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Hongxu Xian

Title(s)Postdoctoral Scholar, Pharmacology
SchoolHealth Sciences
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Franz CE, Xian H, Lew D, Hatton SN, Puckett O, Whitsel N, Beck A, Dale AM, Fang B, Fennema-Notestine C, Hauger RL, Jacobson KC, Lyons MJ, Reynolds CA, Kremen WS. Body mass trajectories and cortical thickness in middle-aged men: a 42-year longitudinal study starting in young adulthood. Neurobiol Aging. 2019 07; 79:11-21. PMID: 31026618.
      View in: PubMed
    2. Franz CE, Hatton SN, Hauger RL, Kredlow MA, Dale AM, Eyler L, McEvoy LK, Fennema-Notestine C, Hagler D, Jacobson KC, McKenzie RE, Panizzon MS, Gustavson DE, Xian H, Toomey R, Beck A, Stevens S, Tu X, Lyons MJ, Kremen WS. Posttraumatic stress symptom persistence across 24 years: association with brain structures. Brain Imaging Behav. 2019 Mar 04. PMID: 30830577.
      View in: PubMed
    3. Gustavson DE, Franz CE, Panizzon MS, Reynolds CA, Xian H, Jacobson KC, Toomey R, Lyons MJ, Kremen WS. Genetic and Environmental Associations Among Executive Functions, Trait Anxiety, and Depression Symptoms in Middle Age. Clin Psychol Sci. 2019 Jan; 7(1):127-142. PMID: 30923645.
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    4. Gustavson DE, Panizzon MS, Elman JA, Franz CE, Beck A, Reynolds CA, Jacobson KC, Xian H, Toomey R, Lyons MJ, Kremen WS. Genetic and Environmental Influences on Verbal Fluency in Middle Age: A Longitudinal Twin Study. Behav Genet. 2018 Sep; 48(5):361-373. PMID: 29922985.
      View in: PubMed
    5. Elman JA, Jak AJ, Panizzon MS, Tu XM, Chen T, Reynolds CA, Gustavson DE, Franz CE, Hatton SN, Jacobson KC, Toomey R, McKenzie R, Xian H, Lyons MJ, Kremen WS. Underdiagnosis of mild cognitive impairment: A consequence of ignoring practice effects. Alzheimers Dement (Amst). 2018; 10:372-381. PMID: 30003138.
      View in: PubMed
    6. Panizzon MS, Hauger RL, Xian H, Jacobson K, Lyons MJ, Franz CE, Kremen WS. Interactive effects of testosterone and cortisol on hippocampal volume and episodic memory in middle-aged men. Psychoneuroendocrinology. 2018 05; 91:115-122. PMID: 29547742.
      View in: PubMed
    7. Gustavson DE, Panizzon MS, Elman JA, Franz CE, Reynolds CA, Jacobson KC, Friedman NP, Xian H, Toomey R, Lyons MJ, Kremen WS. Stability of genetic and environmental influences on executive functions in midlife. Psychol Aging. 2018 03; 33(2):219-231. PMID: 29658745.
      View in: PubMed
    8. Gustavson DE, Panizzon MS, Franz CE, Friedman NP, Reynolds CA, Jacobson KC, Xian H, Lyons MJ, Kremen WS. Genetic and environmental architecture of executive functions in midlife. Neuropsychology. 2018 Jan; 32(1):18-30. PMID: 28857599.
      View in: PubMed
    9. Rana BK, Panizzon MS, Franz CE, Spoon KM, Jacobson KC, Xian H, Ancoli-Israel S, Lyons M, Kremen WS. Association of Sleep Quality on Memory-Related Executive Functions in Middle Age. J Int Neuropsychol Soc. 2018 Jan; 24(1):67-76. PMID: 28760172.
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    10. Fennema-Notestine C, McEvoy LK, Notestine R, Panizzon MS, Yau WW, Franz CE, Lyons MJ, Eyler LT, Neale MC, Xian H, McKenzie RE, Kremen WS. White matter disease in midlife is heritable, related to hypertension, and shares some genetic influence with systolic blood pressure. Neuroimage Clin. 2016; 12:737-745. PMID: 27790395.
      View in: PubMed
    11. Panizzon MS, Hauger RL, Sailors M, Lyons MJ, Jacobson KC, Murray McKenzie R, Rana B, Vasilopoulos T, Vuoksimaa E, Xian H, Kremen WS, Franz CE. A new look at the genetic and environmental coherence of metabolic syndrome components. Obesity (Silver Spring). 2015 Dec; 23(12):2499-507. PMID: 26524476; PMCID: PMC4701648 [Available on 12/01/16].
    12. Panizzon MS, Neale MC, Docherty AR, Franz CE, Jacobson KC, Toomey R, Xian H, Vasilopoulos T, Rana BK, McKenzie R, Lyons MJ, Kremen WS. Genetic and environmental architecture of changes in episodic memory from middle to late middle age. Psychol Aging. 2015 Jun; 30(2):286-300. PMID: 25938244; PMCID: PMC4451379.
    13. Jak AJ, Panizzon MS, Spoon KM, Fennema-Notestine C, Franz CE, Thompson WK, Jacobson KC, Xian H, Eyler LT, Vuoksimaa E, Toomey R, Lyons MJ, Neale MC, Tsuang MT, Dale AM, Kremen WS. Hippocampal atrophy varies by neuropsychologically defined MCI among men in their 50s. Am J Geriatr Psychiatry. 2015 May; 23(5):456-65. PMID: 25306196; PMCID: PMC4345132.
    14. Kremen WS, Jak AJ, Panizzon MS, Spoon KM, Franz CE, Thompson WK, Jacobson KC, Vasilopoulos T, Vuoksimaa E, Xian H, Toomey R, Lyons MJ. Authors' response to: commentary by Johnson et al. Int J Epidemiol. 2014 Apr; 43(2):612-3. PMID: 24760875; PMCID: PMC3997381.
    15. Franz CE, Lyons MJ, Spoon KM, Hauger RL, Jacobson KC, Lohr JB, McKenzie R, Panizzon MS, Thompson WK, Tsuang MT, Vasilopoulos T, Vuoksimaa E, Xian H, Kremen WS. Post-traumatic stress symptoms and adult attachment: a 24-year longitudinal study. Am J Geriatr Psychiatry. 2014 Dec; 22(12):1603-12. PMID: 24636844; PMCID: PMC4138283.
    16. Rana BK, Dhamija A, Panizzon MS, Spoon KM, Vasilopoulos T, Franz CE, Grant MD, Jacobson KC, Kim K, Lyons MJ, McCaffery JM, Stein PK, Xian H, O'Connor DT, Kremen WS. Imputing observed blood pressure for antihypertensive treatment: impact on population and genetic analyses. Am J Hypertens. 2014 Jun; 27(6):828-37. PMID: 24532572; PMCID: PMC4017930.
    17. Panizzon MS, Vuoksimaa E, Spoon KM, Jacobson KC, Lyons MJ, Franz CE, Xian H, Vasilopoulos T, Kremen WS. Genetic and Environmental Influences of General Cognitive Ability: Is g a valid latent construct? Intelligence. 2014; 43:65-76. PMID: 24791031.
      View in: PubMed
    18. Panizzon MS, Hauger R, Xian H, Vuoksimaa E, Spoon KM, Mendoza SP, Jacobson KC, Vasilopoulos T, Rana BK, McKenzie R, McCaffery JM, Lyons MJ, Kremen WS, Franz CE. Interaction of APOE genotype and testosterone on episodic memory in middle-aged men. Neurobiol Aging. 2014 Jul; 35(7):1778.e1-8. PMID: 24444806; PMCID: PMC3980008.
    19. Kremen WS, Jak AJ, Panizzon MS, Spoon KM, Franz CE, Thompson WK, Jacobson KC, Vasilopoulos T, Vuoksimaa E, Xian H, Toomey R, Lyons MJ. Early identification and heritability of mild cognitive impairment. Int J Epidemiol. 2014 Apr; 43(2):600-10. PMID: 24370560; PMCID: PMC3997374.
    20. Panizzon MS, Hauger R, Jacobson KC, Eaves LJ, York TP, Prom-Wormley E, Grant MD, Lyons MJ, McKenzie R, Mendoza SP, Xian H, Franz CE, Kremen WS. Genetic and environmental influences of daily and intra-individual variation in testosterone levels in middle-aged men. Psychoneuroendocrinology. 2013 Oct; 38(10):2163-72. PMID: 23639251; PMCID: PMC3775872.
    21. Vuoksimaa E, Panizzon MS, Chen CH, Eyler LT, Fennema-Notestine C, Fiecas MJ, Fischl B, Franz CE, Grant MD, Jak AJ, Lyons MJ, Neale MC, Thompson WK, Tsuang MT, Xian H, Dale AM, Kremen WS. Cognitive reserve moderates the association between hippocampal volume and episodic memory in middle age. Neuropsychologia. 2013 May; 51(6):1124-31. PMID: 23499725; PMCID: PMC3660613.
    22. Panizzon MS, Fennema-Notestine C, Kubarych TS, Chen CH, Eyler LT, Fischl B, Franz CE, Grant MD, Hamza S, Jak A, Jernigan TL, Lyons MJ, Neale MC, Prom-Wormley EC, Seidman L, Tsuang MT, Wu H, Xian H, Dale AM, Kremen WS. Genetic and environmental influences of white and gray matter signal contrast: a new phenotype for imaging genetics? Neuroimage. 2012 Apr 15; 60(3):1686-95. PMID: 22500923; PMCID: PMC3328105.
    23. Panizzon MS, Hauger RL, Eaves LJ, Chen CH, Dale AM, Eyler LT, Fischl B, Fennema-Notestine C, Franz CE, Grant MD, Jacobson KC, Jak AJ, Lyons MJ, Mendoza SP, Neale MC, Prom-Wormley E, Seidman LJ, Tsuang MT, Xian H, Kremen WS. Genetic influences on hippocampal volume differ as a function of testosterone level in middle-aged men. Neuroimage. 2012 Jan 16; 59(2):1123-31. PMID: 21983185; PMCID: PMC3230702.
    24. Kremen WS, Panizzon MS, Xian H, Barch DM, Franz CE, Grant MD, Toomey R, Lyons MJ. Genetic architecture of context processing in late middle age: more than one underlying mechanism. Psychol Aging. 2011 Dec; 26(4):852-63. PMID: 21875218; PMCID: PMC3222785.
    25. Panizzon MS, Lyons MJ, Jacobson KC, Franz CE, Grant MD, Eisen SA, Xian H, Kremen WS. Genetic architecture of learning and delayed recall: a twin study of episodic memory. Neuropsychology. 2011 Jul; 25(4):488-98. PMID: 21463045; PMCID: PMC3125484.
    26. Franz CE, Lyons MJ, O'Brien R, Panizzon MS, Kim K, Bhat R, Grant MD, Toomey R, Eisen S, Xian H, Kremen WS. A 35-year longitudinal assessment of cognition and midlife depression symptoms: the Vietnam Era Twin Study of Aging. Am J Geriatr Psychiatry. 2011 Jun; 19(6):559-70. PMID: 21606899; PMCID: PMC3101375.
    27. Kremen WS, Mai T, Panizzon MS, Franz CE, Blankfeld HM, Xian H, Eisen SA, Tsuang MT, Lyons MJ. A twin study of spatial and non-spatial delayed response performance in middle age. Brain Cogn. 2011 Jun; 76(1):43-51. PMID: 21477911; PMCID: PMC3090345.
    28. Franz CE, O'Brien RC, Hauger RL, Mendoza SP, Panizzon MS, Prom-Wormley E, Eaves LJ, Jacobson K, Lyons MJ, Lupien S, Hellhammer D, Xian H, Kremen WS. Cross-sectional and 35-year longitudinal assessment of salivary cortisol and cognitive functioning: the Vietnam Era twin study of aging. Psychoneuroendocrinology. 2011 Aug; 36(7):1040-52. PMID: 21295410; PMCID: PMC3130089.
    29. Franz CE, York TP, Eaves LJ, Prom-Wormley E, Jacobson KC, Lyons MJ, Grant MD, Xian H, Panizzon MS, Jimenez E, Kremen WS. Adult romantic attachment, negative emotionality, and depressive symptoms in middle aged men: a multivariate genetic analysis. Behav Genet. 2011 Jul; 41(4):488-98. PMID: 21213033; PMCID: PMC3121938.
    30. Fennema-Notestine C, Panizzon MS, Thompson WR, Chen CH, Eyler LT, Fischl B, Franz CE, Grant MD, Jak AJ, Jernigan TL, Lyons MJ, Neale MC, Seidman LJ, Tsuang MT, Xian H, Dale AM, Kremen WS. Presence of ApoE e4 allele associated with thinner frontal cortex in middle age. J Alzheimers Dis. 2011; 26 Suppl 3:49-60. PMID: 21971450; PMCID: PMC3302177.
    31. Kremen WS, Panizzon MS, Neale MC, Fennema-Notestine C, Prom-Wormley E, Eyler LT, Stevens A, Franz CE, Lyons MJ, Grant MD, Jak AJ, Jernigan TL, Xian H, Fischl B, Thermenos HW, Seidman LJ, Tsuang MT, Dale AM. Heritability of brain ventricle volume: converging evidence from inconsistent results. Neurobiol Aging. 2012 Jan; 33(1):1-8. PMID: 20363053; PMCID: PMC3221930.
    32. Franz CE, York TP, Eaves LJ, Mendoza SP, Hauger RL, Hellhammer DH, Jacobson KC, Levine S, Lupien SJ, Lyons MJ, Prom-Wormley E, Xian H, Kremen WS. Genetic and environmental influences on cortisol regulation across days and contexts in middle-aged men. Behav Genet. 2010 Jul; 40(4):467-79. PMID: 20238238; PMCID: PMC2886910.
    33. Panizzon MS, Fennema-Notestine C, Eyler LT, Jernigan TL, Prom-Wormley E, Neale M, Jacobson K, Lyons MJ, Grant MD, Franz CE, Xian H, Tsuang M, Fischl B, Seidman L, Dale A, Kremen WS. Distinct genetic influences on cortical surface area and cortical thickness. Cereb Cortex. 2009 Nov; 19(11):2728-35. PMID: 19299253; PMCID: PMC2758684.
    34. Kremen WS, Jacobson KC, Panizzon MS, Xian H, Eaves LJ, Eisen SA, Tsuang MT, Lyons MJ. Factor structure of planning and problem-solving: a behavioral genetic analysis of the Tower of London task in middle-aged twins. Behav Genet. 2009 Mar; 39(2):133-44. PMID: 19085096; PMCID: PMC2945702.
    35. Kremen WS, Xian H, Jacobson KC, Eaves LJ, Franz CE, Panizzon MS, Eisen SA, Crider A, Lyons MJ. Storage and executive components of working memory: integrating cognitive psychology and behavior genetics in the study of aging. J Gerontol B Psychol Sci Soc Sci. 2008 Mar; 63(2):P84-91. PMID: 18441269; PMCID: PMC2945700.
    36. Kremen WS, Jacobsen KC, Xian H, Eisen SA, Eaves LJ, Tsuang MT, Lyons MJ. Genetics of verbal working memory processes: a twin study of middle-aged men. Neuropsychology. 2007 Sep; 21(5):569-80. PMID: 17784805.
      View in: PubMed
    37. Franz CE, Grant MD, Jacobson KC, Kremen WS, Eisen SA, Xian H, Romeis J, Thompson-Brenner H, Lyons MJ. Genetics of body mass stability and risk for chronic disease: a 28-year longitudinal study. Twin Res Hum Genet. 2007 Aug; 10(4):537-45. PMID: 17708694.
      View in: PubMed
    38. Kremen WS, Lyons MJ, Boake C, Xian H, Jacobson KC, Waterman B, Eisen SA, Goldberg J, Faraone SV, Tsuang MT. A discordant twin study of premorbid cognitive ability in schizophrenia. J Clin Exp Neuropsychol. 2006 Feb; 28(2):208-24. PMID: 16484094.
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    39. Kremen WS, Jacobson KC, Xian H, Eisen SA, Waterman B, Toomey R, Neale MC, Tsuang MT, Lyons MJ. Heritability of word recognition in middle-aged men varies as a function of parental education. Behav Genet. 2005 Jul; 35(4):417-33. PMID: 15971023.
      View in: PubMed