Emilie Reas

Title(s)Assistant Professor In Residence, Neurosciences
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
ORCID ORCID Icon0000-0002-4110-5154 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of California, Berkeley, Berkeley, CABA12/2004Cognitive Science
    University of California, San Diego, La Jolla, CAPhD03/2014Neurosciences
    Collapse Awards and Honors
    Warren Alpert Foundation2019  - 2022Warren Alpert Distinguished Scholars Fellowship
    UCSD Alzheimer’s Disease Research Center2019  - 2021ADRC Research Education Program Fellowship
    American Federation for Aging Research2019  - 2019Postdoctoral Transition Award in Aging
    BrightFocus2016  - 2018Alzheimer’s Disease Research Grant
    UCSD Alzheimer’s Disease Research Center2014  - 2015New Investigator Research Grant
    Kavli Institute for Brain and Mind2012  - 2013Innovative Research Grant
    Institute for Neural Computation2012  - 2013NIH Pre-doctoral Fellowship
    UCSD2011  - 2013Chancellor’s Interdisciplinary Collaboratories Fellowship

    Collapse Overview 
    Collapse Websites

    Collapse Research 
    Collapse Research Activities and Funding
    The mediating role of blood-brain barrier dysfunction in effects of systemic inflammation on brain microstructure and memory
    AFAR/McKnight Brain Research Foundation Oct 1, 2022 - Sep 30, 2025
    Role: Principal Investigator
    COVID-19-related blood-brain barrier and microstructural brain injury: Sex differences and synergy with Alzheimer's disease risk
    NIH R01AG077202Sep 16, 2022 - Nov 30, 2027
    Role: Principal Investigator
    Association of blood-brain barrier breakdown with brain microstructure neuropathology in early Alzheimer's Disease
    NIH R00AG057797Sep 1, 2021 - May 31, 2024
    Role: Principal Investigator
    Association of blood-brain barrier breakdown with structural and molecular neuropathology in early Alzheimer's disease
    NIH K99AG057797Sep 1, 2019 - Aug 31, 2021
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Faculty Mentoring

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Effects of APOE2 and APOE4 on brain microstructure in older adults: modification by age, sex, and cognitive status. Alzheimers Res Ther. 2024 01 11; 16(1):7. Reas ET, Triebswetter C, Banks SJ, McEvoy LK. PMID: 38212861; PMCID: PMC10782616.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    2. Improved multimodal prediction of progression from MCI to Alzheimer's disease combining genetics with quantitative brain MRI and cognitive measures. Alzheimers Dement. 2023 11; 19(11):5151-5158. Reas ET, Shadrin A, Frei O, Motazedi E, McEvoy L, Bahrami S, van der Meer D, Makowski C, Loughnan R, Wang X, Broce I, Banks SJ, Fominykh V, Cheng W, Holland D, Smeland OB, Seibert T, Selbaek G, Brewer JB, Fan CC, Andreassen OA, Dale AM, Alzheimer's Disease Neuroimaging Initiative. PMID: 37132098; PMCID: PMC10620101.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    3. Neuroimaging-Derived Predicted Brain Age and Alcohol Use Among Community-Dwelling Older Adults. Am J Geriatr Psychiatry. 2023 09; 31(9):669-678. Funk-White M, Wing D, Eyler LT, Moore AA, Reas ET, McEvoy L. PMID: 36925380.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    4. Midlife omega-3 fatty acid intake predicts later life white matter microstructure in an age- and APOE-dependent manner. Cereb Cortex. 2023 02 20; 33(5):2143-2151. Tsiknia AA, Bergstrom J, Reas ET. PMID: 35584792; PMCID: PMC9977375.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    5. Sleep quality and sleep duration predict brain microstructure among community-dwelling older adults. Neurobiol Aging. 2023 05; 125:90-97. Tsiknia AA, Parada H, Banks SJ, Reas ET. PMID: 36871334; PMCID: PMC10115563.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    6. Sex Differences in the Associations of Obesity with Tau, Amyloid PET, and Cognitive Outcomes in Preclinical Alzheimer's Disease: Cross-Sectional A4 Study. J Alzheimers Dis. 2023; 95(2):615-624. Wang X, Sundermann EE, Buckley RF, Reas ET, McEvoy LK, Banks SJ, A4 Study Team. PMID: 37574737.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Elevated Pure Tone Thresholds Are Associated with Altered Microstructure in Cortical Areas Related to Auditory Processing and Attentional Allocation. J Alzheimers Dis. 2023; 96(3):1163-1172. McEvoy LK, Bergstrom J, Hagler DJ, Wing D, Reas ET. PMID: 37955091; PMCID: PMC10793660.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    8. Pulse pressure trajectories predict brain microstructure in community-dwelling older adults: Associations with executive function and modification by APOE. Alzheimers Dement. 2023 05; 19(5):1963-1973. Parada H, Bergstrom J, Bangen KJ, Reas ET. PMID: 36377803; PMCID: PMC10182213.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    9. Sex differences in Alzheimer's disease: plasma MMP-9 and markers of disease severity. Alzheimers Res Ther. 2022 11 02; 14(1):160. Tsiknia AA, Sundermann EE, Reas ET, Edland SD, Brewer JB, Galasko D, Banks SJ, Alzheimer’s Disease Neuroimaging Initiative. PMID: 36324151; PMCID: PMC9628176.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    10. Associations between MRI-assessed locus coeruleus integrity and cortical gray matter microstructure. Cereb Cortex. 2022 09 19; 32(19):4191-4203. Elman JA, Puckett OK, Hagler DJ, Pearce RC, Fennema-Notestine C, Hatton SN, Lyons MJ, McEvoy LK, Panizzon MS, Reas ET, Dale AM, Franz CE, Kremen WS. PMID: 34969072; PMCID: PMC9528780.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    11. Sex differences in plasma p-tau181 associations with Alzheimer's disease biomarkers, cognitive decline, and clinical progression. Mol Psychiatry. 2022 10; 27(10):4314-4322. Tsiknia AA, Edland SD, Sundermann EE, Reas ET, Brewer JB, Galasko D, Banks SJ, Alzheimer’s Disease Neuroimaging Initiative. PMID: 35768637; PMCID: PMC9718670.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    12. Sex and APOE ɛ4 modify the effect of cardiovascular risk on tau in cognitively normal older adults. Brain Commun. 2022; 4(1):fcac035. Tsiknia AA, Reas E, Bangen KJ, Sundermann EE, McEvoy L, Brewer JB, Edland SD, Banks SJ, Alzheimer’s Disease Neuroimaging Initiative. PMID: 35233525; PMCID: PMC8882003.
      View in: PubMed   Mentions: 5  
    13. Sex differences in Alzheimer's disease: do differences in tau explain the verbal memory gap? Neurobiol Aging. 2021 11; 107:70-77. Banks SJ, Andrews MJ, Digma L, Madsen J, Reas ET, Caldwell JZK, McEvoy LK, Fan CC, Dale AM, Brewer JB, Alzheimer's Disease Neuroimaging Initiative. PMID: 34399127; PMCID: PMC8963683.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    14. Brain microstructure mediates sex-specific patterns of cognitive aging. Aging (Albany NY). 2021 01 28; 13(3):3218-3238. Reas ET, Hagler DJ, Zhong AJ, Lee RR, Dale AM, McEvoy LK. PMID: 33510046; PMCID: PMC7906181.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    15. Age and Sex Differences in the Associations of Pulse Pressure With White Matter and Subcortical Microstructure. Hypertension. 2021 03 03; 77(3):938-947. Reas ET, Laughlin GA, Hagler DJ, Lee RR, Dale AM, McEvoy LK. PMID: 33461315; PMCID: PMC7878422.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    16. Associations between age and brain microstructure in older community-dwelling men and women: the Rancho Bernardo Study. Neurobiol Aging. 2020 11; 95:94-103. Reas ET, Hagler DJ, Andrews MJ, Lee RR, Dale AM, McEvoy LK. PMID: 32768868; PMCID: PMC7609610.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    17. Hearing Impairment and Cognitive Decline in Older, Community-Dwelling Adults. J Gerontol A Biol Sci Med Sci. 2020 02 14; 75(3):567-573. Alattar AA, Bergstrom J, Laughlin GA, Kritz-Silverstein D, Richard EL, Reas ET, Harris JP, Barrett-Connor E, McEvoy LK. PMID: 30753308; PMCID: PMC7328194.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    18. Associations Between Microstructure, Amyloid, and Cognition in Amnestic Mild Cognitive Impairment and Dementia. J Alzheimers Dis. 2020; 73(1):347-357. Reas ET, Hagler DJ, Kuperman JM, Wierenga CE, Galasko D, White NS, Dale AM, Banks SJ, McEvoy LK, Brewer JB. PMID: 31796676; PMCID: PMC7266036.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    19. Tau and atrophy: domain-specific relationships with cognition. Alzheimers Res Ther. 2019 07 27; 11(1):65. Digma LA, Madsen JR, Reas ET, Dale AM, Brewer JB, Banks SJ, Alzheimer’s Disease Neuroimaging Initiative. PMID: 31351484; PMCID: PMC6661099.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    20. Identification of genetic heterogeneity of Alzheimer's disease across age. Neurobiol Aging. 2019 12; 84:243.e1-243.e9. Lo MT, Kauppi K, Fan CC, Sanyal N, Reas ET, Sundar VS, Lee WC, Desikan RS, McEvoy LK, Chen CH, Alzheimer's Disease Genetics Consortium. PMID: 30979435; PMCID: PMC6783343.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    21. Lifetime physical activity and late-life cognitive function: the Rancho Bernardo study. Age Ageing. 2019 03 01; 48(2):241-246. Reas ET, Laughlin GA, Bergstrom J, Kritz-Silverstein D, Richard EL, Barrett-Connor E, McEvoy LK. PMID: 30615048; PMCID: PMC6424376.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    22. Effects of APOE on cognitive aging in community-dwelling older adults. Neuropsychology. 2019 Mar; 33(3):406-416. Reas ET, Laughlin GA, Bergstrom J, Kritz-Silverstein D, Barrett-Connor E, McEvoy LK. PMID: 30730162; PMCID: PMC6513314.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    23. Physical Activity and Trajectories of Cognitive Change in Community-Dwelling Older Adults: The Rancho Bernardo Study. J Alzheimers Dis. 2019; 71(1):109-118. Reas ET, Laughlin GA, Bergstrom J, Kritz-Silverstein D, McEvoy LK. PMID: 31356211; PMCID: PMC7286204.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    24. Microstructural brain changes track cognitive decline in mild cognitive impairment. Neuroimage Clin. 2018; 20:883-891. Reas ET, Hagler DJ, White NS, Kuperman JM, Bartsch H, Wierenga CE, Galasko D, Brewer JB, Dale AM, McEvoy LK. PMID: 30290303; PMCID: PMC6171091.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    25. Dietary Patterns and Cognitive Function among Older Community-Dwelling Adults. Nutrients. 2018 Aug 14; 10(8). Richard EL, Laughlin GA, Kritz-Silverstein D, Reas ET, Barrett-Connor E, McEvoy LK. PMID: 30110945; PMCID: PMC6116163.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    26. Amyloid and Tau Pathology in Normal Cognitive Aging. J Neurosci. 2017 08 09; 37(32):7561-7563. Reas ET. PMID: 28821682; PMCID: PMC6596650.
      View in: PubMed   Mentions: 11     Fields:    
    27. Sensitivity of restriction spectrum imaging to memory and neuropathology in Alzheimer's disease. Alzheimers Res Ther. 2017 Aug 02; 9(1):55. Reas ET, Hagler DJ, White NS, Kuperman JM, Bartsch H, Cross K, Loi RQ, Balachandra AR, Meloy MJ, Wierenga CE, Galasko D, Brewer JB, Dale AM, McEvoy LK. PMID: 28764771; PMCID: PMC5539622.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    28. Effects of Sex and Education on Cognitive Change Over a 27-Year Period in Older Adults: The Rancho Bernardo Study. Am J Geriatr Psychiatry. 2017 Aug; 25(8):889-899. Reas ET, Laughlin GA, Bergstrom J, Kritz-Silverstein D, Barrett-Connor E, McEvoy LK. PMID: 28433548; PMCID: PMC5522346.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    29. Vitamin D Insufficiency and Cognitive Function Trajectories in Older Adults: The Rancho Bernardo Study. J Alzheimers Dis. 2017; 58(3):871-883. Laughlin GA, Kritz-Silverstein D, Bergstrom J, Reas ET, Jassal SK, Barrett-Connor E, McEvoy LK. PMID: 28505973; PMCID: PMC5954988.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    30. Moderate, Regular Alcohol Consumption is Associated with Higher Cognitive Function in Older Community-Dwelling Adults. J Prev Alzheimers Dis. 2016 Sep; 3(2):105-113. Reas ET, Laughlin GA, Kritz-Silverstein D, Barrett-Connor E, McEvoy LK. PMID: 27184039; PMCID: PMC4866612.
      View in: PubMed   Mentions: 20     Fields:    
    31. Mean signal and response time influences on multivoxel signals of contextual retrieval in the medial temporal lobe. Brain Behav. 2015 Feb; 5(2):e00302. Reas ET, Brewer JB. PMID: 25646149; PMCID: PMC4312925.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    32. Animal model of methylphenidate's long-term memory-enhancing effects. Learn Mem. 2014 Jan 16; 21(2):82-9. Carmack SA, Howell KK, Rasaei K, Reas ET, Anagnostaras SG. PMID: 24434869; PMCID: PMC3895222.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    33. Imbalance of incidental encoding across tasks: an explanation for non-memory-related hippocampal activations? J Exp Psychol Gen. 2013 Nov; 142(4):1171-9. Reas ET, Brewer JB. PMID: 23773160; PMCID: PMC3834009.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    34. Effortful retrieval reduces hippocampal activity and impairs incidental encoding. Hippocampus. 2013 May; 23(5):367-79. Reas ET, Brewer JB. PMID: 23378272; PMCID: PMC4049294.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    35. Erratum: search-related suppression of hippocampus and default network activity during associative memory retrieval. Front Hum Neurosci. 2013; 7:2. Reas ET, Gimbel SI, Hales JB, Brewer JB. PMID: 23355818; PMCID: PMC3553375.
      View in: PubMed   Mentions:
    36. Retrieval search and strength evoke dissociable brain activity during episodic memory recall. J Cogn Neurosci. 2013 Feb; 25(2):219-33. Reas ET, Brewer JB. PMID: 23190328; PMCID: PMC4091972.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    37. Search-Related Suppression of Hippocampus and Default Network Activity during Associative Memory Retrieval. Front Hum Neurosci. 2011; 5:112. Reas ET, Gimbel SI, Hales JB, Brewer JB. PMID: 22046159; PMCID: PMC3202230.
      View in: PubMed   Mentions: 16  
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