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Fotios Asimakopoulos

Title(s)Associate Professor In Residence, Medicine
SchoolHealth Sciences
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    Collapse Biography 
    Collapse Education and Training
    University of Cambridge, Cambridge UKMD PhD01/1997Medicine, Hematology
    Hebrew University of Jerusalem, Jerusalem IsraelGolda Meir Fellow06/1999Hematology
    BWH, Harvard Medical School, Boston MAResidency06/2001Internal Medicine
    Memorial Sloan-Kettering Cancer Center, New York, NYFellowship06/2009Medical Oncology

    Collapse Overview 

    Collapse ORNG Applications 
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Dhakal B, Pagenkopf A, Mushtaq MU, Cunningham AM, Flietner E, Morrow Z, Papadas A, Hope C, Leith C, Hematti P, Hari P, Callander NS, Asimakopoulos F. Versican proteolysis predicts immune effector infiltration and post-transplant survival in myeloma. Leuk Lymphoma. 2019 Oct; 60(10):2558-2562. PMID: 30845856.
      View in: PubMed
    2. Asimakopoulos F. TIGIT checkpoint inhibition for myeloma. Blood. 2018 10 18; 132(16):1629-1630. PMID: 30337318.
      View in: PubMed
    3. Mushtaq MU, Papadas A, Pagenkopf A, Flietner E, Morrow Z, Chaudhary SG, Asimakopoulos F. Tumor matrix remodeling and novel immunotherapies: the promise of matrix-derived immune biomarkers. J Immunother Cancer. 2018 07 03; 6(1):65. PMID: 29970158.
      View in: PubMed
    4. Dhakal B, Szabo A, Chhabra S, Hamadani M, D'Souza A, Usmani SZ, Sieracki R, Gyawali B, Jackson JL, Asimakopoulos F, Hari PN. Autologous Transplantation for Newly Diagnosed Multiple Myeloma in the Era of Novel Agent Induction: A Systematic Review and Meta-analysis. JAMA Oncol. 2018 Mar 01; 4(3):343-350. PMID: 29302684.
      View in: PubMed
    5. Papadas A, Asimakopoulos F. Mechanisms of Resistance in Multiple Myeloma. Handb Exp Pharmacol. 2018; 249:251-288. PMID: 28315070.
      View in: PubMed
    6. Huynh M, Pak C, Markovina S, Callander NS, Chng KS, Wuerzberger-Davis SM, Bakshi DD, Kink JA, Hematti P, Hope C, Asimakopoulos F, Rui L, Miyamoto S. Hyaluronan and proteoglycan link protein 1 (HAPLN1) activates bortezomib-resistant NF-?B activity and increases drug resistance in multiple myeloma. J Biol Chem. 2018 02 16; 293(7):2452-2465. PMID: 29279332.
      View in: PubMed
    7. Asimakopoulos F, Hope C, Johnson MG, Pagenkopf A, Gromek K, Nagel B. Extracellular matrix and the myeloid-in-myeloma compartment: balancing tolerogenic and immunogenic inflammation in the myeloma niche. J Leukoc Biol. 2017 08; 102(2):265-275. PMID: 28254840.
      View in: PubMed
    8. Hope C, Foulcer S, Jagodinsky J, Chen SX, Jensen JL, Patel S, Leith C, Maroulakou I, Callander N, Miyamoto S, Hematti P, Apte SS, Asimakopoulos F. Immunoregulatory roles of versican proteolysis in the myeloma microenvironment. Blood. 2016 08 04; 128(5):680-5. PMID: 27259980.
      View in: PubMed
    9. Jensen JL, Hope C, Asimakopoulos F. Deploying myeloid cells against myeloma. Oncoimmunology. 2016 Mar; 5(3):e1090076. PMID: 27141348.
      View in: PubMed
    10. Gupta A, Place M, Goldstein S, Sarkar D, Zhou S, Potamousis K, Kim J, Flanagan C, Li Y, Newton MA, Callander NS, Hematti P, Bresnick EH, Ma J, Asimakopoulos F, Schwartz DC. Single-molecule analysis reveals widespread structural variation in multiple myeloma. Proc Natl Acad Sci U S A. 2015 Jun 23; 112(25):7689-94. PMID: 26056298.
      View in: PubMed
    11. Pak C, Callander NS, Young EW, Titz B, Kim K, Saha S, Chng K, Asimakopoulos F, Beebe DJ, Miyamoto S. MicroC(3): an ex vivo microfluidic cis-coculture assay to test chemosensitivity and resistance of patient multiple myeloma cells. Integr Biol (Camb). 2015 Jun; 7(6):643-54. PMID: 25998180.
      View in: PubMed
    12. Jensen JL, Rakhmilevich A, Heninger E, Broman AT, Hope C, Phan F, Miyamoto S, Maroulakou I, Callander N, Hematti P, Chesi M, Bergsagel PL, Sondel P, Asimakopoulos F. Tumoricidal Effects of Macrophage-Activating Immunotherapy in a Murine Model of Relapsed/Refractory Multiple Myeloma. Cancer Immunol Res. 2015 Aug; 3(8):881-90. PMID: 25941352.
      View in: PubMed
    13. Callander N, Markovina S, Eickhoff J, Hutson P, Campbell T, Hematti P, Go R, Hegeman R, Longo W, Williams E, Asimakopoulos F, Miyamoto S. Acetyl-L-carnitine (ALCAR) for the prevention of chemotherapy-induced peripheral neuropathy in patients with relapsed or refractory multiple myeloma treated with bortezomib, doxorubicin and low-dose dexamethasone: a study from the Wisconsin Oncology Network. Cancer Chemother Pharmacol. 2014 Oct; 74(4):875-82. PMID: 25168296.
      View in: PubMed
    14. Hope C, Ollar SJ, Heninger E, Hebron E, Jensen JL, Kim J, Maroulakou I, Miyamoto S, Leith C, Yang DT, Callander N, Hematti P, Chesi M, Bergsagel PL, Asimakopoulos F. TPL2 kinase regulates the inflammatory milieu of the myeloma niche. Blood. 2014 May 22; 123(21):3305-15. PMID: 24723682.
      View in: PubMed
    15. Asimakopoulos F, Kim J, Denu RA, Hope C, Jensen JL, Ollar SJ, Hebron E, Flanagan C, Callander N, Hematti P. Macrophages in multiple myeloma: emerging concepts and therapeutic implications. Leuk Lymphoma. 2013 Oct; 54(10):2112-21. PMID: 23432691.
      View in: PubMed
    16. Hebron E, Hope C, Kim J, Jensen JL, Flanagan C, Bhatia N, Maroulakou I, Mitsiades C, Miyamoto S, Callander N, Hematti P, Asimakopoulos F. MAP3K8 kinase regulates myeloma growth by cell-autonomous and non-autonomous mechanisms involving myeloma-associated monocytes/macrophages. Br J Haematol. 2013 Mar; 160(6):779-84. PMID: 23252623.
      View in: PubMed
    17. Kim J, Denu RA, Dollar BA, Escalante LE, Kuether JP, Callander NS, Asimakopoulos F, Hematti P. Macrophages and mesenchymal stromal cells support survival and proliferation of multiple myeloma cells. Br J Haematol. 2012 Aug; 158(3):336-46. PMID: 22583117.
      View in: PubMed