Won Bae

TitleAssociate Adjunct Professor
InstitutionUniversity of California San Diego
Address9500 Gilman Drive #0997
La Jolla CA 92093
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    Collapse Biography 
    Collapse Education and Training
    University of California San DiegoPost-docRadiology
    University of California San DiegoPh.D.Bioengineering

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Ultrashort Time to Echo MRI of Disco Vertebral Junction
    NIH/NIAMS R01AR066622Apr 1, 2015 - Jan 31, 2020
    Role: Principal Investigator
    UTE MR Imaging of the Cartilaginous Endplate in the Lumbar Spine
    NIH/NIAMS K01AR059764Jul 1, 2010 - Jun 30, 2014
    Role: Principal Investigator
    Biomechanical Basis for Treatment of Cartilage defects
    NIH/NIAMS F32AR054248Sep 1, 2006 - Aug 31, 2008
    Role: Principal Investigator

    Collapse ORNG Applications 
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Miyazaki S, Diwan AD, Kato K, Cheng K, Bae W, Sun Y, Yamada J, Muehleman C, Lenz ME, Inoue N, Sah RL, Kawakami M, Masuda K. ISSLS PRIZE IN BASIC SCIENCE 2018: Growth differentiation factor-6 attenuated pro-inflammatory molecular changes in the rabbit anular-puncture model and degenerated disc-induced pain generation in the rat xenograft radiculopathy model. Eur Spine J. 2018 Apr; 27(4):739-751. PMID: 29460012.
      View in: PubMed
    2. Akeda K, Ohishi K, Masuda K, Bae W, Takegami N, Yamada J, Nakamura T, Sakakibara T, Kasai Y, Sudo A. Intradiscal Injection of Autologous Platelet-Rich Plasma Releasate to Treat Discogenic Low Back Pain: A Preliminary Clinical Trial. Asian Spine J. 2017 Jun; 11(3):380-389. PMID: 28670405.
      View in: PubMed
    3. Siriwanarangsun P, Bae W, Statum S, Chung CB. Advanced MRI Techniques for the Ankle. AJR Am J Roentgenol. 2017 Sep; 209(3):511-524. PMID: 28570096.
      View in: PubMed
    4. Ariyachaipanich A, Bae W, Statum S, Chung CB. Update on MRI Pulse Sequences for the Knee: Imaging of Cartilage, Meniscus, Tendon, and Hardware. Semin Musculoskelet Radiol. 2017 Apr; 21(2):45-62. PMID: 28355670.
      View in: PubMed
    5. Bae W, Ruangchaijatuporn T, Chung CB. New Techniques in MR Imaging of the Ankle and Foot. Magn Reson Imaging Clin N Am. 2017 Feb; 25(1):211-225. PMID: 27888849.
      View in: PubMed
    6. Siriwanarangsun P, Statum S, Biswas R, Bae W, Chung CB. Ultrashort time to echo magnetic resonance techniques for the musculoskeletal system. Quant Imaging Med Surg. 2016 Dec; 6(6):731-743. PMID: 28090449.
      View in: PubMed
    7. Hwang D, Kim S, Abeydeera NA, Statum S, Masuda K, Chung CB, Siriwanarangsun P, Bae W. Quantitative magnetic resonance imaging of the lumbar intervertebral discs. Quant Imaging Med Surg. 2016 Dec; 6(6):744-755. PMID: 28090450.
      View in: PubMed
    8. Chen KC, Tran B, Biswas R, Statum S, Masuda K, Chung CB, Bae W. Evaluation of the disco-vertebral junction using ultrashort time-to-echo magnetic resonance imaging: inter-reader agreement and association with vertebral endplate lesions. Skeletal Radiol. 2016 Sep; 45(9):1249-56. PMID: 27241121; PMCID: PMC4947562 [Available on 09/01/17].
    9. Choi JY, Biswas R, Bae W, Healey R, Im M, Statum S, Chang EY, Du J, Bydder GM, D'Lima D, Chung CB. Thickness of the Meniscal Lamellar Layer: Correlation with Indentation Stiffness and Comparison of Normal and Abnormally Thick Layers by Using Multiparametric Ultrashort Echo Time MR Imaging. Radiology. 2016 07; 280(1):161-8. PMID: 26829523; PMCID: PMC4942992 [Available on 07/01/17].
    10. Bae W, Ruangchaijatuporn T, Chang EY, Biswas R, Du J, Statum S, Chung CB. MR morphology of triangular fibrocartilage complex: correlation with quantitative MR and biomechanical properties. Skeletal Radiol. 2016 Apr; 45(4):447-54. PMID: 26691643; PMCID: PMC4755783 [Available on 04/01/17].
    11. Bae W, Tafur M, Chang EY, Du J, Biswas R, Kwack KS, Healey R, Statum S, Chung CB. High-resolution morphologic and ultrashort time-to-echo quantitative magnetic resonance imaging of the temporomandibular joint. Skeletal Radiol. 2016 Mar; 45(3):383-91. PMID: 26685898; PMCID: PMC4720153 [Available on 03/01/17].
    12. Chang EY, Du J, Bae W, Chung CB. Qualitative and Quantitative Ultrashort Echo Time Imaging of Musculoskeletal Tissues. Semin Musculoskelet Radiol. 2015 Sep; 19(4):375-86. PMID: 26583365.
      View in: PubMed
    13. Iwasaki K, Tafur M, Chang EY, Statum S, Biswas R, Tran B, Bae W, Du J, Bydder GM, Chung CB. High-Resolution Qualitative and Quantitative Magnetic Resonance Evaluation of the Glenoid Labrum. J Comput Assist Tomogr. 2015 Nov-Dec; 39(6):936-44. PMID: 26359581; PMCID: PMC4644441 [Available on 11/01/16].
    14. Chang EY, Campos JC, Bae W, Znamirowski R, Statum S, Du J, Chung CB. Ultrashort Echo Time T1? Is Sensitive to Enzymatic Degeneration of Human Menisci. J Comput Assist Tomogr. 2015 Sep-Oct; 39(5):637-42. PMID: 25992688; PMCID: PMC4575241.
    15. Chang EY, Bae W, Shao H, Biswas R, Li S, Chen J, Patil S, Healey R, D'Lima DD, Chung CB, Du J. Ultrashort echo time magnetization transfer (UTE-MT) imaging of cortical bone. NMR Biomed. 2015 Jul; 28(7):873-80. PMID: 25981914; PMCID: PMC4652942.
    16. Chang EY, Du J, Biswas R, Statum S, Pauli C, Bae W, Chung CB. Off-resonance saturation ratio obtained with ultrashort echo time-magnetization transfer techniques is sensitive to changes in static tensile loading of tendons and degeneration. J Magn Reson Imaging. 2015 Oct; 42(4):1064-71. PMID: 25808266.
      View in: PubMed
    17. Yamaguchi T, Goto S, Nishigaki Y, Espinoza Orías AA, Bae W, Masuda K, Inoue N. Microstructural analysis of three-dimensional canal network in the rabbit lumbar vertebral endplate. J Orthop Res. 2015 Feb; 33(2):270-6. PMID: 25367593.
      View in: PubMed
    18. Chang EY, Du J, Iwasaki K, Biswas R, Statum S, He Q, Bae W, Chung CB. Single- and Bi-component T2* analysis of tendon before and during tensile loading, using UTE sequences. J Magn Reson Imaging. 2015 Jul; 42(1):114-20. PMID: 25223714.
      View in: PubMed
    19. Chang EY, Bae W, Chung CB. Imaging the knee in the setting of metal hardware. Magn Reson Imaging Clin N Am. 2014 Nov; 22(4):765-86. PMID: 25442032.
      View in: PubMed
    20. Bae W, Patil S, Biswas R, Li S, Chang EY, Statum S, D'Lima DD, Chung CB, Du J. Magnetic resonance imaging assessed cortical porosity is highly correlated with µCT porosity. Bone. 2014 Sep; 66:56-61. PMID: 24928498; PMCID: PMC4125420.
    21. Bae W, Biswas R, Statum S, Sah RL, Chung CB. Sensitivity of quantitative UTE MRI to the biomechanical property of the temporomandibular joint disc. Skeletal Radiol. 2014 Sep; 43(9):1217-23. PMID: 24878837; PMCID: PMC4349555.
    22. Gregory DE, Bae W, Sah RL, Masuda K. Disc degeneration reduces the delamination strength of the annulus fibrosus in the rabbit annular disc puncture model. Spine J. 2014 Jul 01; 14(7):1265-71. PMID: 24594442; PMCID: PMC4063999.
    23. Li S, Chang EY, Bae W, Chung CB, Gao S, Bao S, Bydder GM, Hua Y, Du J. Ultrashort echo time bi-component analysis of cortical bone--a field dependence study. Magn Reson Med. 2014 Mar; 71(3):1075-81. PMID: 23630048.
      View in: PubMed
    24. Li S, Chang EY, Bae W, Chung CB, Hua Y, Zhou Y, Du J. The effect of excitation and preparation pulses on nonslice selective 2D UTE bicomponent analysis of bound and free water in cortical bone at 3T. Med Phys. 2014 Feb; 41(2):022306. PMID: 24506644; PMCID: PMC3987690.
    25. Bae W, Biswas R, Chen K, Chang EY, Chung CB. UTE MRI of the Osteochondral Junction. Curr Radiol Rep. 2014 Feb 01; 2(2):35. PMID: 25061547.
      View in: PubMed
    26. Yamaguchi T, Inoue N, Sah RL, Lee YP, Taborek AP, Williams GM, Moseley TA, Bae W, Masuda K. Micro-computed tomography-based three-dimensional kinematic analysis during lateral bending for spinal fusion assessment in a rat posterolateral lumbar fusion model. Tissue Eng Part C Methods. 2014 Jul; 20(7):578-87. PMID: 24199634; PMCID: PMC4074752.
    27. Chang EY, Pallante-Kichura AL, Bae W, Du J, Statum S, Wolfson T, Gamst AC, Cory E, Amiel D, Bugbee WD, Sah RL, Chung CB. Development of a Comprehensive Osteochondral Allograft MRI Scoring System (OCAMRISS) with Histopathologic, Micro-Computed Tomography, and Biomechanical Validation. Cartilage. 2014 Jan 01; 5(1):16-27. PMID: 24489999.
      View in: PubMed
    28. Chang EY, Bae W, Statum S, Du J, Chung CB. Effects of repetitive freeze-thawing cycles on T2 and T2 of the Achilles tendon. Eur J Radiol. 2014 Feb; 83(2):349-53. PMID: 24239237.
      View in: PubMed
    29. Chang EY, Du J, Bae W, Statum S, Chung CB. Effects of Achilles tendon immersion in saline and perfluorochemicals on T2 and T2*. J Magn Reson Imaging. 2014 Aug; 40(2):496-500. PMID: 24155129.
      View in: PubMed
    30. Geiger D, Bae W, Statum S, Du J, Chung CB. Quantitative 3D ultrashort time-to-echo (UTE) MRI and micro-CT (µCT) evaluation of the temporomandibular joint (TMJ) condylar morphology. Skeletal Radiol. 2014 Jan; 43(1):19-25. PMID: 24092237; PMCID: PMC4000774.
    31. Chang EY, Lim WY, Wolfson T, Gamst AC, Chung CB, Bae W, Resnick DL. Frequency of atlantoaxial calcium pyrophosphate dihydrate deposition at CT. Radiology. 2013 Nov; 269(2):519-24. PMID: 23737539.
      View in: PubMed
    32. Patil S, Steklov N, Song L, Bae W, D'Lima DD. Comparative biomechanical analysis of human and caprine knee articular cartilage. Knee. 2014 Jan; 21(1):119-25. PMID: 23583005.
      View in: PubMed
    33. Bae W, Statum S, Zhang Z, Yamaguchi T, Wolfson T, Gamst AC, Du J, Bydder GM, Masuda K, Chung CB. Morphology of the cartilaginous endplates in human intervertebral disks with ultrashort echo time MR imaging. Radiology. 2013 Feb; 266(2):564-74. PMID: 23192776; PMCID: PMC3558871.
    34. Omoumi P, Bae W, Du J, Diaz E, Statum S, Bydder GM, Chung CB. Meniscal calcifications: morphologic and quantitative evaluation by using 2D inversion-recovery ultrashort echo time and 3D ultrashort echo time 3.0-T MR imaging techniques--feasibility study. Radiology. 2012 Jul; 264(1):260-8. PMID: 22723564; PMCID: PMC3380410.
    35. Pauli C, Bae W, Lee M, Lotz M, Bydder GM, D'Lima DL, Chung CB, Du J. Ultrashort-echo time MR imaging of the patella with bicomponent analysis: correlation with histopathologic and polarized light microscopic findings. Radiology. 2012 Aug; 264(2):484-93. PMID: 22653187; PMCID: PMC3401353.
    36. Gregory DE, Bae W, Sah RL, Masuda K. Anular delamination strength of human lumbar intervertebral disc. Eur Spine J. 2012 Sep; 21(9):1716-23. PMID: 22547212; PMCID: PMC3459123.
    37. Bae W, Chen PC, Chung CB, Masuda K, D'Lima D, Du J. Quantitative ultrashort echo time (UTE) MRI of human cortical bone: correlation with porosity and biomechanical properties. J Bone Miner Res. 2012 Apr; 27(4):848-57. PMID: 22190232; PMCID: PMC3463505.
    38. Biswas R, Bae W, Diaz E, Masuda K, Chung CB, Bydder GM, Du J. Ultrashort echo time (UTE) imaging with bi-component analysis: bound and free water evaluation of bovine cortical bone subject to sequential drying. Bone. 2012 Mar; 50(3):749-55. PMID: 22178540; PMCID: PMC3463503.
    39. Du J, Diaz E, Carl M, Bae W, Chung CB, Bydder GM. Ultrashort echo time imaging with bicomponent analysis. Magn Reson Med. 2012 Mar; 67(3):645-9. PMID: 22034242.
      View in: PubMed
    40. Bae W, Masuda K. Emerging technologies for molecular therapy for intervertebral disk degeneration. Orthop Clin North Am. 2011 Oct; 42(4):585-601, ix. PMID: 21944594; PMCID: PMC4029337.
    41. Diaz E, Chung CB, Bae W, Statum S, Znamirowski R, Bydder GM, Du J. Ultrashort echo time spectroscopic imaging (UTESI): an efficient method for quantifying bound and free water. NMR Biomed. 2012 Jan; 25(1):161-8. PMID: 21766381.
      View in: PubMed
    42. Kokabi N, Bae W, Diaz E, Chung CB, Bydder GM, Du J. Ultrashort TE MR imaging of bovine cortical bone: the effect of water loss on the T1 and T2* relaxation times. Magn Reson Med. 2011 Aug; 66(2):476-82. PMID: 21360749.
      View in: PubMed
    43. Buck FM, Bae W, Diaz E, Du J, Statum S, Han ET, Chung CB. Comparison of T1rho measurements in agarose phantoms and human patellar cartilage using 2D multislice spiral and 3D magnetization prepared partitioned k-space spoiled gradient-echo snapshot techniques at 3 T. AJR Am J Roentgenol. 2011 Feb; 196(2):W174-9. PMID: 21257859; PMCID: PMC4674086.
    44. Sanal HT, Bae W, Pauli C, Du J, Statum S, Znamirowski R, Sah RL, Chung CB. Magnetic resonance imaging of the temporomandibular joint disc: feasibility of novel quantitative magnetic resonance evaluation using histologic and biomechanical reference standards. J Orofac Pain. 2011; 25(4):345-53. PMID: 22247930; PMCID: PMC4048068.
    45. Bae W, Du J, Bydder GM, Chung CB. Conventional and ultrashort time-to-echo magnetic resonance imaging of articular cartilage, meniscus, and intervertebral disk. Top Magn Reson Imaging. 2010 Oct; 21(5):275-89. PMID: 22129641; PMCID: PMC3561677.
    46. Muehleman C, Margulis A, Bae W, Masuda K. Relationship between knee and ankle degeneration in a population of organ donors. BMC Med. 2010 Jul 28; 8:48. PMID: 20667091; PMCID: PMC2925325.
    47. Hwang J, Kyubwa EM, Bae W, Bugbee WD, Masuda K, Sah RL. In Vitro Calcification of Immature Bovine Articular Cartilage: Formation of a Functional Zone of Calcified Cartilage. Cartilage. 2010 Oct 01; 1(4):287-297. PMID: 22745850.
      View in: PubMed
    48. Yokoo T, Bae W, Hamilton G, Karimi A, Borgstede JP, Bowen BC, Sirlin CB, Chung CB, Crues JV, Bradley WG, Bydder GM. A quantitative approach to sequence and image weighting. J Comput Assist Tomogr. 2010 May-Jun; 34(3):317-31. PMID: 20498530.
      View in: PubMed
    49. Bae W, Dwek JR, Znamirowski R, Statum SM, Hermida JC, D'Lima DD, Sah RL, Du J, Chung CB. Ultrashort echo time MR imaging of osteochondral junction of the knee at 3 T: identification of anatomic structures contributing to signal intensity. Radiology. 2010 Mar; 254(3):837-45. PMID: 20177096; PMCID: PMC2826697.
    50. Du J, Takahashi AM, Bae W, Chung CB, Bydder GM. Dual inversion recovery, ultrashort echo time (DIR UTE) imaging: creating high contrast for short-T(2) species. Magn Reson Med. 2010 Feb; 63(2):447-55. PMID: 20099332.
      View in: PubMed
    51. Bae W, Payanal MM, Chen AC, Hsieh-Bonassera ND, Ballard BL, Lotz MK, Coutts RD, Bugbee WD, Sah RL. Topographic Patterns of Cartilage Lesions in Knee Osteoarthritis. Cartilage. 2010 Jan; 1(1):10-19. PMID: 20664706.
      View in: PubMed
    52. Pallante AL, Bae W, Chen AC, Görtz S, Bugbee WD, Sah RL. Chondrocyte viability is higher after prolonged storage at 37 degrees C than at 4 degrees C for osteochondral grafts. Am J Sports Med. 2009 Nov; 37 Suppl 1:24S-32S. PMID: 19861697; PMCID: PMC2858049.
    53. Williams GM, Chan EF, Temple-Wong MM, Bae W, Masuda K, Bugbee WD, Sah RL. Shape, loading, and motion in the bioengineering design, fabrication, and testing of personalized synovial joints. J Biomech. 2010 Jan 05; 43(1):156-65. PMID: 19815214; PMCID: PMC2813363.
    54. Gratz KR, Wong BL, Bae W, Sah RL. The effects of focal articular defects on cartilage contact mechanics. J Orthop Res. 2009 May; 27(5):584-92. PMID: 18979528; PMCID: PMC2862585.
    55. Hwang J, Bae W, Shieu W, Lewis CW, Bugbee WD, Sah RL. Increased hydraulic conductance of human articular cartilage and subchondral bone plate with progression of osteoarthritis. Arthritis Rheum. 2008 Dec; 58(12):3831-42. PMID: 19035476; PMCID: PMC2603273.
    56. Wong BL, Bae W, Gratz KR, Sah RL. Shear deformation kinematics during cartilage articulation: effect of lubrication, degeneration, and stress relaxation. Mol Cell Biomech. 2008 Sep; 5(3):197-206. PMID: 18751528; PMCID: PMC2847289.
    57. Wong BL, Bae W, Chun J, Gratz KR, Lotz M, Sah RL. Biomechanics of cartilage articulation: effects of lubrication and degeneration on shear deformation. Arthritis Rheum. 2008 Jul; 58(7):2065-74. PMID: 18576324.
      View in: PubMed
    58. Han EH, Bae W, Hsieh-Bonassera ND, Wong VW, Schumacher BL, Görtz S, Masuda K, Bugbee WD, Sah RL. Shaped, stratified, scaffold-free grafts for articular cartilage defects. Clin Orthop Relat Res. 2008 Aug; 466(8):1912-20. PMID: 18506565; PMCID: PMC2584257.
    59. Gratz KR, Wong BL, Bae W, Sah RL. The effects of focal articular defects on intra-tissue strains in the surrounding and opposing cartilage. Biorheology. 2008; 45(3-4):193-207. PMID: 18836224.
      View in: PubMed
    60. Jadin KD, Bae W, Schumacher BL, Sah RL. Three-dimensional (3-D) imaging of chondrocytes in articular cartilage: growth-associated changes in cell organization. Biomaterials. 2007 Jan; 28(2):230-9. PMID: 16999994; PMCID: PMC2464614.
    61. Borazjani BH, Chen AC, Bae W, Patil S, Sah RL, Firestein GS, Bugbee WD. Effect of impact on chondrocyte viability during insertion of human osteochondral grafts. J Bone Joint Surg Am. 2006 Sep; 88(9):1934-43. PMID: 16951108.
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    62. Klein TJ, Chaudhry M, Bae W, Sah RL. Depth-dependent biomechanical and biochemical properties of fetal, newborn, and tissue-engineered articular cartilage. J Biomech. 2007; 40(1):182-90. PMID: 16387310.
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    63. Lewis CW, Williamson AK, Chen AC, Bae W, Temple MM, Wong WV, Nugent GE, James SP, Wheeler DL, Sah RL, Kawcak CE. Evaluation of subchondral bone mineral density associated with articular cartilage structure and integrity in healthy equine joints with different functional demands. Am J Vet Res. 2005 Oct; 66(10):1823-9. PMID: 16273917.
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    64. Jadin KD, Wong BL, Bae W, Li KW, Williamson AK, Schumacher BL, Price JH, Sah RL. Depth-varying density and organization of chondrocytes in immature and mature bovine articular cartilage assessed by 3d imaging and analysis. J Histochem Cytochem. 2005 Sep; 53(9):1109-19. PMID: 15879579.
      View in: PubMed
    65. Bae W, Lewis CW, Levenston ME, Sah RL. Indentation testing of human articular cartilage: effects of probe tip geometry and indentation depth on intra-tissue strain. J Biomech. 2006; 39(6):1039-47. PMID: 16549094.
      View in: PubMed
    66. Nugent GE, Law AW, Wong EG, Temple MM, Bae W, Chen AC, Kawcak CE, Sah RL. Site- and exercise-related variation in structure and function of cartilage from equine distal metacarpal condyle. Osteoarthritis Cartilage. 2004 Oct; 12(10):826-33. PMID: 15450533.
      View in: PubMed
    67. Lane JG, Massie JB, Ball ST, Amiel ME, Chen AC, Bae W, Sah RL, Amiel D. Follow-up of osteochondral plug transfers in a goat model: a 6-month study. Am J Sports Med. 2004 Sep; 32(6):1440-50. PMID: 15310569.
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    68. Bae W, Law AW, Amiel D, Sah RL. Sensitivity of indentation testing to step-off edges and interface integrity in cartilage repair. Ann Biomed Eng. 2004 Mar; 32(3):360-9. PMID: 15095810.
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    69. Chen AC, Klisch SM, Bae W, Temple MM, McGowan KB, Gratz KR, Schumacher BL, Sah RL. Mechanical characterization of native and tissue-engineered cartilage. Methods Mol Med. 2004; 101:157-90. PMID: 15299215.
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    70. Li KW, Klein TJ, Chawla K, Nugent GE, Bae W, Sah RL. In vitro physical stimulation of tissue-engineered and native cartilage. Methods Mol Med. 2004; 100:325-52. PMID: 15280604.
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    71. Bae W, Temple MM, Amiel D, Coutts RD, Niederauer GG, Sah RL. Indentation testing of human cartilage: sensitivity to articular surface degeneration. Arthritis Rheum. 2003 Dec; 48(12):3382-94. PMID: 14673990.
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