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Transcriptional analysis links B cells and TERT expression to favorable prognosis in head and neck cancer. PNAS Nexus. 2023 Mar; 2(3):pgad046.
Xian S, Dosset M, Castro A, Carter H, Zanetti M. PMID: 36909826; PMCID: PMC10003760.
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PubMed Mentions:
1
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Disulfiram's journey from rubber vulcanization to T-cell activation. EMBO J. 2022 08 16; 41(16):e111862.
Dosset M, Zanetti M. PMID: 35848116; PMCID: PMC9379543.
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Humans
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The Unfolded Protein Response at the Tumor-Immune Interface. Front Immunol. 2022; 13:823157.
Zanetti M, Xian S, Dosset M, Carter H. PMID: 35237269; PMCID: PMC8882736.
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PubMed Mentions:
8 Fields:
Translation:
HumansCells
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The unfolded protein response links tumor aneuploidy to local immune dysregulation. EMBO Rep. 2021 12 06; 22(12):e52509.
Xian S, Dosset M, Almanza G, Searles S, Sahani P, Waller TC, Jepsen K, Carter H, Zanetti M. PMID: 34698427; PMCID: PMC8647024.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Chemoradiation triggers antitumor Th1 and tissue resident memory-polarized immune responses to improve immune checkpoint inhibitors therapy. J Immunother Cancer. 2021 07; 9(7).
Lauret Marie Joseph E, Kirilovsky A, Lecoester B, El Sissy C, Boullerot L, Rangan L, Marguier A, Tochet F, Dosset M, Boustani J, Ravel P, Boidot R, Spehner L, Haicheur-Adjouri N, Marliot F, Pallandre JR, Bonnefoy F, Scripcariu V, Van den Eynde M, Cornillot E, Mirjolet C, Pages F, Adotevi O. PMID: 34230108; PMCID: PMC8261891.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCells
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Modulation of Determinant Factors to Improve Therapeutic Combinations with Immune Checkpoint Inhibitors. Cells. 2020 07 19; 9(7).
Dosset M, Joseph EL, Rivera Vargas T, Apetoh L. PMID: 32707692; PMCID: PMC7408477.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
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Telomerase and CD4 T Cell Immunity in Cancer. Cancers (Basel). 2020 Jun 25; 12(6).
Dosset M, Castro A, Carter H, Zanetti M. PMID: 32630460; PMCID: PMC7352225.
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PubMed Mentions:
12
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Immunoregulation and Clinical Implications of ANGPT2/TIE2+ M-MDSC Signature in Non-Small Cell Lung Cancer. Cancer Immunol Res. 2020 02; 8(2):268-279.
Lauret Marie Joseph E, Laheurte C, Jary M, Boullerot L, Asgarov K, Gravelin E, Bouard A, Rangan L, Dosset M, Borg C, Adotévi O. PMID: 31871121.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Cleaved Caspase-3 Transcriptionally Regulates Angiogenesis-Promoting Chemotherapy Resistance. Cancer Res. 2019 Dec 01; 79(23):5958-5970.
Bernard A, Chevrier S, Beltjens F, Dosset M, Viltard E, Lagrange A, Derangère V, Oudot A, Ghiringhelli F, Collin B, Apetoh L, Feron O, Chen S, Arnould L, Végran F, Boidot R. PMID: 31611309.
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PubMed Mentions:
33 Fields:
Translation:
HumansAnimalsCells
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Distinct prognostic value of circulating anti-telomerase CD4+ Th1 immunity and exhausted PD-1+/TIM-3+ T cells in lung cancer. Br J Cancer. 2019 08; 121(5):405-416.
Laheurte C, Dosset M, Vernerey D, Boullerot L, Gaugler B, Gravelin E, Kaulek V, Jacquin M, Cuche L, Eberst G, Jacoulet P, Fabre E, Le Pimpec-Barthes F, Tartour E, De Carvalho Bittencourt M, Westeel V, Adotévi O. PMID: 31358938; PMCID: PMC6738094.
