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    Raul Coimbra

    TitleProfessor
    SchoolUniversity of California, San Diego
    DepartmentSurgery
    Address200 W. Arbor Drive #8896
    CA San Diego 92103
    Phone619-543-7107
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      Dr. Raul Coimbra is the Surgeon-in-Chief of the UC San Diego Medical Center in Hillcrest, Executive Vice-Chairman of the Department of Surgery, Chief of the Division of Trauma, Surgical Critical Care, Burns and Acute Care Surgery, as well as the Director of the Level-1 Trauma Center at UC San Diego Health System.

      Dr. Coimbra has played a significant role in building our region's first Level-1 Trauma Center into one of the top programs in the nation, as well as a model for trauma centers around the world.

      He is President of the Board of Directors for the World Coalition for Trauma Care, as well as a member of the Global Alliance for the Care of the Injured with the Division of Trauma and Injury Prevention of the World Health Organization. He is the Chairman of the Trauma Registry and Data Committee for the World Health Organization.

      In addition, Dr. Coimbra is an active member of the American College of Surgeons Committee on Trauma, as well as Chair of the Regional Committees of the American College of Surgeons Committee on Trauma. He has been appointed to a three-year term as Recorder and Scientific Chairman of the American Association for the Surgery of Trauma. He is also the Chairman of the San Diego County Trauma Medical Audit Committee, providing leadership to the Trauma System in research, education, clinical practice and quality improvement.

      His vision and dedication have resulted in the opening of a new, state-of-the art trauma resuscitation unit at UC San Diego's Medical Center in Hillcrest, which has improved the efficiency for surgeons and addresses the continued growth of the trauma program and commitment of the community it serves in southwest San Diego.


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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Dang X, Zeng X, Coimbra R, Eliceiri BP, Baird A. Counter regulation of ECRG4 gene expression by hypermethylation-dependent inhibition and the Sp1 transcription factor-dependent stimulation of the c2orf40 promoter. Gene. 2017 Sep 01. PMID: 28870864.
        View in: PubMed
      2. Kojima M, Gimenes-Junior JA, Chan TW, Eliceiri BP, Baird A, Costantini TW, Coimbra R. Exosomes in postshock mesenteric lymph are key mediators of acute lung injury triggering the macrophage activation via Toll-like receptor 4. FASEB J. 2017 Aug 29. PMID: 28855278.
        View in: PubMed
      3. Coccolini F, Montori G, Catena F, Kluger Y, Biffl W, Moore EE, Reva V, Bing C, Bala M, Fugazzola P, Bahouth H, Marzi I, Velmahos G, Ivatury R, Soreide K, Horer T, Ten Broek R, Pereira BM, Fraga GP, Inaba K, Kashuk J, Parry N, Masiakos PT, Mylonas KS, Kirkpatrick A, Abu-Zidan F, Gomes CA, Benatti SV, Naidoo N, Salvetti F, Maccatrozzo S, Agnoletti V, Gamberini E, Solaini L, Costanzo A, Celotti A, Tomasoni M, Khokha V, Arvieux C, Napolitano L, Handolin L, Pisano M, Magnone S, Spain DA, de Moya M, Davis KA, De Angelis N, Leppaniemi A, Ferrada P, Latifi R, Navarro DC, Otomo Y, Coimbra R, Maier RV, Moore F, Rizoli S, Sakakushev B, Galante JM, Chiara O, Cimbanassi S, Mefire AC, Weber D, Ceresoli M, Peitzman AB, Wehlie L, Sartelli M, Di Saverio S, Ansaloni L. Splenic trauma: WSES classification and guidelines for adult and pediatric patients. World J Emerg Surg. 2017; 12:40. PMID: 28828034.
        View in: PubMed
      4. Coccolini F, Montori G, Ceresoli M, Catena F, Moore EE, Ivatury R, Biffl W, Peitzman A, Coimbra R, Rizoli S, Kluger Y, Abu-Zidan FM, Sartelli M, De Moya M, Velmahos G, Fraga GP, Pereira BM, Leppaniemi A, Boermeester MA, Kirkpatrick AW, Maier R, Bala M, Sakakushev B, Khokha V, Malbrain M, Agnoletti V, Martin-Loeches I, Sugrue M, Di Saverio S, Griffiths E, Soreide K, Mazuski JE, May AK, Montravers P, Melotti RM, Pisano M, Salvetti F, Marchesi G, Valetti TM, Scalea T, Chiara O, Kashuk JL, Ansaloni L. The role of open abdomen in non-trauma patient: WSES Consensus Paper. World J Emerg Surg. 2017; 12:39. PMID: 28814969.
        View in: PubMed
      5. Birindelli A, Sartelli M, Di Saverio S, Coccolini F, Ansaloni L, van Ramshorst GH, Campanelli G, Khokha V, Moore EE, Peitzman A, Velmahos G, Moore FA, Leppaniemi A, Burlew CC, Biffl WL, Koike K, Kluger Y, Fraga GP, Ordonez CA, Novello M, Agresta F, Sakakushev B, Gerych I, Wani I, Kelly MD, Gomes CA, Faro MP, Tarasconi A, Demetrashvili Z, Lee JG, Vettoretto N, Guercioni G, Persiani R, Tranà C, Cui Y, Kok KYY, Ghnnam WM, Abbas AE, Sato N, Marwah S, Rangarajan M, Ben-Ishay O, Adesunkanmi ARK, Lohse HAS, Kenig J, Mandalà S, Coimbra R, Bhangu A, Suggett N, Biondi A, Portolani N, Baiocchi G, Kirkpatrick AW, Scibé R, Sugrue M, Chiara O, Catena F. 2017 update of the WSES guidelines for emergency repair of complicated abdominal wall hernias. World J Emerg Surg. 2017; 12:37. PMID: 28804507.
        View in: PubMed
      6. Sartelli M, Chichom-Mefire A, Labricciosa FM, Hardcastle T, Abu-Zidan FM, Adesunkanmi AK, Ansaloni L, Bala M, Balogh ZJ, Beltrán MA, Ben-Ishay O, Biffl WL, Birindelli A, Cainzos MA, Catalini G, Ceresoli M, Che Jusoh A, Chiara O, Coccolini F, Coimbra R, Cortese F, Demetrashvili Z, Di Saverio S, Diaz JJ, Egiev VN, Ferrada P, Fraga GP, Ghnnam WM, Lee JG, Gomes CA, Hecker A, Herzog T, Kim JI, Inaba K, Isik A, Karamarkovic A, Kashuk J, Khokha V, Kirkpatrick AW, Kluger Y, Koike K, Kong VY, Leppaniemi A, Machain GM, Maier RV, Marwah S, McFarlane ME, Montori G, Moore EE, Negoi I, Olaoye I, Omari AH, Ordonez CA, Pereira BM, Pereira Júnior GA, Pupelis G, Reis T, Sakakhushev B, Sato N, Segovia Lohse HA, Shelat VG, Søreide K, Uhl W, Ulrych J, Van Goor H, Velmahos GC, Yuan KC, Wani I, Weber DG, Zachariah SK, Catena F. The management of intra-abdominal infections from a global perspective: 2017 WSES guidelines for management of intra-abdominal infections. World J Emerg Surg. 2017; 12:29. PMID: 28702076.
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      7. Hassinger TE, Guidry CA, Rotstein OD, Duane TM, Evans HL, Cook CH, O'Neill PJ, Mazuski JE, Askari R, Napolitano LM, Namias N, Miller PR, Dellinger EP, Coimbra R, Cocanour CS, Banton KL, Cuschieri J, Popovsky K, Sawyer RG. Longer-Duration Antimicrobial Therapy Does Not Prevent Treatment Failure in High-Risk Patients with Complicated Intra-Abdominal Infections. Surg Infect (Larchmt). 2017 Aug/Sep; 18(6):659-663. PMID: 28650745.
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      8. Costantini TW, Coimbra R, Holcomb JB, Podbielski JM, Catalano RD, Blackburn A, Scalea TM, Stein DM, Williams L, Conflitti J, Keeney S, Hoey C, Zhou T, Sperry J, Skiada D, Inaba K, Williams BH, Minei JP, Privette A, Mackersie RC, Robinson BR, Moore FO. Pelvic fracture pattern predicts the need for hemorrhage control intervention-Results of an AAST multi-institutional study. J Trauma Acute Care Surg. 2017 Jun; 82(6):1030-1038. PMID: 28520685.
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      9. Zarzaur BL, Dunn JA, Leininger B, Lauerman M, Shanmuganathan K, Kaups K, Zamary K, Hartwell JL, Bhakta A, Myers J, Gordy S, Todd SR, Claridge JA, Teicher E, Sperry J, Privette A, Allawi A, Burlew CC, Maung AA, Davis KA, Cogbill T, Bonne S, Livingston DH, Coimbra R, Kozar RA. Natural history of splenic vascular abnormalities after blunt injury: A Western Trauma Association multicenter trial. J Trauma Acute Care Surg. 2017 May 30. PMID: 28570347.
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      10. Kobayashi L, Barmparas G, Bosarge P, Brown CV, Bukur M, Carrick MM, Catalano RD, Holly-Nicolas J, Inaba K, Kaminski S, Klein AL, Kopelman T, Ley EJ, Martinez EM, Moore FO, Murry J, Nirula R, Paul D, Quick J, Rivera O, Schreiber M, Coimbra R. Novel oral anticoagulants and trauma: The results of a prospective American Association for the Surgery of Trauma Multi-Institutional Trial. J Trauma Acute Care Surg. 2017 May; 82(5):827-835. PMID: 28431413.
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      11. Costantini TW, Coimbra R, Holcomb JB, Podbielski JM, Catalano R, Blackburn A, Scalea TM, Stein DM, Williams L, Conflitti J, Keeney S, Hoey C, Zhou T, Sperry J, Skiada D, Inaba K, Williams BH, Minei JP, Privette A, Mackersie RC, Robinson BR, Moore FO. Pelvic fracture pattern predicts the need for hemorrhage control intervention -- results of a AAST multi-institutional study. J Trauma Acute Care Surg. 2017 Mar 23. PMID: 28338600.
        View in: PubMed
      12. Lombardo S, Scalea T, Sperry J, Coimbra R, Vercruysse G, Enniss T, Jurkovich GJ, Nirula R. Neuro, trauma, or med/surg intensive care unit: Does it matter where multiple injuries patients with traumatic brain injury are admitted? Secondary analysis of the American Association for the Surgery of Trauma Multi-Institutional Trials Committee decompressive craniectomy study. J Trauma Acute Care Surg. 2017 Mar; 82(3):489-496. PMID: 28225527.
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      13. Moore L, Champion H, O'Reilly G, Leppaniemi A, Cameron P, Palmer C, Abu-Zidan FM, Gabbe B, Gaarder C, Yanchar N, Stelfox HT, Coimbra R, Kortbeek J, Noonan V, Gunning A, Leenan L, Gordon M, Khajanchi M, Shemilt M, Porgo V, Turgeon AF. Impact of trauma system structure on injury outcomes: a systematic review protocol. Syst Rev. 2017 Jan 21; 6(1):12. PMID: 28109306.
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      14. Coccolini F, Stahel PF, Montori G, Biffl W, Horer TM, Catena F, Kluger Y, Moore EE, Peitzman AB, Ivatury R, Coimbra R, Fraga GP, Pereira B, Rizoli S, Kirkpatrick A, Leppaniemi A, Manfredi R, Magnone S, Chiara O, Solaini L, Ceresoli M, Allievi N, Arvieux C, Velmahos G, Balogh Z, Naidoo N, Weber D, Abu-Zidan F, Sartelli M, Ansaloni L. Pelvic trauma: WSES classification and guidelines. World J Emerg Surg. 2017; 12:5. PMID: 28115984.
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      15. Langness S, Kojima M, Coimbra R, Eliceiri BP, Costantini TW. Enteric Glia Cells are Critical to Limiting the Intestinal Inflammatory Response After Injury. Am J Physiol Gastrointest Liver Physiol. 2017 Jan 12; ajpgi.00371.2016. PMID: 28082286.
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      16. Kojima M, Gimenes-Junior JA, Langness S, Morishita K, Lavoie-Gagne O, Eliceiri B, Costantini TW, Coimbra R. Exosomes, not protein or lipids, in mesenteric lymph activate inflammation: Unlocking the mystery of post-shock multiple organ failure. J Trauma Acute Care Surg. 2017 Jan; 82(1):42-50. PMID: 27779585.
        View in: PubMed
      17. Lombardo S, Scalea T, Sperry J, Coimbra R, Vercruysse G, Jurkovich GJ, Nirula R. Neuro-, Trauma -, or Med/Surg-ICU: Does it matter where polytrauma patients with TBI are admitted? Secondary analysis of AAST-MITC decompressive craniectomy study. J Trauma Acute Care Surg. 2016 Dec 23. PMID: 28030487.
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      18. Coimbra R, Kozar RA, Smith JW, Zarzaur BL, Hauser CJ, Moore FA, Bailey JA, Valadka A, Jurkovich GJ, Jenkins DH, Davis KA, Price MA, Maier RV. The Coalition for National Trauma Research (CNTR) Supports the Call for a National Trauma Research Action Plan. J Trauma Acute Care Surg. 2016 Dec 23. PMID: 28030499.
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      19. Berndtson AE, Costantini TW, Lane J, Box K, Coimbra R. If some is good, more is better: An enoxaparin dosing strategy to improve pharmacologic venous thromboembolism prophylaxis. J Trauma Acute Care Surg. 2016 Dec; 81(6):1095-1100. PMID: 27244575.
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      20. Jenkins DH, Winchell RJ, Coimbra R, Rotondo MF, Weireter LJ, Bulger EM, Kozar RA, Nathens AB, Reilly PM, Henry SM, Jimenez MF, Chang MC, Coburn M, Dodd J, Neal ML, Rosen J, Clemency J, Hoyt DB, Stewart RM. Position statement of the American College of Surgeons Committee on Trauma on the National Academies of Sciences, Engineering and Medicine Report, A National Trauma Care System: Integrating Military and Civilian Trauma Systems to Achieve Zero Preventable Deaths After Injury. J Trauma Acute Care Surg. 2016 Nov; 81(5):819-823. PMID: 27533902.
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      21. Coccolini F, Catena F, Moore EE, Ivatury R, Biffl W, Peitzman A, Coimbra R, Rizoli S, Kluger Y, Abu-Zidan FM, Ceresoli M, Montori G, Sartelli M, Weber D, Fraga G, Naidoo N, Moore FA, Zanini N, Ansaloni L. WSES classification and guidelines for liver trauma. World J Emerg Surg. 2016; 11:50. PMID: 27766112.
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      22. Baird A, Deng C, Eliceiri MH, Haghi F, Dang X, Coimbra R, Costantini TW, Torbett BE, Eliceiri BP. Mice engrafted with human hematopoietic stem cells support a human myeloid cell inflammatory response in vivo. Wound Repair Regen. 2016 Sep 24. PMID: 27663454.
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      23. Berndtson AE, Costantini TW, Smith AM, Kobayashi L, Coimbra R. Does sex matter? Effects on venous thromboembolism risk in screened trauma patients. J Trauma Acute Care Surg. 2016 Sep; 81(3):493-9. PMID: 27280942.
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      24. Rattan R, Allen CJ, Sawyer RG, Mazuski J, Duane TM, Askari R, Banton KL, Claridge JA, Coimbra R, Cuschieri J, Dellinger EP, Evans HL, Guidry CA, Miller PR, O'Neill PJ, Rotstein OD, West MA, Popovsky K, Namias N. Patients with Risk Factors for Complications Do Not Require Longer Antimicrobial Therapy for Complicated Intra-Abdominal Infection. Am Surg. 2016 Sep; 82(9):860-6. PMID: 27670577.
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      25. Rizoli S, Petersen A, Bulger E, Coimbra R, Kerby JD, Minei J, Morrison L, Nathens A, Schreiber M, de Oliveira Manoel AL. Early prediction of outcome after severe traumatic brain injury: a simple and practical model. BMC Emerg Med. 2016; 16(1):32. PMID: 27553436.
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      26. Sanders JM, Tessier JM, Sawyer RG, Lipsett PA, Miller PR, Namias N, O'Neill PJ, Dellinger EP, Coimbra R, Guidry CA, Cuschieri J, Banton KL, Cook CH, Moore BJ, Duane TM. Inclusion of Vancomycin as Part of Broad-Spectrum Coverage Does Not Improve Outcomes in Patients with Intra-Abdominal Infections: A Post Hoc Analysis. Surg Infect (Larchmt). 2016 Dec; 17(6):694-699. PMID: 27483362.
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      27. Sartelli M, Catena F, Ansaloni L, Coccolini F, Griffiths EA, Abu-Zidan FM, Di Saverio S, Ulrych J, Kluger Y, Ben-Ishay O, Moore FA, Ivatury RR, Coimbra R, Peitzman AB, Leppaniemi A, Fraga GP, Maier RV, Chiara O, Kashuk J, Sakakushev B, Weber DG, Latifi R, Biffl W, Bala M, Karamarkovic A, Inaba K, Ordonez CA, Hecker A, Augustin G, Demetrashvili Z, Melo RB, Marwah S, Zachariah SK, Shelat VG, McFarlane M, Rems M, Gomes CA, Faro MP, Júnior GA, Negoi I, Cui Y, Sato N, Vereczkei A, Bellanova G, Birindelli A, Di Carlo I, Kok KY, Gachabayov M, Gkiokas G, Bouliaris K, Çolak E, Isik A, Rios-Cruz D, Soto R, Moore EE. WSES Guidelines for the management of acute left sided colonic diverticulitis in the emergency setting. World J Emerg Surg. 2016; 11:37. PMID: 27478494.
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      28. Inaba K, Byerly S, Bush LD, Martin MJ, Martin D, Peck KA, Barmparas G, Bradley MJ, Hazelton JP, Coimbra R, Choudhry AJ, Brown CV, Ball CG, Cherry-Bukowiec JR, Burlew CC, Joseph B, Dunn J, Minshall CT, Carrick MM, Berg GM, Demetriades D. Cervical Spinal Clearance: A Prospective Western Trauma Association Multi-Institutional Trial. J Trauma Acute Care Surg. 2016 Jul 20. PMID: 27438681.
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      29. Di Saverio S, Birindelli A, Kelly MD, Catena F, Weber DG, Sartelli M, Sugrue M, De Moya M, Gomes CA, Bhangu A, Agresta F, Moore EE, Soreide K, Griffiths E, De Castro S, Kashuk J, Kluger Y, Leppaniemi A, Ansaloni L, Andersson M, Coccolini F, Coimbra R, Gurusamy KS, Campanile FC, Biffl W, Chiara O, Moore F, Peitzman AB, Fraga GP, Costa D, Maier RV, Rizoli S, Balogh ZJ, Bendinelli C, Cirocchi R, Tonini V, Piccinini A, Tugnoli G, Jovine E, Persiani R, Biondi A, Scalea T, Stahel P, Ivatury R, Velmahos G, Andersson R. WSES Jerusalem guidelines for diagnosis and treatment of acute appendicitis. World J Emerg Surg. 2016; 11:34. PMID: 27437029.
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      30. Sartelli M, Weber DG, Ruppé E, Bassetti M, Wright BJ, Ansaloni L, Catena F, Coccolini F, Abu-Zidan FM, Coimbra R, Moore EE, Moore FA, Maier RV, De Waele JJ, Kirkpatrick AW, Griffiths EA, Eckmann C, Brink AJ, Mazuski JE, May AK, Sawyer RG, Mertz D, Montravers P, Kumar A, Roberts JA, Vincent JL, Watkins RR, Lowman W, Spellberg B, Abbott IJ, Adesunkanmi AK, Al-Dahir S, Al-Hasan MN, Agresta F, Althani AA, Ansari S, Ansumana R, Augustin G, Bala M, Balogh ZJ, Baraket O, Bhangu A, Beltrán MA, Bernhard M, Biffl WL, Boermeester MA, Brecher SM, Cherry-Bukowiec JR, Buyne OR, Cainzos MA, Cairns KA, Camacho-Ortiz A, Chandy SJ, Che Jusoh A, Chichom-Mefire A, Colijn C, Corcione F, Cui Y, Curcio D, Delibegovic S, Demetrashvili Z, De Simone B, Dhingra S, Diaz JJ, Di Carlo I, Dillip A, Di Saverio S, Doyle MP, Dorj G, Dogjani A, Dupont H, Eachempati SR, Enani MA, Egiev VN, Elmangory MM, Ferrada P, Fitchett JR, Fraga GP, Guessennd N, Giamarellou H, Ghnnam W, Gkiokas G, Goldberg SR, Gomes CA, Gomi H, Guzmán-Blanco M, Haque M, Hansen S, Hecker A, Heizmann WR, Herzog T, Hodonou AM, Hong SK, Kafka-Ritsch R, Kaplan LJ, Kapoor G, Karamarkovic A, Kees MG, Kenig J, Kiguba R, Kim PK, Kluger Y, Khokha V, Koike K, Kok KY, Kong V, Knox MC, Inaba K, Isik A, Iskandar K, Ivatury RR, Labbate M, Labricciosa FM, Laterre PF, Latifi R, Lee JG, Lee YR, Leone M, Leppaniemi A, Li Y, Liang SY, Loho T, Maegele M, Malama S, Marei HE, Martin-Loeches I, Marwah S, Massele A, McFarlane M, Melo RB, Negoi I, Nicolau DP, Nord CE, Ofori-Asenso R, Omari AH, Ordonez CA, Ouadii M, Pereira Júnior GA, Piazza D, Pupelis G, Rawson TM, Rems M, Rizoli S, Rocha C, Sakakhushev B, Sanchez-Garcia M, Sato N, Segovia Lohse HA, Sganga G, Siribumrungwong B, Shelat VG, Soreide K, Soto R, Talving P, Tilsed JV, Timsit JF, Trueba G, Trung NT, Ulrych J, van Goor H, Vereczkei A, Vohra RS, Wani I, Uhl W, Xiao Y, Yuan KC, Zachariah SK, Zahar JR, Zakrison TL, Corcione A, Melotti RM, Viscoli C, Viale P. Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA). World J Emerg Surg. 2016; 11:33. PMID: 27429642.
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      31. Rattan R, Allen CJ, Sawyer RG, Askari R, Banton KL, Coimbra R, Cook CH, Duane TM, O'Neill PJ, Rotstein OD, Namias N. Percutaneously drained intra-abdominal infections do not require longer duration of antimicrobial therapy. J Trauma Acute Care Surg. 2016 Jul; 81(1):108-13. PMID: 26953758.
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      32. Langness S, Costantini TW, Smith A, Bansal V, Coimbra R. Isolated traumatic brain injury in patients with cirrhosis: do different treatment paradigms result in increased mortality? Am J Surg. 2017 Jan; 213(1):80-86. PMID: 27421188.
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      33. Costantini TW, Coimbra R, Holcomb JB, Podbielski JM, Catalano R, Blackburn A, Scalea TM, Stein DM, Williams L, Conflitti J, Keeney S, Suleiman G, Zhou T, Sperry J, Skiada D, Inaba K, Williams BH, Minei JP, Privette A, Mackersie RC, Robinson BR, Moore FO. Current management of hemorrhage from severe pelvic fractures: Results of an American Association for the Surgery of Trauma multi-institutional trial. J Trauma Acute Care Surg. 2016 May; 80(5):717-25. PMID: 26958799.
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      34. Baird A, Costantini T, Coimbra R, Eliceiri BP. Injury, inflammation and the emergence of human-specific genes. Wound Repair Regen. 2016 May; 24(3):602-6. PMID: 26874655.
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      35. Rattan R, Allen CJ, Sawyer RG, Askari R, Banton KL, Claridge JA, Cocanour CS, Coimbra R, Cook CH, Cuschieri J, Dellinger EP, Duane TM, Evans HL, Lipsett PA, Mazuski JE, Miller PR, O'Neill PJ, Rotstein OD, Namias N. Patients with Complicated Intra-Abdominal Infection Presenting with Sepsis Do Not Require Longer Duration of Antimicrobial Therapy. J Am Coll Surg. 2016 Apr; 222(4):440-6. PMID: 26920994.
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      36. Baird A, Coimbra R, Dang X, Eliceiri BP, Costantini TW. Up-regulation of the human-specific CHRFAM7A gene in inflammatory bowel disease. BBA Clin. 2016 Jun; 5:66-71. PMID: 27051591.
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      37. Costantini TW, Meads M, Dang X, Coimbra R, Torbett BE, Baird A, Eliceiri BP. The Response to Burn Injury in Mice With Human Hematolymphoid Systems. Ann Surg. 2016 Jan; 263(1):199-204. PMID: 25575256.
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      38. Sartelli M, Abu-Zidan FM, Catena F, Griffiths EA, Di Saverio S, Coimbra R, Ordoñez CA, Leppaniemi A, Fraga GP, Coccolini F, Agresta F, Abbas A, Abdel Kader S, Agboola J, Amhed A, Ajibade A, Akkucuk S, Alharthi B, Anyfantakis D, Augustin G, Baiocchi G, Bala M, Baraket O, Bayrak S, Bellanova G, Beltràn MA, Bini R, Boal M, Borodach AV, Bouliaris K, Branger F, Brunelli D, Catani M, Che Jusoh A, Chichom-Mefire A, Cocorullo G, Colak E, Costa D, Costa S, Cui Y, Curca GL, Curry T, Das K, Delibegovic S, Demetrashvili Z, Di Carlo I, Drozdova N, El Zalabany T, Enani MA, Faro M, Gachabayov M, Giménez Maurel T, Gkiokas G, Gomes CA, Gonsaga RA, Guercioni G, Guner A, Gupta S, Gutierrez S, Hutan M, Ioannidis O, Isik A, Izawa Y, Jain SA, Jokubauskas M, Karamarkovic A, Kauhanen S, Kaushik R, Kenig J, Khokha V, Kim JI, Kong V, Koshy R, Krasniqi A, Kshirsagar A, Kuliesius Z, Lasithiotakis K, Leão P, Lee JG, Leon M, Lizarazu Pérez A, Lohsiriwat V, López-Tomassetti Fernandez E, Lostoridis E, Mn R, Major P, Marinis A, Marrelli D, Martinez-Perez A, Marwah S, McFarlane M, Melo RB, Mesina C, Michalopoulos N, Moldovanu R, Mouaqit O, Munyika A, Negoi I, Nikolopoulos I, Nita GE, Olaoye I, Omari A, Ossa PR, Ozkan Z, Padmakumar R, Pata F, Pereira Junior GA, Pereira J, Pintar T, Pouggouras K, Prabhu V, Rausei S, Rems M, Rios-Cruz D, Sakakushev B, Sánchez de Molina ML, Seretis C, Shelat V, Simões RL, Sinibaldi G, Skrovina M, Smirnov D, Spyropoulos C, Tepp J, Tezcaner T, Tolonen M, Torba M, Ulrych J, Uzunoglu MY, van Dellen D, van Ramshorst GH, Vasquez G, Venara A, Vereczkei A, Vettoretto N, Vlad N, Yadav SK, Yilmaz TU, Yuan KC, Zachariah SK, Zida M, Zilinskas J, Ansaloni L. Global validation of the WSES Sepsis Severity Score for patients with complicated intra-abdominal infections: a prospective multicentre study (WISS Study). World J Emerg Surg. 2015; 10:61. PMID: 26677396.
