Loading...

Terkeltaub, Robert Dr.

Title(s)Professor, Medicine
SchoolRheumatology
Phone858-552-8585
vCardDownload vCard

    Collapse Biography 
    Collapse Education and Training
    McGill University, Montreal, CanadaMD1976Medicine
    McGill University, Montreal, CanadaDCS1972Biology

    Collapse Overview 
    Collapse Overview
    Research Interests
    Cartilage nucleotide metabolism and disease; the regulation of proinflammatory cytokine expression in macrophages.

    Collapse Research 
    Collapse Research Activities and Funding
    Novel Synovial Role in Pathogenesis of Gout
    NIH/NIAMS R21AR075990Aug 1, 2019 - Jul 31, 2021
    Role: Principal Investigator
    Rheumatic Diseases Research Training Grant
    NIH/NIAMS T32AR064194May 9, 2013 - Apr 30, 2024
    Role: Principal Investigator
    Innate Inflammation in Osteoarthritis
    VA I01BX001660Apr 1, 2012 - Mar 31, 2021
    Role: Principal Investigator
    Transglutaminase 2 in Arterial Calcification and Atherosclerosis
    NIH/NHLBI R01HL087252May 15, 2008 - Dec 31, 2012
    Role: Principal Investigator
    Chondrocyte S100/Calgranulins and RAGE in Osteoarthritis
    NIH/NIAMS R01AR054135Jun 1, 2006 - May 31, 2010
    Role: Principal Investigator
    ANK and Joint Ankylosis in Spondylitis
    NIH/NIAMS R01AR049366Jan 1, 2005 - Nov 30, 2008
    Role: Principal Investigator
    Molecular Mechanisms in Arterial Calcification
    NIH/NHLBI R01HL077360Jul 1, 2004 - Jun 30, 2014
    Role: Principal Investigator
    PTHRP 1 to 173 IN CHONDROCYTES
    NIH/NIAMS R01AR047347Apr 6, 2001 - Jan 31, 2006
    Role: Principal Investigator
    MULTIPURPOSE ARTHRITIS &MUSCULOSKELETAL DISEASE CENTER
    NIH/NIAMS P60AR040770Aug 1, 1991 - Feb 28, 2002
    Role: Co-Investigator
    Studies of Joint Aging and Osteoarthritis
    NIH P01AG007996Dec 1, 1988 - Apr 30, 2017
    Role: Co-Investigator
    LOW DENSITY LIPOPROTEIN AND INFLAMMATION
    NIH/NIDDK R01DK036702Jul 1, 1985 - Jun 30, 1996
    Role: Principal Investigator
    LOW DENSITY LIPOPROTEINS AND GOUT
    NIH/NIADDK R23AM036702Jul 1, 1985 - Jun 30, 1988
    Role: Principal Investigator
    LOW DENSITY LIPOPROTEINS AND GOUT
    NIH/NIDDK R23DK036702Jul 1, 1985 - Jun 30, 1988
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Choi H, Neogi T, Stamp L, Dalbeth N, Terkeltaub R. Reply. Arthritis Rheumatol. 2019 Aug 05. PMID: 31379125.
      View in: PubMed
    2. Yokose C, McCormick N, Chen C, Neogi T, Chaisson C, Terkeltaub R, Hunter DJ, Zhang Y, Choi H. Risk of gout flares after vaccination: a prospective case cross-over study. Ann Rheum Dis. 2019 Jul 31. PMID: 31366470.
      View in: PubMed
    3. Wei J, Neogi T, Terkeltaub R, Fenves AZ, Zeng C, Misra D, Choi HK, Lei G, Zhang Y. Thiazide diuretics and risk of knee replacement surgery among patients with knee osteoarthritis: a general population-based cohort study. Osteoarthritis Cartilage. 2019 Jun 08. PMID: 31181261.
      View in: PubMed
    4. Sanchez-Lopez E, Zhong Z, Stubelius A, Sweeney SR, Booshehri LM, Antonucci L, Liu-Bryan R, Lodi A, Terkeltaub R, Lacal JC, Murphy AN, Hoffman HM, Tiziani S, Guma M, Karin M. Choline Uptake and Metabolism Modulate Macrophage IL-1ß and IL-18 Production. Cell Metab. 2019 Jun 04; 29(6):1350-1362.e7. PMID: 30982734.
      View in: PubMed
    5. Serrano RL, Yu W, Graham RM, Bryan RL, Terkeltaub R. A vascular smooth muscle cell X-box binding protein 1 and transglutaminase 2 regulatory circuit limits neointimal hyperplasia. PLoS One. 2019; 14(4):e0212235. PMID: 30943188.
      View in: PubMed
    6. Zhang M, Zhang Y, Terkeltaub R, Chen C, Neogi T. Effect of Dietary and Supplemental Omega-3 Polyunsaturated Fatty Acids on Risk of Recurrent Gout Flares. Arthritis Rheumatol. 2019 Mar 25. PMID: 30908893.
      View in: PubMed
    7. Bursill D, Taylor WJ, Terkeltaub R, Kuwabara M, Merriman TR, Grainger R, Pineda C, Louthrenoo W, Edwards NL, Andrés M, Vargas-Santos AB, Roddy E, Pascart T, Lin CT, Perez-Ruiz F, Tedeschi SK, Kim SC, Harrold LR, McCarthy G, Kumar N, Chapman PT, Tausche AK, Vazquez-Mellado J, Gutierrez M, da Rocha Castelar-Pinheiro G, Richette P, Pascual E, Fisher MC, Burgos-Vargas R, Robinson PC, Singh JA, Jansen TL, Saag KG, Slot O, Uhlig T, Solomon DH, Keenan RT, Scire CA, Biernat-Kaluza E, Dehlin M, Nuki G, Schlesinger N, Janssen M, Stamp LK, Sivera F, Reginato AM, Jacobsson L, Lioté F, Ea HK, Rosenthal A, Bardin T, Choi HK, Hershfield MS, Czegley C, Choi SJ, Dalbeth N. Gout, Hyperuricemia, and Crystal-Associated Disease Network Consensus Statement Regarding Labels and Definitions for Disease Elements in Gout. Arthritis Care Res (Hoboken). 2019 Mar; 71(3):427-434. PMID: 29799677.
      View in: PubMed
    8. Choi H, Neogi T, Stamp L, Dalbeth N, Terkeltaub R. Reply. Arthritis Rheumatol. 2019 Mar; 71(3):481-482. PMID: 30295436.
      View in: PubMed
    9. Dalbeth N, Jones G, Terkeltaub R, Khanna D, Fung M, Baumgartner S, Perez-Ruiz F. Efficacy and safety during extended treatment of lesinurad in combination with febuxostat in patients with tophaceous gout: CRYSTAL extension study. Arthritis Res Ther. 2019 Jan 07; 21(1):8. PMID: 30616614.
      View in: PubMed
    10. Terkeltaub R, Saag KG, Goldfarb DS, Baumgartner S, Schechter BM, Valiyil R, Jalal D, Pillinger M, White WB. Integrated safety studies of the urate reabsorption inhibitor lesinurad in treatment of gout. Rheumatology (Oxford). 2019 Jan 01; 58(1):61-69. PMID: 30124941.
      View in: PubMed
    11. Choi H, Neogi T, Stamp L, Dalbeth N, Terkeltaub R. New Perspectives in Rheumatology: Implications of the Cardiovascular Safety of Febuxostat and Allopurinol in Patients With Gout and Cardiovascular Morbidities Trial and the Associated Food and Drug Administration Public Safety Alert. Arthritis Rheumatol. 2018 Nov; 70(11):1702-1709. PMID: 29869840.
      View in: PubMed
    12. Jin Y, Cong Q, Gvozdenovic-Jeremic J, Hu J, Zhang Y, Terkeltaub R, Yang Y. Enpp1 inhibits ectopic joint calcification and maintains articular chondrocytes by repressing hedgehog signaling. Development. 2018 09 20; 145(18). PMID: 30111653.
      View in: PubMed
    13. McWherter C, Choi YJ, Serrano RL, Mahata SK, Terkeltaub R, Liu-Bryan R. Arhalofenate acid inhibits monosodium urate crystal-induced inflammatory responses through activation of AMP-activated protein kinase (AMPK) signaling. Arthritis Res Ther. 2018 09 06; 20(1):204. PMID: 30189890.
      View in: PubMed
    14. Chen LY, Wang Y, Terkeltaub R, Liu-Bryan R. Activation of AMPK-SIRT3 signaling is chondroprotective by preserving mitochondrial DNA integrity and function. Osteoarthritis Cartilage. 2018 Nov; 26(11):1539-1550. PMID: 30031925.
      View in: PubMed
    15. Chen LY, Lotz M, Terkeltaub R, Liu-Bryan R. Modulation of matrix metabolism by ATP-citrate lyase in articular chondrocytes. J Biol Chem. 2018 08 03; 293(31):12259-12270. PMID: 29929979.
      View in: PubMed
    16. Abhishek A, Neogi T, Choi H, Doherty M, Rosenthal AK, Terkeltaub R. Review: Unmet Needs and the Path Forward in Joint Disease Associated With Calcium Pyrophosphate Crystal Deposition. Arthritis Rheumatol. 2018 Aug; 70(8):1182-1191. PMID: 29609209.
      View in: PubMed
    17. Serrano RL, Chen LY, Lotz MK, Liu-Bryan R, Terkeltaub R. Impaired Proteasomal Function in Human Osteoarthritic Chondrocytes Can Contribute to Decreased Levels of SOX9 and Aggrecan. Arthritis Rheumatol. 2018 Jul; 70(7):1030-1041. PMID: 29457374.
      View in: PubMed
    18. Shadyab AH, Terkeltaub R, Kooperberg C, Reiner A, Eaton CB, Jackson RD, Krok-Schoen JL, Salem RM, LaCroix AZ. Prospective associations of C-reactive protein (CRP) levels and CRP genetic risk scores with risk of total knee and hip replacement for osteoarthritis in a diverse cohort. Osteoarthritis Cartilage. 2018 Aug; 26(8):1038-1044. PMID: 29758352.
      View in: PubMed
    19. Bursill D, Taylor WJ, Terkeltaub R, Dalbeth N. The nomenclature of the basic disease elements of gout: A content analysis of contemporary medical journals. Semin Arthritis Rheum. 2018 12; 48(3):456-461. PMID: 29706241.
      View in: PubMed
    20. Zeng C, Wei J, Terkeltaub R, Yang T, Choi HK, Wang YL, Xie DX, Hunter DJ, Zhang Y, Li H, Cui Y, Li LJ, Lei GH. Dose-response relationship between lower serum magnesium level and higher prevalence of knee chondrocalcinosis. Arthritis Res Ther. 2017 Oct 24; 19(1):236. PMID: 29065924.
      View in: PubMed
    21. Terkeltaub R. What makes gouty inflammation so variable? BMC Med. 2017 08 18; 15(1):158. PMID: 28818081.
      View in: PubMed
    22. Dalbeth N, Bardin T, Doherty M, Lioté F, Richette P, Saag KG, So AK, Stamp LK, Choi HK, Terkeltaub R. Discordant American College of Physicians and international rheumatology guidelines for gout management: consensus statement of the Gout, Hyperuricemia and Crystal-Associated Disease Network (G-CAN). Nat Rev Rheumatol. 2017 Sep; 13(9):561-568. PMID: 28794514.
      View in: PubMed
    23. Dalbeth N, Jones G, Terkeltaub R, Khanna D, Kopicko J, Bhakta N, Adler S, Fung M, Storgard C, Baumgartner S, Perez-Ruiz F. Lesinurad, a Selective Uric Acid Reabsorption Inhibitor, in Combination With Febuxostat in Patients With Tophaceous Gout: Findings of a Phase III Clinical Trial. Arthritis Rheumatol. 2017 09; 69(9):1903-1913. PMID: 28597604.
      View in: PubMed
    24. Harrold LR, Etzel CJ, Gibofsky A, Kremer JM, Pillinger MH, Saag KG, Schlesinger N, Terkeltaub R, Cox V, Greenberg JD. Sex differences in gout characteristics: tailoring care for women and men. BMC Musculoskelet Disord. 2017 03 14; 18(1):108. PMID: 28292303.
      View in: PubMed
    25. Merriman T, Terkeltaub R. PPARGC1B: insight into the expression of the gouty inflammation phenotype: PPARGC1B and gouty inflammation. Rheumatology (Oxford). 2017 03 01; 56(3):323-325. PMID: 28003496.
      View in: PubMed
    26. Dalbeth N, Choi HK, Terkeltaub R. Review: Gout: A Roadmap to Approaches for Improving Global Outcomes. Arthritis Rheumatol. 2017 01; 69(1):22-34. PMID: 27389665.
      View in: PubMed
    27. Terkeltaub R. Emerging uricosurics for gout. Expert Rev Clin Pharmacol. 2017 03; 10(3):247-249. PMID: 27937050.
      View in: PubMed
    28. Wu Y, Chen K, Terkeltaub R. Systematic review and quality analysis of emerging diagnostic measures for calcium pyrophosphate crystal deposition disease. RMD Open. 2016; 2(2):e000339. PMID: 27933211.
      View in: PubMed
    29. Miner JN, Tan PK, Hyndman D, Liu S, Iverson C, Nanavati P, Hagerty DT, Manhard K, Shen Z, Girardet JL, Yeh LT, Terkeltaub R, Quart B. Erratum to: Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney. Arthritis Res Ther. 2016 10 12; 18(1):236. PMID: 27733209.
      View in: PubMed
    30. Miner JN, Tan PK, Hyndman D, Liu S, Iverson C, Nanavati P, Hagerty DT, Manhard K, Shen Z, Girardet JL, Yeh LT, Terkeltaub R, Quart B. Lesinurad, a novel, oral compound for gout, acts to decrease serum uric acid through inhibition of urate transporters in the kidney. Arthritis Res Ther. 2016 10 03; 18(1):214. PMID: 27716403.
      View in: PubMed
    31. de Lautour H, Taylor WJ, Adebajo A, Alten R, Burgos-Vargas R, Chapman P, Cimmino MA, da Rocha Castelar Pinheiro G, Day R, Harrold LR, Helliwell P, Janssen M, Kerr G, Kavanaugh A, Khanna D, Khanna PP, Lin C, Louthrenoo W, McCarthy G, Vazquez-Mellado J, Mikuls TR, Neogi T, Ogdie A, Perez-Ruiz F, Schlesinger N, Ralph Schumacher H, Scirè CA, Singh JA, Sivera F, Slot O, Stamp LK, Tausche AK, Terkeltaub R, Uhlig T, van de Laar M, White D, Yamanaka H, Zeng X, Dalbeth N. Development of Preliminary Remission Criteria for Gout Using Delphi and 1000Minds Consensus Exercises. Arthritis Care Res (Hoboken). 2016 05; 68(5):667-72. PMID: 26414176.
      View in: PubMed
    32. Lu N, Rai SK, Terkeltaub R, Kim SC, Menendez ME, Choi HK. Racial disparities in the risk of Stevens-Johnson Syndrome and toxic epidermal necrolysis as urate-lowering drug adverse events in the United States. Semin Arthritis Rheum. 2016 10; 46(2):253-8. PMID: 27217070; PMCID: PMC5035554 [Available on 10/01/17].
      View in: PubMed, PubMed Central
    33. Haslberger A, Terkeltaub R. Editorial: Can GPR43 Sensing of Short-Chain Fatty Acids Unchain Inflammasome-Driven Arthritis? Arthritis Rheumatol. 2015 Jun; 67(6):1419-23. PMID: 25914362; PMCID: PMC4446232.
      View in: PubMed, PubMed Central
    34. Wang Y, Zhao X, Lotz M, Terkeltaub R, Liu-Bryan R. Mitochondrial biogenesis is impaired in osteoarthritis chondrocytes but reversible via peroxisome proliferator-activated receptor ? coactivator 1a. Arthritis Rheumatol. 2015 May; 67(8):2141-53. PMID: 25940958; PMCID: PMC4519411.
      View in: PubMed, PubMed Central
    35. Zhao X, Petursson F, Viollet B, Lotz M, Terkeltaub R, Liu-Bryan R. Peroxisome proliferator-activated receptor ? coactivator 1a and FoxO3A mediate chondroprotection by AMP-activated protein kinase. Arthritis Rheumatol. 2014 Nov; 66(11):3073-82. PMID: 25047750; PMCID: PMC4343036.
      View in: PubMed, PubMed Central
    36. Wang Y, Viollet B, Terkeltaub R, Liu-Bryan R. AMP-activated protein kinase suppresses urate crystal-induced inflammation and transduces colchicine effects in macrophages. Ann Rheum Dis. 2016 Jan; 75(1):286-94. PMID: 25362043.
      View in: PubMed
    37. Liu-Bryan R, Terkeltaub R. Emerging regulators of the inflammatory process in osteoarthritis. Nat Rev Rheumatol. 2015 Jan; 11(1):35-44. PMID: 25266449; PMCID: PMC4374654.
      View in: PubMed, PubMed Central
    38. Terkeltaub R. Apolipoprotein a-I at the interface of vascular inflammation and arthritis. Arterioscler Thromb Vasc Biol. 2014 Mar; 34(3):474-6. PMID: 24554604; PMCID: PMC3975075.
      View in: PubMed, PubMed Central
    39. Khanna PP, Gladue HS, Singh MK, FitzGerald JD, Bae S, Prakash S, Kaldas M, Gogia M, Berrocal V, Townsend W, Terkeltaub R, Khanna D. Treatment of acute gout: a systematic review. Semin Arthritis Rheum. 2014 Aug; 44(1):31-8. PMID: 24650777.
      View in: PubMed
    40. Serrano RL, Yu W, Terkeltaub R. Mono-allelic and bi-allelic ENPP1 deficiency promote post-injury neointimal hyperplasia associated with increased C/EBP homologous protein expression. Atherosclerosis. 2014 Apr; 233(2):493-502. PMID: 24530784; PMCID: PMC4386864.
      View in: PubMed, PubMed Central
    41. Terkeltaub R. Gout: multinational gout guidelines: how do we move beyond 'déjà vu'? Nat Rev Rheumatol. 2013 Oct; 9(10):567-9. PMID: 24045709.
      View in: PubMed
    42. Petursson F, Husa M, June R, Lotz M, Terkeltaub R, Liu-Bryan R. Linked decreases in liver kinase B1 and AMP-activated protein kinase activity modulate matrix catabolic responses to biomechanical injury in chondrocytes. Arthritis Res Ther. 2013 Jul 25; 15(4):R77. PMID: 23883619; PMCID: PMC3979085.
      View in: PubMed, PubMed Central
    43. Terkeltaub R. Are cherries now ripe for use as a complementary therapeutic in gout? Appraisal of the state of evidence. Evid Based Med. 2013 Dec; 18(6):230-1. PMID: 23416419.
      View in: PubMed
    44. Prowse RL, Dalbeth N, Kavanaugh A, Adebajo AO, Gaffo AL, Terkeltaub R, Mandell BF, Suryana BP, Goldenstein-Schainberg C, Diaz-Torne C, Khanna D, Lioté F, Mccarthy G, Kerr GS, Yamanaka H, Janssens H, Baraf HF, Chen JH, Vazquez-Mellado J, Harrold LR, Stamp LK, Van De Laar MA, Janssen M, Doherty M, Boers M, Edwards NL, Gow P, Chapman P, Khanna P, Helliwell PS, Grainger R, Schumacher HR, Neogi T, Jansen TL, Louthrenoo W, Sivera F, Taylor WJ, Alten R. A delphi exercise to identify characteristic features of gout - opinions from patients and physicians, the first stage in developing new classification criteria. J Rheumatol. 2013 Apr; 40(4):498-505. PMID: 23418379.
      View in: PubMed
    45. Terkeltaub RA, Schumacher HR, Carter JD, Baraf HS, Evans RR, Wang J, King-Davis S, Weinstein SP. Rilonacept in the treatment of acute gouty arthritis: a randomized, controlled clinical trial using indomethacin as the active comparator. Arthritis Res Ther. 2013 Feb 01; 15(1):R25. PMID: 23375025; PMCID: PMC3672764.
      View in: PubMed, PubMed Central
    46. Husa M, Petursson F, Lotz M, Terkeltaub R, Liu-Bryan R. C/EBP homologous protein drives pro-catabolic responses in chondrocytes. Arthritis Res Ther. 2013; 15(6):R218. PMID: 24351550; PMCID: PMC3978428.
      View in: PubMed, PubMed Central
    47. Terkeltaub R. Imaging joints for calcium pyrophosphate crystal deposition: a knock to the knees. Arthritis Res Ther. 2012 Dec 27; 14(6):128. PMID: 23270654; PMCID: PMC3674586.
      View in: PubMed, PubMed Central
    48. Khanna D, Fitzgerald JD, Khanna PP, Bae S, Singh MK, Neogi T, Pillinger MH, Merill J, Lee S, Prakash S, Kaldas M, Gogia M, Perez-Ruiz F, Taylor W, Lioté F, Choi H, Singh JA, Dalbeth N, Kaplan S, Niyyar V, Jones D, Yarows SA, Roessler B, Kerr G, King C, Levy G, Furst DE, Edwards NL, Mandell B, Schumacher HR, Robbins M, Wenger N, Terkeltaub R. 2012 American College of Rheumatology guidelines for management of gout. Part 1: systematic nonpharmacologic and pharmacologic therapeutic approaches to hyperuricemia. Arthritis Care Res (Hoboken). 2012 Oct; 64(10):1431-46. PMID: 23024028; PMCID: PMC3683400.
      View in: PubMed, PubMed Central
    49. Schumacher HR, Evans RR, Saag KG, Clower J, Jennings W, Weinstein SP, Yancopoulos GD, Wang J, Terkeltaub R. Rilonacept (interleukin-1 trap) for prevention of gout flares during initiation of uric acid-lowering therapy: results from a phase III randomized, double-blind, placebo-controlled, confirmatory efficacy study. Arthritis Care Res (Hoboken). 2012 Oct; 64(10):1462-70. PMID: 22549879.
      View in: PubMed
    50. Khanna D, Khanna PP, Fitzgerald JD, Singh MK, Bae S, Neogi T, Pillinger MH, Merill J, Lee S, Prakash S, Kaldas M, Gogia M, Perez-Ruiz F, Taylor W, Lioté F, Choi H, Singh JA, Dalbeth N, Kaplan S, Niyyar V, Jones D, Yarows SA, Roessler B, Kerr G, King C, Levy G, Furst DE, Edwards NL, Mandell B, Schumacher HR, Robbins M, Wenger N, Terkeltaub R. 2012 American College of Rheumatology guidelines for management of gout. Part 2: therapy and antiinflammatory prophylaxis of acute gouty arthritis. Arthritis Care Res (Hoboken). 2012 Oct; 64(10):1447-61. PMID: 23024029; PMCID: PMC3662546.
      View in: PubMed, PubMed Central
    51. Liu-Bryan R, Terkeltaub R. The growing array of innate inflammatory ignition switches in osteoarthritis. Arthritis Rheum. 2012 Jul; 64(7):2055-8. PMID: 22488656; PMCID: PMC3711830.
      View in: PubMed, PubMed Central
    52. Dammanahalli KJ, Stevens S, Terkeltaub R. Vanin-1 pantetheinase drives smooth muscle cell activation in post-arterial injury neointimal hyperplasia. PLoS One. 2012; 7(6):e39106. PMID: 22720042; PMCID: PMC3374784.
      View in: PubMed, PubMed Central
    53. Gruber BL, Couto AR, Armas JB, Brown MA, Finzel K, Terkeltaub RA. Novel ANKH amino terminus mutation (Pro5Ser) associated with early-onset calcium pyrophosphate disease with associated phosphaturia. J Clin Rheumatol. 2012 Jun; 18(4):192-5. PMID: 22647861.
      View in: PubMed
    54. Yu W, Liu-Bryan R, Stevens S, Damanahalli JK, Terkeltaub R. RAGE signaling mediates post-injury arterial neointima formation by suppression of liver kinase B1 and AMPK activity. Atherosclerosis. 2012 Jun; 222(2):417-25. PMID: 22552116; PMCID: PMC3361645.
      View in: PubMed, PubMed Central
    55. Schumacher HR, Sundy JS, Terkeltaub R, Knapp HR, Mellis SJ, Stahl N, Yancopoulos GD, Soo Y, King-Davis S, Weinstein SP, Radin AR. Rilonacept (interleukin-1 trap) in the prevention of acute gout flares during initiation of urate-lowering therapy: results of a phase II randomized, double-blind, placebo-controlled trial. Arthritis Rheum. 2012 Mar; 64(3):876-84. PMID: 22223180.
      View in: PubMed
    56. Neogi T, George J, Rekhraj S, Struthers AD, Choi H, Terkeltaub RA. Are either or both hyperuricemia and xanthine oxidase directly toxic to the vasculature? A critical appraisal. Arthritis Rheum. 2012 Feb; 64(2):327-38. PMID: 21953377; PMCID: PMC3265683.
      View in: PubMed, PubMed Central
    57. Nitschke Y, Baujat G, Botschen U, Wittkampf T, du Moulin M, Stella J, Le Merrer M, Guest G, Lambot K, Tazarourte-Pinturier MF, Chassaing N, Roche O, Feenstra I, Loechner K, Deshpande C, Garber SJ, Chikarmane R, Steinmann B, Shahinyan T, Martorell L, Davies J, Smith WE, Kahler SG, McCulloch M, Wraige E, Loidi L, Höhne W, Martin L, Hadj-Rabia S, Terkeltaub R, Rutsch F. Generalized arterial calcification of infancy and pseudoxanthoma elasticum can be caused by mutations in either ENPP1 or ABCC6. Am J Hum Genet. 2012 Jan 13; 90(1):25-39. PMID: 22209248; PMCID: PMC3257960.
      View in: PubMed, PubMed Central
    58. Nitschke Y, Weissen-Plenz G, Terkeltaub R, Rutsch F. Npp1 promotes atherosclerosis in ApoE knockout mice. J Cell Mol Med. 2011 Nov; 15(11):2273-83. PMID: 21477221; PMCID: PMC3154990.
      View in: PubMed, PubMed Central
    59. Rutsch F, Nitschke Y, Terkeltaub R. Genetics in arterial calcification: pieces of a puzzle and cogs in a wheel. Circ Res. 2011 Aug 19; 109(5):578-92. PMID: 21852556.
      View in: PubMed
    60. Terkeltaub RA, Furst DE, Digiacinto JL, Kook KA, Davis MW. Novel evidence-based colchicine dose-reduction algorithm to predict and prevent colchicine toxicity in the presence of cytochrome P450 3A4/P-glycoprotein inhibitors. Arthritis Rheum. 2011 Aug; 63(8):2226-37. PMID: 21480191.
      View in: PubMed
    61. Terkeltaub R, Yang B, Lotz M, Liu-Bryan R. Chondrocyte AMP-activated protein kinase activity suppresses matrix degradation responses to proinflammatory cytokines interleukin-1ß and tumor necrosis factor a. Arthritis Rheum. 2011 Jul; 63(7):1928-37. PMID: 21400477; PMCID: PMC3128233.
      View in: PubMed, PubMed Central
    62. Khanna D, Sarkin AJ, Khanna PP, Shieh MM, Kavanaugh AF, Terkeltaub RA, Lee SJ, Singh JA, Hirsch JD. Minimally important differences of the gout impact scale in a randomized controlled trial. Rheumatology (Oxford). 2011 Jul; 50(7):1331-6. PMID: 21372003; PMCID: PMC3307519.
      View in: PubMed, PubMed Central
    63. Cecil DL, Terkeltaub RA. Arterial calcification is driven by RAGE in Enpp1-/- mice. J Vasc Res. 2011; 48(3):227-35. PMID: 21099228; PMCID: PMC2997448.
      View in: PubMed, PubMed Central
    64. Neogi T, Terkeltaub R, Ellison RC, Hunt S, Zhang Y. Serum urate is not associated with coronary artery calcification: the NHLBI Family Heart Study. J Rheumatol. 2011 Jan; 38(1):111-7. PMID: 20889594; PMCID: PMC3119360.
      View in: PubMed, PubMed Central
    65. Singh JA, Sarkin A, Shieh M, Khanna D, Terkeltaub R, Lee SJ, Kavanaugh A, Hirsch JD. Health care utilization in patients with gout. Semin Arthritis Rheum. 2011 Jun; 40(6):501-11. PMID: 20828793.
      View in: PubMed
    66. Sarkin AJ, Levack AE, Shieh MM, Kavanaugh AF, Khanna D, Singh JA, Terkeltaub RA, Lee SJ, Hirsch JD. Predictors of doctor-rated and patient-rated gout severity: gout impact scales improve assessment. J Eval Clin Pract. 2010 Dec; 16(6):1244-7. PMID: 20722884.
      View in: PubMed
    67. Lotz MK, Otsuki S, Grogan SP, Sah R, Terkeltaub R, D'Lima D. Cartilage cell clusters. Arthritis Rheum. 2010 Aug; 62(8):2206-18. PMID: 20506158.
      View in: PubMed
    68. Liu-Bryan R, Terkeltaub R. Chondrocyte innate immune myeloid differentiation factor 88-dependent signaling drives procatabolic effects of the endogenous Toll-like receptor 2/Toll-like receptor 4 ligands low molecular weight hyaluronan and high mobility group box chromosomal protein 1 in mice. Arthritis Rheum. 2010 Jul; 62(7):2004-12. PMID: 20506365; PMCID: PMC2902571.
      View in: PubMed, PubMed Central
    69. Husa M, Liu-Bryan R, Terkeltaub R. Shifting HIFs in osteoarthritis. Nat Med. 2010 Jun; 16(6):641-4. PMID: 20526316; PMCID: PMC2917906.
      View in: PubMed, PubMed Central
    70. Terkeltaub RA, Furst DE, Bennett K, Kook KA, Crockett RS, Davis MW. High versus low dosing of oral colchicine for early acute gout flare: Twenty-four-hour outcome of the first multicenter, randomized, double-blind, placebo-controlled, parallel-group, dose-comparison colchicine study. Arthritis Rheum. 2010 Apr; 62(4):1060-8. PMID: 20131255.
      View in: PubMed
    71. Hirsch JD, Terkeltaub R, Khanna D, Singh J, Sarkin A, Shieh M, Kavanaugh A, Lee SJ. Gout disease-specific quality of life and the association with gout characteristics. Patient Relat Outcome Meas. 2010 Mar 01; 2010:1-8. PMID: 21686040.
      View in: PubMed
    72. Terkeltaub R. Update on gout: new therapeutic strategies and options. Nat Rev Rheumatol. 2010 Jan; 6(1):30-8. PMID: 20046204.
      View in: PubMed
    73. Polewski MD, Johnson KA, Foster M, Millán JL, Terkeltaub R. Inorganic pyrophosphatase induces type I collagen in osteoblasts. Bone. 2010 Jan; 46(1):81-90. PMID: 19733704; PMCID: PMC2818162.
      View in: PubMed, PubMed Central
    74. Terkeltaub R, Sundy JS, Schumacher HR, Murphy F, Bookbinder S, Biedermann S, Wu R, Mellis S, Radin A. The interleukin 1 inhibitor rilonacept in treatment of chronic gouty arthritis: results of a placebo-controlled, monosequence crossover, non-randomised, single-blind pilot study. Ann Rheum Dis. 2009 Oct; 68(10):1613-7. PMID: 19635719; PMCID: PMC2732898.
      View in: PubMed, PubMed Central
    75. Terkeltaub R. Gout. Novel therapies for treatment of gout and hyperuricemia. Arthritis Res Ther. 2009; 11(4):236. PMID: 19664185.
      View in: PubMed
    76. Terkeltaub R, Zelman D, Scavulli J, Perez-Ruiz F, Lioté F. Gout Study Group: update on hyperuricemia and gout. Joint Bone Spine. 2009 Jul; 76(4):444-6. PMID: 19559637.
      View in: PubMed
    77. Torres R, Macdonald L, Croll SD, Reinhardt J, Dore A, Stevens S, Hylton DM, Rudge JS, Liu-Bryan R, Terkeltaub RA, Yancopoulos GD, Murphy AJ. Hyperalgesia, synovitis and multiple biomarkers of inflammation are suppressed by interleukin 1 inhibition in a novel animal model of gouty arthritis. Ann Rheum Dis. 2009 Oct; 68(10):1602-8. PMID: 19528034.
      View in: PubMed
    78. Cecil DL, Appleton CT, Polewski MD, Mort JS, Schmidt AM, Bendele A, Beier F, Terkeltaub R. The pattern recognition receptor CD36 is a chondrocyte hypertrophy marker associated with suppression of catabolic responses and promotion of repair responses to inflammatory stimuli. J Immunol. 2009 Apr 15; 182(8):5024-31. PMID: 19342682; PMCID: PMC2698125.
      View in: PubMed, PubMed Central
    79. Terkeltaub RA. A sugar transporter regulates serum urate levels: implications for prevention and management of hyperuricemia in gout. Curr Rheumatol Rep. 2009 Apr; 11(2):83-6. PMID: 19296879.
      View in: PubMed
    80. Chao J, Terkeltaub R. A critical reappraisal of allopurinol dosing, safety, and efficacy for hyperuricemia in gout. Curr Rheumatol Rep. 2009 Apr; 11(2):135-40. PMID: 19296886.
      View in: PubMed
    81. Huebner JL, Johnson KA, Kraus VB, Terkeltaub RA. Transglutaminase 2 is a marker of chondrocyte hypertrophy and osteoarthritis severity in the Hartley guinea pig model of knee OA. Osteoarthritis Cartilage. 2009 Aug; 17(8):1056-64. PMID: 19328881; PMCID: PMC3249463.
      View in: PubMed, PubMed Central
    82. Lee SJ, Hirsch JD, Terkeltaub R, Khanna D, Singh JA, Sarkin A, Kavanaugh A. Perceptions of disease and health-related quality of life among patients with gout. Rheumatology (Oxford). 2009 May; 48(5):582-6. PMID: 19307257; PMCID: PMC2722803.
      View in: PubMed, PubMed Central
    83. Neogi T, Ellison RC, Hunt S, Terkeltaub R, Felson DT, Zhang Y. Serum uric acid is associated with carotid plaques: the National Heart, Lung, and Blood Institute Family Heart Study. J Rheumatol. 2009 Feb; 36(2):378-84. PMID: 19012359; PMCID: PMC2731484.
      View in: PubMed, PubMed Central
    84. Terkeltaub R. Macrophage glucocorticoid receptors join the intercellular dialogue in atherosclerotic lesion calcification. Arterioscler Thromb Vasc Biol. 2008 Dec; 28(12):2096-8. PMID: 19020314; PMCID: PMC2746738.
      View in: PubMed, PubMed Central
    85. Rutsch F, Böyer P, Nitschke Y, Ruf N, Lorenz-Depierieux B, Wittkampf T, Weissen-Plenz G, Fischer RJ, Mughal Z, Gregory JW, Davies JH, Loirat C, Strom TM, Schnabel D, Nürnberg P, Terkeltaub R. Hypophosphatemia, hyperphosphaturia, and bisphosphonate treatment are associated with survival beyond infancy in generalized arterial calcification of infancy. Circ Cardiovasc Genet. 2008 Dec; 1(2):133-40. PMID: 20016754; PMCID: PMC2794045.
      View in: PubMed, PubMed Central
    86. Terkeltaub RA. Colchicine update: 2008. Semin Arthritis Rheum. 2009 Jun; 38(6):411-9. PMID: 18973929.
      View in: PubMed
    87. Hirsch JD, Lee SJ, Terkeltaub R, Khanna D, Singh J, Sarkin A, Harvey J, Kavanaugh A. Evaluation of an instrument assessing influence of Gout on health-related quality of life. J Rheumatol. 2008 Dec; 35(12):2406-14. PMID: 18925685.
      View in: PubMed
    88. Cecil DL, Terkeltaub R. Transamidation by transglutaminase 2 transforms S100A11 calgranulin into a procatabolic cytokine for chondrocytes. J Immunol. 2008 Jun 15; 180(12):8378-85. PMID: 18523305; PMCID: PMC2577366.
      View in: PubMed, PubMed Central
    89. Johnson KA, Rose DM, Terkeltaub RA. Factor XIIIA mobilizes transglutaminase 2 to induce chondrocyte hypertrophic differentiation. J Cell Sci. 2008 Jul 01; 121(Pt 13):2256-64. PMID: 18544639; PMCID: PMC2615675.
      View in: PubMed, PubMed Central
    90. Millán JL, Narisawa S, Lemire I, Loisel TP, Boileau G, Leonard P, Gramatikova S, Terkeltaub R, Camacho NP, McKee MD, Crine P, Whyte MP. Enzyme replacement therapy for murine hypophosphatasia. J Bone Miner Res. 2008 Jun; 23(6):777-87. PMID: 18086009; PMCID: PMC2652241.
      View in: PubMed, PubMed Central
    91. Johnson KA, Polewski M, Terkeltaub RA. Transglutaminase 2 is central to induction of the arterial calcification program by smooth muscle cells. Circ Res. 2008 Mar 14; 102(5):529-37. PMID: 18202319; PMCID: PMC2652242.
      View in: PubMed, PubMed Central
    92. Johnson KA, Yao W, Lane NE, Naquet P, Terkeltaub RA. Vanin-1 pantetheinase drives increased chondrogenic potential of mesenchymal precursors in ank/ank mice. Am J Pathol. 2008 Feb; 172(2):440-53. PMID: 18187567; PMCID: PMC2312367.
      View in: PubMed, PubMed Central
    93. Terkeltaub R. Learning how and when to employ uricase as bridge therapy in refractory gout. J Rheumatol. 2007 Oct; 34(10):1955-8. PMID: 17924606.
      View in: PubMed
    94. Hough TA, Polewski M, Johnson K, Cheeseman M, Nolan PM, Vizor L, Rastan S, Boyde A, Pritzker K, Hunter AJ, Fisher EM, Terkeltaub R, Brown SD. Novel mouse model of autosomal semidominant adult hypophosphatasia has a splice site mutation in the tissue nonspecific alkaline phosphatase gene Akp2. J Bone Miner Res. 2007 Sep; 22(9):1397-407. PMID: 17539739.
      View in: PubMed
    95. Hennigan S, Terkeltaub R. Last call for alcohol in gout? Curr Rheumatol Rep. 2007 Jun; 9(3):229-30. PMID: 17531176.
      View in: PubMed
    96. Strnad P, Harada M, Siegel M, Terkeltaub RA, Graham RM, Khosla C, Omary MB. Transglutaminase 2 regulates mallory body inclusion formation and injury-associated liver enlargement. Gastroenterology. 2007 Apr; 132(4):1515-26. PMID: 17408647.
      View in: PubMed
    97. Mitsuyama H, Healey RM, Terkeltaub RA, Coutts RD, Amiel D. Calcification of human articular knee cartilage is primarily an effect of aging rather than osteoarthritis. Osteoarthritis Cartilage. 2007 May; 15(5):559-65. PMID: 17276093; PMCID: PMC2707182.
      View in: PubMed, PubMed Central
    98. Scott P, Ma H, Viriyakosol S, Terkeltaub R, Liu-Bryan R. Engagement of CD14 mediates the inflammatory potential of monosodium urate crystals. J Immunol. 2006 Nov 01; 177(9):6370-8. PMID: 17056568.
      View in: PubMed
    99. Zhang Y, Terkeltaub R, Nevitt M, Xu L, Neogi T, Aliabadi P, Niu J, Felson DT. Lower prevalence of chondrocalcinosis in Chinese subjects in Beijing than in white subjects in the United States: the Beijing Osteoarthritis Study. Arthritis Rheum. 2006 Nov; 54(11):3508-12. PMID: 17075853.
      View in: PubMed
    100. Rose DM, Sydlaske AD, Agha-Babakhani A, Johnson K, Terkeltaub R. Transglutaminase 2 limits murine peritoneal acute gout-like inflammation by regulating macrophage clearance of apoptotic neutrophils. Arthritis Rheum. 2006 Oct; 54(10):3363-71. PMID: 17009310.
      View in: PubMed
    101. Harmey D, Johnson KA, Zelken J, Camacho NP, Hoylaerts MF, Noda M, Terkeltaub R, Millán JL. Elevated skeletal osteopontin levels contribute to the hypophosphatasia phenotype in Akp2(-/-) mice. J Bone Miner Res. 2006 Sep; 21(9):1377-86. PMID: 16939396.
      View in: PubMed
    102. Terkeltaub R. Physiologic and pathologic functions of the NPP nucleotide pyrophosphatase/phosphodiesterase family focusing on NPP1 in calcification. Purinergic Signal. 2006 Jun; 2(2):371-7. PMID: 18404477; PMCID: PMC2254483.
      View in: PubMed, PubMed Central
    103. Lee SJ, Terkeltaub RA. New developments in clinically relevant mechanisms and treatment of hyperuricemia. Curr Rheumatol Rep. 2006 Jun; 8(3):224-30. PMID: 16901081.
      View in: PubMed
    104. Neogi T, Nevitt M, Niu J, LaValley MP, Hunter DJ, Terkeltaub R, Carbone L, Chen H, Harris T, Kwoh K, Guermazi A, Felson DT. Lack of association between chondrocalcinosis and increased risk of cartilage loss in knees with osteoarthritis: results of two prospective longitudinal magnetic resonance imaging studies. Arthritis Rheum. 2006 Jun; 54(6):1822-8. PMID: 16729275.
      View in: PubMed
    105. Terkeltaub R, Bushinsky DA, Becker MA. Recent developments in our understanding of the renal basis of hyperuricemia and the development of novel antihyperuricemic therapeutics. Arthritis Res Ther. 2006; 8 Suppl 1:S4. PMID: 16820043; PMCID: PMC3226109.
      View in: PubMed, PubMed Central
    106. Cronstein BN, Terkeltaub R. The inflammatory process of gout and its treatment. Arthritis Res Ther. 2006; 8 Suppl 1:S3. PMID: 16820042; PMCID: PMC3226108.
      View in: PubMed, PubMed Central
    107. Boisvert WA, Rose DM, Johnson KA, Fuentes ME, Lira SA, Curtiss LK, Terkeltaub RA. Up-regulated expression of the CXCR2 ligand KC/GRO-alpha in atherosclerotic lesions plays a central role in macrophage accumulation and lesion progression. Am J Pathol. 2006 Apr; 168(4):1385-95. PMID: 16565511; PMCID: PMC1606562.
      View in: PubMed, PubMed Central
    108. Neogi T, Booth SL, Zhang YQ, Jacques PF, Terkeltaub R, Aliabadi P, Felson DT. Low vitamin K status is associated with osteoarthritis in the hand and knee. Arthritis Rheum. 2006 Apr; 54(4):1255-61. PMID: 16572460.
      View in: PubMed
    109. Lee SJ, Terkeltaub RA, Kavanaugh A. Recent developments in diet and gout. Curr Opin Rheumatol. 2006 Mar; 18(2):193-8. PMID: 16462528.
      View in: PubMed
    110. Terkeltaub R. Hyperuricemia treatment: is creatinine clearance a safer allopurinol dosing meter than plasma creatinine levels? Nat Clin Pract Rheumatol. 2006 Feb; 2(2):68-9. PMID: 16932657.
      View in: PubMed
    111. Liu-Bryan R, Terkeltaub R. Evil humors take their toll as innate immunity makes gouty joints TREM-ble. Arthritis Rheum. 2006 Feb; 54(2):383-6. PMID: 16447213.
      View in: PubMed
    112. Boisvert WA, Rose DM, Boullier A, Quehenberger O, Sydlaske A, Johnson KA, Curtiss LK, Terkeltaub R. Leukocyte transglutaminase 2 expression limits atherosclerotic lesion size. Arterioscler Thromb Vasc Biol. 2006 Mar; 26(3):563-9. PMID: 16410462.
      View in: PubMed
    113. Terkeltaub R. Gout in 2006: the perfect storm. Bull NYU Hosp Jt Dis. 2006; 64(1-2):82-6. PMID: 17121496.
      View in: PubMed
    114. Cecil DL, Johnson K, Rediske J, Lotz M, Schmidt AM, Terkeltaub R. Inflammation-induced chondrocyte hypertrophy is driven by receptor for advanced glycation end products. J Immunol. 2005 Dec 15; 175(12):8296-302. PMID: 16339570.
      View in: PubMed
    115. Liu-Bryan R, Scott P, Sydlaske A, Rose DM, Terkeltaub R. Innate immunity conferred by Toll-like receptors 2 and 4 and myeloid differentiation factor 88 expression is pivotal to monosodium urate monohydrate crystal-induced inflammation. Arthritis Rheum. 2005 Sep; 52(9):2936-46. PMID: 16142712.
      View in: PubMed
    116. Anderson HC, Harmey D, Camacho NP, Garimella R, Sipe JB, Tague S, Bi X, Johnson K, Terkeltaub R, Millán JL. Sustained osteomalacia of long bones despite major improvement in other hypophosphatasia-related mineral deficits in tissue nonspecific alkaline phosphatase/nucleotide pyrophosphatase phosphodiesterase 1 double-deficient mice. Am J Pathol. 2005 Jun; 166(6):1711-20. PMID: 15920156; PMCID: PMC1602415.
      View in: PubMed, PubMed Central
    117. Wu CW, Terkeltaub R. What do epidemiologic studies tell us about hyperuricemia and cardiovascular disease and death? Curr Rheumatol Rep. 2005 Jun; 7(3):211-2. PMID: 15918997.
      View in: PubMed
    118. Wu CW, Terkeltaub R, Kalunian KC. Calcium-containing crystals and osteoarthritis: implications for the clinician. Curr Rheumatol Rep. 2005 Jun; 7(3):213-9. PMID: 15918998.
      View in: PubMed
    119. Burton DW, Foster M, Johnson KA, Hiramoto M, Deftos LJ, Terkeltaub R. Chondrocyte calcium-sensing receptor expression is up-regulated in early guinea pig knee osteoarthritis and modulates PTHrP, MMP-13, and TIMP-3 expression. Osteoarthritis Cartilage. 2005 May; 13(5):395-404. PMID: 15882563.
      View in: PubMed
    120. Liu-Bryan R, Pritzker K, Firestein GS, Terkeltaub R. TLR2 signaling in chondrocytes drives calcium pyrophosphate dihydrate and monosodium urate crystal-induced nitric oxide generation. J Immunol. 2005 Apr 15; 174(8):5016-23. PMID: 15814732.
      View in: PubMed
    121. Zhang Y, Johnson K, Russell RG, Wordsworth BP, Carr AJ, Terkeltaub RA, Brown MA. Association of sporadic chondrocalcinosis with a -4-basepair G-to-A transition in the 5'-untranslated region of ANKH that promotes enhanced expression of ANKH protein and excess generation of extracellular inorganic pyrophosphate. Arthritis Rheum. 2005 Apr; 52(4):1110-7. PMID: 15818664.
      View in: PubMed
    122. Rutsch F, Terkeltaub R. Deficiencies of physiologic calcification inhibitors and low-grade inflammation in arterial calcification: lessons for cartilage calcification. Joint Bone Spine. 2005 Mar; 72(2):110-8. PMID: 15797489.
      View in: PubMed
    123. Johnson KA, Terkeltaub RA. External GTP-bound transglutaminase 2 is a molecular switch for chondrocyte hypertrophic differentiation and calcification. J Biol Chem. 2005 Apr 15; 280(15):15004-12. PMID: 15691824.
      View in: PubMed
    124. Dong H, Maddux BA, Altomonte J, Meseck M, Accili D, Terkeltaub R, Johnson K, Youngren JF, Goldfine ID. Increased hepatic levels of the insulin receptor inhibitor, PC-1/NPP1, induce insulin resistance and glucose intolerance. Diabetes. 2005 Feb; 54(2):367-72. PMID: 15677494.
      View in: PubMed
    125. Johnson K, Terkeltaub R. Inorganic pyrophosphate (PPI) in pathologic calcification of articular cartilage. Front Biosci. 2005 Jan 01; 10:988-97. PMID: 15569637.
      View in: PubMed
    126. Cecil DL, Rose DM, Terkeltaub R, Liu-Bryan R. Role of interleukin-8 in PiT-1 expression and CXCR1-mediated inorganic phosphate uptake in chondrocytes. Arthritis Rheum. 2005 Jan; 52(1):144-54. PMID: 15641067.
      View in: PubMed
    127. Ruf N, Uhlenberg B, Terkeltaub R, Nürnberg P, Rutsch F. The mutational spectrum of ENPP1 as arising after the analysis of 23 unrelated patients with generalized arterial calcification of infancy (GACI). Hum Mutat. 2005 Jan; 25(1):98. PMID: 15605415.
      View in: PubMed
    128. Johnson K, Polewski M, van Etten D, Terkeltaub R. Chondrogenesis mediated by PPi depletion promotes spontaneous aortic calcification in NPP1-/- mice. Arterioscler Thromb Vasc Biol. 2005 Apr; 25(4):686-91. PMID: 15625282.
      View in: PubMed
    129. Tramontini N, Huber C, Liu-Bryan R, Terkeltaub RA, Kilgore KS. Central role of complement membrane attack complex in monosodium urate crystal-induced neutrophilic rabbit knee synovitis. Arthritis Rheum. 2004 Aug; 50(8):2633-9. PMID: 15334478.
      View in: PubMed
    130. Bieber JD, Terkeltaub RA. Gout: on the brink of novel therapeutic options for an ancient disease. Arthritis Rheum. 2004 Aug; 50(8):2400-14. PMID: 15334451.
      View in: PubMed
    131. Bieber J, Terkeltaub R. The role of hypertension in cyclosporine-induced hyperuricemia. Curr Rheumatol Rep. 2004 Jun; 6(3):215-6. PMID: 15134600.
      View in: PubMed
    132. Abreu M, Johnson K, Chung CB, De Lima JE, Trudell D, Terkeltaub R, Pe S, Resnick D. Calcification in calcium pyrophosphate dihydrate (CPPD) crystalline deposits in the knee: anatomic, radiographic, MR imaging, and histologic study in cadavers. Skeletal Radiol. 2004 Jul; 33(7):392-8. PMID: 15138720.
      View in: PubMed
    133. Johnson K, Terkeltaub R. Upregulated ank expression in osteoarthritis can promote both chondrocyte MMP-13 expression and calcification via chondrocyte extracellular PPi excess. Osteoarthritis Cartilage. 2004 Apr; 12(4):321-35. PMID: 15023384.
      View in: PubMed
    134. Harmey D, Hessle L, Narisawa S, Johnson KA, Terkeltaub R, Millán JL. Concerted regulation of inorganic pyrophosphate and osteopontin by akp2, enpp1, and ank: an integrated model of the pathogenesis of mineralization disorders. Am J Pathol. 2004 Apr; 164(4):1199-209. PMID: 15039209; PMCID: PMC1615351.
      View in: PubMed, PubMed Central
    135. Johnson K, Svensson CI, Etten DV, Ghosh SS, Murphy AN, Powell HC, Terkeltaub R. Mediation of spontaneous knee osteoarthritis by progressive chondrocyte ATP depletion in Hartley guinea pigs. Arthritis Rheum. 2004 Apr; 50(4):1216-25. PMID: 15077304.
      View in: PubMed
    136. Liu R, Lioté F, Rose DM, Merz D, Terkeltaub R. Proline-rich tyrosine kinase 2 and Src kinase signaling transduce monosodium urate crystal-induced nitric oxide production and matrix metalloproteinase 3 expression in chondrocytes. Arthritis Rheum. 2004 Jan; 50(1):247-58. PMID: 14730623.
      View in: PubMed
    137. Vaingankar SM, Fitzpatrick TA, Johnson K, Goding JW, Maurice M, Terkeltaub R. Subcellular targeting and function of osteoblast nucleotide pyrophosphatase phosphodiesterase 1. Am J Physiol Cell Physiol. 2004 May; 286(5):C1177-87. PMID: 15075217.
      View in: PubMed
    138. Schraufstatter IU, Trieu K, Zhao M, Rose DM, Terkeltaub RA, Burger M. IL-8-mediated cell migration in endothelial cells depends on cathepsin B activity and transactivation of the epidermal growth factor receptor. J Immunol. 2003 Dec 15; 171(12):6714-22. PMID: 14662875.
      View in: PubMed
    139. Terkeltaub RA. Questions & answers. What's the difference between gout and pseudogout? Health News. 2003 Dec; 9(12):16. PMID: 14679973.
      View in: PubMed
    140. Terkeltaub RA. Clinical practice. Gout. N Engl J Med. 2003 Oct 23; 349(17):1647-55. PMID: 14573737.
      View in: PubMed
    141. Merz D, Liu R, Johnson K, Terkeltaub R. IL-8/CXCL8 and growth-related oncogene alpha/CXCL1 induce chondrocyte hypertrophic differentiation. J Immunol. 2003 Oct 15; 171(8):4406-15. PMID: 14530367.
      View in: PubMed
    142. Rutsch F, Ruf N, Vaingankar S, Toliat MR, Suk A, Höhne W, Schauer G, Lehmann M, Roscioli T, Schnabel D, Epplen JT, Knisely A, Superti-Furga A, McGill J, Filippone M, Sinaiko AR, Vallance H, Hinrichs B, Smith W, Ferre M, Terkeltaub R, Nürnberg P. Mutations in ENPP1 are associated with 'idiopathic' infantile arterial calcification. Nat Genet. 2003 Aug; 34(4):379-81. PMID: 12881724.
      View in: PubMed
    143. Johnson K, Goding J, Van Etten D, Sali A, Hu SI, Farley D, Krug H, Hessle L, Millán JL, Terkeltaub R. Linked deficiencies in extracellular PP(i) and osteopontin mediate pathologic calcification associated with defective PC-1 and ANK expression. J Bone Miner Res. 2003 Jun; 18(6):994-1004. PMID: 12817751.
      View in: PubMed
    144. Pay S, Terkeltaub R. Calcium pyrophosphate dihydrate and hydroxyapatite crystal deposition in the joint: new developments relevant to the clinician. Curr Rheumatol Rep. 2003 Jun; 5(3):235-43. PMID: 12744817.
      View in: PubMed
    145. Johnson K, Farley D, Hu SI, Terkeltaub R. One of two chondrocyte-expressed isoforms of cartilage intermediate-layer protein functions as an insulin-like growth factor 1 antagonist. Arthritis Rheum. 2003 May; 48(5):1302-14. PMID: 12746903.
      View in: PubMed
    146. Rutsch F, Terkeltaub R. Parallels between arterial and cartilage calcification: what understanding artery calcification can teach us about chondrocalcinosis. Curr Opin Rheumatol. 2003 May; 15(3):302-10. PMID: 12707585.
      View in: PubMed
    147. Johnson KA, van Etten D, Nanda N, Graham RM, Terkeltaub RA. Distinct transglutaminase 2-independent and transglutaminase 2-dependent pathways mediate articular chondrocyte hypertrophy. J Biol Chem. 2003 May 23; 278(21):18824-32. PMID: 12606540.
      View in: PubMed
    148. Bakre MM, Zhu Y, Yin H, Burton DW, Terkeltaub R, Deftos LJ, Varner JA. Parathyroid hormone-related peptide is a naturally occurring, protein kinase A-dependent angiogenesis inhibitor. Nat Med. 2002 Sep; 8(9):995-1003. PMID: 12185361.
      View in: PubMed
    149. Hessle L, Johnson KA, Anderson HC, Narisawa S, Sali A, Goding JW, Terkeltaub R, Millan JL. Tissue-nonspecific alkaline phosphatase and plasma cell membrane glycoprotein-1 are central antagonistic regulators of bone mineralization. Proc Natl Acad Sci U S A. 2002 Jul 09; 99(14):9445-9. PMID: 12082181; PMCID: PMC123160.
      View in: PubMed, PubMed Central
    150. Terkeltaub R. Pseudogout, hypomagnesemia, and liver transplantation. Curr Rheumatol Rep. 2002 Jun; 4(3):243-4. PMID: 12010609.
      View in: PubMed
    151. Terkeltaub RA. What does cartilage calcification tell us about osteoarthritis? J Rheumatol. 2002 Mar; 29(3):411-5. PMID: 11908551.
      View in: PubMed
    152. Terkeltaub R, Johnson K, Murphy A, Ghosh S. Invited review: the mitochondrion in osteoarthritis. Mitochondrion. 2002 Feb; 1(4):301-19. PMID: 16120285.
      View in: PubMed
    153. Liu R, Aupperle K, Terkeltaub R. Src family protein tyrosine kinase signaling mediates monosodium urate crystal-induced IL-8 expression by monocytic THP-1 cells. J Leukoc Biol. 2001 Dec; 70(6):961-8. PMID: 11739559.
      View in: PubMed
    154. Johnson K, Pritzker K, Goding J, Terkeltaub R. The nucleoside triphosphate pyrophosphohydrolase isozyme PC-1 directly promotes cartilage calcification through chondrocyte apoptosis and increased calcium precipitation by mineralizing vesicles. J Rheumatol. 2001 Dec; 28(12):2681-91. PMID: 11764218.
      View in: PubMed
    155. Deftos LJ, Burton D, Hastings RH, Terkeltaub R, Hook VY. Comparative tissue distribution of the processing enzymes "prohormone thiol protease," and prohormone convertases 1 and 2, in human PTHrP-producing cell lines and mammalian neuroendocrine tissues. Endocrine. 2001 Jul; 15(2):217-24. PMID: 11720250.
      View in: PubMed
    156. Johnson K, Hashimoto S, Lotz M, Pritzker K, Terkeltaub R. Interleukin-1 induces pro-mineralizing activity of cartilage tissue transglutaminase and factor XIIIa. Am J Pathol. 2001 Jul; 159(1):149-63. PMID: 11438463.
      View in: PubMed
    157. Terkeltaub RA. Inorganic pyrophosphate generation and disposition in pathophysiology. Am J Physiol Cell Physiol. 2001 Jul; 281(1):C1-C11. PMID: 11401820.
      View in: PubMed
    158. Johnson K, Hashimoto S, Lotz M, Pritzker K, Goding J, Terkeltaub R. Up-regulated expression of the phosphodiesterase nucleotide pyrophosphatase family member PC-1 is a marker and pathogenic factor for knee meniscal cartilage matrix calcification. Arthritis Rheum. 2001 May; 44(5):1071-81. PMID: 11352238.
      View in: PubMed
    159. Goomer RS, Deftos LJ, Terkeltaub R, Maris T, Lee MC, Harwood FL, Amiel D. High-efficiency non-viral transfection of primary chondrocytes and perichondrial cells for ex-vivo gene therapy to repair articular cartilage defects. Osteoarthritis Cartilage. 2001 Apr; 9(3):248-56. PMID: 11300748.
      View in: PubMed
    160. Terkeltaub R. Winter rheumatology symposium. IDrugs. 2001 Apr; 4(4):386-7. PMID: 16015471.
      View in: PubMed
    161. Gujral A, Burton DW, Terkeltaub R, Deftos LJ. Parathyroid hormone-related protein induces interleukin 8 production by prostate cancer cells via a novel intracrine mechanism not mediated by its classical nuclear localization sequence. Cancer Res. 2001 Mar 01; 61(5):2282-8. PMID: 11280799.
      View in: PubMed
    162. Terkeltaub R. Syndrome X and gout: benefits of altered diet. Curr Rheumatol Rep. 2001 Feb; 3(1):9-10. PMID: 11177765.
      View in: PubMed
    163. Rutsch F, Vaingankar S, Johnson K, Goldfine I, Maddux B, Schauerte P, Kalhoff H, Sano K, Boisvert WA, Superti-Furga A, Terkeltaub R. PC-1 nucleoside triphosphate pyrophosphohydrolase deficiency in idiopathic infantile arterial calcification. Am J Pathol. 2001 Feb; 158(2):543-54. PMID: 11159191.
      View in: PubMed
    164. Goomer RS, Johnson KA, Burton DW, Amiel D, Maris TM, Gurjal A, Deftost LJ, Terkeltaub R. The tetrabasic KKKK(147-150) motif determines intracrine regulatory effects of PthrP 1-173 on chondrocyte PPi metabolism and matrix synthesis. Endocrinology. 2000 Dec; 141(12):4613-22. PMID: 11108275.
      View in: PubMed
    165. Johnson KA, Hessle L, Vaingankar S, Wennberg C, Mauro S, Narisawa S, Goding JW, Sano K, Millan JL, Terkeltaub R. Osteoblast tissue-nonspecific alkaline phosphatase antagonizes and regulates PC-1. Am J Physiol Regul Integr Comp Physiol. 2000 Oct; 279(4):R1365-77. PMID: 11004006.
      View in: PubMed
    166. Johnson K, Jung A, Murphy A, Andreyev A, Dykens J, Terkeltaub R. Mitochondrial oxidative phosphorylation is a downstream regulator of nitric oxide effects on chondrocyte matrix synthesis and mineralization. Arthritis Rheum. 2000 Jul; 43(7):1560-70. PMID: 10902761.
      View in: PubMed
    167. Terkeltaub RA. Lyme disease 2000. Emerging zoonoses complicate patient work-up and treatment. Geriatrics. 2000 Jul; 55(7):34-5, 39-40, 43-4 passim. PMID: 10909405.
      View in: PubMed
    168. Liu R, O'Connell M, Johnson K, Pritzker K, Mackman N, Terkeltaub R. Extracellular signal-regulated kinase 1/extracellular signal-regulated kinase 2 mitogen-activated protein kinase signaling and activation of activator protein 1 and nuclear factor kappaB transcription factors play central roles in interleukin-8 expression stimulated by monosodium urate monohydrate and calcium pyrophosphate crystals in monocytic cells. Arthritis Rheum. 2000 May; 43(5):1145-55. PMID: 10817569.
      View in: PubMed
    169. Boisvert WA, Curtiss LK, Terkeltaub RA. Interleukin-8 and its receptor CXCR2 in atherosclerosis. Immunol Res. 2000; 21(2-3):129-37. PMID: 10852110.
      View in: PubMed
    170. Karpouzas GA, Terkeltaub RA. New developments in the pathogenesis of articular cartilage calcification. Curr Rheumatol Rep. 1999 Dec; 1(2):121-7. PMID: 11123025.
      View in: PubMed
    171. Terkeltaub RA. Clinical trials review: crystal deposition diseases. Curr Rheumatol Rep. 1999 Dec; 1(2):97-100. PMID: 11123021.
      View in: PubMed
    172. Terkeltaub RA. IL-10: An "immunologic scalpel" for atherosclerosis? Arterioscler Thromb Vasc Biol. 1999 Dec; 19(12):2823-5. PMID: 10591656.
      View in: PubMed
    173. Johnson K, Vaingankar S, Chen Y, Moffa A, Goldring MB, Sano K, Jin-Hua P, Sali A, Goding J, Terkeltaub R. Differential mechanisms of inorganic pyrophosphate production by plasma cell membrane glycoprotein-1 and B10 in chondrocytes. Arthritis Rheum. 1999 Sep; 42(9):1986-97. PMID: 10513816.
      View in: PubMed
    174. Videen JS, Haseler LJ, Karpinski NC, Terkeltaub RA. Noninvasive evaluation of adult onset myopathy from carnitine palmitoyl transferase II deficiency using proton magnetic resonance spectroscopy. J Rheumatol. 1999 Aug; 26(8):1757-63. PMID: 10451074.
      View in: PubMed
    175. Johnson K, Moffa A, Chen Y, Pritzker K, Goding J, Terkeltaub R. Matrix vesicle plasma cell membrane glycoprotein-1 regulates mineralization by murine osteoblastic MC3T3 cells. J Bone Miner Res. 1999 Jun; 14(6):883-92. PMID: 10352096.
      View in: PubMed
    176. Terkeltaub R, Lotz M, Johnson K, Deng D, Hashimoto S, Goldring MB, Burton D, Deftos LJ. Parathyroid hormone-related proteins is abundant in osteoarthritic cartilage, and the parathyroid hormone-related protein 1-173 isoform is selectively induced by transforming growth factor beta in articular chondrocytes and suppresses generation of extracellular inorganic pyrophosphate. Arthritis Rheum. 1998 Dec; 41(12):2152-64. PMID: 9870872.
      View in: PubMed
    177. Terkeltaub R, Boisvert WA, Curtiss LK. Chemokines and atherosclerosis. Curr Opin Lipidol. 1998 Oct; 9(5):397-405. PMID: 9812193.
      View in: PubMed
    178. Terkeltaub RA, Johnson K, Rohnow D, Goomer R, Burton D, Deftos LJ. Bone morphogenetic proteins and bFGF exert opposing regulatory effects on PTHrP expression and inorganic pyrophosphate elaboration in immortalized murine endochondral hypertrophic chondrocytes (MCT cells). J Bone Miner Res. 1998 Jun; 13(6):931-41. PMID: 9626624.
      View in: PubMed
    179. Terkeltaub R, Baird S, Sears P, Santiago R, Boisvert W. The murine homolog of the interleukin-8 receptor CXCR-2 is essential for the occurrence of neutrophilic inflammation in the air pouch model of acute urate crystal-induced gouty synovitis. Arthritis Rheum. 1998 May; 41(5):900-9. PMID: 9588743.
      View in: PubMed
    180. Hashimoto S, Ochs RL, Rosen F, Quach J, McCabe G, Solan J, Seegmiller JE, Terkeltaub R, Lotz M. Chondrocyte-derived apoptotic bodies and calcification of articular cartilage. Proc Natl Acad Sci U S A. 1998 Mar 17; 95(6):3094-9. PMID: 9501221.
      View in: PubMed
    181. Goding JW, Terkeltaub R, Maurice M, Deterre P, Sali A, Belli SI. Ecto-phosphodiesterase/pyrophosphatase of lymphocytes and non-lymphoid cells: structure and function of the PC-1 family. Immunol Rev. 1998 Feb; 161:11-26. PMID: 9553761.
      View in: PubMed
    182. Boisvert WA, Santiago R, Curtiss LK, Terkeltaub RA. A leukocyte homologue of the IL-8 receptor CXCR-2 mediates the accumulation of macrophages in atherosclerotic lesions of LDL receptor-deficient mice. J Clin Invest. 1998 Jan 15; 101(2):353-63. PMID: 9435307.
      View in: PubMed
    183. Rosen F, McCabe G, Quach J, Solan J, Terkeltaub R, Seegmiller JE, Lotz M. Differential effects of aging on human chondrocyte responses to transforming growth factor beta: increased pyrophosphate production and decreased cell proliferation. Arthritis Rheum. 1997 Jul; 40(7):1275-81. PMID: 9214428.
      View in: PubMed
    184. Deftos LJ, Burton DW, Baird SM, Terkeltaub RA. Hypercalcemia and systemic lupus erythematosus. Arthritis Rheum. 1996 Dec; 39(12):2066-9. PMID: 8961913.
      View in: PubMed
    185. Hörkkö S, Miller E, Dudl E, Reaven P, Curtiss LK, Zvaifler NJ, Terkeltaub R, Pierangeli SS, Branch DW, Palinski W, Witztum JL. Antiphospholipid antibodies are directed against epitopes of oxidized phospholipids. Recognition of cardiolipin by monoclonal antibodies to epitopes of oxidized low density lipoprotein. J Clin Invest. 1996 Aug 01; 98(3):815-25. PMID: 8698874.
      View in: PubMed
    186. Solan JL, Deftos LJ, Goding JW, Terkeltaub RA. Expression of the nucleoside triphosphate pyrophosphohydrolase PC-1 is induced by basic fibroblast growth factor (bFGF) and modulated by activation of the protein kinase A and C pathways in osteoblast-like osteosarcoma cells. J Bone Miner Res. 1996 Feb; 11(2):183-92. PMID: 8822342.
      View in: PubMed
    187. Lotz M, Rosen F, McCabe G, Quach J, Blanco F, Dudler J, Solan J, Goding J, Seegmiller JE, Terkeltaub R. Interleukin 1 beta suppresses transforming growth factor-induced inorganic pyrophosphate (PPi) production and expression of the PPi-generating enzyme PC-1 in human chondrocytes. Proc Natl Acad Sci U S A. 1995 Oct 24; 92(22):10364-8. PMID: 7479785.
      View in: PubMed
    188. Terkeltaub RA. Gout: questions that still need to be answered. Ann Rheum Dis. 1995 Feb; 54(2):79-81. PMID: 7702409.
      View in: PubMed
    189. Terkeltaub RA. The immortalized chondrocyte: art without sacrifice. J Clin Invest. 1994 Dec; 94(6):2173. PMID: 7989569.
      View in: PubMed
    190. Huang R, Rosenbach M, Vaughn R, Provvedini D, Rebbe N, Hickman S, Goding J, Terkeltaub R. Expression of the murine plasma cell nucleotide pyrophosphohydrolase PC-1 is shared by human liver, bone, and cartilage cells. Regulation of PC-1 expression in osteosarcoma cells by transforming growth factor-beta. J Clin Invest. 1994 Aug; 94(2):560-7. PMID: 8040311.
      View in: PubMed
    191. Terkeltaub R, Rosenbach M, Fong F, Goding J. Causal link between nucleotide pyrophosphohydrolase overactivity and increased intracellular inorganic pyrophosphate generation demonstrated by transfection of cultured fibroblasts and osteoblasts with plasma cell membrane glycoprotein-1. Relevance to calcium pyrophosphate dihydrate deposition disease. Arthritis Rheum. 1994 Jun; 37(6):934-41. PMID: 8003067.
      View in: PubMed
    192. Terkeltaub R, Solan J, Barry M, Santoro D, Bokoch GM. Role of the mevalonate pathway of isoprenoid synthesis in IL-8 generation by activated monocytic cells. J Leukoc Biol. 1994 Jun; 55(6):749-55. PMID: 8195701.
      View in: PubMed
    193. Brand K, Banka CL, Mackman N, Terkeltaub RA, Fan ST, Curtiss LK. Oxidized LDL enhances lipopolysaccharide-induced tissue factor expression in human adherent monocytes. Arterioscler Thromb. 1994 May; 14(5):790-7. PMID: 8172855.
      View in: PubMed
    194. Terkeltaub R, Banka CL, Solan J, Santoro D, Brand K, Curtiss LK. Oxidized LDL induces monocytic cell expression of interleukin-8, a chemokine with T-lymphocyte chemotactic activity. Arterioscler Thromb. 1994 Jan; 14(1):47-53. PMID: 8274477.
      View in: PubMed
    195. Terkeltaub RA. Gout and mechanisms of crystal-induced inflammation. Curr Opin Rheumatol. 1993 Jul; 5(4):510-6. PMID: 8357747.
      View in: PubMed
    196. Villiger PM, Terkeltaub R, Lotz M. Monocyte chemoattractant protein-1 (MCP-1) expression in human articular cartilage. Induction by peptide regulatory factors and differential effects of dexamethasone and retinoic acid. J Clin Invest. 1992 Aug; 90(2):488-96. PMID: 1365641.
      View in: PubMed
    197. Villiger PM, Terkeltaub R, Lotz M. Production of monocyte chemoattractant protein-1 by inflamed synovial tissue and cultured synoviocytes. J Immunol. 1992 Jul 15; 149(2):722-7. PMID: 1624809.
      View in: PubMed
    198. Lotz M, Terkeltaub R, Villiger PM. Cartilage and joint inflammation. Regulation of IL-8 expression by human articular chondrocytes. J Immunol. 1992 Jan 15; 148(2):466-73. PMID: 1729366.
      View in: PubMed
    199. Terkeltaub RA. What stops a gouty attack? J Rheumatol. 1992 Jan; 19(1):8-10. PMID: 1556704.
      View in: PubMed
    200. Terkeltaub R, Zachariae C, Santoro D, Martin J, Peveri P, Matsushima K. Monocyte-derived neutrophil chemotactic factor/interleukin-8 is a potential mediator of crystal-induced inflammation. Arthritis Rheum. 1991 Jul; 34(7):894-903. PMID: 2059236.
      View in: PubMed
    201. Onello E, Traynor-Kaplan A, Sklar L, Terkeltaub R. Mechanism of neutrophil activation by an unopsonized inflammatory particulate. Monosodium urate crystals induce pertussis toxin-insensitive hydrolysis of phosphatidylinositol 4,5-bisphosphate. J Immunol. 1991 Jun 15; 146(12):4289-94. PMID: 1645760.
      View in: PubMed
    202. Terkeltaub RA, Dyer CA, Martin J, Curtiss LK. Apolipoprotein (apo) E inhibits the capacity of monosodium urate crystals to stimulate neutrophils. Characterization of intraarticular apo E and demonstration of apo E binding to urate crystals in vivo. J Clin Invest. 1991 Jan; 87(1):20-6. PMID: 1985096.
      View in: PubMed
    203. Terkeltaub R, Martin J, Curtiss LK, Ginsberg MH. Glycosaminoglycans alter the capacity of low density lipoprotein to bind to monosodium urate crystals. J Rheumatol. 1990 Sep; 17(9):1211-6. PMID: 2290164.
      View in: PubMed
    204. Daggett RB, Haghighi P, Terkeltaub RA. Nasal cocaine abuse causing an aggressive midline intranasal and pharyngeal destructive process mimicking midline reticulosis and limited Wegener's granulomatosis. J Rheumatol. 1990 Jun; 17(6):838-40. PMID: 2388208.
      View in: PubMed
    205. Terkeltaub RA, Sklar LA, Mueller H. Neutrophil activation by inflammatory microcrystals of monosodium urate monohydrate utilizes pertussis toxin-insensitive and -sensitive pathways. J Immunol. 1990 Apr 01; 144(7):2719-24. PMID: 2108211.
      View in: PubMed
    206. Terkeltaub R, Firestein GS, Kornbluth RS, Martin J, Curran D, Manolagas S. The effects of gamma-interferon on human peripheral blood monocyte/macrophage-mediated bone particle degradation. Bone Miner. 1990 Feb; 8(2):131-43. PMID: 2106359.
      View in: PubMed
    207. Guerne PA, Terkeltaub R, Zuraw B, Lotz M. Inflammatory microcrystals stimulate interleukin-6 production and secretion by human monocytes and synoviocytes. Arthritis Rheum. 1989 Nov; 32(11):1443-52. PMID: 2554932.
      View in: PubMed
    208. Gardner GC, Terkeltaub RA. Acute monoarthritis associated with intracellular positively birefringent Maltese cross appearing spherules. J Rheumatol. 1989 Mar; 16(3):394-6. PMID: 2542545.
      View in: PubMed
    209. Terkeltaub RA, Santoro DA, Mandel G, Mandel N. Serum and plasma inhibit neutrophil stimulation by hydroxyapatite crystals. Evidence that serum alpha 2-HS glycoprotein is a potent and specific crystal-bound inhibitor. Arthritis Rheum. 1988 Sep; 31(9):1081-9. PMID: 2844196.
      View in: PubMed
    210. Terkeltaub RA, Ginsberg MH. The inflammatory reaction to crystals. Rheum Dis Clin North Am. 1988 Aug; 14(2):353-64. PMID: 3051154.
      View in: PubMed
    211. Björkengren AG, Pathria MN, Sartoris DJ, Terkeltaub R, Esdaile JM, Weisman M, Resnick D. Carpal alterations in adult-onset Still disease, juvenile chronic arthritis, and adult-onset rheumatoid arthritis: comparative study. Radiology. 1987 Nov; 165(2):545-8. PMID: 3659381.
      View in: PubMed
    212. Terkeltaub R, Martin J, Curtiss LK, Ginsberg MH. Apolipoprotein B mediates the capacity of low density lipoprotein to suppress neutrophil stimulation by particulates. J Biol Chem. 1986 Nov 25; 261(33):15662-7. PMID: 3096995.
      View in: PubMed
    213. Terkeltaub R, Smeltzer D, Curtiss LK, Ginsberg MH. Low density lipoprotein inhibits the physical interaction of phlogistic crystals and inflammatory cells. Arthritis Rheum. 1986 Mar; 29(3):363-70. PMID: 3964313.
      View in: PubMed
    214. Terkeltaub R, Curtiss LK, Tenner AJ, Ginsberg MH. Lipoproteins containing apoprotein B are a major regulator of neutrophil responses to monosodium urate crystals. J Clin Invest. 1984 Jun; 73(6):1719-30. PMID: 6725556.
      View in: PubMed
    215. Terkeltaub R, Décary F, Esdaile J. An immunogenetic study of older age onset rheumatoid arthritis. J Rheumatol. 1984 Apr; 11(2):147-9. PMID: 6610048.
      View in: PubMed
    216. Terkeltaub R, Esdaile JM, Bruneau C, Danoff D, Watters AK. Vasculitis as a presenting manifestation of primary biliary cirrhosis: a case report. Clin Exp Rheumatol. 1984 Jan-Mar; 2(1):67-73. PMID: 6532613.
      View in: PubMed
    217. Terkeltaub R, Ginsberg MH. Molecular mechanisms of gouty arthritis: new insights into an old disease. Surv Synth Pathol Res. 1984; 3(5):386-96. PMID: 6395263.
      View in: PubMed
    218. Terkeltaub R, Tenner AJ, Kozin F, Ginsberg MH. Plasma protein binding by monosodium urate crystals. Analysis by two-dimensional gel electrophoresis. Arthritis Rheum. 1983 Jun; 26(6):775-83. PMID: 6305372.
      View in: PubMed
    219. Terkeltaub R, Esdaile J, Décary F, Tannenbaum H. A clinical study of older age rheumatoid arthritis with comparison to a younger onset group. J Rheumatol. 1983 Jun; 10(3):418-24. PMID: 6411919.
      View in: PubMed
    220. Terkeltaub R, Esdaile JM, Décary F, Harth M, Lister J, Lapointe N. HLA-Bw35 and prognosis in adult Still's disease. Arthritis Rheum. 1981 Dec; 24(12):1469-72. PMID: 6976785.
      View in: PubMed
    221. Esdaile JM, Rosenthall L, Terkeltaub R, Kloiber R. Prospective evaluation of sacroiliac scintigraphy in chronic inflammatory back pain. Arthritis Rheum. 1980 Sep; 23(9):998-1003. PMID: 7417363.
      View in: PubMed
    Robert's Networks
    Concepts
    Derived automatically from this person's publications.
    See all (792) concept(s)
    _
    Co-Authors
    People in Profiles who have published with this person.
    See all (32) people
    _
    Similar People
    People who share similar concepts with this person.
    See all (59) people
    _
    Same Department
    Search Department
    ↑