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Cachexia: A systemic consequence of progressive, unresolved disease. Cell. 2023 Apr 27; 186(9):1824-1845.
Ferrer M, Anthony TG, Ayres JS, Biffi G, Brown JC, Caan BJ, Cespedes Feliciano EM, Coll AP, Dunne RF, Goncalves MD, Grethlein J, Heymsfield SB, Hui S, Jamal-Hanjani M, Lam JM, Lewis DY, McCandlish D, Mustian KM, O'Rahilly S, Perrimon N, White EP, Janowitz T. PMID: 37116469.
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PubMed Mentions: Fields:
Translation:
Humans
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Age-dependent roles of cardiac remodeling in sepsis defense and pathogenesis. bioRxiv. 2023 Mar 15.
Sanchez KK, McCarville JL, Stengel SJ, Snyder JM, Williams AE, Ayres JS. PMID: 36993409; PMCID: PMC10055033.
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PubMed Mentions:
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Cooperation between physiological defenses and immune resistance produces asymptomatic carriage of a lethal bacterial pathogen. bioRxiv. 2023 Feb 26.
Chen GY, Thorup NR, Miller AJ, Li YC, Ayres JS. PMID: 36711884; PMCID: PMC9882269.
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PubMed Mentions:
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Chronic Leptin Deficiency Improves Tolerance of Physiological Damage and Host-Pathogen Cooperation during Yersinia pseudotuberculosis Infection. Infect Immun. 2022 09 15; 90(9):e0024222.
Sanchez KK, Troha K, Mu A, Redford SE, McCarville JL, Insenga A, Stengel S, Lee YM, Ayres JS. PMID: 35924898; PMCID: PMC9476980.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Virulence triggered allergies: Pseudomonas gets the Las laugh. Immunity. 2022 05 10; 55(5):824-826.
McCarville JL, Ayres JS. PMID: 35545032.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Adipose triglyceride lipase mediates lipolysis and lipid mobilization in response to iron-mediated negative energy balance. iScience. 2022 Mar 18; 25(3):103941.
Romero AR, Mu A, Ayres JS. PMID: 35265813; PMCID: PMC8899412.
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PubMed Mentions:
2
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Cooperative defenses during enteropathogenic infection. Curr Opin Microbiol. 2022 02; 65:123-130.
Troha K, Ayres JS. PMID: 34847524; PMCID: PMC8818259.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Microbiota control of maternal behavior regulates early postnatal growth of offspring. Sci Adv. 2021 01; 7(5).
Lee YM, Mu A, Wallace M, Gengatharan JM, Furst AJ, Bode L, Metallo CM, Ayres JS. PMID: 33514556; PMCID: PMC7846171.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Beyond tug-of-war: Iron metabolism in cooperative host-microbe interactions. PLoS Pathog. 2020 08; 16(8):e1008698.
Chen GY, Ayres JS. PMID: 32785251; PMCID: PMC7423093.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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A metabolic handbook for the COVID-19 pandemic. Nat Metab. 2020 07; 2(7):572-585.
Ayres JS. PMID: 32694793; PMCID: PMC7325641.
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PubMed Mentions:
119 Fields:
Translation:
HumansPHPublic Health
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Surviving COVID-19: A disease tolerance perspective. Sci Adv. 2020 05; 6(18):eabc1518.
Ayres JS. PMID: 32494691; PMCID: PMC7190329.
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PubMed Mentions:
17 Fields:
Translation:
HumansCellsPHPublic Health
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Microbiota Metabolites in Health and Disease. Annu Rev Immunol. 2020 04 26; 38:147-170.
McCarville JL, Chen GY, Cuevas VD, Troha K, Ayres JS. PMID: 32340573.
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PubMed Mentions:
48 Fields:
Translation:
HumansAnimals
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The Biology of Physiological Health. Cell. 2020 04 16; 181(2):250-269.
Ayres JS. PMID: 32302569; PMCID: PMC7409982.
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PubMed Mentions:
25 Fields:
Translation:
Humans
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Immunometabolism of infections. Nat Rev Immunol. 2020 02; 20(2):79-80.
Ayres JS. PMID: 31892735.
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PubMed Mentions:
28 Fields:
Translation:
HumansAnimalsCells
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Metabolic Adaptations to Infections at the Organismal Level. Trends Immunol. 2020 02; 41(2):113-125.
Troha K, Ayres JS. PMID: 31959515; PMCID: PMC7409656.
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PubMed Mentions:
25 Fields:
Translation:
Humans
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Host-Pathogen Relationship Advice: Fat Protects against a Broken Heart. Cell Metab. 2019 09 03; 30(3):409-411.
