Dr. Marcotte is Professor of Psychiatry at the University of California, San Diego, and Co-Director of the Center for Medicinal Cannabis Research, which has conducted clinical trials of cannabis for almost 20 years, and has an active, ongoing portfolio exploring the effects of cannabinoids (plant-based, synthetic) in various medical/psychiatric conditions. He is currently the principal investigator on studies addressing cannabis for the treatment of pain, and the effects of acute cannabis use on driving performance. He has previously been co-investigator on cannabis studies addressing pain and spasticity in multiple sclerosis. He has been the PI on numerous HIV studies over the years, including projects aimed at examining ART initiation in India, the development of brief screening tools for HAND, and studies examining the impact of HAND on real-world functioning. Dr. Marcotte has developed techniques for assessing the most complex of everyday tasks, driving an automobile, and examined the types of deficits that may predispose an individual to impaired driving abilities. He has also designed tablet-based tools for assessing cognitive impairment. He co-edited the book Neuropsychology of Everyday Functioning.
Dr. Marcotte previously served as the Center Manager of the HIV Neurobehavioral Research Center (1996-2018), and Co-Director of CHARTER (a national multi-site study of the CNS impact of treatments for HIV). Dr. Marcotte has been on the editorial boards of Neuropsychology and the Journal of the International Neuropsychological Society.