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Lori Broderick

Title(s)Assistant Adjunct Professor, Pediatrics
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #0760
La Jolla CA 92093
Phone8/5-34--1703
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    Collapse Research 
    Collapse Research Activities and Funding
    Molecular Genetics and Immunoregulatory mechanisms of PFAPA syndrome
    NIH/NICHD K08HD075830May 1, 2014 - Apr 30, 2019
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Immune Dysregulation in the Tonsillar Microenvironment of Periodic Fever, Aphthous Stomatitis, Pharyngitis, Adenitis (PFAPA) Syndrome. J Clin Immunol. 2020 01; 40(1):179-190. Luu I, Sharma A, Guaderrama M, Peru M, Nation J, Page N, Carvalho D, Magit A, Jiang W, Leuin S, Bliss M, Bothwell M, Brigger M, Kearns D, Newbury R, Pransky S, Gilbert JA, Broderick L. PMID: 31807979.
      View in: PubMed   Mentions:    Fields:    
    2. Mutations in topoisomerase IIß result in a B cell immunodeficiency. Nat Commun. 2019 08 13; 10(1):3644. Broderick L, Yost S, Li D, McGeough MD, Booshehri LM, Guaderrama M, Brydges SD, Kucharova K, Patel NC, Harr M, Hakonarson H, Zackai E, Cowell IG, Austin CA, Hügle B, Gebauer C, Zhang J, Xu X, Wang J, Croker BA, Frazer KA, Putnam CD, Hoffman HM. PMID: 31409799.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    3. Hereditary Autoinflammatory Disorders: Recognition and Treatment. Immunol Allergy Clin North Am. 2019 02; 39(1):13-29. Broderick L. PMID: 30466770.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    4. TNF regulates transcription of NLRP3 inflammasome components and inflammatory molecules in cryopyrinopathies. J Clin Invest. 2017 12 01; 127(12):4488-4497. McGeough MD, Wree A, Inzaugarat ME, Haimovich A, Johnson CD, Peña CA, Goldbach-Mansky R, Broderick L, Feldstein AE, Hoffman HM. PMID: 29130929.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    5. Novel mutation identified in severe early-onset tumor necrosis factor receptor-associated periodic syndrome: a case report. BMC Pediatr. 2017 04 20; 17(1):108. Radhakrishna SM, Grimm A, Broderick L. PMID: 28427379.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Editorial: It Just Takes One: Somatic Mosaicism in Autoinflammatory Disease. Arthritis Rheumatol. 2017 02; 69(2):253-256. Hoffman HM, Broderick L. PMID: 27748054.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    7. The role of the inflammasome in patients with autoinflammatory diseases. J Allergy Clin Immunol. 2016 07; 138(1):3-14. Hoffman HM, Broderick L. PMID: 27373321.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    8. Recurrent Fevers for the Pediatric Immunologist: It's Not All Immunodeficiency. Curr Allergy Asthma Rep. 2016 Jan; 16(1):2. Broderick L. PMID: 26707379.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    9. NLRP3 mediates osteolysis through inflammation-dependent and -independent mechanisms. FASEB J. 2015 Apr; 29(4):1269-79. Qu C, Bonar SL, Hickman-Brecks CL, Abu-Amer S, McGeough MD, Peña CA, Broderick L, Yang C, Grimston SK, Kading J, Abu-Amer Y, Novack DV, Hoffman HM, Civitelli R, Mbalaviele G. PMID: 25477279.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    10. cASCading specks. Nat Immunol. 2014 Aug; 15(8):698-700. Broderick L, Hoffman HM. PMID: 25045869.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    11. From NAFLD to NASH to cirrhosis-new insights into disease mechanisms. Nat Rev Gastroenterol Hepatol. 2013 Nov; 10(11):627-36. Wree A, Broderick L, Canbay A, Hoffman HM, Feldstein AE. PMID: 23958599.
      View in: PubMed   Mentions: 130     Fields:    Translation:Humans
    12. Mutations of complement factor I and potential mechanisms of neuroinflammation in acute hemorrhagic leukoencephalitis. J Clin Immunol. 2013 Jan; 33(1):162-71. Broderick L, Gandhi C, Mueller JL, Putnam CD, Shayan K, Giclas PC, Peterson KS, Aceves SS, Sheets RM, Peterson BM, Newbury RO, Hoffman HM, Bastian JF. PMID: 22926405.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    13. Cutting edge: IL-6 is a marker of inflammation with no direct role in inflammasome-mediated mouse models. J Immunol. 2012 Sep 15; 189(6):2707-11. McGeough MD, Pena CA, Mueller JL, Pociask DA, Broderick L, Hoffman HM, Brydges SD. PMID: 22904305.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    14. Prolonged urticaria and fever in a toddler. Allergy Asthma Proc. 2012 May-Jun; 33(3):297-301. Broderick L, Tremoulet AH, Burns JC, Hoffman HM. PMID: 22584197.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    15. Biologic modulators in allergic and autoinflammatory diseases. Curr Opin Allergy Clin Immunol. 2011 Aug; 11(4):355-60. Broderick L, Tourangeau LM, Kavanaugh A, Wasserman SI. PMID: 21659854.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    16. Recurrent fever syndromes in patients after recovery from Kawasaki syndrome. Pediatrics. 2011 Feb; 127(2):e489-93. Broderick L, Tremoulet AH, Burns JC, Bastian JF, Hoffman HM. PMID: 21220401.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans