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    David Karow

    TitleAssociate Clinical Professor
    SchoolUniversity of California, San Diego
    DepartmentRadiology
    Address9500 Gilman Drive #0841
    CA La Jolla 92093
    Phone858-534-8447
    vCardDownload vCard

      Collapse Biography 
      Collapse Education and Training
      University of California, Los AngelesFellowship2012Abdominal Imaging
      University of California, San DiegoResidency2011Diagnostic Radiology
      University of California, IrvineInternship2006Internal Medicine
      University of MichiganM.D./Ph.D.2005Medicine
      University of MichiganB.S1994Cellular and Molecular Biology
      Collapse Awards and Honors
      University of California, San Diego Department of Radiology2014Excellence in Clinical Innovation Award
      University of California, San Diego Department of Radiology Alumni Association2011Elliott C. Lasser Award for Excellence in Research
      Radiology2010Original research selected as the cover for the September 2010 issue
      American Roentgen Ray Society2009Executive Council Award
      Radiology Society of North America2008RSNA Trainee Research Prize
      University of California, Irvine, Department of Internal Medicine2005Letter of Commendation
      University of Michigan Medical School2005Recipient of the Dean’s Award for Research Excellence
      University of Michigan Medical School, Medical Scientist Training Program2005Recipient of the MSTP (M.D./Ph.D.) Excellence in Research Award
      University of Michigan Medical School2005Selected to graduate with Distinction in Research
      Nominated by Dr. Jonathan Gleadle, Ph.D., of the Wellcome Trust Centre for Human Genetics2004Gray, Karow et al. Nature publication was selected by Faculty 1000 as an important recent pub.
      National Institutes of Health1997  - 2005MSTP Training Grant NIGMS T32 GM07863
      University of Michigan1994Order of Omega Scholarship, Leadership and Service Award Recipient
      Kilmer Scholarship1990  - 1994Undergraduate students pursuing medical careers scholarship recipient

      Collapse ORNG Applications 
      Collapse Websites

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Desikan RS, Fan CC, Wang Y, Schork AJ, Cabral HJ, Cupples LA, Thompson WK, Besser L, Kukull WA, Holland D, Chen CH, Brewer JB, Karow D, Kauppi K, Witoelar A, Karch CM, Bonham LW, Yokoyama JS, Rosen HJ, Miller BL, Dillon WP, Wilson DM, Hess CP, Pericak-Vance M, Haines JL, Farrer LA, Mayeux R, Hardy J, Goate AM, Hyman BT, Schellenberg GD, McEvoy LK, Andreassen OA, Dale AM. Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score. PLoS Med. 2017 Mar; 14(3):e1002258. PMID: 28323831.
        View in: PubMed
      2. Brunsing RL, Schenker-Ahmed NM, White NS, Parsons JK, Kane C, Kuperman J, Bartsch H, Kader AK, Rakow-Penner R, Seibert TM, Margolis D, Raman SS, McDonald CR, Farid N, Kesari S, Hansel D, Shabaik A, Dale AM, Karow D. Restriction spectrum imaging: An evolving imaging biomarker in prostate MRI. J Magn Reson Imaging. 2016 Aug 16. PMID: 27527500.
        View in: PubMed
      3. Yamin G, Schenker-Ahmed NM, Shabaik A, Adams D, Bartsch H, Kuperman J, White NS, Rakow-Penner RA, McCammack K, Parsons JK, Kane CJ, Dale AM, Karow D. Voxel Level Radiologic-Pathologic Validation of Restriction Spectrum Imaging Cellularity Index with Gleason Grade in Prostate Cancer. Clin Cancer Res. 2016 Jun 1; 22(11):2668-74. PMID: 27250935.
        View in: PubMed
      4. McCammack KC, Schenker-Ahmed NM, White NS, Best SR, Marks RM, Heimbigner J, Kane CJ, Parsons JK, Kuperman JM, Bartsch H, Desikan RS, Rakow-Penner RA, Liss MA, Margolis DJ, Raman SS, Shabaik A, Dale AM, Karow D. Restriction spectrum imaging improves MRI-based prostate cancer detection. Abdom Radiol (NY). 2016 May; 41(5):946-53. PMID: 26910114.
        View in: PubMed
      5. McCammack KC, Kane CJ, Parsons JK, White NS, Schenker-Ahmed NM, Kuperman JM, Bartsch H, Desikan RS, Rakow-Penner RA, Adams D, Liss MA, Mattrey RF, Bradley WG, Margolis DJ, Raman SS, Shabaik A, Dale AM, Karow D. In vivo prostate cancer detection and grading using restriction spectrum imaging-MRI. Prostate Cancer Prostatic Dis. 2016 Jun; 19(2):168-73. PMID: 26754261.
        View in: PubMed
      6. Liss MA, DeConde R, Caovan D, Hofler J, Gabe M, Palazzi KL, Patel ND, Lee HJ, Ideker T, Van Poppel H, Karow D, Aertsen M, Casola G, Derweesh IH. Parenchymal Volumetric Assessment as a Predictive Tool to Determine Renal Function Benefit of Nephron-Sparing Surgery Compared with Radical Nephrectomy. J Endourol. 2016 Jan; 30(1):114-21. PMID: 26192380.
        View in: PubMed
      7. Desikan RS, Schork AJ, Wang Y, Thompson WK, Dehghan A, Ridker PM, Chasman DI, McEvoy LK, Holland D, Chen CH, Karow D, Brewer JB, Hess CP, Williams J, Sims R, O'Donovan MC, Choi SH, Bis JC, Ikram MA, Gudnason V, DeStefano AL, van der Lee SJ, Psaty BM, van Duijn CM, Launer L, Seshadri S, Pericak-Vance MA, Mayeux R, Haines JL, Farrer LA, Hardy J, Ulstein ID, Aarsland D, Fladby T, White LR, Sando SB, Rongve A, Witoelar A, Djurovic S, Hyman BT, Snaedal J, Steinberg S, Stefansson H, Stefansson K, Schellenberg GD, Andreassen OA, Dale AM. Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease. Circulation. 2015 Jun 9; 131(23):2061-9. PMID: 25862742.
        View in: PubMed
      8. Liss MA, White NS, Parsons JK, Schenker-Ahmed NM, Rakow-Penner R, Kuperman JM, Bartsch H, Choi HW, Mattrey RF, Bradley WG, Shabaik A, Huang J, Margolis DJ, Raman SS, Marks LS, Kane CJ, Reiter RE, Dale AM, Karow D. MRI-Derived Restriction Spectrum Imaging Cellularity Index is Associated with High Grade Prostate Cancer on Radical Prostatectomy Specimens. Front Oncol. 2015; 5:30. PMID: 25741473.
        View in: PubMed
      9. Rakow-Penner RA, White NS, Parsons JK, Choi HW, Liss MA, Kuperman JM, Schenker-Ahmed N, Bartsch H, Mattrey RF, Bradley WG, Shabaik A, Huang J, Margolis DJ, Raman SS, Marks L, Kane CJ, Reiter RE, Karow D, Dale AM. Novel technique for characterizing prostate cancer utilizing MRI restriction spectrum imaging: proof of principle and initial clinical experience with extraprostatic extension. Prostate Cancer Prostatic Dis. 2015 Mar; 18(1):81-5. PMID: 25559097.
        View in: PubMed
      10. White NS, McDonald CR, Farid N, Kuperman J, Karow D, Schenker-Ahmed NM, Bartsch H, Rakow-Penner R, Holland D, Shabaik A, Bjørnerud A, Hope T, Hattangadi-Gluth J, Liss M, Parsons JK, Chen CC, Raman S, Margolis D, Reiter RE, Marks L, Kesari S, Mundt AJ, Kaine CJ, Carter BS, Bradley WG, Dale AM. Diffusion-Weighted Imaging in Cancer: Physical Foundations and Applications of Restriction Spectrum Imaging. Cancer Res. 2014 Sep 1; 74(17):4638-4652. PMID: 25183788.
        View in: PubMed
      11. Karow D, McEvoy LK, Fennema-Notestine C, Hagler DJ, Jennings RG, Brewer JB, Hoh CK, Dale AM. Relative capability of MR imaging and FDG PET to depict changes associated with prodromal and early Alzheimer disease. Radiology. 2010 Sep; 256(3):932-42. PMID: 20720076.
        View in: PubMed
      12. Walhovd KB, Fjell AM, Brewer J, McEvoy LK, Fennema-Notestine C, Hagler DJ, Jennings RG, Karow D, Dale AM. Combining MR imaging, positron-emission tomography, and CSF biomarkers in the diagnosis and prognosis of Alzheimer disease. AJNR Am J Neuroradiol. 2010 Feb; 31(2):347-54. PMID: 20075088.
        View in: PubMed
      13. Fennema-Notestine C, Hagler DJ, McEvoy LK, Fleisher AS, Wu EH, Karow D, Dale AM. Structural MRI biomarkers for preclinical and mild Alzheimer's disease. Hum Brain Mapp. 2009 Oct; 30(10):3238-53. PMID: 19277975.
        View in: PubMed
      14. Zimmer M, Gray JM, Pokala N, Chang AJ, Karow D, Marletta MA, Hudson ML, Morton DB, Chronis N, Bargmann CI. Neurons detect increases and decreases in oxygen levels using distinct guanylate cyclases. Neuron. 2009 Mar 26; 61(6):865-79. PMID: 19323996.
        View in: PubMed
      15. McEvoy LK, Fennema-Notestine C, Roddey JC, Hagler DJ, Holland D, Karow D, Pung CJ, Brewer JB, Dale AM. Alzheimer disease: quantitative structural neuroimaging for detection and prediction of clinical and structural changes in mild cognitive impairment. Radiology. 2009 Apr; 251(1):195-205. PMID: 19201945.
        View in: PubMed
      16. Walhovd KB, Fjell AM, Dale AM, McEvoy LK, Brewer J, Karow D, Salmon DP, Fennema-Notestine C. Multi-modal imaging predicts memory performance in normal aging and cognitive decline. Neurobiol Aging. 2010 Jul; 31(7):1107-21. PMID: 18838195.
        View in: PubMed
      17. Chang AJ, Chronis N, Karow D, Marletta MA, Bargmann CI. A distributed chemosensory circuit for oxygen preference in C. elegans. PLoS Biol. 2006 Sep; 4(9):e274. PMID: 16903785.
        View in: PubMed
      18. Boon EM, Davis JH, Tran R, Karow D, Huang SH, Pan D, Miazgowicz MM, Mathies RA, Marletta MA. Nitric oxide binding to prokaryotic homologs of the soluble guanylate cyclase beta1 H-NOX domain. J Biol Chem. 2006 Aug 4; 281(31):21892-902. PMID: 16728401.
        View in: PubMed
      19. Karow D, Pan D, Davis JH, Behrends S, Mathies RA, Marletta MA. Characterization of functional heme domains from soluble guanylate cyclase. Biochemistry. 2005 Dec 13; 44(49):16266-74. PMID: 16331987.
        View in: PubMed
      20. Pellicena P, Karow D, Boon EM, Marletta MA, Kuriyan J. Crystal structure of an oxygen-binding heme domain related to soluble guanylate cyclases. Proc Natl Acad Sci U S A. 2004 Aug 31; 101(35):12854-9. PMID: 15326296.
        View in: PubMed
      21. Karow D, Pan D, Tran R, Pellicena P, Presley A, Mathies RA, Marletta MA. Spectroscopic characterization of the soluble guanylate cyclase-like heme domains from Vibrio cholerae and Thermoanaerobacter tengcongensis. Biochemistry. 2004 Aug 10; 43(31):10203-11. PMID: 15287748.
        View in: PubMed
      22. Gray JM, Karow D, Lu H, Chang AJ, Chang JS, Ellis RE, Marletta MA, Bargmann CI. Oxygen sensation and social feeding mediated by a C. elegans guanylate cyclase homologue. Nature. 2004 Jul 15; 430(6997):317-22. PMID: 15220933.
        View in: PubMed
      23. Ahuja D, Karow D, Kilpatrick JE, Imperiale MJ. RNA polymerase II-dependent positional effects on mRNA 3' end processing in the adenovirus major late transcription unit. J Biol Chem. 2001 Nov 9; 276(45):41825-31. PMID: 11551915.
        View in: PubMed
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