McCarville JL, Ayres JS. PMID: 31484052.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Enzyme promiscuity drives branched-chain fatty acid synthesis in adipose tissues. Nat Chem Biol. 2018 11; 14(11):1021-1031.
Wallace M, Green CR, Roberts LS, Lee YM, McCarville JL, Sanchez-Gurmaches J, Meurs N, Gengatharan JM, Hover JD, Phillips SA, Ciaraldi TP, Guertin DA, Cabrales P, Ayres JS, Nomura DK, Loomba R, Metallo CM. PMID: 30327559; PMCID: PMC6245668.
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PubMed Mentions:
58 Fields:
Translation:
AnimalsCells
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Cooperative Metabolic Adaptations in the Host Can Favor Asymptomatic Infection and Select for Attenuated Virulence in an Enteric Pathogen. Cell. 2018 09 20; 175(1):146-158.e15.
Sanchez KK, Chen GY, Schieber AMP, Redford SE, Shokhirev MN, Leblanc M, Lee YM, Ayres JS. PMID: 30100182; PMCID: PMC6447043.
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PubMed Mentions:
51 Fields:
Translation:
AnimalsCells
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When the Gut Gets Tough, the Enterocytes Get Going. Immunity. 2018 05 15; 48(5):837-839.
Chen GY, Ayres JS. PMID: 29768167.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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Decoding the intestinal epithelium cell by cell. Nat Immunol. 2018 01; 19(1):7-9.
Lee YM, Ayres JS. PMID: 29242547.
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PubMed Mentions:
1 Fields:
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Disease tolerance: concept and mechanisms. Curr Opin Immunol. 2018 02; 50:88-93.
McCarville JL, Ayres JS. PMID: 29253642; PMCID: PMC5884632.
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PubMed Mentions:
43 Fields:
Translation:
HumansAnimalsCells
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Resistance and tolerance defenses in cancer: Lessons from infectious diseases. Semin Immunol. 2017 08; 32:54-61.
Rao S, Ayres JS. PMID: 28865876.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
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NAIP-NLRC4 Inflammasomes Coordinate Intestinal Epithelial Cell Expulsion with Eicosanoid and IL-18 Release via Activation of Caspase-1 and -8. Immunity. 2017 04 18; 46(4):649-659.
Rauch I, Deets KA, Ji DX, von Moltke J, Tenthorey JL, Lee AY, Philip NH, Ayres JS, Brodsky IE, Gronert K, Vance RE. PMID: 28410991; PMCID: PMC5476318.
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PubMed Mentions:
159 Fields:
Translation:
AnimalsCells
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Pathogen-Mediated Inhibition of Anorexia Promotes Host Survival and Transmission. Cell. 2017 01 26; 168(3):503-516.e12.
Rao S, Schieber AMP, O'Connor CP, Leblanc M, Michel D, Ayres JS. PMID: 28129542; PMCID: PMC5324724.
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PubMed Mentions:
52 Fields:
Translation:
HumansAnimalsCells
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Microbes Dress for Success: Tolerance or Resistance? Trends Microbiol. 2017 01; 25(1):1-3.
Ayres JS. PMID: 27894645.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Thermoregulation as a disease tolerance defense strategy. Pathog Dis. 2016 12; 74(9).
Schieber AM, Ayres JS. PMID: 27815313; PMCID: PMC5975229.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimals
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Disease Tolerance Trick or Treat: Give Your Brain Something Good to Eat. Cell. 2016 Sep 08; 166(6):1368-1370.
Ayres JS. PMID: 27610563.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Cooperative Microbial Tolerance Behaviors in Host-Microbiota Mutualism. Cell. 2016 Jun 02; 165(6):1323-1331.
Ayres JS. PMID: 27259146; PMCID: PMC4903080.
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PubMed Mentions:
49 Fields:
Translation:
HumansAnimals
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Neuronal energy-sensing pathway promotes energy balance by modulating disease tolerance. Proc Natl Acad Sci U S A. 2016 Jun 07; 113(23):E3307-14.
Shen R, Wang B, Giribaldi MG, Ayres J, Thomas JB, Montminy M. PMID: 27208092; PMCID: PMC4988575.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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Disease tolerance mediated by microbiome E. coli involves inflammasome and IGF-1 signaling. Science. 2015 Oct 30; 350(6260):558-63.
Schieber AM, Lee YM, Chang MW, Leblanc M, Collins B, Downes M, Evans RM, Ayres JS. PMID: 26516283; PMCID: PMC4732872.
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PubMed Mentions:
79 Fields:
Translation:
AnimalsCells
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Inflammasome-microbiota interplay in host physiologies. Cell Host Microbe. 2013 Nov 13; 14(5):491-7.
Ayres JS. PMID: 24237695.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimals
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The ubiquitin ligase parkin mediates resistance to intracellular pathogens. Nature. 2013 Sep 26; 501(7468):512-6.
Manzanillo PS, Ayres JS, Watson RO, Collins AC, Souza G, Rae CS, Schneider DS, Nakamura K, Shiloh MU, Cox JS. PMID: 24005326; PMCID: PMC3886920.
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PubMed Mentions:
289 Fields:
Translation:
AnimalsCells
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Recognition of bacteria by inflammasomes. Annu Rev Immunol. 2013; 31:73-106.
von Moltke J, Ayres JS, Kofoed EM, Chavarría-Smith J, Vance RE. PMID: 23215645.
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PubMed Mentions:
182 Fields:
Translation:
HumansAnimalsCells
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Lethal inflammasome activation by a multidrug-resistant pathobiont upon antibiotic disruption of the microbiota. Nat Med. 2012 May; 18(5):799-806.
Ayres JS, Trinidad NJ, Vance RE. PMID: 22522562; PMCID: PMC3472005.
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PubMed Mentions:
105 Fields:
Translation:
AnimalsCells
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Cellular teamwork in antibacterial innate immunity. Nat Immunol. 2012 Jan 19; 13(2):115-7.
Ayres JS, Vance RE. PMID: 22261960.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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The circadian clock protein timeless regulates phagocytosis of bacteria in Drosophila. PLoS Pathog. 2012 Jan; 8(1):e1002445.
Stone EF, Fulton BO, Ayres JS, Pham LN, Ziauddin J, Shirasu-Hiza MM. PMID: 22253593; PMCID: PMC3257305.
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PubMed Mentions:
57 Fields:
Translation:
AnimalsCells
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Tolerance of infections. Annu Rev Immunol. 2012; 30:271-94.
Ayres JS, Schneider DS. PMID: 22224770.
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PubMed Mentions:
191 Fields:
Translation:
HumansAnimals
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The role of anorexia in resistance and tolerance to infections in Drosophila. PLoS Biol. 2009 Jul; 7(7):e1000150.
Ayres JS, Schneider DS. PMID: 19597539; PMCID: PMC2701602.
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PubMed Mentions:
134 Fields:
Translation:
AnimalsCells
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A signaling protease required for melanization in Drosophila affects resistance and tolerance of infections. PLoS Biol. 2008 Dec 09; 6(12):2764-73.
Ayres JS, Schneider DS. PMID: 19071960; PMCID: PMC2596860.
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PubMed Mentions:
109 Fields:
Translation:
AnimalsCells
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Two ways to survive infection: what resistance and tolerance can teach us about treating infectious diseases. Nat Rev Immunol. 2008 11; 8(11):889-95.
Schneider DS, Ayres JS. PMID: 18927577; PMCID: PMC4368196.
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PubMed Mentions:
329 Fields:
Translation:
HumansAnimals
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Pathogenesis of listeria-infected Drosophila wntD mutants is associated with elevated levels of the novel immunity gene edin. PLoS Pathog. 2008 Jul 25; 4(7):e1000111.
Gordon MD, Ayres JS, Schneider DS, Nusse R. PMID: 18654628; PMCID: PMC2453329.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Identification of Drosophila mutants altering defense of and endurance to Listeria monocytogenes infection. Genetics. 2008 Mar; 178(3):1807-15.
Ayres JS, Freitag N, Schneider DS. PMID: 18245331; PMCID: PMC2278058.
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PubMed Mentions:
71 Fields:
Translation:
AnimalsCells
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Interactions between circadian rhythm and immunity in Drosophila melanogaster. Curr Biol. 2007 May 15; 17(10):R353-5.
Shirasu-Hiza MM, Dionne MS, Pham LN, Ayres JS, Schneider DS. PMID: 17502084.
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PubMed Mentions:
55 Fields:
Translation:
AnimalsCells
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Drosophila eiger mutants are sensitive to extracellular pathogens. PLoS Pathog. 2007 Mar; 3(3):e41.
Schneider DS, Ayres JS, Brandt SM, Costa A, Dionne MS, Gordon MD, Mabery EM, Moule MG, Pham LN, Shirasu-Hiza MM. PMID: 17381241; PMCID: PMC1829408.
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PubMed Mentions:
55 Fields:
Translation:
AnimalsCells
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Genomic dissection of microbial pathogenesis in cultured Drosophila cells. Trends Microbiol. 2006 Mar; 14(3):101-4.
Ayres JS, Schneider DS. PMID: 16473012.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells