Eric Courchesne

Title(s)Recall Hcomp, Neurosciences
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Discovering Neural Biomarkers of Language and Social Development in ASD Toddlers
    NIH R01DC016385Sep 1, 2017 - Aug 31, 2022
    Role: Principal Investigator
    Developmental Functional Genomics in ASD Toddlers
    NIH R01MH110558Sep 1, 2016 - Jun 30, 2021
    Role: Principal Investigator
    Biomarkers of Autism at 12 months: From Brain Overgrowth to Genes
    NIH P50MH081755Aug 6, 2007 - Jun 30, 2014
    Role: Principal Investigator
    SMALL INSTRUMENTATION GRANT
    NIH S15NS033747Sep 1, 1994 - Aug 31, 1996
    Role: Principal Investigator
    MRL Neuroanatomy in Autism: From Infancy to Childhoood
    NIH R01NS019855Sep 10, 1983 - Jul 31, 2007
    Role: Principal Investigator
    fMRI Studies of Neural Dysfunction in Autistic Toddlers
    NIH R01MH036840Jul 1, 1982 - Jul 31, 2013
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Beyond the Spectrum: Subtype-Specific Molecular Insights into Autism Spectrum Disorder Via Multimodal Data Integration. medRxiv. 2024 Sep 23. Zahiri J, Mirzaie M, Duan K, Xiao Y, Aamodt C, Yang X, Nazari S, Andreason C, Lopez L, Barnes CC, Arias S, Nalabolu S, Garmire L, Wang T, Hoekzema K, Eichler EE, Pierce K, Lewis NE, Courchesne E. PMID: 39399028; PMCID: PMC11469458.
      View in: PubMed   Mentions:
    2. Differences in regional brain structure in toddlers with autism are related to future language outcomes. Nat Commun. 2024 Jun 13; 15(1):5075. Duan K, Eyler L, Pierce K, Lombardo MV, Datko M, Hagler DJ, Taluja V, Zahiri J, Campbell K, Barnes CC, Arias S, Nalabolu S, Troxel J, Ji P, Courchesne E. PMID: 38871689; PMCID: PMC11176156.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    3. Embryonic origin of two ASD subtypes of social symptom severity: the larger the brain cortical organoid size, the more severe the social symptoms. Mol Autism. 2024 05 25; 15(1):22. Courchesne E, Taluja V, Nazari S, Aamodt CM, Pierce K, Duan K, Stophaeros S, Lopez L, Barnes CC, Troxel J, Campbell K, Wang T, Hoekzema K, Eichler EE, Nani JV, Pontes W, Sanchez SS, Lombardo MV, de Souza JS, Hayashi MAF, Muotri AR. PMID: 38790065; PMCID: PMC11127428.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    4. Level of Attention to Motherese Speech as an Early Marker of Autism Spectrum Disorder. JAMA Netw Open. 2023 02 01; 6(2):e2255125. Pierce K, Wen TH, Zahiri J, Andreason C, Courchesne E, Barnes CC, Lopez L, Arias SJ, Esquivel A, Cheng A. PMID: 36753277; PMCID: PMC9909502.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    5. Examination of the impact of the Get SET Early program on equitable access to care within the screen-evaluate-treat chain in toddlers with autism spectrum disorder. Autism. 2023 08; 27(6):1790-1802. Pham C, Bacon EC, Grzybowski A, Carter-Barnes C, Arias S, Xu R, Lopez L, Courchesne E, Pierce K. PMID: 36629055; PMCID: PMC10333446.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. A predictive ensemble classifier for the gene expression diagnosis of ASD at ages 1 to 4 years. Mol Psychiatry. 2023 02; 28(2):822-833. Bao B, Zahiri J, Gazestani VH, Lopez L, Xiao Y, Kim R, Wen TH, Chiang AWT, Nalabolu S, Pierce K, Robasky K, Wang T, Hoekzema K, Eichler EE, Lewis NE, Courchesne E. PMID: 36266569; PMCID: PMC9908553.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    7. Publisher Correction: A phenotypic spectrum of autism is attributable to the combined effects of rare variants, polygenic risk and sex. Nat Genet. 2022 Aug; 54(8):1259. Antaki D, Guevara J, Maihofer AX, Klein M, Gujral M, Grove J, Carey CE, Hong O, Arranz MJ, Hervas A, Corsello C, Vaux KK, Muotri AR, Iakoucheva LM, Courchesne E, Pierce K, Gleeson JG, Robinson EB, Nievergelt CM, Sebat J. PMID: 35768728.
      View in: PubMed   Mentions: 3     Fields:    
    8. A phenotypic spectrum of autism is attributable to the combined effects of rare variants, polygenic risk and sex. Nat Genet. 2022 09; 54(9):1284-1292. Antaki D, Guevara J, Maihofer AX, Klein M, Gujral M, Grove J, Carey CE, Hong O, Arranz MJ, Hervas A, Corsello C, Vaux KK, Muotri AR, Iakoucheva LM, Courchesne E, Pierce K, Gleeson JG, Robinson EB, Nievergelt CM, Sebat J. PMID: 35654974; PMCID: PMC9474668.
      View in: PubMed   Mentions: 72     Fields:    Translation:Humans
    9. Large scale validation of an early-age eye-tracking biomarker of an autism spectrum disorder subtype. Sci Rep. 2022 03 11; 12(1):4253. Wen TH, Cheng A, Andreason C, Zahiri J, Xiao Y, Xu R, Bao B, Courchesne E, Barnes CC, Arias SJ, Pierce K. PMID: 35277549; PMCID: PMC8917231.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    10. Neural responses to affective speech, including motherese, map onto clinical and social eye tracking profiles in toddlers with ASD. Nat Hum Behav. 2022 03; 6(3):443-454. Xiao Y, Wen TH, Kupis L, Eyler LT, Goel D, Vaux K, Lombardo MV, Lewis NE, Pierce K, Courchesne E. PMID: 34980898.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    11. Development of a culturally and linguistically sensitive virtual reality educational platform to improve vaccine acceptance within a refugee population: the SHIFA community engagement-public health innovation programme. BMJ Open. 2021 09 14; 11(9):e051184. Streuli S, Ibrahim N, Mohamed A, Sharma M, Esmailian M, Sezan I, Farrell C, Sawyer M, Meyer D, El-Maleh K, Thamman R, Marchetti A, Lincoln A, Courchesne E, Sahid A, Bhavnani SP. PMID: 34521673; PMCID: PMC8442061.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansPHPublic Health
    12. Get SET Early to Identify and Treatment Refer Autism Spectrum Disorder at 1 Year and Discover Factors That Influence Early Diagnosis. J Pediatr. 2021 Sep; 236:179-188. Pierce K, Gazestani V, Bacon E, Courchesne E, Cheng A, Barnes CC, Nalabolu S, Cha D, Arias S, Lopez L, Pham C, Gaines K, Gyurjyan G, Cook-Clark T, Karins K. PMID: 33915154.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansPHPublic Health
    13. Multiple freeze-thaw cycles lead to a loss of consistency in poly(A)-enriched RNA sequencing. BMC Genomics. 2021 Jan 21; 22(1):69. Kellman BP, Baghdassarian HM, Pramparo T, Shamie I, Gazestani V, Begzati A, Li S, Nalabolu S, Murray S, Lopez L, Pierce K, Courchesne E, Lewis NE. PMID: 33478392; PMCID: PMC7818915.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    14. Prenatal Origins of ASD: The When, What, and How of ASD Development. Trends Neurosci. 2020 05; 43(5):326-342. Courchesne E, Gazestani VH, Lewis NE. PMID: 32353336; PMCID: PMC7373219.
      View in: PubMed   Mentions: 68     Fields:    Translation:Humans
    15. Identifying prognostic markers in autism spectrum disorder using eye tracking. Autism. 2020 04; 24(3):658-669. Bacon EC, Moore A, Lee Q, Carter Barnes C, Courchesne E, Pierce K. PMID: 31647314; PMCID: PMC7166165.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    16. A perturbed gene network containing PI3K-AKT, RAS-ERK and WNT-β-catenin pathways in leukocytes is linked to ASD genetics and symptom severity. Nat Neurosci. 2019 10; 22(10):1624-1634. Gazestani VH, Pramparo T, Nalabolu S, Kellman BP, Murray S, Lopez L, Pierce K, Courchesne E, Lewis NE. PMID: 31551593; PMCID: PMC6764590.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    17. Evaluation of the Diagnostic Stability of the Early Autism Spectrum Disorder Phenotype in the General Population Starting at 12 Months. JAMA Pediatr. 2019 06 01; 173(6):578-587. Pierce K, Gazestani VH, Bacon E, Barnes CC, Cha D, Nalabolu S, Lopez L, Moore A, Pence-Stophaeros S, Courchesne E. PMID: 31034004; PMCID: PMC6547081.
      View in: PubMed   Mentions: 126     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    18. The ASD Living Biology: from cell proliferation to clinical phenotype. Mol Psychiatry. 2019 01; 24(1):88-107. Courchesne E, Pramparo T, Gazestani VH, Lombardo MV, Pierce K, Lewis NE. PMID: 29934544; PMCID: PMC6309606.
      View in: PubMed   Mentions: 103     Fields:    Translation:HumansAnimals
    19. Naturalistic language sampling to characterize the language abilities of 3-year-olds with autism spectrum disorder. Autism. 2019 04; 23(3):699-712. Bacon EC, Osuna S, Courchesne E, Pierce K. PMID: 29754501; PMCID: PMC6212344.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    20. Paternally inherited cis-regulatory structural variants are associated with autism. Science. 2018 04 20; 360(6386):327-331. Brandler WM, Antaki D, Gujral M, Kleiber ML, Whitney J, Maile MS, Hong O, Chapman TR, Tan S, Tandon P, Pang T, Tang SC, Vaux KK, Yang Y, Harrington E, Juul S, Turner DJ, Thiruvahindrapuram B, Kaur G, Wang Z, Kingsmore SF, Gleeson JG, Bisson D, Kakaradov B, Telenti A, Venter JC, Corominas R, Toma C, Cormand B, Rueda I, Guijarro S, Messer KS, Nievergelt CM, Arranz MJ, Courchesne E, Pierce K, Muotri AR, Iakoucheva LM, Hervas A, Scherer SW, Corsello C, Sebat J. PMID: 29674594; PMCID: PMC6449150.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansCells
    21. The geometric preference subtype in ASD: identifying a consistent, early-emerging phenomenon through eye tracking. Mol Autism. 2018; 9:19. Moore A, Wozniak M, Yousef A, Barnes CC, Cha D, Courchesne E, Pierce K. PMID: 29581878; PMCID: PMC5861622.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    22. Rethinking the idea of late autism spectrum disorder onset. Dev Psychopathol. 2018 05; 30(2):553-569. Bacon EC, Courchesne E, Barnes CC, Cha D, Pence S, Schreibman L, Stahmer AC, Pierce K. PMID: 28803559; PMCID: PMC10515446.
