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Metatranscriptomics Uncover Diurnal Functional Shifts in Bacterial Transgenes with Profound Metabolic Effects. Cell Host Microbe. 2025 Jul 09; 33(7):1057-1072.
Ramos SF, Siguenza N, Zhong W, Mohanty I, Lingaraju A, Richter RA, Karthikeyan S, Lukowski AL, Zhu Q, Nunes WDG, Zemlin J, Xu ZZ, Hasty J, Dorrestein PC, Panda S, Knight R, Zarrinpar A. PMID: 40777923; PMCID: PMC12327816.
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AnimalsCells
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Mind over microbiota: neurons call the shots in the gut. Nat Metab. 2025 Jun; 7(6):1100-1102.
Zhong W, Wang K, Zarrinpar A. PMID: 40263604.
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Taurultam shows antiviral activity against SARS-CoV-2 and influenza virus. BMC Microbiol. 2025 May 15; 25(1):292.
Luo R, Shen B, Qian B, Fan L, Zhang J, Deng X, Sun Y, Zhang S, Wang T, Li Y, Sun W, Pang X, Zhong W, Gao Y. PMID: 40375181; PMCID: PMC12080262.
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HumansAnimalsCells
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Chemical cross-linking facilitates antigen uptake and presentation and provides improved protection from Mpox with a dual-antigen subunit vaccine. MedComm (2020). 2025 Jan; 6(1):e70045.
Chen L, Shang C, Wang Z, Zheng M, Zhang C, Li D, Yang Z, Dong Y, Xu Y, Yuan Y, Fan S, Zhong W, Lin J, Li X. PMID: 39781294; PMCID: PMC11707423.
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PubMed Mentions:
1
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In vitro and in vivo inhibition of the host TRPC4 channel attenuates Zika virus infection. EMBO Mol Med. 2024 Aug; 16(8):1817-1839.
Chen X, Yan Y, Liu Z, Yang S, Li W, Wang Z, Wang M, Guo J, Li Z, Zhu W, Yang J, Yin J, Dai Q, Li Y, Wang C, Zhao L, Yang X, Guo X, Leng L, Xu J, Obukhov AG, Cao R, Zhong W. PMID: 39009885; PMCID: PMC11319825.
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PubMed Mentions:
2 Fields:
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HumansAnimalsCells
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Discovery of baloxavir sodium as a novel anti-CCHFV inhibitor: Biological evaluation of in vitro and in vivo. Antiviral Res. 2024 07; 227:105890.
Liu K, Li L, Liu Y, Wang X, Liu J, Li J, Deng F, Zhang R, Zhou Y, Hu Z, Zhong W, Wang M, Guo C. PMID: 38657838.
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2 Fields:
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HumansAnimalsCells
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Efficacy of small molecules against the severe acute respiratory syndrome coronavirus 2 XBB1.16 and XBB1.9.2.1. MedComm (2020). 2024 Mar; 5(3):e500.
Yuan L, Liu X, Li S, Zhong W, Xia N. PMID: 38420159; PMCID: PMC10901279.
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Author Correction: Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials. Nat Commun. 2024 Feb 05; 15(1):1075.
Axfors C, Schmitt AM, Janiaud P, Van't Hooft J, Abd-Elsalam S, Abdo EF, Abella BS, Akram J, Amaravadi RK, Angus DC, Arabi YM, Azhar S, Baden LR, Baker AW, Belkhir L, Benfield T, Berrevoets MAH, Chen CP, Chen TC, Cheng SH, Cheng CY, Chung WS, Cohen YZ, Cowan LN, Dalgard O, de Almeida E Val FF, de Lacerda MVG, de Melo GC, Derde L, Dubee V, Elfakir A, Gordon AC, Hernandez-Cardenas CM, Hills T, Hoepelman AIM, Huang YW, Igau B, Jin R, Jurado-Camacho F, Khan KS, Kremsner PG, Kreuels B, Kuo CY, Le T, Lin YC, Lin WP, Lin TH, Lyngbakken MN, McArthur C, McVerry BJ, Meza-Meneses P, Monteiro WM, Morpeth SC, Mourad A, Mulligan MJ, Murthy S, Naggie S, Narayanasamy S, Nichol A, Novack LA, O'Brien SM, Okeke NL, Perez L, Perez-Padilla R, Perrin L, Remigio-Luna A, Rivera-Martinez NE, Rockhold FW, Rodriguez-Llamazares S, Rolfe R, Rosa R, Røsjø H, Sampaio VS, Seto TB, Shahzad M, Soliman S, Stout JE, Thirion-Romero I, Troxel AB, Tseng TY, Turner NA, Ulrich RJ, Walsh SR, Webb SA, Weehuizen JM, Velinova M, Wong HL, Wrenn R, Zampieri FG, Zhong W, Moher D, Goodman SN, Ioannidis JPA, Hemkens LG. PMID: 38316844; PMCID: PMC10844287.
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1 Fields:
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Effect of enzymatic Maillard reaction conditions on physicochemical properties, nutrition, fatty acids composition and key aroma compounds of fragrant rapeseed oil. J Sci Food Agric. 2024 Mar 15; 104(4):1953-1961.
Huang H, Chu B, Yuan Q, Gao P, Zhong W, Yin J, Hu C, He D, Jiang X, Wang X. PMID: 37897493.
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3 Fields:
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Direct inhibition of dioxygenases TET1 by the rheumatoid arthritis drug auranofin selectively induces cancer cell death in T-ALL. J Hematol Oncol. 2023 11 22; 16(1):113.
Chen L, Ren A, Zhao Y, Chen H, Wu Q, Zheng M, Zhang Z, Zhang T, Zhong W, Lin J, Zhu H. PMID: 37993905; PMCID: PMC10666452.
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PubMed Mentions:
6 Fields:
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HumansCells
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Multi-valent mRNA vaccines against monkeypox enveloped or mature viron surface antigens demonstrate robust immune response and neutralizing activity. Sci China Life Sci. 2023 10; 66(10):2329-2341.
Zhang N, Cheng X, Zhu Y, Mo O, Yu H, Zhu L, Zhang J, Kuang L, Gao Y, Cao R, Liang X, Wang H, Li H, Li S, Zhong W, Li X, Li X, Hao P. PMID: 37300753; PMCID: PMC10257374.
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PubMed Mentions:
26 Fields:
Translation:
AnimalsCells
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Discovery and Optimization of Quinoline Analogues as Novel Potent Antivirals against Enterovirus D68. J Med Chem. 2022 11 10; 65(21):14792-14808.
Li X, Li Y, Fan S, Cao R, Li X, He X, Li W, Xu L, Cheng T, Li H, Zhong W. PMID: 36254462; PMCID: PMC9661475.
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PubMed Mentions:
3 Fields:
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HumansAnimalsCells
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LDL receptor-related protein 1 (LRP1), a novel target for opening the blood-labyrinth barrier (BLB). Signal Transduct Target Ther. 2022 06 10; 7(1):175.
Shi X, Wang Z, Ren W, Chen L, Xu C, Li M, Fan S, Xu Y, Chen M, Zheng F, Zhang W, Zhou X, Zhang Y, Qiu S, Wu L, Zhou P, Lv X, Cui T, Qiao Y, Zhao H, Guo W, Chen W, Li S, Zhong W, Lin J, Yang S. PMID: 35680846; PMCID: PMC9184653.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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Characteristics and Antioxidant Activity of Walnut Oil Using Various Pretreatment and Processing Technologies. Foods. 2022 Jun 09; 11(12).
Gao P, Ding Y, Chen Z, Zhou Z, Zhong W, Hu C, He D, Wang X. PMID: 35741896; PMCID: PMC9222277.
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PubMed Mentions:
10
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In vitro and in vivo efficacy of a novel nucleoside analog H44 against Crimean-Congo hemorrhagic fever virus. Antiviral Res. 2022 03; 199:105273.
