Our site may be slower due to heavy traffic from automated "bots" and AI crawlers. We're working to fix this.

Yang Xu

Title(s)Emeritus Professor, Molecular Biology
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
vCardDownload vCard

    Collapse Research 
    Collapse research activities and funding
    Regulation of Nanog in DNA damage response, development and tumorigenesis
    NIH R01CA124834Sep 10, 2007 - Jul 31, 2011
    Role: Principal Investigator
    Genetic analysis of p53 stability and activity
    NIH R01CA094254Jul 1, 2001 - Dec 31, 2013
    Role: Principal Investigator
    FUNCTIONAL STUDIES OF IMMUNOGLOBULIN KAPPA ENHANCERS
    NIH R01AI044838Aug 1, 2000 - May 31, 2006
    Role: Principal Investigator
    Mechanisms of pathogenesis in ataxia-telanglectasia
    NIH R01CA077563Dec 1, 1998 - Jun 30, 2007
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. STAT3 drives the expression of HIF1alpha in cancer cells through a novel super-enhancer. Biochem Biophys Res Commun. 2024 11 26; 735:150483. Dai Y, Ying Y, Zhu G, Xu Y, Ji K. PMID: 39098275.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    2. hESC-derived immune suppressive dendritic cells induce immune tolerance of parental hESC-derived allografts. EBioMedicine. 2020 Dec; 62:103120. Todorova D, Zhang Y, Chen Q, Liu J, He J, Fu X, Xu Y. PMID: 33242828; PMCID: PMC7695963.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    3. Repair of acute liver damage with immune evasive hESC derived hepato-blasts. Stem Cell Res. 2020 12; 49:102010. Liu J, Pan T, Chen Y, Liu Y, Yang F, Chen Q, Abbas N, Zhong M, Zhang Q, Xu Y, Li YX. PMID: 33011360.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    4. CAS9 is a genome mutator by directly disrupting DNA-PK dependent DNA repair pathway. Protein Cell. 2020 05; 11(5):352-365. Xu S, Kim J, Tang Q, Chen Q, Liu J, Xu Y, Fu X. PMID: 32170574; PMCID: PMC7196600.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    5. MTR4 drives liver tumorigenesis by promoting cancer metabolic switch through alternative splicing. Nat Commun. 2020 02 05; 11(1):708. Yu L, Kim J, Jiang L, Feng B, Ying Y, Ji KY, Tang Q, Chen W, Mai T, Dou W, Zhou J, Xiang LY, He YF, Yang D, Li Q, Fu X, Xu Y. PMID: 32024842; PMCID: PMC7002374.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    6. A miRNA-HERC4 pathway promotes breast tumorigenesis by inactivating tumor suppressor LATS1. Protein Cell. 2019 08; 10(8):595-605. Xu Y, Ji K, Wu M, Hao B, Yao KT, Xu Y. PMID: 30710319; PMCID: PMC6626598.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    7. Wild-Type p53 Promotes Cancer Metabolic Switch by Inducing PUMA-Dependent Suppression of Oxidative Phosphorylation. Cancer Cell. 2019 02 11; 35(2):191-203.e8. Kim J, Yu L, Chen W, Xu Y, Wu M, Todorova D, Tang Q, Feng B, Jiang L, He J, Chen G, Fu X, Xu Y. PMID: 30712844.
      View in: PubMed   Mentions: 114     Fields:    Translation:HumansAnimalsCells
    8. An Immune System-Modified Rat Model for Human Stem Cell Transplantation Research. Stem Cell Reports. 2018 08 14; 11(2):514-521. Yang X, Zhou J, He J, Liu J, Wang H, Liu Y, Jiang T, Zhang Q, Fu X, Xu Y. PMID: 29983387; PMCID: PMC6092637.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    9. Artemisitene suppresses tumorigenesis by inducing DNA damage through deregulating c-Myc-topoisomerase pathway. Oncogene. 2018 09; 37(37):5079-5087. Chen J, Li W, Cui K, Ji K, Xu S, Xu Y. PMID: 29795406.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    10. DNA repair mechanisms in embryonic stem cells. Cell Mol Life Sci. 2017 02; 74(3):487-493. Fu X, Cui K, Yi Q, Yu L, Xu Y. PMID: 27614628; PMCID: PMC11107665.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    11. Obacunone activates the Nrf2-dependent antioxidant responses. Protein Cell. 2016 09; 7(9):684-8. Xu S, Chen W, Xie Q, Xu Y. PMID: 27530494; PMCID: PMC5003787.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    12. Humanized Mice Reveal Differential Immunogenicity of Cells Derived from Autologous Induced Pluripotent Stem Cells. Cell Stem Cell. 2015 Sep 03; 17(3):353-9. Zhao T, Zhang ZN, Westenskow PD, Todorova D, Hu Z, Lin T, Rong Z, Kim J, He J, Wang M, Clegg DO, Yang YG, Zhang K, Friedlander M, Xu Y. PMID: 26299572; PMCID: PMC9721102.
      View in: PubMed   Mentions: 127     Fields:    Translation:HumansAnimalsCells
    13. Immunosuppressive activity of pogostone on T cells: Blocking proliferation via S phase arrest. Int Immunopharmacol. 2015 Jun; 26(2):328-37. Su JY, Luo X, Zhang XJ, Deng XL, Su ZR, Zhou L, Li SS, Dai Z, Xu Y, Lai XP. PMID: 25912345.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    14. Stemness factor Sall4 is required for DNA damage response in embryonic stem cells. J Cell Biol. 2015 Mar 02; 208(5):513-20. Xiong J, Todorova D, Su NY, Kim J, Lee PJ, Shen Z, Briggs SP, Xu Y. PMID: 25733712; PMCID: PMC4347641.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    15. An effective approach to prevent immune rejection of human ESC-derived allografts. Cell Stem Cell. 2014 Jan 02; 14(1):121-30. Rong Z, Wang M, Hu Z, Stradner M, Zhu S, Kong H, Yi H, Goldrath A, Yang YG, Xu Y, Fu X. PMID: 24388175; PMCID: PMC4023958.
      View in: PubMed   Mentions: 123     Fields:    Translation:HumansAnimalsCells
    16. Induction of genetic instability by gain-of-function p53 cancer mutants. Oncogene. 2008 Jun 05; 27(25):3501-7. Xu Y. PMID: 18223686.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    17. DNA damage: a trigger of innate immunity but a requirement for adaptive immune homeostasis. Nat Rev Immunol. 2006 Apr; 6(4):261-70. Xu Y. PMID: 16498454.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    18. A new role for p53 in maintaining genetic stability in embryonic stem cells. Cell Cycle. 2005 Mar; 4(3):363-4. Xu Y. PMID: 15701975.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    19. Regulation of p53 responses by post-translational modifications. Cell Death Differ. 2003 Apr; 10(4):400-3. Xu Y. PMID: 12719715.
      View in: PubMed   Mentions: 100     Fields:    Translation:HumansAnimalsCells
    20. Involvement of p53 and p21 in cellular defects and tumorigenesis in Atm-/- mice. Mol Cell Biol. 1998 Jul; 18(7):4385-90. Xu Y, Yang EM, Brugarolas J, Jacks T, Baltimore D. PMID: 9632822; PMCID: PMC109022.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimals
    Yang's Networks
    Concepts (172)
    Derived automatically from this person's publications.
    Explore
    _
    Co-Authors (3)
    People in Profiles who have published with this person.
    Explore
    _
    Similar People (60)
    People who share similar concepts with this person.
    Explore
    _
    Same Department
    Search Department
    _

    UCSD Profiles is managed by the UC San Diego Altman Clinical and Translational Research Institute (ACTRI).
    This site is running Profiles RNS version UCSF-v3.1.0-16-gff1bd585 on PROFILES-PWEB04. We use cookies to operate our website. We also use cookies to analyze our site’s performance and improve your experience on our site. For more information about how we use cookies, please see our Website Terms of Use.

    Copyright © The Regents of the University of California