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Shiyin Yao

SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A Novel Synthetic Dual Agonistic Liposomal TLR4/7 Adjuvant Promotes Broad Immune Responses in an Influenza Vaccine With Minimal Reactogenicity. Front Immunol. 2020; 11:1207. Sato-Kaneko F, Yao S, Lao FS, Shpigelman J, Messer K, Pu M, Shukla NM, Cottam HB, Chan M, Chu PJ, Burkhart D, Schoener R, Matsutani T, Carson DA, Corr M, Hayashi T. PMID: 32636840.
      View in: PubMed   Mentions:    Fields:    
    2. Structure-Activity Relationship Studies To Identify Affinity Probes in Bis-aryl Sulfonamides That Prolong Immune Stimuli. J Med Chem. 2019 11 14; 62(21):9521-9540. Chan M, Lao FS, Chu PJ, Shpigelman J, Yao S, Nan J, Sato-Kaneko F, Li V, Hayashi T, Corr M, Carson DA, Cottam HB, Shukla NM. PMID: 31603681.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. Discovery of a Novel Microtubule Targeting Agent as an Adjuvant for Cancer Immunotherapy. Biomed Res Int. 2018; 2018:8091283. Sato-Kaneko F, Wang X, Yao S, Hosoya T, Lao FS, Messer K, Pu M, Shukla NM, Cottam HB, Chan M, Carson DA, Corr M, Hayashi T. PMID: 30406141.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    4. Induction of oligoclonal CD8 T cell responses against pulmonary metastatic cancer by a phospholipid-conjugated TLR7 agonist. Proc Natl Acad Sci U S A. 2018 07 17; 115(29):E6836-E6844. Hosoya T, Sato-Kaneko F, Ahmadi A, Yao S, Lao F, Kitaura K, Matsutani T, Carson DA, Hayashi T. PMID: 29967183.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    5. Identification of Compounds That Prolong Type I Interferon Signaling as Potential Vaccine Adjuvants. SLAS Discov. 2018 10; 23(9):960-973. Shukla NM, Arimoto KI, Yao S, Fan JB, Zhang Y, Sato-Kaneko F, Lao FS, Hosoya T, Messer K, Pu M, Cottam HB, Carson DA, Hayashi T, Zhang DE, Corr M. PMID: 29751735.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    6. Structure-Activity Relationship Studies of Pyrimido[5,4-b]indoles as Selective Toll-Like Receptor 4 Ligands. J Med Chem. 2017 11 22; 60(22):9142-9161. Chan M, Kakitsubata Y, Hayashi T, Ahmadi A, Yao S, Shukla NM, Oyama SY, Baba A, Nguyen B, Corr M, Suda Y, Carson DA, Cottam HB, Wakao M. PMID: 29049886.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    7. Combination immunotherapy with TLR agonists and checkpoint inhibitors suppresses head and neck cancer. JCI Insight. 2017 09 21; 2(18). Sato-Kaneko F, Yao S, Ahmadi A, Zhang SS, Hosoya T, Kaneda MM, Varner JA, Pu M, Messer KS, Guiducci C, Coffman RL, Kitaura K, Matsutani T, Suzuki R, Carson DA, Hayashi T, Cohen EE. PMID: 28931759.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    8. Identification of Biologically Active Pyrimido[5,4-b]indoles That Prolong NF-κB Activation without Intrinsic Activity. ACS Comb Sci. 2017 08 14; 19(8):533-543. Chan M, Ahmadi A, Yao S, Sato-Kaneko F, Messer K, Pu M, Nguyen B, Hayashi T, Corr M, Carson DA, Cottam HB, Shukla NM. PMID: 28657707.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    9. Enhancement of the Immunostimulatory Activity of a TLR7 Ligand by Conjugation to Polysaccharides. Bioconjug Chem. 2015 Aug 19; 26(8):1713-23. Shinchi H, Crain B, Yao S, Chan M, Zhang SS, Ahmadiiveli A, Suda Y, Hayashi T, Cottam HB, Carson DA. PMID: 26193334.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    10. Induction of Tolerogenic Dendritic Cells by a PEGylated TLR7 Ligand for Treatment of Type 1 Diabetes. PLoS One. 2015; 10(6):e0129867. Hayashi T, Yao S, Crain B, Promessi VJ, Shyu L, Sheng C, Kang M, Cottam HB, Carson DA, Corr M. PMID: 26076454.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    11. Discovery of substituted 4-aminoquinazolines as selective Toll-like receptor 4 ligands. Bioorg Med Chem Lett. 2014 Nov 01; 24(21):4931-8. Nour A, Hayashi T, Chan M, Yao S, Tawatao RI, Crain B, Tsigelny IF, Kouznetsova VL, Ahmadiiveli A, Messer K, Pu M, Corr M, Carson DA, Cottam HB. PMID: 25288184.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    12. Novel synthetic toll-like receptor 4/MD2 ligands attenuate sterile inflammation. J Pharmacol Exp Ther. 2014 Aug; 350(2):330-40. Hayashi T, Crain B, Yao S, Caneda CD, Cottam HB, Chan M, Corr M, Carson DA. PMID: 24893985.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    13. The WNT receptor FZD7 is required for maintenance of the pluripotent state in human embryonic stem cells. Proc Natl Acad Sci U S A. 2014 Jan 28; 111(4):1409-14. Fernandez A, Huggins IJ, Perna L, Brafman D, Lu D, Yao S, Gaasterland T, Carson DA, Willert K. PMID: 24474766.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    14. Innate immune protection against infectious diseases by pulmonary administration of a phospholipid-conjugated TLR7 ligand. J Innate Immun. 2014; 6(3):315-24. Wu CC, Crain B, Yao S, Sabet M, Lao FS, Tawatao RI, Chan M, Smee DF, Julander JG, Cottam HB, Guiney DG, Corr M, Carson DA, Hayashi T. PMID: 24192551.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    15. Identification of substituted pyrimido[5,4-b]indoles as selective Toll-like receptor 4 ligands. J Med Chem. 2013 Jun 13; 56(11):4206-23. Chan M, Hayashi T, Mathewson RD, Nour A, Hayashi Y, Yao S, Tawatao RI, Crain B, Tsigelny IF, Kouznetsova VL, Messer K, Pu M, Corr M, Carson DA, Cottam HB. PMID: 23656327.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    16. Treatment of autoimmune inflammation by a TLR7 ligand regulating the innate immune system. PLoS One. 2012; 7(9):e45860. Hayashi T, Yao S, Crain B, Chan M, Tawatao RI, Gray C, Vuong L, Lao F, Cottam HB, Carson DA, Corr M. PMID: 23029281.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    17. Mast cell-mediated inhibition of abdominal neutrophil inflammation by a PEGylated TLR7 ligand. Mediators Inflamm. 2012; 2012:262394. Hayashi T, Yao S, Crain B, Chan M, Cottam HB, Lao F, Carson DA, Corr M. PMID: 22619481.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    18. Synthesis and characterization of PEGylated toll like receptor 7 ligands. Bioconjug Chem. 2011 Mar 16; 22(3):445-54. Chan M, Hayashi T, Mathewson RD, Yao S, Gray C, Tawatao RI, Kalenian K, Zhang Y, Hayashi Y, Lao FS, Cottam HB, Carson DA. PMID: 21338093.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    19. Additive melanoma suppression with intralesional phospholipid-conjugated TLR7 agonists and systemic IL-2. Melanoma Res. 2011 Feb; 21(1):66-75. Hayashi T, Chan M, Norton JT, Wu CC, Yao S, Cottam HB, Tawatao RI, Corr M, Carson DA, Daniels GA. PMID: 21030882.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    20. Nrf2 responses and the therapeutic selectivity of electrophilic compounds in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A. 2010 Apr 20; 107(16):7479-84. Wu RP, Hayashi T, Cottam HB, Jin G, Yao S, Wu CC, Rosenbach MD, Corr M, Schwab RB, Carson DA. PMID: 20368435.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    21. Ethacrynic acid exhibits selective toxicity to chronic lymphocytic leukemia cells by inhibition of the Wnt/beta-catenin pathway. PLoS One. 2009 Dec 14; 4(12):e8294. Lu D, Liu JX, Endo T, Zhou H, Yao S, Willert K, Schmidt-Wolf IG, Kipps TJ, Carson DA. PMID: 20011538.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    22. Amide derivatives of ethacrynic acid: synthesis and evaluation as antagonists of Wnt/beta-catenin signaling and CLL cell survival. Bioorg Med Chem Lett. 2009 Feb 01; 19(3):606-9. Jin G, Lu D, Yao S, Wu CC, Liu JX, Carson DA, Cottam HB. PMID: 19121941.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    23. Localization of the naturally occurring plasmid ColE1 at the cell pole. J Bacteriol. 2007 Mar; 189(5):1946-53. Yao S, Helinski DR, Toukdarian A. PMID: 17158664.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    24. Inhibition of protein and RNA synthesis in Escherichia coli results in declustering of plasmid RK2. Plasmid. 2006 Sep; 56(2):124-32. Yao S, Toukdarian A, Helinski DR. PMID: 16774785.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    25. Functional analysis of two putative chromosomal replication origins from Pseudomonas aeruginosa. Plasmid. 2006 May; 55(3):194-200. Jiang Y, Yao S, Helinski D, Toukdarian A. PMID: 16376988.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    26. Gyrase inhibitors and thymine starvation disrupt the normal pattern of plasmid RK2 localization in Escherichia coli. J Bacteriol. 2005 May; 187(10):3538-47. Johnson EP, Yao S, Helinski DR. PMID: 15866942.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
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