):54-9. PMID: 23012600; PMCID: PMC3442763.
    40. McLemore EC, Cullen J, Horgan S, Talamini MA, Ramamoorthy S. Robotic-assisted laparoscopic stage II restorative proctectomy for toxic ulcerative colitis. Int J Med Robot. 2012 Jun; 8(2):178-83. PMID: 22113993.
      View in: PubMed
    41. Rajasekaran MR, Jiang Y, Bhargava V, Ramamoorthy S, Lieber RL, Mittal RK. Sustained improvement in the anal sphincter function following surgical plication of rabbit external anal sphincter muscle. Dis Colon Rectum. 2011 Nov; 54(11):1373-80. PMID: 21979181.
      View in: PubMed
    42. Bazzi WM, Wagner O, Stroup SP, Silberstein JL, Belkind N, Katagiri T, Paleari J, Duro A, Ramamoorthy S, Talamini MA, Horgan S, Derweesh IH. Transrectal hybrid natural orifice transluminal endoscopic surgery (NOTES) nephrectomy in a porcine model. Urology. 2011 Mar; 77(3):518-23. PMID: 21376997.
      View in: PubMed
    43. Ramamoorthy S, Devaraj B, Miyai K, Luo L, Liu YT, Boland CR, Goel A, Carethers JM. John Cunningham virus T-antigen expression in anal carcinoma. Cancer. 2011 Jun 01; 117(11):2379-85. PMID: 24048785; PMCID: PMC3060305.
    44. Ramamoorthy S, Liu YT, Luo L, Miyai K, Lu Q, Carethers JM. Detection of multiple human papillomavirus genotypes in anal carcinoma. Infect Agent Cancer. 2010 Oct 12; 5:17. PMID: 20939896; PMCID: PMC2964599.
    45. Dong H, Shim KN, Li JM, Estrema C, Ornelas TA, Nguyen F, Liu S, Ramamoorthy SL, Ho S, Carethers JM, Chow JY. Molecular mechanisms underlying Ca2+-mediated motility of human pancreatic duct cells. Am J Physiol Cell Physiol. 2010 Dec; 299(6):C1493-503. PMID: 20861471; PMCID: PMC3006328.
    46. Devaraj B, Lee A, Cabrera BL, Miyai K, Luo L, Ramamoorthy S, Keku T, Sandler RS, McGuire KL, Carethers JM. Relationship of EMAST and microsatellite instability among patients with rectal cancer. J Gastrointest Surg. 2010 Oct; 14(10):1521-8. PMID: 20844976; PMCID: PMC2943582.
    47. Horgan S, Mintz Y, Jacobsen GR, Sandler BJ, Cullen JP, Spivack A, Easter DW, Chock A, Savu MK, Ramamoorthy S, Bosia J, Agarwal S, Lukacz E, Whitcomb E, Savides T, Talamini MA. Video. Magnetic retraction for NOTES transvaginal cholecystectomy. Surg Endosc. 2010 Sep; 24(9):2322. PMID: 20177916.
      View in: PubMed
    48. Potenza B, Deligencia M, Estigoy B, Faraday E, Snyder A, Angle N, Schwartz A, Chang L, Hackett J, Minokadeh A, Madani M, MacAulay K, Ramamoorthy S, Blaner L, James C, Bansal V, Torriani F, Coimbra R. Lessons learned from the institution of the Surgical Care Improvement Project at a teaching medical center. Am J Surg. 2009 Dec; 198(6):881-8. PMID: 19969146.
      View in: PubMed
    49. Ramamoorthy SL, Fischer LJ, Jacobsen G, Thompson K, Wong B, Spivack A, Cullen J, Talamini MA, Horgan S. Transrectal endoscopic retrorectal access (TERA): a novel NOTES approach to the peritoneal cavity. J Laparoendosc Adv Surg Tech A. 2009 Oct; 19(5):603-6. PMID: 19715485.
      View in: PubMed
    50. Ramamoorthy SL, Lee JK, Luo L, Mintz Y, Cullen J, Easter DW, Savu MK, Chock A, Carethers J, Horgan S, Talamini MA. The inflammatory response in transgastric surgery: gastric content leak leads to localized inflammatory response and higher adhesive disease. Surg Endosc. 2010 Mar; 24(3):531-5. PMID: 19688397; PMCID: PMC2821621.
