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Jennifer Le

Photo of Jennifer Le
Title(s)Professor Of Clinical, School of Pharmacy and Pharmaceutical Science
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
Emailjel078@ucsd.edu
ORCID ORCID Icon0000-0002-6692-0884 Additional info
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    Collapse Overview 
    Collapse overview
    Dr. Le is Professor of Clinical Pharmacy at the UC San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences. Her academic career spans more than 24 years and is distinguished by over 200+ peer-reviewed publications focused on patient-oriented research in clinical pharmacology, including model-informed precision dosing (MIPD), antimicrobial stewardship, resistant infections, medication safety, and national vancomycin and extracorporeal membrane oxygenation (ECMO) guidelines. She has delivered more than 100+ invited lectures nationally and internationally and has served as a preceptor and mentor to over 300 students (including Fulbright scholars), residents, fellows, and early-career faculty.

    Dr. Le’s scholarship and professional leadership extend globally, with sustained contributions to medication safety and antimicrobial optimization throughout Asia (including Vietnam, Singapore, Thailand, China) and Jordan. Her work has supported the development and implementation of evidence based dosing strategies, therapeutic drug monitoring programs, and systems level medication safety initiatives in diverse healthcare settings, spanning academic medical centers, national hospitals, and resource limited environments. Notably, her efforts include advancing global standards for safe and effective antimicrobial use and fostering international collaborations to address antimicrobial resistance and prevent medication-related harm across the lifespan, from infants to geriatrics.

    She served on study sections for the National Institutes of Health (NIH), the Agency for Healthcare Research and Quality (AHRQ), the Patient Centered Outcomes Research Institute (PCORI), the National Science Foundation (NSF), and the American Institute of Biological Sciences (AIBS). Her investigator-initiated research in pediatric clinical pharmacology, antimicrobial stewardship, and medication safety has been supported by more than $11.8 million in competitive funding from the NIH, private and philanthropic foundations. In addition, Dr. Le has served as an advisory board member to the U.S. Food and Drug Administration (FDA) since 2018, contributing expertise in medication safety, pharmacotherapy, infectious diseases, and regulatory science.

    Based on Dr. Le’s extensive expertise, global experience, and board certification in pharmacotherapy with added qualification in infectious diseases, she is exceptionally well positioned to lead multidisciplinary teams of U.S. and international experts to accelerate innovation in medication safety, including infusion and specialty pharmacy services that integrate with home health and ambulatory care models. Her depth of knowledge extends across these domains, including more than 20 years of patient care education and implementation science in model-informed precision dosing, which supported the first vancomycin assay and therapeutic drug monitoring program in Vietnam and informed broader medication safety practices across Asia.

    Collapse Biography 
    Collapse education and training
    University of California San Diego, San Diego, CA06/2019Faculty Leadership Academy
    University of California San Diego, San Diego, CA06/2018Faculty Mentorship Training Program
    University of California San Diego, La Jolla, CAMAS09/2012Clinical Research
    Board of Pharmaceutical Specialties, Washington, DCBCPS08/2007Board Certification in Pharmacotherapy
    Board of Pharmaceutical Specialties, Washington, DCAD-ID08/2008Infectious Diseases Pharmacotherapy
    Long Beach Memorial & Miller Children's Hospital, Long Beach, CA06/2001Pharmacy Practice Residency
    University of California San Francisco, School of Pharmacy, San Francisco, CAPharmD06/2000Pharmacy
    University of California Los Angeles, Los Angeles, CABS06/1995Biology
    Collapse awards and honors
    US Food and Drug Administration (FDA)2018  - 2023Invited Advisory Board Member
    Agency for Healthcare Research and Quality (AHRQ)2020  - 2023Invited Study Section Member
    Pediatric ECMO Anticoagulation CollaborativE (PEACE) Consensus2020  - 2023Invited Expert Panel Member
    Sternfels Prize for Drug Safety Innovation2018Grand Prize Recipient (sternfelsprize.org/winners)
    Infectious Diseases Society of America2017Fellow
    University of California San Diego2013Recognition Award for Outstanding Mentor