      View in: PubMed   Mentions: 22  Translation:Humans
    23. To Screen or Not to Screen Universally for Autism is not the Question: Why the Task Force Got It Wrong. J Pediatr. 2016 09; 176:182-94. Pierce K, Courchesne E, Bacon E. PMID: 27421956; PMCID: PMC5679123.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansPHPublic Health
    24. Frequency and Complexity of De Novo Structural Mutation in Autism. Am J Hum Genet. 2016 Apr 07; 98(4):667-79. Brandler WM, Antaki D, Gujral M, Noor A, Rosanio G, Chapman TR, Barrera DJ, Lin GN, Malhotra D, Watts AC, Wong LC, Estabillo JA, Gadomski TE, Hong O, Fajardo KV, Bhandari A, Owen R, Baughn M, Yuan J, Solomon T, Moyzis AG, Maile MS, Sanders SJ, Reiner GE, Vaux KK, Strom CM, Zhang K, Muotri AR, Akshoomoff N, Leal SM, Pierce K, Courchesne E, Iakoucheva LM, Corsello C, Sebat J. PMID: 27018473; PMCID: PMC4833290.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    25. Cell cycle networks link gene expression dysregulation, mutation, and brain maldevelopment in autistic toddlers. Mol Syst Biol. 2015 Dec 14; 11(12):841. Pramparo T, Lombardo MV, Campbell K, Barnes CC, Marinero S, Solso S, Young J, Mayo M, Dale A, Ahrens-Barbeau C, Murray SS, Lopez L, Lewis N, Pierce K, Courchesne E. PMID: 26668231; PMCID: PMC4704485.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    26. Diffusion Tensor Imaging Provides Evidence of Possible Axonal Overconnectivity in Frontal Lobes in Autism Spectrum Disorder Toddlers. Biol Psychiatry. 2016 Apr 15; 79(8):676-84. Solso S, Xu R, Proudfoot J, Hagler DJ, Campbell K, Venkatraman V, Carter Barnes C, Ahrens-Barbeau C, Pierce K, Dale A, Eyler L, Courchesne E. PMID: 26300272; PMCID: PMC4699869.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansCells
    27. Prediction of autism by translation and immune/inflammation coexpressed genes in toddlers from pediatric community practices. JAMA Psychiatry. 2015 Apr; 72(4):386-94. Pramparo T, Pierce K, Lombardo MV, Carter Barnes C, Marinero S, Ahrens-Barbeau C, Murray SS, Lopez L, Xu R, Courchesne E. PMID: 25739104.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansCells
    28. Patches of disorganization in the neocortex of children with autism. N Engl J Med. 2014 Mar 27; 370(13):1209-1219. Stoner R, Chow ML, Boyle MP, Sunkin SM, Mouton PR, Roy S, Wynshaw-Boris A, Colamarino SA, Lein ES, Courchesne E. PMID: 24670167; PMCID: PMC4499461.
      View in: PubMed   Mentions: 340     Fields:    Translation:HumansCells
    29. Measuring outcome in an early intervention program for toddlers with autism spectrum disorder: use of a curriculum-based assessment. Autism Res Treat. 2014; 2014:964704. Bacon EC, Dufek S, Schreibman L, Stahmer AC, Pierce K, Courchesne E. PMID: 24711926; PMCID: PMC3966353.
      View in: PubMed   Mentions: 15  
    30. Blood-based gene expression signatures of infants and toddlers with autism. J Am Acad Child Adolesc Psychiatry. 2012 Sep; 51(9):934-44.e2. Glatt SJ, Tsuang MT, Winn M, Chandler SD, Collins M, Lopez L, Weinfeld M, Carter C, Schork N, Pierce K, Courchesne E. PMID: 22917206; PMCID: PMC3756503.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    31. Abnormal microglial-neuronal spatial organization in the dorsolateral prefrontal cortex in autism. Brain Res. 2012 May 25; 1456:72-81. Morgan JT, Chana G, Abramson I, Semendeferi K, Courchesne E, Everall IP. PMID: 22516109.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansCells
    32. Age-dependent brain gene expression and copy number anomalies in autism suggest distinct pathological processes at young versus mature ages. PLoS Genet. 2012; 8(3):e1002592. Chow ML, Pramparo T, Winn ME, Barnes CC, Li HR, Weiss L, Fan JB, Murray S, April C, Belinson H, Fu XD, Wynshaw-Boris A, Schork NJ, Courchesne E. PMID: 22457638; PMCID: PMC3310790.
      View in: PubMed   Mentions: 108     Fields:    Translation:HumansCells
    33. Preprocessing and Quality Control Strategies for Illumina DASL Assay-Based Brain Gene Expression Studies with Semi-Degraded Samples. Front Genet. 2012; 3:11. Chow ML, Winn ME, Li HR, April C, Wynshaw-Boris A, Fan JB, Fu XD, Courchesne E, Schork NJ. PMID: 22375143; PMCID: PMC3286152.
