Mamata Sivagnanam

Title(s)	Clinical Professor, Pediatrics
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
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Research

Research Activities and Funding

Mutant EpCAMs role in Congenital Tufting Enteropathy
NIH/NIDDK R01DK107764Mar 1, 2016 - Feb 28, 2021
Role: Principal Investigator

Intestinal Epithelial Function in Congenital Tufting Enteropathy
NIH/NIDDK K08DK078672Aug 1, 2009 - Jul 31, 2014
Role: Principal Investigator

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Oral Ingestion of an Iron-Containing Hand Warmer in a Pediatric Patient. Wilderness Environ Med. 2024 Mar; 35(1):70-73. Hardin JR, Suzuki E, Seltzer JA, Suhandynata RT, Sivagnanam M, Lasoff DR. PMID: 38379476.

View in: PubMed Mentions: Fields:
Eme Emergency Medicine Med Medicine (General)
Translation:Humans
Pangenome comparison of Bacteroides fragilis genomospecies unveil genetic diversity and ecological insights. bioRxiv. 2023 Dec 21. Oles RE, Terrazas MC, Loomis LR, Hsu CY, Tribelhorn C, Ferre PB, Ea A, Bryant M, Young J, Carrow HC, Sandborn WJ, Dulai P, Sivagnanam M, Pride D, Knight R, Chu H. PMID: 38187556; PMCID: PMC10769428.

View in: PubMed Mentions:
The effect of a fennel seed extract on the STAT signaling and intestinal barrier function. PLoS One. 2022; 17(7):e0271045. Das B, Rabalais J, Kozan P, Lu T, Durali N, Okamoto K, McGeough MD, Lee BJ, Barrett KE, Marchelletta R, Sivagnanam M. PMID: 35802574; PMCID: PMC9269469.

View in: PubMed Mentions: 2 Fields:
Med Medicine (General)Sci Science
Translation:Humans Animals
Aberrant Epithelial Differentiation Contributes to Pathogenesis in a Murine Model of Congenital Tufting Enteropathy. Cell Mol Gastroenterol Hepatol. 2021; 12(4):1353-1371. Das B, Okamoto K, Rabalais J, Young JA, Barrett KE, Sivagnanam M. PMID: 34198013; PMCID: PMC8479479.

View in: PubMed Mentions: 5 Fields:
Gas Gastroenterology
Translation:Humans Animals Cells
Congenital Tufting Enteropathy: Biology, Pathogenesis and Mechanisms. J Clin Med. 2020 Dec 23; 10(1). Das B, Sivagnanam M. PMID: 33374714; PMCID: PMC7793535.

View in: PubMed Mentions: 8
Impact of COVID-19 on Pediatric Gastroenterology Fellow Training in North America. J Pediatr Gastroenterol Nutr. 2020 07; 71(1):6-11. Mallon D, Pohl JF, Phatak UP, Fernandes M, Rosen JM, Lusman SS, Nylund CM, Jump CS, Solomon AB, Srinath A, Singer A, Harb R, Rodriguez-Baez N, Whitfield Van Buren KL, Koyfman S, Bhatt R, Soler-Rodriguez DM, Sivagnanam M, Lee CK, NASPGHAN Training Committee COVID-19 Survey Working Group. PMID: 32369320; PMCID: PMC7273936.

View in: PubMed Mentions: 17 Fields:
Gas Gastroenterology Nut Nutritional Sciences Ped Pediatrics
Translation:Humans Cells PHPublic Health
Pediatric Gastroenterology, Hepatology, and Nutrition Entrustable Professional Activities: Development of an Assessment Tool and Curricular Resources. J Pediatr Gastroenterol Nutr. 2020 07; 71(1):e40-e45. Robson J, Lusman SS, Lee CK, Merves J, Middleton J, Perez ME, Desai NK, Sayej W, Sivagnanam M, Solomon AB, Colombo JM, Rosen JM, Van Buren KW, Brown JB, Turmelle YP, Cerezo CS, Loomes KM, Huang JS, Quiros-Tejeira RE, Benkov K, Leichtner A, Narkewicz MR, Weinstein T, Sauer CG. PMID: 32265411.

View in: PubMed Mentions: Fields:
Gas Gastroenterology Nut Nutritional Sciences Ped Pediatrics
Translation:Humans
Congenital Tufting Enteropathy-Associated Mutant of Epithelial Cell Adhesion Molecule Activates the Unfolded Protein Response in a Murine Model of the Disease. Cells. 2020 04 11; 9(4). Das B, Okamoto K, Rabalais J, Marchelletta RR, Barrett KE, Das S, Niwa M, Sivagnanam M. PMID: 32290509; PMCID: PMC7226999.

View in: PubMed Mentions: 3 Fields:
Bio Biophysics Cel Cell Biology Mol Molecular Biology
Translation:Humans Animals Cells
Enteroids expressing a disease-associated mutant of EpCAM are a model for congenital tufting enteropathy. Am J Physiol Gastrointest Liver Physiol. 2019 11 01; 317(5):G580-G591. Das B, Okamoto K, Rabalais J, Kozan PA, Marchelletta RR, McGeough MD, Durali N, Go M, Barrett KE, Das S, Sivagnanam M. PMID: 31433211; PMCID: PMC6879886.

View in: PubMed Mentions: 7 Fields:
Gas Gastroenterology Phy Physiology
Translation:Animals Cells
EPCAM mutation update: Variants associated with congenital tufting enteropathy and Lynch syndrome. Hum Mutat. 2019 02; 40(2):142-161. Pathak SJ, Mueller JL, Okamoto K, Das B, Hertecant J, Greenhalgh L, Cole T, Pinsk V, Yerushalmi B, Gurkan OE, Yourshaw M, Hernandez E, Oesterreicher S, Naik S, Sanderson IR, Axelsson I, Agardh D, Boland CR, Martin MG, Putnam CD, Sivagnanam M. PMID: 30461124; PMCID: PMC6328345.

View in: PubMed Mentions: 38 Fields:
Gen Genetics
Translation:Humans Cells
Biallelic Mismatch Repair Deficiency in an Adolescent Female. Case Rep Genet. 2018; 2018:8657823. Hildreth A, Valasek MA, Thung I, Savides T, Sivagnanam M, Ramamoorthy S, Huang SC. PMID: 30155321; PMCID: PMC6092986.

View in: PubMed Mentions: 3
Fever and Jaundice in a Previously Healthy Teenager. Clin Pediatr (Phila). 2016 10; 55(11):1081-4. Say DS, Chaparro J, Koning JL, Sivagnanam M. PMID: 27630008; PMCID: PMC5115630.

View in: PubMed Mentions: 3 Fields:
Ped Pediatrics
Translation:Humans Cells
Mutation of EpCAM leads to intestinal barrier and ion transport dysfunction. J Mol Med (Berl). 2015 May; 93(5):535-45. Kozan PA, McGeough MD, Peña CA, Mueller JL, Barrett KE, Marchelletta RR, Sivagnanam M. PMID: 25482158; PMCID: PMC4408367.

View in: PubMed Mentions: 26 Fields:
Gen Genetics Mol Molecular Biology
Translation:Animals Cells
Functional consequences of EpCam mutation in mice and men. Am J Physiol Gastrointest Liver Physiol. 2014 Feb 15; 306(4):G278-88. Mueller JL, McGeough MD, Peña CA, Sivagnanam M. PMID: 24337010; PMCID: PMC3920125.

View in: PubMed Mentions: 34 Fields:
Gas Gastroenterology Phy Physiology
Translation:Humans Animals Cells
Absence of cell-surface EpCAM in congenital tufting enteropathy. Hum Mol Genet. 2013 Jul 01; 22(13):2566-71. Schnell U, Kuipers J, Mueller JL, Veenstra-Algra A, Sivagnanam M, Giepmans BN. PMID: 23462293; PMCID: PMC3674798.

View in: PubMed Mentions: 28 Fields:
Gen Genetics Mol Molecular Biology
Translation:Humans Cells
Transcriptional Read-Through Induction Treatment Trial in Intestinal Failure Induced by an EpCAM Nonsense Mutation. Case Rep Med. 2012; 2012:173195. Sivagnanam M, Mueller JL, Szigeti R, Gopalakrishna GS, Kellermayer R. PMID: 22991516; PMCID: PMC3444051.

View in: PubMed Mentions: 3
Acute hepatotoxicity after ingestion of Morinda citrifolia (Noni Berry) juice in a 14-year-old boy. J Pediatr Gastroenterol Nutr. 2011 Feb; 52(2):222-4. Yu EL, Sivagnanam M, Ellis L, Huang JS. PMID: 21119544; PMCID: PMC5728648.

View in: PubMed Mentions: 12 Fields:
Gas Gastroenterology Nut Nutritional Sciences Ped Pediatrics
Translation:Humans Animals
Case of syndromic tufting enteropathy harbors SPINT2 mutation seen in congenital sodium diarrhea. Clin Dysmorphol. 2010 Jan; 19(1):48. Sivagnanam M, Janecke AR, Müller T, Heinz-Erian P, Taylor S, Bird LM. PMID: 20009592; PMCID: PMC6709868.

View in: PubMed Mentions: 16 Fields:
Ter Teratology
Translation:Humans
Further evidence for EpCAM as the gene for congenital tufting enteropathy. Am J Med Genet A. 2010 Jan; 152A(1):222-4. Sivagnanam M, Schaible T, Szigeti R, Byrd RH, Finegold MJ, Ranganathan S, Gopalakrishna GS, Tatevian N, Kellermayer R. PMID: 20034091; PMCID: PMC6691968.

View in: PubMed Mentions: 15 Fields:
Gen Genetics
Translation:Humans
Initial description of the human NLRP3 promoter. Genes Immun. 2008 Dec; 9(8):721-6. Anderson JP, Mueller JL, Misaghi A, Anderson S, Sivagnanam M, Kolodner RD, Hoffman HM. PMID: 18719602; PMCID: PMC4477692.

View in: PubMed Mentions: 22 Fields:
All Allergy and Immunology Mol Molecular Biology
Translation:Humans Cells
Identification of EpCAM as the gene for congenital tufting enteropathy. Gastroenterology. 2008 Aug; 135(2):429-37. Sivagnanam M, Mueller JL, Lee H, Chen Z, Nelson SF, Turner D, Zlotkin SH, Pencharz PB, Ngan BY, Libiger O, Schork NJ, Lavine JE, Taylor S, Newbury RO, Kolodner RD, Hoffman HM. PMID: 18572020; PMCID: PMC2574708.

View in: PubMed Mentions: 90 Fields:
Gas Gastroenterology
Translation:Humans Cells
A new syndrome of tufting enteropathy and choanal atresia, with ophthalmologic, hematologic and hair abnormalities. Clin Dysmorphol. 2007 Oct; 16(4):211-21. Bird LM, Sivagnanam M, Taylor S, Newbury RO. PMID: 17786112.

View in: PubMed Mentions: 13 Fields:
Ter Teratology
Translation:Humans