Wang Q, Cao R, Li L, Liu J, Yang J, Li W, Yan L, Wang Y, Yan Y, Li J, Deng F, Zhou Y, Wang M, Zhong W, Hu Z. PMID: 35257725.
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PubMed Mentions:
8 Fields:
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AnimalsCells
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Morinda officinalis oligosaccharides increase serotonin in the brain and ameliorate depression via promoting 5-hydroxytryptophan production in the gut microbiota. Acta Pharm Sin B. 2022 Aug; 12(8):3298-3312.
Zhang ZW, Gao CS, Zhang H, Yang J, Wang YP, Pan LB, Yu H, He CY, Luo HB, Zhao ZX, Zhou XB, Wang YL, Fu J, Han P, Dong YH, Wang G, Li S, Wang Y, Jiang JD, Zhong W. PMID: 35967282; PMCID: PMC9366226.
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42
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Sera proteomic features of active and recovered COVID-19 patients: potential diagnostic and prognostic biomarkers. Signal Transduct Target Ther. 2021 06 03; 6(1):216.
Leng L, Li M, Li W, Mou D, Liu G, Ma J, Zhang S, Li H, Cao R, Zhong W. PMID: 34083512; PMCID: PMC8173321.
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PubMed Mentions:
14 Fields:
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HumansCells
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Author Correction: Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials. Nat Commun. 2021 May 14; 12(1):3001.
Axfors C, Schmitt AM, Janiaud P, Van't Hooft J, Abd-Elsalam S, Abdo EF, Abella BS, Akram J, Amaravadi RK, Angus DC, Arabi YM, Azhar S, Baden LR, Baker AW, Belkhir L, Benfield T, Berrevoets MAH, Chen CP, Chen TC, Cheng SH, Cheng CY, Chung WS, Cohen YZ, Cowan LN, Dalgard O, de Almeida E Val FF, de Lacerda MVG, de Melo GC, Derde L, Dubee V, Elfakir A, Gordon AC, Hernandez-Cardenas CM, Hills T, Hoepelman AIM, Huang YW, Igau B, Jin R, Jurado-Camacho F, Khan KS, Kremsner PG, Kreuels B, Kuo CY, Le T, Lin YC, Lin WP, Lin TH, Lyngbakken MN, McArthur C, McVerry BJ, Meza-Meneses P, Monteiro WM, Morpeth SC, Mourad A, Mulligan MJ, Murthy S, Naggie S, Narayanasamy S, Nichol A, Novack LA, O'Brien SM, Okeke NL, Perez L, Perez-Padilla R, Perrin L, Remigio-Luna A, Rivera-Martinez NE, Rockhold FW, Rodriguez-Llamazares S, Rolfe R, Rosa R, Røsjø H, Sampaio VS, Seto TB, Shahzad M, Soliman S, Stout JE, Thirion-Romero I, Troxel AB, Tseng TY, Turner NA, Ulrich RJ, Walsh SR, Webb SA, Weehuizen JM, Velinova M, Wong HL, Wrenn R, Zampieri FG, Zhong W, Moher D, Goodman SN, Ioannidis JPA, Hemkens LG. PMID: 33990619; PMCID: PMC8121133.
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PubMed Mentions:
6 Fields:
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Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials. Nat Commun. 2021 04 15; 12(1):2349.
Axfors C, Schmitt AM, Janiaud P, Van't Hooft J, Abd-Elsalam S, Abdo EF, Abella BS, Akram J, Amaravadi RK, Angus DC, Arabi YM, Azhar S, Baden LR, Baker AW, Belkhir L, Benfield T, Berrevoets MAH, Chen CP, Chen TC, Cheng SH, Cheng CY, Chung WS, Cohen YZ, Cowan LN, Dalgard O, de Almeida E Val FF, de Lacerda MVG, de Melo GC, Derde L, Dubee V, Elfakir A, Gordon AC, Hernandez-Cardenas CM, Hills T, Hoepelman AIM, Huang YW, Igau B, Jin R, Jurado-Camacho F, Khan KS, Kremsner PG, Kreuels B, Kuo CY, Le T, Lin YC, Lin WP, Lin TH, Lyngbakken MN, McArthur C, McVerry BJ, Meza-Meneses P, Monteiro WM, Morpeth SC, Mourad A, Mulligan MJ, Murthy S, Naggie S, Narayanasamy S, Nichol A, Novack LA, O'Brien SM, Okeke NL, Perez L, Perez-Padilla R, Perrin L, Remigio-Luna A, Rivera-Martinez NE, Rockhold FW, Rodriguez-Llamazares S, Rolfe R, Rosa R, Røsjø H, Sampaio VS, Seto TB, Shahzad M, Soliman S, Stout JE, Thirion-Romero I, Troxel AB, Tseng TY, Turner NA, Ulrich RJ, Walsh SR, Webb SA, Weehuizen JM, Velinova M, Wong HL, Wrenn R, Zampieri FG, Zhong W, Moher D, Goodman SN, Ioannidis JPA, Hemkens LG. PMID: 33859192; PMCID: PMC8050319.
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PubMed Mentions:
168 Fields:
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HumansCells
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Metal-Protein Nanoparticles Facilitate Anti-VSV and H1N1 Viruses Through the Coordinative Actions on Innate Immune Responses and METTL14. Macromol Biosci. 2021 04; 21(4):e2000382.
Zhu XJ, Feng JQ, Zheng MZ, Yang ZR, Zhao L, Zhang W, Zhong W, Chen YY, Lin J. PMID: 33522144.
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PubMed Mentions:
12 Fields:
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HumansAnimalsCells
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Pathological features of COVID-19-associated liver injury-a preliminary proteomics report based on clinical samples. Signal Transduct Target Ther. 2021 01 08; 6(1):9.
Leng L, Cao R, Ma J, Lv L, Li W, Zhu Y, Wu Z, Wang M, Zhou Y, Zhong W. PMID: 33419962; PMCID: PMC7791959.
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PubMed Mentions:
13 Fields:
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Pathological features of COVID-19-associated lung injury: a preliminary proteomics report based on clinical samples. Signal Transduct Target Ther. 2020 10 15; 5(1):240.
Leng L, Cao R, Ma J, Mou D, Zhu Y, Li W, Lv L, Gao D, Zhang S, Gong F, Zhao L, Qiu B, Xiang H, Hu Z, Feng Y, Dai Y, Zhao J, Wu Z, Li H, Zhong W. PMID: 33060566; PMCID: PMC7557250.
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PubMed Mentions:
95 Fields:
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HumansCellsPHPublic Health
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Molecular simulation of SARS-CoV-2 spike protein binding to pangolin ACE2 or human ACE2 natural variants reveals altered susceptibility to infection. J Gen Virol. 2020 09; 101(9):921-924.
Wang J, Xu X, Zhou X, Chen P, Liang H, Li X, Zhong W, Hao P. PMID: 32538738; PMCID: PMC7654750.
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PubMed Mentions:
33 Fields:
Translation:
HumansAnimalsPHPublic Health
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Improvement of the C-glycosylation Step for the Synthesis of Remdesivir. Org Process Res Dev. 2020 Sep 18; 24(9):1772-1777.
Xue F, Zhou X, Zhou R, Zhou X, Xiao D, Gu E, Guo X, Xiang J, Wang K, Yang L, Zhong W, Qin Y. PMID: 37556261.
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PubMed Mentions:
12
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Development of Novel Anti-influenza Thiazolides with Relatively Broad-Spectrum Antiviral Potentials. Antimicrob Agents Chemother. 2020 06 23; 64(7).
