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Patricia Jennings

Title(s)Professor, Chemistry and Biochemistry
SchoolVc-academic Affairs
Address9500 Gilman Drive #0375
La Jolla CA 92093
Phone8/5-34--6417
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    Collapse Research 
    Collapse Research Activities and Funding
    The New Family of NEET Proteins: 2Fe-2S Protein Mediated Health and Disease
    NIH/NIGMS R01GM101467Sep 21, 2012 - Aug 31, 2016
    Role: Principal Investigator
    HTS for Modulators of MitoNEET Proteins'Function
    NIH/NIDA R03DA034597May 1, 2012 - Apr 30, 2014
    Role: Principal Investigator
    Acquisition of a 500 MHz NMR Console
    NIH/NCRR S10RR020874Apr 1, 2006 - Mar 31, 2007
    Role: Principal Investigator
    PKA & PKC Targeting Mechanisms (Program Project)
    NIH/NIDDK P01DK054441Dec 15, 1998 - Nov 30, 2001
    Role: Co-Investigator
    Investigation of the Functional/Folding Landscapes of the Il-1 Family
    NIH/NIGMS R01GM054038Aug 1, 1996 - Jul 31, 2006
    Role: Principal Investigator
    FOLDING MECHANISM OF A BETA PROTEIN
    NIH/NIGMS R29GM054038May 1, 1996 - Apr 30, 2002
    Role: Principal Investigator
    AN NMR INVESTIGATION OF PROTEIN FOLDING MECHANISMS
    NIH/NIGMS F32GM014541Dec 31, 1991
    Role: Principal Investigator
    A Synchroton Radiation Structural Biology Resource
    NIH P41RR001209Mar 1, 1980 - Feb 28, 2015
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Unraveling Allostery in a Knotted Minimal Methyltransferase by NMR Spectroscopy. J Mol Biol. 2020 Apr 17; 432(9):3018-3032. Capraro DT, Burban DJ, Jennings PA. PMID: 32135193.
      View in: PubMed   Mentions:    Fields:    
    2. The Pierced Lasso Topology Leptin has a Bolt on Dynamic Domain Composed by the Disordered Loops I and III. J Mol Biol. 2020 Apr 17; 432(9):3050-3063. Danielsson J, Noel JK, Simien JM, Duggan BM, Oliveberg M, Onuchic JN, Jennings PA, Haglund E. PMID: 32081588.
      View in: PubMed   Mentions:    Fields:    
    3. Cigarette Smoke Triggers IL-33-associated Inflammation in a Model of Late-Stage Chronic Obstructive Pulmonary Disease. Am J Respir Cell Mol Biol. 2019 11; 61(5):567-574. Lee JH, Hailey KL, Vitorino SA, Jennings PA, Bigby TD, Breen EC. PMID: 30973786.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    4. Long-term impacts of the CARE program on teachers' self-reported social and emotional competence and well-being. J Sch Psychol. 2019 Oct; 76:186-202. Jennings PA, Doyle S, Oh Y, Rasheed D, Frank JL, Brown JL. PMID: 31759466.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Redox-dependent gating of VDAC by mitoNEET. Proc Natl Acad Sci U S A. 2019 10 01; 116(40):19924-19929. Lipper CH, Stofleth JT, Bai F, Sohn YS, Roy S, Mittler R, Nechushtai R, Onuchic JN, Jennings PA. PMID: 31527235.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    6. Latent Variable Interactions With Ordered-Categorical Indicators: Comparisons of Unconstrained Product Indicator and Latent Moderated Structural Equations Approaches. Educ Psychol Meas. 2020 Apr; 80(2):262-292. Aytürk E, Cham H, Jennings PA, Brown JL. PMID: 32158022.
      View in: PubMed   Mentions:
    7. The Effect of Teacher-Child Race/Ethnicity Matching and Classroom Diversity on Children's Socioemotional and Academic Skills. Child Dev. 2020 May; 91(3):e597-e618. Rasheed DS, Brown JL, Doyle SL, Jennings PA. PMID: 31231803.
      View in: PubMed   Mentions:    Fields:    
    8. Contemplative neuroscience, self-awareness, and education. Prog Brain Res. 2019; 244:355-385. Berkovich-Ohana A, Jennings PA, Lavy S. PMID: 30732845.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. The anti-apoptotic proteins NAF-1 and iASPP interact to drive apoptosis in cancer cells. Chem Sci. 2019 Jan 21; 10(3):665-673. Iosub-Amir A, Bai F, Sohn YS, Song L, Tamir S, Marjault HB, Mayer G, Karmi O, Jennings PA, Mittler R, Onuchic JN, Friedler A, Nechushtai R. PMID: 30774867.
      View in: PubMed   Mentions:
    10. Designing bacterial signaling interactions with coevolutionary landscapes. PLoS One. 2018; 13(8):e0201734. Cheng RR, Haglund E, Tiee NS, Morcos F, Levine H, Adams JA, Jennings PA, Onuchic JN. PMID: 30125296.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    11. Uncovering the molecular mechanisms behind disease-associated leptin variants. J Biol Chem. 2018 08 17; 293(33):12919-12933. Haglund E, Nguyen L, Schafer NP, Lammert H, Jennings PA, Onuchic JN. PMID: 29950524.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. NEET Proteins: A New Link Between Iron Metabolism, Reactive Oxygen Species, and Cancer. Antioxid Redox Signal. 2019 03 10; 30(8):1083-1095. Mittler R, Darash-Yahana M, Sohn YS, Bai F, Song L, Cabantchik IZ, Jennings PA, Onuchic JN, Nechushtai R. PMID: 29463105.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    13. Phylogenetic analysis of the CDGSH iron-sulfur binding domain reveals its ancient origin. Sci Rep. 2018 03 19; 8(1):4840. Sengupta S, Nechushtai R, Jennings PA, Onuchic JN, Padilla PA, Azad RK, Mittler R. PMID: 29556009.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    14. The unique fold and lability of the [2Fe-2S] clusters of NEET proteins mediate their key functions in health and disease. J Biol Inorg Chem. 2018 06; 23(4):599-612. Karmi O, Marjault HB, Pesce L, Carloni P, Onuchic JN, Jennings PA, Mittler R, Nechushtai R. PMID: 29435647.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    15. Structure of the human monomeric NEET protein MiNT and its role in regulating iron and reactive oxygen species in cancer cells. Proc Natl Acad Sci U S A. 2018 01 09; 115(2):272-277. Lipper CH, Karmi O, Sohn YS, Darash-Yahana M, Lammert H, Song L, Liu A, Mittler R, Nechushtai R, Onuchic JN, Jennings PA. PMID: 29259115.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    16. Molecular Dynamics Simulations of the [2Fe-2S] Cluster-Binding Domain of NEET Proteins Reveal Key Molecular Determinants That Induce Their Cluster Transfer/Release. J Phys Chem B. 2017 11 30; 121(47):10648-10656. Pesce L, Calandrini V, Marjault HB, Lipper CH, Rossetti G, Mittler R, Jennings PA, Bauer A, Nechushtai R, Carloni P. PMID: 29086562.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    17. Educators' emotion regulation strategies and their physiological indicators of chronic stress over 1 year. Stress Health. 2018 Apr; 34(2):278-285. Katz DA, Harris A, Abenavoli R, Greenberg MT, Jennings PA. PMID: 28990329.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    18. Redirecting SR Protein Nuclear Trafficking through an Allosteric Platform. J Mol Biol. 2017 07 07; 429(14):2178-2191. Aubol BE, Hailey KL, Fattet L, Jennings PA, Adams JA. PMID: 28576472.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    19. Continuous subcutaneous insulin infusion (CSII) therapy at Derby Teaching Hospitals: sustained benefits in glucose control. Diabet Med. 2017 08; 34(8):1154-1157. Anyanwagu U, Olaoye H, Jennings P, Ashton-Cleary S, Sugunendran S, Hughes D, Idris I, Wilmot EG. PMID: 28430381.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    20. Interactions between mitoNEET and NAF-1 in cells. PLoS One. 2017; 12(4):e0175796. Karmi O, Holt SH, Song L, Tamir S, Luo Y, Bai F, Adenwalla A, Darash-Yahana M, Sohn YS, Jennings PA, Azad RK, Onuchic JN, Morcos F, Nechushtai R, Mittler R. PMID: 28426722.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    21. Backbone assignments for the SPOUT methyltransferase MTT Tm , a knotted protein from Thermotoga maritima. Biomol NMR Assign. 2017 Oct; 11(2):151-154. Burban DJ, Jennings PA. PMID: 28284017.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    22. Phylogenetic analysis of eukaryotic NEET proteins uncovers a link between a key gene duplication event and the evolution of vertebrates. Sci Rep. 2017 02 16; 7:42571. Inupakutika MA, Sengupta S, Nechushtai R, Jennings PA, Onuchic JN, Azad RK, Padilla P, Mittler R. PMID: 28205535.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    23. Pierced Lasso Topology Controls Function in Leptin. J Phys Chem B. 2017 02 02; 121(4):706-718. Haglund E, Pilko A, Wollman R, Jennings PA, Onuchic JN. PMID: 28035835.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    24. Breast cancer tumorigenicity is dependent on high expression levels of NAF-1 and the lability of its Fe-S clusters. Proc Natl Acad Sci U S A. 2016 09 27; 113(39):10890-5. Darash-Yahana M, Pozniak Y, Lu M, Sohn YS, Karmi O, Tamir S, Bai F, Song L, Jennings PA, Pikarsky E, Geiger T, Onuchic JN, Mittler R, Nechushtai R. PMID: 27621439.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    25. Gambogic acid identifies an isoform-specific druggable pocket in the middle domain of Hsp90ß. Proc Natl Acad Sci U S A. 2016 08 16; 113(33):E4801-9. Yim KH, Prince TL, Qu S, Bai F, Jennings PA, Onuchic JN, Theodorakis EA, Neckers L. PMID: 27466407.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    26. Untangling the Influence of a Protein Knot on Folding. Biophys J. 2016 Mar 08; 110(5):1044-51. Capraro DT, Jennings PA. PMID: 26958882.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    27. Geometrical Frustration in Interleukin-33 Decouples the Dynamics of the Functional Element from the Folding Transition State Ensemble. PLoS One. 2015; 10(12):e0144067. Fisher KM, Haglund E, Noel JK, Hailey KL, Onuchic JN, Jennings PA. PMID: 26630011.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    28. Activation of apoptosis in NAF-1-deficient human epithelial breast cancer cells. J Cell Sci. 2016 Jan 01; 129(1):155-65. Holt SH, Darash-Yahana M, Sohn YS, Song L, Karmi O, Tamir S, Michaeli D, Luo Y, Paddock ML, Jennings PA, Onuchic JN, Azad RK, Pikarsky E, Cabantchik IZ, Nechushtai R, Mittler R. PMID: 26621032.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    29. Cancer-Related NEET Proteins Transfer 2Fe-2S Clusters to Anamorsin, a Protein Required for Cytosolic Iron-Sulfur Cluster Biogenesis. PLoS One. 2015; 10(10):e0139699. Lipper CH, Paddock ML, Onuchic JN, Mittler R, Nechushtai R, Jennings PA. PMID: 26448442.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    30. Nuclear protein kinase CLK1 uses a non-traditional docking mechanism to select physiological substrates. Biochem J. 2015 Dec 15; 472(3):329-38. Keshwani MM, Hailey KL, Aubol BE, Fattet L, McGlone ML, Jennings PA, Adams JA. PMID: 26443864.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    31. Heterogeneous side chain conformation highlights a network of interactions implicated in hysteresis of the knotted protein, minimal tied trefoil. J Phys Condens Matter. 2015 Sep 09; 27(35):354108. Burban DJ, Haglund E, Capraro DT, Jennings PA. PMID: 26291198.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    32. Correction: Theoretical Insights Reveal Novel Motions in Csk's SH3 Domain That Control Kinase Activation. PLoS One. 2015; 10(7):e0133801. Barkho S, Pierce LC, Li S, Adams JA, Jennings PA. PMID: 26191813.
      View in: PubMed   Mentions:    Fields:    
    33. Dual-Mode HDAC Prodrug for Covalent Modification and Subsequent Inhibitor Release. J Med Chem. 2015 Jun 11; 58(11):4812-21. Daniel KB, Sullivan ED, Chen Y, Chan JC, Jennings PA, Fierke CA, Cohen SM. PMID: 25974739.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    34. Theoretical Insights Reveal Novel Motions in Csk's SH3 Domain That Control Kinase Activation. PLoS One. 2015; 10(6):e0127724. Barkho S, Pierce LC, Li S, Adams JA, Jennings PA. PMID: 26030592.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    35. The Fe-S cluster-containing NEET proteins mitoNEET and NAF-1 as chemotherapeutic targets in breast cancer. Proc Natl Acad Sci U S A. 2015 Mar 24; 112(12):3698-703. Bai F, Morcos F, Sohn YS, Darash-Yahana M, Rezende CO, Lipper CH, Paddock ML, Song L, Luo Y, Holt SH, Tamir S, Theodorakis EA, Jennings PA, Onuchic JN, Mittler R, Nechushtai R. PMID: 25762074.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    36. Conserved proline-directed phosphorylation regulates SR protein conformation and splicing function. Biochem J. 2015 Mar 01; 466(2):311-22. Keshwani MM, Aubol BE, Fattet L, Ma CT, Qiu J, Jennings PA, Fu XD, Adams JA. PMID: 25529026.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    37. Anticipatory sensitization to repeated stressors: the role of initial cortisol reactivity and meditation/emotion skills training. Psychoneuroendocrinology. 2015 Feb; 52:229-38. Turan B, Foltz C, Cavanagh JF, Wallace BA, Cullen M, Rosenberg EL, Jennings PA, Ekman P, Kemeny ME. PMID: 25497480.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    38. Structure-function analysis of NEET proteins uncovers their role as key regulators of iron and ROS homeostasis in health and disease. Biochim Biophys Acta. 2015 Jun; 1853(6):1294-315. Tamir S, Paddock ML, Darash-Yahana-Baram M, Holt SH, Sohn YS, Agranat L, Michaeli D, Stofleth JT, Lipper CH, Morcos F, Cabantchik IZ, Onuchic JN, Jennings PA, Mittler R, Nechushtai R. PMID: 25448035.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    39. Pierced Lasso Bundles are a new class of knot-like motifs. PLoS Comput Biol. 2014 Jun; 10(6):e1003613. Haglund E, Sulkowska JI, Noel JK, Lammert H, Onuchic JN, Jennings PA. PMID: 24945798.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    40. A point mutation in the [2Fe-2S] cluster binding region of the NAF-1 protein (H114C) dramatically hinders the cluster donor properties. Acta Crystallogr D Biol Crystallogr. 2014 Jun; 70(Pt 6):1572-8. Tamir S, Eisenberg-Domovich Y, Conlan AR, Stofleth JT, Lipper CH, Paddock ML, Mittler R, Jennings PA, Livnah O, Nechushtai R. PMID: 24914968.
      View in: PubMed   Mentions: 9     Fields:    
    41. Integrated strategy reveals the protein interface between cancer targets Bcl-2 and NAF-1. Proc Natl Acad Sci U S A. 2014 Apr 08; 111(14):5177-82. Tamir S, Rotem-Bamberger S, Katz C, Morcos F, Hailey KL, Zuris JA, Wang C, Conlan AR, Lipper CH, Paddock ML, Mittler R, Onuchic JN, Jennings PA, Friedler A, Nechushtai R. PMID: 24706857.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    42. Proximity-enabled protein crosslinking through genetically encoding haloalkane unnatural amino acids. Angew Chem Int Ed Engl. 2014 Feb 17; 53(8):2190-3. Xiang Z, Lacey VK, Ren H, Xu J, Burban DJ, Jennings PA, Wang L. PMID: 24449339.
      View in: PubMed   Mentions: 22     Fields:    Translation:Cells
    43. Improving classroom learning environments by Cultivating Awareness and Resilience in Education (CARE): results of a randomized controlled trial. Sch Psychol Q. 2013 Dec; 28(4):374-390. Jennings PA, Frank JL, Snowberg KE, Coccia MA, Greenberg MT. PMID: 24015983.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    44. Distal loop flexibility of a regulatory domain modulates dynamics and activity of C-terminal SRC kinase (csk). PLoS Comput Biol. 2013; 9(9):e1003188. Barkho S, Pierce LC, McGlone ML, Li S, Woods VL, Walker RC, Adams JA, Jennings PA. PMID: 24039559.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    45. Altered backbone and side-chain interactions result in route heterogeneity during the folding of interleukin-1ß (IL-1ß). Biophys J. 2013 Aug 20; 105(4):975-83. Capraro DT, Lammert H, Heidary DK, Roy M, Gross LA, Onuchic JN, Jennings PA. PMID: 23972849.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    46. NAF-1 and mitoNEET are central to human breast cancer proliferation by maintaining mitochondrial homeostasis and promoting tumor growth. Proc Natl Acad Sci U S A. 2013 Sep 03; 110(36):14676-81. Sohn YS, Tamir S, Song L, Michaeli D, Matouk I, Conlan AR, Harir Y, Holt SH, Shulaev V, Paddock ML, Hochberg A, Cabanchick IZ, Onuchic JN, Jennings PA, Nechushtai R, Mittler R. PMID: 23959881.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    47. Nutrient-deprivation autophagy factor-1 (NAF-1): biochemical properties of a novel cellular target for anti-diabetic drugs. PLoS One. 2013; 8(5):e61202. Tamir S, Zuris JA, Agranat L, Lipper CH, Conlan AR, Michaeli D, Harir Y, Paddock ML, Mittler R, Cabantchik ZI, Jennings PA, Nechushtai R. PMID: 23717386.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    48. Allosteric switching of agonist/antagonist activity by a single point mutation in the interluekin-1 receptor antagonist, IL-1Ra. J Mol Biol. 2013 Jul 10; 425(13):2382-92. Hailey KL, Capraro DT, Barkho S, Jennings PA. PMID: 23499887.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    49. Learning from cancer how to defeat bacteria. Proc Natl Acad Sci U S A. 2013 Feb 26; 110(9):3212-3. Onuchic JN, Jennings PA, Ben-Jacob E. PMID: 23407166.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    50. 2013 SYR Accepted Poster Abstracts. Int J Yoga Therap. 2013; 23(1):32-53. Bayley PJ, Isaac L, Kong JY, Adamson MM, Ashford JW, Mahoney LA, Beltran M, Brown-Elhillali A, Held A, Ajayi A, Belcher H, Bond A, Mason H, Lemaster C, Shaw S, Mullin C, Holick E, Saper R, Braun TD, Riley KE, Park CL, Trehern AE, Davis MB, Mastronardi EL, Butzer B, Khalsa SB, Shorter SM, Reinhardt KM, Cope S, Cheung C, Justice C, Wyman J, Cook-Cottone CP, Daly LA, Haden SC, Hagins M, Danhauer SC, Griffin LP, Avis NE, Sohl SJ, Lawrence J, Jesse MT, Addington EL, Messino MJ, Giguere JK, Lucas SL, Wiliford SK, Shaw E, de Manincor M, Bensoussan A, Smith C, Fahey P, Bourchier S, Desrochers DI, Viswanathan S, Partharasathy BR, Doherty K, Moye J, Walsh C, Pokaski-Azar J, Gosian J, Chapman J, King K, Sohl S, Danhauer S, Dunbar E, Gabriel MG, Huebner M, Hofmann SG, Khalsa SB, Gaskins RB, Jennings E, Thind H, Fava JL, Hartman S, Bock BC, Gramann P, Haaz S, Bingham CO, Bartlett SJ, Hagins M, States R, Selfe T, Innes K, Harris AR, Jennings PA, Abenavoli RM, Katz DA, Hudecek KM, Greenberg MT, Jeter PE, Nkodo AF, Haaz S, Dagnelie G, Keosaian JE, Lemaster CM, Chao M, Saper RB, King KD, Gosian J, Doherty K, Walsh C, Pokaski Azar J, Chapman J, Danhauer SC, Moye J, Kinser P, Bourguignon C, Taylor A, Mahoney LA, Bayley PJ, Collery LM, Menzies-Toman D, Nilsson M, Frykman V, Noggle JJ, Braun T, Khalsa SB, Nosaka M, Okamura H, Fukatu N, Potts A, Weidknecht K, Coulombe S, Davies B, Ryan C, Day D, Reale J, Staples JK, Knoefel J, Herman C, Riley KE, Park CL, Bedesin EY, Stewart VM, Riley KE, Braun TD, Park CL, Pescatello LS, Davis MB, Trehern AE, Mastronardi EL, Rioux J, Rosen RK, Thind H, Gaskins R, Jennings E, Morrow K, Williams D, Bock B, Rousseau D, Jackson E, Schmid AA, Miller KK, Van Puymbroeck M, Debaun EL, Schalk N, Dierks TD, Altenburger P, Damush T, Williams LS, Selman L, Citron T, Howie-Esquivel J, McDermott K, Milic M, Donesky D, Shook A, Ruzic R, Galloway F, Van Puymbroeck M, Miller KK, Schalk N, Schmid AA, Ward LJ, Stebbings S, Sherman K, Cherkin D, Baxter GD, West JI, Duffy N, Liang B. PMID: 24016822.
      View in: PubMed   Mentions:    Fields:    
    51. Allosteric control in a metalloprotein dramatically alters function. Proc Natl Acad Sci U S A. 2013 Jan 15; 110(3):948-53. Baxter EL, Zuris JA, Wang C, Vo PL, Axelrod HL, Cohen AE, Paddock ML, Nechushtai R, Onuchic JN, Jennings PA. PMID: 23271805.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    52. Hysteresis as a Marker for Complex, Overlapping Landscapes in Proteins. J Phys Chem Lett. 2013 Jan 03; 4(1):180-188. Andrews BT, Capraro DT, Sulkowska JI, Onuchic JN, Jennings PA. PMID: 23525263.
      View in: PubMed   Mentions: 11     Fields:    
    53. The unique cysteine knot regulates the pleotropic hormone leptin. PLoS One. 2012; 7(9):e45654. Haglund E, Sulkowska JI, He Z, Feng GS, Jennings PA, Onuchic JN. PMID: 23029163.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    54. Substrate-specific reorganization of the conformational ensemble of CSK implicates novel modes of kinase function. PLoS Comput Biol. 2012; 8(9):e1002695. Jamros MA, Oliveira LC, Whitford PC, Onuchic JN, Adams JA, Jennings PA. PMID: 23028292.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    55. Folding circular permutants of IL-1ß: route selection driven by functional frustration. PLoS One. 2012; 7(6):e38512. Capraro DT, Gosavi S, Roy M, Onuchic JN, Jennings PA. PMID: 22693643.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    56. Characterization of Arabidopsis NEET reveals an ancient role for NEET proteins in iron metabolism. Plant Cell. 2012 May; 24(5):2139-54. Nechushtai R, Conlan AR, Harir Y, Song L, Yogev O, Eisenberg-Domovich Y, Livnah O, Michaeli D, Rosen R, Ma V, Luo Y, Zuris JA, Paddock ML, Cabantchik ZI, Jennings PA, Mittler R. PMID: 22562611.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    57. NADPH inhibits [2Fe-2S] cluster protein transfer from diabetes drug target MitoNEET to an apo-acceptor protein. J Biol Chem. 2012 Apr 06; 287(15):11649-55. Zuris JA, Ali SS, Yeh H, Nguyen TA, Nechushtai R, Paddock ML, Jennings PA. PMID: 22351774.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    58. Peptidyl-prolyl isomerase Pin1 controls down-regulation of conventional protein kinase C isozymes. J Biol Chem. 2012 Apr 13; 287(16):13262-78. Abrahamsen H, O'Neill AK, Kannan N, Kruse N, Taylor SS, Jennings PA, Newton AC. PMID: 22318721.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    59. Strand swapping regulates the iron-sulfur cluster in the diabetes drug target mitoNEET. Proc Natl Acad Sci U S A. 2012 Feb 07; 109(6):1955-60. Baxter EL, Jennings PA, Onuchic JN. PMID: 22308404.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    60. ß-Bulge triggers route-switching on the functional landscape of interleukin-1ß. Proc Natl Acad Sci U S A. 2012 Jan 31; 109(5):1490-3. Capraro DT, Roy M, Onuchic JN, Gosavi S, Jennings PA. PMID: 22307602.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    61. Mindfulness for adolescents: a promising approach to supporting emotion regulation and preventing risky behavior. New Dir Youth Dev. 2012; 2012(136):111-26, 11. Broderick PC, Jennings PA. PMID: 23359447.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    62. Contemplative/emotion training reduces negative emotional behavior and promotes prosocial responses. Emotion. 2012 Apr; 12(2):338-50. Kemeny ME, Foltz C, Cavanagh JF, Cullen M, Giese-Davis J, Jennings P, Rosenberg EL, Gillath O, Shaver PR, Wallace BA, Ekman P. PMID: 22148989.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    63. Facile transfer of [2Fe-2S] clusters from the diabetes drug target mitoNEET to an apo-acceptor protein. Proc Natl Acad Sci U S A. 2011 Aug 09; 108(32):13047-52. Zuris JA, Harir Y, Conlan AR, Shvartsman M, Michaeli D, Tamir S, Paddock ML, Onuchic JN, Mittler R, Cabantchik ZI, Jennings PA, Nechushtai R. PMID: 21788481.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    64. Mutation of the His ligand in mitoNEET stabilizes the 2Fe-2S cluster despite conformational heterogeneity in the ligand environment. Acta Crystallogr D Biol Crystallogr. 2011 Jun; 67(Pt 6):516-23. Conlan AR, Paddock ML, Homer C, Axelrod HL, Cohen AE, Abresch EC, Zuris JA, Nechushtai R, Jennings PA. PMID: 21636891.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    65. Regulating SR protein phosphorylation through regions outside the kinase domain of SRPK1. J Mol Biol. 2011 Jul 01; 410(1):131-45. Plocinik RM, Li S, Liu T, Hailey KL, Whitesides J, Whitehouse J, Ma CT, Fu XD, Gosh G, Woods VL, Jennings PA, Adams JA. PMID: 21600902.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    66. Interdomain communication revealed in the diabetes drug target mitoNEET. Proc Natl Acad Sci U S A. 2011 Mar 29; 108(13):5266-71. Baxter EL, Jennings PA, Onuchic JN. PMID: 21402934.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    67. Allostery in the ferredoxin protein motif does not involve a conformational switch. Proc Natl Acad Sci U S A. 2011 Feb 08; 108(6):2240-5. Nechushtai R, Lammert H, Michaeli D, Eisenberg-Domovich Y, Zuris JA, Luca MA, Capraro DT, Fish A, Shimshon O, Roy M, Schug A, Whitford PC, Livnah O, Onuchic JN, Jennings PA. PMID: 21266547.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    68. Engineering the redox potential over a wide range within a new class of FeS proteins. J Am Chem Soc. 2010 Sep 29; 132(38):13120-2. Zuris JA, Halim DA, Conlan AR, Abresch EC, Nechushtai R, Paddock ML, Jennings PA. PMID: 20812736.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    69. Proteins at work: a combined small angle X-RAY scattering and theoretical determination of the multiple structures involved on the protein kinase functional landscape. J Biol Chem. 2010 Nov 12; 285(46):36121-8. Jamros MA, Oliveira LC, Whitford PC, Onuchic JN, Adams JA, Blumenthal DK, Jennings PA. PMID: 20801888.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    70. Structure and activity of CPNGRC: a modified CD13/APN peptidic homing motif. Chem Biol Drug Des. 2010 Jun; 75(6):551-62. Plesniak LA, Salzameda B, Hinderberger H, Regan E, Kahn J, Mills SA, Teriete P, Yao Y, Jennings P, Marassi F, Adams JA. PMID: 20374250.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    71. Binding of histidine in the (Cys)3(His)1-coordinated [2Fe-2S] cluster of human mitoNEET. J Am Chem Soc. 2010 Feb 17; 132(6):2037-49. Dicus MM, Conlan A, Nechushtai R, Jennings PA, Paddock ML, Britt RD, Stoll S. PMID: 20099820.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    72. Redox characterization of the FeS protein MitoNEET and impact of thiazolidinedione drug binding. Biochemistry. 2009 Nov 03; 48(43):10193-5. Bak DW, Zuris JA, Paddock ML, Jennings PA, Elliott SJ. PMID: 19791753.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    73. Pro-interleukin (IL)-1beta shares a core region of stability as compared with mature IL-1beta while maintaining a distinctly different configurational landscape: a comparative hydrogen/deuterium exchange mass spectrometry study. J Biol Chem. 2009 Sep 18; 284(38):26137-48. Hailey KL, Li S, Andersen MD, Roy M, Woods VL, Jennings PA. PMID: 19592498.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    74. Crystal structure of Miner1: The redox-active 2Fe-2S protein causative in Wolfram Syndrome 2. J Mol Biol. 2009 Sep 11; 392(1):143-53. Conlan AR, Axelrod HL, Cohen AE, Abresch EC, Zuris J, Yee D, Nechushtai R, Jennings PA, Paddock ML. PMID: 19580816.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    75. Chromophore packing leads to hysteresis in GFP. J Mol Biol. 2009 Sep 11; 392(1):218-27. Andrews BT, Roy M, Jennings PA. PMID: 19577576.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    76. The novel 2Fe-2S outer mitochondrial protein mitoNEET displays conformational flexibility in its N-terminal cytoplasmic tethering domain. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Jul 01; 65(Pt 7):654-9. Conlan AR, Paddock ML, Axelrod HL, Cohen AE, Abresch EC, Wiley S, Roy M, Nechushtai R, Jennings PA. PMID: 19574633.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    77. Resonance Raman studies of the (His)(Cys)3 2Fe-2S cluster of MitoNEET: comparison to the (Cys)4 mutant and implications of the effects of pH on the labile metal center. Biochemistry. 2009 Jun 09; 48(22):4747-52. Tirrell TF, Paddock ML, Conlan AR, Smoll EJ, Nechushtai R, Jennings PA, Kim JE. PMID: 19388667.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    78. Ligand-induced global transitions in the catalytic domain of protein kinase A. Proc Natl Acad Sci U S A. 2009 Mar 03; 106(9):3023-8. Hyeon C, Jennings PA, Adams JA, Onuchic JN. PMID: 19204278.
      View in: PubMed   Mentions: 41     Fields:    Translation:Cells
    79. Backtracking on the folding landscape of the beta-trefoil protein interleukin-1beta? Proc Natl Acad Sci U S A. 2008 Sep 30; 105(39):14844-8. Capraro DT, Roy M, Onuchic JN, Jennings PA. PMID: 18806223.
      View in: PubMed   Mentions: 31     Fields:    Translation:Cells
    80. The dual-basin landscape in GFP folding. Proc Natl Acad Sci U S A. 2008 Aug 26; 105(34):12283-8. Andrews BT, Gosavi S, Finke JM, Onuchic JN, Jennings PA. PMID: 18713871.
      View in: PubMed   Mentions: 26     Fields:    Translation:Cells
    81. Adaptable molecular interactions guide phosphorylation of the SR protein ASF/SF2 by SRPK1. J Mol Biol. 2008 Oct 17; 382(4):894-909. Hagopian JC, Ma CT, Meade BR, Albuquerque CP, Ngo JC, Ghosh G, Jennings PA, Fu XD, Adams JA. PMID: 18687337.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    82. Extracting function from a beta-trefoil folding motif. Proc Natl Acad Sci U S A. 2008 Jul 29; 105(30):10384-9. Gosavi S, Whitford PC, Jennings PA, Onuchic JN. PMID: 18650393.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    83. Contemplative education and youth development. New Dir Youth Dev. 2008; 2008(118):101-5, 9. Jennings PA. PMID: 18642301.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    84. Transferred NOE and saturation transfer difference NMR studies of novobiocin binding to EnvZ suggest binding mode similar to DNA gyrase. Chem Biol Drug Des. 2008 Jan; 71(1):28-35. Plesniak LA, Botsch K, Leibrand M, Kelly M, Sem D, Adams JA, Jennings P. PMID: 18093089.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    85. MitoNEET is a uniquely folded 2Fe 2S outer mitochondrial membrane protein stabilized by pioglitazone. Proc Natl Acad Sci U S A. 2007 Sep 04; 104(36):14342-7. Paddock ML, Wiley SE, Axelrod HL, Cohen AE, Roy M, Abresch EC, Capraro D, Murphy AN, Nechushtai R, Dixon JE, Jennings PA. PMID: 17766440.
      View in: PubMed   Mentions: 92     Fields:    Translation:HumansCells
    86. The rough energy landscape of superfolder GFP is linked to the chromophore. J Mol Biol. 2007 Oct 19; 373(2):476-90. Andrews BT, Schoenfish AR, Roy M, Waldo G, Jennings PA. PMID: 17822714.
      View in: PubMed   Mentions: 29     Fields:    Translation:Cells
    87. SOCRATES Episode II (synopsis of Cochrane reviews applicable to emergency services Episode II): the return of Series III. Emerg Med J. 2007 Jul; 24(7):489-91. Gilligan P, Pountney A, Wilson B, Mehigan C, Kidney E, Jennings P, Cooper J, Hegarty D, Lee J, Khan A, Lumsden G, Godden D, Shepherd M, Allonby-Neve L, Broderick A, Carr S, Wilson S, O' Sullivan J. PMID: 17582042.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsPHPublic Health
    88. The outer mitochondrial membrane protein mitoNEET contains a novel redox-active 2Fe-2S cluster. J Biol Chem. 2007 Aug 17; 282(33):23745-9. Wiley SE, Paddock ML, Abresch EC, Gross L, van der Geer P, Nechushtai R, Murphy AN, Jennings PA, Dixon JE. PMID: 17584744.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    89. Equilibrium unfolding of the poly(glutamic acid)20 helix. Biopolymers. 2007 Jun 15; 86(3):193-211. Finke JM, Jennings PA, Lee JC, Onuchic JN, Winkler JR. PMID: 17370320.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    90. SOCRATES episode II (synopsis of cochrane reviews applicable to emergency services episode II): the return of the series II. Emerg Med J. 2007 Feb; 24(2):115-7. Gilligan P, Lee J, Khan A, Jennings P, Cooper J, Hegarty D, Lumsden G, Godden D, Pountney A, Wilson B, Shepherd M, Allonby-Neve L, Mehigan C, Kidney E, Broderick A, Carr S, Wilson S, O'Sullivan J. PMID: 17251619.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    91. A dynamic mechanism for AKAP binding to RII isoforms of cAMP-dependent protein kinase. Mol Cell. 2006 Nov 03; 24(3):397-408. Kinderman FS, Kim C, von Daake S, Ma Y, Pham BQ, Spraggon G, Xuong NH, Jennings PA, Taylor SS. PMID: 17081990.
      View in: PubMed   Mentions: 103     Fields:    Translation:AnimalsCells
    92. A novel disulfide bond in the SH2 Domain of the C-terminal Src kinase controls catalytic activity. J Mol Biol. 2007 Feb 02; 365(5):1460-8. Mills JE, Whitford PC, Shaffer J, Onuchic JN, Adams JA, Jennings PA. PMID: 17137590.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    93. Exploring biomolecular machines: energy landscape control of biological reactions. Philos Trans R Soc Lond B Biol Sci. 2006 Aug 29; 361(1472):1439-43. Onuchic JN, Kobayashi C, Miyashita O, Jennings P, Baldridge KK. PMID: 16873130.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    94. Multiple routes lead to the native state in the energy landscape of the beta-trefoil family. Proc Natl Acad Sci U S A. 2006 Jul 05; 103(27):10254-10258. Chavez LL, Gosavi S, Jennings PA, Onuchic JN. PMID: 16801558.
      View in: PubMed   Mentions: 31     Fields:    Translation:Cells
    95. Structural evaluation of a novel pro-apoptotic peptide coupled to CNGRC tumor homing sequence by NMR. Chem Biol Drug Des. 2006 Jun; 67(6):417-24. Sandoval CM, Geierstanger BH, Fujimura S, Balatbat C, Williams T, de Unamuno J, Whiles-Lillig JA, Ellerby LM, Ellerby HM, Jennings P, Plesniak LA. PMID: 16882316.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    96. Topological frustration and the folding of interleukin-1 beta. J Mol Biol. 2006 Mar 31; 357(3):986-96. Gosavi S, Chavez LL, Jennings PA, Onuchic JN. PMID: 16469330.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansCells
    97. Distinct interaction modes of an AKAP bound to two regulatory subunit isoforms of protein kinase A revealed by amide hydrogen/deuterium exchange. Protein Sci. 2005 Dec; 14(12):2982-92. Burns-Hamuro LL, Hamuro Y, Kim JS, Sigala P, Fayos R, Stranz DD, Jennings PA, Taylor SS, Woods VL. PMID: 16260760.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    98. Long-range coupling between separate docking sites in interleukin-1beta. J Mol Biol. 2005 Nov 11; 353(5):1187-98. Heidary DK, Roy M, Daumy GO, Cong Y, Jennings PA. PMID: 16216268.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    99. Coupling phosphoryl transfer and substrate interactions in protein kinases. Biochim Biophys Acta. 2005 Dec 30; 1754(1-2):191-9. Lieser SA, Aubol BE, Wong L, Jennings PA, Adams JA. PMID: 16213199.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    100. Coupled motions in the SH2 and kinase domains of Csk control Src phosphorylation. J Mol Biol. 2005 Aug 05; 351(1):131-43. Wong L, Lieser SA, Miyashita O, Miller M, Tasken K, Onuchic JN, Adams JA, Woods VL, Jennings PA. PMID: 16002086.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    101. Temperature, media, and point of induction affect the N-terminal processing of interleukin-1beta. Protein Expr Purif. 2005 May; 41(1):45-52. Covalt JC, Cao TB, Magdaroag JR, Gross LA, Jennings PA. PMID: 15802220.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    102. The native energy landscape for interleukin-1beta. Modulation of the population ensemble through native-state topology. J Mol Biol. 2005 Apr 29; 348(2):335-47. Roy M, Chavez LL, Finke JM, Heidary DK, Onuchic JN, Jennings PA. PMID: 15811372.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    103. Control of protein functional dynamics by peptide linkers. Biopolymers. 2005; 80(6):736-46. Wriggers W, Chakravarty S, Jennings PA. PMID: 15880774.
      View in: PubMed   Mentions: 37     Fields:    Translation:Cells
    104. Self-transcendence: conceptualization and measurement. Int J Aging Hum Dev. 2005; 60(2):127-43. Levenson MR, Jennings PA, Aldwin CM, Shiraishi RW. PMID: 15801386.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    105. Tumor imaging by means of proteolytic activation of cell-penetrating peptides. Proc Natl Acad Sci U S A. 2004 Dec 21; 101(51):17867-72. Jiang T, Olson ES, Nguyen QT, Roy M, Jennings PA, Tsien RY. PMID: 15601762.
      View in: PubMed   Mentions: 221     Fields:    Translation:HumansAnimalsCells
    106. Using chemical exchange to assign non-covalent protein complexes in slow exchange with the free state: enhanced resolution and efficient signal editing. J Biomol NMR. 2004 Oct; 30(2):155-61. Rodríguez JC, Jennings PA, Melacini G. PMID: 15557802.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    107. Orientation and helical conformation of a tissue-specific hunter-killer peptide in micelles. Protein Sci. 2004 Aug; 13(8):1988-96. Plesniak LA, Parducho JI, Ziebart A, Geierstanger BH, Whiles JA, Melacini G, Jennings PA. PMID: 15273301.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    108. Dynamic coupling between the SH2 domain and active site of the COOH terminal Src kinase, Csk. J Mol Biol. 2004 Jul 30; 341(1):93-106. Wong L, Lieser S, Chie-Leon B, Miyashita O, Aubol B, Shaffer J, Onuchic JN, Jennings PA, Woods VL, Adams JA. PMID: 15312765.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    109. Communication pathways between the nucleotide pocket and distal regulatory sites in protein kinases. Acc Chem Res. 2004 May; 37(5):304-11. Wong L, Jennings PA, Adams JA. PMID: 15147171.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    110. The pH dependence of stability of the activation helix and the catalytic site of GART. Biophys Chem. 2003 Sep; 105(2-3):279-91. Morikis D, Elcock AH, Jennings PA, McCammon JA. PMID: 14499900.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    111. Related protein-protein interaction modules present drastically different surface topographies despite a conserved helical platform. J Mol Biol. 2003 Jul 25; 330(5):1117-29. Banky P, Roy M, Newlon MG, Morikis D, Haste NM, Taylor SS, Jennings PA. PMID: 12860132.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    112. Real-time NMR kinetic studies provide global and residue-specific information on the non-cooperative unfolding of the beta-trefoil protein, interleukin-1beta. J Mol Biol. 2003 May 02; 328(3):693-703. Roy M, Jennings PA. PMID: 12706726.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    113. Bioinformatic design of A-kinase anchoring protein-in silico: a potent and selective peptide antagonist of type II protein kinase A anchoring. Proc Natl Acad Sci U S A. 2003 Apr 15; 100(8):4445-50. Alto NM, Soderling SH, Hoshi N, Langeberg LK, Fayos R, Jennings PA, Scott JD. PMID: 12672969.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansCells
    114. The solvent in CNBr cleavage reactions determines the fragmentation efficiency of ketosteroid isomerase fusion proteins used in the production of recombinant peptides. Protein Expr Purif. 2003 Apr; 28(2):224-31. Rodríguez JC, Wong L, Jennings PA. PMID: 12699685.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    115. Induction of flexibility through protein-protein interactions. J Biol Chem. 2003 May 16; 278(20):18581-7. Fayos R, Melacini G, Newlon MG, Burns L, Scott JD, Jennings PA. PMID: 12604595.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    116. Use of multiple anomalous dispersion to phase highly merohedrally twinned crystals of interleukin-1beta. Acta Crystallogr D Biol Crystallogr. 2003 Feb; 59(Pt 2):290-8. Rudolph MG, Kelker MS, Schneider TR, Yeates TO, Oseroff V, Heidary DK, Jennings PA, Wilson IA. PMID: 12554939.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    117. Interleukin-1 beta folding between pH 5 and 7: experimental evidence for three-state folding behavior and robust transition state positions late in folding. Biochemistry. 2002 Dec 17; 41(50):15056-67. Finke JM, Jennings PA. PMID: 12475255.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    118. Probing the nucleotide binding domain of the osmoregulator EnvZ using fluorescent nucleotide derivatives. Biochemistry. 2002 Nov 26; 41(47):13876-82. Plesniak L, Horiuchi Y, Sem D, Meinenger D, Stiles L, Shaffer J, Jennings PA, Adams JA. PMID: 12437344.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    119. Phosphorylation driven motions in the COOH-terminal Src kinase, CSK, revealed through enhanced hydrogen-deuterium exchange and mass spectrometry (DXMS). J Mol Biol. 2002 Nov 08; 323(5):871-81. Hamuro Y, Wong L, Shaffer J, Kim JS, Stranz DD, Jennings PA, Woods VL, Adams JA. PMID: 12417200.
      View in: PubMed   Mentions: 32     Fields:    Translation:Cells
    120. Effect of chemical exchange on radiation damping in aqueous solutions of the osmolyte glycine. J Am Chem Soc. 2002 Jun 05; 124(22):6240-1. Rodríguez JC, Jennings PA, Melacini G. PMID: 12033843.
      View in: PubMed   Mentions: 3     Fields:    
    121. Electrostatic properties of the structure of the docking and dimerization domain of protein kinase A IIalpha. Eur J Biochem. 2002 Apr; 269(8):2040-51. Morikis D, Roy M, Newlon MG, Scott JD, Jennings PA. PMID: 11985580.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    122. Three topologically equivalent core residues affect the transition state ensemble in a protein folding reaction. J Mol Biol. 2002 Feb 22; 316(3):789-98. Heidary DK, Jennings PA. PMID: 11866531.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    123. The structural basis of compstatin activity examined by structure-function-based design of peptide analogs and NMR. J Biol Chem. 2002 Apr 26; 277(17):14942-53. Morikis D, Roy M, Sahu A, Troganis A, Jennings PA, Tsokos GC, Lambris JD. PMID: 11847226.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    124. Native-state conformational dynamics of GART: a regulatory pH-dependent coil-helix transition examined by electrostatic calculations. Protein Sci. 2001 Nov; 10(11):2363-78. Morikis D, Elcock AH, Jennings PA, McCammon JA. PMID: 11604542.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    125. Proton transfer dynamics of GART: the pH-dependent catalytic mechanism examined by electrostatic calculations. Protein Sci. 2001 Nov; 10(11):2379-92. Morikis D, Elcock AH, Jennings PA, McCammon JA. PMID: 11604543.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    126. A universal protein-protein interaction motif in the eubacterial DNA replication and repair systems. Proc Natl Acad Sci U S A. 2001 Sep 25; 98(20):11627-32. Dalrymple BP, Kongsuwan K, Wijffels G, Dixon NE, Jennings PA. PMID: 11573000.
      View in: PubMed   Mentions: 118     Fields:    Translation:Cells
    127. Prediction of folding mechanism for circular-permuted proteins. J Mol Biol. 2001 Aug 24; 311(4):879-90. Clementi C, Jennings PA, Onuchic JN. PMID: 11518537.
      View in: PubMed   Mentions: 25     Fields:    Translation:Cells
    128. Early aggregated States in the folding of interleukin-1ß. J Biol Phys. 2001 Jun; 27(2-3):119-31. Finke JM, Jennings PA. PMID: 23345738.
      View in: PubMed   Mentions: 7     Fields:    
    129. A novel mechanism of PKA anchoring revealed by solution structures of anchoring complexes. EMBO J. 2001 Apr 02; 20(7):1651-62. Newlon MG, Roy M, Morikis D, Carr DW, Westphal R, Scott JD, Jennings PA. PMID: 11285229.
      View in: PubMed   Mentions: 63     Fields:    Translation:Cells
    130. Core and surface mutations affect folding kinetics, stability and cooperativity in IL-1 beta: does alteration in buried water play a role? J Mol Biol. 2001 Mar 23; 307(2):657-69. Covalt JC, Roy M, Jennings PA. PMID: 11254388.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    131. Structural characterization of protein kinase A as a function of nucleotide binding. Hydrogen-deuterium exchange studies using matrix-assisted laser desorption ionization-time of flight mass spectrometry detection. J Biol Chem. 2001 Apr 27; 276(17):14204-11. Andersen MD, Shaffer J, Jennings PA, Adams JA. PMID: 11278927.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    132. Commitment to folded and aggregated states occurs late in interleukin-1 beta folding. Biochemistry. 2000 Dec 19; 39(50):15633-42. Finke JM, Gross LA, Ho HM, Sept D, Zimm BH, Jennings PA. PMID: 11112552.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    133. Isoform-specific differences between the type Ialpha and IIalpha cyclic AMP-dependent protein kinase anchoring domains revealed by solution NMR. J Biol Chem. 2000 Nov 10; 275(45):35146-52. Banky P, Newlon MG, Roy M, Garrod S, Taylor SS, Jennings PA. PMID: 10899163.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    134. An essential intermediate in the folding of dihydrofolate reductase. Proc Natl Acad Sci U S A. 2000 May 23; 97(11):5866-70. Heidary DK, O'Neill JC, Roy M, Jennings PA. PMID: 10811909.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    135. How native-state topology affects the folding of dihydrofolate reductase and interleukin-1beta. Proc Natl Acad Sci U S A. 2000 May 23; 97(11):5871-6. Clementi C, Jennings PA, Onuchic JN. PMID: 10811910.
      View in: PubMed   Mentions: 63     Fields:    Translation:Cells
    136. Aggregation events occur prior to stable intermediate formation during refolding of interleukin 1beta. Biochemistry. 2000 Jan 25; 39(3):575-83. Finke JM, Roy M, Zimm BH, Jennings PA. PMID: 10642182.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    137. The molecular basis for protein kinase A anchoring revealed by solution NMR. Nat Struct Biol. 1999 Mar; 6(3):222-7. Newlon MG, Roy M, Morikis D, Hausken ZE, Coghlan V, Scott JD, Jennings PA. PMID: 10074940.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    138. Cloning of a Lysobacter enzymogenes gene that encodes an arginyl endopeptidase (endoproteinase Arg-C). Biochim Biophys Acta. 1998 Dec 22; 1443(3):369-74. Wright DS, Graham LD, Jennings PA. PMID: 9878833.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    139. Speeding along the protein folding highway, are we reading the signs correctly? Nat Struct Biol. 1998 Oct; 5(10):846-8. Jennings PA. PMID: 9783738.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    140. A pH-dependent stabilization of an active site loop observed from low and high pH crystal structures of mutant monomeric glycinamide ribonucleotide transformylase at 1.8 to 1.9 A. J Mol Biol. 1998 Aug 21; 281(3):485-99. Su Y, Yamashita MM, Greasley SE, Mullen CA, Shim JH, Jennings PA, Benkovic SJ, Wilson IA. PMID: 9698564.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    141. A single mutation disrupts the pH-dependent dimerization of glycinamide ribonucleotide transformylase. J Mol Biol. 1998 Mar 06; 276(4):819-27. Mullen CA, Jennings PA. PMID: 9500916.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    142. Folding pathway of interleukin-1 beta. Nat Struct Biol. 1998 Jan; 5(1):11. Jennings P, Roy M, Heidary D, Gross L. PMID: 9437419.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    143. Populating the equilibrium molten globule state of apomyoglobin under conditions suitable for structural characterization by NMR. FEBS Lett. 1997 Nov 03; 417(1):92-6. Eliezer D, Jennings PA, Dyson HJ, Wright PE. PMID: 9395082.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    144. The A-kinase anchoring domain of type IIalpha cAMP-dependent protein kinase is highly helical. J Biol Chem. 1997 Sep 19; 272(38):23637-44. Newlon MG, Roy M, Hausken ZE, Scott JD, Jennings PA. PMID: 9295304.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    145. Conformational changes induced in Hoxb-8/Pbx-1 heterodimers in solution and upon interaction with specific DNA. Mol Cell Biol. 1997 Sep; 17(9):5369-76. Sánchez M, Jennings PA, Murre C. PMID: 9271414.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    146. Evidence for an obligatory intermediate in the folding of interleukin-1 beta. Nat Struct Biol. 1997 Sep; 4(9):725-31. Heidary DK, Gross LA, Roy M, Jennings PA. PMID: 9303000.
      View in: PubMed   Mentions: 27     Fields:    Translation:Cells
    147. Glycinamide ribonucleotide transformylase undergoes pH-dependent dimerization. J Mol Biol. 1996 Oct 11; 262(5):746-55. Mullen CA, Jennings PA. PMID: 8876651.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    148. The AD1 transactivation domain of E2A contains a highly conserved helix which is required for its activity in both Saccharomyces cerevisiae and mammalian cells. Mol Cell Biol. 1996 Jan; 16(1):121-9. Massari ME, Jennings PA, Murre C. PMID: 8524288.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    149. Overexpression of myoglobin and assignment of its amide, C alpha and C beta resonances. J Biomol NMR. 1995 Nov; 6(3):271-6. Jennings PA, Stone MJ, Wright PE. PMID: 8520219.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    150. The radius of gyration of an apomyoglobin folding intermediate. Science. 1995 Oct 20; 270(5235):487-8. Eliezer D, Jennings PA, Wright PE, Doniach S, Hodgson KO, Tsuruta H. PMID: 7570004.
      View in: PubMed   Mentions: 32     Fields:    Translation:Cells
    151. In vitro activity of minimised hammerhead ribozymes. Nucleic Acids Res. 1995 Oct 11; 23(19):3922-7. Hendry P, McCall MJ, Santiago FS, Jennings PA. PMID: 7479037.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    152. Random mutagenesis of the substrate-binding site of a serine protease. A new library of alpha-lytic protease S1 mutants. Ann N Y Acad Sci. 1995 Mar 31; 750:10-4. Graham LD, Haggett KD, Hayes PJ, Schober PA, Jennings PA, Whittaker RG. PMID: 7785837.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    153. Calmodulin stabilizes an amphiphilic alpha-helix within RC3/neurogranin and GAP-43/neuromodulin only when Ca2+ is absent. J Biol Chem. 1995 Mar 24; 270(12):6741-50. Gerendasy DD, Herron SR, Jennings PA, Sutcliffe JG. PMID: 7896819.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    154. Development of nonpolar surfaces in the folding of Escherichia coli dihydrofolate reductase detected by 1-anilinonaphthalene-8-sulfonate binding. Biochemistry. 1994 Dec 27; 33(51):15250-8. Jones BE, Jennings PA, Pierre RA, Matthews CR. PMID: 7803387.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
    155. Using linkers to investigate the spatial separation of the conserved nucleotides A9 and G12 in the hammerhead ribozyme. Biochim Biophys Acta. 1994 Oct 18; 1219(2):405-12. Hendry P, Moghaddam MJ, McCall MJ, Jennings PA, Ebel S, Brown T. PMID: 7522573.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    156. Formation of a molten globule intermediate early in the kinetic folding pathway of apomyoglobin. Science. 1993 Nov 05; 262(5135):892-6. Jennings PA, Wright PE. PMID: 8235610.
      View in: PubMed   Mentions: 173     Fields:    Translation:Cells
    157. Random mutagenesis of the substrate-binding site of a serine protease can generate enzymes with increased activities and altered primary specificities. Biochemistry. 1993 Jun 22; 32(24):6250-8. Graham LD, Haggett KD, Jennings PA, Le Brocque DS, Whittaker RG, Schober PA. PMID: 8512935.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    158. A reexamination of the folding mechanism of dihydrofolate reductase from Escherichia coli: verification and refinement of a four-channel model. Biochemistry. 1993 Apr 13; 32(14):3783-9. Jennings PA, Finn BE, Jones BE, Matthews CR. PMID: 8466916.
      View in: PubMed   Mentions: 29     Fields:    Translation:Cells
    159. Mutant forms of beta-galactosidase with an altered requirement for magnesium ions. Protein Eng. 1992 Jul; 5(5):441-6. Dunn IS, Jennings PA. PMID: 1518793.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    160. Complex additivity of the effects of suppressor mutations in differing protein environments. Protein Eng. 1992 Jul; 5(5):447-53. Dunn IS, Jennings PA. PMID: 1518794.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    161. Mutational analysis of protein folding mechanisms. Methods Enzymol. 1991; 202:113-26. Jennings PA, Saalau-Bethell SM, Finn BE, Chen XW, Matthews CR. PMID: 1784172.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    162. Protein modification from mutational analysis of an autologous peptide fragment. Protein Eng. 1990 Dec; 4(2):205-13. Dunn IS, Jennings PA. PMID: 2127459.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    163. Specific gene suppression by engineered ribozymes in monkey cells. Proc Natl Acad Sci U S A. 1989 Dec; 86(23):9139-43. Cameron FH, Jennings PA. PMID: 2556702.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    164. Fimbriae of Bacteroides nodosus: protein engineering of the structural subunit for the production of an exogenous peptide. Protein Eng. 1989 Jan; 2(5):365-9. Jennings PA, Bills MM, Irving DO, Mattick JS. PMID: 2564674.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    165. Nucleic acid flow cytometry in large cell lymphoma. Cancer Res. 1988 Nov 15; 48(22):6614-9. McLaughlin P, Osborne BM, Johnston D, Jennings P, Butler JJ, Cabanillas F, Barlogie B. PMID: 3180071.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    166. Improved peptide function from random mutagenesis over short 'windows'. Protein Eng. 1988 Oct; 2(4):283-91. Dunn IS, Cowan R, Jennings PA. PMID: 3150542.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    167. Inhibition of SV40 replicon function by engineered antisense RNA transcribed by RNA polymerase III. EMBO J. 1987 Oct; 6(10):3043-7. Jennings PA, Molloy PL. PMID: 2446865.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    168. Transplantation of bovine squamous cell carcinoma into congenitally athymic nude mice. Vet Rec. 1977 Nov 05; 101(19):384-5. Hoffmann D, Jennings PA, Spradbrow PB. PMID: 595272.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
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