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    Lucila Ohno-Machado

    Address9500 Gilman Drive #0728
    CA La Jolla 92093
    Phone858-822-4931
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      Collapse Research 
      Collapse Research Activities and Funding
      Decentralized differentially-private methods for dynamic data release and analysis
      NIH/NIGMS R01GM118609Jan 1, 2017 - Dec 31, 2020
      Role: Principal Investigator
      California Precision Medicine Consortium
      NIH OT2OD024611Sep 27, 2016 - Aug 31, 2017
      Role: Principal Investigator
      SERGEANT: SEcuRe GEnome Analysis competition
      NIH/NHGRI R13HG009072Sep 12, 2016 - Jun 30, 2018
      Role: Principal Investigator
      iCONCUR: informed CONsent for Clinical data and biosample Use for Research
      NIH/NHGRI R01HG008802Sep 21, 2015 - Jun 30, 2018
      Role: Principal Investigator
      BioCADDIE: Biomedical and healthCAre Data Discovery and Indexing Engine center
      NIH/NIAID U24AI117966Sep 29, 2014 - Aug 31, 2017
      Role: Principal Investigator
      San Diego Biomedical Informatics Education & Research (SABER)
      NIH/NLM T15LM011271Jul 1, 2012 - Jun 30, 2022
      Role: Principal Investigator
      Phenotype Discovery in NHLBI Genomic Studies (PhD)
      NIH/NHLBI UH3HL108785Jul 19, 2011 - Sep 23, 2014
      Role: Principal Investigator
      Phenotype Discovery in NHLBI Genomic Studies (PhD)
      NIH/NHLBI UH2HL108785Jul 19, 2011 - May 31, 2013
      Role: Principal Investigator
      SCANNER: Scalable National Network for Effectiveness Research
      AHRQ R01HS019913Sep 30, 2010 - Sep 29, 2013
      Role: Principal Investigator
      iDASH: Integrating Data for Analysis, Anonymization, and Sharing
      NIH/NHLBI U54HL108460Sep 20, 2010 - Jun 30, 2016
      Role: Principal Investigator
      Global Health Knowledge Collective: A Collaborative Toolkit for Global Health
      NIH/FIC R24TW008805Sep 15, 2010 - Aug 31, 2012
      Role: Principal Investigator
      Assessing quality of individual predictions in medical decision support systems
      NIH/NLM R01LM009520Jun 1, 2007 - Dec 2, 2011
      Role: Principal Investigator
      Biomedical Research Informatics for Global Health Training (BRIGHT) Program
      NIH/FIC D43TW007015Jun 1, 2004 - Jun 30, 2014
      Role: Principal Investigator
      CONFERENCE--GUIDELINE INTERCHANGE FORMAT (GLIF) WORKSHOP
      NIH/NLM R13LM006929Jan 3, 2000 - Aug 31, 2000
      Role: Principal Investigator
      BRAZIL/USA INTERNATIONAL TRAINING IN MEDICAL INFORMATICS
      NIH/FIC D43TW001279Sep 30, 1999 - May 31, 2004
      Role: Principal Investigator
      COMPONENT BASED TOOLS FOR CONNECTIONIST CLASSIFICATION
      NIH/NLM R01LM006538Sep 30, 1998 - Aug 31, 2001
      Role: Principal Investigator
      COMPONENT BASED TOOLS FOR CONNECTIONIST CLASSIFICATION
      NIH/NLM R29LM006538Sep 30, 1998 - Aug 31, 2000
      Role: Principal Investigator
      COMPONENT BASED TOOLS FOR CONNECTIONIST CLASSIFICATION
      NIH/NLM R55LM006538Sep 15, 1997 - Sep 29, 1998
      Role: Principal Investigator
      CONNECTIONIST MODELS OF SURVIVAL IN HIV INFECTION
      AHRQ R03HS008462Sep 1, 1994 - Feb 29, 1996
      Role: Principal Investigator
      Biomedical Informatics and Data Science Research Training Program (BIRT)
      NIH/NLM T15LM007092Jul 1, 1992 - Jun 30, 2022
      Role: Principal Investigator

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Sansone SA, Gonzalez-Beltran A, Rocca-Serra P, Alter G, Grethe JS, Xu H, Fore IM, Lyle J, Gururaj AE, Chen X, Kim HE, Zong N, Li Y, Liu R, Ozyurt IB, Ohno-Machado L. DATS, the data tag suite to enable discoverability of datasets. Sci Data. 2017 Jun 06; 4:170059. PMID: 28585923.
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      2. Ohno-Machado L, Sansone SA, Alter G, Fore I, Grethe J, Xu H, Gonzalez-Beltran A, Rocca-Serra P, Gururaj AE, Bell E, Soysal E, Zong N, Kim HE. Finding useful data across multiple biomedical data repositories using DataMed. Nat Genet. 2017 May 26; 49(6):816-819. PMID: 28546571.
        View in: PubMed
      3. Ohno-Machado L. Electronic health records: usability and utilization by health care providers and patients. J Am Med Inform Assoc. 2017 Apr 01; 24(e1):e1. PMID: 28395061.
        View in: PubMed
      4. Raisaro JL, Tramèr F, Ji Z, Bu D, Zhao Y, Carey K, Lloyd D, Sofia H, Baker D, Flicek P, Shringarpure S, Bustamante C, Wang S, Jiang X, Ohno-Machado L, Tang H, Wang X, Hubaux JP. Addressing Beacon re-identification attacks: quantification and mitigation of privacy risks. J Am Med Inform Assoc. 2017 Feb 20. PMID: 28339683.
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      5. Sitapati A, Kim H, Berkovich B, Marmor R, Singh S, El-Kareh R, Clay B, Ohno-Machado L. Integrated precision medicine: the role of electronic health records in delivering personalized treatment. Wiley Interdiscip Rev Syst Biol Med. 2017 May; 9(3). PMID: 28207198.
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      6. Kuo TT, Rao P, Maehara C, Doan S, Chaparro JD, Day ME, Farcas C, Ohno-Machado L, Hsu CN. Ensembles of NLP Tools for Data Element Extraction from Clinical Notes. AMIA Annu Symp Proc. 2016; 2016:1880-1889. PMID: 28269947.
        View in: PubMed
      7. Kim J, Shimizu C, Kingsmore SF, Veeraraghavan N, Levy E, Ribeiro Dos Santos AM, Yang H, Flatley J, Hoang LT, Hibberd ML, Tremoulet AH, Harismendy O, Ohno-Machado L, Burns JC. Whole genome sequencing of an African American family highlights toll like receptor 6 variants in Kawasaki disease susceptibility. PLoS One. 2017; 12(2):e0170977. PMID: 28151979.
        View in: PubMed
      8. Chen F, Wang S, Jiang X, Ding S, Lu Y, Kim J, Sahinalp SC, Shimizu C, Burns JC, Wright VJ, Png E, Hibberd ML, Lloyd DD, Yang H, Telenti A, Bloss CS, Fox D, Lauter K, Ohno-Machado L. PRINCESS: Privacy-protecting Rare disease International Network Collaboration via Encryption through Software guard extensionS. Bioinformatics. 2017 Jan 08. PMID: 28065902.
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      9. Ohno-Machado L. Using health information technology for clinical decision support and predictive analytics. J Am Med Inform Assoc. 2017 Jan; 24(1):1. PMID: 28039394.
        View in: PubMed
      10. Ohno-Machado L. Data-driven informatics tools targeting patients and providers. J Am Med Inform Assoc. 2016 Nov; 23(6):1039. PMID: 27880716.
        View in: PubMed
      11. Tang H, Jiang X, Wang X, Wang S, Sofia H, Fox D, Lauter K, Malin B, Telenti A, Xiong L, Ohno-Machado L. Protecting genomic data analytics in the cloud: state of the art and opportunities. BMC Med Genomics. 2016 Oct 13; 9(1):63. PMID: 27733153.
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      12. Nodora JN, Komenaka IK, Bouton ME, Ohno-Machado L, Schwab R, Kim HE, Farcas C, Perez G, Elena Martinez M. Biospecimen Sharing Among Hispanic Women in a Safety-Net Clinic: Implications for the Precision Medicine Initiative. J Natl Cancer Inst. 2017 Feb; 109(2). PMID: 27688295.
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      13. Eguchi A, Lazaro RG, Wang J, Kim J, Povero D, Willliams B, Ho SB, Stärkel P, Schnabl B, Ohno-Machado L, Tsukamoto H, Feldstein AE. Extracellular vesicles released by hepatocytes from gastric infusion model of ALD contain a miRNA barcode that can be detected in blood. Hepatology. 2016 Sep 17. PMID: 27639178.
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      14. Kim H, Bell E, Kim J, Sitapati A, Ramsdell J, Farcas C, Friedman D, Feupe SF, Ohno-Machado L. iCONCUR: informed consent for clinical data and bio-sample use for research. J Am Med Inform Assoc. 2016 Sep 02. PMID: 27589942.
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      15. Ohno-Machado L. Building systems that change clinical practice and advance health sciences research. J Am Med Inform Assoc. 2016 Sep; 23(5):857. PMID: 27562746.
        View in: PubMed
      16. Shi H, Jiang C, Dai W, Jiang X, Tang Y, Ohno-Machado L, Wang S. Secure Multi-pArty Computation Grid LOgistic REgression (SMAC-GLORE). BMC Med Inform Decis Mak. 2016; 16 Suppl 3:89. PMID: 27454168.
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      17. Wei W, Marmor R, Singh S, Wang S, Demner-Fushman D, Kuo TT, Hsu CN, Ohno-Machado L. Finding Related Publications: Extending the Set of Terms Used to Assess Article Similarity. AMIA Jt Summits Transl Sci Proc. 2016; 2016:225-34. PMID: 27570676; PMCID: PMC5001748.
      18. Doan S, Maehara CK, Chaparro JD, Lu S, Liu R, Graham A, Berry E, Hsu CN, Kanegaye JT, Lloyd DD, Ohno-Machado L, Burns JC, Tremoulet AH. Building a Natural Language Processing Tool to Identify Patients With High Clinical Suspicion for Kawasaki Disease from Emergency Department Notes. Acad Emerg Med. 2016 May; 23(5):628-36. PMID: 26826020.
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      19. Ohno-Machado L. Data and the clinical decision support loop. J Am Med Inform Assoc. 2016 Apr; 23(e1):e1. PMID: 27071919.
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      20. Ohno-Machado L. A message to the next generation of biomedical informatics professionals. J Am Med Inform Assoc. 2016 Mar; 23(2):241. PMID: 26961493.
