Terkeltaub, Robert Dr.

Title(s)Professor, Medicine
Address9500 Gilman Drive #9111K
La Jolla CA 92093
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    Collapse Biography 
    Collapse Education and Training
    McGill University, Montreal, CanadaMD1976Medicine
    McGill University, Montreal, CanadaDCS1972Biology

    Collapse Overview 
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    Research Interests
    Cartilage nucleotide metabolism and disease; the regulation of proinflammatory cytokine expression in macrophages.

    Collapse Research 
    Collapse Research Activities and Funding
    Novel Synovial Role in Pathogenesis of Gout
    NIH/NIAMS R21AR075990Aug 1, 2019 - Jul 31, 2021
    Role: Principal Investigator
    Rheumatic Diseases Research Training Grant
    NIH/NIAMS T32AR064194May 9, 2013 - Apr 30, 2024
    Role: Principal Investigator
    Innate Inflammation in Osteoarthritis
    VA I01BX001660Apr 1, 2012 - Mar 31, 2021
    Role: Principal Investigator
    Transglutaminase 2 in Arterial Calcification and Atherosclerosis
    NIH/NHLBI R01HL087252May 15, 2008 - Feb 28, 2012
    Role: Principal Investigator
    Chondrocyte S100/Calgranulins and RAGE in Osteoarthritis
    NIH/NIAMS R01AR054135Jun 1, 2006 - May 31, 2010
    Role: Principal Investigator
    ANK and Joint Ankylosis in Spondylitis
    NIH/NIAMS R01AR049366Jan 1, 2005 - Nov 30, 2008
    Role: Principal Investigator
    Molecular Mechanisms in Arterial Calcification
    NIH/NHLBI R01HL077360Jul 1, 2004 - Jun 30, 2014
    Role: Principal Investigator
    NIH/NIAMS R01AR047347Apr 6, 2001 - Jan 31, 2006
    Role: Principal Investigator
    NIH/NIAMS P60AR040770Aug 1, 1991 - Mar 6, 1997
    Role: Co-Investigator
    Studies of Joint Aging and Osteoarthritis
    NIH P01AG007996Dec 1, 1988 - Apr 30, 2017
    Role: Co-Investigator
    NIH/NIDDK R01DK036702Jul 1, 1985 - Jun 30, 1996
    Role: Principal Investigator
    NIH/NIADDK R23AM036702Jul 1, 1985 - Jun 30, 1988
    Role: Principal Investigator
    NIH/NIDDK R23DK036702Jul 1, 1985 - Jun 30, 1988
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Differential DNA Methylation of Networked Signaling, Transcriptional, Innate and Adaptive Immunity, and Osteoclastogenesis Genes and Pathways in Gout. Arthritis Rheumatol. 2020 May; 72(5):802-814. Wang Z, Zhao Y, Phipps-Green A, Liu-Bryan R, Ceponis A, Boyle DL, Wang J, Merriman TR, Wang W, Terkeltaub R. PMID: 31738005.
      View in: PubMed   Mentions:    Fields:    
    2. Exploration of metformin as novel therapy for osteoarthritis: preventing cartilage degeneration and reducing pain behavior. Arthritis Res Ther. 2020 02 22; 22(1):34. Li H, Ding X, Terkeltaub R, Lin H, Zhang Y, Zhou B, He K, Li K, Liu Z, Wei J, Yang Y, Xie H, Zeng C, Lei G. PMID: 32087740.
      View in: PubMed   Mentions:    Fields:    
    3. Patients Prescribed Anakinra for Acute Gout Have Baseline Increased Burden of Hyperuricemia, Tophi, and Comorbidities, and Ultimate All-Cause Mortality. Clin Med Insights Arthritis Musculoskelet Disord. 2019; 12:1179544119890853. Sharma E, Pedersen B, Terkeltaub R. PMID: 31839715.
      View in: PubMed   Mentions:
    4. Reply. Arthritis Rheumatol. 2019 11; 71(11):1967-1968. Choi H, Neogi T, Stamp L, Dalbeth N, Terkeltaub R. PMID: 31379125.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Gout, Hyperuricaemia and Crystal-Associated Disease Network (G-CAN) consensus statement regarding labels and definitions of disease states of gout. Ann Rheum Dis. 2019 11; 78(11):1592-1600. Bursill D, Taylor WJ, Terkeltaub R, Abhishek A, So AK, Vargas-Santos AB, Gaffo AL, Rosenthal A, Tausche AK, Reginato A, Manger B, Sciré C, Pineda C, van Durme C, Lin CT, Yin C, Albert DA, Biernat-Kaluza E, Roddy E, Pascual E, Becce F, Perez-Ruiz F, Sivera F, Lioté F, Schett G, Nuki G, Filippou G, McCarthy G, da Rocha Castelar Pinheiro G, Ea HK, Tupinambá HA, Yamanaka H, Choi HK, Mackay J, ODell JR, Vázquez Mellado J, Singh JA, Fitzgerald JD, Jacobsson LTH, Joosten L, Harrold LR, Stamp L, Andrés M, Gutierrez M, Kuwabara M, Dehlin M, Janssen M, Doherty M, Hershfield MS, Pillinger M, Edwards NL, Schlesinger N, Kumar N, Slot O, Ottaviani S, Richette P, MacMullan PA, Chapman PT, Lipsky PE, Robinson P, Khanna PP, Gancheva RN, Grainger R, Johnson RJ, Te Kampe R, Keenan RT, Tedeschi SK, Kim S, Choi SJ, Fields TR, Bardin T, Uhlig T, Jansen T, Merriman T, Pascart T, Neogi T, Klück V, Louthrenoo W, Dalbeth N. PMID: 31501138.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    6. Effect of Dietary and Supplemental Omega-3 Polyunsaturated Fatty Acids on Risk of Recurrent Gout Flares. Arthritis Rheumatol. 2019 09; 71(9):1580-1586. Zhang M, Zhang Y, Terkeltaub R, Chen C, Neogi T. PMID: 30908893.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    7. Risk of gout flares after vaccination: a prospective case cross-over study. Ann Rheum Dis. 2019 11; 78(11):1601-1604. Yokose C, McCormick N, Chen C, Neogi T, Chaisson C, Terkeltaub R, Hunter DJ, Zhang Y, Choi H. PMID: 31366470.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    8. Thiazide diuretics and risk of knee replacement surgery among patients with knee osteoarthritis: a general population-based cohort study. Osteoarthritis Cartilage. 2019 10; 27(10):1454-1461. Wei J, Neogi T, Terkeltaub R, Fenves AZ, Zeng C, Misra D, Choi HK, Lei G, Zhang Y. PMID: 31181261.
      View in: PubMed   Mentions:    Fields:    
    9. Choline Uptake and Metabolism Modulate Macrophage IL-1ß and IL-18 Production. Cell Metab. 2019 06 04; 29(6):1350-1362.e7. Sanchez-Lopez E, Zhong Z, Stubelius A, Sweeney SR, Booshehri LM, Antonucci L, Liu-Bryan R, Lodi A, Terkeltaub R, Lacal JC, Murphy AN, Hoffman HM, Tiziani S, Guma M, Karin M. PMID: 30982734.
      View in: PubMed   Mentions: 13     Fields:    
    10. A vascular smooth muscle cell X-box binding protein 1 and transglutaminase 2 regulatory circuit limits neointimal hyperplasia. PLoS One. 2019; 14(4):e0212235. Serrano RL, Yu W, Graham RM, Bryan RL, Terkeltaub R. PMID: 30943188.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    11. Gout, Hyperuricemia, and Crystal-Associated Disease Network Consensus Statement Regarding Labels and Definitions for Disease Elements in Gout. Arthritis Care Res (Hoboken). 2019 03; 71(3):427-434. Bursill D, Taylor WJ, Terkeltaub R, Kuwabara M, Merriman TR, Grainger R, Pineda C, Louthrenoo W, Edwards NL, Andrés M, Vargas-Santos AB, Roddy E, Pascart T, Lin CT, Perez-Ruiz F, Tedeschi SK, Kim SC, Harrold LR, McCarthy G, Kumar N, Chapman PT, Tausche AK, Vazquez-Mellado J, Gutierrez M, da Rocha Castelar-Pinheiro G, Richette P, Pascual E, Fisher MC, Burgos-Vargas R, Robinson PC, Singh JA, Jansen TL, Saag KG, Slot O, Uhlig T, Solomon DH, Keenan RT, Scire CA, Biernat-Kaluza E, Dehlin M, Nuki G, Schlesinger N, Janssen M, Stamp LK, Sivera F, Reginato AM, Jacobsson L, Lioté F, Ea HK, Rosenthal A, Bardin T, Choi HK, Hershfield MS, Czegley C, Choi SJ, Dalbeth N. PMID: 29799677.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    12. Reply. Arthritis Rheumatol. 2019 03; 71(3):481-482. Choi H, Neogi T, Stamp L, Dalbeth N, Terkeltaub R. PMID: 30295436.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    13. Efficacy and safety during extended treatment of lesinurad in combination with febuxostat in patients with tophaceous gout: CRYSTAL extension study. Arthritis Res Ther. 2019 01 07; 21(1):8. Dalbeth N, Jones G, Terkeltaub R, Khanna D, Fung M, Baumgartner S, Perez-Ruiz F. PMID: 30616614.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    14. Integrated safety studies of the urate reabsorption inhibitor lesinurad in treatment of gout. Rheumatology (Oxford). 2019 01 01; 58(1):61-69. Terkeltaub R, Saag KG, Goldfarb DS, Baumgartner S, Schechter BM, Valiyil R, Jalal D, Pillinger M, White WB. PMID: 30124941.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. New Perspectives in Rheumatology: Implications of the Cardiovascular Safety of Febuxostat and Allopurinol in Patients With Gout and Cardiovascular Morbidities Trial and the Associated Food and Drug Administration Public Safety Alert. Arthritis Rheumatol. 2018 11; 70(11):1702-1709. Choi H, Neogi T, Stamp L, Dalbeth N, Terkeltaub R. PMID: 29869840.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    16. Enpp1 inhibits ectopic joint calcification and maintains articular chondrocytes by repressing hedgehog signaling. Development. 2018 09 20; 145(18). Jin Y, Cong Q, Gvozdenovic-Jeremic J, Hu J, Zhang Y, Terkeltaub R, Yang Y. PMID: 30111653.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    17. Arhalofenate acid inhibits monosodium urate crystal-induced inflammatory responses through activation of AMP-activated protein kinase (AMPK) signaling. Arthritis Res Ther. 2018 09 06; 20(1):204. McWherter C, Choi YJ, Serrano RL, Mahata SK, Terkeltaub R, Liu-Bryan R. PMID: 30189890.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    18. Activation of AMPK-SIRT3 signaling is chondroprotective by preserving mitochondrial DNA integrity and function. Osteoarthritis Cartilage. 2018 11; 26(11):1539-1550. Chen LY, Wang Y, Terkeltaub R, Liu-Bryan R. PMID: 30031925.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    19. Modulation of matrix metabolism by ATP-citrate lyase in articular chondrocytes. J Biol Chem. 2018 08 03; 293(31):12259-12270. Chen LY, Lotz M, Terkeltaub R, Liu-Bryan R. PMID: 29929979.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    20. Review: Unmet Needs and the Path Forward in Joint Disease Associated With Calcium Pyrophosphate Crystal Deposition. Arthritis Rheumatol. 2018 08; 70(8):1182-1191. Abhishek A, Neogi T, Choi H, Doherty M, Rosenthal AK, Terkeltaub R. PMID: 29609209.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    21. Impaired Proteasomal Function in Human Osteoarthritic Chondrocytes Can Contribute to Decreased Levels of SOX9 and Aggrecan. Arthritis Rheumatol. 2018 07; 70(7):1030-1041. Serrano RL, Chen LY, Lotz MK, Liu-Bryan R, Terkeltaub R. PMID: 29457374.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    22. Prospective associations of C-reactive protein (CRP) levels and CRP genetic risk scores with risk of total knee and hip replacement for osteoarthritis in a diverse cohort. Osteoarthritis Cartilage. 2018 08; 26(8):1038-1044. Shadyab AH, Terkeltaub R, Kooperberg C, Reiner A, Eaton CB, Jackson RD, Krok-Schoen JL, Salem RM, LaCroix AZ. PMID: 29758352.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    23. The nomenclature of the basic disease elements of gout: A content analysis of contemporary medical journals. Semin Arthritis Rheum. 2018 12; 48(3):456-461. Bursill D, Taylor WJ, Terkeltaub R, Dalbeth N. PMID: 29706241.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    24. Dose-response relationship between lower serum magnesium level and higher prevalence of knee chondrocalcinosis. Arthritis Res Ther. 2017 Oct 24; 19(1):236. Zeng C, Wei J, Terkeltaub R, Yang T, Choi HK, Wang YL, Xie DX, Hunter DJ, Zhang Y, Li H, Cui Y, Li LJ, Lei GH. PMID: 29065924.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    25. What makes gouty inflammation so variable? BMC Med. 2017 08 18; 15(1):158. Terkeltaub R. PMID: 28818081.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    26. Discordant American College of Physicians and international rheumatology guidelines for gout management: consensus statement of the Gout, Hyperuricemia and Crystal-Associated Disease Network (G-CAN). Nat Rev Rheumatol. 2017 Sep; 13(9):561-568. Dalbeth N, Bardin T, Doherty M, Lioté F, Richette P, Saag KG, So AK, Stamp LK, Choi HK, Terkeltaub R. PMID: 28794514.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    27. Lesinurad, a Selective Uric Acid Reabsorption Inhibitor, in Combination With Febuxostat in Patients With Tophaceous Gout: Findings of a Phase III Clinical Trial. Arthritis Rheumatol. 2017 09; 69(9):1903-1913. Dalbeth N, Jones G, Terkeltaub R, Khanna D, Kopicko J, Bhakta N, Adler S, Fung M, Storgard C, Baumgartner S, Perez-Ruiz F. PMID: 28597604.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCTClinical Trials
    28. Sex differences in gout characteristics: tailoring care for women and men. BMC Musculoskelet Disord. 2017 03 14; 18(1):108. Harrold LR, Etzel CJ, Gibofsky A, Kremer JM, Pillinger MH, Saag KG, Schlesinger N, Terkeltaub R, Cox V, Greenberg JD. PMID: 28292303.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    29. PPARGC1B: insight into the expression of the gouty inflammation phenotype: PPARGC1B and gouty inflammation. Rheumatology (Oxford). 2017 03 01; 56(3):323-325. Merriman T, Terkeltaub R. PMID: 28003496.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    30. Review: Gout: A Roadmap to Approaches for Improving Global Outcomes. Arthritis Rheumatol. 2017 01; 69(1):22-34. Dalbeth N, Choi HK, Terkeltaub R. PMID: 27389665.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    31. Emerging uricosurics for gout. Expert Rev Clin Pharmacol. 2017 03; 10(3):247-249. Terkeltaub R. PMID: 27937050.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    32. Systematic review and quality analysis of emerging diagnostic measures for calcium pyrophosphate crystal deposition disease. RMD Open. 2016; 2(2):e000339. Wu Y, Chen K, Terkeltaub R. PMID: 27933211.
      View in: PubMed   Mentions:
    33. Erratum to: Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney. Arthritis Res Ther. 2016 10 12; 18(1):236. Miner JN, Tan PK, Hyndman D, Liu S, Iverson C, Nanavati P, Hagerty DT, Manhard K, Shen Z, Girardet JL, Yeh LT, Terkeltaub R, Quart B. PMID: 27733209.
      View in: PubMed   Mentions:    Fields:    
    34. Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney. Arthritis Res Ther. 2016 10 03; 18(1):214. Miner JN, Tan PK, Hyndman D, Liu S, Iverson C, Nanavati P, Hagerty DT, Manhard K, Shen Z, Girardet JL, Yeh LT, Terkeltaub R, Quart B. PMID: 27716403.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCellsCTClinical Trials
    35. Development of Preliminary Remission Criteria for Gout Using Delphi and 1000Minds Consensus Exercises. Arthritis Care Res (Hoboken). 2016 05; 68(5):667-72. de Lautour H, Taylor WJ, Adebajo A, Alten R, Burgos-Vargas R, Chapman P, Cimmino MA, da Rocha Castelar Pinheiro G, Day R, Harrold LR, Helliwell P, Janssen M, Kerr G, Kavanaugh A, Khanna D, Khanna PP, Lin C, Louthrenoo W, McCarthy G, Vazquez-Mellado J, Mikuls TR, Neogi T, Ogdie A, Perez-Ruiz F, Schlesinger N, Ralph Schumacher H, Scirè CA, Singh JA, Sivera F, Slot O, Stamp LK, Tausche AK, Terkeltaub R, Uhlig T, van de Laar M, White D, Yamanaka H, Zeng X, Dalbeth N. PMID: 26414176.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    36. Racial disparities in the risk of Stevens-Johnson Syndrome and toxic epidermal necrolysis as urate-lowering drug adverse events in the United States. Semin Arthritis Rheum. 2016 10; 46(2):253-258. Lu N, Rai SK, Terkeltaub R, Kim SC, Menendez ME, Choi HK. PMID: 27217070.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    37. Editorial: Can GPR43 Sensing of Short-Chain Fatty Acids Unchain Inflammasome-Driven Arthritis? Arthritis Rheumatol. 2015 Jun; 67(6):1419-23. Haslberger A, Terkeltaub R. PMID: 25914362.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    38. Mitochondrial biogenesis is impaired in osteoarthritis chondrocytes but reversible via peroxisome proliferator-activated receptor ? coactivator 1a. Arthritis Rheumatol. 2015 May; 67(8):2141-53. Wang Y, Zhao X, Lotz M, Terkeltaub R, Liu-Bryan R. PMID: 25940958.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    39. Peroxisome proliferator-activated receptor ? coactivator 1a and FoxO3A mediate chondroprotection by AMP-activated protein kinase. Arthritis Rheumatol. 2014 Nov; 66(11):3073-82. Zhao X, Petursson F, Viollet B, Lotz M, Terkeltaub R, Liu-Bryan R. PMID: 25047750.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    40. AMP-activated protein kinase suppresses urate crystal-induced inflammation and transduces colchicine effects in macrophages. Ann Rheum Dis. 2016 Jan; 75(1):286-94. Wang Y, Viollet B, Terkeltaub R, Liu-Bryan R. PMID: 25362043.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    41. Emerging regulators of the inflammatory process in osteoarthritis. Nat Rev Rheumatol. 2015 Jan; 11(1):35-44. Liu-Bryan R, Terkeltaub R. PMID: 25266449.
