Albert Chen

Title(s)	Project Scientist, Bioengineering
School	Vc-academic Affairs
Address	9500 Gilman Drive # La Jolla CA 92093
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Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Impact insertion of osteochondral grafts: Interference fit and central graft reduction affect biomechanics and cartilage damage. J Orthop Res. 2018 01; 36(1):377-386. Su AW, Chen Y, Wailes DH, Wong VW, Cai S, Chen AC, Bugbee WD, Sah RL. PMID: 28682003; PMCID: PMC5756525.

View in: PubMed Mentions: 4 Fields:
Ort Orthopedics
Translation:Animals Cells
Ex vivo loading of trussed implants for spine fusion induces heterogeneous strains consistent with homeostatic bone mechanobiology. J Biomech. 2016 12 08; 49(16):4090-4097. Caffrey JP, Cory E, Wong VW, Masuda K, Chen AC, Hunt JP, Ganey TM, Sah RL. PMID: 27836500; PMCID: PMC5164966.

View in: PubMed Mentions: 3 Fields:
Phy Physiology
Translation:Humans
Hyaluronan concentration and size distribution in human knee synovial fluid: variations with age and cartilage degeneration. Arthritis Res Ther. 2016 Jan 21; 18:18. Temple-Wong MM, Ren S, Quach P, Hansen BC, Chen AC, Hasegawa A, D'Lima DD, Koziol J, Masuda K, Lotz MK, Sah RL. PMID: 26792492; PMCID: PMC4721052.

View in: PubMed Mentions: 40 Fields:
Rhe Rheumatology
Translation:Humans
Addition of Mesenchymal Stem Cells to Autologous Platelet-Enhanced Fibrin Scaffolds in Chondral Defects: Does It Enhance Repair? J Bone Joint Surg Am. 2016 Jan 06; 98(1):23-34. Goodrich LR, Chen AC, Werpy NM, Williams AA, Kisiday JD, Su AW, Cory E, Morley PS, McIlwraith CW, Sah RL, Chu CR. PMID: 26738900; PMCID: PMC4697360.

View in: PubMed Mentions: 22 Fields:
Gen General Surgery Ort Orthopedics
Translation:Humans Animals Cells
Matrix stiffness drives epithelial-mesenchymal transition and tumour metastasis through a TWIST1-G3BP2 mechanotransduction pathway. Nat Cell Biol. 2015 May; 17(5):678-88. Wei SC, Fattet L, Tsai JH, Guo Y, Pai VH, Majeski HE, Chen AC, Sah RL, Taylor SS, Engler AJ, Yang J. PMID: 25893917; PMCID: PMC4452027.

View in: PubMed Mentions: 407 Fields:
Cel Cell Biology
Translation:Humans Animals Cells
Mechanical evaluation of a tissue-engineered zone of calcification in a bone-hydrogel osteochondral construct. Comput Methods Biomech Biomed Engin. 2015; 18(3):332-7. Hollenstein J, Terrier A, Cory E, Chen AC, Sah RL, Pioletti DP. PMID: 23706035; PMCID: PMC4732526.

View in: PubMed Mentions: 7 Fields:
Bio Biomedical Engineering Phy Physiology
Translation:Animals
In vivo efficacy of fresh versus frozen osteochondral allografts in the goat at 6 months is associated with PRG4 secretion. J Orthop Res. 2013 Jun; 31(6):880-6. Pallante-Kichura AL, Chen AC, Temple-Wong MM, Bugbee WD, Sah RL. PMID: 23362152; PMCID: PMC4076778.

View in: PubMed Mentions: 6 Fields:
Ort Orthopedics
Translation:Animals Cells
Treatment of articular cartilage defects in the goat with frozen versus fresh osteochondral allografts: effects on cartilage stiffness, zonal composition, and structure at six months. J Bone Joint Surg Am. 2012 Nov 07; 94(21):1984-95. Pallante AL, Görtz S, Chen AC, Healey RM, Chase DC, Ball ST, Amiel D, Sah RL, Bugbee WD. PMID: 23138239; PMCID: PMC3489067.

View in: PubMed Mentions: 25 Fields:
Gen General Surgery Ort Orthopedics
Translation:Animals
Tmod1 and CP49 synergize to control the fiber cell geometry, transparency, and mechanical stiffness of the mouse lens. PLoS One. 2012; 7(11):e48734. Gokhin DS, Nowak RB, Kim NE, Arnett EE, Chen AC, Sah RL, Clark JI, Fowler VM. PMID: 23144950; PMCID: PMC3492431.

View in: PubMed Mentions: 41 Fields:
Med Medicine (General)Sci Science
Translation:Animals Cells
Association of 3-Dimensional Cartilage and Bone Structure with Articular Cartilage Properties in and Adjacent to Autologous Osteochondral Grafts after 6 and 12 months in a Goat Model. Cartilage. 2012 Jul 01; 3(3). Chan EF, Liu IL, Semler EJ, Aberman HM, Simon TM, Chen AC, Truncale KG, Sah RL. PMID: 24224069; PMCID: PMC3818730.

View in: PubMed Mentions: 10 Fields:
Bio Biomedical Engineering Ort Orthopedics Tra Transplantation
Cartilage-like mechanical properties of poly (ethylene glycol)-diacrylate hydrogels. Biomaterials. 2012 Oct; 33(28):6682-90. Nguyen QT, Hwang Y, Chen AC, Varghese S, Sah RL. PMID: 22749448; PMCID: PMC3572364.

View in: PubMed Mentions: 50 Fields:
Bio Biomedical Engineering
The in vivo performance of osteochondral allografts in the goat is diminished with extended storage and decreased cartilage cellularity. Am J Sports Med. 2012 Aug; 40(8):1814-23. Pallante AL, Chen AC, Ball ST, Amiel D, Masuda K, Sah RL, Bugbee WD. PMID: 22707746; PMCID: PMC4041579.

View in: PubMed Mentions: 33 Fields:
Spo Sports Medicine
Translation:Animals Cells
Compaction enhances extracellular matrix content and mechanical properties of tissue-engineered cartilaginous constructs. Tissue Eng Part A. 2012 Jun; 18(11-12):1151-60. Han EH, Ge C, Chen AC, Schumacher BL, Sah RL. PMID: 22372815; PMCID: PMC3360506.

View in: PubMed Mentions: 1 Fields:
Bio Biotechnology His Histology
Translation:Animals Cells
In vitro articular cartilage growth with sequential application of IGF-1 and TGF-β1 enhances volumetric growth and maintains compressive properties. J Biomech Eng. 2012 Mar; 134(3):031001. Balcom NT, Berg-Johansen B, Dills KJ, Van Donk JR, Williams GM, Chen AC, Hazelwood SJ, Sah RL, Klisch SM. PMID: 22482681; PMCID: PMC3689422.

View in: PubMed Mentions: 3 Fields:
Bio Biomedical Engineering
Translation:Animals
Effect of initial cell seeding density on 3D-engineered silk fibroin scaffolds for articular cartilage tissue engineering. Biomaterials. 2011 Dec; 32(34):8927-37. Talukdar S, Nguyen QT, Chen AC, Sah RL, Kundu SC. PMID: 21906805; PMCID: PMC3183393.

View in: PubMed Mentions: 30 Fields:
Bio Biomedical Engineering
Translation:Animals Cells
Potential of 3-D tissue constructs engineered from bovine chondrocytes/silk fibroin-chitosan for in vitro cartilage tissue engineering. Biomaterials. 2011 Sep; 32(25):5773-81. Bhardwaj N, Nguyen QT, Chen AC, Kaplan DL, Sah RL, Kundu SC. PMID: 21601277; PMCID: PMC3110545.

View in: PubMed Mentions: 38 Fields:
Bio Biomedical Engineering
Translation:Animals Cells
Insulin-like growth factor-I and growth differentiation factor-5 promote the formation of tissue-engineered human nasal septal cartilage. Tissue Eng Part C Methods. 2010 Oct; 16(5):1213-21. Alexander TH, Sage AB, Chen AC, Schumacher BL, Shelton E, Masuda K, Sah RL, Watson D. PMID: 20178406; PMCID: PMC2943402.

View in: PubMed Mentions: 11 Fields:
Bio Biotechnology His Histology
Translation:Humans
Tissue engineering by molecular disassembly and reassembly: biomimetic retention of mechanically functional aggrecan in hydrogel. Tissue Eng Part C Methods. 2010 Dec; 16(6):1471-9. Han EH, Wilensky LM, Schumacher BL, Chen AC, Masuda K, Sah RL. PMID: 20486781; PMCID: PMC2988632.

View in: PubMed Mentions: 5 Fields:
Bio Biotechnology His Histology
Translation:Animals Cells
Differential regulation of immature articular cartilage compressive moduli and Poisson's ratios by in vitro stimulation with IGF-1 and TGF-beta1. J Biomech. 2010 Sep 17; 43(13):2501-7. Williams GM, Dills KJ, Flores CR, Stender ME, Stewart KM, Nelson LM, Chen AC, Masuda K, Hazelwood SJ, Klisch SM, Sah RL. PMID: 20570267; PMCID: PMC2937078.

View in: PubMed Mentions: 7 Fields:
Phy Physiology
Translation:Animals
Can osteochondral grafting be augmented with microfracture in an extended-size lesion of articular cartilage? Am J Sports Med. 2010 Jul; 38(7):1316-23. Lane JG, Healey RM, Chen AC, Sah RL, Amiel D. PMID: 20400750; PMCID: PMC4111625.

View in: PubMed Mentions: 12 Fields:
Spo Sports Medicine
Translation:Animals Cells
Topographic Patterns of Cartilage Lesions in Knee Osteoarthritis. Cartilage. 2010 Jan; 1(1):10-19. Bae WC, Payanal MM, Chen AC, Hsieh-Bonassera ND, Ballard BL, Lotz MK, Coutts RD, Bugbee WD, Sah RL. PMID: 20664706; PMCID: PMC2909594.

View in: PubMed Mentions: 15 Fields:
Bio Biomedical Engineering Ort Orthopedics Tra Transplantation
Expansion and redifferentiation of chondrocytes from osteoarthritic cartilage: cells for human cartilage tissue engineering. Tissue Eng Part A. 2009 Nov; 15(11):3513-23. Hsieh-Bonassera ND, Wu I, Lin JK, Schumacher BL, Chen AC, Masuda K, Bugbee WD, Sah RL. PMID: 19456239; PMCID: PMC2792054.

View in: PubMed Mentions: 21 Fields:
Bio Biotechnology His Histology
Translation:Humans Cells
Chondrocyte viability is higher after prolonged storage at 37 degrees C than at 4 degrees C for osteochondral grafts. Am J Sports Med. 2009 Nov; 37 Suppl 1:24S-32S. Pallante AL, Bae WC, Chen AC, Görtz S, Bugbee WD, Sah RL. PMID: 19861697; PMCID: PMC2858049.

View in: PubMed Mentions: 50 Fields:
Spo Sports Medicine
Translation:Animals Cells
Articular cartilage mechanical and biochemical property relations before and after in vitro growth. J Biomech. 2007; 40(16):3607-14. Ficklin T, Thomas G, Barthel JC, Asanbaeva A, Thonar EJ, Masuda K, Chen AC, Sah RL, Davol A, Klisch SM. PMID: 17628568; PMCID: PMC2175072.

View in: PubMed Mentions: 28 Fields:
Phy Physiology
Translation:Animals
Short-term retention of labeled chondrocyte subpopulations in stratified tissue-engineered cartilaginous constructs implanted in vivo in mini-pigs. Tissue Eng. 2007 Jul; 13(7):1525-37. Chawla K, Klein TJ, Schumacher BL, Jadin KD, Shah BH, Nakagawa K, Wong VW, Chen AC, Masuda K, Sah RL. PMID: 17532744.

View in: PubMed Mentions: 16 Fields:
Bio Biotechnology His Histology
Translation:Animals Cells
Effect of impact on chondrocyte viability during insertion of human osteochondral grafts. J Bone Joint Surg Am. 2006 Sep; 88(9):1934-43. Borazjani BH, Chen AC, Bae WC, Patil S, Sah RL, Firestein GS, Bugbee WD. PMID: 16951108.

View in: PubMed Mentions: 33 Fields:
Gen General Surgery Ort Orthopedics
Translation:Humans Cells
Compressive biomechanical properties of human nasal septal cartilage. Am J Rhinol. 2006 Sep-Oct; 20(5):496-501. Richmon JD, Sage A, Wong WV, Chen AC, Sah RL, Watson D, Watston D. PMID: 17063745.

View in: PubMed Mentions: 26 Fields:
Oto Otolaryngology
Translation:Humans Cells
Tensile biomechanical properties of human nasal septal cartilage. Am J Rhinol. 2005 Nov-Dec; 19(6):617-22. Richmon JD, Sage AB, Wong VW, Chen AC, Pan C, Sah RL, Watson D. PMID: 16402652.

View in: PubMed Mentions: 20 Fields:
Oto Otolaryngology
Translation:Humans
Evaluation of subchondral bone mineral density associated with articular cartilage structure and integrity in healthy equine joints with different functional demands. Am J Vet Res. 2005 Oct; 66(10):1823-9. Lewis CW, Williamson AK, Chen AC, Bae WC, Temple MM, Wong WV, Nugent GE, James SP, Wheeler DL, Sah RL, Kawcak CE. PMID: 16273917.