Zhao L, Yan Y, Dai Q, Li X, Xu K, Zou G, Yang K, Li W, Guo X, Yang J, Li Y, Xia Q, Cao R, Zhong W. PMID: 32312780; PMCID: PMC7318005.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods. Acta Pharm Sin B. 2020 May; 10(5):766-788.
Wu C, Liu Y, Yang Y, Zhang P, Zhong W, Wang Y, Wang Q, Xu Y, Li M, Li X, Zheng M, Chen L, Li H. PMID: 32292689; PMCID: PMC7102550.
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PubMed Mentions:
1033
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Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission. Sci China Life Sci. 2020 03; 63(3):457-460.
Xu X, Chen P, Wang J, Feng J, Zhou H, Li X, Zhong W, Hao P. PMID: 32009228; PMCID: PMC7089049.
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PubMed Mentions:
1031 Fields:
Translation:
HumansCellsPHPublic Health
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Rapid Neutralization Testing System for Zika Virus Based on an Enzyme-Linked Immunospot Assay. ACS Infect Dis. 2020 05 08; 6(5):811-819.
Li S, Zhao H, Yang H, Hou W, Cruz-Cosme R, Cao R, Chen C, Wang W, Xu L, Zhang J, Zhong W, Xia N, Tang Q, Cheng T. PMID: 31840495.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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A Novel Self-Assembled Mitochondria-Targeting Protein Nanoparticle Acting as Theranostic Platform for Cancer. Small. 2019 01; 15(2):e1803428.
Zhu XJ, Li RF, Xu L, Yin H, Chen L, Yuan Y, Zhong W, Lin J. PMID: 30450734.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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De Novo Design of α-Helical Lipopeptides Targeting Viral Fusion Proteins: A Promising Strategy for Relatively Broad-Spectrum Antiviral Drug Discovery. J Med Chem. 2018 10 11; 61(19):8734-8745.
Wang C, Zhao L, Xia S, Zhang T, Cao R, Liang G, Li Y, Meng G, Wang W, Shi W, Zhong W, Jiang S, Liu K. PMID: 30192544; PMCID: PMC7075651.
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PubMed Mentions:
33 Fields:
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HumansCells
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A comprehensive study on cellular RNA editing activity in response to infections with different subtypes of influenza a viruses. BMC Genomics. 2018 01 19; 19(Suppl 1):925.
Cao Y, Cao R, Huang Y, Zhou H, Liu Y, Li X, Zhong W, Hao P. PMID: 29363430; PMCID: PMC5780764.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
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A survey on cellular RNA editing activity in response to Candida albicans infections. BMC Genomics. 2018 01 19; 19(Suppl 1):43.
Huang Y, Cao Y, Li J, Liu Y, Zhong W, Li X, Chen C, Hao P. PMID: 29363428; PMCID: PMC5780849.
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PubMed Mentions:
3 Fields:
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HumansAnimalsCells
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Differential responses of innate immunity triggered by different subtypes of influenza a viruses in human and avian hosts. BMC Med Genomics. 2017 12 21; 10(Suppl 4):70.
Cao Y, Huang Y, Xu K, Liu Y, Li X, Xu Y, Zhong W, Hao P. PMID: 29322931; PMCID: PMC5763291.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimalsCells
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Identification and biochemical characterization of DC07090 as a novel potent small molecule inhibitor against human enterovirus 71 3C protease by structure-based virtual screening. Eur J Med Chem. 2016 Nov 29; 124:981-991.
Ma GH, Ye Y, Zhang D, Xu X, Si P, Peng JL, Xiao YL, Cao RY, Yin YL, Chen J, Zhao LX, Zhou Y, Zhong W, Liu H, Luo XM, Chen LL, Shen X. PMID: 27776325.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Compound 331 selectively induces glioma cell death by upregulating miR-494 and downregulating CDC20. Sci Rep. 2015 Jul 08; 5:12003.
Zhang L, Niu T, Huang Y, Zhu H, Zhong W, Lin J, Zhang Y. PMID: 26153143; PMCID: PMC4495416.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells