Ester Kwon

Title(s)Associate Professor, Bioengineering
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Biography 
    Collapse Education and Training
    UC Berkeley, BerkeleyB.S.2004Bioengineering
    UC Berkeley, BerkeleyB.A.2004Molecular & Cell Biology
    University of Washington, SeattlePh.D.2010Bioengineering
    Massachusetts Institute of Technology, CambridgePostdoc

    Collapse Research 
    Collapse Research Activities and Funding
    Nanoscale biomaterials for targeted repair in traumatic brain injury
    NIH DP2NS111507Sep 30, 2018 - May 31, 2023
    Role: Principal Investigator
    Peptide-mediated delivery of siRNA for treatment of ovarian cancer
    NIH F32CA177094Feb 1, 2014 - Jan 31, 2017
    Role: Principal Investigator
    Dvelopment of multi-component peptide vehicles for in vivo neuronal gene therapy
    NIH F31NS064805Feb 23, 2009 - Feb 22, 2011
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Spatial Measurement and Inhibition of Calpain Activity in Traumatic Brain Injury with an Activity-Based Nanotheranostic Platform. ACS Nano. 2024 Sep 17; 18(37):25565-25576. Madias MI, Stessman LN, Warlof SJ, Kudryashev JA, Kwon EJ. PMID: 39236689; PMCID: PMC11411711.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    2. Author Correction: Large-scale evaluation of the ability of RNA-binding proteins to activate exon inclusion. Nat Biotechnol. 2024 Sep; 42(9):1467. Schmok JC, Jain M, Street LA, Tankka AT, Schafer D, Her HL, Elmsaouri S, Gosztyla ML, Boyle EA, Jagannatha P, Luo EC, Kwon EJ, Jovanovic M, Yeo GW. PMID: 38418649; PMCID: PMC11392803.
      View in: PubMed   Mentions:    Fields:    
    3. Robust genome and cell engineering via in vitro and in situ circularized RNAs. Nat Biomed Eng. 2024 Aug 26. Tong M, Palmer N, Dailamy A, Kumar A, Khaliq H, Han S, Finburgh E, Wing M, Hong C, Xiang Y, Miyasaki K, Portell A, Rainaldi J, Suhardjo A, Nourreddine S, Chew WL, Kwon EJ, Mali P. PMID: 39187662.
      View in: PubMed   Mentions: 1     Fields:    
    4. Mechanobiological Modulation of In Vitro Astrocyte Reactivity Using Variable Gel Stiffness. ACS Biomater Sci Eng. 2024 Jul 08; 10(7):4279-4296. C Benincasa J, Madias MI, Kandell RM, Delgado-Garcia LM, Engler AJ, Kwon EJ, Porcionatto MA. PMID: 38870483; PMCID: PMC11234334.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    5. Reprograming Clots for In Vivo Chemical Targeting in Traumatic Brain Injury. Adv Mater. 2024 Aug; 36(31):e2301738. Kandell RM, Wu JR, Kwon EJ. PMID: 38780012; PMCID: PMC11293973.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    6. Large-scale evaluation of the ability of RNA-binding proteins to activate exon inclusion. Nat Biotechnol. 2024 Sep; 42(9):1429-1441. Schmok JC, Jain M, Street LA, Tankka AT, Schafer D, Her HL, Elmsaouri S, Gosztyla ML, Boyle EA, Jagannatha P, Luo EC, Kwon EJ, Jovanovic M, Yeo GW. PMID: 38168984; PMCID: PMC11389820.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    7. Infusible Extracellular Matrix Biomaterial Promotes Vascular Integrity and Modulates the Inflammatory Response in Acute Traumatic Brain Injury. Adv Healthc Mater. 2023 10; 12(25):e2300782. Diaz MD, Kandell RM, Wu JR, Chen A, Christman KL, Kwon EJ. PMID: 37390094; PMCID: PMC10592293.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    8. Analysis of PEG-lipid anchor length on lipid nanoparticle pharmacokinetics and activity in a mouse model of traumatic brain injury. Biomater Sci. 2023 Jun 13; 11(12):4238-4253. Waggoner LE, Miyasaki KF, Kwon EJ. PMID: 36987922; PMCID: PMC10262813.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    9. An Activity-Based Nanosensor for Minimally-Invasive Measurement of Protease Activity in Traumatic Brain Injury. Adv Funct Mater. 2023 Jul 11; 33(28). Kudryashev JA, Madias MI, Kandell RM, Lin QX, Kwon EJ. PMID: 37873031; PMCID: PMC10586543.
