-
Chromosomal inversion polymorphisms shape human brain morphology. Cell Rep. 2023 08 29; 42(8):112896.
Wang H, Makowski C, Zhang Y, Qi A, Kaufmann T, Smeland OB, Fiecas M, Yang J, Visscher PM, Chen CH. PMID: 37505983; PMCID: PMC10508191.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Circulating S100B levels at birth and risk of six major neuropsychiatric or neurological disorders: a two-sample Mendelian Randomization Study. Transl Psychiatry. 2023 05 24; 13(1):174.
Pan M, Roe JM, Nudel R, Schork AJ, Iakunchykova O, Fjell AM, Walhovd KB, Werge T, Chen CH, Benros ME, Wang Y. PMID: 37225692; PMCID: PMC10209162.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Larger cerebral cortex is genetically correlated with greater frontal area and dorsal thickness. Proc Natl Acad Sci U S A. 2023 03 14; 120(11):e2214834120.
Makowski C, Wang H, Srinivasan A, Qi A, Qiu Y, van der Meer D, Frei O, Zou J, Visscher PM, Yang J, Chen CH. PMID: 36893272; PMCID: PMC10089183.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Mapping the common gene networks that underlie related diseases. Nat Protoc. 2023 Jun; 18(6):1745-1759.
Rosenthal SB, Wright SN, Liu S, Churas C, Chilin-Fuentes D, Chen CH, Fisch KM, Pratt D, Kreisberg JF, Ideker T. PMID: 36653526; PMCID: PMC10257754.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Candidates for drug repurposing to address the cognitive symptoms in schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2023 01 10; 120:110637.
Koch E, Kauppi K, Chen CH. PMID: 36099967.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Clinical opportunity awaits at the intersection of genomics and brain imaging. J Psychiatry Neurosci. 2022 Jul-Aug; 47(4):E293-E298.
Makowski C, Wang H, Chen CH. PMID: 35948342; PMCID: PMC9377545.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Multivariate genome-wide association study on tissue-sensitive diffusion metrics highlights pathways that shape the human brain. Nat Commun. 2022 05 03; 13(1):2423.
Fan CC, Loughnan R, Makowski C, Pecheva D, Chen CH, Hagler DJ, Thompson WK, Parker N, van der Meer D, Frei O, Andreassen OA, Dale AM. PMID: 35505052; PMCID: PMC9065144.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Mapping the gene network landscape of Alzheimer's disease through integrating genomics and transcriptomics. PLoS Comput Biol. 2022 02; 18(2):e1009903.
Rosenthal SB, Wang H, Shi D, Liu C, Abagyan R, McEvoy LK, Chen CH. PMID: 35213535; PMCID: PMC8906581.
View in:
PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
-
Do aggregate, multimodal structural neuroimaging measures replicate regional developmental differences observed in highly cited cellular histological studies? Dev Cogn Neurosci. 2022 04; 54:101086.
Hagler DJ, Thompson WK, Chen CH, Reuter C, Akshoomoff N, Brown TT, Pediatric Imaging, Neurocognition, and Genetics Study. PMID: 35220023; PMCID: PMC8889098.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Discovery of genomic loci of the human cerebral cortex using genetically informed brain atlases. Science. 2022 02 04; 375(6580):522-528.
Makowski C, van der Meer D, Dong W, Wang H, Wu Y, Zou J, Liu C, Rosenthal SB, Hagler DJ, Fan CC, Kremen WS, Andreassen OA, Jernigan TL, Dale AM, Zhang K, Visscher PM, Yang J, Chen CH. PMID: 35113692; PMCID: PMC9469470.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansCells
-
Causal association of cognitive reserve on Alzheimer's disease with putative sex difference. Alzheimers Dement (Amst). 2021; 13(1):e12270.
Wang H, Rosenthal BS, Makowski C, Lo MT, Andreassen OA, Salem RM, McEvoy LK, Fiecas M, Chen CH. PMID: 35005200; PMCID: PMC8719428.
View in:
PubMed Mentions:
1
-
Interplay between the genetics of personality traits, severe psychiatric disorders and COVID-19 host genetics in the susceptibility to SARS-CoV-2 infection. BJPsych Open. 2021 Nov; 7(6):e188.
Heilbronner U, Streit F, Vogl T, Senner F, Schaupp SK, Reich-Erkelenz D, Papiol S, Oraki Kohshour M, Klöhn-Saghatolislam F, Kalman JL, Heilbronner M, Gade K, Comes AL, Budde M, Andlauer TFM, Anderson-Schmidt H, Adorjan K, Stürmer T, Loerbroks A, Amelang M, Poisel E, Foo J, Heilmann-Heimbach S, Forstner AJ, Degenhardt F, Zimmermann J, Wiltfang J, von Hagen M, Spitzer C, Schmauss M, Reininghaus E, Reimer J, Konrad C, Juckel G, Lang FU, Jäger M, Figge C, Fallgatter AJ, Dietrich DE, Dannlowski U, Baune BT, Arolt V, Anghelescu IG, Nöthen MM, Witt SH, Andreassen OA, Chen CH, Falkai P, Rietschel M, Schulze TG, Schulte EC. PMID: 34659794; PMCID: PMC8503053.
View in:
PubMed Mentions:
1
-
Atypical genomic cortical patterning in autism with poor early language outcome. Sci Adv. 2021 Sep 03; 7(36):eabh1663.
Lombardo MV, Eyler L, Pramparo T, Gazestani VH, Hagler DJ, Chen CH, Dale AM, Seidlitz J, Bethlehem RAI, Bertelsen N, Barnes CC, Lopez L, Campbell K, Lewis NE, Pierce K, Courchesne E. PMID: 34516910; PMCID: PMC8442861.
