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Ananda Goldrath

TitleResearcher
InstitutionUniversity of California San Diego
DepartmentMolecular Biology
Address9500 Gilman Drive #0377
La Jolla CA 92093
Phone858-534-5839
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    Collapse Research 
    Collapse Research Activities and Funding
    Molecular Determinants of Tissue-resident Memory T cell Fate in Acute and Chronic Infection
    NIH/NIAID P01AI132122Jul 17, 2018 - Jun 30, 2023
    Role: Principal Investigator
    Mutagenic chain reaction-facilitated immunotherapy
    NIH/NIAID R01AI131081Sep 9, 2016 - Aug 31, 2021
    Role: Principal Investigator
    Genetic screens for key transcriptional regulators of antiviral T cell immunity
    NIH U19AI109976Mar 1, 2014 - Feb 28, 2019
    Role: Co-Investigator
    Metabolic Regulation of T cell Immunity
    NIH/NIAID R01AI096852Aug 1, 2012 - Jul 31, 2016
    Role: Principal Investigator
    Regulation of T cell immunity to viral infection
    NIH/NIAID R01AI072117Dec 5, 2006 - Jun 30, 2023
    Role: Principal Investigator
    T cell maintenance: molecular mediators of T cell differentiation and survival
    NIH/NIAID R01AI067545Dec 1, 2005 - Jun 30, 2022
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Smith-Raska MR, Arenzana TL, D'Cruz LM, Khodadadi-Jamayran A, Tsirigos A, Goldrath A, Reizis B. The Transcription Factor Zfx Regulates Peripheral T Cell Self-Renewal and Proliferation. Front Immunol. 2018; 9:1482. PMID: 30022979.
      View in: PubMed
    2. Wang D, Diao H, Getzler AJ, Rogal W, Frederick MA, Milner J, Yu B, Crotty S, Goldrath A, Pipkin ME. The Transcription Factor Runx3 Establishes Chromatin Accessibility of cis-Regulatory Landscapes that Drive Memory Cytotoxic T Lymphocyte Formation. Immunity. 2018 Apr 17; 48(4):659-674.e6. PMID: 29669249.
      View in: PubMed
    3. Milner JJ, Goldrath A. Transcriptional programming of tissue-resident memory CD8+ T cells. Curr Opin Immunol. 2018 Apr; 51:162-169. PMID: 29621697.
      View in: PubMed
    4. Omilusik KD, Nadjsombati MS, Shaw LA, Yu B, Milner JJ, Goldrath A. Sustained Id2 regulation of E proteins is required for terminal differentiation of effector CD8+ T cells. J Exp Med. 2018 Mar 05; 215(3):773-783. PMID: 29440362.
      View in: PubMed
    5. Milner JJ, Toma C, Yu B, Zhang K, Omilusik K, Phan AT, Wang D, Getzler AJ, Nguyen T, Crotty S, Wang W, Pipkin ME, Goldrath A. Erratum: Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours. Nature. 2018 Feb 15; 554(7692):392. PMID: 29320476.
      View in: PubMed
    6. Delpoux A, Michelini RH, Verma S, Lai CY, Omilusik KD, Utzschneider DT, Redwood AJ, Goldrath A, Benedict CA, Hedrick SM. Continuous activity of Foxo1 is required to prevent anergy and maintain the memory state of CD8+ T cells. J Exp Med. 2018 Feb 05; 215(2):575-594. PMID: 29282254.
      View in: PubMed
    7. Omilusik KD, Goldrath A. The origins of memory T cells. Nature. 2017 12 21; 552(7685):337-339. PMID: 29293221.
      View in: PubMed
    8. Milner JJ, Toma C, Yu B, Zhang K, Omilusik K, Phan AT, Wang D, Getzler AJ, Nguyen T, Crotty S, Wang W, Pipkin ME, Goldrath A. Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours. Nature. 2017 12 14; 552(7684):253-257. PMID: 29211713.
      View in: PubMed
    9. Palazon A, Tyrakis PA, Macias D, Veliça P, Rundqvist H, Fitzpatrick S, Vojnovic N, Phan AT, Loman N, Hedenfalk I, Hatschek T, Lövrot J, Foukakis T, Goldrath A, Bergh J, Johnson RS. An HIF-1a/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression. Cancer Cell. 2017 Nov 13; 32(5):669-683.e5. PMID: 29136509.
      View in: PubMed
    10. Widjaja CE, Olvera JG, Metz PJ, Phan AT, Savas JN, de Bruin G, Leestemaker Y, Berkers CR, de Jong A, Florea BI, Fisch K, Lopez J, Kim SH, Garcia DA, Searles S, Bui JD, Chang AN, Yates JR, Goldrath A, Overkleeft HS, Ovaa H, Chang JT. Proteasome activity regulates CD8+ T lymphocyte metabolism and fate specification. J Clin Invest. 2017 Oct 02; 127(10):3609-3623. PMID: 28846070.
      View in: PubMed
    11. Yu B, Zhang K, Milner JJ, Toma C, Chen R, Scott-Browne JP, Pereira RM, Crotty S, Chang JT, Pipkin ME, Wang W, Goldrath A. Erratum: Epigenetic landscapes reveal transcription factors that regulate CD8+ T cell differentiation. Nat Immunol. 2017 05 18; 18(6):705. PMID: 28518161.
      View in: PubMed
    12. Phan AT, Goldrath A, Glass CK. Metabolic and Epigenetic Coordination of T Cell and Macrophage Immunity. Immunity. 2017 05 16; 46(5):714-729. PMID: 28514673.
      View in: PubMed
    13. Yu B, Zhang K, Milner JJ, Toma C, Chen R, Scott-Browne JP, Pereira RM, Crotty S, Chang JT, Pipkin ME, Wang W, Goldrath A. Epigenetic landscapes reveal transcription factors that regulate CD8+ T cell differentiation. Nat Immunol. 2017 05; 18(5):573-582. PMID: 28288100.
      View in: PubMed
    14. Kakaradov B, Arsenio J, Widjaja CE, He Z, Aigner S, Metz PJ, Yu B, Wehrens EJ, Lopez J, Kim SH, Zuniga EI, Goldrath A, Chang JT, Yeo GW. Early transcriptional and epigenetic regulation of CD8+ T cell differentiation revealed by single-cell RNA sequencing. Nat Immunol. 2017 04; 18(4):422-432. PMID: 28218746.
      View in: PubMed
    15. Phan AT, Doedens AL, Palazon A, Tyrakis PA, Cheung KP, Johnson RS, Goldrath A. Constitutive Glycolytic Metabolism Supports CD8+ T Cell Effector Memory Differentiation during Viral Infection. Immunity. 2016 11 15; 45(5):1024-1037. PMID: 27836431.
      View in: PubMed
    16. Tyrakis PA, Palazon A, Macias D, Lee KL, Phan AT, Veliça P, You J, Chia GS, Sim J, Doedens A, Abelanet A, Evans CE, Griffiths JR, Poellinger L, Goldrath A, Johnson RS. S-2-hydroxyglutarate regulates CD8+ T-lymphocyte fate. Nature. 2016 12 08; 540(7632):236-241. PMID: 27798602.
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    17. Clever D, Roychoudhuri R, Constantinides MG, Askenase MH, Sukumar M, Klebanoff CA, Eil RL, Hickman HD, Yu Z, Pan JH, Palmer DC, Phan AT, Goulding J, Gattinoni L, Goldrath A, Belkaid Y, Restifo NP. Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche. Cell. 2016 Aug 25; 166(5):1117-1131.e14. PMID: 27565342.
      View in: PubMed
    18. Doedens AL, Rubinstein MP, Gross ET, Best JA, Craig DH, Baker MK, Cole DJ, Bui JD, Goldrath A. Molecular Programming of Tumor-Infiltrating CD8+ T Cells and IL15 Resistance. Cancer Immunol Res. 2016 09 02; 4(9):799-811. PMID: 27485135.
      View in: PubMed
    19. Shaw LA, Bélanger S, Omilusik KD, Cho S, Scott-Browne JP, Nance JP, Goulding J, Lasorella A, Lu LF, Crotty S, Goldrath A. Id2 reinforces TH1 differentiation and inhibits E2A to repress TFH differentiation. Nat Immunol. 2016 07; 17(7):834-43. PMID: 27213691; PMCID: PMC4915968 [Available on 11/23/16].
