Savita Bhakta

Title(s)	Associate Clinical Professor, Psychiatry
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
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Overview

Interests

ERP, tolcapone, biomarkers, cognition

Research

Research Activities and Funding

Developing an ecologically valid virtual reality-EEG paradigm for biomarker assessment of procognitive treatment sensitivity in schizophrenia
NIH R21MH123707Aug 1, 2020 - Jul 31, 2022
Role: Principal Investigator

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.

Amphetamine alters an EEG marker of reward processing in humans and mice. Psychopharmacology (Berl). 2022 Mar; 239(3):923-933. Cavanagh JF, Olguin SL, Talledo JA, Kotz JE, Roberts BZ, Nungaray JA, Sprock J, Gregg D, Bhakta SG, Light GA, Swerdlow NR, Young JW, Brigman JL. PMID: 35132440; PMCID: PMC8891070.

View in: PubMed Mentions:
EEG reveals that dextroamphetamine improves cognitive control through multiple processes in healthy participants. Neuropsychopharmacology. 2022 04; 47(5):1029-1036. Bhakta SG, Cavanagh JF, Talledo JA, Kotz JE, Benster L, Roberts BZ, Nungaray JA, Brigman JL, Light GA, Swerdlow NR, Young JW. PMID: 35042948; PMCID: PMC8938448.

View in: PubMed Mentions:
Electrophysiological biomarkers of behavioral dimensions from cross-species paradigms. Transl Psychiatry. 2021 09 17; 11(1):482. Cavanagh JF, Gregg D, Light GA, Olguin SL, Sharp RF, Bismark AW, Bhakta SG, Swerdlow NR, Brigman JL, Young JW. PMID: 34535625; PMCID: PMC8448772.

View in: PubMed Mentions: Fields:
Psy Psychiatry
Translation:Animals
Auditory discrimination and frequency modulation learning in schizophrenia patients: amphetamine within-subject dose response and time course. Psychol Med. 2021 Apr 14; 1-9. Swerdlow NR, Bhakta SG, Talledo J, Benster L, Kotz J, Vinogradov S, Molina JL, Light GA. PMID: 33849683; PMCID: PMC8514598.

View in: PubMed Mentions: Fields:
Psy Psychology
Memantine effects on auditory discrimination and training in schizophrenia patients. Neuropsychopharmacology. 2020 12; 45(13):2180-2188. Swerdlow NR, Bhakta SG, Talledo J, Kotz J, Roberts BZ, Clifford RE, Thomas ML, Joshi YB, Molina JL, Light GA. PMID: 32961542; PMCID: PMC7784956.

View in: PubMed Mentions: 1 Fields:
Neu Neurology Psy Psychopharmacology
Translation:Humans
Memantine Effects on Electroencephalographic Measures of Putative Excitatory/Inhibitory Balance in Schizophrenia. Biol Psychiatry Cogn Neurosci Neuroimaging. 2020 06; 5(6):562-568. Molina JL, Voytek B, Thomas ML, Joshi YB, Bhakta SG, Talledo JA, Swerdlow NR, Light GA. PMID: 32340927; PMCID: PMC7286803.

View in: PubMed Mentions: 7 Fields:
Dia Diagnostic Imaging Neu Neurology Psy Psychiatry
Translation:Humans
Lessons learned by giving amphetamine to antipsychotic-medicated schizophrenia patients. Neuropsychopharmacology. 2019 12; 44(13):2277-2284. Swerdlow NR, Bhakta SG, Talledo J, Benster L, Kotz J, Lavadia M, Light GA. PMID: 31445502; PMCID: PMC6897898.

View in: PubMed Mentions: 1 Fields:
Neu Neurology Psy Psychopharmacology
Translation:Humans
Highs and lows of cannabinoid-dopamine interactions: effects of genetic variability and pharmacological modulation of catechol-O-methyl transferase on the acute response to delta-9-tetrahydrocannabinol in humans. Psychopharmacology (Berl). 2019 Nov; 236(11):3209-3219. Ranganathan M, De Aquino JP, Cortes-Briones JA, Radhakrishnan R, Pittman B, Bhakta S, D'Souza DC. PMID: 31187152.

View in: PubMed Mentions: 1 Fields:
Psy Psychopharmacology
Translation:Humans
Implementing a college mental health program - an overview of the first twelve months. J Am Coll Health. 2019 01; 67(1):27-31. Downs N, Alderman T, Bhakta S, Greenwood TA. PMID: 29601286; PMCID: PMC6336517.

View in: PubMed Mentions: 1 Fields:
Hea Health Services
Translation:Humans
Room to move: Plasticity in early auditory information processing and auditory learning in schizophrenia revealed by acute pharmacological challenge. Schizophr Res. 2018 09; 199:285-291. Swerdlow NR, Bhakta SG, Light GA. PMID: 29627173; PMCID: PMC6151271.

View in: PubMed Mentions: 16 Fields:
Psy Psychiatry
Translation:Humans Animals
Tolcapone-Enhanced Neurocognition in Healthy Adults: Neural Basis and Predictors. Int J Neuropsychopharmacol. 2017 12 01; 20(12):979-987. Bhakta SG, Light GA, Talledo JA, Balvaneda B, Hughes E, Alvarez A, Rana BK, Young JW, Swerdlow NR. PMID: 29020372; PMCID: PMC5716101.

View in: PubMed Mentions: 3 Fields:
Neu Neurology Psy Psychopharmacology
Translation:Humans
Effects of Amphetamine on Sensorimotor Gating and Neurocognition in Antipsychotic-Medicated Schizophrenia Patients. Neuropsychopharmacology. 2018 03; 43(4):708-717. Swerdlow NR, Bhakta SG, Talledo JA, Franz DM, Hughes EL, Rana BK, Light GA. PMID: 29154367; PMCID: PMC5809803.

View in: PubMed Mentions: 7 Fields:
Neu Neurology Psy Psychopharmacology
Translation:Humans
The 5 choice continuous performance test (5C-CPT): A novel tool to assess cognitive control across species. J Neurosci Methods. 2017 Dec 01; 292:53-60. Bhakta SG, Young JW. PMID: 28754432; PMCID: PMC5813688.

View in: PubMed Mentions: 4 Fields:
Neu Neurology
Translation:Humans Animals
Interactive effects of an N-methyl-d-aspartate receptor antagonist and a nicotinic acetylcholine receptor agonist on mismatch negativity: Implications for schizophrenia. Schizophr Res. 2018 01; 191:87-94. Hamilton HK, D'Souza DC, Ford JM, Roach BJ, Kort NS, Ahn KH, Bhakta S, Ranganathan M, Mathalon DH. PMID: 28711472; PMCID: PMC5745273.

View in: PubMed Mentions: 8 Fields:
Psy Psychiatry
Translation:Humans
Amphetamine Enhances Gains in Auditory Discrimination Training in Adult Schizophrenia Patients. Schizophr Bull. 2017 07 01; 43(4):872-880. Swerdlow NR, Tarasenko M, Bhakta SG, Talledo J, Alvarez AI, Hughes EL, Rana B, Vinogradov S, Light GA. PMID: 27798224; PMCID: PMC5472129.

View in: PubMed Mentions: 10 Fields:
Psy Psychiatry
Translation:Humans
Single-Dose Memantine Improves Cortical Oscillatory Response Dynamics in Patients with Schizophrenia. Neuropsychopharmacology. 2017 Dec; 42(13):2633-2639. Light GA, Zhang W, Joshi YB, Bhakta S, Talledo JA, Swerdlow NR. PMID: 28425497; PMCID: PMC5686499.

View in: PubMed Mentions: 16 Fields:
Neu Neurology Psy Psychopharmacology
Translation:Humans
Sensorimotor gating in healthy adults tested over a 15 year period. Biol Psychol. 2017 02; 123:177-186. Swerdlow NR, Bhakta SG, Rana BK, Kei J, Chou HH, Talledo JA. PMID: 28027936; PMCID: PMC5297597.

View in: PubMed Mentions: 2 Fields:
Psy Psychophysiology
Translation:Humans
Effects of acute memantine administration on MATRICS Consensus Cognitive Battery performance in psychosis: Testing an experimental medicine strategy. Psychopharmacology (Berl). 2016 06; 233(12):2399-410. Bhakta SG, Chou HH, Rana B, Talledo JA, Balvaneda B, Gaddis L, Light GA, Swerdlow NR. PMID: 27076209; PMCID: PMC5214934.

View in: PubMed Mentions: 9 Fields:
Psy Psychopharmacology
Translation:Humans
Memantine Effects On Sensorimotor Gating and Mismatch Negativity in Patients with Chronic Psychosis. Neuropsychopharmacology. 2016 Jan; 41(2):419-30. Swerdlow NR, Bhakta S, Chou HH, Talledo JA, Balvaneda B, Light GA. PMID: 26062785; PMCID: PMC5130118.

View in: PubMed Mentions: 34 Fields:
Neu Neurology Psy Psychopharmacology
Translation:Humans
Effects of nicotine on the neurophysiological and behavioral effects of ketamine in humans. Front Psychiatry. 2014; 5:3. Mathalon DH, Ahn KH, Perry EB, Cho HS, Roach BJ, Blais RK, Bhakta S, Ranganathan M, Ford JM, D'Souza DC. PMID: 24478731; PMCID: PMC3900858.

View in: PubMed Mentions: 15
Feasibility, safety, and efficacy of the combination of D-serine and computerized cognitive retraining in schizophrenia: an international collaborative pilot study. Neuropsychopharmacology. 2013 Feb; 38(3):492-503. D'Souza DC, Radhakrishnan R, Perry E, Bhakta S, Singh NM, Yadav R, Abi-Saab D, Pittman B, Chaturvedi SK, Sharma MP, Bell M, Andrade C. PMID: 23093223; PMCID: PMC3547200.

View in: PubMed Mentions: 24 Fields:
Neu Neurology Psy Psychopharmacology
Translation:Humans
The 3rd Schizophrenia International Research Society Conference, 14-18 April 2012, Florence, Italy: summaries of oral sessions. Schizophr Res. 2012 Oct; 141(1):e1-e24. Abbs B, Achalia RM, Adelufosi AO, Aktener AY, Beveridge NJ, Bhakta SG, Blackman RK, Bora E, Byun MS, Cabanis M, Carrion R, Castellani CA, Chow TJ, Dmitrzak-Weglarz M, Gayer-Anderson C, Gomes FV, Haut K, Hori H, Kantrowitz JT, Kishimoto T, Lee FH, Lin A, Palaniyappan L, Quan M, Rubio MD, Ruiz de Azúa S, Sahoo S, Strauss GP, Szczepankiewicz A, Thompson AD, Trotta A, Tully LM, Uchida H, Velthorst E, Young JW, O'Shea A, Delisi LE. PMID: 22910407; PMCID: PMC3877922.

View in: PubMed Mentions: 4 Fields:
Psy Psychiatry
Translation:Humans
The COMT Met158 allele and violence in schizophrenia: a meta-analysis. Schizophr Res. 2012 Sep; 140(1-3):192-7. Bhakta SG, Zhang JP, Malhotra AK. PMID: 22784685; PMCID: PMC4412346.

View in: PubMed Mentions: 15 Fields:
Psy Psychiatry
Translation:Humans
Nicotine fails to attenuate ketamine-induced cognitive deficits and negative and positive symptoms in humans: implications for schizophrenia. Biol Psychiatry. 2012 Nov 01; 72(9):785-94. D'Souza DC, Ahn K, Bhakta S, Elander J, Singh N, Nadim H, Jatlow P, Suckow RF, Pittman B, Ranganathan M. PMID: 22717030.

View in: PubMed Mentions: 19 Fields:
Psy Psychiatry Psy Psychophysiology
Translation:Humans
The safety of studies with intravenous Δ⁹-tetrahydrocannabinol in humans, with case histories. Psychopharmacology (Berl). 2012 Feb; 219(3):885-96. Carbuto M, Sewell RA, Williams A, Forselius-Bielen K, Braley G, Elander J, Pittman B, Schnakenberg A, Bhakta S, Perry E, Ranganathan M, D'Souza DC, Yale THC Study Group. PMID: 21845389.

View in: PubMed Mentions: 12 Fields:
Psy Psychopharmacology
Translation:Humans
Familial vulnerability to an unusual cognitive adverse effect of topiramate: Discussion of mechanisms. Indian J Psychiatry. 2010 Jul; 52(3):260-3. Andrade C, Bhakta SG, Fernandes PP. PMID: 21180413; PMCID: PMC2990828.

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The safety and efficacy of benzodiazepine-modified treatments as a special form of unmodified ECT. J ECT. 2010 Mar; 26(1):23-9. Shah N, Mahadeshwar S, Bhakta S, Bhirud M, Fernandes P, Andrade C. PMID: 20190597.

View in: PubMed Mentions: 6 Fields:
Neu Neurology The Therapeutics
Translation:Humans
Systematic enhancement of functioning as a therapeutic technique in conversion disorder. Indian J Psychiatry. 2009 Apr; 51(2):134-6. Andrade C, Bhakta SG, Singh NM. PMID: 19823633; PMCID: PMC2755160.

View in: PubMed Mentions:
Melatonin treatment of shoulder-and-neck dyskinesia possibly related to fluoxetine treatment. World J Biol Psychiatry. 2009; 10(4 Pt 3):1047-8. Bhakta SG, Andrade C. PMID: 19153888.

View in: PubMed Mentions: 1 Fields:
Psy Psychiatry
Translation:Humans
Effects of haloperidol on the behavioral, subjective, cognitive, motor, and neuroendocrine effects of Delta-9-tetrahydrocannabinol in humans. Psychopharmacology (Berl). 2008 Jul; 198(4):587-603. D'Souza DC, Braley G, Blaise R, Vendetti M, Oliver S, Pittman B, Ranganathan M, Bhakta S, Zimolo Z, Cooper T, Perry E. PMID: 18228005; PMCID: PMC2878815.

View in: PubMed Mentions: 39 Fields:
Psy Psychopharmacology
Translation:Humans PHPublic Health
Schizophrenia, osteoporosis, and an examination of the risk of fractures in patients receiving ECT. J ECT. 2007 Dec; 23(4):219-20. Andrade C, Bhakta SG, Singh NM. PMID: 18090690.

View in: PubMed Mentions: 1 Fields:
Neu Neurology The Therapeutics
Translation:Humans
Melatonin in schizophrenic outpatients with insomnia: a double-blind, placebo-controlled study. J Clin Psychiatry. 2007 Feb; 68(2):237-41. Suresh Kumar PN, Andrade C, Bhakta SG, Singh NM. PMID: 17335321.

View in: PubMed Mentions: 24 Fields:
Psy Psychiatry
Translation:Humans
Simultaneous true seizures and pseudoseizures. J Clin Psychiatry. 2006 Apr; 67(4):673. Andrade C, Singh NM, Bhakta SG. PMID: 16669735.

View in: PubMed Mentions: 2 Fields:
Psy Psychiatry
Translation:Humans
Controversy revisited: Selective serotonin reuptake inhibitors in paediatric depression. World J Biol Psychiatry. 2006; 7(4):251-60. Andrade C, Bhakta SG, Singh NM. PMID: 17071546.

View in: PubMed Mentions: 5 Fields:
Psy Psychiatry
Translation:Humans