View in:
PubMed Mentions:
9 Fields:
-
View in:
PubMed Mentions:
5
-
Quantifying the Polygenic Architecture of the Human Cerebral Cortex: Extensive Genetic Overlap between Cortical Thickness and Surface Area. Cereb Cortex. 2020 09 03; 30(10):5597-5603.
van der Meer D, Frei O, Kaufmann T, Chen CH, Thompson WK, O'Connell KS, Monereo Sánchez J, Linden DEJ, Westlye LT, Dale AM, Andreassen OA. PMID: 32483632; PMCID: PMC7472200.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
-
Sex-dependent autosomal effects on clinical progression of Alzheimer's disease. Brain. 2020 07 01; 143(7):2272-2280.
Fan CC, Banks SJ, Thompson WK, Chen CH, McEvoy LK, Tan CH, Kukull W, Bennett DA, Farrer LA, Mayeux R, Schellenberg GD, Andreassen OA, Desikan R, Dale AM. PMID: 32591829; PMCID: PMC7364740.
View in:
PubMed Mentions:
30 Fields:
Translation:
Humans
-
Interactome overlap between schizophrenia and cognition. Schizophr Res. 2020 08; 222:167-174.
Koch E, Rosenthal B, Lundquist A, Chen CH, Kauppi K. PMID: 32546371.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
-
Cerebellar Volume Is Associated with Cognitive Decline in Mild Cognitive Impairment: Results from ADNI. Cerebellum. 2020 Apr; 19(2):217-225.
Lin CY, Chen CH, Tom SE, Kuo SH, Alzheimer’s Disease Neuroimaging Initiative. PMID: 31900856; PMCID: PMC7085462.
View in:
PubMed Mentions:
17 Fields:
Translation:
Humans
-
Continuity and Discontinuity in Human Cortical Development and Change From Embryonic Stages to Old Age. Cereb Cortex. 2019 08 14; 29(9):3879-3890.
Fjell AM, Chen CH, Sederevicius D, Sneve MH, Grydeland H, Krogsrud SK, Amlien I, Ferschmann L, Ness H, Folvik L, Beck D, Mowinckel AM, Tamnes CK, Westerhausen R, Håberg AK, Dale AM, Walhovd KB. PMID: 30357317.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
-
Cortical surface area variations within the dorsolateral prefrontal cortex are better predictors of future cognitive performance than fluid ability and working memory. Psicothema. 2019 Aug; 31(3):229-238.
Román FJ, Jaeggi SM, Martínez K, Privado J, Lewis LB, Chen CH, Escorial S, Kremen WS, Karama S, Colom R. PMID: 31292036.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Collagen Formation Assessed by N-Terminal Propeptide of Type 3 Procollagen Is a Heritable Trait and Is Associated With Liver Fibrosis Assessed by Magnetic Resonance Elastography. Hepatology. 2019 07; 70(1):127-141.
Caussy C, Bhargava M, Villesen IF, Gudmann NS, Leeming DJ, Karsdal MA, Faulkner C, Bao D, Liu A, Lo MT, Bettencourt R, Bassirian S, Richards L, Brenner DA, Chen CH, Sirlin CB, Loomba R. PMID: 30859582; PMCID: PMC6984974.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
-
Identification of genetic heterogeneity of Alzheimer's disease across age. Neurobiol Aging. 2019 12; 84:243.e1-243.e9.
Lo MT, Kauppi K, Fan CC, Sanyal N, Reas ET, Sundar VS, Lee WC, Desikan RS, McEvoy LK, Chen CH, Alzheimer's Disease Genetics Consortium. PMID: 30979435; PMCID: PMC6783343.
View in:
PubMed Mentions:
21 Fields:
Translation:
Humans
-
GWASinlps: non-local prior based iterative SNP selection tool for genome-wide association studies. Bioinformatics. 2019 01 01; 35(1):1-11.
Sanyal N, Lo MT, Kauppi K, Djurovic S, Andreassen OA, Johnson VE, Chen CH. PMID: 29931045; PMCID: PMC6298063.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia. Mol Psychiatry. 2020 03; 25(3):584-602.
Sønderby IE, Gústafsson Ó, Doan NT, Hibar DP, Martin-Brevet S, Abdellaoui A, Ames D, Amunts K, Andersson M, Armstrong NJ, Bernard M, Blackburn N, Blangero J, Boomsma DI, Bralten J, Brattbak HR, Brodaty H, Brouwer RM, Bülow R, Calhoun V, Caspers S, Cavalleri G, Chen CH, Cichon S, Ciufolini S, Corvin A, Crespo-Facorro B, Curran JE, Dale AM, Dalvie S, Dazzan P, de Geus EJC, de Zubicaray GI, de Zwarte SMC, Delanty N, den Braber A, Desrivières S, Donohoe G, Draganski B, Ehrlich S, Espeseth T, Fisher SE, Franke B, Frouin V, Fukunaga M, Gareau T, Glahn DC, Grabe H, Groenewold NA, Haavik J, Håberg A, Hashimoto R, Hehir-Kwa JY, Heinz A, Hillegers MHJ, Hoffmann P, Holleran L, Hottenga JJ, Hulshoff HE, Ikeda M, Jahanshad N, Jernigan T, Jockwitz C, Johansson S, Jonsdottir GA, Jönsson EG, Kahn R, Kaufmann T, Kelly S, Kikuchi M, Knowles EEM, Kolskår KK, Kwok JB, Hellard SL, Leu C, Liu J, Lundervold AJ, Lundervold A, Martin NG, Mather K, Mathias SR, McCormack M, McMahon KL, McRae A, Milaneschi Y, Moreau C, Morris D, Mothersill D, Mühleisen TW, Murray R, Nordvik JE, Nyberg L, Olde Loohuis LM, Ophoff R, Paus T, Pausova Z, Penninx B, Peralta JM, Pike B, Prieto C, Pudas S, Quinlan E, Quintana DS, Reinbold CS, Marques TR, Reymond A, Richard G, Rodriguez-Herreros B, Roiz-Santiañez R, Rokicki J, Rucker J, Sachdev P, Sanders AM, Sando SB, Schmaal L, Schofield PR, Schork AJ, Schumann G, Shin J, Shumskaya E, Sisodiya S, Steen VM, Stein DJ, Steinberg S, Strike L, Teumer A, Thalamuthu A, Tordesillas-Gutierrez D, Turner J, Ueland T, Uhlmann A, Ulfarsson MO, van 't Ent D, van der Meer D, van Haren NEM, Vaskinn A, Vassos E, Walters GB, Wang Y, Wen W, Whelan CD, Wittfeld K, Wright M, Yamamori H, Zayats T, Agartz I, Westlye LT, Jacquemont S, Djurovic S, Stefánsson H, Stefánsson K, Thompson P, Andreassen OA, 16p11.2 European Consortium, for the ENIGMA-CNV working group. PMID: 30283035; PMCID: PMC7042770.
