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Hang Yao

Title(s)Project Scientist, Pediatrics
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. China's Malaria R&D Innovations: A Scoping Review from 2013-2023. China CDC Wkly. 2025 May 02; 7(18):635-643. Wang S, Ding W, Lu S, Li L, Qian F, Chen C, Liu L, Cai Y, Liu X, Perez S, Frutos R, Yao H, Zhou Y, Ye C, Wu D, Li S, Kwete XJ, Sui Y, Wang D. PMID: 40376501; PMCID: PMC12075444.
      View in: PubMed   Mentions:
    2. Evaluating Bacillus Calmette-Guérin Polysaccharide Nucleic Acid as an Adjuvant for Influenza Vaccines in Mice. Influenza Other Respir Viruses. 2025 05; 19(5):e70118. Yan S, Yang F, Ji J, Lin X, Wang P, Wu H, Cheng L, Liu F, Wu N, Yao H, Wu WSJ, Wu H. PMID: 40338109; PMCID: PMC12058303.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    3. A human-infecting H10N5 avian influenza virus: Clinical features, virus reassortment, receptor-binding affinity, and possible transmission routes. J Infect. 2025 Apr; 90(4):106456. Yang J, Zheng S, Sun J, Wu H, Zhang D, Wang Y, Tian T, Zhu L, Wu Z, Li L, Gao GF, Bi Y, Yao H. PMID: 40049527.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    4. Buprenorphine and methadone differentially alter early brain development in human cortical organoids. Neuropharmacology. 2023 11 15; 239:109683. Yao H, Hu D, Wang J, Wu W, Zhao HH, Wang L, Gleeson J, Haddad GG. PMID: 37543137; PMCID: PMC11771310.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    5. Preventive and therapeutic benefits of nelfinavir in rhesus macaques and human beings infected with SARS-CoV-2. Signal Transduct Target Ther. 2023 04 24; 8(1):169. Xu Z, Shi D, Han JB, Ling Y, Jiang X, Lu X, Li C, Gong L, Ge G, Zhang Y, Zang Y, Song TZ, Feng XL, Tian RR, Ji J, Zhu M, Wu N, Wu C, Wang Z, Xu Y, Peng C, Zheng M, Yang J, Du F, Wu J, Wang P, Shen J, Zhang J, Zheng YT, Yao H, Zhu W. PMID: 37095086; PMCID: PMC10123561.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    6. Neuronal hyperexcitability and ion channel dysfunction in CDKL5-deficiency patient iPSC-derived cortical organoids. Neurobiol Dis. 2022 Nov; 174:105882. Wu W, Yao H, Negraes PD, Wang J, Trujillo CA, de Souza JS, Muotri AR, Haddad GG. PMID: 36202289.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    7. The viral distribution and pathological characteristics of BALB/c mice infected with highly pathogenic Influenza H7N9 virus. Virol J. 2021 11 29; 18(1):237. Wu XX, Tang SJ, Yao SH, Zhou YQ, Xiao LL, Cheng LF, Liu FM, Wu NP, Yao HP, Li LJ. PMID: 34844617; PMCID: PMC8628282.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    8. The low contagiousness and new A958D mutation of SARS-CoV-2 in children: An observational cohort study. Int J Infect Dis. 2021 Oct; 111:347-353. Chen Y, Yao H, Fu J, Shu Q, Chen Z, Wu N, Ye S, Wang W, Ni Y, Shang S, Li W, Zheng J, Li S, Hong L, Zhang Q, Xu W, Chen J, Fan L, Cang X, Wang J, Lu X, Cao Q. PMID: 34454120; PMCID: PMC8384730.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    9. Duocarmycin-based antibody-drug conjugates as an emerging biotherapeutic entity for targeted cancer therapy: Pharmaceutical strategy and clinical progress. Drug Discov Today. 2021 08; 26(8):1857-1874. Yao HP, Zhao H, Hudson R, Tong XM, Wang MH. PMID: 34224904.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimals
    10. Altered network and rescue of human neurons derived from individuals with early-onset genetic epilepsy. Mol Psychiatry. 2021 11; 26(11):7047-7068. Negraes PD, Trujillo CA, Yu NK, Wu W, Yao H, Liang N, Lautz JD, Kwok E, McClatchy D, Diedrich J, de Bartolome SM, Truong J, Szeto R, Tran T, Herai RH, Smith SEP, Haddad GG, Yates JR, Muotri AR. PMID: 33888873; PMCID: PMC8531162.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    11. Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection. Cell Res. 2021 01; 31(1):25-36. Yao H, Sun Y, Deng YQ, Wang N, Tan Y, Zhang NN, Li XF, Kong C, Xu YP, Chen Q, Cao TS, Zhao H, Yan X, Cao L, Lv Z, Zhu D, Feng R, Wu N, Zhang W, Hu Y, Chen K, Zhang RR, Lv Q, Sun S, Zhou Y, Yan R, Yang G, Sun X, Liu C, Lu X, Cheng L, Qiu H, Huang XY, Weng T, Shi D, Jiang W, Shao J, Wang L, Zhang J, Jiang T, Lang G, Qin CF, Li L, Wang X. PMID: 33262452; PMCID: PMC7705443.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    12. Methadone Suppresses Neuronal Function and Maturation in Human Cortical Organoids. Front Neurosci. 2020; 14:593248. Wu W, Yao H, Dwivedi I, Negraes PD, Zhao HW, Wang J, Trujillo CA, Muotri AR, Haddad GG. PMID: 33328864; PMCID: PMC7719724.