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      21. Ohno-Machado L. Using informatics to engage patients and healthcare providers. J Am Med Inform Assoc. 2016 Jan; 23(1):1. PMID: 26912536.
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      22. Kroll JE, Kim J, Ohno-Machado L, de Souza SJ. Splicing Express: a software suite for alternative splicing analysis using next-generation sequencing data. PeerJ. 2015; 3:e1419. PMID: 26618088.
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      23. Li Y, Jiang X, Wang S, Xiong H, Ohno-Machado L. VERTIcal Grid lOgistic regression (VERTIGO). J Am Med Inform Assoc. 2016 May; 23(3):570-9. PMID: 26554428.
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      24. Han D, Wang S, Jiang C, Jiang X, Kim HE, Sun J, Ohno-Machado L. Trends in biomedical informatics: automated topic analysis of JAMIA articles. J Am Med Inform Assoc. 2015 Nov; 22(6):1153-63. PMID: 26555018.
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      25. Ohno-Machado L. Mining electronic health record data: finding the gold nuggets. J Am Med Inform Assoc. 2015 Sep; 22(5):937. PMID: 26330468.
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      26. Lu CL, Wang S, Ji Z, Wu Y, Xiong L, Jiang X, Ohno-Machado L. WebDISCO: a web service for distributed cox model learning without patient-level data sharing. J Am Med Inform Assoc. 2015 Nov; 22(6):1212-9. PMID: 26159465.
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      27. Meeker D, Jiang X, Matheny ME, Farcas C, D'Arcy M, Pearlman L, Nookala L, Day ME, Kim KK, Kim H, Boxwala A, El-Kareh R, Kuo GM, Resnic FS, Kesselman C, Ohno-Machado L. A system to build distributed multivariate models and manage disparate data sharing policies: implementation in the scalable national network for effectiveness research. J Am Med Inform Assoc. 2015 Nov; 22(6):1187-95. PMID: 26142423.
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      28. Ohno-Machado L. Tailoring informatics interventions to patients and healthcare providers. J Am Med Inform Assoc. 2015 Jul; 22(4):747. PMID: 26116707.
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      29. Ohno-Machado L. A journal's role in resource sharing and reproducibility. J Am Med Inform Assoc. 2015 May; 22(3):491. PMID: 26048962.
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      30. Kim KK, Joseph JG, Ohno-Machado L. Comparison of consumers' views on electronic data sharing for healthcare and research. J Am Med Inform Assoc. 2015 Jul; 22(4):821-30. PMID: 25829461.
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      31. Wei W, Demner-Fushman D, Wang S, Jiang X, Ohno-Machado L. Ranking Medical Subject Headings using a factor graph model. AMIA Jt Summits Transl Sci Proc. 2015; 2015:56-63. PMID: 26306236.
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      32. Wu Y, Jiang X, Wang S, Jiang W, Li P, Ohno-Machado L. Grid multi-category response logistic models. BMC Med Inform Decis Mak. 2015; 15(1):10. PMID: 25886151.
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      33. Jiang X, Wu Y, Marsolo K, Ohno-Machado L. Development of a web service for analysis in a distributed network. EGEMS (Wash DC). 2014; 2(1):1053. PMID: 25848586.
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      34. Jiang X, Zhao Y, Wang X, Malin B, Wang S, Ohno-Machado L, Tang H. A community assessment of privacy preserving techniques for human genomes. BMC Med Inform Decis Mak. 2014 Dec 8; 14 Suppl 1:S1. PMID: 25521230.
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      35. Kim H, Ohno-Machado L, Oh J, Jiang X. Trends in publication of nursing informatics research. AMIA Annu Symp Proc. 2014; 2014:805-14. PMID: 25954387.
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      36. Bell EA, Ohno-Machado L, Grando MA. Sharing my health data: a survey of data sharing preferences of healthy individuals. AMIA Annu Symp Proc. 2014; 2014:1699-708. PMID: 25954442.
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      37. Ohno-Machado L. Focusing on the patient: mHealth, social media, electronic health records, and decision support systems. J Am Med Inform Assoc. 2014 Nov; 21(6):953. PMID: 25301806.
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      38. Ohno-Machado L. Disseminating informatics knowledge and training the next generation of leaders. J Am Med Inform Assoc. 2014 Nov; 21(6):954-6. PMID: 25301807.
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      39. Zhao Y, Wang X, Jiang X, Ohno-Machado L, Tang H. Choosing blindly but wisely: differentially private solicitation of DNA datasets for disease marker discovery. J Am Med Inform Assoc. 2015 Jan; 22(1):100-8. PMID: 25352565.
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      40. Stepanowsky P, Levy E, Kim J, Jiang X, Ohno-Machado L. Prediction of MicroRNA Precursors Using Parsimonious Feature Sets. Cancer Inform. 2014; 13(Suppl 1):95-102. PMID: 25392687.
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      41. Ohno-Machado L. Structuring text and standardizing data for clinical and population health applications. J Am Med Inform Assoc. 2014 Sep; 21(5):763. PMID: 25117592.
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      42. Ross MK, Wei W, Ohno-Machado L. "Big data" and the electronic health record. Yearb Med Inform. 2014; 9(1):97-104. PMID: 25123728.
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      43. Bates DW, Saria S, Ohno-Machado L, Shah A, Escobar G. Big data in health care: using analytics to identify and manage high-risk and high-cost patients. Health Aff (Millwood). 2014 Jul 1; 33(7):1123-31. PMID: 25006137.
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      44. Ohno-Machado L. Networking the country to promote health and scientific discovery. J Am Med Inform Assoc. 2014 Jul; 21(4):575. PMID: 24908676.
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      45. Li H, Xiong L, Ohno-Machado L, Jiang X. Privacy Preserving RBF Kernel Support Vector Machine. Biomed Res Int. 2014; 2014:827371. PMID: 25013805.
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      46. Kim J, Levy E, Ferbrache A, Stepanowsky P, Farcas C, Wang S, Brunner S, Bath T, Wu Y, Ohno-Machado L. MAGI: a Node.js web service for fast microRNA-Seq analysis in a GPU infrastructure. Bioinformatics. 2014 Oct; 30(19):2826-7. PMID: 24907367.
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      47. Ji Z, Jiang X, Wang S, Xiong L, Ohno-Machado L. Differentially private distributed logistic regression using private and public data. BMC Med Genomics. 2014; 7 Suppl 1:S14. PMID: 25079786.
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      48. Wang S, Kim J, Jiang X, Brunner SF, Ohno-Machado L. GAMUT: GPU accelerated microRNA analysis to uncover target genes through CUDA-miRanda. BMC Med Genomics. 2014; 7 Suppl 1:S9. PMID: 25077821.
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      49. Ohno-Machado L, Agha Z, Bell DS, Dahm L, Day ME, Doctor JN, Gabriel D, Kahlon MK, Kim KK, Hogarth M, Matheny ME, Meeker D, Nebeker JR. pSCANNER: patient-centered Scalable National Network for Effectiveness Research. J Am Med Inform Assoc. 2014 Jul; 21(4):621-6. PMID: 24780722.
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      50. Menon AK, Jiang X, Kim J, Vaidya J, Ohno-Machado L. Detecting Inappropriate Access to Electronic Health Records Using Collaborative Filtering. Mach Learn. 2014 Apr 1; 95(1):87-101. PMID: 24683293.
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      51. Ohno-Machado L. NIH's Big Data to Knowledge initiative and the advancement of biomedical informatics. J Am Med Inform Assoc. 2014 Mar 1; 21(2):193. PMID: 24509598.
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      52. Ohno-Machado L. Electronic health record systems: risks and benefits. J Am Med Inform Assoc. 2014 Feb; 21(e1):e1. PMID: 24453123.
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      53. Doan S, Conway M, Phuong TM, Ohno-Machado L. Natural language processing in biomedicine: a unified system architecture overview. Methods Mol Biol. 2014; 1168:275-94. PMID: 24870142.
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      54. Ohno-Machado L. The role of scientific publication in times of change. J Am Med Inform Assoc. 2014 Jan 1; 21(1):1. PMID: 24335250.
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      55. Li P, Jiang X, Wang S, Kim J, Xiong H, Ohno-Machado L. HUGO: Hierarchical mUlti-reference Genome cOmpression for aligned reads. J Am Med Inform Assoc. 2014 Mar 1; 21(2):363-73. PMID: 24368726.
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      56. Kim KK, Browe DK, Logan HC, Holm R, Hack L, Ohno-Machado L. Data governance requirements for distributed clinical research networks: triangulating perspectives of diverse stakeholders. J Am Med Inform Assoc. 2014 Jul; 21(4):714-9. PMID: 24302285.
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      57. Ohno-Machado L. Game changer: how informatics moved from a supporting role to a central position in healthcare. J Am Med Inform Assoc. 2013 Dec; 20(e2):e197. PMID: 24302668.
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      58. Li P, Wang S, Kim J, Xiong H, Ohno-Machado L, Jiang X. DNA-COMPACT: DNA COMpression Based on a Pattern-Aware Contextual Modeling Technique. PLoS One. 2013; 8(11):e80377. PMID: 24282536.
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      59. Jiang X, Tse K, Wang S, Doan S, Kim H, Ohno-Machado L. Recent trends in biomedical informatics: a study based on JAMIA articles. J Am Med Inform Assoc. 2013 Dec; 20(e2):e198-205. PMID: 24214018.
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      60. Ohno-Machado L. Data science and informatics: when it comes to biomedical data, is there a real distinction? J Am Med Inform Assoc. 2013 Nov-Dec; 20(6):1009. PMID: 24114329.
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      61. Jiang W, Li P, Wang S, Wu Y, Xue M, Ohno-Machado L, Jiang X. WebGLORE: a Web service for Grid LOgistic REgression. Bioinformatics. 2013 Dec 15; 29(24):3238-40. PMID: 24072732.
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      62. Ohno-Machado L, Nadkarni P, Johnson K. Natural language processing: algorithms and tools to extract computable information from EHRs and from the biomedical literature. J Am Med Inform Assoc. 2013 Sep-Oct; 20(5):805. PMID: 23935077.
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      63. Doan S, Lin KW, Conway M, Ohno-Machado L, Hsieh A, Feupe SF, Garland A, Ross MK, Jiang X, Farzaneh S, Walker R, Alipanah N, Zhang J, Xu H, Kim HE. PhenDisco: phenotype discovery system for the database of genotypes and phenotypes. J Am Med Inform Assoc. 2014 Jan 1; 21(1):31-6. PMID: 23989082.
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      64. Jiang X, Sarwate AD, Ohno-Machado L. Privacy technology to support data sharing for comparative effectiveness research: a systematic review. Med Care. 2013 Aug; 51(8 Suppl 3):S58-65. PMID: 23774511.
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      65. Butte AJ, Ohno-Machado L. Making it personal: translational bioinformatics. J Am Med Inform Assoc. 2013 Jul-Aug; 20(4):595-6. PMID: 23757438.
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      66. Ohno-Machado L. Electronic health records: monitoring the return on large investments. J Am Med Inform Assoc. 2013 Jun; 20(e1):e1. PMID: 23687172.
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      67. Wang S, Jiang X, Wu Y, Cui L, Cheng S, Ohno-Machado L. EXpectation Propagation LOgistic REgRession (EXPLORER): distributed privacy-preserving online model learning. J Biomed Inform. 2013 Jun; 46(3):480-96. PMID: 23562651.
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      68. Jiang X, Ji Z, Wang S, Mohammed N, Cheng S, Ohno-Machado L. Differential-Private Data Publishing Through Component Analysis. Trans Data Priv. 2013 Apr; 6(1):19-34. PMID: 24409205.
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      69. Dai W, Xiong H, Jiang X, Ohno-Machado L. An Adaptive Difference Distribution-based Coding with Hierarchical Tree Structure for DNA Sequence Compression. Proc Data Compress Conf. 2013; 2013:371-380. PMID: 26501129.
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      70. Vaidya J, Shafiq B, Jiang X, Ohno-Machado L. Identifying inference attacks against healthcare data repositories. AMIA Summits Transl Sci Proc. 2013; 2013:262-6. PMID: 24303279.
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      71. Ohno-Machado L, Farcas C, Kim J, Wang S, Jiang X. Genomes in the cloud: balancing privacy rights and the public good. AMIA Summits Transl Sci Proc. 2013; 2013:128. PMID: 24303320.
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      72. Shimizu C, Kim J, Stepanowsky P, Trinh C, Lau HD, Akers JC, Chen C, Kanegaye JT, Tremoulet A, Ohno-Machado L, Burns JC. Differential expression of miR-145 in children with Kawasaki disease. PLoS One. 2013; 8(3):e58159. PMID: 23483985.
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      73. Ohno-Machado L. Informatics that works for you. J Am Med Inform Assoc. 2013 Mar-Apr; 20(2):211. PMID: 23400397.
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      74. Thawait SK, Kim J, Klufas RA, Morrison WB, Flanders AE, Carrino JA, Ohno-Machado L. Comparison of four prediction models to discriminate benign from malignant vertebral compression fractures according to MRI feature analysis. AJR Am J Roentgenol. 2013 Mar; 200(3):493-502. PMID: 23436836.
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      75. Ohno-Machado L. Sharing data for the public good and protecting individual privacy: informatics solutions to combine different goals. J Am Med Inform Assoc. 2013 Jan 1; 20(1):1. PMID: 23243087.
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      76. Roozgard A, Barzigar N, Wang S, Jiang X, Ohno-Machado L, Cheng S. Nucleotide sequence alignment using sparse coding and belief propagation. Conf Proc IEEE Eng Med Biol Soc. 2013; 2013:588-91. PMID: 24109755.
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      77. Bafna V, Kozanitis C, Deutsch A, Ohno-Machado L, Heiberg A, Varghese G. Abstractions for Genomics. Commun ACM. 2013 Jan; 56(1):83-93. PMID: 25284821.
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      78. Ohno-Machado L. To share or not to share: that is not the question. Sci Transl Med. 2012 Dec 19; 4(165):165cm15. PMID: 23253606.
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      79. Mohammed N, Jiang X, Chen R, Fung BC, Ohno-Machado L. Privacy-preserving heterogeneous health data sharing. J Am Med Inform Assoc. 2013 May 1; 20(3):462-9. PMID: 23242630.
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      80. Jiang X, Menon A, Wang S, Kim J, Ohno-Machado L. Doubly Optimized Calibrated Support Vector Machine (DOC-SVM): an algorithm for joint optimization of discrimination and calibration. PLoS One. 2012; 7(11):e48823. PMID: 23139819.
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      81. Jiang X, Kim J, Wu Y, Wang S, Ohno-Machado L. Selecting cases for whom additional tests can improve prognostication. AMIA Annu Symp Proc. 2012; 2012:1260-8. PMID: 23304404.
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      82. Que J, Jiang X, Ohno-Machado L. A collaborative framework for Distributed Privacy-Preserving Support Vector Machine learning. AMIA Annu Symp Proc. 2012; 2012:1350-9. PMID: 23304414.
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      83. Wu Y, Jiang X, Ohno-Machado L. Preserving Institutional Privacy in Distributed binary Logistic Regression. AMIA Annu Symp Proc. 2012; 2012:1450-8. PMID: 23304425.
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      84. Ohno-Machado L. Careers in informatics: a diversity of options with an abundance of jobs. J Am Med Inform Assoc. 2012 Nov-Dec; 19(6):919. PMID: 23077280.
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      85. Gardner J, Xiong L, Xiao Y, Gao J, Post AR, Jiang X, Ohno-Machado L. SHARE: system design and case studies for statistical health information release. J Am Med Inform Assoc. 2013 Jan 1; 20(1):109-16. PMID: 23059729.
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      86. Ohno-Machado L. Informatics 2.0: implications of social media, mobile health, and patient-reported outcomes for healthcare and individual privacy. J Am Med Inform Assoc. 2012 Sep-Oct; 19(5):683. PMID: 22879365.
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      87. von Muhlen M, Ohno-Machado L. Reviewing social media use by clinicians. J Am Med Inform Assoc. 2012 Sep-Oct; 19(5):777-81. PMID: 22759618.
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      88. Kim H, Tamayo D, Muhkin M, Kim J, Lam J, Ohno-Machado L, Aronoff-Spencer E. Pictogram evaluation and authoring collaboration environment. Nurs Inform. 2012; 2012:214. PMID: 24199088.
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      89. Ohno-Machado L. Big science, big data, and a big role for biomedical informatics. J Am Med Inform Assoc. 2012 Jun; 19(e1):e1. PMID: 22718034.
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      90. Sarin P, Urman RD, Ohno-Machado L. An improved model for predicting postoperative nausea and vomiting in ambulatory surgery patients using physician-modifiable risk factors. J Am Med Inform Assoc. 2012 Nov-Dec; 19(6):995-1002. PMID: 22582204.
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      91. Wu Y, Jiang X, Kim J, Ohno-Machado L. Grid Binary LOgistic REgression (GLORE): building shared models without sharing data. J Am Med Inform Assoc. 2012 Sep-Oct; 19(5):758-64. PMID: 22511014.
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      92. Jiang X, Boxwala AA, El-Kareh R, Kim J, Ohno-Machado L. A patient-driven adaptive prediction technique to improve personalized risk estimation for clinical decision support. J Am Med Inform Assoc. 2012 Jun; 19(e1):e137-44. PMID: 22493049.
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      93. Wu Y, Jiang X, Kim J, Ohno-Machado L. I-spline Smoothing for Calibrating Predictive Models. AMIA Summits Transl Sci Proc. 2012; 2012:39-46. PMID: 22779048.
        View in: PubMed
      94. Ohno-Machado L. Informatics research to enable clinically relevant, personalized genomic medicine. J Am Med Inform Assoc. 2012 Mar-Apr; 19(2):149-50. PMID: 22319175.
        View in: PubMed
      95. Ohno-Machado L. Computer-based safety surveillance and patient-centered health records. J Am Med Inform Assoc. 2012 Jan-Feb; 19(1):1. PMID: 22155973.
        View in: PubMed
      96. Menon AK, Jiang XJ, Vembu S, Elkan C, Ohno-Machado L. Predicting accurate probabilities with a ranking loss. Proc Int Conf Mach Learn. 2012; 2012:703-710. PMID: 25285328.
        View in: PubMed
      97. Ohno-Machado L. Innovative approaches to support patient decision making, improve safety, and enable large-scale clinical research. J Am Med Inform Assoc. 2011 Dec; 18 Suppl 1:i1. PMID: 22180872.
        View in: PubMed
      98. Kim HE, Jiang X, Kim J, Ohno-Machado L. Trends in biomedical informatics: most cited topics from recent years. J Am Med Inform Assoc. 2011 Dec; 18 Suppl 1:i166-70. PMID: 22180873.
        View in: PubMed
      99. Ohno-Machado L, Bafna V, Boxwala AA, Chapman BE, Chapman WW, Chaudhuri K, Day ME, Farcas C, Heintzman ND, Jiang X, Kim H, Kim J, Matheny ME, Resnic FS, Vinterbo SA. iDASH: integrating data for analysis, anonymization, and sharing. J Am Med Inform Assoc. 2012 Mar-Apr; 19(2):196-201. PMID: 22081224.
        View in: PubMed
      100. Jiang X, El-Kareh R, Ohno-Machado L. Improving predictions in imbalanced data using Pairwise Expanded Logistic Regression. AMIA Annu Symp Proc. 2011; 2011:625-34. PMID: 22195118.
        View in: PubMed
      101. Kim J, Grillo JM, Boxwala AA, Jiang X, Mandelbaum RB, Patel BA, Mikels D, Vinterbo SA, Ohno-Machado L. Anomaly and signature filtering improve classifier performance for detection of suspicious access to EHRs. AMIA Annu Symp Proc. 2011; 2011:723-31. PMID: 22195129.
        View in: PubMed
      102. Jiang X, Osl M, Kim J, Ohno-Machado L. Calibrating predictive model estimates to support personalized medicine. J Am Med Inform Assoc. 2012 Mar-Apr; 19(2):263-74. PMID: 21984587.
        View in: PubMed
      103. Ohno-Machado L. Realizing the full potential of electronic health records: the role of natural language processing. J Am Med Inform Assoc. 2011 Sep-Oct; 18(5):539. PMID: 21846784.
        View in: PubMed
      104. Nadkarni PM, Ohno-Machado L, Chapman WW. Natural language processing: an introduction. J Am Med Inform Assoc. 2011 Sep-Oct; 18(5):544-51. PMID: 21846786.
        View in: PubMed
      105. Ohno-Machado L. Biomedical informatics: how we got here and where we are headed. J Am Med Inform Assoc. 2011 Jul-Aug; 18(4):351. PMID: 21672903.
        View in: PubMed
      106. Boxwala AA, Kim J, Grillo JM, Ohno-Machado L. Using statistical and machine learning to help institutions detect suspicious access to electronic health records. J Am Med Inform Assoc. 2011 Jul-Aug; 18(4):498-505. PMID: 21672912.
        View in: PubMed
      107. Sarkar IN, Butte AJ, Lussier YA, Tarczy-Hornoch P, Ohno-Machado L. Translational bioinformatics: linking knowledge across biological and clinical realms. J Am Med Inform Assoc. 2011 Jul-Aug; 18(4):354-7. PMID: 21561873.