    20. Stradner MH, Cheung KP, Lasorella A, Goldrath A, D'Cruz LM. Id2 regulates hyporesponsive invariant natural killer T cells. Immunol Cell Biol. 2016 08; 94(7):640-5. PMID: 26880074; PMCID: PMC4980213.
    21. Chea S, Schmutz S, Berthault C, Perchet T, Petit M, Burlen-Defranoux O, Goldrath A, Rodewald HR, Cumano A, Golub R. Single-Cell Gene Expression Analyses Reveal Heterogeneous Responsiveness of Fetal Innate Lymphoid Progenitors to Notch Signaling. Cell Rep. 2016 Feb 16; 14(6):1500-1516. PMID: 26832410.
      View in: PubMed
    22. Almaden JV, Liu YC, Yang E, Otero DC, Birnbaum H, Davis-Turak J, Asagiri M, David M, Goldrath A, Hoffmann A. B-cell survival and development controlled by the coordination of NF-?B family members RelB and cRel. Blood. 2016 Mar 10; 127(10):1276-86. PMID: 26773039; PMCID: PMC4786837 [Available on 03/10/17].
    23. Su EW, Moore CJ, Suriano S, Johnson CB, Songalia N, Patterson A, Neitzke DJ, Andrijauskaite K, Garrett-Mayer E, Mehrotra S, Paulos CM, Doedens AL, Goldrath A, Li Z, Cole DJ, Rubinstein MP. IL-2Ra mediates temporal regulation of IL-2 signaling and enhances immunotherapy. Sci Transl Med. 2015 Oct 28; 7(311):311ra170. PMID: 26511507; PMCID: PMC4805116 [Available on 10/28/16].
    24. Omilusik KD, Best JA, Yu B, Goossens S, Weidemann A, Nguyen JV, Seuntjens E, Stryjewska A, Zweier C, Roychoudhuri R, Gattinoni L, Bird LM, Higashi Y, Kondoh H, Huylebroeck D, Haigh J, Goldrath A. Transcriptional repressor ZEB2 promotes terminal differentiation of CD8+ effector and memory T cell populations during infection. J Exp Med. 2015 Nov 16; 212(12):2027-39. PMID: 26503445.
      View in: PubMed
    25. Phan AT, Goldrath A. Hypoxia-inducible factors regulate T cell metabolism and function. Mol Immunol. 2015 Dec; 68(2 Pt C):527-35. PMID: 26298577.
      View in: PubMed
    26. Stone EL, Pepper M, Katayama CD, Kerdiles YM, Lai CY, Emslie E, Lin YC, Yang E, Goldrath A, Li MO, Cantrell DA, Hedrick SM. ICOS coreceptor signaling inactivates the transcription factor FOXO1 to promote Tfh cell differentiation. Immunity. 2015 Feb 17; 42(2):239-251. PMID: 25692700.
      View in: PubMed
    27. Goossens S, Radaelli E, Blanchet O, Durinck K, Van der Meulen J, Peirs S, Taghon T, Tremblay CS, Costa M, Farhang Ghahremani M, De Medts J, Bartunkova S, Haigh K, Schwab C, Farla N, Pieters T, Matthijssens F, Van Roy N, Best JA, Deswarte K, Bogaert P, Carmichael C, Rickard A, Suryani S, Bracken LS, Alserihi R, Canté-Barrett K, Haenebalcke L, Clappier E, Rondou P, Slowicka K, Huylebroeck D, Goldrath A, Janzen V, McCormack MP, Lock RB, Curtis DJ, Harrison C, Berx G, Speleman F, Meijerink JP, Soulier J, Van Vlierberghe P, Haigh JJ. ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling. Nat Commun. 2015 Jan 07; 6:5794. PMID: 25565005; PMCID: PMC4354161.
    28. Chang JT, Wherry EJ, Goldrath A. Molecular regulation of effector and memory T cell differentiation. Nat Immunol. 2014 Dec; 15(12):1104-15. PMID: 25396352; PMCID: PMC4386685.
    29. Fulton RB, Hamilton SE, Xing Y, Best JA, Goldrath A, Hogquist KA, Jameson SC. The TCR's sensitivity to self peptide-MHC dictates the ability of naive CD8(+) T cells to respond to foreign antigens. Nat Immunol. 2015 Jan; 16(1):107-17. PMID: 25419629; PMCID: PMC4270846.
