William Wachsman

Title(s)	Senate Emeritus, Medicine
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
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Overview

webpage

Divisions of Hematology-Oncology and Bone Marrow Transplantation

Research

research activities and funding

AIDS-RELATED MALIGNANCIES CONSORTIUM--UC SAN DIEGO
NIH U01CA083035Sep 22, 1999 - Aug 31, 2006
Role: Principal Investigator

TAX RESPONSE COMPLEX-1 AND HTLV PATHOGENESIS
NIH R01CA059713Feb 18, 1994 - Jan 31, 1998
Role: Principal Investigator

MOLECULAR STUDIES ON HTLV X GENE PRODUCT/LTR INTERACTION
NIH K08CA001113Jul 1, 1986 - Nov 30, 1989
Role: Principal Investigator

HUMAN RETROVIRUSES AND HAIRY-CELL LEUKEMIA
NIH R01CA043370Jul 1, 1986 - Jun 30, 1989
Role: Principal Investigator

ORNG Applications

Clinical Trials

Bibliographic

selected publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

Altmetrics Details

PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Phase I Trial of the Multi-kinase Inhibitor Cabozantinib, a CYP3A4 Substrate, plus CYP3A4-Interacting Antiretroviral Therapy in People Living with HIV and Cancer (AMC-087). Clin Cancer Res. 2023 12 15; 29(24):5038-5046. Haigentz M, Lee JY, Chiao EY, Aboulafia DM, Ratner L, Ambinder RF, Baiocchi RA, Mitsuyasu RT, Wachsman W, Sparano JA, Rudek MA. PMID: 37523145; PMCID: PMC10829065.

View in: PubMed Mentions: Fields:
Neo Neoplasms
Translation:Humans Cells CTClinical Trials
AMC-070: Lenalidomide Is Safe and Effective in HIV-Associated Kaposi Sarcoma. Clin Cancer Res. 2022 06 13; 28(12):2646-2656. Reid EG, Shimabukuro K, Moore P, Ambinder RF, Bui JD, Han S, Martínez-Maza O, Dittmer DP, Aboulafia D, Chiao EY, Maurer T, Baiocchi R, Mitsuyasu R, Wachsman W, AIDS Malignancy Consortium (AMC). PMID: 35247913; PMCID: PMC9197984.

View in: PubMed Mentions: 9 Fields:
Neo Neoplasms
Translation:Humans Cells
Immune Recovery Following Autologous Hematopoietic Stem Cell Transplantation in HIV-Related Lymphoma Patients on the BMT CTN 0803/AMC 071 Trial. Front Immunol. 2021; 12:700045. Shindiapina P, Pietrzak M, Seweryn M, McLaughlin E, Zhang X, Makowski M, Ahmed EH, Schlotter S, Pearson R, Kitzler R, Mozhenkova A, Le-Rademacher J, Little RF, Akpek G, Ayala E, Devine SM, Kaplan LD, Noy A, Popat UR, Hsu JW, Morris LE, Mendizabal AM, Krishnan A, Wachsman W, Williams N, Sharma N, Hofmeister CC, Forman SJ, Navarro WH, Alvarnas JC, Ambinder RF, Lozanski G, Baiocchi RA. PMID: 34539628; PMCID: PMC8446430.

View in: PubMed Mentions: 2 Fields:
All Allergy and Immunology
Translation:Humans
Response-adapted therapy with infusional EPOCH chemotherapy plus rituximab in HIV-associated, B-cell non-Hodgkin's lymphoma. Haematologica. 2021 03 01; 106(3):730-735. Sparano JA, Lee JY, Kaplan LD, Ramos JC, Ambinder RF, Wachsman W, Aboulafia D, Noy A, Henry DH, Ratner L, Cesarman E, Chadburn A, Mitsuyasu R. PMID: 32107337; PMCID: PMC7927888.

View in: PubMed Mentions: 6 Fields:
Hem Hematology
Translation:Humans Cells
Pilot Trial AMC-063: Safety and Efficacy of Bortezomib in AIDS-associated Kaposi Sarcoma. Clin Cancer Res. 2020 02 01; 26(3):558-565. Reid EG, Suazo A, Lensing SY, Dittmer DP, Ambinder RF, Maldarelli F, Gorelick RJ, Aboulafia D, Mitsuyasu R, Dickson MA, Wachsman W, AIDS Malignancy Consortium (AMC). PMID: 31624104; PMCID: PMC7034393.

View in: PubMed Mentions: 7 Fields:
Neo Neoplasms
Translation:Humans Cells CTClinical Trials
Safety and efficacy of an oncolytic viral strategy using bortezomib with ICE/R in relapsed/refractory HIV-positive lymphomas. Blood Adv. 2018 12 26; 2(24):3618-3626. Reid EG, Looney D, Maldarelli F, Noy A, Henry D, Aboulafia D, Ramos JC, Sparano J, Ambinder RF, Lee J, Cesarman E, Yahyaei S, Mitsuyasu R, Wachsman W, AIDS Malignancy Consortium. PMID: 30573564; PMCID: PMC6306883.

View in: PubMed Mentions: 8 Fields:
Hem Hematology
Translation:Humans Cells CTClinical Trials
Cetuximab Plus Chemoradiotherapy for HIV-Associated Anal Carcinoma: A Phase II AIDS Malignancy Consortium Trial. J Clin Oncol. 2017 Mar; 35(7):727-733. Sparano JA, Lee JY, Palefsky J, Henry DH, Wachsman W, Rajdev L, Aboulafia D, Ratner L, Fitzgerald TJ, Kachnic L, Mitsuyasu R. PMID: 27937092; PMCID: PMC5455422.

View in: PubMed Mentions: 23 Fields:
Neo Neoplasms
Translation:Humans CTClinical Trials
Plasmablastic lymphoma is treatable in the HAART era. A 10 year retrospective by the AIDS Malignancy Consortium. Leuk Lymphoma. 2016 07; 57(7):1731-4. Noy A, Lensing SY, Moore PC, Gupta N, Aboulafia D, Ambinder R, Baiocchi R, Dezube BJ, Henry D, Kaplan L, Levine AM, Mitsuyasu R, Ratner L, Reid E, Remick S, Sparano J, Tzachanis D, Wachsman W, Chadburn A. PMID: 26674561; PMCID: PMC4899288.

View in: PubMed Mentions: 14 Fields:
Hem Hematology Neo Neoplasms
Translation:Humans
Noninvasive genomic detection of melanoma. Br J Dermatol. 2011 Apr; 164(4):797-806. Wachsman W, Morhenn V, Palmer T, Walls L, Hata T, Zalla J, Scheinberg R, Sofen H, Mraz S, Gross K, Rabinovitz H, Polsky D, Chang S. PMID: 21294715; PMCID: PMC3118279.

View in: PubMed Mentions: 31 Fields:
Der Dermatology
Translation:Humans
Time for oncologists to opt in for routine opt-out HIV testing? JAMA. 2010 Jul 21; 304(3):334-9. Chiao EY, Dezube BJ, Krown SE, Wachsman W, Brock MV, Giordano TP, Mitsuyasu R, Pantanowitz L. PMID: 20639567; PMCID: PMC3160789.

View in: PubMed Mentions: 20 Fields:
Med Medicine (General)
Rituximab plus concurrent infusional EPOCH chemotherapy is highly effective in HIV-associated B-cell non-Hodgkin lymphoma. Blood. 2010 Apr 15; 115(15):3008-16. Sparano JA, Lee JY, Kaplan LD, Levine AM, Ramos JC, Ambinder RF, Wachsman W, Aboulafia D, Noy A, Henry DH, Von Roenn J, Dezube BJ, Remick SC, Shah MH, Leichman L, Ratner L, Cesarman E, Chadburn A, Mitsuyasu R, AIDS Malignancy Consortium. PMID: 20023215; PMCID: PMC2858478.

View in: PubMed Mentions: 87 Fields:
Hem Hematology
Translation:Humans Cells CTClinical Trials
Molecular and clinical assessment in the treatment of AIDS Kaposi sarcoma with valproic Acid. Clin Infect Dis. 2009 Dec 15; 49(12):1946-9. Lechowicz M, Dittmer DP, Lee JY, Krown SE, Wachsman W, Aboulafia D, Dezube BJ, Ratner L, Said J, Ambinder RF. PMID: 19911999; PMCID: PMC2952388.

View in: PubMed Mentions: 13 Fields:
Com Communicable Diseases
Dose-reduced busulfan, cyclophosphamide, and autologous stem cell transplantation for human immunodeficiency virus-associated lymphoma: AIDS Malignancy Consortium study 020. Biol Blood Marrow Transplant. 2008 Jan; 14(1):59-66. Spitzer TR, Ambinder RF, Lee JY, Kaplan LD, Wachsman W, Straus DJ, Aboulafia DM, Scadden DT. PMID: 18158962; PMCID: PMC4524737.

View in: PubMed Mentions: 26 Fields:
Hem Hematology Tra Transplantation
Translation:Humans CTClinical Trials
Bortezomib is effective in primary plasma cell leukemia. Leuk Lymphoma. 2006 Aug; 47(8):1670-3. Finnegan DP, Kettle P, Drake M, Matthews C, Alexander HD, Popat R, Cavanagh JD, Wachsman W, Morris TC. PMID: 16966282.

View in: PubMed Mentions: 6 Fields:
Hem Hematology Neo Neoplasms
Translation:Humans
Identifying progression-associated genes in adult T-cell leukemia/lymphoma by using oligonucleotide microarrays. Int J Cancer. 2004 May 10; 109(6):875-81. Tsukasaki K, Tanosaki S, DeVos S, Hofmann WK, Wachsman W, Gombart AF, Krebs J, Jauch A, Bartram CR, Nagai K, Tomonaga M, Said JW, Koeffler HP. PMID: 15027121.

View in: PubMed Mentions: 16 Fields:
Neo Neoplasms
Translation:Humans Cells
In silico dissection of cell-type-associated patterns of gene expression in prostate cancer. Proc Natl Acad Sci U S A. 2004 Jan 13; 101(2):615-20. Stuart RO, Wachsman W, Berry CC, Wang-Rodriguez J, Wasserman L, Klacansky I, Masys D, Arden K, Goodison S, McClelland M, Wang Y, Sawyers A, Kalcheva I, Tarin D, Mercola D. PMID: 14722351; PMCID: PMC327196.

View in: PubMed Mentions: 89 Fields:
Sci Science
Translation:Humans Cells
Cell cycle alterations in the blastoid variant of mantle cell lymphoma (MCL-BV) as detected by gene expression profiling of mantle cell lymphoma (MCL) and MCL-BV. Diagn Mol Pathol. 2003 Mar; 12(1):35-43. de Vos S, Krug U, Hofmann WK, Pinkus GS, Swerdlow SH, Wachsman W, Grogan TM, Said JW, Koeffler HP. PMID: 12605034.

View in: PubMed Mentions: 15 Fields:
Mol Molecular Biology Pat Pathology
Translation:Humans Cells
Gene expression profile of serial samples of transformed B-cell lymphomas. Lab Invest. 2003 Feb; 83(2):271-85. de Vos S, Hofmann WK, Grogan TM, Krug U, Schrage M, Miller TP, Braun JG, Wachsman W, Koeffler HP, Said JW. PMID: 12594241.

View in: PubMed Mentions: 34 Fields:
Cli Clinical Laboratory Techniques Pat Pathology
Translation:Humans
Characterization of gene expression of CD34+ cells from normal and myelodysplastic bone marrow. Blood. 2002 Nov 15; 100(10):3553-60. Hofmann WK, de Vos S, Komor M, Hoelzer D, Wachsman W, Koeffler HP. PMID: 12411319.

View in: PubMed Mentions: 64 Fields:
Hem Hematology
Translation:Humans Cells
Correlation of transcriptional repression by p21(SNFT) with changes in DNA.NF-AT complex interactions. J Biol Chem. 2002 Sep 20; 277(38):34967-77. Bower KE, Zeller RW, Wachsman W, Martinez T, McGuire KL. PMID: 12087103.

View in: PubMed Mentions: 9 Fields:
Bio Biochemistry
Translation:Humans Cells
Multiple fibroblast growth factors support growth of the ureteric bud but have different effects on branching morphogenesis. Mech Dev. 2001 Dec; 109(2):123-35. Qiao J, Bush KT, Steer DL, Stuart RO, Sakurai H, Wachsman W, Nigam SK. PMID: 11731227.

View in: PubMed Mentions: 41 Fields:
Cel Cell Biology Emb Embryology
Translation:Animals Cells
Altered apoptosis pathways in mantle cell lymphoma detected by oligonucleotide microarray. Blood. 2001 Aug 01; 98(3):787-94. Hofmann WK, de Vos S, Tsukasaki K, Wachsman W, Pinkus GS, Said JW, Koeffler HP. PMID: 11468180.

View in: PubMed Mentions: 34 Fields:
Hem Hematology
Translation:Humans Cells
Repression of IL-2 promoter activity by the novel basic leucine zipper p21SNFT protein. J Immunol. 2000 Jul 15; 165(2):860-8. Iacobelli M, Wachsman W, McGuire KL. PMID: 10878360.

View in: PubMed Mentions: 31 Fields:
All Allergy and Immunology
Translation:Humans Cells
Stimulation of HIV replication in mononuclear phagocytes by leukemia inhibitory factor. J Acquir Immune Defic Syndr (1988). 1994 Jul; 7(7):647-54. Broor S, Kusari AB, Zhang B, Seth P, Richman DD, Carson DA, Wachsman W, Lotz M. PMID: 8207643.

View in: PubMed Mentions: 1 Fields:
Acq Acquired Immunodeficiency Synd Sex Sexually Transmitted Diseases
Translation:Humans Cells
Interaction of host cell proteins with the human T-cell leukemia virus type I transcriptional control region. II. A comprehensive map of protein-binding sites facilitates construction of a simple chimeric promoter responsive to the viral tax2 gene product. J Biol Chem. 1990 May 15; 265(14):8237-42. Nyborg JK, Matthews MA, Yucel J, Walls L, Golde WT, Dynan WS, Wachsman W. PMID: 2186038.

View in: PubMed Mentions: 25 Fields:
Bio Biochemistry
Translation:Cells