        View in: PubMed
      108. Ohno-Machado L. Informatics is about algorithms, systems, people, and social networks. J Am Med Inform Assoc. 2011 May 1; 18(3):209. PMID: 21486878.
        View in: PubMed
      109. Ohno-Machado L. A hybrid open-access model to bridge the publishing divide and reach out to a broader community. J Am Med Inform Assoc. 2011 May 1; 18(3):210-1. PMID: 21486879.
        View in: PubMed
      110. Kim J, Patel K, Jung H, Kuo WP, Ohno-Machado L. AnyExpress: integrated toolkit for analysis of cross-platform gene expression data using a fast interval matching algorithm. BMC Bioinformatics. 2011; 12:75. PMID: 21410990.
        View in: PubMed
      111. Eckert MA, Lwin TM, Chang AT, Kim J, Danis E, Ohno-Machado L, Yang J. Twist1-induced invadopodia formation promotes tumor metastasis. Cancer Cell. 2011 Mar 8; 19(3):372-86. PMID: 21397860.
        View in: PubMed
      112. Jiang X, Osl M, Kim J, Ohno-Machado L. Smooth isotonic regression: a new method to calibrate predictive models. AMIA Summits Transl Sci Proc. 2011; 2011:16-20. PMID: 22211175.
        View in: PubMed
      113. Lehmannm H, Ohno-Machado L. Evaluation of informatics systems: beyond RCTs and beyond the hospital. J Am Med Inform Assoc. 2011 Mar-Apr; 18(2):110-1. PMID: 21385823.
        View in: PubMed
      114. Ohno-Machado L. What's new in informatics. J Am Med Inform Assoc. 2011 Jan-Feb; 18(1):1. PMID: 21169616.
        View in: PubMed
      115. Ohno-Machado L. A new JAMIA. J Am Med Inform Assoc. 2011 Jan-Feb; 18(1):2. PMID: 21169617.
        View in: PubMed
      116. Casas E, Kim J, Bendesky A, Ohno-Machado L, Wolfe CJ, Yang J. Snail2 is an essential mediator of Twist1-induced epithelial mesenchymal transition and metastasis. Cancer Res. 2011 Jan 1; 71(1):245-54. PMID: 21199805.
        View in: PubMed
      117. Kim H, Choi J, Thompson S, Meeker L, Dykes P, Goldsmith D, Ohno-Machado L. Automating pressure ulcer risk assessment using documented patient data. Int J Med Inform. 2010 Dec; 79(12):840-8. PMID: 20869303.
        View in: PubMed
      118. Kim H, Choi J, Secalag L, Dibsie L, Boxwala A, Ohno-Machado L. Building an ontology for pressure ulcer risk assessment to allow data sharing and comparisons across hospitals. AMIA Annu Symp Proc. 2010; 2010:382-6. PMID: 21347005.
        View in: PubMed
      119. Osl M, Dreiseitl S, Kim J, Patel K, Baumgartner C, Ohno-Machado L. Effect of data combination on predictive modeling: a study using gene expression data. AMIA Annu Symp Proc. 2010; 2010:567-71. PMID: 21347042.
        View in: PubMed
      120. Sadow CA, Wheeler SC, Kim J, Ohno-Machado L, Silverman SG. Positive predictive value of CT urography in the evaluation of upper tract urothelial cancer. AJR Am J Roentgenol. 2010 Nov; 195(5):W337-43. PMID: 20966298.
        View in: PubMed
      121. Lacson R, Pitzer E, Kim J, Galante P, Hinske C, Ohno-Machado L. DSGeo: software tools for cross-platform analysis of gene expression data in GEO. J Biomed Inform. 2010 Oct; 43(5):709-15. PMID: 20435161.
        View in: PubMed
      122. Pitzer E, Kim J, Patel K, Galante PA, Ohno-Machado L. PositionMatcher: A Fast Custom-Annotation Tool for Short DNA Sequences. AMIA Summits Transl Sci Proc. 2010; 2010:25-9. PMID: 21347141.
        View in: PubMed
      123. Pitzer E, Lacson R, Hinske C, Kim J, Galante PA, Ohno-Machado L. Towards large-scale sample annotation in gene expression repositories. BMC Bioinformatics. 2009; 10 Suppl 9:S9. PMID: 19761579.
        View in: PubMed
      124. Racowsky C, Ohno-Machado L, Kim J, Biggers JD. Is there an advantage in scoring early embryos on more than one day? Hum Reprod. 2009 Sep; 24(9):2104-13. PMID: 19493872.
        View in: PubMed
      125. Ohno-Machado L, Ellison D, Shortliffe EH. Presentation of the 2008 Morris F. Collen Award to Robert A. Greenes. J Am Med Inform Assoc. 2009 May-Jun; 16(3):413-8. PMID: 19606540.
        View in: PubMed
      126. Matheny ME, Morrow DA, Ohno-Machado L, Cannon CP, Sabatine MS, Resnic FS. Validation of an automated safety surveillance system with prospective, randomized trial data. Med Decis Making. 2009 Mar-Apr; 29(2):247-56. PMID: 19015285.
        View in: PubMed
      127. Curtis DW, Pino EJ, Bailey JM, Shih EI, Waterman J, Vinterbo SA, Stair TO, Guttag JV, Greenes RA, Ohno-Machado L. SMART--an integrated wireless system for monitoring unattended patients. J Am Med Inform Assoc. 2008 Jan-Feb; 15(1):44-53. PMID: 17947629.
        View in: PubMed
      128. Matheny ME, Ohno-Machado L, Resnic FS. Risk-adjusted sequential probability ratio test control chart methods for monitoring operator and institutional mortality rates in interventional cardiology. Am Heart J. 2008 Jan; 155(1):114-20. PMID: 18082501.
        View in: PubMed
      129. Matheny ME, Arora N, Ohno-Machado L, Resnic FS. Rare adverse event monitoring of medical devices with the use of an automated surveillance tool. AMIA Annu Symp Proc. 2007; 518-22. PMID: 18693890.
        View in: PubMed
      130. Matheny ME, Morrow DA, Ohno-Machado L, Cannon CP, Resnic FS. Validating an automated outcomes surveillance application using data from a terminated randomized, controlled trial (OPUS [TIMI-16]). AMIA Annu Symp Proc. 2007; 1043. PMID: 18694141.
        View in: PubMed
      131. Matheny ME, Resnic FS, Arora N, Ohno-Machado L. Effects of SVM parameter optimization on discrimination and calibration for post-procedural PCI mortality. J Biomed Inform. 2007 Dec; 40(6):688-97. PMID: 17600771.
        View in: PubMed
      132. Vinterbo SA, Dreiseitl S, Ohno-Machado L. Approximation properties of haplotype tagging. BMC Bioinformatics. 2006; 7:8. PMID: 16401341.
        View in: PubMed
      133. Ohno-Machado L, Resnic FS, Matheny ME. Prognosis in critical care. Annu Rev Biomed Eng. 2006; 8:567-99. PMID: 16834567.
        View in: PubMed
      134. Matheny ME, Ohno-Machado L, Resnic FS. Monitoring device safety in interventional cardiology. J Am Med Inform Assoc. 2006 Mar-Apr; 13(2):180-7. PMID: 16357356.
        View in: PubMed
      135. Zou KH, Resnic FS, Talos IF, Goldberg-Zimring D, Bhagwat JG, Haker SJ, Kikinis R, Jolesz FA, Ohno-Machado L. A global goodness-of-fit test for receiver operating characteristic curve analysis via the bootstrap method. J Biomed Inform. 2005 Oct; 38(5):395-403. PMID: 16198998.
        View in: PubMed
      136. Vinterbo SA, Kim EY, Ohno-Machado L. Small, fuzzy and interpretable gene expression based classifiers. Bioinformatics. 2005 May 1; 21(9):1964-70. PMID: 15661797.
        View in: PubMed
      137. Matheny ME, Ohno-Machado L, Resnic FS. Exploration of a Bayesian updating tool to provide real-time safety monitoring for new medical devices. AMIA Annu Symp Proc. 2005; 1045. PMID: 16779332.
        View in: PubMed
      138. Ohno-Machado L, Silveira PS, Vinterbo S. Protecting patient privacy by quantifiable control of disclosures in disseminated databases. Int J Med Inform. 2004 Aug; 73(7-8):599-606. PMID: 15246040.
        View in: PubMed
      139. Kuo WP, Kim EY, Trimarchi J, Jenssen TK, Vinterbo SA, Ohno-Machado L. A primer on gene expression and microarrays for machine learning researchers. J Biomed Inform. 2004 Aug; 37(4):293-303. PMID: 15465482.
        View in: PubMed
      140. Resnic FS, Zou KH, Do DV, Apostolakis G, Ohno-Machado L. Exploration of a bayesian updating methodology to monitor the safety of interventional cardiovascular procedures. Med Decis Making. 2004 Jul-Aug; 24(4):399-407. PMID: 15271278.
        View in: PubMed
      141. Weber G, Vinterbo S, Ohno-Machado L. Multivariate selection of genetic markers in diagnostic classification. Artif Intell Med. 2004 Jun; 31(2):155-67. PMID: 15219292.
        View in: PubMed
      142. Albrecht A, Vinterbo SA, Ohno-Machado L. An Epicurean learning approach to gene-expression data classification. Artif Intell Med. 2003 May; 28(1):75-87. PMID: 12850314.
        View in: PubMed
      143. Resnic FS, Wainstein M, Lee MK, Behrendt D, Wainstein RV, Ohno-Machado L, Kirshenbaum JM, Rogers CD, Popma JJ, Piana R. No-reflow is an independent predictor of death and myocardial infarction after percutaneous coronary intervention. Am Heart J. 2003 Jan; 145(1):42-6. PMID: 12514653.
        View in: PubMed
      144. Ohno-Machado L, Vinterbo S, Dreiseitl S, Jenssen TK, Kuo W. Comparing imperfect measurements with the Bland-Altman technique: application in gene expression analysis. Proc AMIA Symp. 2002; 572-6. PMID: 12463888.
        View in: PubMed
      145. Ray HN, Boxwala AA, Anantraman V, Ohno-Machado L. Providing context-sensitive decision-support based on WHO guidelines. Proc AMIA Symp. 2002; 637-41. PMID: 12463901.
        View in: PubMed
      146. Weber G, Vinterbo S, Ohno-Machado L. Building an asynchronous web-based tool for machine learning classification. Proc AMIA Symp. 2002; 869-73. PMID: 12463949.
        View in: PubMed