Ananda Goldrath

Title(s)Professor, Molecular Biology
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    Molecular Determinants of Tissue-resident Memory T cell Fate in Acute and Chronic Infection
    NIH P01AI132122Jul 17, 2018 - Jun 30, 2023
    Role: Principal Investigator
    Mutagenic chain reaction-facilitated immunotherapy
    NIH R01AI131081Sep 9, 2016 - Aug 31, 2021
    Role: Principal Investigator
    Genetic screens for key transcriptional regulators of antiviral T cell immunity
    NIH U19AI109976Mar 1, 2014 - Feb 28, 2019
    Role: Co-Investigator
    Metabolic Regulation of T cell Immunity
    NIH R01AI096852Aug 1, 2012 - Jul 31, 2017
    Role: Principal Investigator
    Regulation of T cell immunity to viral infection
    NIH R01AI072117Dec 5, 2006 - Jun 30, 2023
    Role: Principal Investigator
    T cell maintenance: molecular mediators of T cell differentiation and survival
    NIH R01AI067545Dec 1, 2005 - Jun 30, 2022
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ubiquitin Specific Protease 1 Expression and Function in T Cell Immunity. J Immunol. 2021 09 01; 207(5):1377-1387. Omilusik KD, Nadjsombati MS, Yoshida TM, Shaw LA, Goulding J, Goldrath AW. PMID: 34380645.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCellsPHPublic Health
    2. Bromodomain protein BRD4 directs and sustains CD8 T cell differentiation during infection. J Exp Med. 2021 Aug 02; 218(8). Milner JJ, Toma C, Quon S, Omilusik K, Scharping NE, Dey A, Reina-Campos M, Nguyen H, Getzler AJ, Diao H, Yu B, Delpoux A, Yoshida TM, Li D, Qi J, Vincek A, Hedrick SM, Egawa T, Zhou MM, Crotty S, Ozato K, Pipkin ME, Goldrath AW. PMID: 34037670.
      View in: PubMed   Mentions: 2     Fields:    
    3. CD8+ T cell metabolism in infection and cancer. Nat Rev Immunol. 2021 May 12. Reina-Campos M, Scharping NE, Goldrath AW. PMID: 33981085.
      View in: PubMed   Mentions:    Fields:    
    4. Hypoxia-inducible factor activity promotes antitumor effector function and tissue residency by CD8+ T cells. J Clin Invest. 2021 04 01; 131(7). Liikanen I, Lauhan C, Quon S, Omilusik K, Phan AT, Bartrolí LB, Ferry A, Goulding J, Chen J, Scott-Browne JP, Yustein JT, Scharping NE, Witherden DA, Goldrath AW. PMID: 33792560.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    5. Delineation of a molecularly distinct terminally differentiated memory CD8 T cell population. Proc Natl Acad Sci U S A. 2020 10 13; 117(41):25667-25678. Milner JJ, Nguyen H, Omilusik K, Reina-Campos M, Tsai M, Toma C, Delpoux A, Boland BS, Hedrick SM, Chang JT, Goldrath AW. PMID: 32978300.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    6. Heterogeneity and clonal relationships of adaptive immune cells in ulcerative colitis revealed by single-cell analyses. Sci Immunol. 2020 08 21; 5(50). Boland BS, He Z, Tsai MS, Olvera JG, Omilusik KD, Duong HG, Kim ES, Limary AE, Jin W, Milner JJ, Yu B, Patel SA, Louis TL, Tysl T, Kurd NS, Bortnick A, Quezada LK, Kanbar JN, Miralles A, Huylebroeck D, Valasek MA, Dulai PS, Singh S, Lu LF, Bui JD, Murre C, Sandborn WJ, Goldrath AW, Yeo GW, Chang JT. PMID: 32826341.
      View in: PubMed   Mentions: 13     Fields:    
    7. Heterogenous Populations of Tissue-Resident CD8+ T Cells Are Generated in Response to Infection and Malignancy. Immunity. 2020 05 19; 52(5):808-824.e7. Milner JJ, Toma C, He Z, Kurd NS, Nguyen QP, McDonald B, Quezada L, Widjaja CE, Witherden DA, Crowl JT, Shaw LA, Yeo GW, Chang JT, Omilusik KD, Goldrath AW. PMID: 32433949.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    8. Early precursors and molecular determinants of tissue-resident memory CD8+ T lymphocytes revealed by single-cell RNA sequencing. Sci Immunol. 2020 05 15; 5(47). Kurd NS, He Z, Louis TL, Milner JJ, Omilusik KD, Jin W, Tsai MS, Widjaja CE, Kanbar JN, Olvera JG, Tysl T, Quezada LK, Boland BS, Huang WJ, Murre C, Goldrath AW, Yeo GW, Chang JT. PMID: 32414833.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    9. Reinvigorating NIH Grant Peer Review. Immunity. 2020 01 14; 52(1):1-3. Crotty S, Blish C, Cadwell K, Chi H, Goldrath A, Green D, Kaech SM, Krummel M, Pepper M, Rothlin CV, Wherry EJ, Once-a-Year Pledge Supporters . PMID: 31940266.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Antitumour T cells stand the test of time. Nature. 2019 12; 576(7787):392-393. Reina-Campos M, Goldrath AW. PMID: 31844255.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    11. Remembering to remember: T cell memory maintenance and plasticity. Curr Opin Immunol. 2019 06; 58:89-97. Omilusik KD, Goldrath AW. PMID: 31170601.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    12. T-bet Transcription Factor Promotes Antibody-Secreting Cell Differentiation by Limiting the Inflammatory Effects of IFN-γ on B Cells. Immunity. 2019 05 21; 50(5):1172-1187.e7. Stone SL, Peel JN, Scharer CD, Risley CA, Chisolm DA, Schultz MD, Yu B, Ballesteros-Tato A, Wojciechowski W, Mousseau B, Misra RS, Hanidu A, Jiang H, Qi Z, Boss JM, Randall TD, Brodeur SR, Goldrath AW, Weinmann AS, Rosenberg AF, Lund FE. PMID: 31076359.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    13. Origins of CD4+ circulating and tissue-resident memory T-cells. Immunology. 2019 05; 157(1):3-12. Hanna RF, Ward TJ, Chow DS, Lagana SM, Moreira RK, Emond JC, Weintraub JL, Prince MR, Nguyen QP, Deng TZ, Witherden DA, Goldrath AW. PMID: 30897205; PMCID: PMC6459775.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    14. The Transcription Factor Runx3 Establishes Chromatin Accessibility of cis-Regulatory Landscapes that Drive Memory Cytotoxic T Lymphocyte Formation. Immunity. 2018 04 17; 48(4):659-674.e6. Wang D, Diao H, Getzler AJ, Rogal W, Frederick MA, Milner J, Yu B, Crotty S, Goldrath AW, Pipkin ME. PMID: 29669249.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    15. Transcriptional programming of tissue-resident memory CD8+ T cells. Curr Opin Immunol. 2018 04; 51:162-169. Milner JJ, Goldrath AW. PMID: 29621697.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    16. Sustained Id2 regulation of E proteins is required for terminal differentiation of effector CD8+ T cells. J Exp Med. 2018 03 05; 215(3):773-783. Omilusik KD, Nadjsombati MS, Shaw LA, Yu B, Milner JJ, Goldrath AW. PMID: 29440362.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    17. Erratum: Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours. Nature. 2018 02 15; 554(7692):392. Milner JJ, Toma C, Yu B, Zhang K, Omilusik K, Phan AT, Wang D, Getzler AJ, Nguyen T, Crotty S, Wang W, Pipkin ME, Goldrath AW. PMID: 29320476.
      View in: PubMed   Mentions: 2     Fields:    
    18. Continuous activity of Foxo1 is required to prevent anergy and maintain the memory state of CD8+ T cells. J Exp Med. 2018 02 05; 215(2):575-594. Delpoux A, Michelini RH, Verma S, Lai CY, Omilusik KD, Utzschneider DT, Redwood AJ, Goldrath AW, Benedict CA, Hedrick SM. PMID: 29282254.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    19. The origins of memory T cells. Nature. 2017 12 21; 552(7685):337-339. Omilusik KD, Goldrath AW. PMID: 29293221.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    20. Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours. Nature. 2017 12 14; 552(7684):253-257. Milner JJ, Toma C, Yu B, Zhang K, Omilusik K, Phan AT, Wang D, Getzler AJ, Nguyen T, Crotty S, Wang W, Pipkin ME, Goldrath AW. PMID: 29211713.
      View in: PubMed   Mentions: 143     Fields:    Translation:HumansAnimalsCells
    21. The origins of memory T cells. Nature. 2017 Dec; 552(7685):337-339. Omilusik KD, Goldrath AW. PMID: 32080617.
      View in: PubMed   Mentions: 4     Fields:    
    22. An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression. Cancer Cell. 2017 11 13; 32(5):669-683.e5. Palazon A, Tyrakis PA, Macias D, Veliça P, Rundqvist H, Fitzpatrick S, Vojnovic N, Phan AT, Loman N, Hedenfalk I, Hatschek T, Lövrot J, Foukakis T, Goldrath AW, Bergh J, Johnson RS. PMID: 29136509.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansAnimalsCells
    23. Proteasome activity regulates CD8+ T lymphocyte metabolism and fate specification. J Clin Invest. 2017 Oct 02; 127(10):3609-3623. Widjaja CE, Olvera JG, Metz PJ, Phan AT, Savas JN, de Bruin G, Leestemaker Y, Berkers CR, de Jong A, Florea BI, Fisch K, Lopez J, Kim SH, Garcia DA, Searles S, Bui JD, Chang AN, Yates JR, Goldrath AW, Overkleeft HS, Ovaa H, Chang JT. PMID: 28846070.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    24. Erratum: Epigenetic landscapes reveal transcription factors that regulate CD8+ T cell differentiation. Nat Immunol. 2017 05 18; 18(6):705. Yu B, Zhang K, Milner JJ, Toma C, Chen R, Scott-Browne JP, Pereira RM, Crotty S, Chang JT, Pipkin ME, Wang W, Goldrath AW. PMID: 28518161.
      View in: PubMed   Mentions: 6     Fields:    
    25. Metabolic and Epigenetic Coordination of T Cell and Macrophage Immunity. Immunity. 2017 05 16; 46(5):714-729. Phan AT, Goldrath AW, Glass CK. PMID: 28514673.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansAnimalsCells
    26. Epigenetic landscapes reveal transcription factors that regulate CD8+ T cell differentiation. Nat Immunol. 2017 05; 18(5):573-582. Yu B, Zhang K, Milner JJ, Toma C, Chen R, Scott-Browne JP, Pereira RM, Crotty S, Chang JT, Pipkin ME, Wang W, Goldrath AW. PMID: 28288100.
      View in: PubMed   Mentions: 61     Fields:    Translation:AnimalsCells
    27. Early transcriptional and epigenetic regulation of CD8+ T cell differentiation revealed by single-cell RNA sequencing. Nat Immunol. 2017 04; 18(4):422-432. Kakaradov B, Arsenio J, Widjaja CE, He Z, Aigner S, Metz PJ, Yu B, Wehrens EJ, Lopez J, Kim SH, Zuniga EI, Goldrath AW, Chang JT, Yeo GW. PMID: 28218746.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    28. Constitutive Glycolytic Metabolism Supports CD8+ T Cell Effector Memory Differentiation during Viral Infection. Immunity. 2016 11 15; 45(5):1024-1037. Phan AT, Doedens AL, Palazon A, Tyrakis PA, Cheung KP, Johnson RS, Goldrath AW. PMID: 27836431.
      View in: PubMed   Mentions: 65     Fields:    Translation:AnimalsCells
    29. Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche. Cell. 2016 Aug 25; 166(5):1117-1131.e14. Clever D, Roychoudhuri R, Constantinides MG, Askenase MH, Sukumar M, Klebanoff CA, Eil RL, Hickman HD, Yu Z, Pan JH, Palmer DC, Phan AT, Goulding J, Gattinoni L, Goldrath AW, Belkaid Y, Restifo NP. PMID: 27565342.
      View in: PubMed   Mentions: 83     Fields:    Translation:AnimalsCells
    30. Molecular Programming of Tumor-Infiltrating CD8+ T Cells and IL15 Resistance. Cancer Immunol Res. 2016 09 02; 4(9):799-811. Doedens AL, Rubinstein MP, Gross ET, Best JA, Craig DH, Baker MK, Cole DJ, Bui JD, Goldrath AW. PMID: 27485135.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    31. Id2 reinforces TH1 differentiation and inhibits E2A to repress TFH differentiation. Nat Immunol. 2016 07; 17(7):834-43. Shaw LA, Bélanger S, Omilusik KD, Cho S, Scott-Browne JP, Nance JP, Goulding J, Lasorella A, Lu LF, Crotty S, Goldrath AW. PMID: 27213691.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    32. Single-Cell Gene Expression Analyses Reveal Heterogeneous Responsiveness of Fetal Innate Lymphoid Progenitors to Notch Signaling. Cell Rep. 2016 Feb 16; 14(6):1500-1516. Chea S, Schmutz S, Berthault C, Perchet T, Petit M, Burlen-Defranoux O, Goldrath AW, Rodewald HR, Cumano A, Golub R. PMID: 26832410.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    33. B-cell survival and development controlled by the coordination of NF-κB family members RelB and cRel. Blood. 2016 Mar 10; 127(10):1276-86. Almaden JV, Liu YC, Yang E, Otero DC, Birnbaum H, Davis-Turak J, Asagiri M, David M, Goldrath AW, Hoffmann A. PMID: 26773039.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    34. IL-2Rα mediates temporal regulation of IL-2 signaling and enhances immunotherapy. Sci Transl Med. 2015 Oct 28; 7(311):311ra170. Su EW, Moore CJ, Suriano S, Johnson CB, Songalia N, Patterson A, Neitzke DJ, Andrijauskaite K, Garrett-Mayer E, Mehrotra S, Paulos CM, Doedens AL, Goldrath AW, Li Z, Cole DJ, Rubinstein MP. PMID: 26511507.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    35. Transcriptional repressor ZEB2 promotes terminal differentiation of CD8+ effector and memory T cell populations during infection. J Exp Med. 2015 Nov 16; 212(12):2027-39. Omilusik KD, Best JA, Yu B, Goossens S, Weidemann A, Nguyen JV, Seuntjens E, Stryjewska A, Zweier C, Roychoudhuri R, Gattinoni L, Bird LM, Higashi Y, Kondoh H, Huylebroeck D, Haigh J, Goldrath AW. PMID: 26503445.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansAnimalsCells
    36. Hypoxia-inducible factors regulate T cell metabolism and function. Mol Immunol. 2015 Dec; 68(2 Pt C):527-35. Phan AT, Goldrath AW. PMID: 26298577.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    37. ICOS coreceptor signaling inactivates the transcription factor FOXO1 to promote Tfh cell differentiation. Immunity. 2015 Feb 17; 42(2):239-251. Stone EL, Pepper M, Katayama CD, Kerdiles YM, Lai CY, Emslie E, Lin YC, Yang E, Goldrath AW, Li MO, Cantrell DA, Hedrick SM. PMID: 25692700.
      View in: PubMed   Mentions: 99     Fields:    Translation:AnimalsCells
    38. Molecular regulation of effector and memory T cell differentiation. Nat Immunol. 2014 Dec; 15(12):1104-15. Chang JT, Wherry EJ, Goldrath AW. PMID: 25396352.
      View in: PubMed   Mentions: 181     Fields:    Translation:HumansAnimalsCells
    39. The TCR's sensitivity to self peptide-MHC dictates the ability of naive CD8(+) T cells to respond to foreign antigens. Nat Immunol. 2015 Jan; 16(1):107-17. Fulton RB, Hamilton SE, Xing Y, Best JA, Goldrath AW, Hogquist KA, Jameson SC. PMID: 25419629.
      View in: PubMed   Mentions: 80     Fields:    Translation:AnimalsCells
    40. E and Id proteins influence invariant NKT cell sublineage differentiation and proliferation. J Immunol. 2014 Mar 01; 192(5):2227-36. D'Cruz LM, Stradner MH, Yang CY, Goldrath AW. PMID: 24470501.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    41. An effective approach to prevent immune rejection of human ESC-derived allografts. Cell Stem Cell. 2014 Jan 02; 14(1):121-30. Rong Z, Wang M, Hu Z, Stradner M, Zhu S, Kong H, Yi H, Goldrath A, Yang YG, Xu Y, Fu X. PMID: 24388175.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    42. Remembering one's ID/E-ntity: E/ID protein regulation of T cell memory. Curr Opin Immunol. 2013 Oct; 25(5):660-6. Omilusik KD, Shaw LA, Goldrath AW. PMID: 24094885.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    43. Hypoxia-inducible factors enhance the effector responses of CD8(+) T cells to persistent antigen. Nat Immunol. 2013 Nov; 14(11):1173-82. Doedens AL, Phan AT, Stradner MH, Fujimoto JK, Nguyen JV, Yang E, Johnson RS, Goldrath AW. PMID: 24076634.
      View in: PubMed   Mentions: 227     Fields:    Translation:HumansAnimalsCells
    44. IL-25 simultaneously elicits distinct populations of innate lymphoid cells and multipotent progenitor type 2 (MPPtype2) cells. J Exp Med. 2013 Aug 26; 210(9):1823-37. Saenz SA, Siracusa MC, Monticelli LA, Ziegler CG, Kim BS, Brestoff JR, Peterson LW, Wherry EJ, Goldrath AW, Bhandoola A, Artis D. PMID: 23960191.
      View in: PubMed   Mentions: 65     Fields:    Translation:AnimalsCells
    45. Differentiation of CD8 memory T cells depends on Foxo1. J Exp Med. 2013 Jun 03; 210(6):1189-200. Hess Michelini R, Doedens AL, Goldrath AW, Hedrick SM. PMID: 23712431.
      View in: PubMed   Mentions: 89     Fields:    Translation:AnimalsCells
    46. The transcriptional landscape of αβ T cell differentiation. Nat Immunol. 2013 Jun; 14(6):619-32. Mingueneau M, Kreslavsky T, Gray D, Heng T, Cruse R, Ericson J, Bendall S, Spitzer MH, Nolan GP, Kobayashi K, von Boehmer H, Mathis D, Benoist C, Immunological Genome Consortium , Best AJ, Knell J, Goldrath A, Joic V, Koller D, Shay T, Regev A, Cohen N, Brennan P, Brenner M, Kim F, Nageswara Rao T, Wagers A, Heng T, Ericson J, Rothamel K, Ortiz-Lopez A, Mathis D, Benoist C, Bezman NA, Sun JC, Min-Oo G, Kim CC, Lanier LL, Miller J, Brown B, Merad M, Gautier EL, Jakubzick C, Randolph GJ, Monach P, Blair DA, Dustin ML, Shinton SA, Hardy RR, Laidlaw D, Collins J, Gazit R, Rossi DJ, Malhotra N, Sylvia K, Kang J, Kreslavsky T, Fletcher A, Elpek K, Bellemare-Pelletier A, Malhotra D, Turley S. PMID: 23644507.
      View in: PubMed   Mentions: 111     Fields:    Translation:AnimalsCells
    47. Identification of transcriptional regulators in the mouse immune system. Nat Immunol. 2013 Jun; 14(6):633-43. Jojic V, Shay T, Sylvia K, Zuk O, Sun X, Kang J, Regev A, Koller D, Immunological Genome Project Consortium , Best AJ, Knell J, Goldrath A, Joic V, Koller D, Shay T, Regev A, Cohen N, Brennan P, Brenner M, Kim F, Rao TN, Wagers A, Heng T, Ericson J, Rothamel K, Ortiz-Lopez A, Mathis D, Benoist C, Bezman NA, Sun JC, Min-Oo G, Kim CC, Lanier LL, Miller J, Brown B, Merad M, Gautier EL, Jakubzick C, Randolph GJ, Monach P, Blair DA, Dustin ML, Shinton SA, Hardy RR, Laidlaw D, Collins J, Gazit R, Rossi DJ, Malhotra N, Sylvia K, Kang J, Kreslavsky T, Fletcher A, Elpek K, Bellemarte-Pelletier A, Malhotra D, Turley S. PMID: 23624555.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansAnimalsCells
    48. Transcriptional insights into the CD8(+) T cell response to infection and memory T cell formation. Nat Immunol. 2013 Apr; 14(4):404-12. Best JA, Blair DA, Knell J, Yang E, Mayya V, Doedens A, Dustin ML, Goldrath AW, Immunological Genome Project Consortium . PMID: 23396170.
      View in: PubMed   Mentions: 138     Fields:    Translation:AnimalsCells
    49. Id2 influences differentiation of killer cell lectin-like receptor G1(hi) short-lived CD8+ effector T cells. J Immunol. 2013 Feb 15; 190(4):1501-9. Knell J, Best JA, Lind NA, Yang E, D'Cruz LM, Goldrath AW. PMID: 23325888.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    50. The signal transducers STAT5 and STAT3 control expression of Id2 and E2-2 during dendritic cell development. Blood. 2012 Nov 22; 120(22):4363-73. Hanna RF, Ward TJ, Chow DS, Lagana SM, Moreira RK, Emond JC, Weintraub JL, Prince MR, Li HS, Yang CY, Nallaparaju KC, Zhang H, Liu YJ, Goldrath AW, Watowich SS. PMID: 23033267; PMCID: PMC3507145.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    51. FOXO transcription factors throughout T cell biology. Nat Rev Immunol. 2012 Sep; 12(9):649-61. Hedrick SM, Hess Michelini R, Doedens AL, Goldrath AW, Stone EL. PMID: 22918467.
      View in: PubMed   Mentions: 143     Fields:    Translation:HumansAnimalsCells
    52. Loss of E protein transcription factors E2A and HEB delays memory-precursor formation during the CD8+ T-cell immune response. Eur J Immunol. 2012 Aug; 42(8):2031-41. D'Cruz LM, Lind KC, Wu BB, Fujimoto JK, Goldrath AW. PMID: 22585759.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    53. The transcriptional regulators Id2 and Id3 control the formation of distinct memory CD8+ T cell subsets. Nat Immunol. 2011 Nov 06; 12(12):1221-9. Yang CY, Best JA, Knell J, Yang E, Sheridan AD, Jesionek AK, Li HS, Rivera RR, Lind KC, D'Cruz LM, Watowich SS, Murre C, Goldrath AW. PMID: 22057289.
      View in: PubMed   Mentions: 170     Fields:    Translation:AnimalsCells
    54. Macrophage expression of hypoxia-inducible factor-1 alpha suppresses T-cell function and promotes tumor progression. Cancer Res. 2010 Oct 01; 70(19):7465-75. Doedens AL, Stockmann C, Rubinstein MP, Liao D, Zhang N, DeNardo DG, Coussens LM, Karin M, Goldrath AW, Johnson RS. PMID: 20841473.
      View in: PubMed   Mentions: 245     Fields:    Translation:AnimalsCells
    55. Transcriptional regulation of NKT cell development and homeostasis. Curr Opin Immunol. 2010 Apr; 22(2):199-205. D'Cruz LM, Yang CY, Goldrath AW. PMID: 20171073.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    56. An essential role for the transcription factor HEB in thymocyte survival, Tcra rearrangement and the development of natural killer T cells. Nat Immunol. 2010 Mar; 11(3):240-9. D'Cruz LM, Knell J, Fujimoto JK, Goldrath AW. PMID: 20154672.
      View in: PubMed   Mentions: 68     Fields:    Translation:AnimalsCells
    57. Transcriptional regulator Id2 controls survival of hepatic NKT cells. Proc Natl Acad Sci U S A. 2009 Nov 17; 106(46):19461-6. Monticelli LA, Yang Y, Knell J, D'Cruz LM, Cannarile MA, Engel I, Kronenberg M, Goldrath AW. PMID: 19884494.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    58. Memory-like CD8+ T cells generated during homeostatic proliferation defer to antigen-experienced memory cells. J Immunol. 2009 Sep 01; 183(5):3364-72. Cheung KP, Yang E, Goldrath AW. PMID: 19675163.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    59. Surviving the crash: transitioning from effector to memory CD8+ T cell. Semin Immunol. 2009 Apr; 21(2):92-8. D'Cruz LM, Rubinstein MP, Goldrath AW. PMID: 19269192.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    60. IL-7 and IL-15 differentially regulate CD8+ T-cell subsets during contraction of the immune response. Blood. 2008 Nov 01; 112(9):3704-12. Rubinstein MP, Lind NA, Purton JF, Filippou P, Best JA, McGhee PA, Surh CD, Goldrath AW. PMID: 18689546.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansAnimalsCells
    61. Inhibitor of DNA binding 2 is a small molecule-inducible modulator of peroxisome proliferator-activated receptor-gamma expression and adipocyte differentiation. Mol Endocrinol. 2008 Sep; 22(9):2038-48. Park KW, Waki H, Villanueva CJ, Monticelli LA, Hong C, Kang S, MacDougald OA, Goldrath AW, Tontonoz P. PMID: 18562627.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    62. Transcriptional regulator Id2 mediates CD8+ T cell immunity. Nat Immunol. 2006 Dec; 7(12):1317-25. Cannarile MA, Lind NA, Rivera R, Sheridan AD, Camfield KA, Wu BB, Cheung KP, Ding Z, Goldrath AW. PMID: 17086188.
      View in: PubMed   Mentions: 117     Fields:    Translation:AnimalsCells
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