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      39. Berndtson AE, Huang WT, Box K, Kobayashi L, Godat LN, Smith AM, Weingarten D, Coimbra R. A new kid on the block: Outcomes with Kcentra 1 year after approval. J Trauma Acute Care Surg. 2015 Dec; 79(6):1004-8. PMID: 26488322.
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      40. Meisinger QC, Brown MA, Dehqanzada ZA, Doucet J, Coimbra R, Casola G. A 10-year restrospective evaluation of ultrasound in pregnant abdominal trauma patients. Emerg Radiol. 2016 Apr; 23(2):105-9. PMID: 26585759.
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      41. Costantini TW, Coimbra R, Lopez NE, Lee JG, Potenza B, Smith A, Baird A, Eliceiri BP. Monitoring Neutrophil-Expressed Cell Surface Esophageal Cancer Related Gene-4 after Severe Burn Injury. Surg Infect (Larchmt). 2015 Dec; 16(6):669-74. PMID: 26460850.
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      42. Shah PM, Edwards BL, Dietch ZC, Guidry CA, Davies SW, Hennessy SA, Duane TM, O'Neill PJ, Coimbra R, Cook CH, Askari R, Popovsky K, Sawyer RG. Do Polymicrobial Intra-Abdominal Infections Have Worse Outcomes than Monomicrobial Intra-Abdominal Infections? Surg Infect (Larchmt). 2016 Jan; 17(1):27-31. PMID: 26397376.
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      47. Langness S, Coimbra R, Eliceiri BP, Costantini TW. Vagus Nerve Mediates the Neural Stem Cell Response to Intestinal Injury. J Am Coll Surg. 2015 Oct; 221(4):871-9. PMID: 26209457.
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      51. Sawyer RG, Claridge JA, Nathens AB, Rotstein OD, Duane TM, Evans HL, Cook CH, O'Neill PJ, Mazuski JE, Askari R, Wilson MA, Napolitano LM, Namias N, Miller PR, Dellinger EP, Watson CM, Coimbra R, Dent DL, Lowry SF, Cocanour CS, West MA, Banton KL, Cheadle WG, Lipsett PA, Guidry CA, Popovsky K. Trial of short-course antimicrobial therapy for intraabdominal infection. N Engl J Med. 2015 May 21; 372(21):1996-2005. PMID: 25992746.
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      52. Costantini TW, Dang X, Yurchyshyna MV, Coimbra R, Eliceiri BP, Baird A. A Human-Specific a7-Nicotinic Acetylcholine Receptor Gene in Human Leukocytes: Identification, Regulation and the Consequences of CHRFAM7A Expression. Mol Med. 2015; 21(1):323-36. PMID: 25860877.
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      53. Kim DY, Kobayashi L, Chang D, Fortlage D, Coimbra R. Early pharmacological venous thromboembolism prophylaxis is safe after operative fixation of traumatic spine fractures. Spine (Phila Pa 1976). 2015 Mar 1; 40(5):299-304. PMID: 25901977.
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      54. Guyette FX, Meier EN, Newgard C, McKnight B, Daya M, Bulger EM, Powell JL, Brasel KJ, Kerby JD, Egan D, Sise M, Coimbra R, Fabian TC, Hoyt DB. A comparison of prehospital lactate and systolic blood pressure for predicting the need for resuscitative care in trauma transported by ground. J Trauma Acute Care Surg. 2015 Mar; 78(3):600-6. PMID: 25710433.
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      93. Shackford SR, Kahl JE, Calvo RY, Shackford MC, Danos LA, Davis JW, Vercruysse GA, Feliciano DV, Moore EE, Moore HB, Knudson MM, Howard BM, Sise MJ, Coimbra R, Costantini TW, Brakenridge SC, Tominaga GT, Schaffer KB, Steele JT, Kennedy FR, Cogbill TH. Limb salvage after complex repairs of extremity arterial injuries is independent of surgical specialty training. J Trauma Acute Care Surg. 2013 Mar; 74(3):716-23; discussion 723-4. PMID: 23425727.
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      102. Kobayashi L, Costantini TW, Coimbra R. Hypovolemic shock resuscitation. Surg Clin North Am. 2012 Dec; 92(6):1403-23. PMID: 23153876.
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      103. Mohseni S, Talving P, Kobayashi L, Kim D, Inaba K, Lam L, Chan LS, Coimbra R, Demetriades D. Closed-suction drain placement at laparotomy in isolated solid organ injury is not associated with decreased risk of deep surgical site infection. Am Surg. 2012 Oct; 78(10):1187-91. PMID: 23025967.
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      104. Costantini TW, Eliceiri BP, Putnam JG, Bansal V, Baird A, Coimbra R. Intravenous phage display identifies peptide sequences that target the burn-injured intestine. Peptides. 2012 Nov; 38(1):94-9. PMID: 22960048.
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      106. Shaterian A, Kao S, Chen L, DiPietro LA, Coimbra R, Eliceiri BP, Baird A. The candidate tumor suppressor gene Ecrg4 as a wound terminating factor in cutaneous injury. Arch Dermatol Res. 2013 Mar; 305(2):141-9. PMID: 22899245.
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      114. Huang MX, Nichols S, Robb A, Angeles A, Drake A, Holland M, Asmussen S, D'Andrea J, Chun W, Levy M, Cui L, Song T, Baker DG, Hammer P, McLay R, Theilmann RJ, Coimbra R, Diwakar M, Boyd C, Neff J, Liu TT, Webb-Murphy J, Farinpour R, Cheung C, Harrington DL, Heister D, Lee RR. An automatic MEG low-frequency source imaging approach for detecting injuries in mild and moderate TBI patients with blast and non-blast causes. Neuroimage. 2012 Jul 16; 61(4):1067-82. PMID: 22542638.
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      115. Cauvi DM, Song D, Vazquez DE, Hawisher D, Bermudez JA, Williams MR, Bickler S, Coimbra R, De Maio A. Period of irreversible therapeutic intervention during sepsis correlates with phase of innate immune dysfunction. J Biol Chem. 2012 Jun 8; 287(24):19804-15. PMID: 22518839.
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      116. Dang X, Podvin S, Coimbra R, Eliceiri B, Baird A. Cell-specific processing and release of the hormone-like precursor and candidate tumor suppressor gene product, Ecrg4. Cell Tissue Res. 2012 Jun; 348(3):505-14. PMID: 22526622.
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      120. Krzyzaniak M, Ortiz-Pomales Y, Lopez N, Reys LG, Cheadle G, Wolf P, Eliceiri B, Bansal V, Baird A, Coimbra R. CPSI-121 pharmacologically prevents intestinal barrier dysfunction after cutaneous burn through a vagus nerve-dependent mechanism. J Trauma Acute Care Surg. 2012 Feb; 72(2):355-61; discussion 361-3. PMID: 22327977.
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      128. Podvin S, Gonzalez AM, Miller MC, Dang X, Botfield H, Donahue JE, Kurabi A, Boissaud-Cooke M, Rossi R, Leadbeater WE, Johanson CE, Coimbra R, Stopa EG, Eliceiri BP, Baird A. Esophageal cancer related gene-4 is a choroid plexus-derived injury response gene: evidence for a biphasic response in early and late brain injury. PLoS One. 2011; 6(9):e24609. PMID: 21935431.
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      132. Hill L, Rybar J, Baird S, Concha-Garcia S, Coimbra R, Patrick K. Road safe seniors: Screening for age-related driving disorders in inpatient and outpatient settings. J Safety Res. 2011 Jun; 42(3):165-9. PMID: 21855686.
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      138. Doucet JJ, Galarneau MR, Potenza BM, Bansal V, Lee JG, Schwartz AK, Dougherty AL, Dye J, Hollingsworth-Fridlund P, Fortlage D, Coimbra R. Combat versus civilian open tibia fractures: the effect of blast mechanism on limb salvage. J Trauma. 2011 May; 70(5):1241-7. PMID: 21610438.
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      139. Han PP, Holbrook TL, Sise MJ, Sack DI, Sise CB, Hoyt DB, Coimbra R, Potenza B, Anderson JP. Postinjury depression is a serious complication in adolescents after major trauma: injury severity and injury-event factors predict depression and long-term quality of life deficits. J Trauma. 2011 Apr; 70(4):923-30. PMID: 21610397.
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      143. Lopez N, Kobayashi L, Coimbra R. A Comprehensive review of abdominal infections. World J Emerg Surg. 2011; 6:7. PMID: 21345232.
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      145. Moore EE, Knudson MM, Burlew CC, Inaba K, Dicker RA, Biffl WL, Malhotra AK, Schreiber MA, Browder TD, Coimbra R, Gonzalez EA, Meredith JW, Livingston DH, Kaups KL. Defining the limits of resuscitative emergency department thoracotomy: a contemporary Western Trauma Association perspective. J Trauma. 2011 Feb; 70(2):334-9. PMID: 21307731.
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      146. Drummond R, Song D, Hawisher D, Wolf PL, Vazquez DE, Nino DF, Coimbra R, Cauvi DM, De Maio A. Acute acalculous cholecystitis-like phenotype in scavenger receptor A knock-out mice. J Surg Res. 2012 May 15; 174(2):344-51. PMID: 21474146.
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      165. Sallum EA, Sinozaki S, Calil AM, Coimbra R, Silva MR, Figueiredo LF, Birolini D. Blood loss and transcapillary refill in uncontrolled treated hemorrhage in dogs. Clinics (Sao Paulo). 2010; 65(1):67-78. PMID: 20126348.
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      172. Peterson CY, Shaterian A, Borboa AK, Gonzalez AM, Potenza BM, Coimbra R, Eliceiri BP, Baird A. The noninvasive, quantitative, in vivo assessment of adenoviral-mediated gene delivery in skin wound biomaterials. Biomaterials. 2009 Dec; 30(35):6788-93. PMID: 19781761.
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      173. Coimbra R, Conroy C, Tominaga GT, Bansal V, Schwartz A. Causes of scapula fractures differ from other shoulder injuries in occupants seriously injured during motor vehicle crashes. Injury. 2010 Feb; 41(2):151-5. PMID: 19660750.
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      174. Costantini TW, Fraga G, Fortlage D, Wynn S, Fraga A, Lee J, Doucet J, Bansal V, Coimbra R. Redefining renal dysfunction in trauma: implementation of the Acute Kidney Injury Network staging system. J Trauma. 2009 Aug; 67(2):283-7; discussion 287-8. PMID: 19667880.
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      189. de Campos T, Deree J, Martins JO, Loomis WH, Shenvi E, Putnam JG, Coimbra R. Pentoxifylline attenuates pulmonary inflammation and neutrophil activation in experimental acute pancreatitis. Pancreas. 2008 Jul; 37(1):42-9. PMID: 18580443.
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      190. Deree J, Martins JO, Melbostad H, Loomis WH, Coimbra R. Insights into the regulation of TNF-alpha production in human mononuclear cells: the effects of non-specific phosphodiesterase inhibition. Clinics (Sao Paulo). 2008 Jun; 63(3):321-8. PMID: 18568240.
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      192. Conroy C, Tominaga GT, Erwin S, Pacyna S, Velky T, Kennedy F, Sise M, Coimbra R. The influence of vehicle damage on injury severity of drivers in head-on motor vehicle crashes. Accid Anal Prev. 2008 Jul; 40(4):1589-94. PMID: 18606294.
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      193. Coimbra R, Conroy C, Hoyt DB, Pacyna S, May M, Erwin S, Tominaga G, Kennedy F, Sise M, Velky T. The influence of damage distribution on serious brain injury in occupants in frontal motor vehicle crashes. Accid Anal Prev. 2008 Jul; 40(4):1569-75. PMID: 18606291.
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      194. Deree J, Loomis WH, Wolf P, Coimbra R. Hepatic transcription factor activation and proinflammatory mediator production is attenuated by hypertonic saline and pentoxifylline resuscitation after hemorrhagic shock. J Trauma. 2008 May; 64(5):1230-8; discussion 1238-9. PMID: 18469645.
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      195. Herrera FA, Coimbra R, Easter DW. Penetrating colon injuries: primary anastomosis versus diversion. J Surg Educ. 2008 Jan-Feb; 65(1):31-5. PMID: 18308278.
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      196. Deree J, Martins J, de Campos T, Putnam JG, Loomis WH, Wolf P, Coimbra R. Pentoxifylline attenuates lung injury and modulates transcription factor activity in hemorrhagic shock. J Surg Res. 2007 Nov; 143(1):99-108. PMID: 17950078.
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      197. Brasel KJ, Bulger E, Cook AJ, Morrison LJ, Newgard CD, Tisherman SA, Kerby JD, Coimbra R, Hata JS, Hoyt DB. Hypertonic resuscitation: design and implementation of a prehospital intervention trial. J Am Coll Surg. 2008 Feb; 206(2):220-32. PMID: 18222373.
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      198. Bansal V, Fortlage D, Lee JG, Hill LL, Potenza B, Coimbra R. Significant injury in cruise ship passengers a case series. Am J Prev Med. 2007 Sep; 33(3):219-21. PMID: 17826583.
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      199. Deree J, Melbostad H, Loomis WH, Putnam JG, Coimbra R. The effects of a novel resuscitation strategy combining pentoxifylline and hypertonic saline on neutrophil MAPK signaling. Surgery. 2007 Aug; 142(2):276-83. PMID: 17689696.
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      200. Frankel DA, Acosta JA, Anjaria DJ, Porcides RD, Wolf PL, Coimbra R, Hoyt DB. Physiologic response to hemorrhagic shock depends on rate and means of hemorrhage. J Surg Res. 2007 Dec; 143(2):276-80. PMID: 17574590.
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      201. Coimbra R, Lee J, Bansal V, Hollingsworth-Fridlund P. Recognizing/accepting futility: prehospital, emergency center, operating room, and intensive care unit. J Trauma Nurs. 2007 Apr-Jun; 14(2):73-6; quiz 77-8. PMID: 17579324.
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      202. Deree J, de Campos T, Shenvi E, Loomis WH, Hoyt DB, Coimbra R. Hypertonic saline and pentoxifylline attenuates gut injury after hemorrhagic shock: the kinder, gentler resuscitation. J Trauma. 2007 Apr; 62(4):818-27; discussion 827-8. PMID: 17426535.
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      203. Holbrook TL, Hoyt DB, Coimbra R, Potenza B, Sise MJ, Sack DI, Anderson JP. Trauma in adolescents causes long-term marked deficits in quality of life: adolescent children do not recover preinjury quality of life or function up to two years postinjury compared to national norms. J Trauma. 2007 Mar; 62(3):577-83; discussion 583. PMID: 17414331.
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      204. De Campos T, Deree J, Coimbra R. From acute pancreatitis to end-organ injury: mechanisms of acute lung injury. Surg Infect (Larchmt). 2007 Feb; 8(1):107-20. PMID: 17381402.
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      205. Hoyt DB, Coimbra R. Trauma systems. Surg Clin North Am. 2007 Feb; 87(1):21-35, v-vi. PMID: 17127121.
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      206. Deree J, Shenvi E, Fortlage D, Stout P, Potenza B, Hoyt DB, Coimbra R. Patient factors and operating room resuscitation predict mortality in traumatic abdominal aortic injury: a 20-year analysis. J Vasc Surg. 2007 Mar; 45(3):493-7. PMID: 17254736.
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      207. Karmy-Jones R, Jurkovich GJ, Velmahos GC, Burdick T, Spaniolas K, Todd SR, McNally M, Jacoby RC, Link D, Janczyk RJ, Ivascu FA, McCann M, Obeid F, Hoff WS, McQuay N, Tieu BH, Schreiber MA, Nirula R, Brasel K, Dunn JA, Gambrell D, Huckfeldt R, Harper J, Schaffer KB, Tominaga GT, Vinces FY, Sperling D, Hoyt D, Coimbra R, Rosengart MR, Forsythe R, Cothren C, Moore EE, Haut ER, Hayanga AJ, Hird L, White C, Grossman J, Nagy K, Livaudais W, Wood R, Zengerink I, Kortbeek JB. Practice patterns and outcomes of retrievable vena cava filters in trauma patients: an AAST multicenter study. J Trauma. 2007 Jan; 62(1):17-24; discussion 24-5. PMID: 17215729.
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      208. Deree J, Martins JO, Leedom A, Lamon B, Putnam J, de Campos T, Hoyt DB, Wolf P, Coimbra R. Hypertonic saline and pentoxifylline reduces hemorrhagic shock resuscitation-induced pulmonary inflammation through attenuation of neutrophil degranulation and proinflammatory mediator synthesis. J Trauma. 2007 Jan; 62(1):104-11. PMID: 17215740.
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      209. Coimbra R, Hoyt DB, Engelhart S, Fortlage D. Nonoperative management reduces the overall mortality of grades 3 and 4 blunt liver injuries. Int Surg. 2006 Sep-Oct; 91(5):251-7. PMID: 17061668.
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      210. Deree J, Lall R, Melbostad H, Loomis W, Hoyt DB, Coimbra R. Pentoxifylline attenuates stored blood-induced inflammation: A new perspective on an old problem. Surgery. 2006 Aug; 140(2):186-91. PMID: 16904968.
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      211. Acosta JA, Hoyt DB, Schmid-Schönbein GW, Hugli TE, Anjaria DJ, Frankel DA, Coimbra R. Intraluminal pancreatic serine protease activity, mucosal permeability, and shock: a review. Shock. 2006 Jul; 26(1):3-9. PMID: 16783190.
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      212. Deree J, Lall R, Melbostad H, Grant M, Hoyt DB, Coimbra R. Neutrophil degranulation and the effects of phosphodiesterase inhibition. J Surg Res. 2006 Jun 1; 133(1):22-8. PMID: 16690368.
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      213. de Oliveira Martins J, Meyer-Pflug AR, Alba-Loureiro TC, Melbostad H, Costa da Cruz JW, Coimbra R, Curi R, Sannomiya P. Modulation of lipopolysaccharide-induced acute lung inflammation: Role of insulin. Shock. 2006 Mar; 25(3):260-6. PMID: 16552358.
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      214. Coimbra R, Porcides R, Loomis W, Melbostad H, Lall R, Deree J, Wolf P, Hoyt DB. HSPTX protects against hemorrhagic shock resuscitation-induced tissue injury: an attractive alternative to Ringer's lactate. J Trauma. 2006 Jan; 60(1):41-51. PMID: 16456435.
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      215. Coimbra R, Melbostad H, Loomis W, Porcides RD, Wolf P, Tobar M, Hoyt DB. LPS-induced acute lung injury is attenuated by phosphodiesterase inhibition: effects on proinflammatory mediators, metalloproteinases, NF-kappaB, and ICAM-1 expression. J Trauma. 2006 Jan; 60(1):115-25. PMID: 16456445.
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      216. Livingston DH, Lavery RF, Mosenthal AC, Knudson MM, Lee S, Morabito D, Manley GT, Nathens A, Jurkovich G, Hoyt DB, Coimbra R. Recovery at one year following isolated traumatic brain injury: a Western Trauma Association prospective multicenter trial. J Trauma. 2005 Dec; 59(6):1298-304; discussion 1304. PMID: 16394900.
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      217. Holbrook TL, Hoyt DB, Coimbra R, Potenza B, Sise M, Anderson JP. High rates of acute stress disorder impact quality-of-life outcomes in injured adolescents: mechanism and gender predict acute stress disorder risk. J Trauma. 2005 Nov; 59(5):1126-30. PMID: 16385290.
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      218. Lall RN, Loomis W, Melbostad H, Hoyt DB, Lane T, Coimbra R. Phosphodiesterase inhibition attenuates stored blood-induced neutrophil activation: a novel adjunct to blood transfusion. J Am Coll Surg. 2006 Jan; 202(1):10-7. PMID: 16377492.
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      219. Coimbra R, Melbostad H, Loomis W, Tobar M, Hoyt DB. Phosphodiesterase inhibition decreases nuclear factor-kappaB activation and shifts the cytokine response toward anti-inflammatory activity in acute endotoxemia. J Trauma. 2005 Sep; 59(3):575-82. PMID: 16361898.
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      220. Coimbra R, Loomis W, Melbostad H, Tobar M, Porcides RD, Lall R, Holbrook T, Hoyt DB. Role of hypertonic saline and pentoxifylline on neutrophil activation and tumor necrosis factor-alpha synthesis: a novel resuscitation strategy. J Trauma. 2005 Aug; 59(2):257-64; discussion 264-5. PMID: 16294063.
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      221. Coimbra R, Hoyt DB, Anjaria DJ, Potenza BM, Fortlage D, Hollingsworth-Fridlund P. Reversal of anticoagulation in trauma: a North-American survey on clinical practices among trauma surgeons. J Trauma. 2005 Aug; 59(2):375-82. PMID: 16294078.
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      222. Holbrook TL, Hoyt DB, Coimbra R, Potenza B, Sise M, Anderson JP. Long-term posttraumatic stress disorder persists after major trauma in adolescents: new data on risk factors and functional outcome. J Trauma. 2005 Apr; 58(4):764-9; discussion 769-71. PMID: 15824653.
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      223. Coimbra R, Porcides RD, Melbostad H, Loomis W, Tobar M, Hoyt DB, Wolf P. Nonspecific phosphodiesterase inhibition attenuates liver injury in acute endotoxemia. Surg Infect (Larchmt). 2005; 6(1):73-85. PMID: 15865553.
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      224. Coimbra R. From the trauma surgeon's viewpoint: multiple injuries--which cavity to open first? J Trauma Nurs. 2005 Jan-Mar; 12(1):7-9. PMID: 15916311.
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      225. Ku JK, Vasquez JC, Hoyt DB, Coimbra R. Metastatic meningioma to the liver successfully treated with a wedge resection and radiation therapy: report of a case. Surg Today. 2005; 35(1):82-5. PMID: 15622471.
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      226. Coimbra R, Loomis W, Melbostad H, Tobar M, Porcides RD, Hoyt DB. LPS-stimulated PMN activation and proinflammatory mediator synthesis is downregulated by phosphodiesterase inhibition: role of pentoxifylline. J Trauma. 2004 Dec; 57(6):1157-63. PMID: 15625444.
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      227. Yada-Langui MM, Anjos-Valotta EA, Sannomiya P, Rocha e Silva M, Coimbra R. Resuscitation affects microcirculatory polymorphonuclear leukocyte behavior after hemorrhagic shock: role of hypertonic saline and pentoxifylline. Exp Biol Med (Maywood). 2004 Jul; 229(7):684-93. PMID: 15229363.
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      228. Farrier J, Dinerman C, Hoyt DB, Coimbra R. Intestinal lymphoma causing intussusception in HIV(+) patient: a rare presentation. Curr Surg. 2004 Jul-Aug; 61(4):386-9. PMID: 15276346.
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      229. Kaw LL, Coimbra R, Potenza BM, Garfin SR, Hoyt DB. The use of recombinant factor VIIa for severe intractable bleeding during spine surgery. Spine (Phila Pa 1976). 2004 Jun 15; 29(12):1384-7; discussion 1388. PMID: 15187645.
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      230. Mosenthal AC, Livingston DH, Lavery RF, Knudson MM, Lee S, Morabito D, Manley GT, Nathens A, Jurkovich G, Hoyt DB, Coimbra R. The effect of age on functional outcome in mild traumatic brain injury: 6-month report of a prospective multicenter trial. J Trauma. 2004 May; 56(5):1042-8. PMID: 15179244.
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      231. Coimbra R, Filho AR, Nesser RA, Rasslan S. Outcome from traumatic injury of the portal and superior mesenteric veins. Vasc Endovascular Surg. 2004 May-Jun; 38(3):249-55. PMID: 15181507.
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      232. Shukla A, Hashiguchi N, Chen Y, Coimbra R, Hoyt DB, Junger WG. Osmotic regulation of cell function and possible clinical applications. Shock. 2004 May; 21(5):391-400. PMID: 15087814.
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      233. Coimbra R, Razuk-Filho A, Yada-Langui MM, Rocha-E-Silva M. Intraarterial pulmonary pentoxifylline improves cardiac performance and oxygen utilization after hemorrhagic shock: a novel resuscitation strategy. Anesth Analg. 2004 May; 98(5):1439-46, table of contents. PMID: 15105227.
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      234. Kaw LL, Potenza BM, Coimbra R, Hoyt DB. Traumatic diaphragmatic hernia. J Am Coll Surg. 2004 Apr; 198(4):668-9. PMID: 15072074.
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      235. Doucet JJ, Hoyt DB, Coimbra R, Schmid-Schönbein GW, Junger WG, Paul L W, Loomis WH, Hugli TE. Inhibition of enteral enzymes by enteroclysis with nafamostat mesilate reduces neutrophil activation and transfusion requirements after hemorrhagic shock. J Trauma. 2004 Mar; 56(3):501-10; discussion 510-1. PMID: 15128119.
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      236. Coimbra R, Melbostad H, Hoyt DB. Effects of phosphodiesterase inhibition on the inflammatory response after shock: role of pentoxifylline. J Trauma. 2004 Feb; 56(2):442-9. PMID: 14960994.
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      237. Ku J, DeLaRosa J, Kang J, Hoyt D, Coimbra R. Acute cholecystitis with a hemocholecyst as an unusual presentation of gallbladder cancer: report of a case. Surg Today. 2004; 34(11):973-6. PMID: 15526137.
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      238. Potenza BM, Hoyt DB, Coimbra R, Fortlage D, Holbrook T, Hollingsworth-Fridlund P. The epidemiology of serious and fatal injury in San Diego County over an 11-year period. J Trauma. 2004 Jan; 56(1):68-75. PMID: 14749568.
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      239. Michetti C, Coimbra R, Hoyt DB, Loomis W, Junger W, Wolf P. Pentoxifylline reduces acute lung injury in chronic endotoxemia. J Surg Res. 2003 Nov; 115(1):92-9. PMID: 14572778.
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      240. Kramp WJ, Waldo S, Schmid-Schönbein GW, Hoyt D, Coimbra R, Hugli TE. Characterization of two classes of pancreatic shock factors: functional differences exhibited by hydrophilic and hydrophobic shock factors. Shock. 2003 Oct; 20(4):356-62. PMID: 14501950.
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      241. Wilson M, Davis DP, Coimbra R. Diagnosis and monitoring of hemorrhagic shock during the initial resuscitation of multiple trauma patients: a review. J Emerg Med. 2003 May; 24(4):413-22. PMID: 12745044.
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      242. Coimbra R, Hoyt DB, Potenza BM, Fortlage D, Hollingsworth-Fridlund P. Does sexual dimorphism influence outcome of traumatic brain injury patients? The answer is no! J Trauma. 2003 Apr; 54(4):689-700. PMID: 12707530.
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      243. Hoyt DB, Coimbra R, Potenza B, Doucet J, Fortlage D, Holingsworth-Fridlund P, Holbrook T. A twelve-year analysis of disease and provider complications on an organized level I trauma service: as good as it gets? J Trauma. 2003 Jan; 54(1):26-36; discussion 36-7. PMID: 12544896.
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      244. Rappold JF, Coimbra R, Hoyt DB, Potenza BM, Fortlage D, Holbrook T, Minard G. Female gender does not protect blunt trauma patients from complications and mortality. J Trauma. 2002 Sep; 53(3):436-41; discussion 441. PMID: 12352477.
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      245. Coimbra R, Silverio CC. [New strategies for mechanic ventilation in acute pulmonary lesion and in acute respiratory distress syndrome]. Rev Assoc Med Bras. 2001 Oct-Dec; 47(4):358-64. PMID: 11813053.
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