View in: PubMed Mentions: Fields:
Vet Veterinary Medicine
Translation:Animals
Analysis of stored osteochondral allografts at the time of surgical implantation. Am J Sports Med. 2005 Oct; 33(10):1479-84. Allen RT, Robertson CM, Pennock AT, Bugbee WD, Harwood FL, Wong VW, Chen AC, Sah RL, Amiel D. PMID: 16009984.

View in: PubMed Mentions: 30 Fields:
Spo Sports Medicine
Translation:Humans Cells
Proteoglycan 4 (PRG4) synthesis and immunolocalization in bovine meniscus. J Orthop Res. 2005 May; 23(3):562-8. Schumacher BL, Schmidt TA, Voegtline MS, Chen AC, Sah RL. PMID: 15885476.

View in: PubMed Mentions: 31 Fields:
Ort Orthopedics
Translation:Animals
Biomechanical assessment of tissue retrieved after in vivo cartilage defect repair: tensile modulus of repair tissue and integration with host cartilage. J Biomech. 2006; 39(1):138-46. Gratz KR, Wong VW, Chen AC, Fortier LA, Nixon AJ, Sah RL. PMID: 16271598.

View in: PubMed Mentions: 13 Fields:
Phy Physiology
Translation:Animals Cells
Site- and exercise-related variation in structure and function of cartilage from equine distal metacarpal condyle. Osteoarthritis Cartilage. 2004 Oct; 12(10):826-33. Nugent GE, Law AW, Wong EG, Temple MM, Bae WC, Chen AC, Kawcak CE, Sah RL. PMID: 15450533.

View in: PubMed Mentions: 6 Fields:
Ort Orthopedics Rhe Rheumatology
Translation:Animals CTClinical Trials
Follow-up of osteochondral plug transfers in a goat model: a 6-month study. Am J Sports Med. 2004 Sep; 32(6):1440-50. Lane JG, Massie JB, Ball ST, Amiel ME, Chen AC, Bae WC, Sah RL, Amiel D. PMID: 15310569.

View in: PubMed Mentions: 40 Fields:
Spo Sports Medicine
Translation:Animals Cells
The effects of storage on fresh human osteochondral allografts. Clin Orthop Relat Res. 2004 Jan; (418):246-52. Ball ST, Amiel D, Williams SK, Tontz W, Chen AC, Sah RL, Bugbee WD. PMID: 15043126.

View in: PubMed Mentions: 46 Fields:
Ort Orthopedics
Translation:Humans Cells
Mechanical characterization of native and tissue-engineered cartilage. Methods Mol Med. 2004; 101:157-90. Chen AC, Klisch SM, Bae WC, Temple MM, McGowan KB, Gratz KR, Schumacher BL, Sah RL. PMID: 15299215.

View in: PubMed Mentions: 5 Fields:
Mol Molecular Biology
Translation:Humans Animals
Prolonged storage effects on the articular cartilage of fresh human osteochondral allografts. J Bone Joint Surg Am. 2003 Nov; 85(11):2111-20. Williams SK, Amiel D, Ball ST, Allen RT, Wong VW, Chen AC, Sah RL, Bugbee WD. PMID: 14630839.

View in: PubMed Mentions: 80 Fields:
Gen General Surgery Ort Orthopedics
Translation:Humans Cells
Tensile mechanical properties of bovine articular cartilage: variations with growth and relationships to collagen network components. J Orthop Res. 2003 Sep; 21(5):872-80. Williamson AK, Chen AC, Masuda K, Thonar EJ, Sah RL. PMID: 12919876.

View in: PubMed Mentions: 85 Fields:
Ort Orthopedics
Translation:Animals
Adhesion of perichondrial cells to a polylactic acid scaffold. J Orthop Res. 2003 Jul; 21(4):584-9. Giurea A, Klein TJ, Chen AC, Goomer RS, Coutts RD, Akeson WH, Amiel D, Sah RL. PMID: 12798055.

View in: PubMed Mentions: 1 Fields:
Ort Orthopedics
Translation:Animals Cells
Induction of advanced glycation end products and alterations of the tensile properties of articular cartilage. Arthritis Rheum. 2002 Dec; 46(12):3212-7. Chen AC, Temple MM, Ng DM, Verzijl N, DeGroot J, TeKoppele JM, Sah RL. PMID: 12483725.

View in: PubMed Mentions: 33 Fields:
Rhe Rheumatology
Translation:Animals
Static and dynamic compression modulate matrix metabolism in tissue engineered cartilage. J Orthop Res. 2002 Jul; 20(4):842-8. Davisson T, Kunig S, Chen A, Sah R, Ratcliffe A. PMID: 12168676.

View in: PubMed Mentions: 50 Fields:
Ort Orthopedics
Translation:Animals Cells