    30. Palazon A, Goldrath A, Nizet V, Johnson RS. HIF transcription factors, inflammation, and immunity. Immunity. 2014 Oct 16; 41(4):518-28. PMID: 25367569; PMCID: PMC4346319.
    31. D'Cruz LM, Stradner MH, Yang CY, Goldrath A. E and Id proteins influence invariant NKT cell sublineage differentiation and proliferation. J Immunol. 2014 Mar 01; 192(5):2227-36. PMID: 24470501; PMCID: PMC3943952.
    32. Rong Z, Wang M, Hu Z, Stradner M, Zhu S, Kong H, Yi H, Goldrath A, Yang YG, Xu Y, Fu X. An effective approach to prevent immune rejection of human ESC-derived allografts. Cell Stem Cell. 2014 Jan 02; 14(1):121-30. PMID: 24388175; PMCID: PMC4023958.
    33. Cowburn AS, Takeda N, Boutin AT, Kim JW, Sterling JC, Nakasaki M, Southwood M, Goldrath A, Jamora C, Nizet V, Chilvers ER, Johnson RS. HIF isoforms in the skin differentially regulate systemic arterial pressure. Proc Natl Acad Sci U S A. 2013 Oct 22; 110(43):17570-5. PMID: 24101470.
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    34. Rubinstein MP, Salem ML, Doedens AL, Moore CJ, Chiuzan C, Rivell GL, Cole DJ, Goldrath A. G-CSF/anti-G-CSF antibody complexes drive the potent recovery and expansion of CD11b+Gr-1+ myeloid cells without compromising CD8+ T cell immune responses. J Hematol Oncol. 2013 Oct 01; 6:75. PMID: 24279871; PMCID: PMC3850648.
    35. Omilusik KD, Shaw LA, Goldrath A. Remembering one's ID/E-ntity: E/ID protein regulation of T cell memory. Curr Opin Immunol. 2013 Oct; 25(5):660-6. PMID: 24094885; PMCID: PMC3839785.
    36. Doedens AL, Phan AT, Stradner MH, Fujimoto JK, Nguyen JV, Yang E, Johnson RS, Goldrath A. Hypoxia-inducible factors enhance the effector responses of CD8(+) T cells to persistent antigen. Nat Immunol. 2013 Nov; 14(11):1173-82. PMID: 24076634.
      View in: PubMed
    37. Saenz SA, Siracusa MC, Monticelli LA, Ziegler CG, Kim BS, Brestoff JR, Peterson LW, Wherry EJ, Goldrath A, Bhandoola A, Artis D. IL-25 simultaneously elicits distinct populations of innate lymphoid cells and multipotent progenitor type 2 (MPPtype2) cells. J Exp Med. 2013 Aug 26; 210(9):1823-37. PMID: 23960191; PMCID: PMC3754870.
    38. Hess Michelini R, Doedens AL, Goldrath A, Hedrick SM. Differentiation of CD8 memory T cells depends on Foxo1. J Exp Med. 2013 Jun 03; 210(6):1189-200. PMID: 23712431; PMCID: PMC3674697.
    39. Mingueneau M, Kreslavsky T, Gray D, Heng T, Cruse R, Ericson J, Bendall S, Spitzer MH, Nolan GP, Kobayashi K, von Boehmer H, Mathis D, Benoist C. The transcriptional landscape of aß T cell differentiation. Nat Immunol. 2013 Jun; 14(6):619-32. PMID: 23644507; PMCID: PMC3660436.
    40. Jojic V, Shay T, Sylvia K, Zuk O, Sun X, Kang J, Regev A, Koller D. Identification of transcriptional regulators in the mouse immune system. Nat Immunol. 2013 Jun; 14(6):633-43. PMID: 23624555; PMCID: PMC3690947.
    41. Best JA, Blair DA, Knell J, Yang E, Mayya V, Doedens A, Dustin ML, Goldrath A. Transcriptional insights into the CD8(+) T cell response to infection and memory T cell formation. Nat Immunol. 2013 Apr; 14(4):404-12. PMID: 23396170; PMCID: PMC3689652.
    42. Knell J, Best JA, Lind NA, Yang E, D'Cruz LM, Goldrath A. Id2 influences differentiation of killer cell lectin-like receptor G1(hi) short-lived CD8+ effector T cells. J Immunol. 2013 Feb 15; 190(4):1501-9. PMID: 23325888; PMCID: PMC3563862.
    43. Li HS, Yang CY, Nallaparaju KC, Zhang H, Liu YJ, Goldrath A, Watowich SS. The signal transducers STAT5 and STAT3 control expression of Id2 and E2-2 during dendritic cell development. Blood. 2012 Nov 22; 120(22):4363-73. PMID: 23033267; PMCID: PMC3507145.
    44. Hedrick SM, Hess Michelini R, Doedens AL, Goldrath A, Stone EL. FOXO transcription factors throughout T cell biology. Nat Rev Immunol. 2012 Sep; 12(9):649-61. PMID: 22918467; PMCID: PMC3875397.
    45. Bezman NA, Kim CC, Sun JC, Min-Oo G, Hendricks DW, Kamimura Y, Best JA, Goldrath A, Lanier LL. Molecular definition of the identity and activation of natural killer cells. Nat Immunol. 2012 Oct; 13(10):1000-9. PMID: 22902830; PMCID: PMC3572860.
    46. D'Cruz LM, Lind KC, Wu BB, Fujimoto JK, Goldrath A. Loss of E protein transcription factors E2A and HEB delays memory-precursor formation during the CD8+ T-cell immune response. Eur J Immunol. 2012 Aug; 42(8):2031-41. PMID: 22585759; PMCID: PMC3702188.
    47. Yang CY, Best JA, Knell J, Yang E, Sheridan AD, Jesionek AK, Li HS, Rivera RR, Lind KC, D'Cruz LM, Watowich SS, Murre C, Goldrath A. The transcriptional regulators Id2 and Id3 control the formation of distinct memory CD8+ T cell subsets. Nat Immunol. 2011 Nov 06; 12(12):1221-9. PMID: 22057289; PMCID: PMC3872000.
    48. Monticelli LA, Sonnenberg GF, Abt MC, Alenghat T, Ziegler CG, Doering TA, Angelosanto JM, Laidlaw BJ, Yang CY, Sathaliyawala T, Kubota M, Turner D, Diamond JM, Goldrath A, Farber DL, Collman RG, Wherry EJ, Artis D. Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus. Nat Immunol. 2011 Nov; 12(11):1045-54. PMID: 21946417.
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    49. Elpek KG, Rubinstein MP, Bellemare-Pelletier A, Goldrath A, Turley SJ. Mature natural killer cells with phenotypic and functional alterations accumulate upon sustained stimulation with IL-15/IL-15Ralpha complexes. Proc Natl Acad Sci U S A. 2010 Dec 14; 107(50):21647-52. PMID: 21098276; PMCID: PMC3003106.
    50. Doedens AL, Stockmann C, Rubinstein MP, Liao D, Zhang N, DeNardo DG, Coussens LM, Karin M, Goldrath A, Johnson RS. Macrophage expression of hypoxia-inducible factor-1 alpha suppresses T-cell function and promotes tumor progression. Cancer Res. 2010 Oct 01; 70(19):7465-75. PMID: 20841473; PMCID: PMC2948598.
    51. D'Cruz LM, Yang CY, Goldrath A. Transcriptional regulation of NKT cell development and homeostasis. Curr Opin Immunol. 2010 Apr; 22(2):199-205. PMID: 20171073; PMCID: PMC2854242.
    52. D'Cruz LM, Knell J, Fujimoto JK, Goldrath A. An essential role for the transcription factor HEB in thymocyte survival, Tcra rearrangement and the development of natural killer T cells. Nat Immunol. 2010 Mar; 11(3):240-9. PMID: 20154672; PMCID: PMC2993240.
    53. Monticelli LA, Yang Y, Knell J, D'Cruz LM, Cannarile MA, Engel I, Kronenberg M, Goldrath A. Transcriptional regulator Id2 controls survival of hepatic NKT cells. Proc Natl Acad Sci U S A. 2009 Nov 17; 106(46):19461-6. PMID: 19884494; PMCID: PMC2780802.
    54. Cheung KP, Yang E, Goldrath A. Memory-like CD8+ T cells generated during homeostatic proliferation defer to antigen-experienced memory cells. J Immunol. 2009 Sep 01; 183(5):3364-72. PMID: 19675163; PMCID: PMC2866069.
