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    Volker Vallon

    TitleProfessor
    SchoolUniversity of California, San Diego
    DepartmentMedicine
    Address9500 Gilman Drive #9151
    CA La Jolla 92093
    Phone858-552-8585
    vCardDownload vCard

      Collapse Overview 

      Collapse Research 
      Collapse Research Activities and Funding
      Glomerular and Tubular Function in the Diabetic Kidney
      NIH/NIDDK R01DK112042Jul 1, 2017 - Apr 30, 2022
      Role: Co-Principal Investigator
      Blood Pressure Regulation by OAT3
      NIH/NHLBI R01HL094728Jun 1, 2010 - Apr 30, 2015
      Role: Principal Investigator

      Collapse ORNG Applications 
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      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Vallon V, Thomson SC. Diabetes mellitus: Cardiovascular and renal benefits of SGLT2 inhibition: insights from CANVAS. Nat Rev Nephrol. 2017 Sep; 13(9):517-518. PMID: 28781373.
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      2. Layton AT, Edwards A, Vallon V. Adaptive changes in GFR, tubular morphology, and transport in subtotal nephrectomized kidneys: modeling and analysis. Am J Physiol Renal Physiol. 2017 Aug 01; 313(2):F199-F209. PMID: 28331059.
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      3. Hallow KM, Gebremichael Y, Helmlinger G, Vallon V. Primary proximal tubule hyperreabsorption and impaired tubular transport counterregulation determine glomerular hyperfiltration in diabetes: a modeling analysis. Am J Physiol Renal Physiol. 2017 Feb 01; ajprenal.00497.2016. PMID: 28148531.
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      4. Qiu H, Novikov A, Vallon V. Ketosis and Diabetic Ketoacidosis in Response to SGLT2 Inhibitors: Basic Mechanisms and Therapeutic Perspectives. Diabetes Metab Res Rev. 2017 Jan 18. PMID: 28099783.
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      5. Vallon V, Thomson SC. Targeting renal glucose reabsorption to treat hyperglycaemia: the pleiotropic effects of SGLT2 inhibition. Diabetologia. 2016 Nov 22. PMID: 27878313.
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      6. Layton AT, Vallon V, Edwards A. A Computational Model for Simulating Solute Transport and Oxygen Consumption along the Nephrons. Am J Physiol Renal Physiol. 2016 Oct 5; ajprenal.00293.2016. PMID: 27707705.
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      7. Layton AT, Laghmani K, Vallon V, Edwards A. Solute Transport and Oxygen Consumption along the Nephrons: Effects of Na+ Transport Inhibitors. Am J Physiol Renal Physiol. 2016 Oct 5; ajprenal.00294.2016. PMID: 27707706.
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      8. Yang L, Frindt G, Lang F, Kuhl D, Vallon V, Palmer LG. SGK1-dependent ENaC processing and trafficking in mice with high dietary K intake and elevated aldosterone. Am J Physiol Renal Physiol. 2017 Jan 01; 312(1):F65-F76. PMID: 27413200.
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      9. Gallo LA, Ward MS, Fotheringham AK, Zhuang A, Borg DJ, Flemming NB, Harvie BM, Kinneally TL, Yeh SM, McCarthy DA, Koepsell H, Vallon V, Pollock C, Panchapakesan U, Forbes JM. Erratum: Once daily administration of the SGLT2 inhibitor, empagliflozin, attenuates markers of renal fibrosis without improving albuminuria in diabetic db/db mice. Sci Rep. 2016; 6:28124. PMID: 27389496.
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      10. Vallon V. Tubular Transport in Acute Kidney Injury: Relevance for Diagnosis, Prognosis and Intervention. Nephron. 2016; 134(3):160-166. PMID: 27238156.
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      11. Gallo LA, Ward MS, Fotheringham AK, Zhuang A, Borg DJ, Flemming NB, Harvie BM, Kinneally TL, Yeh SM, McCarthy DA, Koepsell H, Vallon V, Pollock C, Panchapakesan U, Forbes JM. Once daily administration of the SGLT2 inhibitor, empagliflozin, attenuates markers of renal fibrosis without improving albuminuria in diabetic db/db mice. Sci Rep. 2016; 6:26428. PMID: 27226136.
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      12. Song P, Onishi A, Koepsell H, Vallon V. Sodium glucose cotransporter SGLT1 as a therapeutic target in diabetes mellitus. Expert Opin Ther Targets. 2016 Sep; 20(9):1109-25. PMID: 26998950.
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      13. Layton AT, Vallon V, Edwards A. Predicted consequences of diabetes and SGLT inhibition on transport and oxygen consumption along a rat nephron. Am J Physiol Renal Physiol. 2016 Jun 1; 310(11):F1269-83. PMID: 26764207.
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      14. Novikov A, Vallon V. Sodium glucose cotransporter 2 inhibition in the diabetic kidney: an update. Curr Opin Nephrol Hypertens. 2016 Jan; 25(1):50-8. PMID: 26575393.
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      15. Michel MC, Mayoux E, Vallon V. A comprehensive review of the pharmacodynamics of the SGLT2 inhibitor empagliflozin in animals and humans. Naunyn Schmiedebergs Arch Pharmacol. 2015 Aug; 388(8):801-16. PMID: 26108304.
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      16. Layton AT, Vallon V, Edwards A. Modeling oxygen consumption in the proximal tubule: effects of NHE and SGLT2 inhibition. Am J Physiol Renal Physiol. 2015 Jun 15; 308(12):F1343-57. PMID: 25855513.
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      17. Gallo LA, Wright EM, Vallon V. Probing SGLT2 as a therapeutic target for diabetes: Basic physiology and consequences. Diab Vasc Dis Res. 2015 Mar; 12(2):78-89. PMID: 25616707.
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      18. Fu Y, Gerasimova M, Batz F, Kuczkowski A, Alam Y, Sanders PW, Ronzaud C, Hummler E, Vallon V. PPAR? Agonist-Induced Fluid Retention Depends on aENaC Expression in Connecting Tubules. Nephron Physiol. 2015; 129(1):68-74. PMID: 25531136.
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      19. Fu Y, Vallon V. Mineralocorticoid-induced sodium appetite and renal salt retention: evidence for common signaling and effector mechanisms. Nephron Physiol. 2014; 128(1-2):8-16. PMID: 25376899.
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      20. Xie R, Dong X, Wong C, Vallon V, Tang B, Sun J, Yang S, Dong H. Molecular Mechanisms of Calcium-sensing Receptor-mediated Calcium Signaling in the Modulation of Epithelial Ion Transport and Bicarbonate Secretion. J Biol Chem. 2014 Dec 12; 289(50):34642-53. PMID: 25331955.
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      21. Vallon V. The Mechanisms and Therapeutic Potential of SGLT2 Inhibitors in Diabetes Mellitus. Annu Rev Med. 2015 Jan 14; 66:255-70. PMID: 25341005.
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      22. Vallon V. Do tubular changes in the diabetic kidney affect the susceptibility to acute kidney injury? Nephron Clin Pract. 2014; 127(1-4):133-8. PMID: 25343837.
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      23. Vallon V, Docherty NG. Intestinal regulation of urinary sodium excretion and the pathophysiology of diabetic kidney disease: a focus on glucagon-like peptide 1 and dipeptidyl peptidase 4. Exp Physiol. 2014 Sep 1; 99(9):1140-5. PMID: 25085841.
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      24. Kumar R, Vallon V. Reduced renal calcium excretion in the absence of sclerostin expression: evidence for a novel calcium-regulating bone kidney axis. J Am Soc Nephrol. 2014 Oct; 25(10):2159-68. PMID: 24876121.
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      25. Edwards A, Castrop H, Laghmani K, Vallon V, Layton AT. Effects of NKCC2 isoform regulation on NaCl transport in thick ascending limb and macula densa: a modeling study. Am J Physiol Renal Physiol. 2014 Jul 15; 307(2):F137-46. PMID: 24848496.
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      26. Borsting E, Patel SV, Declèves AE, Lee SJ, Rahman QM, Akira S, Satriano J, Sharma K, Vallon V, Cunard R. Tribbles homolog 3 attenuates Mammalian target of rapamycin complex-2 signaling and inflammation in the diabetic kidney. J Am Soc Nephrol. 2014 Sep; 25(9):2067-78. PMID: 24676635.
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      27. Gailly P, Szutkowska M, Olinger E, Debaix H, Seghers F, Janas S, Vallon V, Devuyst O. P2Y2 receptor activation inhibits the expression of the sodium-chloride cotransporter NCC in distal convoluted tubule cells. Pflugers Arch. 2014 Nov; 466(11):2035-47. PMID: 24463702.
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      28. Masuda T, Fu Y, Eguchi A, Czogalla J, Rose MA, Kuczkowski A, Gerasimova M, Feldstein AE, Scadeng M, Vallon V. Dipeptidyl peptidase IV inhibitor lowers PPAR? agonist-induced body weight gain by affecting food intake, fat mass, and beige/brown fat but not fluid retention. Am J Physiol Endocrinol Metab. 2014 Feb; 306(4):E388-98. PMID: 24347054.
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      29. Rieg T, Masuda T, Gerasimova M, Mayoux E, Platt K, Powell DR, Thomson SC, Koepsell H, Vallon V. Increase in SGLT1-mediated transport explains renal glucose reabsorption during genetic and pharmacological SGLT2 inhibition in euglycemia. Am J Physiol Renal Physiol. 2014 Jan; 306(2):F188-93. PMID: 24226519.
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      30. Vallon V, Gerasimova M, Rose MA, Masuda T, Satriano J, Mayoux E, Koepsell H, Thomson SC, Rieg T. SGLT2 inhibitor empagliflozin reduces renal growth and albuminuria in proportion to hyperglycemia and prevents glomerular hyperfiltration in diabetic Akita mice. Am J Physiol Renal Physiol. 2014 Jan; 306(2):F194-204. PMID: 24226524.
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      31. Vallon V, Rose M, Gerasimova M, Satriano J, Platt KA, Koepsell H, Cunard R, Sharma K, Thomson SC, Rieg T. Knockout of Na-glucose transporter SGLT2 attenuates hyperglycemia and glomerular hyperfiltration but not kidney growth or injury in diabetes mellitus. Am J Physiol Renal Physiol. 2013 Jan 15; 304(2):F156-67. PMID: 23152292.
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      32. Rieg T, Tang T, Uchida S, Hammond HK, Fenton RA, Vallon V. Adenylyl cyclase 6 enhances NKCC2 expression and mediates vasopressin-induced phosphorylation of NKCC2 and NCC. Am J Pathol. 2013 Jan; 182(1):96-106. PMID: 23123217.
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      33. Stockand JD, Vallon V, Ortiz P. In vivo and ex vivo analysis of tubule function. Compr Physiol. 2012 Oct; 2(4):2495-525. PMID: 23720256.
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      34. Vallon V, Stockand J, Rieg T. P2Y receptors and kidney function. Wiley Interdiscip Rev Membr Transp Signal. 2012; 1(6):731-742. PMID: 23145369.
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      35. Rieg T, Gerasimova M, Murray F, Masuda T, Tang T, Rose M, Drucker DJ, Vallon V. Natriuretic effect by exendin-4, but not the DPP-4 inhibitor alogliptin, is mediated via the GLP-1 receptor and preserved in obese type 2 diabetic mice. Am J Physiol Renal Physiol. 2012 Oct; 303(7):F963-71. PMID: 22832924.
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      36. Blantz RC, Singh P, Deng A, Thomson SC, Vallon V. Acute saline expansion increases nephron filtration and distal flow rate but maintains tubuloglomerular feedback responsiveness: role of adenosine A(1) receptors. Am J Physiol Renal Physiol. 2012 Aug 1; 303(3):F405-11. PMID: 22622464.
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      37. Vallon V, Eraly SA, Rao SR, Gerasimova M, Rose M, Nagle M, Anzai N, Smith T, Sharma K, Nigam SK, Rieg T. A role for the organic anion transporter OAT3 in renal creatinine secretion in mice. Am J Physiol Renal Physiol. 2012 May 15; 302(10):F1293-9. PMID: 22338083.
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      38. Sabolic I, Vrhovac I, Eror DB, Gerasimova M, Rose M, Breljak D, Ljubojevic M, Brzica H, Sebastiani A, Thal SC, Sauvant C, Kipp H, Vallon V, Koepsell H. Expression of Na+-D-glucose cotransporter SGLT2 in rodents is kidney-specific and exhibits sex and species differences. Am J Physiol Cell Physiol. 2012 Apr 15; 302(8):C1174-88. PMID: 22262063.
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      39. Vallon V, Thomson SC. Renal function in diabetic disease models: the tubular system in the pathophysiology of the diabetic kidney. Annu Rev Physiol. 2012; 74:351-75. PMID: 22335797.
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      40. Toney GM, Vallon V, Stockand JD. Intrinsic control of sodium excretion in the distal nephron by inhibitory purinergic regulation of the epithelial Na(+) channel. Curr Opin Nephrol Hypertens. 2012 Jan; 21(1):52-60. PMID: 22143248.