      View in: PubMed   Mentions: 2  
    10. Engineered nanomaterials that exploit blood-brain barrier dysfunction for delivery to the brain. Adv Drug Deliv Rev. 2023 06; 197:114820. Wu JR, Hernandez Y, Miyasaki KF, Kwon EJ. PMID: 37054953.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    11. Intravascularly infused extracellular matrix as a biomaterial for targeting and treating inflamed tissues. Nat Biomed Eng. 2023 02; 7(2):94-109. Spang MT, Middleton R, Diaz M, Hunter J, Mesfin J, Banka A, Sullivan H, Wang R, Lazerson TS, Bhatia S, Corbitt J, D'Elia G, Sandoval-Gomez G, Kandell R, Vratsanos MA, Gnanasekaran K, Kato T, Igata S, Luo C, Osborn KG, Gianneschi NC, Eniola-Adefeso O, Cabrales P, Kwon EJ, Contijoch F, Reeves RR, DeMaria AN, Christman KL. PMID: 36581694; PMCID: PMC10166066.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    12. Heads Up! Interlinked Amyloidogenic and Axonal Transport Pathways in Concussion-Induced Neurodegeneration. Neurosci Insights. 2022; 17:26331055221129641. Almenar-Queralt A, Dos Santos Chaves R, Kwon EJ, Shah SB. PMID: 36274925; PMCID: PMC9580075.
      View in: PubMed   Mentions: 2  
    13. Porous Silicon Nanoparticles Targeted to the Extracellular Matrix for Therapeutic Protein Delivery in Traumatic Brain Injury. Bioconjug Chem. 2022 09 21; 33(9):1685-1697. Waggoner LE, Kang J, Zuidema JM, Vijayakumar S, Hurtado AA, Sailor MJ, Kwon EJ. PMID: 36017941; PMCID: PMC9492643.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    14. Targeting the Extracellular Matrix in Traumatic Brain Injury Increases Signal Generation from an Activity-Based Nanosensor. ACS Nano. 2021 12 28; 15(12):20504-20516. Kandell RM, Kudryashev JA, Kwon EJ. PMID: 34870408; PMCID: PMC8716428.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    15. Pharmacokinetic Analysis of Peptide-Modified Nanoparticles with Engineered Physicochemical Properties in a Mouse Model of Traumatic Brain Injury. AAPS J. 2021 08 16; 23(5):100. Waggoner LE, Madias MI, Hurtado AA, Kwon EJ. PMID: 34401968; PMCID: PMC8367032.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    16. Selective Permeabilization of Gram-Negative Bacterial Membranes Using Multivalent Peptide Constructs for Antibiotic Sensitization. ACS Infect Dis. 2021 04 09; 7(4):721-732. Chan LW, Hern KE, Ngambenjawong C, Lee K, Kwon EJ, Hung DT, Bhatia SN. PMID: 33689277; PMCID: PMC8043124.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    17. Peptide Spiders: Peptide-Polymer Conjugates to Traffic Nucleic Acids. Mol Pharm. 2020 09 08; 17(9):3633-3642. Kwon EJ, Ko H, Bhatia SN. PMID: 32786959; PMCID: PMC7986012.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    18. Nanomedicine for Acute Brain Injuries: Insight from Decades of Cancer Nanomedicine. Mol Pharm. 2021 02 01; 18(2):522-538. Kandell RM, Waggoner LE, Kwon EJ. PMID: 32584042; PMCID: PMC7759589.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    19. An Activity-Based Nanosensor for Traumatic Brain Injury. ACS Sens. 2020 03 27; 5(3):686-692. Kudryashev JA, Waggoner LE, Leng HT, Mininni NH, Kwon EJ. PMID: 32100994; PMCID: PMC7534893.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    20. Tumor-Targeting, MicroRNA-Silencing Porous Silicon Nanoparticles for Ovarian Cancer Therapy. ACS Appl Mater Interfaces. 2019 Jul 10; 11(27):23926-23937. Bertucci A, Kim KH, Kang J, Zuidema JM, Lee SH, Kwon EJ, Kim D, Howell SB, Ricci F, Ruoslahti E, Jang HJ, Sailor MJ. PMID: 31251556.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    21. iRGD-guided Tumor-penetrating Nanocomplexes for Therapeutic siRNA Delivery to Pancreatic Cancer. Mol Cancer Ther. 2018 11; 17(11):2377-2388. Lo JH, Hao L, Muzumdar MD, Raghavan S, Kwon EJ, Pulver EM, Hsu F, Aguirre AJ, Wolpin BM, Fuchs CS, Hahn WC, Jacks T, Bhatia SN. PMID: 30097486; PMCID: PMC6298224.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    22. Porous Silicon Nanoparticle Delivery of Tandem Peptide Anti-Infectives for the Treatment of Pseudomonas aeruginosa Lung Infections. Adv Mater. 2017 Sep; 29(35). Kwon EJ, Skalak M, Bertucci A, Braun G, Ricci F, Ruoslahti E, Sailor MJ, Bhatia SN. PMID: 28699173; PMCID: PMC5765747.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    23. Ultrasensitive tumour-penetrating nanosensors of protease activity. Nat Biomed Eng. 2017; 1. Kwon EJ, Dudani JS, Bhatia SN. PMID: 28970963; PMCID: PMC5621765.
