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Merck Manual on Pharmacokinetics (Professional Version). 2023.
Jennifer Le. . View Publication.
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Antimicrobial Susceptibility of Streptococcus pneumoniae from North America, Europe, Latin America, and the Asia-Pacific Region: Results From 20 Years of the SENTRY Antimicrobial Surveillance Program (1997-2016). Open Forum Infect Dis. 2019 Mar; 6(Suppl 1):S14-S23.
Sader HS, Mendes RE, Le J, Denys G, Flamm RK, Jones RN. PMID: 30895211; PMCID: PMC6419902.
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20
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Cost-effective analysis of low- versus high-dose colistin in the treatment of multi-drug resistant pneumonia in Saudi Arabia. Int J Clin Pharm. 2019 Feb; 41(1):1-2.
Nazer LH, Le J. PMID: 30661216.
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Humans
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Optimizing Antibiotic Drug Therapy in Pediatrics: Current State and Future Needs. J Clin Pharmacol. 2018 10; 58 Suppl 10:S108-S122.
Le J, Bradley JS. PMID: 30248202.
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15 Fields:
Translation:
Humans
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Critical Review of Double-Carbapenem Therapy for the Treatment of Carbapenemase-Producing Klebsiella pneumoniae. Ann Pharmacother. 2019 01; 53(1):70-81.
Mashni O, Nazer L, Le J. PMID: 30019911.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Comparative Analysis of Ampicillin Plasma and Dried Blood Spot Pharmacokinetics in Neonates. Ther Drug Monit. 2018 02; 40(1):103-108.
Le J, Poindexter B, Sullivan JE, Laughon M, Delmore P, Blackford M, Yogev R, James LP, Melloni C, Harper B, Mitchell J, Benjamin DK, Boakye-Agyeman F, Cohen-Wolkowiez M. PMID: 29271816; PMCID: PMC5764797.
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PubMed Mentions:
5 Fields:
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Humans
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Quality and Clinical Outcomes Associated with a Gentamicin Use System Change for Managing Chorioamnionitis. J Med Syst. 2017 Nov 09; 41(12):202.
Sauberan JB, Choi B, Paradyse AR, Le J. PMID: 29124501.
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1 Fields:
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Humans
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Pharmacokinetics of single-dose ceftaroline fosamil in children with cystic fibrosis. Pediatr Pulmonol. 2017 Nov; 52(11):1424-1434.
Le J, Bradley JS, Hingtgen S, Skochko S, Black N, Jones RN, Lim M, Capparelli EV. PMID: 28910514.
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4 Fields:
Translation:
HumansCellsCTClinical Trials
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Augmented Renal Clearance Using Population-Based Pharmacokinetic Modeling in Critically Ill Pediatric Patients. Pediatr Crit Care Med. 2017 Sep; 18(9):e388-e394.
Avedissian SN, Bradley E, Zhang D, Bradley JS, Nazer LH, Tran TM, Nguyen A, Le J. PMID: 28640009.
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29 Fields:
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Humans
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Case report of transient mcr-1-haboring Escherichia coli with concurrent Staphylococcus aureus bacteremia in Long Beach, California. Diagn Microbiol Infect Dis. 2017 Dec; 89(4):303-304.
Le J, Turner N, Deshpande LM, Davis AP, Castanheira M. PMID: 28987268.
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HumansCells
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Minimally Invasive Aortic Valve Replacement via Right Anterior Minithoracotomy and Central Aortic Cannulation: A 13-Year Experience. Innovations (Phila). 2017 Mar/Apr; 12(2):87-94.
Bethencourt DM, Le J, Rodriguez G, Kalayjian RW, Thomas GS. PMID: 28346263.
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PubMed Mentions:
5 Fields:
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Humans
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Pediatric Obesity: Pharmacokinetic Alterations and Effects on Antimicrobial Dosing. Pharmacotherapy. 2017 03; 37(3):361-378.
Natale S, Bradley J, Nguyen WH, Tran T, Ny P, La K, Vivian E, Le J. PMID: 28079262.
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8 Fields:
Translation:
Humans
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Evolution of Ceftaroline-Resistant Mrsa in a Child with Cystic Fibrosis Following Repeated Antibiotic Exposure. Pediatr Infect Dis J. 2016 Jul; 35(7):813-5.
