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The TRPA1 ion channel is expressed in CD4+ T cells and restrains T-cell-mediated colitis through inhibition of TRPV1. Gut. 2017 09; 66(9):1584-1596.
Bertin S, Aoki-Nonaka Y, Lee J, de Jong PR, Kim P, Han T, Yu T, To K, Takahashi N, Boland BS, Chang JT, Ho SB, Herdman S, Corr M, Franco A, Sharma S, Dong H, Akopian AN, Raz E. PMID: 27325418.
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ERK5 signalling rescues intestinal epithelial turnover and tumour cell proliferation upon ERK1/2 abrogation. Nat Commun. 2016 05 17; 7:11551.
de Jong PR, Taniguchi K, Harris AR, Bertin S, Takahashi N, Duong J, Campos AD, Powis G, Corr M, Karin M, Raz E. PMID: 27187615.
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20 Fields:
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Transient Receptor Potential (TRP) channels in T cells. Semin Immunopathol. 2016 05; 38(3):309-19.
Bertin S, Raz E. PMID: 26468011.
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13 Fields:
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[A novel role for the TRPV1 ion channel in CD4 T cell activation]. Med Sci (Paris). 2015 Feb; 31(2):135-6.
Bertin S, Raz E. PMID: 25744258.
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TRPV1: Turning up the heat on intestinal tumorigenesis. Mol Cell Oncol. 2015 Jan-Mar; 2(1):e975619.
de Jong PR, Bertin S, Raz E. PMID: 27308393.
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The ion channel TRPV1 regulates the activation and proinflammatory properties of CD4⁺ T cells. Nat Immunol. 2014 Nov; 15(11):1055-1063.
Bertin S, Aoki-Nonaka Y, de Jong PR, Nohara LL, Xu H, Stanwood SR, Srikanth S, Lee J, To K, Abramson L, Yu T, Han T, Touma R, Li X, González-Navajas JM, Herdman S, Corr M, Fu G, Dong H, Gwack Y, Franco A, Jefferies WA, Raz E. PMID: 25282159.
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TRPM8 on mucosal sensory nerves regulates colitogenic responses by innate immune cells via CGRP. Mucosal Immunol. 2015 May; 8(3):491-504.
de Jong PR, Takahashi N, Peiris M, Bertin S, Lee J, Gareau MG, Paniagua A, Harris AR, Herdman DS, Corr M, Blackshaw LA, Raz E. PMID: 25269705.
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27 Fields:
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Ion channel TRPV1-dependent activation of PTP1B suppresses EGFR-associated intestinal tumorigenesis. J Clin Invest. 2014 Sep; 124(9):3793-806.
de Jong PR, Takahashi N, Harris AR, Lee J, Bertin S, Jeffries J, Jung M, Duong J, Triano AI, Lee J, Niv Y, Herdman DS, Taniguchi K, Kim CW, Dong H, Eckmann L, Stanford SM, Bottini N, Corr M, Raz E. PMID: 25083990.
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28 Fields:
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Novel immune function for the TRPV1 channel in T lymphocytes. Channels (Austin). 2014; 8(6):479-80.
Bertin S, de Jong PR, Jefferies WA, Raz E. PMID: 25530461.
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6 Fields:
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Divergent requirement for Gαs and cAMP in the differentiation and inflammatory profile of distinct mouse Th subsets. J Clin Invest. 2012 Mar; 122(3):963-73.
Li X, Murray F, Koide N, Goldstone J, Dann SM, Chen J, Bertin S, Fu G, Weinstein LS, Chen M, Corr M, Eckmann L, Insel PA, Raz E. PMID: 22326954.
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