    55. D'Cruz LM, Rubinstein MP, Goldrath A. Surviving the crash: transitioning from effector to memory CD8+ T cell. Semin Immunol. 2009 Apr; 21(2):92-8. PMID: 19269192; PMCID: PMC2671236.
    56. Rubinstein MP, Lind NA, Purton JF, Filippou P, Best JA, McGhee PA, Surh CD, Goldrath A. IL-7 and IL-15 differentially regulate CD8+ T-cell subsets during contraction of the immune response. Blood. 2008 Nov 01; 112(9):3704-12. PMID: 18689546; PMCID: PMC2572798.
    57. Park KW, Waki H, Villanueva CJ, Monticelli LA, Hong C, Kang S, MacDougald OA, Goldrath A, Tontonoz P. Inhibitor of DNA binding 2 is a small molecule-inducible modulator of peroxisome proliferator-activated receptor-gamma expression and adipocyte differentiation. Mol Endocrinol. 2008 Sep; 22(9):2038-48. PMID: 18562627; PMCID: PMC2631374.
    58. Epardaud M, Elpek KG, Rubinstein MP, Yonekura AR, Bellemare-Pelletier A, Bronson R, Hamerman JA, Goldrath A, Turley SJ. Interleukin-15/interleukin-15R alpha complexes promote destruction of established tumors by reviving tumor-resident CD8+ T cells. Cancer Res. 2008 Apr 15; 68(8):2972-83. PMID: 18413767.
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    59. Cannarile MA, Lind NA, Rivera R, Sheridan AD, Camfield KA, Wu BB, Cheung KP, Ding Z, Goldrath A. Transcriptional regulator Id2 mediates CD8+ T cell immunity. Nat Immunol. 2006 Dec; 7(12):1317-25. PMID: 17086188.
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    60. Hyatt G, Melamed R, Park R, Seguritan R, Laplace C, Poirot L, Zucchelli S, Obst R, Matos M, Venanzi E, Goldrath A, Nguyen L, Luckey J, Yamagata T, Herman A, Jacobs J, Mathis D, Benoist C. Gene expression microarrays: glimpses of the immunological genome. Nat Immunol. 2006 Jul; 7(7):686-91. PMID: 16785882.
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    61. Ikawa T, Kawamoto H, Goldrath A, Murre C. E proteins and Notch signaling cooperate to promote T cell lineage specification and commitment. J Exp Med. 2006 May 15; 203(5):1329-42. PMID: 16682500; PMCID: PMC2121213.
    62. Luckey CJ, Bhattacharya D, Goldrath A, Weissman IL, Benoist C, Mathis D. Memory T and memory B cells share a transcriptional program of self-renewal with long-term hematopoietic stem cells. Proc Natl Acad Sci U S A. 2006 Feb 28; 103(9):3304-9. PMID: 16492737; PMCID: PMC1413911.
    63. Intlekofer AM, Takemoto N, Wherry EJ, Longworth SA, Northrup JT, Palanivel VR, Mullen AC, Gasink CR, Kaech SM, Miller JD, Gapin L, Ryan K, Russ AP, Lindsten T, Orange JS, Goldrath A, Ahmed R, Reiner SL. Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin. Nat Immunol. 2005 Dec; 6(12):1236-44. PMID: 16273099.
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    64. Goldrath A, Hedrick SM. Central tolerance matters. Immunity. 2005 Aug; 23(2):113-4. PMID: 16111630.
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    65. Goldrath A, Luckey CJ, Park R, Benoist C, Mathis D. The molecular program induced in T cells undergoing homeostatic proliferation. Proc Natl Acad Sci U S A. 2004 Nov 30; 101(48):16885-90. PMID: 15548615; PMCID: PMC534746.
    66. Goldrath A, Sivakumar PV, Glaccum M, Kennedy MK, Bevan MJ, Benoist C, Mathis D, Butz EA. Cytokine requirements for acute and Basal homeostatic proliferation of naive and memory CD8+ T cells. J Exp Med. 2002 Jun 17; 195(12):1515-22. PMID: 12070279; PMCID: PMC2193554.
    67. Goldrath A. Maintaining the status quo: T-cell homeostasis. Microbes Infect. 2002 Apr; 4(5):539-45. PMID: 11959509.
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