Cannavino CR, Mendes RE, Sader HS, Farrell DJ, Critchley IA, Biek D, Le J, Skochko SM, Jones RN, Bradley JS. PMID: 27093165.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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Vancomycin pharmacokinetics and predicted dosage requirements in pediatric cancer patients. J Oncol Pharm Pract. 2016 Jun; 22(3):448-53.
Abdel Hadi O, Al Omar S, Nazer LH, Mubarak S, Le J. PMID: 26079639.
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PubMed Mentions:
14 Fields:
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HumansCells
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High-dose colistin for microbiologically documented serious respiratory infections associated with carbapenem-resistant Acinetobacter baummannii in critically ill cancer patients: a retrospective cohort study. Infect Dis (Lond). 2015; 47(11):755-60.
Nazer LH, Rihani S, Hawari FI, Le J. PMID: 26050703.
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7 Fields:
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HumansCells
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Bayesian Estimation of Vancomycin Pharmacokinetics in Obese Children: Matched Case-Control Study. Clin Ther. 2015 Jun 01; 37(6):1340-51.
Le J, Capparelli EV, Wahid U, Wu YS, Romanowski GL, Tran TM, Nguyen A, Bradley JS. PMID: 26031618; PMCID: PMC4475435.
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9 Fields:
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Humans
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Effect of nebulized colistin on the ventilator circuit: a prospective pilot case- control study from a single cancer center. Mediterr J Hematol Infect Dis. 2015; 7(1):e2015032.
Ghonimat IM, Nazer LH, Aqel F, Mohammad MK, Hawari FI, Le J. PMID: 25960860; PMCID: PMC4418373.
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Pharmacodynamic Characteristics of Nephrotoxicity Associated With Vancomycin Use in Children. J Pediatric Infect Dis Soc. 2015 Dec; 4(4):e109-16.
Le J, Ny P, Capparelli E, Lane J, Ngu B, Muus R, Romanowski G, Vo T, Bradley J. PMID: 26582878; PMCID: PMC4681388.
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34 Fields:
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Humans
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Vancomycin monitoring in children using bayesian estimation. Ther Drug Monit. 2014 Aug; 36(4):510-8.
Le J, Ngu B, Bradley JS, Murray W, Nguyen A, Nguyen L, Romanowski GL, Vo T, Capparelli EV. PMID: 24452067; PMCID: PMC4101060.
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PubMed Mentions:
14 Fields:
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Humans
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Characterization of the population pharmacokinetics of ampicillin in neonates using an opportunistic study design. Antimicrob Agents Chemother. 2014 Jun; 58(6):3013-20.
Tremoulet A, Le J, Poindexter B, Sullivan JE, Laughon M, Delmore P, Salgado A, Ian-U Chong S, Melloni C, Gao J, Benjamin DK, Capparelli EV, Cohen-Wolkowiez M, Administrative Core Committee of the Best Pharmaceuticals for Children Act-Pediatric Trials Network. PMID: 24614374; PMCID: PMC4068432.
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32 Fields:
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HumansCTClinical Trials
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Population-Based Pharmacokinetic Modeling of Vancomycin in Children with Renal Insufficiency. J Pharmacol Clin Toxicol. 2014; 2(1):1017-1026.
Le J, Vaida F, Nguyen E, Adler-Shohet FC, Romanowski G, Kim J, Vo T, Capparelli EV. PMID: 25309945; PMCID: PMC4191860.
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5
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Maximum tolerated osmolarity for peripheral administration of parenteral nutrition in pediatric patients. JPEN J Parenter Enteral Nutr. 2014 Sep; 38(7):847-51.
Dugan S, Le J, Jew RK. PMID: 23851423.
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6 Fields:
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Humans
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Improved vancomycin dosing in children using area under the curve exposure. Pediatr Infect Dis J. 2013 Apr; 32(4):e155-63.
Le J, Bradley JS, Murray W, Romanowski GL, Tran TT, Nguyen N, Cho S, Natale S, Bui I, Tran TM, Capparelli EV. PMID: 23340565; PMCID: PMC3632448.
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PubMed Mentions:
90 Fields:
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Humans
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Time to initiation of antifungal therapy for neonatal candidiasis. Antimicrob Agents Chemother. 2013 Jun; 57(6):2550-5.
Le J, Tran TT, Bui I, Wang MK, Vo A, Adler-Shohet FC. PMID: 23507285; PMCID: PMC3716169.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
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Foodborne botulism treated with heptavalent botulism antitoxin. Ann Pharmacother. 2013 Feb; 47(2):e12.