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PubMed Mentions:
35 Fields:
Translation:
HumansCells
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Personalized identification of tumor-associated immunogenic neoepitopes in hepatocellular carcinoma in complete remission after sorafenib treatment. Oncotarget. 2018 Oct 23; 9(83):35394-35407.
Vrecko S, Guenat D, Mercier-Letondal P, Faucheu H, Dosset M, Royer B, Galaine J, Boidot R, Kim S, Jary M, Adotévi O, Borg C, Godet Y. PMID: 30459932; PMCID: PMC6226040.
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PubMed Mentions:
6 Fields:
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Circulating NKp46+ Natural Killer cells have a potential regulatory property and predict distinct survival in Non-Small Cell Lung Cancer. Oncoimmunology. 2019; 8(2):e1527498.
Picard E, Godet Y, Laheurte C, Dosset M, Galaine J, Beziaud L, Loyon R, Boullerot L, Lauret Marie Joseph E, Spehner L, Jacquin M, Eberst G, Gaugler B, Le Pimpec-Barthes F, Fabre E, Westeel V, Caignard A, Borg C, Adotévi O. PMID: 30713781; PMCID: PMC6343773.
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PubMed Mentions:
18 Fields:
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Magalie Dosset and Thaiz Rivera Vargas. SM J Biol. 2018; 1(4):1018.
Cancer therapy evolution: when genetics and epigenetics intertwine to create novel opportunities.
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PD-1/PD-L1 pathway: an adaptive immune resistance mechanism to immunogenic chemotherapy in colorectal cancer. Oncoimmunology. 2018; 7(6):e1433981.
Dosset M, Vargas TR, Lagrange A, Boidot R, Végran F, Roussey A, Chalmin F, Dondaine L, Paul C, Lauret Marie-Joseph E, Martin F, Ryffel B, Borg C, Adotévi O, Ghiringhelli F, Apetoh L. PMID: 29872568; PMCID: PMC5980491.
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PubMed Mentions:
114 Fields:
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Selective degradation of PU.1 during autophagy represses the differentiation and antitumour activity of TH9 cells. Nat Commun. 2017 09 15; 8(1):559.
Rivera Vargas T, Cai Z, Shen Y, Dosset M, Benoit-Lizon I, Martin T, Roussey A, Flavell RA, Ghiringhelli F, Apetoh L. PMID: 28916785; PMCID: PMC5602674.
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PubMed Mentions:
44 Fields:
Translation:
AnimalsCells
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Identification of a novel PD-L1 positive solid tumor transplantable in HLA-A*0201/DRB1*0101 transgenic mice. Oncotarget. 2017 07 25; 8(30):48959-48971.
Rangan L, Galaine J, Boidot R, Hamieh M, Dosset M, Francoual J, Beziaud L, Pallandre JR, Lauret Marie Joseph E, Asgarova A, Borg C, Al Saati T, Godet Y, Latouche JB, Valmary-Degano S, Adotévi O. PMID: 28430664; PMCID: PMC5564740.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Immunoprevalence and magnitude of HLA-DP4 versus HLA-DR-restricted spontaneous CD4(+) Th1 responses against telomerase in cancer patients. Oncoimmunology. 2016 May; 5(5):e1137416.
Laheurte C, Galaine J, Beziaud L, Dosset M, Kerzerho J, Jacquemard C, Gaugler B, Ferrand C, Dormoy A, Aubin F, Jacoulet P, Westeel V, Borg C, Tartour E, Godet Y, Maillère B, Adotévi O. PMID: 27467955; PMCID: PMC4910811.
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PubMed Mentions:
13 Fields:
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Immunogenicity evaluation of a rationally designed polytope construct encoding HLA-A*0201 restricted epitopes derived from Leishmania major related proteins in HLA-A2/DR1 transgenic mice: steps toward polytope vaccine. PLoS One. 2014; 9(10):e108848.
Seyed N, Taheri T, Vauchy C, Dosset M, Godet Y, Eslamifar A, Sharifi I, Adotevi O, Borg C, Rohrlich PS, Rafati S. PMID: 25310094; PMCID: PMC4195657.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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The transcription factor IRF1 dictates the IL-21-dependent anticancer functions of TH9 cells. Nat Immunol. 2014 Aug; 15(8):758-66.
Végran F, Berger H, Boidot R, Mignot G, Bruchard M, Dosset M, Chalmin F, Rébé C, Dérangère V, Ryffel B, Kato M, Prévost-Blondel A, Ghiringhelli F, Apetoh L. PMID: 24973819.
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PubMed Mentions:
109 Fields:
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AnimalsCells
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Universal tumor-reactive helper peptides from telomerase as new tools for anticancer vaccination. Oncoimmunology. 2013 Mar 01; 2(3):e23430.
Dosset M, Vauchy C, Beziaud L, Adotevi O, Godet Y. PMID: 23802085; PMCID: PMC3661170.
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PubMed Mentions:
9 Fields:
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Targeting antitumor CD4 helper T cells with universal tumor-reactive helper peptides derived from telomerase for cancer vaccine. Hum Vaccin Immunother. 2013 May; 9(5):1073-7.
Adotévi O, Dosset M, Galaine J, Beziaud L, Godet Y, Borg C. PMID: 23357860; PMCID: PMC3899142.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Is preexisting antitumor CD4 T cell response indispensable for the chemotherapy induced immune regression of cancer? Oncoimmunology. 2012 Dec 01; 1(9):1617-1619.
Godet Y, Dosset M, Borg C, Adotevi O. PMID: 23264913; PMCID: PMC3525622.
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8 Fields:
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Universal cancer peptide-based therapeutic vaccine breaks tolerance against telomerase and eradicates established tumor. Clin Cancer Res. 2012 Nov 15; 18(22):6284-95.
Dosset M, Godet Y, Vauchy C, Beziaud L, Lone YC, Sedlik C, Liard C, Levionnois E, Clerc B, Sandoval F, Daguindau E, Wain-Hobson S, Tartour E, Langlade-Demoyen P, Borg C, Adotévi O. PMID: 23032748.
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PubMed Mentions:
27 Fields:
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HumansAnimalsCells
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Analysis of spontaneous tumor-specific CD4 T-cell immunity in lung cancer using promiscuous HLA-DR telomerase-derived epitopes: potential synergistic effect with chemotherapy response. Clin Cancer Res. 2012 May 15; 18(10):2943-53.
Godet Y, Fabre E, Dosset M, Lamuraglia M, Levionnois E, Ravel P, Benhamouda N, Cazes A, Le Pimpec-Barthes F, Gaugler B, Langlade-Demoyen P, Pivot X, Saas P, Maillère B, Tartour E, Borg C, Adotévi O. PMID: 22407833.
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PubMed Mentions:
52 Fields:
Translation:
HumansCells
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Immunogenicity of a recombinant lentiviral vector carrying human telomerase tumor antigen in HLA-B*0702 transgenic mice. Vaccine. 2010 Aug 31; 28(38):6374-81.
Rusakiewicz S, Dosset M, Mollier K, Souque P, Charneau P, Wain-Hobson S, Langlade-Demoyen P, Adotévi O. PMID: 20654669.
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PubMed Mentions:
4 Fields:
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HumansAnimalsCells
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The angiogenic growth factor and biomarker midkine is a tumor-shared antigen. J Immunol. 2010 Jul 01; 185(1):418-23.
Kerzerho J, Adotevi O, Castelli FA, Dosset M, Bernardeau K, Szely N, Lang F, Tartour E, Maillere B. PMID: 20511550.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
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Targeting human telomerase reverse transcriptase with recombinant lentivector is highly effective to stimulate antitumor CD8 T-cell immunity in vivo. Blood. 2010 Apr 15; 115(15):3025-32.
Adotévi O, Mollier K, Neuveut C, Dosset M, Ravel P, Fridman WH, Tartour E, Charneau P, Wain-Hobson S, Langlade-Demoyen P. PMID: 20130242.
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PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCellsPHPublic Health