    California Society of Health-Systems Pharmacists2013Fellow
    American College of Clinical Pharmacy2011Fellow
    Long Beach Research Symposium2010Research Award for “Complications Associated with S. aureus Bacteremia in Children”
    Western University of Health Sciences, College of Pharmacy2009Faculty Service Award
    Asian Pacific Health Foundation2018  - 2023Invited Board Member
    ECMO-CENTRAL (ECMO ECMOCore Elements Needed for Trials Regulation And quality of Life)2023Invited Panel Member
    Patient-Centered Outcomes Research Institute (PCORI)2022Invited Study Section Member
    National Science Foundation (NSF)2023Invited Study Section Member
    American Institute of Biological Sciences (AIBS)2020Invited Study Section Member
    National Foundation for Infectious Diseases (NFID)2026Maxwell Finland Award Nominee
    UC San Diego Skaggs School of Pharmacy2026Excellence in Trainee Mentoring
    Society of Critical Care Medicine2023Safety Innovation Prize for Model Informed Precision Dosing

    Collapse Research 
    Collapse Featured Publications
    Collapse research activities and funding
    Pediatric Trials Network’s (PTN) Antibiotic Safety in Infants with Complicated Intra-abdominal Infections
    NIH/Duke University HHSN275201000003IAug 1, 2018 - Jul 30, 2019
    Role: Co-Investigator (Pharmacologist)
    Longitudinal Assessment of Beta-lactam Antibiotic Exposure in in Critically Ill Children with Sepsis in the PICU to Predict Dosing Requirements
    NIH R01HD095547Jul 28, 2018 - Jun 30, 2022
    Role: Co-Investigator
    Pediatric and Developmental Pharmacology for Inflammatory and Infectious Diseases
    NIH U54HD090259Sep 20, 2016 - Jun 30, 2021
    Role: Co-Investigator (Director of Community Outreach)
    Academic Training in Therapeutic Advancement for Child Health (ATTACH)
    NIH T32HD087978May 1, 2016 - Apr 30, 2026
    Role: Co-Investigator
    Pharmacokinetic-Pharmacodynamics of Antimicrobials in Resistant Infections
    NIH K23AI089978May 15, 2010 - Apr 30, 2016
    Role: Principal Investigator

    Collapse Featured Content 
    Collapse Featured Videos
    Collapse media links
    Collapse Community and Public Service

    Collapse Bibliographic 
    Collapse publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Merck Manual on Pharmacokinetics (Professional Version). 2026. Jennifer Le. . View Publication.
    2. Transforming long-term post-acute care for the aging population through home infusion therapy in China: an assessment of need and demand (Part 1). Front Public Health. 2026; 14:1761871. Zuo W, Zhou ZY, Do DH, Nguyen AP, Vo C, Tran T, Mei D, Wang S, Li S, Yu J, Yang H, Chen W, Zhao B, Hoang L, Le MT, Cheng FWT, Chang IJ, Le J. PMID: 41859265; PMCID: PMC12997782.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Transforming long-term post-acute care for the aging population through home infusion therapy in China: assurance for quality and safety of care delivery (Part 2). Front Public Health. 2026; 14:1761870. Zuo W, Zhou ZY, Huynh K, Do DH, Mei D, Tran T, Yu J, Yang H, Chen W, Zhao B, Lee VWY, Zhang F, Wang S, Li S, Nguyen AP, Vo C, Shi H, Le J. PMID: 41859251; PMCID: PMC12997790.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Sustaining Health Outside of Hospitals: Home Infusion Therapy for Value-Based Long Term Care. Journal of Global Health. 2025; XV(II)(Fall). 35. Shiferaw A, Patrikyan T, Graham R, Do DH, Nguyen AP, Vo C, Tran T, Nguyen LD, Nguyen DT, Chang YL, Chiang SC, Lye A, Rerungjarearnrung K, Tangaroonsanti G, Shoji K, Nguyen HD, Le BH, Nguyen TH, Thi Nguyen, ... and Le Jennifer. View Publication.
    5. Metabolomics of Sepsis and Acute Kidney Injury in Infants and Children: Current Challenges in Prevention, Diagnosis, and Management. Infect Dis Ther. 2025 Dec; 14(12):2639-2656. Koko V, Nguyen V, Avedissian SN, Son D, Trinh V, Tran K, Do DH, Tran TM, Hoang L, Wang Z, Abdul-Mutakabbir J, Le J. PMID: 41102440; PMCID: PMC12602828.
      View in: PubMed   Mentions: 1  
    6. Current state of microbiota clinical applications in neonatal and pediatric bacterial infections. Gut Microbes. 2025 Dec; 17(1):2529400. Le TT, Hoang TN, Do DH, Nguyen XH, Huynh C, Viet HD, Dat VQ, Zengler K, Gilbert JA, Avedissian SN, Tran TM, Le J. PMID: 40618377; PMCID: PMC12233708.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    7. Dosing Recommendations for Ampicillin and Ceftriaxone in the Treatment of Pediatric Community-Acquired Pneumonia Using Monte Carlo- and Physiologic-Based Pharmacokinetic Simulations. J Pediatr Pharmacol Ther. 2025 Jun; 30(3):352-361. Tung N, Huynh D, Dam Q, Tran T, Hulten KG, Harrison CJ, Kaplan SL, Do TH, Setty A, Hoang L, Bradley JS, Le J. PMID: 40534929; PMCID: PMC12172679.
      View in: PubMed   Mentions:
    8. Variability in Meropenem Distribution and Clearance in Children with Sepsis: Population-Based Pharmacokinetics with Assessment of Renal Biomarkers. Clin Pharmacokinet. 2025 May; 64(5):769-777. Le J, Huynh J, Vo B, Mai A, Mak RH, Momper JD, Capparelli EV, Harvey H, Avedissian S, Bradley E, Sitapati A, Singh K, Bradley JS. PMID: 40272699; PMCID: PMC12064575.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Model-Informed Precision Dosing of Vancomycin in Vietnamese Children: Innovative Midpoint Concentration Monitoring Using 2 Bayesian Programs. Ther Drug Monit. 2025 Oct 01; 47(5):603-608. Hai Le B, Phung CK, Yip O, Gupta A, Phan TL, Lai H, Hoang L, Nguyen TH, Nguyen TD, Nguyen TT, Nguyen TLH, Le J. PMID: 40152654.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    10. Subtherapeutic Meropenem Antibiotic Exposure in Children With Septic Shock Assessed by Noncompartmental Pharmacokinetic Analysis in a Prospective Dataset. Pediatr Crit Care Med. 2025 Apr 01; 26(4):e507-e515. Bradley JS, Harvey H, Stout D, Momper J, Capparelli E, Avedissian SN, Barbato C, Mak RH, Jones TP, Jones D, Le J. PMID: 39964222; PMCID: PMC11960678.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    11. Definitions of adverse events associated with extracorporeal membrane oxygenation in children: results of an international Delphi process from the ECMO-CENTRAL ARC. Lancet Child Adolesc Health. 2024 10; 8(10):773-780. Alexander PMA, Di Nardo M, Combes A, Vogel AM, Antonini MV, Barrett N, Benedetti GM, Bettencourt A, Brodie D, Gómez-Gutiérrez R, Gorga SM, Hodgson C, Kapoor PM, Le J, MacLaren G, O'Neil ER, Ostermann M, Paden ML, Patel N, Rojas-Peña A, Said AS, Sperotto F, Willems A, Vercaemst L, Yoganathan AP, Lorts A, Del Nido PJ, Barbaro RP, Extracorporeal Life Support Organization (ELSO), International ECMO Network (ECMONet), Pediatric Acute Lung Injury and Sepsis Investigators (PALISI), Pediatric ECMO subgroup of PALISI and ELSO (PediECMO), European Society of Paediatric and Neonatal Intensive Care (ESPNIC), Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG), Intensive Care Society (ICS), Pediatric Cardiac Intensive Care Society (PCICS), Advanced Cardiac Therapies Improving Outcomes Network (ACTION), Children's Hospitals Neonatal Consortium (CHNC), American Pediatric Surgical Association (APSA), Society of Thoracic Surgeons (STS), Society of Critical Care Medicine (SCCM). PMID: 39299748; PMCID: PMC12917940.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    12. Congenital Syphilis-Comprehensive Narrative Review of Alternative Antibiotic Treatment for Use in Neonates. Sex Transm Dis. 2024 12 01; 51(12):775-779. Villarreal DD, Le J, Klausner JD. PMID: 39046152; PMCID: PMC11560590.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    13. Antifibrinolytic and Adjunct Hemostatic Agents: The Pediatric Extracorporeal Membrane Oxygenation Anticoagulation CollaborativE Consensus Conference. Pediatr Crit Care Med. 2024 Jul 01; 25(7 Suppl 1):e44-e52. Moynihan KM, Ryerson LM, Le J, Nicol K, Watt K, Gadepalli SK, Alexander PMA, Muszynski JA, Gehred A, Lyman E, Steiner ME, Pediatric Extracorporeal Membrane Oxygenation (ECMO) Anticoagulation CollaborativE (PEACE), in colla. PMID: 38959359; PMCID: PMC11216380.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    14. Anticoagulant Medications: The Pediatric Extracorporeal Membrane Oxygenation Anticoagulation CollaborativE Consensus Conference. Pediatr Crit Care Med. 2024 Jul 01; 25(7 Suppl 1):e7-e13. Cashen K, Saini A, Brandão LR, Le J, Monagle P, Moynihan KM, Ryerson LM, Gehred A, Lyman E, Muszynski JA, Alexander PMA, Dalton HJ, Pediatric Extracorporeal Membrane Oxygenation (ECMO) Anticoagulation CollaborativE (PEACE), in colla. PMID: 38959355; PMCID: PMC11216397.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    15. Executive Summary: The Pediatric Extracorporeal Membrane Oxygenation Anticoagulation CollaborativE (PEACE) Consensus Conference. Pediatr Crit Care Med. 2024 Jul 01; 25(7):643-675. Alexander PMA, Bembea MM, Cashen K, Cheifetz IM, Dalton HJ, Himebauch AS, Karam O, Moynihan KM, Nellis ME, Ozment C, Raman L, Rintoul NE, Said AS, Saini A, Steiner ME, Thiagarajan RR, Watt K, Willems A, Zantek ND, Barbaro RP, Steffen K, Vogel AM, Almond C, Anders MM, Annich GM, Brandão LR, Chandler W, Delaney M, DiGeronimo R, Emani S, Gadepalli SK, Garcia AV, Haileselassie B, Hyslop R, Kneyber MCJ, Baumann Kreuziger L, Le J, Loftis L, McMichael ABV, McMullan DM, Monagle P, Nicol K, Paden ML, Patregnani J, Priest J, Raffini L, Ryerson LM, Sloan SR, Teruya J, Yates AR, Gehred A, Lyman E, Muszynski JA, Pediatric ECMO Anticoagulation CollaborativE (PEACE), in collaboration with the Pediatric Acute Lung. PMID: 38959353; PMCID: PMC11216385.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    16. Postdiscontinuation Antibiotic Exposure in Hospitalized Infants at Risk for Late-onset Sepsis in the Neonatal Intensive Care Unit. Pediatr Infect Dis J. 2024 Oct 01; 43(10):991-996. Wade KC, Greenberg RG, Benjamin DK, Chen LL, Vo B, Ang BL, Boutzoukas A, Zimmerman K, Clark RH, Cohen-Wolkowiez M, Le J, Administrative Core Committee of the Best Pharmaceuticals for Children Act – Pediatric Trials Networ. PMID: 38900075; PMCID: PMC11408093.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    17. Racial Health Disparity Associated With Poor Pediatric Cardiac Surgery Outcomes: A Multicentered, Cross-Sectional Study. JACC Adv. 2024 Jul; 3(7):100987. Setty SP, Reynolds LC, Chou VC, Yu MT, Kang S, Allen PM, Tran L, Le J. PMID: 39130020; PMCID: PMC11313035.
      View in: PubMed   Mentions: 1  
    18. Establishment of a Four-Cell In Vitro Blood-Brain Barrier Model With Human Primary Brain Cells. Curr Protoc. 2024 Jun; 4(6):e1067. Malik JR, Modebelu UO, Fletcher CV, Podany AT, Scarsi KK, Byrareddy SN, Anand RK, Buch S, Sil S, Le J, Bradley JS, Brown AN, Sutar D, Avedissian SN. PMID: 38857108; PMCID: PMC11783448.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    19. Chemotherapy in pediatric brain tumor and the challenge of the blood-brain barrier. Cancer Med. 2023 12; 12(23):21075-21096. Malik JR, Podany AT, Khan P, Shaffer CL, Siddiqui JA, Baranowska-Kortylewicz J, Le J, Fletcher CV, Ether SA, Avedissian SN. PMID: 37997517; PMCID: PMC10726873.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    20. Enhancing pharmacokinetic and pharmacodynamic knowledge in pediatrics. Pharmacotherapy. 2023 07; 43(7):578. Le J, Ramsey LB. PMID: 37435987.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    21. Amoxicillin and penicillin G dosing in pediatric community-acquired pneumococcal pneumonia in the era of conjugate pneumococcal vaccines. Pharmacotherapy. 2024 Aug; 44(8):606-614. Huynh D, Tung N, Dam Q, Tran T, Hulten KG, Harrison CJ, Kaplan SL, Nguyen A, Do TH, Setty A, Le J. PMID: 36571459.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    22. Ampicillin dosing in premature infants for early-onset sepsis: exposure-driven efficacy, safety, and stewardship. J Perinatol. 2022 07; 42(7):959-964. Le J, Greenberg RG, Yoo Y, Clark RH, Benjamin DK, Zimmerman KO, Cohen-Wolkowiez M, Wade KC, Best Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee. PMID: 35210541; PMCID: PMC9262754.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    23. Vancomycin therapeutic monitoring by measured trough concentration versus Bayesian-derived area under the curve in critically ill patients with cancer. Pharmacol Res Perspect. 2022 02; 10(1):e00912. AbuSara AK, Abdelrahman DH, Habash KI, Al-Shaer MH, Le J, Nazer LH. PMID: 34990089; PMCID: PMC8929348.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    24. Questions on Vancomycin Dosing. Clin Infect Dis. 2021 10 05; 73(7):e1777-e1778. Rybak MJ, Le J, Lodise TP, Levine DP, Bradley JS, Liu C, Mueller BA, Pai MP, Wong-Beringer A, Rodvold KA, Maples HD. PMID: 33238295.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    25. Comment on: AUCs and 123s: a critical appraisal of vancomycin therapeutic drug monitoring in paediatrics. J Antimicrob Chemother. 2021 08 12; 76(9):2486-2488. Avedissian SN, Le J, Neely MN, Cortés-Penfield N, Bradley J, Rybak MJ, Rhodes NJ. PMID: 34021756.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    26. Validity of 2020 vancomycin consensus recommendations and further guidance for practical application. Am J Health Syst Pharm. 2021 07 22; 78(15):1364-1367. Rybak MJ, Le J, Lodise TP, Levine DP, Bradley JS, Liu C, Mueller BA, Pai MP, Beringer AW, Rodvold KA, Maples HD. PMID: 33764403.