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    Sonia Ramamoorthy

    TitleProfessor Of Clinical
    SchoolUniversity of California, San Diego
    DepartmentSurgery
    Address9500 Gilman Drive #0987
    CA La Jolla 92093
    Phone858-822-6277
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      Profile
      Dr. Sonia Ramamoorthy is a surgeon who specializes in surgery of the colon and rectum. She cares for patients who have cancer of the colon, rectum, and anus, as well as benign conditions such as diverticulitis and inflammatory bowel disease. She also specializes in treating pelvic floor disorders and fecal incontinence. She is certified by both the American Board of Surgery and the American Board of Colon and Rectal Surgery.

      Dr. Ramamoorthy performs open and minimally invasive colorectal surgeries as well as all standard general surgery procedures. She has advanced training in colon and rectal surgery and has special certification in minimally invasive surgical techniques to treat cancers as well as other conditions in the colon, rectum, and anus. Dr. Ramamoorthy’s surgeries for benign conditions include laparoscopic colectomy for benign polyps, diverticular disease, inflammatory bowel disease, constipation, and prolapse.

      Dr. Ramamoorthy is active in the surgical community as an instructor who trains other surgeons to perform laparoscopic colorectal surgery.

      Dr. Ramamoorthy’s research interests include colorectal and anal cancer, Crohn’s disease and ulcerative colitis, and pelvic floor disorders. Here at UC San Diego, Dr. Ramamoorthy is part of the Translational Oncology Program at the Moores UC San Diego Cancer Center, where her ongoing research focuses on developing techniques for determining a patient’s risk of cancer recurrence after surgery for early rectal cancer.

      Dr. Ramamoorthy’s current research projects also include a study of the role of microsatellite instability (MIS) in squamous cell cancer of the anus. Squamous cell cancer of the anus is becoming more common in the United States, particularly in individuals who are immunocompromised and those who are HIV/HPV-positive. Her research is supported by a grant from the American Cancer Society.

      Dr. Ramamoorthy speaks English and some Spanish.


      Collapse Research 
      Collapse Research Activities and Funding
      1/2 SDSU/UCSD Cancer Center Comprehensive Partnership
      NIH/NCI U54CA132379Dec 1, 2007 - Aug 31, 2020
      Role: Co-Investigator

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      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Cosman BC, Cajas-Monson LC, Ramamoorthy S. Twenty Years of a Veterans' Spinal Cord Injury Colorectal Clinic: Flexible Sigmoidoscopy and Multiple Hemorrhoid Ligation. Dis Colon Rectum. 2017 Apr; 60(4):399-404. PMID: 28267007.
        View in: PubMed
      2. Fumery M, Dulai PS, Gupta S, Prokop LJ, Ramamoorthy S, Sandborn WJ, Singh S. Incidence, Risk Factors, and Outcomes of Colorectal Cancer in Patients With Ulcerative Colitis With Low-Grade Dysplasia: A Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol. 2017 May; 15(5):665-674.e5. PMID: 27916678.
        View in: PubMed
      3. Singh S, Dulai PS, Zarrinpar A, Ramamoorthy S, Sandborn WJ. Obesity in IBD: epidemiology, pathogenesis, disease course and treatment outcomes. Nat Rev Gastroenterol Hepatol. 2017 Feb; 14(2):110-121. PMID: 27899815.
        View in: PubMed
      4. Hu WH, Chen HH, Lee KC, Liu L, Eisenstein S, Parry L, Cosman B, Ramamoorthy S. Assessment of the Addition of Hypoalbuminemia to ACS-NSQIP Surgical Risk Calculator in Colorectal Cancer. Medicine (Baltimore). 2016 Mar; 95(10):e2999. PMID: 26962812; PMCID: PMC4998893.
      5. Hu WH, Miyai K, Sporn JC, Luo L, Wang JY, Cosman B, Ramamoorthy S. Loss of histone variant macroH2A2 expression associates with progression of anal neoplasm. J Clin Pathol. 2016 Jul; 69(7):627-31. PMID: 26658220; PMCID: PMC4941135.
      6. Hu WH, Cajas-Monson LC, Eisenstein S, Parry L, Cosman B, Ramamoorthy S. Preoperative malnutrition assessments as predictors of postoperative mortality and morbidity in colorectal cancer: an analysis of ACS-NSQIP. Nutr J. 2015 Sep 07; 14:91. PMID: 26345703; PMCID: PMC4561437.
      7. Hu WH, Miyai K, Cajas-Monson LC, Luo L, Liu L, Ramamoorthy S. Tumor-infiltrating CD8(+) T lymphocytes associated with clinical outcome in anal squamous cell carcinoma. J Surg Oncol. 2015 Sep; 112(4):421-6. PMID: 26287957.
        View in: PubMed
      8. Hu WH, Cajas-Monson LC, Eisenstein S, Parry L, Ramamoorthy S. Association of dialysis with adverse postoperative outcomes in colorectal cancer-an analysis of ACS-NSQIP. Int J Colorectal Dis. 2015 Nov; 30(11):1557-62. PMID: 26243472.
        View in: PubMed
      9. Lopez NE, Peterson CY, Ramamoorthy S, McLemore EC, Sedrak MF, Lowy AM, Horgan S, Talamini MA, Sicklick JK. Single-incision laparoscopic surgery through an ostomy site: a natural approach by an unnatural orifice. Surg Laparosc Endosc Percutan Tech. 2015 Feb; 25(1):74-8. PMID: 24743670.
        View in: PubMed
      10. Fuchs HF, Broderick RC, Harnsberger CR, Chang DC, Mclemore EC, Ramamoorthy S, Horgan S. Variation of outcome and charges in operative management for diverticulitis. Surg Endosc. 2015 Nov; 29(11):3090-6. PMID: 25539698.
        View in: PubMed
      11. Broderick RC, Fuchs HF, Harnsberger CR, Chang DC, McLemore E, Ramamoorthy S, Horgan S. The price of decreased mortality in the operative management of diverticulitis. Surg Endosc. 2015 May; 29(5):1185-91. PMID: 25159639.
        View in: PubMed
      12. Ward NT, Ramamoorthy S, Chang DC, Parsons JK. Laparoscopic appendectomy is safer than open appendectomy in an elderly population. JSLS. 2014 Jul-Sep; 18(3). PMID: 25392668; PMCID: PMC4208904.
      13. Weiss A, Lee KC, Tapia V, Chang D, Freischlag J, Blair SL, Ramamoorthy S. Equity in surgical leadership for women: more work to do. Am J Surg. 2014 Sep; 208(3):494-8. PMID: 24933664.
        View in: PubMed
      14. McLemore EC, Weston LA, Coker AM, Jacobsen GR, Talamini MA, Horgan S, Ramamoorthy S. Transanal minimally invasive surgery for benign and malignant rectal neoplasia. Am J Surg. 2014 Sep; 208(3):372-81. PMID: 24832238.
        View in: PubMed
      15. Viscusi ER, Sinatra R, Onel E, Ramamoorthy S. The safety of liposome bupivacaine, a novel local analgesic formulation. Clin J Pain. 2014 Feb; 30(2):102-10. PMID: 23446090.
        View in: PubMed
      16. Simpson DR, Martínez ME, Gupta S, Hattangadi-Gluth J, Mell LK, Heestand G, Fanta P, Ramamoorthy S, Le QT, Murphy JD. Racial disparity in consultation, treatment, and the impact on survival in metastatic colorectal cancer. J Natl Cancer Inst. 2013 Dec 04; 105(23):1814-20. PMID: 24231453; PMCID: PMC4383284.
      17. Peterson CY, Palazzi K, Parsons JK, Chang DC, Ramamoorthy S. The prevalence of laparoscopy and patient safety outcomes: an analysis of colorectal resections. Surg Endosc. 2014 Feb; 28(2):608-16. PMID: 24091552.
        View in: PubMed
      18. Metildi C, McLemore EC, Tran T, Chang D, Cosman B, Ramamoorthy S, Saltzstein SL, Sadler GR. Incidence and survival patterns of rare anal canal neoplasms using the surveillance epidemiology and end results registry. Am Surg. 2013 Oct; 79(10):1068-74. PMID: 24160801; PMCID: PMC4209843.
      19. Bazzi WM, Stroup SP, Cohen SA, Sisul DM, Liss MA, Masterson JH, Kopp RP, Gudeman SR, Leeflang E, Palazzi KL, Ramamoorthy S, Kane CJ, Horgan S, Derweesh IH. Comparison of transrectal and transvaginal hybrid natural orifice transluminal endoscopic surgery partial nephrectomy in the porcine model. Urology. 2013 Jul; 82(1):84-9. PMID: 23676357.
        View in: PubMed
      20. McLemore EC, Coker AM, Devaraj B, Chakedis J, Maawy A, Inui T, Talamini MA, Horgan S, Peterson MR, Sylla P, Ramamoorthy S. TAMIS-assisted laparoscopic low anterior resection with total mesorectal excision in a cadaveric series. Surg Endosc. 2013 Sep; 27(9):3478-84. PMID: 23494511; PMCID: PMC4343257.
      21. Horgan S, Meireles OR, Jacobsen GR, Sandler BJ, Ferreres A, Ramamoorthy S, Savides T, Katagiri T, Dotai T, Sedrak M, Majid SF, Nijhawan S, Talamini MA. Broad clinical utilization of NOTES: is it safe? Surg Endosc. 2013 Jun; 27(6):1872-80. PMID: 23479251.
        View in: PubMed
      22. Ramamoorthy S, Obias V. Unique complications of robotic colorectal surgery. Surg Clin North Am. 2013 Feb; 93(1):273-86. PMID: 23177076.
        View in: PubMed
      23. Bazzi WM, Stroup SP, Cohen SA, Dotai T, Kopp RP, Colangelo C, Raheem OA, Ramamoorthy S, Talamini M, Horgan S, Kane CJ, Derweesh IH. Feasibility of transrectal hybrid natural orifice transluminal endoscopic surgery (NOTES) nephrectomy in the cadaveric model. Urology. 2012 Sep; 80(3):590-5. PMID: 22925236.
        View in: PubMed
      24. Pola S, Patel D, Ramamoorthy S, McLemore E, Fahmy M, Rivera-Nieves J, Chang JT, Evans E, Docherty M, Talamini M, Sandborn WJ. Strategies for the care of adults hospitalized for active ulcerative colitis. Clin Gastroenterol Hepatol. 2012 Dec; 10(12):1315-1325.e4. PMID: 22835577; PMCID: PMC4226798.
      25. Peterson CY, McLemore EC, Horgan S, Talamini MA, Ramamoorthy S. Technical aspects of robotic proctectomy. Surg Laparosc Endosc Percutan Tech. 2012 Jun; 22(3):189-93. PMID: 22678311.
        View in: PubMed
      26. McLemore EC, Ramamoorthy S, Peterson CY, Bass BL. Women in surgery: bright, sharp, brave, and temperate. Perm J. 2012; 16(3):54-9. PMID: 23012600; PMCID: PMC3442763.
      27. McLemore EC, Cullen J, Horgan S, Talamini MA, Ramamoorthy S. Robotic-assisted laparoscopic stage II restorative proctectomy for toxic ulcerative colitis. Int J Med Robot. 2012 Jun; 8(2):178-83. PMID: 22113993.
        View in: PubMed
      28. Rajasekaran MR, Jiang Y, Bhargava V, Ramamoorthy S, Lieber RL, Mittal RK. Sustained improvement in the anal sphincter function following surgical plication of rabbit external anal sphincter muscle. Dis Colon Rectum. 2011 Nov; 54(11):1373-80. PMID: 21979181.
        View in: PubMed
      29. Bazzi WM, Wagner O, Stroup SP, Silberstein JL, Belkind N, Katagiri T, Paleari J, Duro A, Ramamoorthy S, Talamini MA, Horgan S, Derweesh IH. Transrectal hybrid natural orifice transluminal endoscopic surgery (NOTES) nephrectomy in a porcine model. Urology. 2011 Mar; 77(3):518-23. PMID: 21376997.
        View in: PubMed
      30. Ramamoorthy S, Devaraj B, Miyai K, Luo L, Liu YT, Boland CR, Goel A, Carethers JM. John Cunningham virus T-antigen expression in anal carcinoma. Cancer. 2011 Jun 01; 117(11):2379-85. PMID: 24048785; PMCID: PMC3060305.
      31. Ramamoorthy S, Liu YT, Luo L, Miyai K, Lu Q, Carethers JM. Detection of multiple human papillomavirus genotypes in anal carcinoma. Infect Agent Cancer. 2010 Oct 12; 5:17. PMID: 20939896; PMCID: PMC2964599.
      32. Dong H, Shim KN, Li JM, Estrema C, Ornelas TA, Nguyen F, Liu S, Ramamoorthy S, Ho S, Carethers JM, Chow JY. Molecular mechanisms underlying Ca2+-mediated motility of human pancreatic duct cells. Am J Physiol Cell Physiol. 2010 Dec; 299(6):C1493-503. PMID: 20861471; PMCID: PMC3006328.
      33. Devaraj B, Lee A, Cabrera BL, Miyai K, Luo L, Ramamoorthy S, Keku T, Sandler RS, McGuire KL, Carethers JM. Relationship of EMAST and microsatellite instability among patients with rectal cancer. J Gastrointest Surg. 2010 Oct; 14(10):1521-8. PMID: 20844976; PMCID: PMC2943582.
      34. Horgan S, Mintz Y, Jacobsen GR, Sandler BJ, Cullen JP, Spivack A, Easter DW, Chock A, Savu MK, Ramamoorthy S, Bosia J, Agarwal S, Lukacz E, Whitcomb E, Savides T, Talamini MA. Video. Magnetic retraction for NOTES transvaginal cholecystectomy. Surg Endosc. 2010 Sep; 24(9):2322. PMID: 20177916.
        View in: PubMed
      35. Potenza B, Deligencia M, Estigoy B, Faraday E, Snyder A, Angle N, Schwartz A, Chang L, Hackett J, Minokadeh A, Madani M, MacAulay K, Ramamoorthy S, Blaner L, James C, Bansal V, Torriani F, Coimbra R. Lessons learned from the institution of the Surgical Care Improvement Project at a teaching medical center. Am J Surg. 2009 Dec; 198(6):881-8. PMID: 19969146.
        View in: PubMed
      36. Ramamoorthy S, Fischer LJ, Jacobsen G, Thompson K, Wong B, Spivack A, Cullen J, Talamini MA, Horgan S. Transrectal endoscopic retrorectal access (TERA): a novel NOTES approach to the peritoneal cavity. J Laparoendosc Adv Surg Tech A. 2009 Oct; 19(5):603-6. PMID: 19715485.
        View in: PubMed
      37. Ramamoorthy S, Lee JK, Luo L, Mintz Y, Cullen J, Easter DW, Savu MK, Chock A, Carethers J, Horgan S, Talamini MA. The inflammatory response in transgastric surgery: gastric content leak leads to localized inflammatory response and higher adhesive disease. Surg Endosc. 2010 Mar; 24(3):531-5. PMID: 19688397; PMCID: PMC2821621.
      38. Ramamoorthy S, Lee JK, Mintz Y, Cullen J, Savu MK, Easter DW, Chock A, Mittal R, Horgan S, Talamini MA. The impact of proton-pump inhibitors on intraperitoneal sepsis: a word of caution for transgastric NOTES procedures. Surg Endosc. 2010 Jan; 24(1):16-20. PMID: 19551440.
        View in: PubMed
      39. Ramamoorthy S, Donohue M, Buck M. Decreased Jun-D and myogenin expression in muscle wasting of human cachexia. Am J Physiol Endocrinol Metab. 2009 Aug; 297(2):E392-401. PMID: 19470832; PMCID: PMC2724118.
      40. Horgan S, Mintz Y, Jacobsen GR, Sandler BJ, Cullen JP, Spivack A, Easter DW, Chock A, Savu MK, Ramamoorthy S, Bosia J, Agarwal S, Lukacz E, Whitcomb E, Savides T, Talamini MA. Video. NOTES: transvaginal cholecystectomy with assisting articulating instruments. Surg Endosc. 2009 Aug; 23(8):1900. PMID: 19430835.
        View in: PubMed
      41. Horgan S, Cullen JP, Talamini MA, Mintz Y, Ferreres A, Jacobsen GR, Sandler B, Bosia J, Savides T, Easter DW, Savu MK, Ramamoorthy S, Whitcomb E, Agarwal S, Lukacz E, Dominguez G, Ferraina P. Natural orifice surgery: initial clinical experience. Surg Endosc. 2009 Jul; 23(7):1512-8. PMID: 19343435; PMCID: PMC2695868.
      42. Bharti AR, Weidner N, Ramamoorthy S. Chronic schistosomiasis in a patient with rectal cancer. Am J Trop Med Hyg. 2009 Jan; 80(1):1-2. PMID: 19141828.
        View in: PubMed
      43. Peterson CY, Ramamoorthy S, Andrews B, Horgan S, Talamini M, Chock A. Women's positive perception of transvaginal NOTES surgery. Surg Endosc. 2009 Aug; 23(8):1770-4. PMID: 19057953.
        View in: PubMed
      44. Costantini TW, Acosta JA, Hoyt DB, Ramamoorthy S. Surgical resident and attending physician attitudes toward glucose control in the surgical patient. Am Surg. 2008 Oct; 74(10):993-6. PMID: 18942630.
        View in: PubMed
      45. Lee JK, Ghosh P, McWhorter V, Payne M, Olson R, Krinsky ML, Ramamoorthy S, Carethers JM. Evidence for colorectal sarcomatoid carcinoma arising from tubulovillous adenoma. World J Gastroenterol. 2008 Jul 21; 14(27):4389-94. PMID: 18666331; PMCID: PMC2731194.
      46. Ramamoorthy S, Luo L, Luo E, Carethers JM. Tobacco smoking and risk of recurrence for squamous cell cancer of the anus. Cancer Detect Prev. 2008; 32(2):116-20. PMID: 18639388; PMCID: PMC3427794.
      47. Mareno J, Takabe K, Bakhtar O, Ramamoorthy S. Image of the month--quiz case. Heterotopic gastric mucosa. Arch Surg. 2008 May; 143(5):513-4. PMID: 18490565.
        View in: PubMed
      48. Mintz Y, Horgan S, Savu MK, Cullen J, Chock A, Ramamoorthy S, Easter DW, Talamini MA. Hybrid natural orifice translumenal surgery (NOTES) sleeve gastrectomy: a feasibility study using an animal model. Surg Endosc. 2008 Aug; 22(8):1798-802. PMID: 18437477.
        View in: PubMed
      49. Mintz Y, Horgan S, Cullen J, Ramamoorthy S, Chock A, Savu MK, Easter DW, Talamini MA. NOTES: the hybrid technique. J Laparoendosc Adv Surg Tech A. 2007 Aug; 17(4):402-6. PMID: 17705716.
        View in: PubMed
      50. Garg J, Bakhtar OR, Ramamoorthy S. Image of the month. Perforated schistosomal appendicitis. Arch Surg. 2007 May; 142(5):487-8. PMID: 17515493.
        View in: PubMed
      51. Ramamoorthy S, Vasquez JC, Taft PM, McGinn RF, Hye RJ. Nonoperative management of acute spontaneous renal artery dissection. Ann Vasc Surg. 2002 Mar; 16(2):157-62. PMID: 11972245.
        View in: PubMed