Hill SE, Iqbal R, Cadiz CL, Le J. PMID: 23362041.
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PubMed Mentions:
6 Fields:
Translation:
HumansPHPublic Health
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Impact of the use of procalcitonin assay in hospitalized adult patients with pneumonia at a community acute care hospital. Infect Control Hosp Epidemiol. 2012 Apr; 33(4):424-6.
Kook JL, Chao SR, Le J, Robinson PA. PMID: 22418643.
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6 Fields:
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Humans
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In vitro activity of carbapenems alone and in combination with amikacin against KPC-producing Klebsiella pneumoniae. J Clin Med Res. 2011 May 19; 3(3):106-10.
Le J, McKee B, Srisupha-Olarn W, Burgess DS. PMID: 21811540; PMCID: PMC3138406.
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PubMed Mentions:
15
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Incidence and risk factors influencing the development of vancomycin nephrotoxicity in children. J Pediatr. 2011 Mar; 158(3):422-6.
McKamy S, Hernandez E, Jahng M, Moriwaki T, Deveikis A, Le J. PMID: 20888013.
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68 Fields:
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Humans
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Treatment of meningitis caused by vancomycin-resistant Enterococcus faecium: high-dose and combination daptomycin therapy. Ann Pharmacother. 2010 Dec; 44(12):2001-6.
Le J, Bookstaver PB, Rudisill CN, Hashem MG, Iqbal R, James CL, Sakoulas G. PMID: 21119097.
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11 Fields:
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HumansCells
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Complications associated with outpatient parenteral antibiotic therapy in children. Clin Pediatr (Phila). 2010 Nov; 49(11):1038-43.
Le J, San Agustin M, Hernandez EA, Tran TT, Adler-Shohet FC. PMID: 20724346.
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PubMed Mentions:
8 Fields:
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Humans
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Consensus summary of aerosolized antimicrobial agents: application of guideline criteria. Insights from the Society of Infectious Diseases Pharmacists. Pharmacotherapy. 2010 Jun; 30(6):562-84.
Le J, Ashley ED, Neuhauser MM, Brown J, Gentry C, Klepser ME, Marr AM, Schiller D, Schwiesow JN, Tice S, VandenBussche HL, Wood GC, Society of Infectious Diseases Pharmacists Aerosolized Antimicrobials Task Force. PMID: 20500046.
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21 Fields:
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Humans
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Aerosolized Delivery of Antifungal Agents. Curr Fungal Infect Rep. 2010 Jun; 4(2):96-102.
Le J, Schiller DS. PMID: 20502511; PMCID: PMC2868999.
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6
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Clonal dissemination of Klebsiella pneumoniae carbapenemase KPC-3 in Long Beach, California. J Clin Microbiol. 2010 Feb; 48(2):623-5.
Le J, Castanheira M, Burgess DS, McKee B, Iqbal R, Jones RN. PMID: 20032252; PMCID: PMC2815646.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Nephrotoxicity associated with amphotericin B deoxycholate in neonates. Pediatr Infect Dis J. 2009 Dec; 28(12):1061-3.
Le J, Adler-Shohet FC, Nguyen C, Lieberman JM. PMID: 19935267.
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10 Fields:
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Humans
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Impact of empiric antibiotic use on development of infections caused by extended-spectrum beta-lactamase bacteria in a neonatal intensive care unit. Pediatr Infect Dis J. 2008 Apr; 27(4):314-8.
Le J, Nguyen T, Okamoto M, McKamy S, Lieberman JM. PMID: 18316990.
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PubMed Mentions:
15 Fields:
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HumansCells
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Management of community-associated methicillin-resistant Staphylococcus aureus infections in children. Pharmacotherapy. 2006 Dec; 26(12):1758-70.
Le J, Lieberman JM. PMID: 17125437.
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PubMed Mentions:
9 Fields:
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HumansCells
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Adverse drug reactions among children over a 10-year period. Pediatrics. 2006 Aug; 118(2):555-62.
Le J, Nguyen T, Law AV, Hodding J. PMID: 16882807.
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PubMed Mentions:
45 Fields:
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Humans
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Urinary tract infections during pregnancy. Ann Pharmacother. 2004 Oct; 38(10):1692-701.
Le J, Briggs GG, McKeown A, Bustillo G. PMID: 15340129.
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PubMed Mentions:
27 Fields:
Translation:
Humans