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    27. Prolonged Post-Discontinuation Antibiotic Exposure in Very Low Birth Weight Neonates at Risk for Early-Onset Sepsis. J Pediatric Infect Dis Soc. 2021 May 28; 10(5):615-621. Le J, Greenberg RG, Benjamin DK, Yoo Y, Zimmerman KO, Cohen-Wolkowiez M, Wade KC, Administrative Core Committee of the Best Pharmaceuticals for Children Act–Pediatric Trials Network . PMID: 33491088; PMCID: PMC8163059.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    28. Optimizing Aminoglycoside Dosing Regimens for Critically Ill Pediatric Patients with Augmented Renal Clearance: a Convergence of Parametric and Nonparametric Population Approaches. Antimicrob Agents Chemother. 2021 03 18; 65(4). Avedissian SN, Rohani R, Bradley J, Le J, Rhodes NJ. PMID: 33526481; PMCID: PMC8097479.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    29. Antimicrobial prescribing for treatment of serious infections caused by Staphylococcus aureus and methicillin-resistant Staphylococcus aureus in pediatrics: an expert review. Expert Rev Anti Infect Ther. 2021 09; 19(9):1107-1116. Avedissian SN, Rhodes NJ, Shaffer CL, Tran L, Bradley JS, Le J. PMID: 33554692.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    30. Effect of antidepressant use on length of hospitalization in patients on anti-infective therapy. J Psychiatr Res. 2021 02; 134:97-101. Jones JF, Le J, Lee KC. PMID: 33383496.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    31. Pharmacokinetics/Pharmacodynamics of Antiviral Agents Used to Treat SARS-CoV-2 and Their Potential Interaction with Drugs and Other Supportive Measures: A Comprehensive Review by the PK/PD of Anti-Infectives Study Group of the European Society of Antimicrobial Agents. Clin Pharmacokinet. 2020 10; 59(10):1195-1216. Zeitlinger M, Koch BCP, Bruggemann R, De Cock P, Felton T, Hites M, Le J, Luque S, MacGowan AP, Marriott DJE, Muller AE, Nadrah K, Paterson DL, Standing JF, Telles JP, Wölfl-Duchek M, Thy M, Roberts JA, PK/PD of Anti-Infectives Study Group (EPASG) of the European Society of Clinical Microbiology, Infec. PMID: 32725382; PMCID: PMC7385074.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCellsPHPublic Health
    32. Therapeutic Monitoring of Vancomycin for Serious Methicillin-resistant Staphylococcus aureus Infections: A Revised Consensus Guideline and Review by the American Society of Health-system Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists. Clin Infect Dis. 2020 09 12; 71(6):1361-1364. Rybak MJ, Le J, Lodise TP, Levine DP, Bradley JS, Liu C, Mueller BA, Pai MP, Wong-Beringer A, Rotschafer JC, Rodvold KA, Maples HD, Lomaestro B. PMID: 32658968.
      View in: PubMed   Mentions: 103     Fields:    Translation:HumansCells
    33. Emerging Viral and Bacterial Infections: Within an Era of Opioid Epidemic. Infect Dis Ther. 2020 Dec; 9(4):737-755. Jones JF, Legaspi J, Chen E, Lee K, Le J. PMID: 32918275; PMCID: PMC7680496.
      View in: PubMed   Mentions:
    34. Paradoxical Antibiotic Effect of Ampicillin: Use of a Population Pharmacokinetic Model to Evaluate a Clinical Correlate of the Eagle Effect in Infants With Bacteremia. Pediatr Infect Dis J. 2020 08; 39(8):725-729. Ericson JE, Hornik CP, Greenberg RG, Clark RH, Tremoulet AH, Le J, Cohen-Wolkowiez M, Smith PB, Benjamin DK, Best Pharmaceuticals for Children Act – Pediatric Trials Network. PMID: 32235247; PMCID: PMC8628496.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    35. Executive Summary: Therapeutic Monitoring of Vancomycin for Serious Methicillin-Resistant Staphylococcus aureus Infections: A Revised Consensus Guideline and Review of the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists. J Pediatric Infect Dis Soc. 2020 07 13; 9(3):281-284. Rybak MJ, Le J, Lodise T, Levine D, Bradley J, Liu C, Mueller B, Pai M, Wong-Beringer A, Rotschafer JC, Rodvold K, Maples HD, Lomaestro BM. PMID: 32659787; PMCID: PMC7358040.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    36. Therapeutic monitoring of vancomycin for serious methicillin-resistant Staphylococcus aureus infections: A revised consensus guideline and review by the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists. Am J Health Syst Pharm. 2020 05 19; 77(11):835-864. Rybak MJ, Le J, Lodise TP, Levine DP, Bradley JS, Liu C, Mueller BA, Pai MP, Wong-Beringer A, Rotschafer JC, Rodvold KA, Maples HD, Lomaestro BM. PMID: 32191793.
      View in: PubMed   Mentions: 505     Fields:    Translation:Humans
    37. Executive Summary: Therapeutic Monitoring of Vancomycin for Serious Methicillin-Resistant Staphylococcus aureus Infections: A Revised Consensus Guideline and Review of the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists. Pharmacotherapy. 2020 04; 40(4):363-367. Rybak MJ, Le J, Lodise TP, Levine DP, Bradley JS, Liu C, Mueller BA, Pai MP, Wong-Beringer A, Rotschafer JC, Rodvold KA, Maples HD, Lomaestro BM. PMID: 32227354.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    38. Augmented renal clearance of aminoglycosides using population-based pharmacokinetic modelling with Bayesian estimation in the paediatric ICU. J Antimicrob Chemother. 2020 01 01; 75(1):162-169. Avedissian SN, Rhodes NJ, Kim Y, Bradley J, Valdez JL, Le J. PMID: 31648297.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    39. Use of Simulation Strategies to Predict Subtherapeutic Meropenem Exposure Caused by Augmented Renal Clearance in Critically Ill Pediatric Patients With Sepsis. J Pediatr Pharmacol Ther. 2020; 25(5):413-422. Avedissian SN, Skochko SM, Le J, Hingtgen S, Harvey H, Capparelli EV, Richardson A, Momper J, Mak RH, Neely M, Bradley JS. PMID: 32641911; PMCID: PMC7337137.
      View in: PubMed   Mentions: 11  
    40. Antimicrobial Susceptibility of Streptococcus pneumoniae from North America, Europe, Latin America, and the Asia-Pacific Region: Results From 20 Years of the SENTRY Antimicrobial Surveillance Program (1997-2016). Open Forum Infect Dis. 2019 Mar; 6(Suppl 1):S14-S23. Sader HS, Mendes RE, Le J, Denys G, Flamm RK, Jones RN. PMID: 30895211; PMCID: PMC6419902.
      View in: PubMed   Mentions: 37  
    41. Cost-effective analysis of low- versus high-dose colistin in the treatment of multi-drug resistant pneumonia in Saudi Arabia. Int J Clin Pharm. 2019 Feb; 41(1):1-2. Nazer LH, Le J. PMID: 30661216.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    42. Optimizing Antibiotic Drug Therapy in Pediatrics: Current State and Future Needs. J Clin Pharmacol. 2018 10; 58 Suppl 10:S108-S122. Le J, Bradley JS. PMID: 30248202.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    43. Critical Review of Double-Carbapenem Therapy for the Treatment of Carbapenemase-Producing Klebsiella pneumoniae. Ann Pharmacother. 2019 01; 53(1):70-81. Mashni O, Nazer L, Le J. PMID: 30019911.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    44. Comparative Analysis of Ampicillin Plasma and Dried Blood Spot Pharmacokinetics in Neonates. Ther Drug Monit. 2018 02; 40(1):103-108. Le J, Poindexter B, Sullivan JE, Laughon M, Delmore P, Blackford M, Yogev R, James LP, Melloni C, Harper B, Mitchell J, Benjamin DK, Boakye-Agyeman F, Cohen-Wolkowiez M. PMID: 29271816; PMCID: PMC5764797.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    45. Quality and Clinical Outcomes Associated with a Gentamicin Use System Change for Managing Chorioamnionitis. J Med Syst. 2017 Nov 09; 41(12):202. Sauberan JB, Choi B, Paradyse AR, Le J. PMID: 29124501.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    46. Pharmacokinetics of single-dose ceftaroline fosamil in children with cystic fibrosis. Pediatr Pulmonol. 2017 Nov; 52(11):1424-1434. Le J, Bradley JS, Hingtgen S, Skochko S, Black N, Jones RN, Lim M, Capparelli EV. PMID: 28910514.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCellsCTClinical Trials
    47. Augmented Renal Clearance Using Population-Based Pharmacokinetic Modeling in Critically Ill Pediatric Patients. Pediatr Crit Care Med. 2017 Sep; 18(9):e388-e394. Avedissian SN, Bradley E, Zhang D, Bradley JS, Nazer LH, Tran TM, Nguyen A, Le J. PMID: 28640009.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    48. Case report of transient mcr-1-haboring Escherichia coli with concurrent Staphylococcus aureus bacteremia in Long Beach, California. Diagn Microbiol Infect Dis. 2017 Dec; 89(4):303-304. Le J, Turner N, Deshpande LM, Davis AP, Castanheira M. PMID: 28987268.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    49. Minimally Invasive Aortic Valve Replacement via Right Anterior Minithoracotomy and Central Aortic Cannulation: A 13-Year Experience. Innovations (Phila). 2017 Mar/Apr; 12(2):87-94. Bethencourt DM, Le J, Rodriguez G, Kalayjian RW, Thomas GS. PMID: 28346263.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    50. Pediatric Obesity: Pharmacokinetic Alterations and Effects on Antimicrobial Dosing. Pharmacotherapy. 2017 03; 37(3):361-378. Natale S, Bradley J, Nguyen WH, Tran T, Ny P, La K, Vivian E, Le J. PMID: 28079262.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    51. Evolution of Ceftaroline-Resistant Mrsa in a Child with Cystic Fibrosis Following Repeated Antibiotic Exposure. Pediatr Infect Dis J. 2016 Jul; 35(7):813-5. Cannavino CR, Mendes RE, Sader HS, Farrell DJ, Critchley IA, Biek D, Le J, Skochko SM, Jones RN, Bradley JS. PMID: 27093165.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    52. Vancomycin pharmacokinetics and predicted dosage requirements in pediatric cancer patients. J Oncol Pharm Pract. 2016 Jun; 22(3):448-53. Abdel Hadi O, Al Omar S, Nazer LH, Mubarak S, Le J. PMID: 26079639.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    53. High-dose colistin for microbiologically documented serious respiratory infections associated with carbapenem-resistant Acinetobacter baummannii in critically ill cancer patients: a retrospective cohort study. Infect Dis (Lond). 2015; 47(11):755-60. Nazer LH, Rihani S, Hawari FI, Le J. PMID: 26050703.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    54. Bayesian Estimation of Vancomycin Pharmacokinetics in Obese Children: Matched Case-Control Study. Clin Ther. 2015 Jun 01; 37(6):1340-51. Le J, Capparelli EV, Wahid U, Wu YS, Romanowski GL, Tran TM, Nguyen A, Bradley JS. PMID: 26031618; PMCID: PMC4475435.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    55. Effect of nebulized colistin on the ventilator circuit: a prospective pilot case- control study from a single cancer center. Mediterr J Hematol Infect Dis. 2015; 7(1):e2015032. Ghonimat IM, Nazer LH, Aqel F, Mohammad MK, Hawari FI, Le J. PMID: 25960860; PMCID: PMC4418373.
      View in: PubMed   Mentions:
    56. Pharmacodynamic Characteristics of Nephrotoxicity Associated With Vancomycin Use in Children. J Pediatric Infect Dis Soc. 2015 Dec; 4(4):e109-16. Le J, Ny P, Capparelli E, Lane J, Ngu B, Muus R, Romanowski G, Vo T, Bradley J. PMID: 26582878; PMCID: PMC4681388.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    57. Vancomycin monitoring in children using bayesian estimation. Ther Drug Monit. 2014 Aug; 36(4):510-8. Le J, Ngu B, Bradley JS, Murray W, Nguyen A, Nguyen L, Romanowski GL, Vo T, Capparelli EV. PMID: 24452067; PMCID: PMC4101060.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    58. A formal mentorship program for faculty development. Am J Pharm Educ. 2014 Jun 17; 78(5):100. Jackevicius CA, Le J, Nazer L, Hess K, Wang J, Law AV. PMID: 24954940; PMCID: PMC4064477.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    59. Characterization of the population pharmacokinetics of ampicillin in neonates using an opportunistic study design. Antimicrob Agents Chemother. 2014 Jun; 58(6):3013-20. Tremoulet A, Le J, Poindexter B, Sullivan JE, Laughon M, Delmore P, Salgado A, Ian-U Chong S, Melloni C, Gao J, Benjamin DK, Capparelli EV, Cohen-Wolkowiez M, Administrative Core Committee of the Best Pharmaceuticals for Children Act-Pediatric Trials Network. PMID: 24614374; PMCID: PMC4068432.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCTClinical Trials
    60. Population-Based Pharmacokinetic Modeling of Vancomycin in Children with Renal Insufficiency. J Pharmacol Clin Toxicol. 2014; 2(1):1017-1026. Le J, Vaida F, Nguyen E, Adler-Shohet FC, Romanowski G, Kim J, Vo T, Capparelli EV. PMID: 25309945; PMCID: PMC4191860.
      View in: PubMed   Mentions: 7  
    61. Maximum tolerated osmolarity for peripheral administration of parenteral nutrition in pediatric patients. JPEN J Parenter Enteral Nutr. 2014 Sep; 38(7):847-51. Dugan S, Le J, Jew RK. PMID: 23851423.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    62. Improved vancomycin dosing in children using area under the curve exposure. Pediatr Infect Dis J. 2013 Apr; 32(4):e155-63. Le J, Bradley JS, Murray W, Romanowski GL, Tran TT, Nguyen N, Cho S, Natale S, Bui I, Tran TM, Capparelli EV. PMID: 23340565; PMCID: PMC3632448.
