William Wachsman

Title(s)Senate Emeritus, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    NIH U01CA083035Sep 22, 1999 - Aug 31, 2006
    Role: Principal Investigator
    NIH R01CA059713Feb 18, 1994 - Jan 31, 1998
    Role: Principal Investigator
    NIH K08CA001113Jul 1, 1986 - Nov 30, 1989
    Role: Principal Investigator
    NIH R01CA043370Jul 1, 1986 - Jun 30, 1989
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Phase I Trial of the Multi-kinase Inhibitor Cabozantinib, a CYP3A4 Substrate, plus CYP3A4-Interacting Antiretroviral Therapy in People Living with HIV and Cancer (AMC-087). Clin Cancer Res. 2023 12 15; 29(24):5038-5046. Haigentz M, Lee JY, Chiao EY, Aboulafia DM, Ratner L, Ambinder RF, Baiocchi RA, Mitsuyasu RT, Wachsman W, Sparano JA, Rudek MA. PMID: 37523145; PMCID: PMC10829065.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsCTClinical Trials
    2. AMC-070: Lenalidomide Is Safe and Effective in HIV-Associated Kaposi Sarcoma. Clin Cancer Res. 2022 06 13; 28(12):2646-2656. Reid EG, Shimabukuro K, Moore P, Ambinder RF, Bui JD, Han S, Martínez-Maza O, Dittmer DP, Aboulafia D, Chiao EY, Maurer T, Baiocchi R, Mitsuyasu R, Wachsman W, AIDS Malignancy Consortium (AMC). PMID: 35247913; PMCID: PMC9197984.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    3. Immune Recovery Following Autologous Hematopoietic Stem Cell Transplantation in HIV-Related Lymphoma Patients on the BMT CTN 0803/AMC 071 Trial. Front Immunol. 2021; 12:700045. Shindiapina P, Pietrzak M, Seweryn M, McLaughlin E, Zhang X, Makowski M, Ahmed EH, Schlotter S, Pearson R, Kitzler R, Mozhenkova A, Le-Rademacher J, Little RF, Akpek G, Ayala E, Devine SM, Kaplan LD, Noy A, Popat UR, Hsu JW, Morris LE, Mendizabal AM, Krishnan A, Wachsman W, Williams N, Sharma N, Hofmeister CC, Forman SJ, Navarro WH, Alvarnas JC, Ambinder RF, Lozanski G, Baiocchi RA. PMID: 34539628; PMCID: PMC8446430.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    4. Response-adapted therapy with infusional EPOCH chemotherapy plus rituximab in HIV-associated, B-cell non-Hodgkin's lymphoma. Haematologica. 2021 03 01; 106(3):730-735. Sparano JA, Lee JY, Kaplan LD, Ramos JC, Ambinder RF, Wachsman W, Aboulafia D, Noy A, Henry DH, Ratner L, Cesarman E, Chadburn A, Mitsuyasu R. PMID: 32107337; PMCID: PMC7927888.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    5. Pilot Trial AMC-063: Safety and Efficacy of Bortezomib in AIDS-associated Kaposi Sarcoma. Clin Cancer Res. 2020 02 01; 26(3):558-565. Reid EG, Suazo A, Lensing SY, Dittmer DP, Ambinder RF, Maldarelli F, Gorelick RJ, Aboulafia D, Mitsuyasu R, Dickson MA, Wachsman W, AIDS Malignancy Consortium (AMC). PMID: 31624104; PMCID: PMC7034393.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCellsCTClinical Trials
    6. Safety and efficacy of an oncolytic viral strategy using bortezomib with ICE/R in relapsed/refractory HIV-positive lymphomas. Blood Adv. 2018 12 26; 2(24):3618-3626. Reid EG, Looney D, Maldarelli F, Noy A, Henry D, Aboulafia D, Ramos JC, Sparano J, Ambinder RF, Lee J, Cesarman E, Yahyaei S, Mitsuyasu R, Wachsman W, AIDS Malignancy Consortium. PMID: 30573564; PMCID: PMC6306883.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCellsCTClinical Trials
    7. Cetuximab Plus Chemoradiotherapy for HIV-Associated Anal Carcinoma: A Phase II AIDS Malignancy Consortium Trial. J Clin Oncol. 2017 Mar; 35(7):727-733. Sparano JA, Lee JY, Palefsky J, Henry DH, Wachsman W, Rajdev L, Aboulafia D, Ratner L, Fitzgerald TJ, Kachnic L, Mitsuyasu R. PMID: 27937092; PMCID: PMC5455422.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCTClinical Trials
    8. Plasmablastic lymphoma is treatable in the HAART era. A 10 year retrospective by the AIDS Malignancy Consortium. Leuk Lymphoma. 2016 07; 57(7):1731-4. Noy A, Lensing SY, Moore PC, Gupta N, Aboulafia D, Ambinder R, Baiocchi R, Dezube BJ, Henry D, Kaplan L, Levine AM, Mitsuyasu R, Ratner L, Reid E, Remick S, Sparano J, Tzachanis D, Wachsman W, Chadburn A. PMID: 26674561; PMCID: PMC4899288.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    9. Noninvasive genomic detection of melanoma. Br J Dermatol. 2011 Apr; 164(4):797-806. Wachsman W, Morhenn V, Palmer T, Walls L, Hata T, Zalla J, Scheinberg R, Sofen H, Mraz S, Gross K, Rabinovitz H, Polsky D, Chang S. PMID: 21294715; PMCID: PMC3118279.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    10. Time for oncologists to opt in for routine opt-out HIV testing? JAMA. 2010 Jul 21; 304(3):334-9. Chiao EY, Dezube BJ, Krown SE, Wachsman W, Brock MV, Giordano TP, Mitsuyasu R, Pantanowitz L. PMID: 20639567; PMCID: PMC3160789.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansPHPublic Health
    11. Rituximab plus concurrent infusional EPOCH chemotherapy is highly effective in HIV-associated B-cell non-Hodgkin lymphoma. Blood. 2010 Apr 15; 115(15):3008-16. Sparano JA, Lee JY, Kaplan LD, Levine AM, Ramos JC, Ambinder RF, Wachsman W, Aboulafia D, Noy A, Henry DH, Von Roenn J, Dezube BJ, Remick SC, Shah MH, Leichman L, Ratner L, Cesarman E, Chadburn A, Mitsuyasu R, AIDS Malignancy Consortium. PMID: 20023215; PMCID: PMC2858478.
      View in: PubMed   Mentions: 88     Fields:    Translation:HumansCellsCTClinical Trials
    12. Molecular and clinical assessment in the treatment of AIDS Kaposi sarcoma with valproic Acid. Clin Infect Dis. 2009 Dec 15; 49(12):1946-9. Lechowicz M, Dittmer DP, Lee JY, Krown SE, Wachsman W, Aboulafia D, Dezube BJ, Ratner L, Said J, Ambinder RF. PMID: 19911999; PMCID: PMC2952388.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    13. Dose-reduced busulfan, cyclophosphamide, and autologous stem cell transplantation for human immunodeficiency virus-associated lymphoma: AIDS Malignancy Consortium study 020. Biol Blood Marrow Transplant. 2008 Jan; 14(1):59-66. Spitzer TR, Ambinder RF, Lee JY, Kaplan LD, Wachsman W, Straus DJ, Aboulafia DM, Scadden DT. PMID: 18158962; PMCID: PMC4524737.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCTClinical Trials
    14. Bortezomib is effective in primary plasma cell leukemia. Leuk Lymphoma. 2006 Aug; 47(8):1670-3. Finnegan DP, Kettle P, Drake M, Matthews C, Alexander HD, Popat R, Cavanagh JD, Wachsman W, Morris TC. PMID: 16966282.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    15. Identifying progression-associated genes in adult T-cell leukemia/lymphoma by using oligonucleotide microarrays. Int J Cancer. 2004 May 10; 109(6):875-81. Tsukasaki K, Tanosaki S, DeVos S, Hofmann WK, Wachsman W, Gombart AF, Krebs J, Jauch A, Bartram CR, Nagai K, Tomonaga M, Said JW, Koeffler HP. PMID: 15027121.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    16. In silico dissection of cell-type-associated patterns of gene expression in prostate cancer. Proc Natl Acad Sci U S A. 2004 Jan 13; 101(2):615-20. Stuart RO, Wachsman W, Berry CC, Wang-Rodriguez J, Wasserman L, Klacansky I, Masys D, Arden K, Goodison S, McClelland M, Wang Y, Sawyers A, Kalcheva I, Tarin D, Mercola D. PMID: 14722351; PMCID: PMC327196.
      View in: PubMed   Mentions: 95     Fields:    Translation:HumansCells
    17. Cell cycle alterations in the blastoid variant of mantle cell lymphoma (MCL-BV) as detected by gene expression profiling of mantle cell lymphoma (MCL) and MCL-BV. Diagn Mol Pathol. 2003 Mar; 12(1):35-43. de Vos S, Krug U, Hofmann WK, Pinkus GS, Swerdlow SH, Wachsman W, Grogan TM, Said JW, Koeffler HP. PMID: 12605034.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    18. Gene expression profile of serial samples of transformed B-cell lymphomas. Lab Invest. 2003 Feb; 83(2):271-85. de Vos S, Hofmann WK, Grogan TM, Krug U, Schrage M, Miller TP, Braun JG, Wachsman W, Koeffler HP, Said JW. PMID: 12594241.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    19. Correlation of transcriptional repression by p21(SNFT) with changes in DNA.NF-AT complex interactions. J Biol Chem. 2002 Sep 20; 277(38):34967-77. Bower KE, Zeller RW, Wachsman W, Martinez T, McGuire KL. PMID: 12087103.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    20. Multiple fibroblast growth factors support growth of the ureteric bud but have different effects on branching morphogenesis. Mech Dev. 2001 Dec; 109(2):123-35. Qiao J, Bush KT, Steer DL, Stuart RO, Sakurai H, Wachsman W, Nigam SK. PMID: 11731227.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    21. Altered apoptosis pathways in mantle cell lymphoma detected by oligonucleotide microarray. Blood. 2001 Aug 01; 98(3):787-94. Hofmann WK, de Vos S, Tsukasaki K, Wachsman W, Pinkus GS, Said JW, Koeffler HP. PMID: 11468180.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    22. Repression of IL-2 promoter activity by the novel basic leucine zipper p21SNFT protein. J Immunol. 2000 Jul 15; 165(2):860-8. Iacobelli M, Wachsman W, McGuire KL. PMID: 10878360.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    23. Stimulation of HIV replication in mononuclear phagocytes by leukemia inhibitory factor. J Acquir Immune Defic Syndr (1988). 1994 Jul; 7(7):647-54. Broor S, Kusari AB, Zhang B, Seth P, Richman DD, Carson DA, Wachsman W, Lotz M. PMID: 8207643.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    24. Interaction of host cell proteins with the human T-cell leukemia virus type I transcriptional control region. II. A comprehensive map of protein-binding sites facilitates construction of a simple chimeric promoter responsive to the viral tax2 gene product. J Biol Chem. 1990 May 15; 265(14):8237-42. Nyborg JK, Matthews MA, Yucel J, Walls L, Golde WT, Dynan WS, Wachsman W. PMID: 2186038.
      View in: PubMed   Mentions: 25     Fields:    Translation:Cells
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