      View in: PubMed   Mentions: 39     Fields:    
    24. Comparison of Modular PEG Incorporation Strategies for Stabilization of Peptide-siRNA Nanocomplexes. Bioconjug Chem. 2016 10 19; 27(10):2323-2331. Lo JH, Kwon EJ, Zhang AQ, Singhal P, Bhatia SN. PMID: 27583545; PMCID: PMC5410868.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimals
    25. Addendum: The schizophrenia risk gene product miR-137 alters presynaptic plasticity. Nat Neurosci. 2016 07 26; 19(8):1115. Siegert S, Seo J, Kwon EJ, Rudenko A, Cho S, Wang W, Flood Z, Martorell AJ, Ericsson M, Mungenast AE, Tsai LH. PMID: 27459408.
      View in: PubMed   Mentions: 1     Fields:    
    26. Neuron-Targeted Nanoparticle for siRNA Delivery to Traumatic Brain Injuries. ACS Nano. 2016 08 23; 10(8):7926-33. Kwon EJ, Skalak M, Lo Bu R, Bhatia SN. PMID: 27429164; PMCID: PMC5896006.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    27. Self-Sealing Porous Silicon-Calcium Silicate Core-Shell Nanoparticles for Targeted siRNA Delivery to the Injured Brain. Adv Mater. 2016 Sep; 28(36):7962-7969. Kang J, Joo J, Kwon EJ, Skalak M, Hussain S, She ZG, Ruoslahti E, Bhatia SN, Sailor MJ. PMID: 27383373; PMCID: PMC6274592.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    28. A peptide for targeted, systemic delivery of imaging and therapeutic compounds into acute brain injuries. Nat Commun. 2016 06 28; 7:11980. Mann AP, Scodeller P, Hussain S, Joo J, Kwon E, Braun GB, Mölder T, She ZG, Kotamraju VR, Ranscht B, Krajewski S, Teesalu T, Bhatia S, Sailor MJ, Ruoslahti E. PMID: 27351915; PMCID: PMC4931241.
      View in: PubMed   Mentions: 78     Fields:    Translation:HumansAnimalsCells
    29. Porous silicon-graphene oxide core-shell nanoparticles for targeted delivery of siRNA to the injured brain. Nanoscale Horiz. 2016 Sep 01; 1(5):407-414. Joo J, Kwon EJ, Kang J, Skalak M, Anglin EJ, Mann AP, Ruoslahti E, Bhatia SN, Sailor MJ. PMID: 29732165; PMCID: PMC5935492.
      View in: PubMed   Mentions: 23  
    30. Smart nanosystems: Bio-inspired technologies that interact with the host environment. Proc Natl Acad Sci U S A. 2015 Nov 24; 112(47):14460-6. Kwon EJ, Lo JH, Bhatia SN. PMID: 26598694; PMCID: PMC4664363.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    31. The schizophrenia risk gene product miR-137 alters presynaptic plasticity. Nat Neurosci. 2015 Jul; 18(7):1008-16. Siegert S, Seo J, Kwon EJ, Rudenko A, Cho S, Wang W, Flood Z, Martorell AJ, Ericsson M, Mungenast AE, Tsai LH. PMID: 26005852; PMCID: PMC4506960.
      View in: PubMed   Mentions: 117     Fields:    Translation:HumansAnimalsCells
    32. Drug-induced amplification of nanoparticle targeting to tumors. Nano Today. 2014 Oct; 9(5):550-559. Lin KY, Kwon EJ, Lo JH, Bhatia SN. PMID: 29731806; PMCID: PMC5935498.
      View in: PubMed   Mentions: 11  
    33. MicroRNAs in learning, memory, and neurological diseases. Learn Mem. 2012 Aug 16; 19(9):359-68. Wang W, Kwon EJ, Tsai LH. PMID: 22904366.
      View in: PubMed   Mentions: 105     Fields:    Translation:Humans
    34. A truncated HGP peptide sequence that retains endosomolytic activity and improves gene delivery efficiencies. Mol Pharm. 2010 Aug 02; 7(4):1260-5. Kwon EJ, Liong S, Pun SH. PMID: 20476763; PMCID: PMC3018701.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    35. Targeted nonviral delivery vehicles to neural progenitor cells in the mouse subventricular zone. Biomaterials. 2010 Mar; 31(8):2417-24. Kwon EJ, Lasiene J, Jacobson BE, Park IK, Horner PJ, Pun SH. PMID: 20004466; PMCID: PMC2813955.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    36. Application of an HIV gp41-derived peptide for enhanced intracellular trafficking of synthetic gene and siRNA delivery vehicles. Bioconjug Chem. 2008 Apr; 19(4):920-7. Kwon EJ, Bergen JM, Pun SH. PMID: 18376855.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    37. Application of an environmentally sensitive fluorophore for rapid analysis of the binding and internalization efficiency of gene carriers. Bioconjug Chem. 2008 Jan; 19(1):377-84. Bergen JM, Kwon EJ, Shen TW, Pun SH. PMID: 18062659; PMCID: PMC2547138.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
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