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    Gavin Hamilton

    TitleProject Scientist
    SchoolUniversity of California, San Diego
    DepartmentRadiology
    Address9500 Gilman Drive #0888
    CA La Jolla 92093
    Phone858-246-2194
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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Yokoo T, Serai SD, Pirasteh A, Bashir MR, Hamilton G, Hernando D, Hu HH, Hetterich H, Kühn JP, Kukuk GM, Loomba R, Middleton MS, Obuchowski NA, Song JS, Tang A, Wu X, Reeder SB, Sirlin CB. Linearity, Bias, and Precision of Hepatic Proton Density Fat Fraction Measurements by Using MR Imaging: A Meta-Analysis. Radiology. 2017 Sep 11; 170550. PMID: 28892458.
        View in: PubMed
      2. Hong CW, Wolfson T, Sy EZ, Schlein AN, Hooker JC, Fazeli Dehkordy S, Hamilton G, Reeder SB, Loomba R, Sirlin CB. Optimization of region-of-interest sampling strategies for hepatic MRI proton density fat fraction quantification. J Magn Reson Imaging. 2017 Aug 26. PMID: 28842937.
        View in: PubMed
      3. Hamilton G, Wheeler K, Di Michele J, Lalu MM, McIsaac DI. A Systematic Review and Meta-analysis Examining the Impact of Incident Postoperative Delirium on Mortality. Anesthesiology. 2017 Jul; 127(1):78-88. PMID: 28459734.
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      4. Wang K, Manning P, Szeverenyi N, Wolfson T, Hamilton G, Middleton MS, Vaida F, Yin M, Glaser K, Ehman RL, Sirlin CB. Repeatability and reproducibility of 2D and 3D hepatic MR elastography with rigid and flexible drivers at end-expiration and end-inspiration in healthy volunteers. Abdom Radiol (NY). 2017 Jun 13. PMID: 28612163.
        View in: PubMed
      5. Mamidipalli A, Hamilton G, Manning P, Hong CW, Park CC, Wolfson T, Hooker J, Heba E, Schlein A, Gamst A, Durelle J, Paiz M, Middleton MS, Schwimmer JB, Sirlin CB. Cross-sectional correlation between hepatic R2* and proton density fat fraction (PDFF) in children with hepatic steatosis. J Magn Reson Imaging. 2017 May 25. PMID: 28543915.
        View in: PubMed
      6. Schwimmer JB, Behling C, Angeles JE, Paiz M, Durelle J, Africa J, Newton KP, Brunt EM, Lavine JE, Abrams SH, Masand P, Krishnamurthy R, Wong K, Ehman RL, Yin M, Glaser KJ, Dzyubak B, Wolfson T, Gamst AC, Hooker J, Haufe W, Schlein A, Hamilton G, Middleton MS, Sirlin CB. Magnetic Resonance Elastography Measured Shear Stiffness as a Biomarker of Fibrosis in Pediatric Nonalcoholic Fatty Liver Disease. Hepatology. 2017 May 11. PMID: 28493388.
        View in: PubMed
      7. Haufe WM, Wolfson T, Hooker CA, Hooker JC, Covarrubias Y, Schlein AN, Hamilton G, Middleton MS, Angeles JE, Hernando D, Reeder SB, Schwimmer JB, Sirlin CB. Accuracy of PDFF estimation by magnitude-based and complex-based MRI in children with MR spectroscopy as a reference. J Magn Reson Imaging. 2017 Mar 21. PMID: 28323377.
        View in: PubMed
      8. Middleton MS, Haufe W, Hooker J, Borga M, Dahlqvist Leinhard O, Romu T, Tunón P, Hamilton G, Wolfson T, Gamst A, Loomba R, Sirlin CB. Quantifying Abdominal Adipose Tissue and Thigh Muscle Volume and Hepatic Proton Density Fat Fraction: Repeatability and Accuracy of an MR Imaging-based, Semiautomated Analysis Method. Radiology. 2017 May; 283(2):438-449. PMID: 28278002.
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      9. Yu NY, Wolfson T, Middleton MS, Hamilton G, Gamst A, Angeles JE, Schwimmer JB, Sirlin CB. Bone marrow fat content is correlated with hepatic fat content in paediatric non-alcoholic fatty liver disease. Clin Radiol. 2017 Jan 04. PMID: 28063601.
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      10. Park CC, Hamilton G, Desai A, Zand KA, Wolfson T, Hooker JC, Costa E, Heba E, Clark L, Gamst A, Loomba R, Middleton MS, Sirlin CB. Effect of intravenous gadoxetate disodium and flip angle on hepatic proton density fat fraction estimation with six-echo, gradient-recalled-echo, magnitude-based MR imaging at 3T. Abdom Radiol (NY). 2016 Dec 28. PMID: 28028556.
        View in: PubMed
      11. Manning PM, Hamilton G, Wang K, Park C, Hooker JC, Wolfson T, Gamst A, Haufe WM, Schlein AN, Middleton MS, Sirlin CB. Agreement between region-of-interest- and parametric map-based hepatic proton density fat fraction estimation in adults with chronic liver disease. Abdom Radiol (NY). 2016 Sep 29. PMID: 27688063.
        View in: PubMed
      12. Hamilton G, Schlein AN, Middleton MS, Hooker CA, Wolfson T, Gamst AC, Loomba R, Sirlin CB. In vivo triglyceride composition of abdominal adipose tissue measured by 1 H MRS at 3T. J Magn Reson Imaging. 2016 Aug 29. PMID: 27571403.
        View in: PubMed
      13. Hernando D, Sharma SD, Aliyari Ghasabeh M, Alvis BD, Arora SS, Hamilton G, Pan L, Shaffer JM, Sofue K, Szeverenyi NM, Welch EB, Yuan Q, Bashir MR, Kamel IR, Rice MJ, Sirlin CB, Yokoo T, Reeder SB. Multisite, multivendor validation of the accuracy and reproducibility of proton-density fat-fraction quantification at 1.5T and 3T using a fat-water phantom. Magn Reson Med. 2016 Apr 15. PMID: 27080068.
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      14. Tyagi A, Yeganeh O, Levin Y, Hooker JC, Hamilton G, Wolfson T, Gamst A, Zand AK, Heba E, Loomba R, Schwimmer J, Middleton MS, Sirlin CB. Intra- and inter-examination repeatability of magnetic resonance spectroscopy, magnitude-based MRI, and complex-based MRI for estimation of hepatic proton density fat fraction in overweight and obese children and adults. Abdom Imaging. 2015 Oct; 40(8):3070-7. PMID: 26350282.
        View in: PubMed
      15. Achmad E, Yokoo T, Hamilton G, Heba ER, Hooker JC, Changchien C, Schroeder M, Wolfson T, Gamst A, Schwimmer JB, Lavine JE, Sirlin CB, Middleton MS. Feasibility of and agreement between MR imaging and spectroscopic estimation of hepatic proton density fat fraction in children with known or suspected nonalcoholic fatty liver disease. Abdom Imaging. 2015 Oct; 40(8):3084-90. PMID: 26205992.
        View in: PubMed
      16. Heba ER, Desai A, Zand KA, Hamilton G, Wolfson T, Schlein AN, Gamst A, Loomba R, Sirlin CB, Middleton MS. Accuracy and the effect of possible subject-based confounders of magnitude-based MRI for estimating hepatic proton density fat fraction in adults, using MR spectroscopy as reference. J Magn Reson Imaging. 2016 Feb; 43(2):398-406. PMID: 26201284.
        View in: PubMed
      17. Hamilton G, Middleton MS, Hooker JC, Haufe WM, Forbang NI, Allison MA, Loomba R, Sirlin CB. In vivo breath-hold (1) H MRS simultaneous estimation of liver proton density fat fraction, and T1 and T2 of water and fat, with a multi-TR, multi-TE sequence. J Magn Reson Imaging. 2015 Dec; 42(6):1538-43. PMID: 26114603.
        View in: PubMed
      18. Zand KA, Shah A, Heba E, Wolfson T, Hamilton G, Lam J, Chen J, Hooker JC, Gamst AC, Middleton MS, Schwimmer JB, Sirlin CB. Accuracy of multiecho magnitude-based MRI (M-MRI) for estimation of hepatic proton density fat fraction (PDFF) in children. J Magn Reson Imaging. 2015 Nov; 42(5):1223-32. PMID: 25847512.
        View in: PubMed
      19. Schwimmer JB, Middleton MS, Behling C, Newton KP, Awai HI, Paiz MN, Lam J, Hooker JC, Hamilton G, Fontanesi J, Sirlin CB. Magnetic resonance imaging and liver histology as biomarkers of hepatic steatosis in children with nonalcoholic fatty liver disease. Hepatology. 2015 Jun; 61(6):1887-95. PMID: 25529941.
        View in: PubMed
      20. Artz NS, Haufe WM, Hooker CA, Hamilton G, Wolfson T, Campos GM, Gamst AC, Schwimmer JB, Sirlin CB, Reeder SB. Reproducibility of MR-based liver fat quantification across field strength: Same-day comparison between 1.5T and 3T in obese subjects. J Magn Reson Imaging. 2015 Sep; 42(3):811-7. PMID: 25620624.
        View in: PubMed
      21. Tang A, Chen J, Le TA, Changchien C, Hamilton G, Middleton MS, Loomba R, Sirlin CB. Cross-sectional and longitudinal evaluation of liver volume and total liver fat burden in adults with nonalcoholic steatohepatitis. Abdom Imaging. 2015 Jan; 40(1):26-37. PMID: 25015398.
        View in: PubMed
      22. Tang A, Desai A, Hamilton G, Wolfson T, Gamst A, Lam J, Clark L, Hooker J, Chavez T, Ang BD, Middleton MS, Peterson M, Loomba R, Sirlin CB. Accuracy of MR Imaging-estimated Proton Density Fat Fraction for Classification of Dichotomized Histologic Steatosis Grades in Nonalcoholic Fatty Liver Disease. Radiology. 2015 Feb; 274(2):416-25. PMID: 25247408.
        View in: PubMed
      23. Valayannopoulos V, Malinova V, Honzík T, Balwani M, Breen C, Deegan PB, Enns GM, Jones SA, Kane JP, Stock EO, Tripuraneni R, Eckert S, Schneider E, Hamilton G, Middleton MS, Sirlin C, Kessler B, Bourdon C, Boyadjiev SA, Sharma R, Twelves C, Whitley CB, Quinn AG. Sebelipase alfa over 52weeks reduces serum transaminases, liver volume and improves serum lipids in patients with lysosomal acid lipase deficiency. J Hepatol. 2014 Nov; 61(5):1135-42. PMID: 24993530.
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      24. Koslik HJ, Hamilton G, Golomb BA. Mitochondrial Dysfunction in Gulf War Illness Revealed by 31Phosphorus Magnetic Resonance Spectroscopy: A Case-Control Study. PLoS One. 2014; 9(3):e92887. PMID: 24675771.
        View in: PubMed
      25. Hamilton G, Fish J. Pediatric toxic epidermal necrolysis: an institutional review of patients admitted to an intensive care unit. J Burn Care Res. 2013 Nov-Dec; 34(6):e351-8. PMID: 23816996.
        View in: PubMed
      26. Golomb BA, Erickson LC, Zeeland AA, Koperski S, Haas RH, Wallace DC, Naviaux RK, Lincoln AJ, Reiner GE, Hamilton G. Assessing Bioenergetic Compromise in Autism Spectrum Disorder With 31P Magnetic Resonance Spectroscopy: Preliminary Report. J Child Neurol. 2014 Feb; 29(2):187-93. PMID: 24141271.
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      27. Noureddin M, Lam J, Peterson MR, Middleton M, Hamilton G, Le TA, Bettencourt R, Changchien C, Brenner DA, Sirlin C, Loomba R. Utility of magnetic resonance imaging versus histology for quantifying changes in liver fat in nonalcoholic fatty liver disease trials. Hepatology. 2013 Dec; 58(6):1930-40. PMID: 23696515.
        View in: PubMed
      28. Negrete LM, Middleton MS, Clark L, Wolfson T, Gamst AC, Lam J, Changchien C, Deyoung-Dominguez IM, Hamilton G, Loomba R, Schwimmer J, Sirlin CB. Inter-examination precision of magnitude-based MRI for estimation of segmental hepatic proton density fat fraction in obese subjects. J Magn Reson Imaging. 2014 May; 39(5):1265-71. PMID: 24136736.
        View in: PubMed
      29. Levin YS, Yokoo T, Wolfson T, Gamst AC, Collins J, Achmad EA, Hamilton G, Middleton MS, Loomba R, Sirlin CB. Effect of echo-sampling strategy on the accuracy of out-of-phase and in-phase multiecho gradient-Echo MRI hepatic fat fraction estimation. J Magn Reson Imaging. 2014 Mar; 39(3):567-75. PMID: 23720420.
        View in: PubMed
      30. Johnson BL, Schroeder ME, Wolfson T, Gamst AC, Hamilton G, Shiehmorteza M, Loomba R, Schwimmer JB, Reeder S, Middleton MS, Sirlin CB. Effect of flip angle on the accuracy and repeatability of hepatic proton density fat fraction estimation by complex data-based, T1-independent, T2*-corrected, spectrum-modeled MRI. J Magn Reson Imaging. 2014 Feb; 39(2):440-7. PMID: 23596052.
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      31. Tang A, Tan J, Sun M, Hamilton G, Bydder M, Wolfson T, Gamst AC, Middleton M, Brunt EM, Loomba R, Lavine JE, Schwimmer JB, Sirlin CB. Nonalcoholic fatty liver disease: MR imaging of liver proton density fat fraction to assess hepatic steatosis. Radiology. 2013 May; 267(2):422-31. PMID: 23382291.
        View in: PubMed
      32. Erickson LC, Scott-Van Zeeland AA, Hamilton G, Lincoln A, Golomb BA. Brief report: approaches to 31P-MRS in awake, non-sedated children with and without autism spectrum disorder. J Autism Dev Disord. 2012 Jun; 42(6):1120-6. PMID: 21979108.
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      33. Hansen KH, Schroeder ME, Hamilton G, Sirlin CB, Bydder M. Robustness of fat quantification using chemical shift imaging. Magn Reson Imaging. 2012 Feb; 30(2):151-7. PMID: 22055856.
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      34. Reeder SB, Cruite I, Hamilton G, Sirlin CB. Quantitative assessment of liver fat with magnetic resonance imaging and spectroscopy. J Magn Reson Imaging. 2011 Oct; 34(4):729-49. PMID: 21928307.
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      35. Reeder SB, Cruite I, Hamilton G, Sirlin CB. Quantitative Assessment of Liver Fat with Magnetic Resonance Imaging and Spectroscopy. J Magn Reson Imaging. 2011 Oct; 34(4):spcone. PMID: 22025886.
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      36. Bydder M, Girard O, Hamilton G. Mapping the double bonds in triglycerides. Magn Reson Imaging. 2011 Oct; 29(8):1041-6. PMID: 21868182.
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      37. Hamilton G, Smith DL, Bydder M, Nayak KS, Hu HH. MR properties of brown and white adipose tissues. J Magn Reson Imaging. 2011 Aug; 34(2):468-73. PMID: 21780237.
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      38. Kang GH, Cruite I, Shiehmorteza M, Wolfson T, Gamst AC, Hamilton G, Bydder M, Middleton MS, Sirlin CB. Reproducibility of MRI-determined proton density fat fraction across two different MR scanner platforms. J Magn Reson Imaging. 2011 Oct; 34(4):928-34. PMID: 21769986.
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      39. Hines CD, Frydrychowicz A, Hamilton G, Tudorascu DL, Vigen KK, Yu H, McKenzie CA, Sirlin CB, Brittain JH, Reeder SB. T(1) independent, T(2) (*) corrected chemical shift based fat-water separation with multi-peak fat spectral modeling is an accurate and precise measure of hepatic steatosis. J Magn Reson Imaging. 2011 Apr; 33(4):873-81. PMID: 21448952.
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      40. Yu H, Shimakawa A, Hines CD, McKenzie CA, Hamilton G, Sirlin CB, Brittain JH, Reeder SB. Combination of complex-based and magnitude-based multiecho water-fat separation for accurate quantification of fat-fraction. Magn Reson Med. 2011 Jul; 66(1):199-206. PMID: 21695724.
        View in: PubMed
      41. Hamilton G, Meeuwisse WH, Emery CA, Steele RJ, Shrier I. Past injury as a risk factor: an illustrative example where appearances are deceiving. Am J Epidemiol. 2011 Apr 15; 173(8):941-8. PMID: 21343249.
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      42. Meisamy S, Hines CD, Hamilton G, Sirlin CB, McKenzie CA, Yu H, Brittain JH, Reeder SB. Quantification of hepatic steatosis with T1-independent, T2-corrected MR imaging with spectral modeling of fat: blinded comparison with MR spectroscopy. Radiology. 2011 Mar; 258(3):767-75. PMID: 21248233.
        View in: PubMed
      43. Yokoo T, Shiehmorteza M, Hamilton G, Wolfson T, Schroeder ME, Middleton MS, Bydder M, Gamst AC, Kono Y, Kuo A, Patton HM, Horgan S, Lavine JE, Schwimmer JB, Sirlin CB. Estimation of hepatic proton-density fat fraction by using MR imaging at 3.0 T. Radiology. 2011 Mar; 258(3):749-59. PMID: 21212366.
        View in: PubMed
      44. Hamilton G, Yokoo T, Bydder M, Cruite I, Schroeder ME, Sirlin CB, Middleton MS. In vivo characterization of the liver fat ¹H MR spectrum. NMR Biomed. 2011 Aug; 24(7):784-90. PMID: 21834002.
        View in: PubMed
      45. Yokoo T, Bae WC, Hamilton G, Karimi A, Borgstede JP, Bowen BC, Sirlin CB, Chung CB, Crues JV, Bradley WG, Bydder GM. A quantitative approach to sequence and image weighting. J Comput Assist Tomogr. 2010 May-Jun; 34(3):317-31. PMID: 20498530.
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      46. Hamilton G, Middleton MS, Bydder M, Yokoo T, Schwimmer JB, Kono Y, Patton HM, Lavine JE, Sirlin CB. Effect of PRESS and STEAM sequences on magnetic resonance spectroscopic liver fat quantification. J Magn Reson Imaging. 2009 Jul; 30(1):145-52. PMID: 19557733.
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      47. Yokoo T, Bydder M, Hamilton G, Middleton MS, Gamst AC, Wolfson T, Hassanein T, Patton HM, Lavine JE, Schwimmer JB, Sirlin CB. Nonalcoholic fatty liver disease: diagnostic and fat-grading accuracy of low-flip-angle multiecho gradient-recalled-echo MR imaging at 1.5 T. Radiology. 2009 Apr; 251(1):67-76. PMID: 19221054.
        View in: PubMed
      48. Cassidy FH, Yokoo T, Aganovic L, Hanna RF, Bydder M, Middleton MS, Hamilton G, Chavez AD, Schwimmer JB, Sirlin CB. Fatty liver disease: MR imaging techniques for the detection and quantification of liver steatosis. Radiographics. 2009 Jan-Feb; 29(1):231-60. PMID: 19168847.
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      49. Bydder M, Hamilton G, Yokoo T, Sirlin CB. Optimal phased-array combination for spectroscopy. Magn Reson Imaging. 2008 Jul; 26(6):847-50. PMID: 18486392.
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      50. Forton DM, Hamilton G, Allsop JM, Grover VP, Wesnes K, O'Sullivan C, Thomas HC, Taylor-Robinson SD. Cerebral immune activation in chronic hepatitis C infection: a magnetic resonance spectroscopy study. J Hepatol. 2008 Sep; 49(3):316-22. PMID: 18538439.
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      51. Puri BK, Counsell SJ, Ross BM, Hamilton G, Bustos MG, Treasaden IH. Evidence from in vivo 31-phosphorus magnetic resonance spectroscopy phosphodiesters that exhaled ethane is a biomarker of cerebral n-3 polyunsaturated fatty acid peroxidation in humans. BMC Psychiatry. 2008 Apr 17; 8 Suppl 1:S2. PMID: 18433512; PMCID: PMC2330077.
        View in: PubMed, PubMed Central
      52. Bydder M, Yokoo T, Hamilton G, Middleton MS, Chavez AD, Schwimmer JB, Lavine JE, Sirlin CB. Relaxation effects in the quantification of fat using gradient echo imaging. Magn Reson Imaging. 2008 Apr; 26(3):347-59. PMID: 18093781.
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      53. Puri BK, Counsell SJ, Hamilton G, Bustos MG, Treasaden IH. Brain cell membrane motion-restricted phospholipids in patients with schizophrenia who have seriously and dangerously violently offended. Prog Neuropsychopharmacol Biol Psychiatry. 2008 Apr 1; 32(3):751-4. PMID: 18164794.
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      54. Du J, Hamilton G, Takahashi A, Bydder M, Chung CB. Ultrashort echo time spectroscopic imaging (UTESI) of cortical bone. Magn Reson Med. 2007 Nov; 58(5):1001-9. PMID: 17969110.
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      55. Lim AK, Patel N, Hamilton G, Mylvahan K, Kuo YT, Goldin RD, Taylor-Robinson SD. 31P MR spectroscopy in assessment of response to antiviral therapy for hepatitis C virus-related liver disease. AJR Am J Roentgenol. 2007 Oct; 189(4):819-23. PMID: 17885051.
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      56. Chung YL, Alexanderson H, Pipitone N, Morrison C, Dastmalchi M, Ståhl-Hallengren C, Richards S, Thomas EL, Hamilton G, Bell JD, Lundberg IE, Scott DL. Creatine supplements in patients with idiopathic inflammatory myopathies who are clinically weak after conventional pharmacologic treatment: Six-month, double-blind, randomized, placebo-controlled trial. Arthritis Rheum. 2007 May 15; 57(4):694-702. PMID: 17471547.
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      57. Thomas EL, Brynes AE, Hamilton G, Patel N, Spong A, Goldin RD, Frost G, Bell JD, Taylor-Robinson SD. Effect of nutritional counselling on hepatic, muscle and adipose tissue fat content and distribution in non-alcoholic fatty liver disease. World J Gastroenterol. 2006 Sep 28; 12(36):5813-9. PMID: 17007047.
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      58. Hamilton G, Allsop JM, Patel N, Forton DM, Thomas HC, O'Sullivan CP, Hajnal JV, Taylor-Robinson SD. Variations due to analysis technique in intracellular pH measurements in simulated and in vivo 31P MR spectra of the human brain. J Magn Reson Imaging. 2006 Apr; 23(4):459-64. PMID: 16506142.
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      59. Khan SA, Cox IJ, Hamilton G, Thomas HC, Taylor-Robinson SD. In vivo and in vitro nuclear magnetic resonance spectroscopy as a tool for investigating hepatobiliary disease: a review of H and P MRS applications. Liver Int. 2005 Apr; 25(2):273-81. PMID: 15780050.
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      60. Ostberg JE, Thomas EL, Hamilton G, Attar MJ, Bell JD, Conway GS. Excess visceral and hepatic adipose tissue in Turner syndrome determined by magnetic resonance imaging: estrogen deficiency associated with hepatic adipose content. J Clin Endocrinol Metab. 2005 May; 90(5):2631-5. PMID: 15713713.
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      61. Holdcroft A, Hall L, Hamilton G, Counsell SJ, Bydder GM, Bell JD. Phosphorus-31 brain MR spectroscopy in women during and after pregnancy compared with nonpregnant control subjects. AJNR Am J Neuroradiol. 2005 Feb; 26(2):352-6. PMID: 15709134.
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      62. Gatehouse PD, Thomas RW, Robson MD, Hamilton G, Herlihy AH, Bydder GM. Magnetic resonance imaging of the knee with ultrashort TE pulse sequences. Magn Reson Imaging. 2004 Oct; 22(8):1061-7. PMID: 15527992.
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      63. Hamilton G, Patel N, Forton DM, Hajnal JV, Taylor-Robinson SD. Prior knowledge for time domain quantification of in vivo brain or liver 31P MR spectra. NMR Biomed. 2003 May; 16(3):168-76. PMID: 12884361.
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      64. Lim AK, Patel N, Hamilton G, Hajnal JV, Goldin RD, Taylor-Robinson SD. The relationship of in vivo 31P MR spectroscopy to histology in chronic hepatitis C. Hepatology. 2003 Apr; 37(4):788-94. PMID: 12668971.
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      65. Lim AK, Hamilton G, Patel N, Bell JD, Taylor-Robinson SD. H MR spectroscopy in the evaluation of the severity of chronic liver disease. Radiology. 2003 Jan; 226(1):288-9. PMID: 12511705.
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