      View in: PubMed   Mentions: 91     Fields:    Translation:HumansAnimalsCells
    42. Apolipoprotein a-I at the interface of vascular inflammation and arthritis. Arterioscler Thromb Vasc Biol. 2014 Mar; 34(3):474-6. Terkeltaub R. PMID: 24554604.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    43. Treatment of acute gout: a systematic review. Semin Arthritis Rheum. 2014 Aug; 44(1):31-8. Khanna PP, Gladue HS, Singh MK, FitzGerald JD, Bae S, Prakash S, Kaldas M, Gogia M, Berrocal V, Townsend W, Terkeltaub R, Khanna D. PMID: 24650777.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    44. Mono-allelic and bi-allelic ENPP1 deficiency promote post-injury neointimal hyperplasia associated with increased C/EBP homologous protein expression. Atherosclerosis. 2014 Apr; 233(2):493-502. Serrano RL, Yu W, Terkeltaub R. PMID: 24530784.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    45. Gout: multinational gout guidelines: how do we move beyond 'déjà vu'? Nat Rev Rheumatol. 2013 Oct; 9(10):567-9. Terkeltaub R. PMID: 24045709.
      View in: PubMed   Mentions:    Fields:    
    46. Linked decreases in liver kinase B1 and AMP-activated protein kinase activity modulate matrix catabolic responses to biomechanical injury in chondrocytes. Arthritis Res Ther. 2013 Jul 25; 15(4):R77. Petursson F, Husa M, June R, Lotz M, Terkeltaub R, Liu-Bryan R. PMID: 23883619.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    47. Are cherries now ripe for use as a complementary therapeutic in gout? Appraisal of the state of evidence. Evid Based Med. 2013 Dec; 18(6):230-1. Terkeltaub R. PMID: 23416419.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    48. A delphi exercise to identify characteristic features of gout - opinions from patients and physicians, the first stage in developing new classification criteria. J Rheumatol. 2013 Apr; 40(4):498-505. Prowse RL, Dalbeth N, Kavanaugh A, Adebajo AO, Gaffo AL, Terkeltaub R, Mandell BF, Suryana BP, Goldenstein-Schainberg C, Diaz-Torne C, Khanna D, Lioté F, Mccarthy G, Kerr GS, Yamanaka H, Janssens H, Baraf HF, Chen JH, Vazquez-Mellado J, Harrold LR, Stamp LK, Van De Laar MA, Janssen M, Doherty M, Boers M, Edwards NL, Gow P, Chapman P, Khanna P, Helliwell PS, Grainger R, Schumacher HR, Neogi T, Jansen TL, Louthrenoo W, Sivera F, Taylor WJ, Alten R. PMID: 23418379.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    49. Rilonacept in the treatment of acute gouty arthritis: a randomized, controlled clinical trial using indomethacin as the active comparator. Arthritis Res Ther. 2013 Feb 01; 15(1):R25. Terkeltaub RA, Schumacher HR, Carter JD, Baraf HS, Evans RR, Wang J, King-Davis S, Weinstein SP. PMID: 23375025.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCTClinical Trials
    50. C/EBP homologous protein drives pro-catabolic responses in chondrocytes. Arthritis Res Ther. 2013; 15(6):R218. Husa M, Petursson F, Lotz M, Terkeltaub R, Liu-Bryan R. PMID: 24351550.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    51. Imaging joints for calcium pyrophosphate crystal deposition: a knock to the knees. Arthritis Res Ther. 2012 Dec 27; 14(6):128. Terkeltaub R. PMID: 23270654.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    52. Rilonacept (interleukin-1 trap) for prevention of gout flares during initiation of uric acid-lowering therapy: results from a phase III randomized, double-blind, placebo-controlled, confirmatory efficacy study. Arthritis Care Res (Hoboken). 2012 Oct; 64(10):1462-70. Schumacher HR, Evans RR, Saag KG, Clower J, Jennings W, Weinstein SP, Yancopoulos GD, Wang J, Terkeltaub R. PMID: 22549879.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCTClinical Trials
    53. 2012 American College of Rheumatology guidelines for management of gout. Part 2: therapy and antiinflammatory prophylaxis of acute gouty arthritis. Arthritis Care Res (Hoboken). 2012 Oct; 64(10):1447-61. Khanna D, Khanna PP, Fitzgerald JD, Singh MK, Bae S, Neogi T, Pillinger MH, Merill J, Lee S, Prakash S, Kaldas M, Gogia M, Perez-Ruiz F, Taylor W, Lioté F, Choi H, Singh JA, Dalbeth N, Kaplan S, Niyyar V, Jones D, Yarows SA, Roessler B, Kerr G, King C, Levy G, Furst DE, Edwards NL, Mandell B, Schumacher HR, Robbins M, Wenger N, Terkeltaub R. PMID: 23024029.
      View in: PubMed   Mentions: 119     Fields:    Translation:Humans
    54. 2012 American College of Rheumatology guidelines for management of gout. Part 1: systematic nonpharmacologic and pharmacologic therapeutic approaches to hyperuricemia. Arthritis Care Res (Hoboken). 2012 Oct; 64(10):1431-46. Khanna D, Fitzgerald JD, Khanna PP, Bae S, Singh MK, Neogi T, Pillinger MH, Merill J, Lee S, Prakash S, Kaldas M, Gogia M, Perez-Ruiz F, Taylor W, Lioté F, Choi H, Singh JA, Dalbeth N, Kaplan S, Niyyar V, Jones D, Yarows SA, Roessler B, Kerr G, King C, Levy G, Furst DE, Edwards NL, Mandell B, Schumacher HR, Robbins M, Wenger N, Terkeltaub R. PMID: 23024028.
      View in: PubMed   Mentions: 300     Fields:    Translation:Humans
    55. The growing array of innate inflammatory ignition switches in osteoarthritis. Arthritis Rheum. 2012 Jul; 64(7):2055-8. Liu-Bryan R, Terkeltaub R. PMID: 22488656.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    56. Vanin-1 pantetheinase drives smooth muscle cell activation in post-arterial injury neointimal hyperplasia. PLoS One. 2012; 7(6):e39106. Dammanahalli KJ, Stevens S, Terkeltaub R. PMID: 22720042.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    57. Novel ANKH amino terminus mutation (Pro5Ser) associated with early-onset calcium pyrophosphate disease with associated phosphaturia. J Clin Rheumatol. 2012 Jun; 18(4):192-5. Gruber BL, Couto AR, Armas JB, Brown MA, Finzel K, Terkeltaub RA. PMID: 22647861.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    58. RAGE signaling mediates post-injury arterial neointima formation by suppression of liver kinase B1 and AMPK activity. Atherosclerosis. 2012 Jun; 222(2):417-25. Yu W, Liu-Bryan R, Stevens S, Damanahalli JK, Terkeltaub R. PMID: 22552116.
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    59. Rilonacept (interleukin-1 trap) in the prevention of acute gout flares during initiation of urate-lowering therapy: results of a phase II randomized, double-blind, placebo-controlled trial. Arthritis Rheum. 2012 Mar; 64(3):876-84. Schumacher HR, Sundy JS, Terkeltaub R, Knapp HR, Mellis SJ, Stahl N, Yancopoulos GD, Soo Y, King-Davis S, Weinstein SP, Radin AR. PMID: 22223180.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCTClinical Trials
    60. Are either or both hyperuricemia and xanthine oxidase directly toxic to the vasculature? A critical appraisal. Arthritis Rheum. 2012 Feb; 64(2):327-38. Neogi T, George J, Rekhraj S, Struthers AD, Choi H, Terkeltaub RA. PMID: 21953377.
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    61. Generalized arterial calcification of infancy and pseudoxanthoma elasticum can be caused by mutations in either ENPP1 or ABCC6. Am J Hum Genet. 2012 Jan 13; 90(1):25-39. Nitschke Y, Baujat G, Botschen U, Wittkampf T, du Moulin M, Stella J, Le Merrer M, Guest G, Lambot K, Tazarourte-Pinturier MF, Chassaing N, Roche O, Feenstra I, Loechner K, Deshpande C, Garber SJ, Chikarmane R, Steinmann B, Shahinyan T, Martorell L, Davies J, Smith WE, Kahler SG, McCulloch M, Wraige E, Loidi L, Höhne W, Martin L, Hadj-Rabia S, Terkeltaub R, Rutsch F. PMID: 22209248.
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    62. Npp1 promotes atherosclerosis in ApoE knockout mice. J Cell Mol Med. 2011 Nov; 15(11):2273-83. Nitschke Y, Weissen-Plenz G, Terkeltaub R, Rutsch F. PMID: 21477221.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    63. Genetics in arterial calcification: pieces of a puzzle and cogs in a wheel. Circ Res. 2011 Aug 19; 109(5):578-92. Rutsch F, Nitschke Y, Terkeltaub R. PMID: 21852556.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimals
    64. Novel evidence-based colchicine dose-reduction algorithm to predict and prevent colchicine toxicity in the presence of cytochrome P450 3A4/P-glycoprotein inhibitors. Arthritis Rheum. 2011 Aug; 63(8):2226-37. Terkeltaub RA, Furst DE, Digiacinto JL, Kook KA, Davis MW. PMID: 21480191.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCTClinical Trials
    65. Chondrocyte AMP-activated protein kinase activity suppresses matrix degradation responses to proinflammatory cytokines interleukin-1ß and tumor necrosis factor a. Arthritis Rheum. 2011 Jul; 63(7):1928-37. Terkeltaub R, Yang B, Lotz M, Liu-Bryan R. PMID: 21400477.
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    66. Minimally important differences of the gout impact scale in a randomized controlled trial. Rheumatology (Oxford). 2011 Jul; 50(7):1331-6. Khanna D, Sarkin AJ, Khanna PP, Shieh MM, Kavanaugh AF, Terkeltaub RA, Lee SJ, Singh JA, Hirsch JD. PMID: 21372003.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansPHPublic Health
    67. Arterial calcification is driven by RAGE in Enpp1-/- mice. J Vasc Res. 2011; 48(3):227-35. Cecil DL, Terkeltaub RA. PMID: 21099228.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    68. Serum urate is not associated with coronary artery calcification: the NHLBI Family Heart Study. J Rheumatol. 2011 Jan; 38(1):111-7. Neogi T, Terkeltaub R, Ellison RC, Hunt S, Zhang Y. PMID: 20889594.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    69. Health care utilization in patients with gout. Semin Arthritis Rheum. 2011 Jun; 40(6):501-11. Singh JA, Sarkin A, Shieh M, Khanna D, Terkeltaub R, Lee SJ, Kavanaugh A, Hirsch JD. PMID: 20828793.
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    70. Predictors of doctor-rated and patient-rated gout severity: gout impact scales improve assessment. J Eval Clin Pract. 2010 Dec; 16(6):1244-7. Sarkin AJ, Levack AE, Shieh MM, Kavanaugh AF, Khanna D, Singh JA, Terkeltaub RA, Lee SJ, Hirsch JD. PMID: 20722884.
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    71. Cartilage cell clusters. Arthritis Rheum. 2010 Aug; 62(8):2206-18. Lotz MK, Otsuki S, Grogan SP, Sah R, Terkeltaub R, D'Lima D. PMID: 20506158.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimals
    72. Chondrocyte innate immune myeloid differentiation factor 88-dependent signaling drives procatabolic effects of the endogenous Toll-like receptor 2/Toll-like receptor 4 ligands low molecular weight hyaluronan and high mobility group box chromosomal protein 1 in mice. Arthritis Rheum. 2010 Jul; 62(7):2004-12. Liu-Bryan R, Terkeltaub R. PMID: 20506365.
      View in: PubMed   Mentions: 54     Fields:    Translation:AnimalsCells
    73. Shifting HIFs in osteoarthritis. Nat Med. 2010 Jun; 16(6):641-4. Husa M, Liu-Bryan R, Terkeltaub R. PMID: 20526316.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    74. High versus low dosing of oral colchicine for early acute gout flare: Twenty-four-hour outcome of the first multicenter, randomized, double-blind, placebo-controlled, parallel-group, dose-comparison colchicine study. Arthritis Rheum. 2010 Apr; 62(4):1060-8. Terkeltaub RA, Furst DE, Bennett K, Kook KA, Crockett RS, Davis MW. PMID: 20131255.
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    75. Gout disease-specific quality of life and the association with gout characteristics. Patient Relat Outcome Meas. 2010 Mar 01; 2010:1-8. Hirsch JD, Terkeltaub R, Khanna D, Singh J, Sarkin A, Shieh M, Kavanaugh A, Lee SJ. PMID: 21686040.
      View in: PubMed   Mentions:
    76. Update on gout: new therapeutic strategies and options. Nat Rev Rheumatol. 2010 Jan; 6(1):30-8. Terkeltaub R. PMID: 20046204.
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    77. Inorganic pyrophosphatase induces type I collagen in osteoblasts. Bone. 2010 Jan; 46(1):81-90. Polewski MD, Johnson KA, Foster M, Millán JL, Terkeltaub R. PMID: 19733704.
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    78. The interleukin 1 inhibitor rilonacept in treatment of chronic gouty arthritis: results of a placebo-controlled, monosequence crossover, non-randomised, single-blind pilot study. Ann Rheum Dis. 2009 Oct; 68(10):1613-7. Terkeltaub R, Sundy JS, Schumacher HR, Murphy F, Bookbinder S, Biedermann S, Wu R, Mellis S, Radin A. PMID: 19635719.
      View in: PubMed   Mentions: 81     Fields:    Translation:Humans
    79. Gout. Novel therapies for treatment of gout and hyperuricemia. Arthritis Res Ther. 2009; 11(4):236. Terkeltaub R. PMID: 19664185.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    80. Gout Study Group: update on hyperuricemia and gout. Joint Bone Spine. 2009 Jul; 76(4):444-6. Terkeltaub R, Zelman D, Scavulli J, Perez-Ruiz F, Lioté F. PMID: 19559637.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    81. Hyperalgesia, synovitis and multiple biomarkers of inflammation are suppressed by interleukin 1 inhibition in a novel animal model of gouty arthritis. Ann Rheum Dis. 2009 Oct; 68(10):1602-8. Torres R, Macdonald L, Croll SD, Reinhardt J, Dore A, Stevens S, Hylton DM, Rudge JS, Liu-Bryan R, Terkeltaub RA, Yancopoulos GD, Murphy AJ. PMID: 19528034.
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    82. The pattern recognition receptor CD36 is a chondrocyte hypertrophy marker associated with suppression of catabolic responses and promotion of repair responses to inflammatory stimuli. J Immunol. 2009 Apr 15; 182(8):5024-31. Cecil DL, Appleton CT, Polewski MD, Mort JS, Schmidt AM, Bendele A, Beier F, Terkeltaub R. PMID: 19342682.
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    83. A sugar transporter regulates serum urate levels: implications for prevention and management of hyperuricemia in gout. Curr Rheumatol Rep. 2009 Apr; 11(2):83-6. Terkeltaub RA. PMID: 19296879.
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    84. A critical reappraisal of allopurinol dosing, safety, and efficacy for hyperuricemia in gout. Curr Rheumatol Rep. 2009 Apr; 11(2):135-40. Chao J, Terkeltaub R. PMID: 19296886.
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    85. Transglutaminase 2 is a marker of chondrocyte hypertrophy and osteoarthritis severity in the Hartley guinea pig model of knee OA. Osteoarthritis Cartilage. 2009 Aug; 17(8):1056-64. Huebner JL, Johnson KA, Kraus VB, Terkeltaub RA. PMID: 19328881.
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    86. Perceptions of disease and health-related quality of life among patients with gout. Rheumatology (Oxford). 2009 May; 48(5):582-6. Lee SJ, Hirsch JD, Terkeltaub R, Khanna D, Singh JA, Sarkin A, Kavanaugh A. PMID: 19307257.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    87. Serum uric acid is associated with carotid plaques: the National Heart, Lung, and Blood Institute Family Heart Study. J Rheumatol. 2009 Feb; 36(2):378-84. Neogi T, Ellison RC, Hunt S, Terkeltaub R, Felson DT, Zhang Y. PMID: 19012359.
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    88. Macrophage glucocorticoid receptors join the intercellular dialogue in atherosclerotic lesion calcification. Arterioscler Thromb Vasc Biol. 2008 Dec; 28(12):2096-8. Terkeltaub R. PMID: 19020314.
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    89. Hypophosphatemia, hyperphosphaturia, and bisphosphonate treatment are associated with survival beyond infancy in generalized arterial calcification of infancy. Circ Cardiovasc Genet. 2008 Dec; 1(2):133-40. Rutsch F, Böyer P, Nitschke Y, Ruf N, Lorenz-Depierieux B, Wittkampf T, Weissen-Plenz G, Fischer RJ, Mughal Z, Gregory JW, Davies JH, Loirat C, Strom TM, Schnabel D, Nürnberg P, Terkeltaub R. PMID: 20016754.
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    90. Colchicine update: 2008. Semin Arthritis Rheum. 2009 Jun; 38(6):411-9. Terkeltaub RA. PMID: 18973929.
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    91. Evaluation of an instrument assessing influence of Gout on health-related quality of life. J Rheumatol. 2008 Dec; 35(12):2406-14. Hirsch JD, Lee SJ, Terkeltaub R, Khanna D, Singh J, Sarkin A, Harvey J, Kavanaugh A. PMID: 18925685.
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    92. Transamidation by transglutaminase 2 transforms S100A11 calgranulin into a procatabolic cytokine for chondrocytes. J Immunol. 2008 Jun 15; 180(12):8378-85. Cecil DL, Terkeltaub R. PMID: 18523305.
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    93. Factor XIIIA mobilizes transglutaminase 2 to induce chondrocyte hypertrophic differentiation. J Cell Sci. 2008 Jul 01; 121(Pt 13):2256-64. Johnson KA, Rose DM, Terkeltaub RA. PMID: 18544639.
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    94. Enzyme replacement therapy for murine hypophosphatasia. J Bone Miner Res. 2008 Jun; 23(6):777-87. Millán JL, Narisawa S, Lemire I, Loisel TP, Boileau G, Leonard P, Gramatikova S, Terkeltaub R, Camacho NP, McKee MD, Crine P, Whyte MP. PMID: 18086009.
      View in: PubMed   Mentions: 83     Fields:    Translation:HumansAnimals
    95. Transglutaminase 2 is central to induction of the arterial calcification program by smooth muscle cells. Circ Res. 2008 Mar 14; 102(5):529-37. Johnson KA, Polewski M, Terkeltaub RA. PMID: 18202319.
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    96. Vanin-1 pantetheinase drives increased chondrogenic potential of mesenchymal precursors in ank/ank mice. Am J Pathol. 2008 Feb; 172(2):440-53. Johnson KA, Yao W, Lane NE, Naquet P, Terkeltaub RA. PMID: 18187567.
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    97. Learning how and when to employ uricase as bridge therapy in refractory gout. J Rheumatol. 2007 Oct; 34(10):1955-8. Terkeltaub R. PMID: 17924606.
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    98. Novel mouse model of autosomal semidominant adult hypophosphatasia has a splice site mutation in the tissue nonspecific alkaline phosphatase gene Akp2. J Bone Miner Res. 2007 Sep; 22(9):1397-407. Hough TA, Polewski M, Johnson K, Cheeseman M, Nolan PM, Vizor L, Rastan S, Boyde A, Pritzker K, Hunter AJ, Fisher EM, Terkeltaub R, Brown SD. PMID: 17539739.
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    99. Last call for alcohol in gout? Curr Rheumatol Rep. 2007 Jun; 9(3):229-30. Hennigan S, Terkeltaub R. PMID: 17531176.
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    100. Transglutaminase 2 regulates mallory body inclusion formation and injury-associated liver enlargement. Gastroenterology. 2007 Apr; 132(4):1515-26. Strnad P, Harada M, Siegel M, Terkeltaub RA, Graham RM, Khosla C, Omary MB. PMID: 17408647.
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    101. Calcification of human articular knee cartilage is primarily an effect of aging rather than osteoarthritis. Osteoarthritis Cartilage. 2007 May; 15(5):559-65. Mitsuyama H, Healey RM, Terkeltaub RA, Coutts RD, Amiel D. PMID: 17276093.
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    102. Engagement of CD14 mediates the inflammatory potential of monosodium urate crystals. J Immunol. 2006 Nov 01; 177(9):6370-8. Scott P, Ma H, Viriyakosol S, Terkeltaub R, Liu-Bryan R. PMID: 17056568.
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    103. Lower prevalence of chondrocalcinosis in Chinese subjects in Beijing than in white subjects in the United States: the Beijing Osteoarthritis Study. Arthritis Rheum. 2006 Nov; 54(11):3508-12. Zhang Y, Terkeltaub R, Nevitt M, Xu L, Neogi T, Aliabadi P, Niu J, Felson DT. PMID: 17075853.
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    104. Transglutaminase 2 limits murine peritoneal acute gout-like inflammation by regulating macrophage clearance of apoptotic neutrophils. Arthritis Rheum. 2006 Oct; 54(10):3363-71. Rose DM, Sydlaske AD, Agha-Babakhani A, Johnson K, Terkeltaub R. PMID: 17009310.
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    105. Elevated skeletal osteopontin levels contribute to the hypophosphatasia phenotype in Akp2(-/-) mice. J Bone Miner Res. 2006 Sep; 21(9):1377-86. Harmey D, Johnson KA, Zelken J, Camacho NP, Hoylaerts MF, Noda M, Terkeltaub R, Millán JL. PMID: 16939396.
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    106. Physiologic and pathologic functions of the NPP nucleotide pyrophosphatase/phosphodiesterase family focusing on NPP1 in calcification. Purinergic Signal. 2006 Jun; 2(2):371-7. Terkeltaub R. PMID: 18404477.
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    107. New developments in clinically relevant mechanisms and treatment of hyperuricemia. Curr Rheumatol Rep. 2006 Jun; 8(3):224-30. Lee SJ, Terkeltaub RA. PMID: 16901081.
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    108. Lack of association between chondrocalcinosis and increased risk of cartilage loss in knees with osteoarthritis: results of two prospective longitudinal magnetic resonance imaging studies. Arthritis Rheum. 2006 Jun; 54(6):1822-8. Neogi T, Nevitt M, Niu J, LaValley MP, Hunter DJ, Terkeltaub R, Carbone L, Chen H, Harris T, Kwoh K, Guermazi A, Felson DT. PMID: 16729275.
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    109. Recent developments in our understanding of the renal basis of hyperuricemia and the development of novel antihyperuricemic therapeutics. Arthritis Res Ther. 2006; 8 Suppl 1:S4. Terkeltaub R, Bushinsky DA, Becker MA. PMID: 16820043.
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    110. The inflammatory process of gout and its treatment. Arthritis Res Ther. 2006; 8 Suppl 1:S3. Cronstein BN, Terkeltaub R. PMID: 16820042.
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    111. Up-regulated expression of the CXCR2 ligand KC/GRO-alpha in atherosclerotic lesions plays a central role in macrophage accumulation and lesion progression. Am J Pathol. 2006 Apr; 168(4):1385-95. Boisvert WA, Rose DM, Johnson KA, Fuentes ME, Lira SA, Curtiss LK, Terkeltaub RA. PMID: 16565511.
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    112. Low vitamin K status is associated with osteoarthritis in the hand and knee. Arthritis Rheum. 2006 Apr; 54(4):1255-61. Neogi T, Booth SL, Zhang YQ, Jacques PF, Terkeltaub R, Aliabadi P, Felson DT. PMID: 16572460.
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    113. Recent developments in diet and gout. Curr Opin Rheumatol. 2006 Mar; 18(2):193-8. Lee SJ, Terkeltaub RA, Kavanaugh A. PMID: 16462528.
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    114. Evil humors take their toll as innate immunity makes gouty joints TREM-ble. Arthritis Rheum. 2006 Feb; 54(2):383-6. Liu-Bryan R, Terkeltaub R. PMID: 16447213.
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    115. Hyperuricemia treatment: is creatinine clearance a safer allopurinol dosing meter than plasma creatinine levels? Nat Clin Pract Rheumatol. 2006 Feb; 2(2):68-9. Terkeltaub R. PMID: 16932657.
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    116. Leukocyte transglutaminase 2 expression limits atherosclerotic lesion size. Arterioscler Thromb Vasc Biol. 2006 Mar; 26(3):563-9. Boisvert WA, Rose DM, Boullier A, Quehenberger O, Sydlaske A, Johnson KA, Curtiss LK, Terkeltaub R. PMID: 16410462.
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    117. Gout in 2006: the perfect storm. Bull NYU Hosp Jt Dis. 2006; 64(1-2):82-6. Terkeltaub R. PMID: 17121496.
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    118. Inflammation-induced chondrocyte hypertrophy is driven by receptor for advanced glycation end products. J Immunol. 2005 Dec 15; 175(12):8296-302. Cecil DL, Johnson K, Rediske J, Lotz M, Schmidt AM, Terkeltaub R. PMID: 16339570.
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    119. Innate immunity conferred by Toll-like receptors 2 and 4 and myeloid differentiation factor 88 expression is pivotal to monosodium urate monohydrate crystal-induced inflammation. Arthritis Rheum. 2005 Sep; 52(9):2936-46. Liu-Bryan R, Scott P, Sydlaske A, Rose DM, Terkeltaub R. PMID: 16142712.
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    120. Sustained osteomalacia of long bones despite major improvement in other hypophosphatasia-related mineral deficits in tissue nonspecific alkaline phosphatase/nucleotide pyrophosphatase phosphodiesterase 1 double-deficient mice. Am J Pathol. 2005 Jun; 166(6):1711-20. Anderson HC, Harmey D, Camacho NP, Garimella R, Sipe JB, Tague S, Bi X, Johnson K, Terkeltaub R, Millán JL. PMID: 15920156.
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    121. What do epidemiologic studies tell us about hyperuricemia and cardiovascular disease and death? Curr Rheumatol Rep. 2005 Jun; 7(3):211-2. Wu CW, Terkeltaub R. PMID: 15918997.
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    122. Calcium-containing crystals and osteoarthritis: implications for the clinician. Curr Rheumatol Rep. 2005 Jun; 7(3):213-9. Wu CW, Terkeltaub R, Kalunian KC. PMID: 15918998.
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    123. Chondrocyte calcium-sensing receptor expression is up-regulated in early guinea pig knee osteoarthritis and modulates PTHrP, MMP-13, and TIMP-3 expression. Osteoarthritis Cartilage. 2005 May; 13(5):395-404. Burton DW, Foster M, Johnson KA, Hiramoto M, Deftos LJ, Terkeltaub R. PMID: 15882563.
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    124. TLR2 signaling in chondrocytes drives calcium pyrophosphate dihydrate and monosodium urate crystal-induced nitric oxide generation. J Immunol. 2005 Apr 15; 174(8):5016-23. Liu-Bryan R, Pritzker K, Firestein GS, Terkeltaub R. PMID: 15814732.
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    125. Association of sporadic chondrocalcinosis with a -4-basepair G-to-A transition in the 5'-untranslated region of ANKH that promotes enhanced expression of ANKH protein and excess generation of extracellular inorganic pyrophosphate. Arthritis Rheum. 2005 Apr; 52(4):1110-7. Zhang Y, Johnson K, Russell RG, Wordsworth BP, Carr AJ, Terkeltaub RA, Brown MA. PMID: 15818664.
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    126. Deficiencies of physiologic calcification inhibitors and low-grade inflammation in arterial calcification: lessons for cartilage calcification. Joint Bone Spine. 2005 Mar; 72(2):110-8. Rutsch F, Terkeltaub R. PMID: 15797489.
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    127. External GTP-bound transglutaminase 2 is a molecular switch for chondrocyte hypertrophic differentiation and calcification. J Biol Chem. 2005 Apr 15; 280(15):15004-12. Johnson KA, Terkeltaub RA. PMID: 15691824.
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    128. Increased hepatic levels of the insulin receptor inhibitor, PC-1/NPP1, induce insulin resistance and glucose intolerance. Diabetes. 2005 Feb; 54(2):367-72. Dong H, Maddux BA, Altomonte J, Meseck M, Accili D, Terkeltaub R, Johnson K, Youngren JF, Goldfine ID. PMID: 15677494.
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    129. The mutational spectrum of ENPP1 as arising after the analysis of 23 unrelated patients with generalized arterial calcification of infancy (GACI). Hum Mutat. 2005 Jan; 25(1):98. Ruf N, Uhlenberg B, Terkeltaub R, Nürnberg P, Rutsch F. PMID: 15605415.
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    130. Inorganic pyrophosphate (PPI) in pathologic calcification of articular cartilage. Front Biosci. 2005 Jan 01; 10:988-97. Johnson K, Terkeltaub R. PMID: 15569637.
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    131. Role of interleukin-8 in PiT-1 expression and CXCR1-mediated inorganic phosphate uptake in chondrocytes. Arthritis Rheum. 2005 Jan; 52(1):144-54. Cecil DL, Rose DM, Terkeltaub R, Liu-Bryan R. PMID: 15641067.
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    132. Chondrogenesis mediated by PPi depletion promotes spontaneous aortic calcification in NPP1-/- mice. Arterioscler Thromb Vasc Biol. 2005 Apr; 25(4):686-91. Johnson K, Polewski M, van Etten D, Terkeltaub R. PMID: 15625282.
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    133. Central role of complement membrane attack complex in monosodium urate crystal-induced neutrophilic rabbit knee synovitis. Arthritis Rheum. 2004 Aug; 50(8):2633-9. Tramontini N, Huber C, Liu-Bryan R, Terkeltaub RA, Kilgore KS. PMID: 15334478.
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    134. Gout: on the brink of novel therapeutic options for an ancient disease. Arthritis Rheum. 2004 Aug; 50(8):2400-14. Bieber JD, Terkeltaub RA. PMID: 15334451.
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    135. The role of hypertension in cyclosporine-induced hyperuricemia. Curr Rheumatol Rep. 2004 Jun; 6(3):215-6. Bieber J, Terkeltaub R. PMID: 15134600.
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    136. Calcification in calcium pyrophosphate dihydrate (CPPD) crystalline deposits in the knee: anatomic, radiographic, MR imaging, and histologic study in cadavers. Skeletal Radiol. 2004 Jul; 33(7):392-8. Abreu M, Johnson K, Chung CB, De Lima JE, Trudell D, Terkeltaub R, Pe S, Resnick D. PMID: 15138720.
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    137. Upregulated ank expression in osteoarthritis can promote both chondrocyte MMP-13 expression and calcification via chondrocyte extracellular PPi excess. Osteoarthritis Cartilage. 2004 Apr; 12(4):321-35. Johnson K, Terkeltaub R. PMID: 15023384.
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    138. Mediation of spontaneous knee osteoarthritis by progressive chondrocyte ATP depletion in Hartley guinea pigs. Arthritis Rheum. 2004 Apr; 50(4):1216-25. Johnson K, Svensson CI, Etten DV, Ghosh SS, Murphy AN, Powell HC, Terkeltaub R. PMID: 15077304.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    139. Concerted regulation of inorganic pyrophosphate and osteopontin by akp2, enpp1, and ank: an integrated model of the pathogenesis of mineralization disorders. Am J Pathol. 2004 Apr; 164(4):1199-209. Harmey D, Hessle L, Narisawa S, Johnson KA, Terkeltaub R, Millán JL. PMID: 15039209.
      View in: PubMed   Mentions: 150     Fields:    Translation:AnimalsCells
    140. Proline-rich tyrosine kinase 2 and Src kinase signaling transduce monosodium urate crystal-induced nitric oxide production and matrix metalloproteinase 3 expression in chondrocytes. Arthritis Rheum. 2004 Jan; 50(1):247-58. Liu R, Lioté F, Rose DM, Merz D, Terkeltaub R. PMID: 14730623.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    141. Subcellular targeting and function of osteoblast nucleotide pyrophosphatase phosphodiesterase 1. Am J Physiol Cell Physiol. 2004 May; 286(5):C1177-87. Vaingankar SM, Fitzpatrick TA, Johnson K, Goding JW, Maurice M, Terkeltaub R. PMID: 15075217.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    142. IL-8-mediated cell migration in endothelial cells depends on cathepsin B activity and transactivation of the epidermal growth factor receptor. J Immunol. 2003 Dec 15; 171(12):6714-22. Schraufstatter IU, Trieu K, Zhao M, Rose DM, Terkeltaub RA, Burger M. PMID: 14662875.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    143. Questions & answers. What's the difference between gout and pseudogout? Health News. 2003 Dec; 9(12):16. Terkeltaub RA. PMID: 14679973.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    144. Clinical practice. Gout. N Engl J Med. 2003 Oct 23; 349(17):1647-55. Terkeltaub RA. PMID: 14573737.
      View in: PubMed   Mentions: 101     Fields:    Translation:Humans
    145. IL-8/CXCL8 and growth-related oncogene alpha/CXCL1 induce chondrocyte hypertrophic differentiation. J Immunol. 2003 Oct 15; 171(8):4406-15. Merz D, Liu R, Johnson K, Terkeltaub R. PMID: 14530367.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansAnimalsCells
    146. Mutations in ENPP1 are associated with 'idiopathic' infantile arterial calcification. Nat Genet. 2003 Aug; 34(4):379-81. Rutsch F, Ruf N, Vaingankar S, Toliat MR, Suk A, Höhne W, Schauer G, Lehmann M, Roscioli T, Schnabel D, Epplen JT, Knisely A, Superti-Furga A, McGill J, Filippone M, Sinaiko AR, Vallance H, Hinrichs B, Smith W, Ferre M, Terkeltaub R, Nürnberg P. PMID: 12881724.
      View in: PubMed   Mentions: 158     Fields:    Translation:Humans
    147. Linked deficiencies in extracellular PP(i) and osteopontin mediate pathologic calcification associated with defective PC-1 and ANK expression. J Bone Miner Res. 2003 Jun; 18(6):994-1004. Johnson K, Goding J, Van Etten D, Sali A, Hu SI, Farley D, Krug H, Hessle L, Millán JL, Terkeltaub R. PMID: 12817751.
      View in: PubMed   Mentions: 73     Fields:    Translation:AnimalsCells
    148. Calcium pyrophosphate dihydrate and hydroxyapatite crystal deposition in the joint: new developments relevant to the clinician. Curr Rheumatol Rep. 2003 Jun; 5(3):235-43. Pay S, Terkeltaub R. PMID: 12744817.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    149. One of two chondrocyte-expressed isoforms of cartilage intermediate-layer protein functions as an insulin-like growth factor 1 antagonist. Arthritis Rheum. 2003 May; 48(5):1302-14. Johnson K, Farley D, Hu SI, Terkeltaub R. PMID: 12746903.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    150. Parallels between arterial and cartilage calcification: what understanding artery calcification can teach us about chondrocalcinosis. Curr Opin Rheumatol. 2003 May; 15(3):302-10. Rutsch F, Terkeltaub R. PMID: 12707585.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    151. Distinct transglutaminase 2-independent and transglutaminase 2-dependent pathways mediate articular chondrocyte hypertrophy. J Biol Chem. 2003 May 23; 278(21):18824-32. Johnson KA, van Etten D, Nanda N, Graham RM, Terkeltaub RA. PMID: 12606540.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    152. Parathyroid hormone-related peptide is a naturally occurring, protein kinase A-dependent angiogenesis inhibitor. Nat Med. 2002 Sep; 8(9):995-1003. Bakre MM, Zhu Y, Yin H, Burton DW, Terkeltaub R, Deftos LJ, Varner JA. PMID: 12185361.
      View in: PubMed   Mentions: 30     Fields:    Translation:Animals
    153. Tissue-nonspecific alkaline phosphatase and plasma cell membrane glycoprotein-1 are central antagonistic regulators of bone mineralization. Proc Natl Acad Sci U S A. 2002 Jul 09; 99(14):9445-9. Hessle L, Johnson KA, Anderson HC, Narisawa S, Sali A, Goding JW, Terkeltaub R, Millan JL. PMID: 12082181.
      View in: PubMed   Mentions: 204     Fields:    Translation:AnimalsCells
    154. Pseudogout, hypomagnesemia, and liver transplantation. Curr Rheumatol Rep. 2002 Jun; 4(3):243-4. Terkeltaub R. PMID: 12010609.
      View in: PubMed   Mentions:    Fields:    
    155. What does cartilage calcification tell us about osteoarthritis? J Rheumatol. 2002 Mar; 29(3):411-5. Terkeltaub RA. PMID: 11908551.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    156. Invited review: the mitochondrion in osteoarthritis. Mitochondrion. 2002 Feb; 1(4):301-19. Terkeltaub R, Johnson K, Murphy A, Ghosh S. PMID: 16120285.
      View in: PubMed   Mentions: 23     Fields:    
    157. Src family protein tyrosine kinase signaling mediates monosodium urate crystal-induced IL-8 expression by monocytic THP-1 cells. J Leukoc Biol. 2001 Dec; 70(6):961-8. Liu R, Aupperle K, Terkeltaub R. PMID: 11739559.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    158. The nucleoside triphosphate pyrophosphohydrolase isozyme PC-1 directly promotes cartilage calcification through chondrocyte apoptosis and increased calcium precipitation by mineralizing vesicles. J Rheumatol. 2001 Dec; 28(12):2681-91. Johnson K, Pritzker K, Goding J, Terkeltaub R. PMID: 11764218.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    159. Interleukin-1 induces pro-mineralizing activity of cartilage tissue transglutaminase and factor XIIIa. Am J Pathol. 2001 Jul; 159(1):149-63. Johnson K, Hashimoto S, Lotz M, Pritzker K, Terkeltaub R. PMID: 11438463.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    160. Comparative tissue distribution of the processing enzymes "prohormone thiol protease," and prohormone convertases 1 and 2, in human PTHrP-producing cell lines and mammalian neuroendocrine tissues. Endocrine. 2001 Jul; 15(2):217-24. Deftos LJ, Burton D, Hastings RH, Terkeltaub R, Hook VY. PMID: 11720250.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    161. Inorganic pyrophosphate generation and disposition in pathophysiology. Am J Physiol Cell Physiol. 2001 Jul; 281(1):C1-C11. Terkeltaub RA. PMID: 11401820.
      View in: PubMed   Mentions: 109     Fields:    Translation:HumansAnimalsCells
    162. Up-regulated expression of the phosphodiesterase nucleotide pyrophosphatase family member PC-1 is a marker and pathogenic factor for knee meniscal cartilage matrix calcification. Arthritis Rheum. 2001 May; 44(5):1071-81. Johnson K, Hashimoto S, Lotz M, Pritzker K, Goding J, Terkeltaub R. PMID: 11352238.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    163. High-efficiency non-viral transfection of primary chondrocytes and perichondrial cells for ex-vivo gene therapy to repair articular cartilage defects. Osteoarthritis Cartilage. 2001 Apr; 9(3):248-56. Goomer RS, Deftos LJ, Terkeltaub R, Maris T, Lee MC, Harwood FL, Amiel D. PMID: 11300748.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    164. Winter rheumatology symposium. IDrugs. 2001 Apr; 4(4):386-7. Terkeltaub R. PMID: 16015471.
      View in: PubMed   Mentions:    Fields:    
    165. Parathyroid hormone-related protein induces interleukin 8 production by prostate cancer cells via a novel intracrine mechanism not mediated by its classical nuclear localization sequence. Cancer Res. 2001 Mar 01; 61(5):2282-8. Gujral A, Burton DW, Terkeltaub R, Deftos LJ. PMID: 11280799.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    166. PC-1 nucleoside triphosphate pyrophosphohydrolase deficiency in idiopathic infantile arterial calcification. Am J Pathol. 2001 Feb; 158(2):543-54. Rutsch F, Vaingankar S, Johnson K, Goldfine I, Maddux B, Schauerte P, Kalhoff H, Sano K, Boisvert WA, Superti-Furga A, Terkeltaub R. PMID: 11159191.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansCells
    167. Syndrome X and gout: benefits of altered diet. Curr Rheumatol Rep. 2001 Feb; 3(1):9-10. Terkeltaub R. PMID: 11177765.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    168. The tetrabasic KKKK(147-150) motif determines intracrine regulatory effects of PthrP 1-173 on chondrocyte PPi metabolism and matrix synthesis. Endocrinology. 2000 Dec; 141(12):4613-22. Goomer RS, Johnson KA, Burton DW, Amiel D, Maris TM, Gurjal A, Deftost LJ, Terkeltaub R. PMID: 11108275.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    169. Osteoblast tissue-nonspecific alkaline phosphatase antagonizes and regulates PC-1. Am J Physiol Regul Integr Comp Physiol. 2000 Oct; 279(4):R1365-77. Johnson KA, Hessle L, Vaingankar S, Wennberg C, Mauro S, Narisawa S, Goding JW, Sano K, Millan JL, Terkeltaub R. PMID: 11004006.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    170. Mitochondrial oxidative phosphorylation is a downstream regulator of nitric oxide effects on chondrocyte matrix synthesis and mineralization. Arthritis Rheum. 2000 Jul; 43(7):1560-70. Johnson K, Jung A, Murphy A, Andreyev A, Dykens J, Terkeltaub R. PMID: 10902761.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    171. Lyme disease 2000. Emerging zoonoses complicate patient work-up and treatment. Geriatrics. 2000 Jul; 55(7):34-5, 39-40, 43-4 passim. Terkeltaub RA. PMID: 10909405.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    172. Extracellular signal-regulated kinase 1/extracellular signal-regulated kinase 2 mitogen-activated protein kinase signaling and activation of activator protein 1 and nuclear factor kappaB transcription factors play central roles in interleukin-8 expression stimulated by monosodium urate monohydrate and calcium pyrophosphate crystals in monocytic cells. Arthritis Rheum. 2000 May; 43(5):1145-55. Liu R, O'Connell M, Johnson K, Pritzker K, Mackman N, Terkeltaub R. PMID: 10817569.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    173. Interleukin-8 and its receptor CXCR2 in atherosclerosis. Immunol Res. 2000; 21(2-3):129-37. Boisvert WA, Curtiss LK, Terkeltaub RA. PMID: 10852110.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimals
    174. Clinical trials review: crystal deposition diseases. Curr Rheumatol Rep. 1999 Dec; 1(2):97-100. Terkeltaub RA. PMID: 11123021.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    175. New developments in the pathogenesis of articular cartilage calcification. Curr Rheumatol Rep. 1999 Dec; 1(2):121-7. Karpouzas GA, Terkeltaub RA. PMID: 11123025.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    176. IL-10: An "immunologic scalpel" for atherosclerosis? Arterioscler Thromb Vasc Biol. 1999 Dec; 19(12):2823-5. Terkeltaub RA. PMID: 10591656.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    177. Differential mechanisms of inorganic pyrophosphate production by plasma cell membrane glycoprotein-1 and B10 in chondrocytes. Arthritis Rheum. 1999 Sep; 42(9):1986-97. Johnson K, Vaingankar S, Chen Y, Moffa A, Goldring MB, Sano K, Jin-Hua P, Sali A, Goding J, Terkeltaub R. PMID: 10513816.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    178. Noninvasive evaluation of adult onset myopathy from carnitine palmitoyl transferase II deficiency using proton magnetic resonance spectroscopy. J Rheumatol. 1999 Aug; 26(8):1757-63. Videen JS, Haseler LJ, Karpinski NC, Terkeltaub RA. PMID: 10451074.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    179. Matrix vesicle plasma cell membrane glycoprotein-1 regulates mineralization by murine osteoblastic MC3T3 cells. J Bone Miner Res. 1999 Jun; 14(6):883-92. Johnson K, Moffa A, Chen Y, Pritzker K, Goding J, Terkeltaub R. PMID: 10352096.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    180. Parathyroid hormone-related proteins is abundant in osteoarthritic cartilage, and the parathyroid hormone-related protein 1-173 isoform is selectively induced by transforming growth factor beta in articular chondrocytes and suppresses generation of extracellular inorganic pyrophosphate. Arthritis Rheum. 1998 Dec; 41(12):2152-64. Terkeltaub R, Lotz M, Johnson K, Deng D, Hashimoto S, Goldring MB, Burton D, Deftos LJ. PMID: 9870872.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    181. Chemokines and atherosclerosis. Curr Opin Lipidol. 1998 Oct; 9(5):397-405. Terkeltaub R, Boisvert WA, Curtiss LK. PMID: 9812193.
      View in: PubMed   Mentions: 25     Fields:    Translation:Cells
    182. Bone morphogenetic proteins and bFGF exert opposing regulatory effects on PTHrP expression and inorganic pyrophosphate elaboration in immortalized murine endochondral hypertrophic chondrocytes (MCT cells). J Bone Miner Res. 1998 Jun; 13(6):931-41. Terkeltaub RA, Johnson K, Rohnow D, Goomer R, Burton D, Deftos LJ. PMID: 9626624.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    183. The murine homolog of the interleukin-8 receptor CXCR-2 is essential for the occurrence of neutrophilic inflammation in the air pouch model of acute urate crystal-induced gouty synovitis. Arthritis Rheum. 1998 May; 41(5):900-9. Terkeltaub R, Baird S, Sears P, Santiago R, Boisvert W. PMID: 9588743.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    184. Chondrocyte-derived apoptotic bodies and calcification of articular cartilage. Proc Natl Acad Sci U S A. 1998 Mar 17; 95(6):3094-9. Hashimoto S, Ochs RL, Rosen F, Quach J, McCabe G, Solan J, Seegmiller JE, Terkeltaub R, Lotz M. PMID: 9501221.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    185. Ecto-phosphodiesterase/pyrophosphatase of lymphocytes and non-lymphoid cells: structure and function of the PC-1 family. Immunol Rev. 1998 Feb; 161:11-26. Goding JW, Terkeltaub R, Maurice M, Deterre P, Sali A, Belli SI. PMID: 9553761.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    186. A leukocyte homologue of the IL-8 receptor CXCR-2 mediates the accumulation of macrophages in atherosclerotic lesions of LDL receptor-deficient mice. J Clin Invest. 1998 Jan 15; 101(2):353-63. Boisvert WA, Santiago R, Curtiss LK, Terkeltaub RA. PMID: 9435307.
      View in: PubMed   Mentions: 86     Fields:    Translation:AnimalsCells
    187. Differential effects of aging on human chondrocyte responses to transforming growth factor beta: increased pyrophosphate production and decreased cell proliferation. Arthritis Rheum. 1997 Jul; 40(7):1275-81. Rosen F, McCabe G, Quach J, Solan J, Terkeltaub R, Seegmiller JE, Lotz M. PMID: 9214428.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    188. Hypercalcemia and systemic lupus erythematosus. Arthritis Rheum. 1996 Dec; 39(12):2066-9. Deftos LJ, Burton DW, Baird SM, Terkeltaub RA. PMID: 8961913.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    189. Antiphospholipid antibodies are directed against epitopes of oxidized phospholipids. Recognition of cardiolipin by monoclonal antibodies to epitopes of oxidized low density lipoprotein. J Clin Invest. 1996 Aug 01; 98(3):815-25. Hörkkö S, Miller E, Dudl E, Reaven P, Curtiss LK, Zvaifler NJ, Terkeltaub R, Pierangeli SS, Branch DW, Palinski W, Witztum JL. PMID: 8698874.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    190. Expression of the nucleoside triphosphate pyrophosphohydrolase PC-1 is induced by basic fibroblast growth factor (bFGF) and modulated by activation of the protein kinase A and C pathways in osteoblast-like osteosarcoma cells. J Bone Miner Res. 1996 Feb; 11(2):183-92. Solan JL, Deftos LJ, Goding JW, Terkeltaub RA. PMID: 8822342.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    191. Interleukin 1 beta suppresses transforming growth factor-induced inorganic pyrophosphate (PPi) production and expression of the PPi-generating enzyme PC-1 in human chondrocytes. Proc Natl Acad Sci U S A. 1995 Oct 24; 92(22):10364-8. Lotz M, Rosen F, McCabe G, Quach J, Blanco F, Dudler J, Solan J, Goding J, Seegmiller JE, Terkeltaub R. PMID: 7479785.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    192. Gout: questions that still need to be answered. Ann Rheum Dis. 1995 Feb; 54(2):79-81. Terkeltaub RA. PMID: 7702409.
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    193. The immortalized chondrocyte: art without sacrifice. J Clin Invest. 1994 Dec; 94(6):2173. Terkeltaub RA. PMID: 7989569.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    194. Expression of the murine plasma cell nucleotide pyrophosphohydrolase PC-1 is shared by human liver, bone, and cartilage cells. Regulation of PC-1 expression in osteosarcoma cells by transforming growth factor-beta. J Clin Invest. 1994 Aug; 94(2):560-7. Huang R, Rosenbach M, Vaughn R, Provvedini D, Rebbe N, Hickman S, Goding J, Terkeltaub R. PMID: 8040311.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    195. Causal link between nucleotide pyrophosphohydrolase overactivity and increased intracellular inorganic pyrophosphate generation demonstrated by transfection of cultured fibroblasts and osteoblasts with plasma cell membrane glycoprotein-1. Relevance to calcium pyrophosphate dihydrate deposition disease. Arthritis Rheum. 1994 Jun; 37(6):934-41. Terkeltaub R, Rosenbach M, Fong F, Goding J. PMID: 8003067.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    196. Role of the mevalonate pathway of isoprenoid synthesis in IL-8 generation by activated monocytic cells. J Leukoc Biol. 1994 Jun; 55(6):749-55. Terkeltaub R, Solan J, Barry M, Santoro D, Bokoch GM. PMID: 8195701.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    197. Oxidized LDL enhances lipopolysaccharide-induced tissue factor expression in human adherent monocytes. Arterioscler Thromb. 1994 May; 14(5):790-7. Brand K, Banka CL, Mackman N, Terkeltaub RA, Fan ST, Curtiss LK. PMID: 8172855.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    198. Oxidized LDL induces monocytic cell expression of interleukin-8, a chemokine with T-lymphocyte chemotactic activity. Arterioscler Thromb. 1994 Jan; 14(1):47-53. Terkeltaub R, Banka CL, Solan J, Santoro D, Brand K, Curtiss LK. PMID: 8274477.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    199. Gout and mechanisms of crystal-induced inflammation. Curr Opin Rheumatol. 1993 Jul; 5(4):510-6. Terkeltaub RA. PMID: 8357747.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    200. Monocyte chemoattractant protein-1 (MCP-1) expression in human articular cartilage. Induction by peptide regulatory factors and differential effects of dexamethasone and retinoic acid. J Clin Invest. 1992 Aug; 90(2):488-96. Villiger PM, Terkeltaub R, Lotz M. PMID: 1365641.
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    201. Production of monocyte chemoattractant protein-1 by inflamed synovial tissue and cultured synoviocytes. J Immunol. 1992 Jul 15; 149(2):722-7. Villiger PM, Terkeltaub R, Lotz M. PMID: 1624809.
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    202. Cartilage and joint inflammation. Regulation of IL-8 expression by human articular chondrocytes. J Immunol. 1992 Jan 15; 148(2):466-73. Lotz M, Terkeltaub R, Villiger PM. PMID: 1729366.
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    203. What stops a gouty attack? J Rheumatol. 1992 Jan; 19(1):8-10. Terkeltaub RA. PMID: 1556704.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    204. Monocyte-derived neutrophil chemotactic factor/interleukin-8 is a potential mediator of crystal-induced inflammation. Arthritis Rheum. 1991 Jul; 34(7):894-903. Terkeltaub R, Zachariae C, Santoro D, Martin J, Peveri P, Matsushima K. PMID: 2059236.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    205. Mechanism of neutrophil activation by an unopsonized inflammatory particulate. Monosodium urate crystals induce pertussis toxin-insensitive hydrolysis of phosphatidylinositol 4,5-bisphosphate. J Immunol. 1991 Jun 15; 146(12):4289-94. Onello E, Traynor-Kaplan A, Sklar L, Terkeltaub R. PMID: 1645760.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    206. Apolipoprotein (apo) E inhibits the capacity of monosodium urate crystals to stimulate neutrophils. Characterization of intraarticular apo E and demonstration of apo E binding to urate crystals in vivo. J Clin Invest. 1991 Jan; 87(1):20-6. Terkeltaub RA, Dyer CA, Martin J, Curtiss LK. PMID: 1985096.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    207. Glycosaminoglycans alter the capacity of low density lipoprotein to bind to monosodium urate crystals. J Rheumatol. 1990 Sep; 17(9):1211-6. Terkeltaub R, Martin J, Curtiss LK, Ginsberg MH. PMID: 2290164.
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    208. Nasal cocaine abuse causing an aggressive midline intranasal and pharyngeal destructive process mimicking midline reticulosis and limited Wegener's granulomatosis. J Rheumatol. 1990 Jun; 17(6):838-40. Daggett RB, Haghighi P, Terkeltaub RA. PMID: 2388208.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    209. Neutrophil activation by inflammatory microcrystals of monosodium urate monohydrate utilizes pertussis toxin-insensitive and -sensitive pathways. J Immunol. 1990 Apr 01; 144(7):2719-24. Terkeltaub RA, Sklar LA, Mueller H. PMID: 2108211.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    210. The effects of gamma-interferon on human peripheral blood monocyte/macrophage-mediated bone particle degradation. Bone Miner. 1990 Feb; 8(2):131-43. Terkeltaub R, Firestein GS, Kornbluth RS, Martin J, Curran D, Manolagas S. PMID: 2106359.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    211. Inflammatory microcrystals stimulate interleukin-6 production and secretion by human monocytes and synoviocytes. Arthritis Rheum. 1989 Nov; 32(11):1443-52. Guerne PA, Terkeltaub R, Zuraw B, Lotz M. PMID: 2554932.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    212. Acute monoarthritis associated with intracellular positively birefringent Maltese cross appearing spherules. J Rheumatol. 1989 Mar; 16(3):394-6. Gardner GC, Terkeltaub RA. PMID: 2542545.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    213. Serum and plasma inhibit neutrophil stimulation by hydroxyapatite crystals. Evidence that serum alpha 2-HS glycoprotein is a potent and specific crystal-bound inhibitor. Arthritis Rheum. 1988 Sep; 31(9):1081-9. Terkeltaub RA, Santoro DA, Mandel G, Mandel N. PMID: 2844196.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    214. The inflammatory reaction to crystals. Rheum Dis Clin North Am. 1988 Aug; 14(2):353-64. Terkeltaub RA, Ginsberg MH. PMID: 3051154.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    215. Carpal alterations in adult-onset Still disease, juvenile chronic arthritis, and adult-onset rheumatoid arthritis: comparative study. Radiology. 1987 Nov; 165(2):545-8. Björkengren AG, Pathria MN, Sartoris DJ, Terkeltaub R, Esdaile JM, Weisman M, Resnick D. PMID: 3659381.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    216. Apolipoprotein B mediates the capacity of low density lipoprotein to suppress neutrophil stimulation by particulates. J Biol Chem. 1986 Nov 25; 261(33):15662-7. Terkeltaub R, Martin J, Curtiss LK, Ginsberg MH. PMID: 3096995.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    217. Low density lipoprotein inhibits the physical interaction of phlogistic crystals and inflammatory cells. Arthritis Rheum. 1986 Mar; 29(3):363-70. Terkeltaub R, Smeltzer D, Curtiss LK, Ginsberg MH. PMID: 3964313.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    218. Lipoproteins containing apoprotein B are a major regulator of neutrophil responses to monosodium urate crystals. J Clin Invest. 1984 Jun; 73(6):1719-30. Terkeltaub R, Curtiss LK, Tenner AJ, Ginsberg MH. PMID: 6725556.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    219. An immunogenetic study of older age onset rheumatoid arthritis. J Rheumatol. 1984 Apr; 11(2):147-9. Terkeltaub R, Décary F, Esdaile J. PMID: 6610048.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    220. Molecular mechanisms of gouty arthritis: new insights into an old disease. Surv Synth Pathol Res. 1984; 3(5):386-96. Terkeltaub R, Ginsberg MH. PMID: 6395263.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    221. Vasculitis as a presenting manifestation of primary biliary cirrhosis: a case report. Clin Exp Rheumatol. 1984 Jan-Mar; 2(1):67-73. Terkeltaub R, Esdaile JM, Bruneau C, Danoff D, Watters AK. PMID: 6532613.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    222. A clinical study of older age rheumatoid arthritis with comparison to a younger onset group. J Rheumatol. 1983 Jun; 10(3):418-24. Terkeltaub R, Esdaile J, Décary F, Tannenbaum H. PMID: 6411919.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    223. Plasma protein binding by monosodium urate crystals. Analysis by two-dimensional gel electrophoresis. Arthritis Rheum. 1983 Jun; 26(6):775-83. Terkeltaub R, Tenner AJ, Kozin F, Ginsberg MH. PMID: 6305372.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    224. HLA-Bw35 and prognosis in adult Still's disease. Arthritis Rheum. 1981 Dec; 24(12):1469-72. Terkeltaub R, Esdaile JM, Décary F, Harth M, Lister J, Lapointe N. PMID: 6976785.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    225. Prospective evaluation of sacroiliac scintigraphy in chronic inflammatory back pain. Arthritis Rheum. 1980 Sep; 23(9):998-1003. Esdaile JM, Rosenthall L, Terkeltaub R, Kloiber R. PMID: 7417363.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
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