      View in: PubMed   Mentions: 10  
    13. Methadone interrupts neural growth and function in human cortical organoids. Stem Cell Res. 2020 12; 49:102065. Yao H, Wu W, Cerf I, Zhao HW, Wang J, Negraes PD, Muotri AR, Haddad GG. PMID: 33137567.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    14. Antibody-drug conjugates targeting RON receptor tyrosine kinase as a novel strategy for treatment of triple-negative breast cancer. Drug Discov Today. 2020 07; 25(7):1160-1173. Yao HP, Suthe SR, Hudson R, Wang MH. PMID: 32479905.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    15. RON receptor tyrosine kinase in pancreatic ductal adenocarcinoma: Pathogenic mechanism in malignancy and pharmaceutical target for therapy. Biochim Biophys Acta Rev Cancer. 2020 04; 1873(2):188360. Yao HP, Hudson R, Wang MH. PMID: 32234337.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    16. Endogenous authentic OCT4A proteins directly regulate FOS/AP-1 transcription in somatic cancer cells. Cell Death Dis. 2018 05 22; 9(6):585. Zhou Y, Chen X, Kang B, She S, Zhang X, Chen C, Li W, Chen W, Dan S, Pan X, Liu X, He J, Zhao Q, Zhu C, Peng L, Wang H, Yao H, Cao H, Li L, Herlyn M, Wang YJ. PMID: 29789579; PMCID: PMC5964179.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    17. Intracellular pH Regulation in iPSCs-derived Astrocytes from Subjects with Chronic Mountain Sickness. Neuroscience. 2018 04 01; 375:25-33. Yao H, Zhao H, Wang J, Haddad GG. PMID: 29438800; PMCID: PMC5851838.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    18. Down-regulation of Inwardly Rectifying K+ Currents in Astrocytes Derived from Patients with Monge's Disease. Neuroscience. 2018 03 15; 374:70-79. Wu W, Yao H, Zhao HW, Wang J, Haddad GG. PMID: 29355592.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    19. Mitochondrial dysfunction in iPSC-derived neurons of subjects with chronic mountain sickness. J Appl Physiol (1985). 2018 09 01; 125(3):832-840. Zhao H, Perkins G, Yao H, Callacondo D, Appenzeller O, Ellisman M, La Spada AR, Haddad GG. PMID: 29357502; PMCID: PMC6734077.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    20. The Na+/HCO3- co-transporter is protective during ischemia in astrocytes. Neuroscience. 2016 Dec 17; 339:329-337. Yao H, Azad P, Zhao HW, Wang J, Poulsen O, Freitas BC, Muotri AR, Haddad GG. PMID: 27717805; PMCID: PMC5118130.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    21. Akt‑mediated phosphorylation of Oct4 is associated with the proliferation of stem‑like cancer cells. Oncol Rep. 2015 Apr; 33(4):1621-9. Zhao QW, Zhou YW, Li WX, Kang B, Zhang XQ, Yang Y, Cheng J, Yin SY, Tong Y, He JQ, Yao HP, Zheng M, Wang YJ. PMID: 25625591; PMCID: PMC4358081.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    22. Prevention of BMS-777607-induced polyploidy/senescence by mTOR inhibitor AZD8055 sensitizes breast cancer cells to cytotoxic chemotherapeutics. Mol Oncol. 2014 May; 8(3):469-82. Sharma S, Yao HP, Zhou YQ, Zhou J, Zhang R, Wang MH. PMID: 24444656; PMCID: PMC5528636.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    23. Chemokine receptor-like 2 is involved in ischemic brain injury. J Exp Stroke Transl Med. 2013 Feb 17; 6:1-6. Douglas RM, Chen AH, Iniguez A, Wang J, Fu Z, Powell FL, Haddad GG, Yao H. PMID: 23847708; PMCID: PMC3705577.
      View in: PubMed   Mentions: 5  
    24. Intracellular MHC class II molecules promote TLR-triggered innate immune responses by maintaining activation of the kinase Btk. Nat Immunol. 2011 May; 12(5):416-24. Liu X, Zhan Z, Li D, Xu L, Ma F, Zhang P, Yao H, Cao X. PMID: 21441935.
      View in: PubMed   Mentions: 140     Fields:    Translation:AnimalsCells
    25. Hematopoietic stem cell transplantation protects mice from lethal stroke. Exp Neurol. 2010 Oct; 225(2):284-93. Felfly H, Muotri A, Yao H, Haddad GG. PMID: 20547154; PMCID: PMC2963425.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    26. Brucea javanica oil induces apoptosis in T24 bladder cancer cells via upregulation of caspase-3, caspase-9, and inhibition of NF-kappaB and COX-2 expressions. Am J Chin Med. 2010; 38(3):613-24. Lou GG, Yao HP, Xie LP. PMID: 20503476.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    27. Insulin/PI3K signaling protects dentate neurons from oxygen-glucose deprivation in organotypic slice cultures. J Neurochem. 2010 Jan; 112(2):377-88. Sun X, Yao H, Douglas RM, Gu XQ, Wang J, Haddad GG. PMID: 19860861; PMCID: PMC4524356.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    28. DIDS protects against neuronal injury by blocking Toll-like receptor 2 activated-mechanisms. J Neurochem. 2009 Feb; 108(3):835-46. Yao H, Felfly H, Wang J, Zhou D, Haddad GG. PMID: 19077053; PMCID: PMC2782475.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    29. Modulation of hSlo BK current inactivation by fatty acid esters of CoA. J Neurochem. 2008 Mar; 104(5):1394-403. Sun X, Yao H, Zhou D, Gu X, Haddad GG. PMID: 18005338.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    30. Role of transporters and ion channels in neuronal injury under hypoxia. Am J Physiol Regul Integr Comp Physiol. 2008 Feb; 294(2):R451-7. Xue J, Zhou D, Yao H, Haddad GG. PMID: 17977915.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    31. Cell death in an ischemic infarct rim model. J Neurochem. 2007 Nov; 103(4):1644-53. Yao H, Sun X, Gu X, Wang J, Haddad GG. PMID: 17727626.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    32. Novel functional interaction between Na+/H+ exchanger 1 and tyrosine phosphatase SHP-2. Am J Physiol Regul Integr Comp Physiol. 2007 Jun; 292(6):R2406-16. Xue J, Zhou D, Yao H, Gavrialov O, McConnell MJ, Gelb BD, Haddad GG. PMID: 17289818.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    33. Factors influencing cell fate in the infarct rim. J Neurochem. 2007 Mar; 100(5):1224-33. Yao H, Shu Y, Wang J, Brinkman BC, Haddad GG. PMID: 17217421.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    34. Chronic high-inspired CO2 decreases excitability of mouse hippocampal neurons. J Neurophysiol. 2007 Feb; 97(2):1833-8. Gu XQ, Kanaan A, Yao H, Haddad GG. PMID: 17202241.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    35. [Effect of Triptolide on TNFalpha-induced activation of NF-kappaB and expression of COX-2 and iNOS in human rheumatoid arthritis synovial fibroblasts]. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2004 03; 33(2):160-5. Shao XT, Feng L, Yao HP, Sun WJ, Zhang LH. PMID: 15067740.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    36. [Enhancement by FK506 of triptolide-induced inhibition of expression of COX-2 and iNOS in human rheumatoid arthritis synovial fibroblasts]. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 2003 Mar; 35(3):277-82. Yao HP, Shao XT, Sun WJ, Shao CS, Zhang LH. PMID: 12621554.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
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