      View in: PubMed   Mentions: 105     Fields:    Translation:Humans
    63. Time to initiation of antifungal therapy for neonatal candidiasis. Antimicrob Agents Chemother. 2013 Jun; 57(6):2550-5. Le J, Tran TT, Bui I, Wang MK, Vo A, Adler-Shohet FC. PMID: 23507285; PMCID: PMC3716169.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    64. Foodborne botulism treated with heptavalent botulism antitoxin. Ann Pharmacother. 2013 Feb; 47(2):e12. Hill SE, Iqbal R, Cadiz CL, Le J. PMID: 23362041.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansPHPublic Health
    65. Impact of the use of procalcitonin assay in hospitalized adult patients with pneumonia at a community acute care hospital. Infect Control Hosp Epidemiol. 2012 Apr; 33(4):424-6. Kook JL, Chao SR, Le J, Robinson PA. PMID: 22418643.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    66. Impact of a faculty orientation and development committee. Am J Pharm Educ. 2012 Feb 10; 76(1):3. Law AV, Jackevicius C, Murray WI, Hess K, Pham DQ, Min DI, Le J. PMID: 22412202; PMCID: PMC3298401.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    67. In vitro activity of carbapenems alone and in combination with amikacin against KPC-producing Klebsiella pneumoniae. J Clin Med Res. 2011 May 19; 3(3):106-10. Le J, McKee B, Srisupha-Olarn W, Burgess DS. PMID: 21811540; PMCID: PMC3138406.
      View in: PubMed   Mentions: 19  
    68. Incidence and risk factors influencing the development of vancomycin nephrotoxicity in children. J Pediatr. 2011 Mar; 158(3):422-6. McKamy S, Hernandez E, Jahng M, Moriwaki T, Deveikis A, Le J. PMID: 20888013.
      View in: PubMed   Mentions: 73     Fields:    Translation:Humans
    69. Treatment of meningitis caused by vancomycin-resistant Enterococcus faecium: high-dose and combination daptomycin therapy. Ann Pharmacother. 2010 Dec; 44(12):2001-6. Le J, Bookstaver PB, Rudisill CN, Hashem MG, Iqbal R, James CL, Sakoulas G. PMID: 21119097.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    70. Complications associated with outpatient parenteral antibiotic therapy in children. Clin Pediatr (Phila). 2010 Nov; 49(11):1038-43. Le J, San Agustin M, Hernandez EA, Tran TT, Adler-Shohet FC. PMID: 20724346.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    71. Consensus summary of aerosolized antimicrobial agents: application of guideline criteria. Insights from the Society of Infectious Diseases Pharmacists. Pharmacotherapy. 2010 Jun; 30(6):562-84. Le J, Ashley ED, Neuhauser MM, Brown J, Gentry C, Klepser ME, Marr AM, Schiller D, Schwiesow JN, Tice S, VandenBussche HL, Wood GC, Society of Infectious Diseases Pharmacists Aerosolized Antimicrobials Task Force. PMID: 20500046.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    72. Aerosolized Delivery of Antifungal Agents. Curr Fungal Infect Rep. 2010 Jun; 4(2):96-102. Le J, Schiller DS. PMID: 20502511; PMCID: PMC2868999.
      View in: PubMed   Mentions: 8  
    73. Clonal dissemination of Klebsiella pneumoniae carbapenemase KPC-3 in Long Beach, California. J Clin Microbiol. 2010 Feb; 48(2):623-5. Le J, Castanheira M, Burgess DS, McKee B, Iqbal R, Jones RN. PMID: 20032252; PMCID: PMC2815646.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    74. Nephrotoxicity associated with amphotericin B deoxycholate in neonates. Pediatr Infect Dis J. 2009 Dec; 28(12):1061-3. Le J, Adler-Shohet FC, Nguyen C, Lieberman JM. PMID: 19935267.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    75. Impact of empiric antibiotic use on development of infections caused by extended-spectrum beta-lactamase bacteria in a neonatal intensive care unit. Pediatr Infect Dis J. 2008 Apr; 27(4):314-8. Le J, Nguyen T, Okamoto M, McKamy S, Lieberman JM. PMID: 18316990.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    76. Management of community-associated methicillin-resistant Staphylococcus aureus infections in children. Pharmacotherapy. 2006 Dec; 26(12):1758-70. Le J, Lieberman JM. PMID: 17125437.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    77. Adverse drug reactions among children over a 10-year period. Pediatrics. 2006 Aug; 118(2):555-62. Le J, Nguyen T, Law AV, Hodding J. PMID: 16882807.
      View in: PubMed   Mentions: 56     Fields:    Translation:Humans
    78. Urinary tract infections during pregnancy. Ann Pharmacother. 2004 Oct; 38(10):1692-701. Le J, Briggs GG, McKeown A, Bustillo G. PMID: 15340129.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans

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