    51. Ramamoorthy SL, Lee JK, Mintz Y, Cullen J, Savu MK, Easter DW, Chock A, Mittal R, Horgan S, Talamini MA. The impact of proton-pump inhibitors on intraperitoneal sepsis: a word of caution for transgastric NOTES procedures. Surg Endosc. 2010 Jan; 24(1):16-20. PMID: 19551440.
      View in: PubMed
    52. Ramamoorthy S, Donohue M, Buck M. Decreased Jun-D and myogenin expression in muscle wasting of human cachexia. Am J Physiol Endocrinol Metab. 2009 Aug; 297(2):E392-401. PMID: 19470832; PMCID: PMC2724118.
    53. Horgan S, Mintz Y, Jacobsen GR, Sandler BJ, Cullen JP, Spivack A, Easter DW, Chock A, Savu MK, Ramamoorthy S, Bosia J, Agarwal S, Lukacz E, Whitcomb E, Savides T, Talamini MA. Video. NOTES: transvaginal cholecystectomy with assisting articulating instruments. Surg Endosc. 2009 Aug; 23(8):1900. PMID: 19430835.
      View in: PubMed
    54. Horgan S, Cullen JP, Talamini MA, Mintz Y, Ferreres A, Jacobsen GR, Sandler B, Bosia J, Savides T, Easter DW, Savu MK, Ramamoorthy SL, Whitcomb E, Agarwal S, Lukacz E, Dominguez G, Ferraina P. Natural orifice surgery: initial clinical experience. Surg Endosc. 2009 Jul; 23(7):1512-8. PMID: 19343435; PMCID: PMC2695868.
    55. Bharti AR, Weidner N, Ramamoorthy S. Chronic schistosomiasis in a patient with rectal cancer. Am J Trop Med Hyg. 2009 Jan; 80(1):1-2. PMID: 19141828.
      View in: PubMed
    56. Peterson CY, Ramamoorthy S, Andrews B, Horgan S, Talamini M, Chock A. Women's positive perception of transvaginal NOTES surgery. Surg Endosc. 2009 Aug; 23(8):1770-4. PMID: 19057953.
      View in: PubMed
    57. Costantini TW, Acosta JA, Hoyt DB, Ramamoorthy S. Surgical resident and attending physician attitudes toward glucose control in the surgical patient. Am Surg. 2008 Oct; 74(10):993-6. PMID: 18942630.
      View in: PubMed
    58. Lee JK, Ghosh P, McWhorter V, Payne M, Olson R, Krinsky ML, Ramamoorthy S, Carethers JM. Evidence for colorectal sarcomatoid carcinoma arising from tubulovillous adenoma. World J Gastroenterol. 2008 Jul 21; 14(27):4389-94. PMID: 18666331; PMCID: PMC2731194.
    59. Ramamoorthy S, Luo L, Luo E, Carethers JM. Tobacco smoking and risk of recurrence for squamous cell cancer of the anus. Cancer Detect Prev. 2008; 32(2):116-20. PMID: 18639388; PMCID: PMC3427794.
    60. Mareno J, Takabe K, Bakhtar O, Ramamoorthy S. Image of the month--quiz case. Heterotopic gastric mucosa. Arch Surg. 2008 May; 143(5):513-4. PMID: 18490565.
      View in: PubMed
    61. Mintz Y, Horgan S, Savu MK, Cullen J, Chock A, Ramamoorthy S, Easter DW, Talamini MA. Hybrid natural orifice translumenal surgery (NOTES) sleeve gastrectomy: a feasibility study using an animal model. Surg Endosc. 2008 Aug; 22(8):1798-802. PMID: 18437477.
      View in: PubMed
    62. Mintz Y, Horgan S, Cullen J, Ramamoorthy S, Chock A, Savu MK, Easter DW, Talamini MA. NOTES: the hybrid technique. J Laparoendosc Adv Surg Tech A. 2007 Aug; 17(4):402-6. PMID: 17705716.
      View in: PubMed
    63. Garg J, Bakhtar OR, Ramamoorthy S. Image of the month. Perforated schistosomal appendicitis. Arch Surg. 2007 May; 142(5):487-8. PMID: 17515493.
      View in: PubMed
    64. Ramamoorthy SL, Fleshman JW. Surgical treatment of rectal cancer. Hematol Oncol Clin North Am. 2002 Aug; 16(4):927-46. PMID: 12418056.
      View in: PubMed
    65. Ramamoorthy SL, Vasquez JC, Taft PM, McGinn RF, Hye RJ. Nonoperative management of acute spontaneous renal artery dissection. Ann Vasc Surg. 2002 Mar; 16(2):157-62. PMID: 11972245.
      View in: PubMed
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