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      41. Borsting E, Cheng VP, Glass CK, Vallon V, Cunard R. Peroxisome proliferator-activated receptor-? agonists repress epithelial sodium channel expression in the kidney. Am J Physiol Renal Physiol. 2012 Mar 1; 302(5):F540-51. PMID: 22169011.
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      42. Gorboulev V, Schürmann A, Vallon V, Kipp H, Jaschke A, Klessen D, Friedrich A, Scherneck S, Rieg T, Cunard R, Veyhl-Wichmann M, Srinivasan A, Balen D, Breljak D, Rexhepaj R, Parker HE, Gribble FM, Reimann F, Lang F, Wiese S, Sabolic I, Sendtner M, Koepsell H. Na(+)-D-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion. Diabetes. 2012 Jan; 61(1):187-96. PMID: 22124465.
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      43. Lang F, Vallon V. Serum- and glucocorticoid-inducible kinase 1 in the regulation of renal and extrarenal potassium transport. Clin Exp Nephrol. 2012 Feb; 16(1):73-80. PMID: 22038256.
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      44. Thomson SC, Rieg T, Miracle C, Mansoury H, Whaley J, Vallon V, Singh P. Acute and chronic effects of SGLT2 blockade on glomerular and tubular function in the early diabetic rat. Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1; 302(1):R75-83. PMID: 21940401.
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      45. Vallon V, Komers R. Pathophysiology of the diabetic kidney. Compr Physiol. 2011 Jul; 1(3):1175-232. PMID: 23733640.
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      46. Vallon V, Rieg T. Regulation of renal NaCl and water transport by the ATP/UTP/P2Y2 receptor system. Am J Physiol Renal Physiol. 2011 Sep; 301(3):F463-75. PMID: 21715471.
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      47. Vallon V, Thomson SC. Anomalous role for dietary salt in diabetes mellitus? Nat Rev Endocrinol. 2011 Jul; 7(7):377-8. PMID: 21629234.
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      48. Horikawa YT, Panneerselvam M, Kawaraguchi Y, Tsutsumi YM, Ali SS, Balijepalli RC, Murray F, Head BP, Niesman IR, Rieg T, Vallon V, Insel PA, Patel HH, Roth DM. Cardiac-specific overexpression of caveolin-3 attenuates cardiac hypertrophy and increases natriuretic peptide expression and signaling. J Am Coll Cardiol. 2011 May 31; 57(22):2273-83. PMID: 21616289.
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      49. Tuo B, Wen G, Wei J, Liu X, Wang X, Zhang Y, Wu H, Dong X, Chow JY, Vallon V, Dong H. Estrogen regulation of duodenal bicarbonate secretion and sex-specific protection of human duodenum. Gastroenterology. 2011 Sep; 141(3):854-63. PMID: 21699784.
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      50. Rieg T, Gerasimova M, Boyer JL, Insel PA, Vallon V. P2Y2 receptor activation decreases blood pressure and increases renal Na? excretion. Am J Physiol Regul Integr Comp Physiol. 2011 Aug; 301(2):R510-8. PMID: 21613580.
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      51. Sweeney DE, Vallon V, Rieg T, Wu W, Gallegos TF, Nigam SK. Functional maturation of drug transporters in the developing, neonatal, and postnatal kidney. Mol Pharmacol. 2011 Jul; 80(1):147-54. PMID: 21493727.
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      52. Vallon V. The proximal tubule in the pathophysiology of the diabetic kidney. Am J Physiol Regul Integr Comp Physiol. 2011 May; 300(5):R1009-22. PMID: 21228342.
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      53. Vallon V. Molecular determinants of renal glucose reabsorption. Focus on "Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2". Am J Physiol Cell Physiol. 2011 Jan; 300(1):C6-8. PMID: 21048164.
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      54. Lang F, Huang DY, Vallon V. SGK, renal function and hypertension. J Nephrol. 2010 Nov-Dec; 23 Suppl 16:S124-9. PMID: 21170869.
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      55. Rieg T, Tang T, Murray F, Schroth J, Insel PA, Fenton RA, Hammond HK, Vallon V. Adenylate cyclase 6 determines cAMP formation and aquaporin-2 phosphorylation and trafficking in inner medulla. J Am Soc Nephrol. 2010 Dec; 21(12):2059-68. PMID: 20864687.
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      56. Stockand JD, Mironova E, Bugaj V, Rieg T, Insel PA, Vallon V, Peti-Peterdi J, Pochynyuk O. Purinergic inhibition of ENaC produces aldosterone escape. J Am Soc Nephrol. 2010 Nov; 21(11):1903-11. PMID: 20813869.
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      57. Vallon V, Sharma K. Sodium-glucose transport: role in diabetes mellitus and potential clinical implications. Curr Opin Nephrol Hypertens. 2010 Sep; 19(5):425-31. PMID: 20539226.
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      58. Morse E, Schroth J, You YH, Pizzo DP, Okada S, Ramachandrarao S, Vallon V, Sharma K, Cunard R. TRB3 is stimulated in diabetic kidneys, regulated by the ER stress marker CHOP, and is a suppressor of podocyte MCP-1. Am J Physiol Renal Physiol. 2010 Nov; 299(5):F965-72. PMID: 20660016.
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      59. Vallon V, Platt KA, Cunard R, Schroth J, Whaley J, Thomson SC, Koepsell H, Rieg T. SGLT2 mediates glucose reabsorption in the early proximal tubule. J Am Soc Nephrol. 2011 Jan; 22(1):104-12. PMID: 20616166.
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      60. Satriano J, Mansoury H, Deng A, Sharma K, Vallon V, Blantz RC, Thomson SC. Transition of kidney tubule cells to a senescent phenotype in early experimental diabetes. Am J Physiol Cell Physiol. 2010 Aug; 299(2):C374-80. PMID: 20505038.
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      61. Pochynyuk O, Rieg T, Bugaj V, Schroth J, Fridman A, Boss GR, Insel PA, Stockand JD, Vallon V. Dietary Na+ inhibits the open probability of the epithelial sodium channel in the kidney by enhancing apical P2Y2-receptor tone. FASEB J. 2010 Jun; 24(6):2056-65. PMID: 20097874.
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      62. Lang F, Görlach A, Vallon V. Targeting SGK1 in diabetes. Expert Opin Ther Targets. 2009 Nov; 13(11):1303-11. PMID: 19764891.
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      63. Lang F, Artunc F, Vallon V. The physiological impact of the serum and glucocorticoid-inducible kinase SGK1. Curr Opin Nephrol Hypertens. 2009 Sep; 18(5):439-48. PMID: 19584721.