View in:
PubMed Mentions:
28 Fields:
Translation:
HumansCells
-
Williams Syndrome neuroanatomical score associates with GTF2IRD1 in large-scale magnetic resonance imaging cohorts: a proof of concept for multivariate endophenotypes. Transl Psychiatry. 2018 06 08; 8(1):114.
Fan CC, Schork AJ, Brown TT, Spencer BE, Akshoomoff N, Chen CH, Kuperman JM, Hagler DJ, Steen VM, Le Hellard S, Håberg AK, Espeseth T, Andreassen OA, Dale AM, Jernigan TL, Halgren E, Pediatric Imaging, Neurocognition and Genetics Study, Alzheimer’s Disease Neuroimaging Initiative. PMID: 29884845; PMCID: PMC5993783.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Genetic Overlap Between Schizophrenia and Volumes of Hippocampus, Putamen, and Intracranial Volume Indicates Shared Molecular Genetic Mechanisms. Schizophr Bull. 2018 06 06; 44(4):854-864.
Smeland OB, Wang Y, Frei O, Li W, Hibar DP, Franke B, Bettella F, Witoelar A, Djurovic S, Chen CH, Thompson PM, Dale AM, Andreassen OA. PMID: 29136250; PMCID: PMC6007549.
View in:
PubMed Mentions:
48 Fields:
Translation:
Humans
-
Link between gut-microbiome derived metabolite and shared gene-effects with hepatic steatosis and fibrosis in NAFLD. Hepatology. 2018 09; 68(3):918-932.
Caussy C, Hsu C, Lo MT, Liu A, Bettencourt R, Ajmera VH, Bassirian S, Hooker J, Sy E, Richards L, Schork N, Schnabl B, Brenner DA, Sirlin CB, Chen CH, Loomba R, Genetics of NAFLD in Twins Consortium. PMID: 29572891; PMCID: PMC6151296.
View in:
PubMed Mentions:
88 Fields:
Translation:
Humans
-
Polygenic risk for psychiatric disorders correlates with executive function in typical development. Genes Brain Behav. 2019 04; 18(4):e12480.
Schork AJ, Brown TT, Hagler DJ, Thompson WK, Chen CH, Dale AM, Jernigan TL, Akshoomoff N, Pediatric Imaging, Neurocognition and Genetics Study. PMID: 29660215; PMCID: PMC6191376.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Beyond heritability: improving discoverability in imaging genetics. Hum Mol Genet. 2018 05 01; 27(R1):R22-R28.
Fan CC, Smeland OB, Schork AJ, Chen CH, Holland D, Lo MT, Sundar VS, Frei O, Jernigan TL, Andreassen OA, Dale AM. PMID: 29522091; PMCID: PMC5946904.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
-
Combining Polygenic Hazard Score With Volumetric MRI and Cognitive Measures Improves Prediction of Progression From Mild Cognitive Impairment to Alzheimer's Disease. Front Neurosci. 2018; 12:260.
Kauppi K, Fan CC, McEvoy LK, Holland D, Tan CH, Chen CH, Andreassen OA, Desikan RS, Dale AM, Alzheimer's Disease Neuroimaging Initiative. PMID: 29760643; PMCID: PMC5937163.
View in:
PubMed Mentions:
22
-
Revisiting Antipsychotic Drug Actions Through Gene Networks Associated With Schizophrenia. Am J Psychiatry. 2018 07 01; 175(7):674-682.
Kauppi K, Rosenthal SB, Lo MT, Sanyal N, Jiang M, Abagyan R, McEvoy LK, Andreassen OA, Chen CH. PMID: 29495895; PMCID: PMC6028303.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
The genetics of human personality. Genes Brain Behav. 2018 03; 17(3):e12439.
Sanchez-Roige S, Gray JC, MacKillop J, Chen CH, Palmer AA. PMID: 29152902; PMCID: PMC7012279.
View in:
PubMed Mentions:
28 Fields:
Translation:
HumansCells
-
Leveraging genome characteristics to improve gene discovery for putamen subcortical brain structure. Sci Rep. 2017 Nov 16; 7(1):15736.
Chen CH, Wang Y, Lo MT, Schork A, Fan CC, Holland D, Kauppi K, Smeland OB, Djurovic S, Sanyal N, Hibar DP, Thompson PM, Thompson WK, Andreassen OA, Dale AM. PMID: 29147026; PMCID: PMC5691156.
View in:
PubMed Mentions:
9 Fields:
Translation:
Humans
-
Modeling prior information of common genetic variants improves gene discovery for neuroticism. Hum Mol Genet. 2017 11 15; 26(22):4530-4539.
Lo MT, Wang Y, Kauppi K, Sanyal N, Fan CC, Smeland OB, Schork A, Holland D, Hinds DA, Tung JY, Andreassen OA, Dale AM, Chen CH. PMID: 28973307; PMCID: PMC5886256.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Identification of Genetic Loci Jointly Influencing Schizophrenia Risk and the Cognitive Traits of Verbal-Numerical Reasoning, Reaction Time, and General Cognitive Function. JAMA Psychiatry. 2017 10 01; 74(10):1065-1075.
Smeland OB, Frei O, Kauppi K, Hill WD, Li W, Wang Y, Krull F, Bettella F, Eriksen JA, Witoelar A, Davies G, Fan CC, Thompson WK, Lam M, Lencz T, Chen CH, Ueland T, Jönsson EG, Djurovic S, Deary IJ, Dale AM, Andreassen OA, NeuroCHARGE (Cohorts for Heart and Aging Research in Genomic Epidemiology) Cognitive Working Group. PMID: 28746715; PMCID: PMC5710474.
View in:
PubMed Mentions:
64 Fields:
Translation:
Humans
-
Nonalcoholic fatty liver disease with cirrhosis increases familial risk for advanced fibrosis. J Clin Invest. 2017 Jun 30; 127(7):2697-2704.
Caussy C, Soni M, Cui J, Bettencourt R, Schork N, Chen CH, Ikhwan MA, Bassirian S, Cepin S, Gonzalez MP, Mendler M, Kono Y, Vodkin I, Mekeel K, Haldorson J, Hemming A, Andrews B, Salotti J, Richards L, Brenner DA, Sirlin CB, Loomba R, Familial NAFLD Cirrhosis Research Consortium. PMID: 28628033; PMCID: PMC5490764.
View in:
PubMed Mentions:
70 Fields:
Translation:
HumansCTClinical Trials
-
Identification of genetic loci shared between schizophrenia and the Big Five personality traits. Sci Rep. 2017 05 22; 7(1):2222.
Smeland OB, Wang Y, Lo MT, Li W, Frei O, Witoelar A, Tesli M, Hinds DA, Tung JY, Djurovic S, Chen CH, Dale AM, Andreassen OA. PMID: 28533504; PMCID: PMC5440373.
View in:
PubMed Mentions:
26 Fields:
Translation:
Humans
-
Gut Microbiome-Based Metagenomic Signature for Non-invasive Detection of Advanced Fibrosis in Human Nonalcoholic Fatty Liver Disease. Cell Metab. 2017 May 02; 25(5):1054-1062.e5.
Loomba R, Seguritan V, Li W, Long T, Klitgord N, Bhatt A, Dulai PS, Caussy C, Bettencourt R, Highlander SK, Jones MB, Sirlin CB, Schnabl B, Brinkac L, Schork N, Chen CH, Brenner DA, Biggs W, Yooseph S, Venter JC, Nelson KE. PMID: 28467925; PMCID: PMC5502730.
View in:
PubMed Mentions:
391 Fields:
Translation:
HumansCells
-
Genetic evidence for role of integration of fast and slow neurotransmission in schizophrenia. Mol Psychiatry. 2017 06; 22(6):792-801.
Devor A, Andreassen OA, Wang Y, Mäki-Marttunen T, Smeland OB, Fan CC, Schork AJ, Holland D, Thompson WK, Witoelar A, Chen CH, Desikan RS, McEvoy LK, Djurovic S, Greengard P, Svenningsson P, Einevoll GT, Dale AM. PMID: 28348379; PMCID: PMC5495879.
View in:
PubMed Mentions:
34 Fields:
Translation:
HumansCells
-
Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score. PLoS Med. 2017 03; 14(3):e1002258.
Desikan RS, Fan CC, Wang Y, Schork AJ, Cabral HJ, Cupples LA, Thompson WK, Besser L, Kukull WA, Holland D, Chen CH, Brewer JB, Karow DS, Kauppi K, Witoelar A, Karch CM, Bonham LW, Yokoyama JS, Rosen HJ, Miller BL, Dillon WP, Wilson DM, Hess CP, Pericak-Vance M, Haines JL, Farrer LA, Mayeux R, Hardy J, Goate AM, Hyman BT, Schellenberg GD, McEvoy LK, Andreassen OA, Dale AM. PMID: 28323831; PMCID: PMC5360219.
View in:
PubMed Mentions:
177 Fields:
Translation:
Humans
-
Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders. Nat Genet. 2017 01; 49(1):152-156.
Lo MT, Hinds DA, Tung JY, Franz C, Fan CC, Wang Y, Smeland OB, Schork A, Holland D, Kauppi K, Sanyal N, Escott-Price V, Smith DJ, O'Donovan M, Stefansson H, Bjornsdottir G, Thorgeirsson TE, Stefansson K, McEvoy LK, Dale AM, Andreassen OA, Chen CH. PMID: 27918536; PMCID: PMC5278898.
View in:
PubMed Mentions:
139 Fields:
Translation:
Humans
-
Go/No Go task performance predicts cortical thickness in the caudal inferior frontal gyrus in young adults with and without ADHD. Brain Imaging Behav. 2016 09; 10(3):880-92.
Newman E, Jernigan TL, Lisdahl KM, Tamm L, Tapert SF, Potkin SG, Mathalon D, Molina B, Bjork J, Castellanos FX, Swanson J, Kuperman JM, Bartsch H, Chen CH, Dale AM, Epstein JN, MTA Neuroimaging Group. PMID: 26404018; PMCID: PMC4808505.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Conservation of distinct genetically-mediated human cortical pattern. PLoS Genet. 2016; 12(7).
Peng Q, Schork A, Bartsch H, Lo MT, Panizzon MS, Pediatric Imaging, Neurocognition and Genetics Study, Alzheimer’s Disease Neuroimaging Initiative, Westlye LT, Kremen WS, Jernigan TL, Hellard SL, Steen VM, Espeseth T, Huentelman M, Håberg AK, Agartz I, Djurovic S, Andreassen OA, Dale AM, Schork NJ, and Chen CH. .
-
Conservation of Distinct Genetically-Mediated Human Cortical Pattern. PLoS Genet. 2016 07; 12(7):e1006143.
Peng Q, Schork A, Bartsch H, Lo MT, Panizzon MS, Pediatric Imaging, Neurocognition and Genetics Study, Alzheimer’s Disease Neuroimaging Initiative, Westlye LT, Kremen WS, Jernigan TL, Le Hellard S, Steen VM, Espeseth T, Huentelman M, Håberg AK, Agartz I, Djurovic S, Andreassen OA, Dale AM, Schork NJ, Chen CH. PMID: 27459196; PMCID: PMC4961377.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCells
-
Global Visual Motion Sensitivity: Associations with Parietal Area and Children's Mathematical Cognition. J Cogn Neurosci. 2016 Dec; 28(12):1897-1908.
Braddick O, Atkinson J, Newman E, Akshoomoff N, Kuperman JM, Bartsch H, Chen CH, Dale AM, Jernigan TL. PMID: 27458748; PMCID: PMC5419429.
View in:
PubMed Mentions:
15 Fields:
Translation:
Humans
-
Shared genetic effects between hepatic steatosis and fibrosis: A prospective twin study. Hepatology. 2016 11; 64(5):1547-1558.
Cui J, Chen CH, Lo MT, Schork N, Bettencourt R, Gonzalez MP, Bhatt A, Hooker J, Shaffer K, Nelson KE, Long MT, Brenner DA, Sirlin CB, Loomba R. PMID: 27315352; PMCID: PMC5090982.
View in:
PubMed Mentions:
36 Fields:
Translation:
Humans
-
Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease. JAMA Neurol. 2016 06 01; 73(6):691-7.
Yokoyama JS, Wang Y, Schork AJ, Thompson WK, Karch CM, Cruchaga C, McEvoy LK, Witoelar A, Chen CH, Holland D, Brewer JB, Franke A, Dillon WP, Wilson DM, Mukherjee P, Hess CP, Miller Z, Bonham LW, Shen J, Rabinovici GD, Rosen HJ, Miller BL, Hyman BT, Schellenberg GD, Karlsen TH, Andreassen OA, Dale AM, Desikan RS, Alzheimer’s Disease Neuroimaging Initiative. PMID: 27088644; PMCID: PMC4905783.
View in:
PubMed Mentions:
95 Fields:
Translation:
Humans
-
Estimating Effect Sizes and Expected Replication Probabilities from GWAS Summary Statistics. Front Genet. 2016; 7:15.
Holland D, Wang Y, Thompson WK, Schork A, Chen CH, Lo MT, Witoelar A, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Enhancing Neuro Imaging Genetics through Meta Analysis Consortium, Werge T, O'Donovan M, Andreassen OA, Dale AM. PMID: 26909100; PMCID: PMC4754432.
View in:
PubMed Mentions:
22
-
Is bigger always better? The importance of cortical configuration with respect to cognitive ability. Neuroimage. 2016 Apr 01; 129:356-366.
Vuoksimaa E, Panizzon MS, Chen CH, Fiecas M, Eyler LT, Fennema-Notestine C, Hagler DJ, Franz CE, Jak AJ, Lyons MJ, Neale MC, Rinker DA, Thompson WK, Tsuang MT, Dale AM, Kremen WS. PMID: 26827810; PMCID: PMC4838639.
View in:
PubMed Mentions:
18 Fields:
Translation:
Humans
-
Leveraging Genomic Annotations and Pleiotropic Enrichment for Improved Replication Rates in Schizophrenia GWAS. PLoS Genet. 2016 Jan; 12(1):e1005803.
Wang Y, Thompson WK, Schork AJ, Holland D, Chen CH, Bettella F, Desikan RS, Li W, Witoelar A, Zuber V, Devor A, Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium, Enhancing Neuro Imaging Genetics through Meta Analysis Consortium, Nöthen MM, Rietschel M, Chen Q, Werge T, Cichon S, Weinberger DR, Djurovic S, O'Donovan M, Visscher PM, Andreassen OA, Dale AM. PMID: 26808560; PMCID: PMC4726519.
View in:
PubMed Mentions:
26 Fields:
Translation:
Humans
-
Gray matter responsiveness to adaptive working memory training: a surface-based morphometry study. Brain Struct Funct. 2016 12; 221(9):4369-4382.
Román FJ, Lewis LB, Chen CH, Karama S, Burgaleta M, Martínez K, Lepage C, Jaeggi SM, Evans AC, Kremen WS, Colom R. PMID: 26701168; PMCID: PMC4919225.
View in:
PubMed Mentions:
9 Fields:
Translation:
Humans
-
Development and aging of cortical thickness correspond to genetic organization patterns. Proc Natl Acad Sci U S A. 2015 Dec 15; 112(50):15462-7.
Fjell AM, Grydeland H, Krogsrud SK, Amlien I, Rohani DA, Ferschmann L, Storsve AB, Tamnes CK, Sala-Llonch R, Due-Tønnessen P, Bjørnerud A, Sølsnes AE, Håberg AK, Skranes J, Bartsch H, Chen CH, Thompson WK, Panizzon MS, Kremen WS, Dale AM, Walhovd KB. PMID: 26575625; PMCID: PMC4687601.
View in:
PubMed Mentions:
119 Fields:
Translation:
Humans
-
Heritability of Hepatic Fibrosis and Steatosis Based on a Prospective Twin Study. Gastroenterology. 2015 Dec; 149(7):1784-93.
Loomba R, Schork N, Chen CH, Bettencourt R, Bhatt A, Ang B, Nguyen P, Hernandez C, Richards L, Salotti J, Lin S, Seki E, Nelson KE, Sirlin CB, Brenner D, Genetics of NAFLD in Twins Consortium. PMID: 26299412; PMCID: PMC4663110.
View in:
PubMed Mentions:
151 Fields:
Translation:
Humans
-
Genetic network properties of the human cortex based on regional thickness and surface area measures. Front Hum Neurosci. 2015; 9:440.
Docherty AR, Sawyers CK, Panizzon MS, Neale MC, Eyler LT, Fennema-Notestine C, Franz CE, Chen CH, McEvoy LK, Verhulst B, Tsuang MT, Kremen WS. PMID: 26347632; PMCID: PMC4542323.
View in:
PubMed Mentions:
5
-
Large-scale genomics unveil polygenic architecture of human cortical surface area. Nat Commun. 2015 Jul 20; 6:7549.
Chen CH, Peng Q, Schork AJ, Lo MT, Fan CC, Wang Y, Desikan RS, Bettella F, Hagler DJ, Pediatric Imaging, Neurocognition and Genetics Study, Alzheimer’s Disease Neuroimaging Initiative, Westlye LT, Kremen WS, Jernigan TL, Le Hellard S, Steen VM, Espeseth T, Huentelman M, Håberg AK, Agartz I, Djurovic S, Andreassen OA, Schork N, Dale AM, Pediatric Imaging Neurocognition and Genetics Study, Alzheimer's Disease Neuroimaging Initiative. PMID: 26189703; PMCID: PMC4518289.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansCells
-
Anxiety is related to indices of cortical maturation in typically developing children and adolescents. Brain Struct Funct. 2016 07; 221(6):3013-25.
Newman E, Thompson WK, Bartsch H, Hagler DJ, Chen CH, Brown TT, Kuperman JM, McCabe C, Chung Y, Libiger O, Akshoomoff N, Bloss CS, Casey BJ, Chang L, Ernst TM, Frazier JA, Gruen JR, Kennedy DN, Murray SS, Sowell ER, Schork N, Kenet T, Kaufmann WE, Mostofsky S, Amaral DG, Dale AM, Jernigan TL. PMID: 26183468; PMCID: PMC5064818.
View in:
PubMed Mentions:
27 Fields:
Translation:
Humans
-
Modeling the 3D geometry of the cortical surface with genetic ancestry. Curr Biol. 2015 Aug 03; 25(15):1988-92.
Fan CC, Bartsch H, Schork AJ, Chen CH, Wang Y, Lo MT, Brown TT, Kuperman JM, Hagler DJ, Schork NJ, Jernigan TL, Dale AM, Pediatric Imaging, Neurocognition, and Genetics Study. PMID: 26166778; PMCID: PMC4786069.
View in:
PubMed Mentions:
16 Fields:
Translation:
Humans
-
Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease. Circulation. 2015 Jun 09; 131(23):2061-2069.
Desikan RS, Schork AJ, Wang Y, Thompson WK, Dehghan A, Ridker PM, Chasman DI, McEvoy LK, Holland D, Chen CH, Karow DS, Brewer JB, Hess CP, Williams J, Sims R, O'Donovan MC, Choi SH, Bis JC, Ikram MA, Gudnason V, DeStefano AL, van der Lee SJ, Psaty BM, van Duijn CM, Launer L, Seshadri S, Pericak-Vance MA, Mayeux R, Haines JL, Farrer LA, Hardy J, Ulstein ID, Aarsland D, Fladby T, White LR, Sando SB, Rongve A, Witoelar A, Djurovic S, Hyman BT, Snaedal J, Steinberg S, Stefansson H, Stefansson K, Schellenberg GD, Andreassen OA, Dale AM, Inflammation working group, IGAP and DemGene Investigators. PMID: 25862742; PMCID: PMC4677995.
View in:
PubMed Mentions:
75 Fields:
Translation:
Humans
-
Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus. Mol Psychiatry. 2015 Dec; 20(12):1588-95.
Desikan RS, Schork AJ, Wang Y, Witoelar A, Sharma M, McEvoy LK, Holland D, Brewer JB, Chen CH, Thompson WK, Harold D, Williams J, Owen MJ, O'Donovan MC, Pericak-Vance MA, Mayeux R, Haines JL, Farrer LA, Schellenberg GD, Heutink P, Singleton AB, Brice A, Wood NW, Hardy J, Martinez M, Choi SH, DeStefano A, Ikram MA, Bis JC, Smith A, Fitzpatrick AL, Launer L, van Duijn C, Seshadri S, Ulstein ID, Aarsland D, Fladby T, Djurovic S, Hyman BT, Snaedal J, Stefansson H, Stefansson K, Gasser T, Andreassen OA, Dale AM, ADNI, ADGC, GERAD, CHARGE and IPDGC Investigators. PMID: 25687773; PMCID: PMC4539304.
View in:
PubMed Mentions:
80 Fields:
Translation:
HumansCells
-
Heritable influences on amygdala and orbitofrontal cortex contribute to genetic variation in core dimensions of personality. Neuroimage. 2014 Dec; 103:309-315.
Lewis GJ, Panizzon MS, Eyler L, Fennema-Notestine C, Chen CH, Neale MC, Jernigan TL, Lyons MJ, Dale AM, Kremen WS, Franz CE. PMID: 25263286; PMCID: PMC4745648.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
-
The Genetic Association Between Neocortical Volume and General Cognitive Ability Is Driven by Global Surface Area Rather Than Thickness. Cereb Cortex. 2015 Aug; 25(8):2127-37.
Vuoksimaa E, Panizzon MS, Chen CH, Fiecas M, Eyler LT, Fennema-Notestine C, Hagler DJ, Fischl B, Franz CE, Jak A, Lyons MJ, Neale MC, Rinker DA, Thompson WK, Tsuang MT, Dale AM, Kremen WS. PMID: 24554725; PMCID: PMC4494025.
View in:
PubMed Mentions:
38 Fields:
Translation:
Humans
-
Conceptual and data-based investigation of genetic influences and brain asymmetry: a twin study of multiple structural phenotypes. J Cogn Neurosci. 2014 May; 26(5):1100-17.
Eyler LT, Vuoksimaa E, Panizzon MS, Fennema-Notestine C, Neale MC, Chen CH, Jak A, Franz CE, Lyons MJ, Thompson WK, Spoon KM, Fischl B, Dale AM, Kremen WS. PMID: 24283492; PMCID: PMC3999438.
View in:
PubMed Mentions:
33 Fields:
Translation:
Humans
-
View in:
PubMed Mentions:
27 Fields:
Translation:
Humans
-
Genetic topography of brain morphology. Proc Natl Acad Sci U S A. 2013 Oct 15; 110(42):17089-94.
Chen CH, Fiecas M, Gutiérrez ED, Panizzon MS, Eyler LT, Vuoksimaa E, Thompson WK, Fennema-Notestine C, Hagler DJ, Jernigan TL, Neale MC, Franz CE, Lyons MJ, Fischl B, Tsuang MT, Dale AM, Kremen WS. PMID: 24082094; PMCID: PMC3801007.
View in:
PubMed Mentions:
114 Fields:
Translation:
HumansCTClinical Trials
-
Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate. PLoS Genet. 2013 Apr; 9(4):e1003455.
Andreassen OA, Thompson WK, Schork AJ, Ripke S, Mattingsdal M, Kelsoe JR, Kendler KS, O'Donovan MC, Rujescu D, Werge T, Sklar P, Psychiatric Genomics Consortium (PGC), Bipolar Disorder and Schizophrenia Working Groups, Roddey JC, Chen CH, McEvoy L, Desikan RS, Djurovic S, Dale AM. PMID: 23637625; PMCID: PMC3636100.
View in:
PubMed Mentions:
173 Fields:
Translation:
Humans
-
Cognitive reserve moderates the association between hippocampal volume and episodic memory in middle age. Neuropsychologia. 2013 May; 51(6):1124-31.
Vuoksimaa E, Panizzon MS, Chen CH, Eyler LT, Fennema-Notestine C, Fiecas MJ, Fischl B, Franz CE, Grant MD, Jak AJ, Lyons MJ, Neale MC, Thompson WK, Tsuang MT, Xian H, Dale AM, Kremen WS. PMID: 23499725; PMCID: PMC3660613.
View in:
PubMed Mentions:
19 Fields:
Translation:
Humans
-
A comparison of heritability maps of cortical surface area and thickness and the influence of adjustment for whole brain measures: a magnetic resonance imaging twin study. Twin Res Hum Genet. 2012 Jun; 15(3):304-14.
Eyler LT, Chen CH, Panizzon MS, Fennema-Notestine C, Neale MC, Jak A, Jernigan TL, Fischl B, Franz CE, Lyons MJ, Grant M, Prom-Wormley E, Seidman LJ, Tsuang MT, Fiecas MJ, Dale AM, Kremen WS. PMID: 22856366; PMCID: PMC3549553.
View in:
PubMed Mentions:
62 Fields:
Translation:
Humans
-
Hierarchical genetic organization of human cortical surface area. Science. 2012 Mar 30; 335(6076):1634-6.
Chen CH, Gutierrez ED, Thompson W, Panizzon MS, Jernigan TL, Eyler LT, Fennema-Notestine C, Jak AJ, Neale MC, Franz CE, Lyons MJ, Grant MD, Fischl B, Seidman LJ, Tsuang MT, Kremen WS, Dale AM. PMID: 22461613; PMCID: PMC3690329.
View in:
PubMed Mentions:
153 Fields:
Translation:
Humans
-
Genetic and environmental influences of white and gray matter signal contrast: a new phenotype for imaging genetics? Neuroimage. 2012 Apr 15; 60(3):1686-95.
Panizzon MS, Fennema-Notestine C, Kubarych TS, Chen CH, Eyler LT, Fischl B, Franz CE, Grant MD, Hamza S, Jak A, Jernigan TL, Lyons MJ, Neale MC, Prom-Wormley EC, Seidman L, Tsuang MT, Wu H, Xian H, Dale AM, Kremen WS. PMID: 22500923; PMCID: PMC3328105.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansCells
-
Genetic influences on cortical regionalization in the human brain. Neuron. 2011 Nov 17; 72(4):537-44.
Chen CH, Panizzon MS, Eyler LT, Jernigan TL, Thompson W, Fennema-Notestine C, Jak AJ, Neale MC, Franz CE, Hamza S, Lyons MJ, Grant MD, Fischl B, Seidman LJ, Tsuang MT, Kremen WS, Dale AM. PMID: 22099457; PMCID: PMC3222857.
View in:
PubMed Mentions:
63 Fields:
Translation:
HumansAnimals
-
Genetic influences on hippocampal volume differ as a function of testosterone level in middle-aged men. Neuroimage. 2012 Jan 16; 59(2):1123-31.
Panizzon MS, Hauger RL, Eaves LJ, Chen CH, Dale AM, Eyler LT, Fischl B, Fennema-Notestine C, Franz CE, Grant MD, Jacobson KC, Jak AJ, Lyons MJ, Mendoza SP, Neale MC, Prom-Wormley E, Seidman LJ, Tsuang MT, Xian H, Kremen WS. PMID: 21983185; PMCID: PMC3230702.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Genetic and environmental contributions to regional cortical surface area in humans: a magnetic resonance imaging twin study. Cereb Cortex. 2011 Oct; 21(10):2313-21.
Eyler LT, Prom-Wormley E, Panizzon MS, Kaup AR, Fennema-Notestine C, Neale MC, Jernigan TL, Fischl B, Franz CE, Lyons MJ, Grant M, Stevens A, Pacheco J, Perry ME, Schmitt JE, Seidman LJ, Thermenos HW, Tsuang MT, Chen CH, Thompson WK, Jak A, Dale AM, Kremen WS. PMID: 21378112; PMCID: PMC3169660.
View in:
PubMed Mentions:
54 Fields:
Translation:
HumansAnimals
-
A quantitative meta-analysis of fMRI studies in bipolar disorder. Bipolar Disord. 2011 Feb; 13(1):1-15.
Chen CH, Suckling J, Lennox BR, Ooi C, Bullmore ET. PMID: 21320248.
View in:
PubMed Mentions:
173 Fields:
Translation:
Humans
-
Frontoparietal activation distinguishes face and space from artifact concepts. J Cogn Neurosci. 2011 Sep; 23(9):2558-68.
Chen CH, Zeki S. PMID: 21254806; PMCID: PMC3473322.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Presence of ApoE ε4 allele associated with thinner frontal cortex in middle age. J Alzheimers Dis. 2011; 26 Suppl 3:49-60.
Fennema-Notestine C, Panizzon MS, Thompson WR, Chen CH, Eyler LT, Fischl B, Franz CE, Grant MD, Jak AJ, Jernigan TL, Lyons MJ, Neale MC, Seidman LJ, Tsuang MT, Xian H, Dale AM, Kremen WS. PMID: 21971450; PMCID: PMC3302177.
View in:
PubMed Mentions:
46 Fields:
Translation:
Humans
-
A longitudinal fMRI study of the manic and euthymic states of bipolar disorder. Bipolar Disord. 2010 May; 12(3):344-7.
Chen CH, Suckling J, Ooi C, Jacob R, Lupson V, Bullmore ET, Lennox BR. PMID: 20565443.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
-
Components of variance in a multicentre functional MRI study and implications for calculation of statistical power. Hum Brain Mapp. 2008 Oct; 29(10):1111-22.
Suckling J, Ohlssen D, Andrew C, Johnson G, Williams SC, Graves M, Chen CH, Spiegelhalter D, Bullmore E. PMID: 17680602; PMCID: PMC6871081.
View in:
PubMed Mentions:
25 Fields:
Translation:
Humans
-
Functional coupling of the amygdala in depressed patients treated with antidepressant medication. Neuropsychopharmacology. 2008 Jul; 33(8):1909-18.
Chen CH, Suckling J, Ooi C, Fu CH, Williams SC, Walsh ND, Mitterschiffthaler MT, Pich EM, Bullmore E. PMID: 17987064.
View in:
PubMed Mentions:
79 Fields:
Translation:
Humans
-
Neurocognitive endophenotypes of obsessive-compulsive disorder. Brain. 2007 Dec; 130(Pt 12):3223-36.
Menzies L, Achard S, Chamberlain SR, Fineberg N, Chen CH, del Campo N, Sahakian BJ, Robbins TW, Bullmore E. PMID: 17855376.
View in:
PubMed Mentions:
149 Fields:
Translation:
Humans
-
Brain imaging correlates of depressive symptom severity and predictors of symptom improvement after antidepressant treatment. Biol Psychiatry. 2007 Sep 01; 62(5):407-14.
Chen CH, Ridler K, Suckling J, Williams S, Fu CH, Merlo-Pich E, Bullmore E. PMID: 17217921.
View in:
PubMed Mentions:
128 Fields:
Translation:
HumansCTClinical Trials
-
Statistical neuroanatomy of the human inferior frontal gyrus and probabilistic atlas in a standard stereotaxic space. Hum Brain Mapp. 2007 Jan; 28(1):34-48.
Hammers A, Chen CH, Lemieux L, Allom R, Vossos S, Free SL, Myers R, Brooks DJ, Duncan JS, Koepp MJ. PMID: 16671082; PMCID: PMC6871382.
View in:
PubMed Mentions:
27 Fields:
Translation:
Humans
-
Explicit and implicit facial affect recognition in manic and depressed States of bipolar disorder: a functional magnetic resonance imaging study. Biol Psychiatry. 2006 Jan 01; 59(1):31-9.
Chen CH, Lennox B, Jacob R, Calder A, Lupson V, Bisbrown-Chippendale R, Suckling J, Bullmore E. PMID: 16112653.
View in:
PubMed Mentions:
73 Fields:
Translation:
Humans