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Jennifer Le

TitleProfessor Of Clinical
InstitutionUniversity of California San Diego
DepartmentSchool of Pharmacy and Pharmaceutical Science
Address9500 Gilman Drive #0714
La Jolla CA 92093
Phone858-534-3692
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    Collapse Research 
    Collapse Research Activities and Funding
    Pharmacokinetic-Pharmacodynamics of Antimicrobials in Resistant Infections
    NIH/NIAID K23AI089978May 15, 2010 - Apr 30, 2015
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Le J, Poindexter B, Sullivan JE, Laughon M, Delmore P, Blackford M, Yogev R, James LP, Melloni C, Harper B, Mitchell J, Benjamin DK, Boakye-Agyeman F, Cohen-Wolkowiez M. Comparative Analysis of Ampicillin Plasma and Dried Blood Spot Pharmacokinetics in Neonates. Ther Drug Monit. 2018 Feb; 40(1):103-108. PMID: 29271816.
      View in: PubMed
    2. Sauberan JB, Choi B, Paradyse AR, Le J. Quality and Clinical Outcomes Associated with a Gentamicin Use System Change for Managing Chorioamnionitis. J Med Syst. 2017 Nov 09; 41(12):202. PMID: 29124501.
      View in: PubMed
    3. Le J, Bradley JS, Hingtgen S, Skochko S, Black N, Jones RN, Lim M, Capparelli EV. Pharmacokinetics of single-dose ceftaroline fosamil in children with cystic fibrosis. Pediatr Pulmonol. 2017 Nov; 52(11):1424-1434. PMID: 28910514.
      View in: PubMed
    4. Avedissian SN, Bradley E, Zhang D, Bradley JS, Nazer LH, Tran TM, Nguyen A, Le J. Augmented Renal Clearance Using Population-Based Pharmacokinetic Modeling in Critically Ill Pediatric Patients. Pediatr Crit Care Med. 2017 Sep; 18(9):e388-e394. PMID: 28640009.
      View in: PubMed
    5. Le J, Turner N, Deshpande LM, Davis AP, Castanheira M. Case report of transient mcr-1-haboring Escherichia coli with concurrent Staphylococcus aureus bacteremia in Long Beach, California. Diagn Microbiol Infect Dis. 2017 Dec; 89(4):303-304. PMID: 28987268.
      View in: PubMed
    6. Bethencourt DM, Le J, Rodriguez G, Kalayjian RW, Thomas GS. Minimally Invasive Aortic Valve Replacement via Right Anterior Minithoracotomy and Central Aortic Cannulation: A 13-Year Experience. Innovations (Phila). 2017 Mar/Apr; 12(2):87-94. PMID: 28346263.
      View in: PubMed
    7. Natale S, Bradley J, Nguyen WH, Tran T, Ny P, La K, Vivian E, Le J. Pediatric Obesity: Pharmacokinetic Alterations and Effects on Antimicrobial Dosing. Pharmacotherapy. 2017 Mar; 37(3):361-378. PMID: 28079262.
      View in: PubMed
    8. Cannavino CR, Mendes RE, Sader HS, Farrell DJ, Critchley IA, Biek D, Le J, Skochko SM, Jones RN, Bradley JS. Evolution of Ceftaroline-Resistant Mrsa in a Child with Cystic Fibrosis Following Repeated Antibiotic Exposure. Pediatr Infect Dis J. 2016 Jul; 35(7):813-5. PMID: 27093165.
      View in: PubMed
    9. Abdel Hadi O, Al Omar S, Nazer LH, Mubarak S, Le J. Vancomycin pharmacokinetics and predicted dosage requirements in pediatric cancer patients. J Oncol Pharm Pract. 2016 Jun; 22(3):448-53. PMID: 26079639.
      View in: PubMed
    10. Nazer LH, Rihani S, Hawari FI, Le J. High-dose colistin for microbiologically documented serious respiratory infections associated with carbapenem-resistant Acinetobacter baummannii in critically ill cancer patients: a retrospective cohort study. Infect Dis (Lond). 2015; 47(11):755-60. PMID: 26050703.
      View in: PubMed
    11. Le J, Capparelli EV, Wahid U, Wu YS, Romanowski GL, Tran TM, Nguyen A, Bradley JS. Bayesian Estimation of Vancomycin Pharmacokinetics in Obese Children: Matched Case-Control Study. Clin Ther. 2015 Jun 01; 37(6):1340-51. PMID: 26031618; PMCID: PMC4475435.
    12. Ghonimat IM, Nazer LH, Aqel F, Mohammad MK, Hawari FI, Le J. Effect of nebulized colistin on the ventilator circuit: a prospective pilot case- control study from a single cancer center. Mediterr J Hematol Infect Dis. 2015; 7(1):e2015032. PMID: 25960860; PMCID: PMC4418373.
    13. Le J, Ny P, Capparelli E, Lane J, Ngu B, Muus R, Romanowski G, Vo T, Bradley J. Pharmacodynamic Characteristics of Nephrotoxicity Associated With Vancomycin Use in Children. J Pediatric Infect Dis Soc. 2015 Dec; 4(4):e109-16. PMID: 26582878.
      View in: PubMed
    14. Le J, Gales MA, Gales BJ. Acetaminophen for patent ductus arteriosus. Ann Pharmacother. 2015 Feb; 49(2):241-6. PMID: 25352038.
      View in: PubMed
    15. Le J, Ngu B, Bradley JS, Murray W, Nguyen A, Nguyen L, Romanowski GL, Vo T, Capparelli EV. Vancomycin monitoring in children using bayesian estimation. Ther Drug Monit. 2014 Aug; 36(4):510-8. PMID: 24452067; PMCID: PMC4101060.
    16. Jackevicius CA, Le J, Nazer L, Hess K, Wang J, Law AV. A formal mentorship program for faculty development. Am J Pharm Educ. 2014 Jun 17; 78(5):100. PMID: 24954940; PMCID: PMC4064477.
    17. Tremoulet A, Le J, Poindexter B, Sullivan JE, Laughon M, Delmore P, Salgado A, Ian-U Chong S, Melloni C, Gao J, Benjamin DK, Capparelli EV, Cohen-Wolkowiez M. Characterization of the population pharmacokinetics of ampicillin in neonates using an opportunistic study design. Antimicrob Agents Chemother. 2014 Jun; 58(6):3013-20. PMID: 24614374.
      View in: PubMed
    18. Le J, Vaida F, Nguyen E, Adler-Shohet FC, Romanowski G, Kim J, Vo T, Capparelli EV. Population-Based Pharmacokinetic Modeling of Vancomycin in Children with Renal Insufficiency. J Pharmacol Clin Toxicol. 2014; 2(1):1017-1026. PMID: 25309945.
      View in: PubMed
    19. Le J, Bradley JS, Murray W, Romanowski GL, Tran TT, Nguyen N, Cho S, Natale S, Bui I, Tran TM, Capparelli EV. Improved vancomycin dosing in children using area under the curve exposure. Pediatr Infect Dis J. 2013 Apr; 32(4):e155-63. PMID: 23340565; PMCID: PMC3632448.
    20. Le J, Tran TT, Bui I, Wang MK, Vo A, Adler-Shohet FC. Time to initiation of antifungal therapy for neonatal candidiasis. Antimicrob Agents Chemother. 2013 Jun; 57(6):2550-5. PMID: 23507285; PMCID: PMC3716169.
    21. Hill SE, Iqbal R, Cadiz CL, Le J. Foodborne botulism treated with heptavalent botulism antitoxin. Ann Pharmacother. 2013 Feb; 47(2):e12. PMID: 23362041.
      View in: PubMed
    22. Le J, McKee B, Srisupha-Olarn W, Burgess DS. In vitro activity of carbapenems alone and in combination with amikacin against KPC-producing Klebsiella pneumoniae. J Clin Med Res. 2011 May 19; 3(3):106-10. PMID: 21811540; PMCID: PMC3138406.
    23. McKamy S, Hernandez E, Jahng M, Moriwaki T, Deveikis A, Le J. Incidence and risk factors influencing the development of vancomycin nephrotoxicity in children. J Pediatr. 2011 Mar; 158(3):422-6. PMID: 20888013.
      View in: PubMed
    24. Le J, Bookstaver PB, Rudisill CN, Hashem MG, Iqbal R, James CL, Sakoulas G. Treatment of meningitis caused by vancomycin-resistant Enterococcus faecium: high-dose and combination daptomycin therapy. Ann Pharmacother. 2010 Dec; 44(12):2001-6. PMID: 21119097.
      View in: PubMed
    25. Le J, San Agustin M, Hernandez EA, Tran TT, Adler-Shohet FC. Complications associated with outpatient parenteral antibiotic therapy in children. Clin Pediatr (Phila). 2010 Nov; 49(11):1038-43. PMID: 20724346.
      View in: PubMed
    26. Le J, Ashley ED, Neuhauser MM, Brown J, Gentry C, Klepser ME, Marr AM, Schiller D, Schwiesow JN, Tice S, VandenBussche HL, Wood GC. Consensus summary of aerosolized antimicrobial agents: application of guideline criteria. Insights from the Society of Infectious Diseases Pharmacists. Pharmacotherapy. 2010 Jun; 30(6):562-84. PMID: 20500046.
      View in: PubMed
    27. Le J, Schiller DS. Aerosolized Delivery of Antifungal Agents. Curr Fungal Infect Rep. 2010 Jun; 4(2):96-102. PMID: 20502511.
      View in: PubMed
    28. Le J, Castanheira M, Burgess DS, McKee B, Iqbal R, Jones RN. Clonal dissemination of Klebsiella pneumoniae carbapenemase KPC-3 in Long Beach, California. J Clin Microbiol. 2010 Feb; 48(2):623-5. PMID: 20032252; PMCID: PMC2815646.
    29. Le J, Adler-Shohet FC, Nguyen C, Lieberman JM. Nephrotoxicity associated with amphotericin B deoxycholate in neonates. Pediatr Infect Dis J. 2009 Dec; 28(12):1061-3. PMID: 19935267.
      View in: PubMed
    30. Le J, Nguyen T, Okamoto M, McKamy S, Lieberman JM. Impact of empiric antibiotic use on development of infections caused by extended-spectrum beta-lactamase bacteria in a neonatal intensive care unit. Pediatr Infect Dis J. 2008 Apr; 27(4):314-8. PMID: 18316990.
      View in: PubMed
    31. Le J, Lieberman JM. Management of community-associated methicillin-resistant Staphylococcus aureus infections in children. Pharmacotherapy. 2006 Dec; 26(12):1758-70. PMID: 17125437.
      View in: PubMed
    32. Le J, Nguyen T, Law AV, Hodding J. Adverse drug reactions among children over a 10-year period. Pediatrics. 2006 Aug; 118(2):555-62. PMID: 16882807.
      View in: PubMed
    33. Le J, Briggs GG, McKeown A, Bustillo G. Urinary tract infections during pregnancy. Ann Pharmacother. 2004 Oct; 38(10):1692-701. PMID: 15340129.
      View in: PubMed