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Paired microbiome and metabolome analyses associate bile acid changes with colorectal cancer progression. Cell Rep. 2023 08 29; 42(8):112997.
Fu T, Huan T, Rahman G, Zhi H, Xu Z, Oh TG, Guo J, Coulter S, Tripathi A, Martino C, McCarville JL, Zhu Q, Cayabyab F, Low B, He M, Xing S, Vargas F, Yu RT, Atkins A, Liddle C, Ayres J, Raffatellu M, Dorrestein PC, Downes M, Knight R, Evans RM. PMID: 37611587.
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PubMed Mentions: Fields:
Translation:
Animals
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CD4+ T cells regulate sickness-induced anorexia and fat wasting during a chronic parasitic infection. Cell Rep. 2023 08 29; 42(8):112814.
Redford SE, Varanasi SK, Sanchez KK, Thorup NR, Ayres JS. PMID: 37490905.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Cooperation between physiological defenses and immune resistance produces asymptomatic carriage of a lethal bacterial pathogen. Sci Adv. 2023 Jun 23; 9(25):eadg8719.
Chen GY, Thorup NR, Miller AJ, Li YC, Ayres JS. PMID: 37352357; PMCID: PMC10289649.
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PubMed Mentions: Fields:
Translation:
Animals
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Cachexia: A systemic consequence of progressive, unresolved disease. Cell. 2023 04 27; 186(9):1824-1845.
Ferrer M, Anthony TG, Ayres JS, Biffi G, Brown JC, Caan BJ, Cespedes Feliciano EM, Coll AP, Dunne RF, Goncalves MD, Grethlein J, Heymsfield SB, Hui S, Jamal-Hanjani M, Lam JM, Lewis DY, McCandlish D, Mustian KM, O'Rahilly S, Perrimon N, White EP, Janowitz T. PMID: 37116469.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Age-dependent roles of cardiac remodeling in sepsis defense and pathogenesis. bioRxiv. 2023 Mar 15.
Sanchez KK, McCarville JL, Stengel SJ, Snyder JM, Williams AE, Ayres JS. PMID: 36993409; PMCID: PMC10055033.
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PubMed Mentions:
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Cooperation between physiological defenses and immune resistance produces asymptomatic carriage of a lethal bacterial pathogen. bioRxiv. 2023 Feb 26.
Chen GY, Thorup NR, Miller AJ, Li YC, Ayres JS. PMID: 36711884; PMCID: PMC9882269.
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PubMed Mentions:
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Chronic Leptin Deficiency Improves Tolerance of Physiological Damage and Host-Pathogen Cooperation during Yersinia pseudotuberculosis Infection. Infect Immun. 2022 09 15; 90(9):e0024222.
Sanchez KK, Troha K, Mu A, Redford SE, McCarville JL, Insenga A, Stengel S, Lee YM, Ayres JS. PMID: 35924898; PMCID: PMC9476980.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Virulence triggered allergies: Pseudomonas gets the Las laugh. Immunity. 2022 05 10; 55(5):824-826.
McCarville JL, Ayres JS. PMID: 35545032.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Adipose triglyceride lipase mediates lipolysis and lipid mobilization in response to iron-mediated negative energy balance. iScience. 2022 Mar 18; 25(3):103941.
Romero AR, Mu A, Ayres JS. PMID: 35265813; PMCID: PMC8899412.
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PubMed Mentions:
2
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Cooperative defenses during enteropathogenic infection. Curr Opin Microbiol. 2022 02; 65:123-130.
Troha K, Ayres JS. PMID: 34847524; PMCID: PMC8818259.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Microbiota control of maternal behavior regulates early postnatal growth of offspring. Sci Adv. 2021 01; 7(5).
Lee YM, Mu A, Wallace M, Gengatharan JM, Furst AJ, Bode L, Metallo CM, Ayres JS. PMID: 33514556; PMCID: PMC7846171.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Beyond tug-of-war: Iron metabolism in cooperative host-microbe interactions. PLoS Pathog. 2020 08; 16(8):e1008698.
Chen GY, Ayres JS. PMID: 32785251; PMCID: PMC7423093.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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A metabolic handbook for the COVID-19 pandemic. Nat Metab. 2020 07; 2(7):572-585.
Ayres JS. PMID: 32694793; PMCID: PMC7325641.
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PubMed Mentions:
131 Fields:
Translation:
HumansPHPublic Health
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Surviving COVID-19: A disease tolerance perspective. Sci Adv. 2020 05; 6(18):eabc1518.
Ayres JS. PMID: 32494691; PMCID: PMC7190329.
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PubMed Mentions:
20 Fields:
Translation:
HumansCellsPHPublic Health
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Microbiota Metabolites in Health and Disease. Annu Rev Immunol. 2020 04 26; 38:147-170.
McCarville JL, Chen GY, Cuevas VD, Troha K, Ayres JS. PMID: 32340573.
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PubMed Mentions:
54 Fields:
Translation:
HumansAnimals
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The Biology of Physiological Health. Cell. 2020 04 16; 181(2):250-269.
Ayres JS. PMID: 32302569; PMCID: PMC7409982.
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PubMed Mentions:
24 Fields:
Translation:
Humans
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Immunometabolism of infections. Nat Rev Immunol. 2020 02; 20(2):79-80.
Ayres JS. PMID: 31892735.
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PubMed Mentions:
31 Fields:
Translation:
HumansAnimalsCells
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Metabolic Adaptations to Infections at the Organismal Level. Trends Immunol. 2020 02; 41(2):113-125.
Troha K, Ayres JS. PMID: 31959515; PMCID: PMC7409656.
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PubMed Mentions:
28 Fields:
Translation:
Humans
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Host-Pathogen Relationship Advice: Fat Protects against a Broken Heart. Cell Metab. 2019 09 03; 30(3):409-411.
McCarville JL, Ayres JS. PMID: 31484052.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Enzyme promiscuity drives branched-chain fatty acid synthesis in adipose tissues. Nat Chem Biol. 2018 11; 14(11):1021-1031.
Wallace M, Green CR, Roberts LS, Lee YM, McCarville JL, Sanchez-Gurmaches J, Meurs N, Gengatharan JM, Hover JD, Phillips SA, Ciaraldi TP, Guertin DA, Cabrales P, Ayres JS, Nomura DK, Loomba R, Metallo CM. PMID: 30327559; PMCID: PMC6245668.
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PubMed Mentions:
67 Fields:
Translation:
AnimalsCells
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Cooperative Metabolic Adaptations in the Host Can Favor Asymptomatic Infection and Select for Attenuated Virulence in an Enteric Pathogen. Cell. 2018 09 20; 175(1):146-158.e15.
Sanchez KK, Chen GY, Schieber AMP, Redford SE, Shokhirev MN, Leblanc M, Lee YM, Ayres JS. PMID: 30100182; PMCID: PMC6447043.
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PubMed Mentions:
55 Fields:
Translation:
AnimalsCells
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When the Gut Gets Tough, the Enterocytes Get Going. Immunity. 2018 05 15; 48(5):837-839.
Chen GY, Ayres JS. PMID: 29768167.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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Decoding the intestinal epithelium cell by cell. Nat Immunol. 2018 01; 19(1):7-9.
Lee YM, Ayres JS. PMID: 29242547.
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PubMed Mentions:
2 Fields:
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Disease tolerance: concept and mechanisms. Curr Opin Immunol. 2018 02; 50:88-93.
McCarville JL, Ayres JS. PMID: 29253642; PMCID: PMC5884632.
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PubMed Mentions:
54 Fields:
Translation:
HumansAnimalsCells
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Resistance and tolerance defenses in cancer: Lessons from infectious diseases. Semin Immunol. 2017 08; 32:54-61.
Rao S, Ayres JS. PMID: 28865876.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
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NAIP-NLRC4 Inflammasomes Coordinate Intestinal Epithelial Cell Expulsion with Eicosanoid and IL-18 Release via Activation of Caspase-1 and -8. Immunity. 2017 04 18; 46(4):649-659.
Rauch I, Deets KA, Ji DX, von Moltke J, Tenthorey JL, Lee AY, Philip NH, Ayres JS, Brodsky IE, Gronert K, Vance RE. PMID: 28410991; PMCID: PMC5476318.
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PubMed Mentions:
176 Fields:
Translation:
AnimalsCells
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Pathogen-Mediated Inhibition of Anorexia Promotes Host Survival and Transmission. Cell. 2017 01 26; 168(3):503-516.e12.
Rao S, Schieber AMP, O'Connor CP, Leblanc M, Michel D, Ayres JS. PMID: 28129542; PMCID: PMC5324724.
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PubMed Mentions:
59 Fields:
Translation:
HumansAnimalsCells
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Microbes Dress for Success: Tolerance or Resistance? Trends Microbiol. 2017 01; 25(1):1-3.
Ayres JS. PMID: 27894645.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Thermoregulation as a disease tolerance defense strategy. Pathog Dis. 2016 12; 74(9).
Schieber AM, Ayres JS. PMID: 27815313; PMCID: PMC5975229.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimals
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Disease Tolerance Trick or Treat: Give Your Brain Something Good to Eat. Cell. 2016 Sep 08; 166(6):1368-1370.
Ayres JS. PMID: 27610563.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Cooperative Microbial Tolerance Behaviors in Host-Microbiota Mutualism. Cell. 2016 Jun 02; 165(6):1323-1331.
Ayres JS. PMID: 27259146; PMCID: PMC4903080.
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PubMed Mentions:
52 Fields:
Translation:
HumansAnimals
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Neuronal energy-sensing pathway promotes energy balance by modulating disease tolerance. Proc Natl Acad Sci U S A. 2016 Jun 07; 113(23):E3307-14.
Shen R, Wang B, Giribaldi MG, Ayres J, Thomas JB, Montminy M. PMID: 27208092; PMCID: PMC4988575.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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Disease tolerance mediated by microbiome E. coli involves inflammasome and IGF-1 signaling. Science. 2015 Oct 30; 350(6260):558-63.
Schieber AM, Lee YM, Chang MW, Leblanc M, Collins B, Downes M, Evans RM, Ayres JS. PMID: 26516283; PMCID: PMC4732872.
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PubMed Mentions:
82 Fields:
Translation:
AnimalsCells
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Inflammasome-microbiota interplay in host physiologies. Cell Host Microbe. 2013 Nov 13; 14(5):491-7.
Ayres JS. PMID: 24237695.
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PubMed Mentions:
22 Fields:
Translation:
HumansAnimals
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The ubiquitin ligase parkin mediates resistance to intracellular pathogens. Nature. 2013 Sep 26; 501(7468):512-6.
Manzanillo PS, Ayres JS, Watson RO, Collins AC, Souza G, Rae CS, Schneider DS, Nakamura K, Shiloh MU, Cox JS. PMID: 24005326; PMCID: PMC3886920.
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PubMed Mentions:
298 Fields:
Translation:
AnimalsCells
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Recognition of bacteria by inflammasomes. Annu Rev Immunol. 2013; 31:73-106.
von Moltke J, Ayres JS, Kofoed EM, Chavarría-Smith J, Vance RE. PMID: 23215645.
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PubMed Mentions:
191 Fields:
Translation:
HumansAnimalsCells
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Lethal inflammasome activation by a multidrug-resistant pathobiont upon antibiotic disruption of the microbiota. Nat Med. 2012 May; 18(5):799-806.
Ayres JS, Trinidad NJ, Vance RE. PMID: 22522562; PMCID: PMC3472005.
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PubMed Mentions:
110 Fields:
Translation:
AnimalsCells
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Cellular teamwork in antibacterial innate immunity. Nat Immunol. 2012 Jan 19; 13(2):115-7.
Ayres JS, Vance RE. PMID: 22261960.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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The circadian clock protein timeless regulates phagocytosis of bacteria in Drosophila. PLoS Pathog. 2012 Jan; 8(1):e1002445.
Stone EF, Fulton BO, Ayres JS, Pham LN, Ziauddin J, Shirasu-Hiza MM. PMID: 22253593; PMCID: PMC3257305.
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PubMed Mentions:
59 Fields:
Translation:
AnimalsCells
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Tolerance of infections. Annu Rev Immunol. 2012; 30:271-94.
Ayres JS, Schneider DS. PMID: 22224770.
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PubMed Mentions:
196 Fields:
Translation:
HumansAnimals
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The role of anorexia in resistance and tolerance to infections in Drosophila. PLoS Biol. 2009 Jul; 7(7):e1000150.
Ayres JS, Schneider DS. PMID: 19597539; PMCID: PMC2701602.
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PubMed Mentions:
136 Fields:
Translation:
AnimalsCells
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A signaling protease required for melanization in Drosophila affects resistance and tolerance of infections. PLoS Biol. 2008 Dec 09; 6(12):2764-73.
Ayres JS, Schneider DS. PMID: 19071960; PMCID: PMC2596860.
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PubMed Mentions:
113 Fields:
Translation:
AnimalsCells
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Two ways to survive infection: what resistance and tolerance can teach us about treating infectious diseases. Nat Rev Immunol. 2008 11; 8(11):889-95.
Schneider DS, Ayres JS. PMID: 18927577; PMCID: PMC4368196.
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PubMed Mentions:
343 Fields:
Translation:
HumansAnimals
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Pathogenesis of listeria-infected Drosophila wntD mutants is associated with elevated levels of the novel immunity gene edin. PLoS Pathog. 2008 Jul 25; 4(7):e1000111.
Gordon MD, Ayres JS, Schneider DS, Nusse R. PMID: 18654628; PMCID: PMC2453329.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Identification of Drosophila mutants altering defense of and endurance to Listeria monocytogenes infection. Genetics. 2008 Mar; 178(3):1807-15.
Ayres JS, Freitag N, Schneider DS. PMID: 18245331; PMCID: PMC2278058.
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PubMed Mentions:
72 Fields:
Translation:
AnimalsCells
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Interactions between circadian rhythm and immunity in Drosophila melanogaster. Curr Biol. 2007 May 15; 17(10):R353-5.
Shirasu-Hiza MM, Dionne MS, Pham LN, Ayres JS, Schneider DS. PMID: 17502084.
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PubMed Mentions:
56 Fields:
Translation:
AnimalsCells
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Drosophila eiger mutants are sensitive to extracellular pathogens. PLoS Pathog. 2007 Mar; 3(3):e41.
Schneider DS, Ayres JS, Brandt SM, Costa A, Dionne MS, Gordon MD, Mabery EM, Moule MG, Pham LN, Shirasu-Hiza MM. PMID: 17381241; PMCID: PMC1829408.
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PubMed Mentions:
58 Fields:
Translation:
AnimalsCells
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Genomic dissection of microbial pathogenesis in cultured Drosophila cells. Trends Microbiol. 2006 Mar; 14(3):101-4.
Ayres JS, Schneider DS. PMID: 16473012.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells