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Liu, Lin

TitleAssistant Adjunct Professor
InstitutionUniversity of California San Diego
DepartmentFamily Medicine and Public Health
Address9500 Gilman Drive #0725
La Jolla CA 92093
Phone858-822-5877
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    Dr. Liu’s statistical methodology research includes three areas a) developing efficient methodologies in detecting the difference between dose-response means especially to identify minimum effective dose in dose-response and toxicity studies, b) developing new research methodology and statistical software in analysis of longitudinal HIV viral load data, and c) developing prognostic models in colorectal cancer research. As a collaborative biostatistician, Dr. Liu has worked in the area of cancer, cardiovascular disease, hepatitis C, chronic pain, HIV, infectious disease epidemiology, drug and alcohol abuse, sleep apnea, posttraumatic stress disorder (PTSD), Parkinson’s disease, traumatic brain injury (TBI), psychiatric disorder, telemedicine etc.


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Deering S, Liu L, Zamora T, Hamilton J, Stepnowsky C. CPAP Adherence is Associated With Attentional Improvements in a Group of Primarily Male Patients With Moderate to Severe OSA. J Clin Sleep Med. 2017 Dec 15; 13(12):1423-1428. PMID: 29065955.
      View in: PubMed
    2. Street RL, Liu L, Farber NJ, Chen Y, Calvitti A, Weibel N, Gabuzda MT, Bell K, Gray B, Rick S, Ashfaq S, Agha Z. Keystrokes, Mouse Clicks, and Gazing at the Computer: How Physician Interaction with the EHR Affects Patient Participation. J Gen Intern Med. 2018 Apr; 33(4):423-428. PMID: 29188544.
      View in: PubMed
    3. Groessl EJ, Liu L, Sklar M, Ho SB. HCV Integrated Care: A Randomized Trial to Increase Treatment Initiation and SVR with Direct Acting Antivirals. Int J Hepatol. 2017; 2017:5834182. PMID: 28819570.
      View in: PubMed
    4. Groessl EJ, Liu L, Chang DG, Wetherell JL, Bormann JE, Atkinson JH, Baxi S, Schmalzl L. Yoga for Military Veterans with Chronic Low Back Pain: A Randomized Clinical Trial. Am J Prev Med. 2017 Nov; 53(5):599-608. PMID: 28735778.
      View in: PubMed
    5. Pines HA, Wertheim JO, Liu L, Garfein RS, Little SJ, Karris MY. Concurrency and HIV transmission network characteristics among MSM with recent HIV infection. AIDS. 2016 Nov 28; 30(18):2875-2883. PMID: 27662550.
      View in: PubMed
    6. Herbert MS, Afari N, Liu L, Heppner P, Rutledge T, Williams K, Eraly S, VanBuskirk K, Nguyen C, Bondi M, Atkinson JH, Golshan S, Wetherell JL. Telehealth Versus In-Person Acceptance and Commitment Therapy for Chronic Pain: A Randomized Noninferiority Trial. J Pain. 2017 Feb; 18(2):200-211. PMID: 27838498.
      View in: PubMed
    7. Liu L, Messer K, Baron JA, Lieberman DA, Jacobs ET, Cross AJ, Murphy G, Martinez ME, Gupta S. A prognostic model for advanced colorectal neoplasia recurrence. Cancer Causes Control. 2016 10; 27(10):1175-85. PMID: 27517467.
      View in: PubMed
    8. Groessl EJ, Schmalzl L, Maiya M, Liu L, Goodman D, Chang DG, Wetherell JL, Bormann JE, Atkinson JH, Baxi S. Yoga for veterans with chronic low back pain: Design and methods of a randomized clinical trial. Contemp Clin Trials. 2016 05; 48:110-8. PMID: 27103548.
      View in: PubMed
    9. Farber NJ, Liu L, Chen Y, Calvitti A, Street RL, Zuest D, Bell K, Gabuzda M, Gray B, Ashfaq S, Agha Z. EHR use and patient satisfaction: What we learned. J Fam Pract. 2015 Nov; 64(11):687-96. PMID: 26697540.
      View in: PubMed
    10. Wagner KD, Liu L, Davidson PJ, Cuevas-Mota J, Armenta RF, Garfein RS. Association between non-fatal opioid overdose and encounters with healthcare and criminal justice systems: Identifying opportunities for intervention. Drug Alcohol Depend. 2015 Aug 01; 153:215-20. PMID: 26091751; PMCID: PMC4512661.
    11. Street RL, Liu L, Farber NJ, Chen Y, Calvitti A, Zuest D, Gabuzda MT, Bell K, Gray B, Rick S, Ashfaq S, Agha Z. Provider interaction with the electronic health record: the effects on patient-centered communication in medical encounters. Patient Educ Couns. 2014 Sep; 96(3):315-9. PMID: 24882086; PMCID: PMC4339111.
    12. Pirogovsky E, Schiehser DM, Litvan I, Obtera KM, Burke MM, Lessig SL, Song DD, Liu L, Filoteo JV. The utility of the Mattis Dementia Rating Scale in Parkinson's disease mild cognitive impairment. Parkinsonism Relat Disord. 2014 Jun; 20(6):627-31. PMID: 24709086.
      View in: PubMed
    13. Liu L, Lee CIC and Peng J.Simultaneous Confidence Bounds in Monotone Dose-Response Studies. Journal of Statistical Planning and Inference. 2014; (145):113-124.
    14. Schiehser DM, Ayers CR, Liu L, Lessig S, Song DS, Filoteo JV. Validation of the Modified Fatigue Impact Scale in Parkinson's disease. Parkinsonism Relat Disord. 2013 Mar; 19(3):335-8. PMID: 23246138.
      View in: PubMed
    15. Bormann JE, Liu L, Thorp SR, Lang AJ. Spiritual wellbeing mediates PTSD change in veterans with military-related PTSD. Int J Behav Med. 2012 Dec; 19(4):496-502. PMID: 21874605.
      View in: PubMed
    16. Groessl EJ, Liu L, Sklar M, Tally SR, Kaplan RM, Ganiats TG. Measuring the impact of cataract surgery on generic and vision-specific quality of life. Qual Life Res. 2013 Aug; 22(6):1405-14. PMID: 23015266; PMCID: PMC3578053.
    17. Bhatnagar V, Liu L, Nievergelt CM, Richard E, Brophy VH, Pandey B, Lipkowitz MS, O'Connor DT. Paraoxonase 1 (PON1) C/T-108 association with longitudinal mean arterial blood pressure. Am J Hypertens. 2012 Nov; 25(11):1188-94. PMID: 22854640; PMCID: PMC3515680.
    18. Lindamer LA, Liu L, Sommerfeld DH, Folsom DP, Hawthorne W, Garcia P, Aarons GA, Jeste DV. Predisposing, enabling, and need factors associated with high service use in a public mental health system. Adm Policy Ment Health. 2012 May; 39(3):200-9. PMID: 21533848; PMCID: PMC3288205.
    19. Groessl EJ, Liu L, Ho SB, Kanwal F, Gifford AL, Asch SM. National patterns and predictors of liver biopsy use for management of hepatitis C. J Hepatol. 2012 Aug; 57(2):252-9. PMID: 22521358.
      View in: PubMed
    20. Wetherell JL, Afari N, Rutledge T, Sorrell JT, Stoddard JA, Petkus AJ, Solomon BC, Lehman DH, Liu L, Lang AJ, Atkinson JH. A randomized, controlled trial of acceptance and commitment therapy and cognitive-behavioral therapy for chronic pain. Pain. 2011 Sep; 152(9):2098-107. PMID: 21683527.
      View in: PubMed
    21. Lee J, Aziz H, Liu L, Lipkowitz M, O'Connor DT, Richard E, Brophy V, Wassel CL, Blantz R. ß(1)-adrenergic receptor polymorphisms and response to ß-blockade in the African-American study of kidney disease and hypertension (AASK). Am J Hypertens. 2011 Jun; 24(6):694-700. PMID: 21415838.
      View in: PubMed
    22. Wetherell JL, Afari N, Ayers CR, Stoddard JA, Ruberg J, Sorrell JT, Liu L, Petkus AJ, Thorp SR, Kraft A, Patterson TL. Acceptance and Commitment Therapy for generalized anxiety disorder in older adults: a preliminary report. Behav Ther. 2011 Mar; 42(1):127-34. PMID: 21292059; PMCID: PMC3496779.
    23. Lyden P, Raman R, Liu L, Emr M, Warren M, Marler J. National Institutes of Health Stroke Scale certification is reliable across multiple venues. Stroke. 2009 Jul; 40(7):2507-11. PMID: 19520998; PMCID: PMC2726278.
    24. Vaida F and Liu L.Fast Implementation for Normal Mixed Effects Models with Censored Response. Journal of Computational and Graphical Statistics. 2009; 4(18):797-817.
    25. Liu L, May S, Richman DD, Hecht FM, Markowitz M, Daar ES, Routy JP, Margolick JB, Collier AC, Woelk CH, Little SJ, Smith DM. Comparison of algorithms that interpret genotypic HIV-1 drug resistance to determine the prevalence of transmitted drug resistance. AIDS. 2008 Apr 23; 22(7):835-9. PMID: 18427201; PMCID: PMC2716722.
    26. Koelsch KK, Liu L, Haubrich R, May S, Havlir D, Günthard HF, Ignacio CC, Campos-Soto P, Little SJ, Shafer R, Robbins GK, D'Aquila RT, Kawano Y, Young K, Dao P, Spina CA, Richman DD, Wong JK. Dynamics of total, linear nonintegrated, and integrated HIV-1 DNA in vivo and in vitro. J Infect Dis. 2008 Feb 01; 197(3):411-9. PMID: 18248304.
      View in: PubMed
    27. Bashey A, Donohue M, Liu L, Medina B, Corringham S, Ihasz A, Carrier E, Castro JE, Holman PR, Xu R, Law P, Ball ED, Lane TA. Peripheral blood progenitor cell mobilization with intermediate-dose cyclophosphamide, sequential granulocyte-macrophage-colony-stimulating factor and granulocyte-colony-stimulating factor, and scheduled commencement of leukapheresis in 225 patients undergoing autologous transplantation. Transfusion. 2007 Nov; 47(11):2153-60. PMID: 17958545.
      View in: PubMed
    28. Goicoechea M, Smith DM, Liu L, May S, Tenorio AR, Ignacio CC, Landay A, Haubrich R. Determinants of CD4+ T cell recovery during suppressive antiretroviral therapy: association of immune activation, T cell maturation markers, and cellular HIV-1 DNA. J Infect Dis. 2006 Jul 01; 194(1):29-37. PMID: 16741879.
      View in: PubMed
    29. Lee CC, Peng J and Liu L .Statistical Inference for the Difference between the Best Treatment Mean and a Control Mean. Journal of the American Statistical Association. 2006; (101):1050-1058.
    30. Bashey A, Liu L, Ihasz A, Medina B, Corringham S, Keese K, Carrier E, Castro JE, Holman P, Lane TA, Hassidim K, Ball ED. Non-anthracycline based remission induction therapy for newly diagnosed patients with acute myeloid leukemia aged 60 or older. Leuk Res. 2006 Apr; 30(4):503-6. PMID: 16303178.
      View in: PubMed
    31. Lyden P, Raman R, Liu L, Grotta J, Broderick J, Olson S, Shaw S, Spilker J, Meyer B, Emr M, Warren M, Marler J. NIHSS training and certification using a new digital video disk is reliable. Stroke. 2005 Nov; 36(11):2446-9. PMID: 16224093.
      View in: PubMed
    32. Liu L, Lee CC and Peng J.Max-min Multiple Comparison Procedure for MonotoneDose-Response Curves. Journal of Statistical Planning and Inference. 2002; (107):133-141.