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      64. Vallon V, Schroth J, Lang F, Kuhl D, Uchida S. Expression and phosphorylation of the Na+-Cl- cotransporter NCC in vivo is regulated by dietary salt, potassium, and SGK1. Am J Physiol Renal Physiol. 2009 Sep; 297(3):F704-12. PMID: 19570885.
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      65. Wu W, Kitamura S, Truong DM, Rieg T, Vallon V, Sakurai H, Bush KT, Vera DR, Ross RS, Nigam SK. Beta1-integrin is required for kidney collecting duct morphogenesis and maintenance of renal function. Am J Physiol Renal Physiol. 2009 Jul; 297(1):F210-7. PMID: 19439520.
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      66. Boini KM, Graf D, Hennige AM, Koka S, Kempe DS, Wang K, Ackermann TF, Föller M, Vallon V, Pfeifer K, Schleicher E, Ullrich S, Häring HU, Häussinger D, Lang F. Enhanced insulin sensitivity of gene-targeted mice lacking functional KCNQ1. Am J Physiol Regul Integr Comp Physiol. 2009 Jun; 296(6):R1695-701. PMID: 19369585.
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      67. Vallon V, Schroth J, Satriano J, Blantz RC, Thomson SC, Rieg T. Adenosine A(1) receptors determine glomerular hyperfiltration and the salt paradox in early streptozotocin diabetes mellitus. Nephron Physiol. 2009; 111(3):p30-8. PMID: 19276628.
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      68. Ackermann TF, Boini KM, Völkl H, Bhandaru M, Bareiss PM, Just L, Vallon V, Amann K, Kuhl D, Feng Y, Hammes HP, Lang F. SGK1-sensitive renal tubular glucose reabsorption in diabetes. Am J Physiol Renal Physiol. 2009 Apr; 296(4):F859-66. PMID: 19158347.
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      69. Vallon V, Hummler E, Rieg T, Pochynyuk O, Bugaj V, Schroth J, Dechenes G, Rossier B, Cunard R, Stockand J. Thiazolidinedione-induced fluid retention is independent of collecting duct alphaENaC activity. J Am Soc Nephrol. 2009 Apr; 20(4):721-9. PMID: 19158355.
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      70. Vallon V, Osswald H. Adenosine receptors and the kidney. Handb Exp Pharmacol. 2009; (193):443-70. PMID: 19639291.
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      71. Vallon V. Regulation of the Na+-Cl- cotransporter by dietary NaCl: a role for WNKs, SPAK, OSR1, and aldosterone. Kidney Int. 2008 Dec; 74(11):1373-5. PMID: 19008908.
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      72. Rieg T, Vallon V. ATP and adenosine in the local regulation of water transport and homeostasis by the kidney. Am J Physiol Regul Integr Comp Physiol. 2009 Feb; 296(2):R419-27. PMID: 19020292.
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      73. Pochynyuk O, Bugaj V, Rieg T, Insel PA, Mironova E, Vallon V, Stockand JD. Paracrine regulation of the epithelial Na+ channel in the mammalian collecting duct by purinergic P2Y2 receptor tone. J Biol Chem. 2008 Dec 26; 283(52):36599-607. PMID: 18981175.
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      74. Vallon V. Micropuncturing the nephron. Pflugers Arch. 2009 May; 458(1):189-201. PMID: 18752000.
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      75. Miracle CM, Rieg T, Mansoury H, Vallon V, Thomson SC. Ornithine decarboxylase inhibitor eliminates hyperresponsiveness of the early diabetic proximal tubule to dietary salt. Am J Physiol Renal Physiol. 2008 Oct; 295(4):F995-F1002. PMID: 18562630.
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      76. Vallon V, Eraly SA, Wikoff WR, Rieg T, Kaler G, Truong DM, Ahn SY, Mahapatra NR, Mahata SK, Gangoiti JA, Wu W, Barshop BA, Siuzdak G, Nigam SK. Organic anion transporter 3 contributes to the regulation of blood pressure. J Am Soc Nephrol. 2008 Sep; 19(9):1732-40. PMID: 18508962.
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      77. Laske-Ernst J, Stehle A, Vallon V, Quast U, Russ U. Effect of adenosine on membrane potential and Ca2+ in juxtaglomerular cells. Comparison with angiotensin II. Kidney Blood Press Res. 2008; 31(2):94-103. PMID: 18322364.
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      78. Eraly SA, Vallon V, Rieg T, Gangoiti JA, Wikoff WR, Siuzdak G, Barshop BA, Nigam SK. Multiple organic anion transporters contribute to net renal excretion of uric acid. Physiol Genomics. 2008 Apr 22; 33(2):180-92. PMID: 18270321.
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      79. Vallon V, Miracle C, Thomson S. Adenosine and kidney function: potential implications in patients with heart failure. Eur J Heart Fail. 2008 Feb; 10(2):176-87. PMID: 18242127.
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      80. Vallon V, Rieg T, Ahn SY, Wu W, Eraly SA, Nigam SK. Overlapping in vitro and in vivo specificities of the organic anion transporters OAT1 and OAT3 for loop and thiazide diuretics. Am J Physiol Renal Physiol. 2008 Apr; 294(4):F867-73. PMID: 18216144.
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      81. Rieg T, Pothula K, Schroth J, Satriano J, Osswald H, Schnermann J, Insel PA, Bundey RA, Vallon V. Vasopressin regulation of inner medullary collecting ducts and compensatory changes in mice lacking adenosine A1 receptors. Am J Physiol Renal Physiol. 2008 Mar; 294(3):F638-44. PMID: 18199602.
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      82. Vallon V. P2 receptors in the regulation of renal transport mechanisms. Am J Physiol Renal Physiol. 2008 Jan; 294(1):F10-27. PMID: 17977905.
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      83. Miracle CM, Rieg T, Blantz RC, Vallon V, Thomson SC. Combined effects of carbonic anhydrase inhibitor and adenosine A1 receptor antagonist on hemodynamic and tubular function in the kidney. Kidney Blood Press Res. 2007; 30(6):388-99. PMID: 17890869.
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      84. Grenz A, Zhang H, Weingart J, von Wietersheim S, Eckle T, Schnermann J, Köhle C, Kloor D, Gleiter CH, Vallon V, Eltzschig HK, Osswald H. Lack of effect of extracellular adenosine generation and signaling on renal erythropoietin secretion during hypoxia. Am J Physiol Renal Physiol. 2007 Nov; 293(5):F1501-11. PMID: 17855480.
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      85. Lang F, Vallon V, Knipper M, Wangemann P. Functional significance of channels and transporters expressed in the inner ear and kidney. Am J Physiol Cell Physiol. 2007 Oct; 293(4):C1187-208. PMID: 17670895.
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      86. Rieg T, Vallon V, Sausbier M, Sausbier U, Kaissling B, Ruth P, Osswald H. The role of the BK channel in potassium homeostasis and flow-induced renal potassium excretion. Kidney Int. 2007 Sep; 72(5):566-73. PMID: 17579662.
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      87. Rieg T, Bundey RA, Chen Y, Deschenes G, Junger W, Insel PA, Vallon V. Mice lacking P2Y2 receptors have salt-resistant hypertension and facilitated renal Na+ and water reabsorption. FASEB J. 2007 Nov; 21(13):3717-26. PMID: 17575258.
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      88. Blantz RC, Vallon V. Tubuloglomerular feedback responses of the downstream efferent resistance: unmasking a role for adenosine? Kidney Int. 2007 May; 71(9):837-9. PMID: 17457327.
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      89. Zhang W, Xia X, Reisenauer MR, Rieg T, Lang F, Kuhl D, Vallon V, Kone BC. Aldosterone-induced Sgk1 relieves Dot1a-Af9-mediated transcriptional repression of epithelial Na+ channel alpha. J Clin Invest. 2007 Mar; 117(3):773-83. PMID: 17332896.
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      90. Rieg T, Schnermann J, Vallon V. Adenosine A1 receptors determine effects of caffeine on total fluid intake but not caffeine appetite. Eur J Pharmacol. 2007 Jan 26; 555(2-3):174-7. PMID: 17126319.
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      91. Lang F, Böhmer C, Palmada M, Seebohm G, Strutz-Seebohm N, Vallon V. (Patho)physiological significance of the serum- and glucocorticoid-inducible kinase isoforms. Physiol Rev. 2006 Oct; 86(4):1151-78. PMID: 17015487.
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      92. Huang DY, Boini KM, Osswald H, Friedrich B, Artunc F, Ullrich S, Rajamanickam J, Palmada M, Wulff P, Kuhl D, Vallon V, Lang F. Resistance of mice lacking the serum- and glucocorticoid-inducible kinase SGK1 against salt-sensitive hypertension induced by a high-fat diet. Am J Physiol Renal Physiol. 2006 Dec; 291(6):F1264-73. PMID: 17003223.
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      93. Artunc F, Amann K, Nasir O, Friedrich B, Sandulache D, Jahovic N, Risler T, Vallon V, Wulff P, Kuhl D, Lang F. Blunted DOCA/high salt induced albuminuria and renal tubulointerstitial damage in gene-targeted mice lacking SGK1. J Mol Med (Berl). 2006 Sep; 84(9):737-46. PMID: 16924469.
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      94. Boini KM, Hennige AM, Huang DY, Friedrich B, Palmada M, Boehmer C, Grahammer F, Artunc F, Ullrich S, Avram D, Osswald H, Wulff P, Kuhl D, Vallon V, Häring HU, Lang F. Serum- and glucocorticoid-inducible kinase 1 mediates salt sensitivity of glucose tolerance. Diabetes. 2006 Jul; 55(7):2059-66. PMID: 16804076.
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      95. Vallon V, Mühlbauer B, Osswald H. Adenosine and kidney function. Physiol Rev. 2006 Jul; 86(3):901-40. PMID: 16816141.
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      96. Satriano J, Vallon V. Primary kidney growth and its consequences at the onset of diabetes mellitus. Amino Acids. 2006 Jul; 31(1):1-9. PMID: 16733619.
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      97. Sandulache D, Grahammer F, Artunc F, Henke G, Hussain A, Nasir O, Mack A, Friedrich B, Vallon V, Wulff P, Kuhl D, Palmada M, Lang F. Renal Ca2+ handling in sgk1 knockout mice. Pflugers Arch. 2006 Jul; 452(4):444-52. PMID: 16685564.
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      98. Vallon V, Wyatt AW, Klingel K, Huang DY, Hussain A, Berchtold S, Friedrich B, Grahammer F, Belaiba RS, Görlach A, Wulff P, Daut J, Dalton ND, Ross J, Flögel U, Schrader J, Osswald H, Kandolf R, Kuhl D, Lang F. SGK1-dependent cardiac CTGF formation and fibrosis following DOCA treatment. J Mol Med (Berl). 2006 May; 84(5):396-404. PMID: 16604333.
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      99. Thomson SC, Deng A, Wead L, Richter K, Blantz RC, Vallon V. An unexpected role for angiotensin II in the link between dietary salt and proximal reabsorption. J Clin Invest. 2006 Apr; 116(4):1110-6. PMID: 16557296.
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      100. Wyatt AW, Hussain A, Amann K, Klingel K, Kandolf R, Artunc F, Grahammer F, Huang DY, Vallon V, Kuhl D, Lang F. DOCA-induced phosphorylation of glycogen synthase kinase 3beta. Cell Physiol Biochem. 2006; 17(3-4):137-44. PMID: 16543730.
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      101. Huang DY, Vallon V, Zimmermann H, Koszalka P, Schrader J, Osswald H. Ecto-5'-nucleotidase (cd73)-dependent and -independent generation of adenosine participates in the mediation of tubuloglomerular feedback in vivo. Am J Physiol Renal Physiol. 2006 Aug; 291(2):F282-8. PMID: 16525161.
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      102. Yao LJ, Leitges M, Vallon V. Mice lacking protein kinase C beta present modest increases in systolic blood pressure and NH4Cl-induced metabolic acidosis. Kidney Blood Press Res. 2006; 29(1):36-42. PMID: 16582576.
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      103. Eraly SA, Vallon V, Vaughn DA, Gangoiti JA, Richter K, Nagle M, Monte JC, Rieg T, Truong DM, Long JM, Barshop BA, Kaler G, Nigam SK. Decreased renal organic anion secretion and plasma accumulation of endogenous organic anions in OAT1 knock-out mice. J Biol Chem. 2006 Feb 24; 281(8):5072-83. PMID: 16354673.
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      104. Vallon V, Grahammer F, Volkl H, Sandu CD, Richter K, Rexhepaj R, Gerlach U, Rong Q, Pfeifer K, Lang F. KCNQ1-dependent transport in renal and gastrointestinal epithelia. Proc Natl Acad Sci U S A. 2005 Dec 6; 102(49):17864-9. PMID: 16314573.
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      105. Huang DY, Boini KM, Friedrich B, Metzger M, Just L, Osswald H, Wulff P, Kuhl D, Vallon V, Lang F. Blunted hypertensive effect of combined fructose and high-salt diet in gene-targeted mice lacking functional serum- and glucocorticoid-inducible kinase SGK1. Am J Physiol Regul Integr Comp Physiol. 2006 Apr; 290(4):R935-44. PMID: 16284089.
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      106. Huang DY, Boini KM, Lang PA, Grahammer F, Duszenko M, Heller-Stilb B, Warskulat U, Häussinger D, Lang F, Vallon V. Impaired ability to increase water excretion in mice lacking the taurine transporter gene TAUT. Pflugers Arch. 2006 Feb; 451(5):668-77. PMID: 16249932.
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      107. Hummler E, Vallon V. Lessons from mouse mutants of epithelial sodium channel and its regulatory proteins. J Am Soc Nephrol. 2005 Nov; 16(11):3160-6. PMID: 16192419.
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      108. Vallon V, Huang DY, Grahammer F, Wyatt AW, Osswald H, Wulff P, Kuhl D, Lang F. SGK1 as a determinant of kidney function and salt intake in response to mineralocorticoid excess. Am J Physiol Regul Integr Comp Physiol. 2005 Aug; 289(2):R395-R401. PMID: 16014448.
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      109. Nie X, Arrighi I, Kaissling B, Pfaff I, Mann J, Barhanin J, Vallon V. Expression and insights on function of potassium channel TWIK-1 in mouse kidney. Pflugers Arch. 2005 Dec; 451(3):479-88. PMID: 16025300.
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      110. Nijenhuis T, Vallon V, van der Kemp AW, Loffing J, Hoenderop JG, Bindels RJ. Enhanced passive Ca2+ reabsorption and reduced Mg2+ channel abundance explains thiazide-induced hypocalciuria and hypomagnesemia. J Clin Invest. 2005 Jun; 115(6):1651-8. PMID: 15902302.
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      111. Vallon V, Blantz R, Thomson S. The salt paradox and its possible implications in managing hypertensive diabetic patients. Curr Hypertens Rep. 2005 Apr; 7(2):141-7. PMID: 15748540.
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      112. Lang F, Vallon V, Grahammer F, Palmada M, Böhmer C. Transport regulation by the serum- and glucocorticoid-inducible kinase SGK1. Biochem Soc Trans. 2005 Feb; 33(Pt 1):213-5. PMID: 15667310.
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      113. Vallon V, Lang F. New insights into the role of serum- and glucocorticoid-inducible kinase SGK1 in the regulation of renal function and blood pressure. Curr Opin Nephrol Hypertens. 2005 Jan; 14(1):59-66. PMID: 15586017.
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      114. Vallon V, Wulff P, Huang DY, Loffing J, Völkl H, Kuhl D, Lang F. Role of Sgk1 in salt and potassium homeostasis. Am J Physiol Regul Integr Comp Physiol. 2005 Jan; 288(1):R4-10. PMID: 15590995.
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      115. Rieg T, Steigele H, Schnermann J, Richter K, Osswald H, Vallon V. Requirement of intact adenosine A1 receptors for the diuretic and natriuretic action of the methylxanthines theophylline and caffeine. J Pharmacol Exp Ther. 2005 Apr; 313(1):403-9. PMID: 15590766.
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      116. Rieg T, Richter K, Osswald H, Vallon V. Kidney function in mice: thiobutabarbital versus alpha-chloralose anesthesia. Naunyn Schmiedebergs Arch Pharmacol. 2004 Oct; 370(4):320-3. PMID: 15549274.
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      117. Loffing J, Vallon V, Loffing-Cueni D, Aregger F, Richter K, Pietri L, Bloch-Faure M, Hoenderop JG, Shull GE, Meneton P, Kaissling B. Altered renal distal tubule structure and renal Na(+) and Ca(2+) handling in a mouse model for Gitelman's syndrome. J Am Soc Nephrol. 2004 Sep; 15(9):2276-88. PMID: 15339977.
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      118. Huang DY, Wulff P, Völkl H, Loffing J, Richter K, Kuhl D, Lang F, Vallon V. Impaired regulation of renal K+ elimination in the sgk1-knockout mouse. J Am Soc Nephrol. 2004 Apr; 15(4):885-91. PMID: 15034090.
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      119. Redling S, Pfaff IL, Leitges M, Vallon V. Immunolocalization of protein kinase C isoenzymes alpha, beta I, beta II, delta, and epsilon in mouse kidney. Am J Physiol Renal Physiol. 2004 Aug; 287(2):F289-98. PMID: 15039141.
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      120. Yao L, Huang DY, Pfaff IL, Nie X, Leitges M, Vallon V. Evidence for a role of protein kinase C-alpha in urine concentration. Am J Physiol Renal Physiol. 2004 Aug; 287(2):F299-304. PMID: 15039142.
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      121. Vallon V, Richter K, Huang DY, Rieg T, Schnermann J. Functional consequences at the single-nephron level of the lack of adenosine A1 receptors and tubuloglomerular feedback in mice. Pflugers Arch. 2004 May; 448(2):214-21. PMID: 14767772.
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      122. Thomson SC, Vallon V, Blantz RC. Kidney function in early diabetes: the tubular hypothesis of glomerular filtration. Am J Physiol Renal Physiol. 2004 Jan; 286(1):F8-15. PMID: 14656757.
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      123. Hoenderop JG, van Leeuwen JP, van der Eerden BC, Kersten FF, van der Kemp AW, Mérillat AM, Waarsing JH, Rossier BC, Vallon V, Hummler E, Bindels RJ. Renal Ca2+ wasting, hyperabsorption, and reduced bone thickness in mice lacking TRPV5. J Clin Invest. 2003 Dec; 112(12):1906-14. PMID: 14679186.
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      124. Lang UE, Lang F, Richter K, Vallon V, Lipp HP, Schnermann J, Wolfer DP. Emotional instability but intact spatial cognition in adenosine receptor 1 knock out mice. Behav Brain Res. 2003 Oct 17; 145(1-2):179-88. PMID: 14529816.
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      125. Vallon V. Tubuloglomerular feedback and the control of glomerular filtration rate. News Physiol Sci. 2003 Aug; 18:169-74. PMID: 12869618.
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      126. Vallon V, Blantz RC, Thomson S. Glomerular hyperfiltration and the salt paradox in early [corrected] type 1 diabetes mellitus: a tubulo-centric view. J Am Soc Nephrol. 2003 Feb; 14(2):530-7. PMID: 12538755.
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      127. Lang F, Henke G, Embark HM, Waldegger S, Palmada M, Böhmer C, Vallon V. Regulation of channels by the serum and glucocorticoid-inducible kinase - implications for transport, excitability and cell proliferation. Cell Physiol Biochem. 2003; 13(1):41-50. PMID: 12649601.
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      128. Vallon V, Schnermann J. Tubuloglomerular feedback. Methods Mol Med. 2003; 86:429-41. PMID: 12886786.
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      129. Vallon V. In vivo studies of the genetically modified mouse kidney. Nephron Physiol. 2003; 94(1):p1-5. PMID: 12806203.
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      130. Lang PA, Warskulat U, Heller-Stilb B, Huang DY, Grenz A, Myssina S, Duszenko M, Lang F, Häussinger D, Vallon V, Wieder T. Blunted apoptosis of erythrocytes from taurine transporter deficient mice. Cell Physiol Biochem. 2003; 13(6):337-46. PMID: 14631140.
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      131. Birk C, Richter K, Huang DY, Piesch C, Luippold G, Vallon V. The salt paradox of the early diabetic kidney is independent of renal innervation. Kidney Blood Press Res. 2003; 26(5-6):344-50. PMID: 14610339.
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      132. Embark HM, Böhmer C, Vallon V, Luft F, Lang F. Regulation of KCNE1-dependent K(+) current by the serum and glucocorticoid-inducible kinase (SGK) isoforms. Pflugers Arch. 2003 Feb; 445(5):601-6. PMID: 12634932.
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      133. Wulff P, Vallon V, Huang DY, Völkl H, Yu F, Richter K, Jansen M, Schlünz M, Klingel K, Loffing J, Kauselmann G, Bösl MR, Lang F, Kuhl D. Impaired renal Na(+) retention in the sgk1-knockout mouse. J Clin Invest. 2002 Nov; 110(9):1263-8. PMID: 12417564.
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      134. Vallon V. Tubuloglomerular feedback in the kidney: insights from gene-targeted mice. Pflugers Arch. 2003 Jan; 445(4):470-6. PMID: 12548391.
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      135. Vallon V, Huang DY, Deng A, Richter K, Blantz RC, Thomson S. Salt-sensitivity of proximal reabsorption alters macula densa salt and explains the paradoxical effect of dietary salt on glomerular filtration rate in diabetes mellitus. J Am Soc Nephrol. 2002 Jul; 13(7):1865-71. PMID: 12089382.
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      136. Blantz RC, Deng A, Lortie M, Munger K, Vallon V, Gabbai FB, Thomson SC. The complex role of nitric oxide in the regulation of glomerular ultrafiltration. Kidney Int. 2002 Mar; 61(3):782-5. PMID: 11849425.
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      137. Pfaff IL, Vallon V. Protein kinase C beta isoenzymes in diabetic kidneys and their relation to nephroprotective actions of the ACE inhibitor lisinopril. Kidney Blood Press Res. 2002; 25(5):329-40. PMID: 12435880.
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      138. Huang DY, Richter K, Breidenbach A, Vallon V. Human C-peptide acutely lowers glomerular hyperfiltration and proteinuria in diabetic rats: a dose-response study. Naunyn Schmiedebergs Arch Pharmacol. 2002 Jan; 365(1):67-73. PMID: 11862335.
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      139. Vallon V, Grahammer F, Richter K, Bleich M, Lang F, Barhanin J, Völkl H, Warth R. Role of KCNE1-dependent K+ fluxes in mouse proximal tubule. J Am Soc Nephrol. 2001 Oct; 12(10):2003-11. PMID: 11562398.
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      140. Vallon V, Traynor T, Barajas L, Huang YG, Briggs JP, Schnermann J. Feedback control of glomerular vascular tone in neuronal nitric oxide synthase knockout mice. J Am Soc Nephrol. 2001 Aug; 12(8):1599-606. PMID: 11461931.
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      141. Thomson SC, Deng A, Bao D, Satriano J, Blantz RC, Vallon V. Ornithine decarboxylase, kidney size, and the tubular hypothesis of glomerular hyperfiltration in experimental diabetes. J Clin Invest. 2001 Jan; 107(2):217-24. PMID: 11160138.
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      142. Huang DY, Pfaff I, Serradeil-Le Gal C, Vallon V. Acute renal response to the non-peptide vasopressin V2-receptor antagonist SR 121463B in anesthetized rats. Naunyn Schmiedebergs Arch Pharmacol. 2000 Sep; 362(3):201-7. PMID: 10997721.
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      143. Thomson S, Bao D, Deng A, Vallon V. Adenosine formed by 5'-nucleotidase mediates tubuloglomerular feedback. J Clin Invest. 2000 Jul; 106(2):289-98. PMID: 10903345.
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      144. Huang DY, Osswald H, Vallon V. Sodium reabsorption in thick ascending limb of Henle's loop: effect of potassium channel blockade in vivo. Br J Pharmacol. 2000 Jul; 130(6):1255-62. PMID: 10903963.
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      145. Vallon V, Verkman AS, Schnermann J. Luminal hypotonicity in proximal tubules of aquaporin-1-knockout mice. Am J Physiol Renal Physiol. 2000 Jun; 278(6):F1030-3. PMID: 10836992.
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      146. Luippold G, Schneider S, Vallon V, Osswald H, Mühlbauer B. Postglomerular vasoconstriction induced by dopamine D(3) receptor activation in anesthetized rats. Am J Physiol Renal Physiol. 2000 Apr; 278(4):F570-5. PMID: 10751217.
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      147. Vallon V, Schwark JR, Richter K, Hropot M. Role of Na(+)/H(+) exchanger NHE3 in nephron function: micropuncture studies with S3226, an inhibitor of NHE3. Am J Physiol Renal Physiol. 2000 Mar; 278(3):F375-9. PMID: 10710541.
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      148. Vallon V, Richter K, Blantz RC, Thomson S, Osswald H. Glomerular hyperfiltration in experimental diabetes mellitus: potential role of tubular reabsorption. J Am Soc Nephrol. 1999 Dec; 10(12):2569-76. PMID: 10589696.
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      149. Pfaff IL, Wagner HJ, Vallon V. Immunolocalization of protein kinase C isoenzymes alpha, beta1 and betaII in rat kidney. J Am Soc Nephrol. 1999 Sep; 10(9):1861-73. PMID: 10477137.
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      150. Huang DY, Osswald H, Vallon V. Eukaliuric diuresis and natriuresis in response to the KATP channel blocker U37883A: micropuncture studies on the tubular site of action. Br J Pharmacol. 1999 Aug; 127(8):1811-8. PMID: 10482911.
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      151. Luippold G, Küster E, Vallon V, Osswald H, Mühlbauer B. Dopamine D3 receptors in the rat kidney: glomerular and tubular actions. Nephrol Dial Transplant. 1999; 14 Suppl 4:24-5. PMID: 10463201.
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      152. Huang DY, Osswald H, Vallon V. Intratubular application of sodium azide inhibits loop of Henle reabsorption and tubuloglomerular feedback response in anesthetized rats. Naunyn Schmiedebergs Arch Pharmacol. 1998 Sep; 358(3):367-73. PMID: 9774225.
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      153. Vallon V, Albinus M, Blach D. Effect of KATP channel blocker U37883A on renal function in experimental diabetes mellitus in rats. J Pharmacol Exp Ther. 1998 Sep; 286(3):1215-21. PMID: 9732381.
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      154. Thomson SC, Vallon V, Blantz RC. Resetting protects efficiency of tubuloglomerular feedback. Kidney Int Suppl. 1998 Sep; 67:S65-70. PMID: 9736256.
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      155. Vallon V, Osswald H, Blantz RC, Thomson S. Luminal signal in tubuloglomerular feedback: what about potassium? Kidney Int Suppl. 1998 Sep; 67:S177-9. PMID: 9736282.
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      156. Vallon V, Richter K, Osswald H, Schömig E, Mühlbauer B. Eukaliuric natriuresis and diuresis in response to disprocynium24: studies on the tubular site of action. Naunyn Schmiedebergs Arch Pharmacol. 1998 Aug; 358(2):238-44. PMID: 9750010.
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      157. Vallon V, Kirschenmann D, Brenner I, Albinus M, Osswald H. Potassium diet as a determinant for the renal response to systemic potassium channel modulation in anesthetized rats. Naunyn Schmiedebergs Arch Pharmacol. 1998 Aug; 358(2):245-52. PMID: 9750011.
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      158. Vallon V, Heyne N, Richter K, Khosla MC, Fechter K. [7-D-ALA]-angiotensin 1-7 blocks renal actions of angiotensin 1-7 in the anesthetized rat. J Cardiovasc Pharmacol. 1998 Jul; 32(1):164-7. PMID: 9676737.
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      159. Vallon V, Osswald H, Blantz RC, Thomson S. Potential role of luminal potassium in tubuloglomerular feedback. J Am Soc Nephrol. 1997 Dec; 8(12):1831-7. PMID: 9402084.
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      160. Mühlbauer B, Luippold G, Vallon V, Spitzenberger F, Russ H, Osswald H, Schömig E. Disprocynium24 induces a dopamine-independent, eukaliuric diuresis and natriuresis in the anaesthetized rat. Naunyn Schmiedebergs Arch Pharmacol. 1997 Dec; 356(6):846-9. PMID: 9453472.
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      161. Thomson SC, Vallon V, Blantz RC. Reduced proximal reabsorption resets tubuloglomerular feedback in euvolemic rats. Am J Physiol. 1997 Oct; 273(4 Pt 2):R1414-20. PMID: 9362307.
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      162. Vallon V, Kirschenmann D, Wead LM, Lortie MJ, Satriano J, Blantz RC, Thomson SC. Effect of chronic salt loading on kidney function in early and established diabetes mellitus in rats. J Lab Clin Med. 1997 Jul; 130(1):76-82. PMID: 9242369.
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      163. Vallon V, Richter K, Heyne N, Osswald H. Effect of intratubular application of angiotensin 1-7 on nephron function. Kidney Blood Press Res. 1997; 20(4):233-9. PMID: 9398028.
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      164. Osswald H, Mühlbauer B, Vallon V. Adenosine and tubuloglomerular feedback. Blood Purif. 1997; 15(4-6):243-52. PMID: 9435952.
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      165. Thomson S, Vallon V, Blantz RC. Asymmetry of tubuloglomerular feedback effector mechanism with respect to ambient tubular flow. Am J Physiol. 1996 Dec; 271(6 Pt 2):F1123-30. PMID: 8997385.
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      166. Osswald H, Vallon V, Mühlbauer B. Role of adenosine in tubuloglomerular feedback and acute renal failure. J Auton Pharmacol. 1996 Dec; 16(6):377-80. PMID: 9131420.
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      167. Blantz RC, Lortie M, Vallon V, Gabbai FB, Parmer RJ, Thomson S. Activities of nitric oxide in normal physiology and uremia. Semin Nephrol. 1996 May; 16(3):144-50. PMID: 8734457.
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      168. Thomson SC, Blantz RC, Vallon V. Increased tubular flow induces resetting of tubuloglomerular feedback in euvolemic rats. Am J Physiol. 1996 Mar; 270(3 Pt 2):F461-8. PMID: 8780249.
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      169. Lortie MJ, Novotny WF, Peterson OW, Vallon V, Malvey K, Mendonca M, Satriano J, Insel P, Thomson SC, Blantz RC. Agmatine, a bioactive metabolite of arginine. Production, degradation, and functional effects in the kidney of the rat. J Clin Invest. 1996 Jan 15; 97(2):413-20. PMID: 8567962.
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      170. Vallon V, Thomson S. Inhibition of local nitric oxide synthase increases homeostatic efficiency of tubuloglomerular feedback. Am J Physiol. 1995 Dec; 269(6 Pt 2):F892-9. PMID: 8594885.
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      171. Vallon V, Blantz RC, Thomson S. Homeostatic efficiency of tubuloglomerular feedback is reduced in established diabetes mellitus in rats. Am J Physiol. 1995 Dec; 269(6 Pt 2):F876-83. PMID: 8594883.
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      172. Vallon V, Peterson OW, Gabbai FB, Blantz RC, Thomson SC. Interactive control of renal function by alpha 2-adrenergic system and nitric oxide: role of angiotensin II. J Cardiovasc Pharmacol. 1995 Dec; 26(6):916-22. PMID: 8606528.
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      173. Thomson SC, Vallon V. Alpha 2-adrenoceptors determine the response to nitric oxide inhibition in the rat glomerulus and proximal tubule. J Am Soc Nephrol. 1995 Nov; 6(5):1482-90. PMID: 8589327.
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      174. Vallon V, Wead LM, Blantz RC. Renal hemodynamics and plasma and kidney angiotensin II in established diabetes mellitus in rats: effect of sodium and salt restriction. J Am Soc Nephrol. 1995 Apr; 5(10):1761-7. PMID: 7787143.
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      175. Vallon V, Osswald H. Dipyridamole prevents diabetes-induced alterations of kidney function in rats. Naunyn Schmiedebergs Arch Pharmacol. 1994 Feb; 349(2):217-22. PMID: 8170506.
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