      View in: PubMed   Mentions: 14  
    34. A failure of left temporal cortex to specialize for language is an early emerging and fundamental property of autism. Brain. 2012 Mar; 135(Pt 3):949-60. Eyler LT, Pierce K, Courchesne E. PMID: 22350062; PMCID: PMC3286331.
      View in: PubMed   Mentions: 140     Fields:    Translation:Humans
    35. Neuron number and size in prefrontal cortex of children with autism. JAMA. 2011 Nov 09; 306(18):2001-10. Courchesne E, Mouton PR, Calhoun ME, Semendeferi K, Ahrens-Barbeau C, Hallet MJ, Barnes CC, Pierce K. PMID: 22068992.
      View in: PubMed   Mentions: 350     Fields:    Translation:HumansCells
    36. Genome-wide expression assay comparison across frozen and fixed postmortem brain tissue samples. BMC Genomics. 2011 Sep 10; 12:449. Chow ML, Li HR, Winn ME, April C, Barnes CC, Wynshaw-Boris A, Fan JB, Fu XD, Courchesne E, Schork NJ. PMID: 21906392; PMCID: PMC3179967.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    37. Disrupted neural synchronization in toddlers with autism. Neuron. 2011 Jun 23; 70(6):1218-25. Dinstein I, Pierce K, Eyler L, Solso S, Malach R, Behrmann M, Courchesne E. PMID: 21689606; PMCID: PMC3119852.
      View in: PubMed   Mentions: 179     Fields:    Translation:HumansCells
    38. Brain growth across the life span in autism: age-specific changes in anatomical pathology. Brain Res. 2011 Mar 22; 1380:138-45. Courchesne E, Campbell K, Solso S. PMID: 20920490; PMCID: PMC4500507.
      View in: PubMed   Mentions: 295     Fields:    Translation:Humans
    39. Microglial activation and increased microglial density observed in the dorsolateral prefrontal cortex in autism. Biol Psychiatry. 2010 Aug 15; 68(4):368-76. Morgan JT, Chana G, Pardo CA, Achim C, Semendeferi K, Buckwalter J, Courchesne E, Everall IP. PMID: 20674603.
      View in: PubMed   Mentions: 324     Fields:    Translation:HumansCells
    40. Longitudinal magnetic resonance imaging study of cortical development through early childhood in autism. J Neurosci. 2010 Mar 24; 30(12):4419-27. Schumann CM, Bloss CS, Barnes CC, Wideman GM, Carper RA, Akshoomoff N, Pierce K, Hagler D, Schork N, Lord C, Courchesne E. PMID: 20335478; PMCID: PMC2859218.
      View in: PubMed   Mentions: 265     Fields:    Translation:Humans
    41. Amygdala enlargement in toddlers with autism related to severity of social and communication impairments. Biol Psychiatry. 2009 Nov 15; 66(10):942-9. Schumann CM, Barnes CC, Lord C, Courchesne E. PMID: 19726029; PMCID: PMC2795360.
      View in: PubMed   Mentions: 141     Fields:    Translation:Humans
    42. Deviant functional magnetic resonance imaging patterns of brain activity to speech in 2-3-year-old children with autism spectrum disorder. Biol Psychiatry. 2008 Oct 01; 64(7):589-98. Redcay E, Courchesne E. PMID: 18672231; PMCID: PMC2879340.
      View in: PubMed   Mentions: 108     Fields:    Translation:Humans
    43. Functional abnormalities of the default network during self- and other-reflection in autism. Soc Cogn Affect Neurosci. 2008 Jun; 3(2):177-90. Kennedy DP, Courchesne E. PMID: 19015108; PMCID: PMC2555458.
      View in: PubMed   Mentions: 113     Fields:    Translation:Humans
    44. Functional neuroimaging of speech perception during a pivotal period in language acquisition. Dev Sci. 2008 Mar; 11(2):237-52. Redcay E, Haist F, Courchesne E. PMID: 18333980.
      View in: PubMed   Mentions: 53     Fields:    Translation:Humans
    45. The intrinsic functional organization of the brain is altered in autism. Neuroimage. 2008 Feb 15; 39(4):1877-85. Kennedy DP, Courchesne E. PMID: 18083565.
      View in: PubMed   Mentions: 250     Fields:    Translation:Humans
    46. Mapping early brain development in autism. Neuron. 2007 Oct 25; 56(2):399-413. Courchesne E, Pierce K, Schumann CM, Redcay E, Buckwalter JA, Kennedy DP, Morgan J. PMID: 17964254.
      View in: PubMed   Mentions: 369     Fields:    Translation:HumansCells
    47. fMRI during natural sleep as a method to study brain function during early childhood. Neuroimage. 2007 Dec; 38(4):696-707. Redcay E, Kennedy DP, Courchesne E. PMID: 17904385.
      View in: PubMed   Mentions: 45     Fields:    Translation:Humans
    48. Abnormalities on the neurological examination and EEG in young children with pervasive developmental disorders. J Autism Dev Disord. 2007 May; 37(5):887-93. Akshoomoff N, Farid N, Courchesne E, Haas R. PMID: 17048091; PMCID: PMC2094050.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    49. MRI neuroanatomy in young girls with autism: a preliminary study. J Am Acad Child Adolesc Psychiatry. 2007 Apr; 46(4):515-523. Bloss CS, Courchesne E. PMID: 17420687.
      View in: PubMed   Mentions: 60     Fields:    Translation:Humans
    50. No reduction of spindle neuron number in frontoinsular cortex in autism. Brain Cogn. 2007 Jul; 64(2):124-9. Kennedy DP, Semendeferi K, Courchesne E. PMID: 17353073.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    51. Failing to deactivate: resting functional abnormalities in autism. Proc Natl Acad Sci U S A. 2006 May 23; 103(21):8275-80. Kennedy DP, Redcay E, Courchesne E. PMID: 16702548; PMCID: PMC1472462.
      View in: PubMed   Mentions: 257     Fields:    Translation:Humans
    52. When is the brain enlarged in autism? A meta-analysis of all brain size reports. Biol Psychiatry. 2005 Jul 01; 58(1):1-9. Redcay E, Courchesne E. PMID: 15935993.
      View in: PubMed   Mentions: 227     Fields:    Translation:Humans
    53. Brain overgrowth in autism during a critical time in development: implications for frontal pyramidal neuron and interneuron development and connectivity. Int J Dev Neurosci. 2005 Apr-May; 23(2-3):153-70. Courchesne E, Pierce K. PMID: 15749242.
      View in: PubMed   Mentions: 147     Fields:    Translation:HumansCells
    54. Why the frontal cortex in autism might be talking only to itself: local over-connectivity but long-distance disconnection. Curr Opin Neurobiol. 2005 Apr; 15(2):225-30. Courchesne E, Pierce K. PMID: 15831407.
      View in: PubMed   Mentions: 407     Fields:    Translation:Humans
    55. Localized enlargement of the frontal cortex in early autism. Biol Psychiatry. 2005 Jan 15; 57(2):126-33. Carper RA, Courchesne E. PMID: 15652870.
      View in: PubMed   Mentions: 170     Fields:    Translation:HumansCTClinical Trials
    56. Auditory spatial localization and attention deficits in autistic adults. Brain Res Cogn Brain Res. 2005 May; 23(2-3):221-34. Teder-Sälejärvi WA, Pierce KL, Courchesne E, Hillyard SA. PMID: 15820630.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    57. Autism at the beginning: microstructural and growth abnormalities underlying the cognitive and behavioral phenotype of autism. Dev Psychopathol. 2005; 17(3):577-97. Courchesne E, Redcay E, Morgan JT, Kennedy DP. PMID: 16262983.
      View in: PubMed   Mentions: 77  Translation:HumansCells
    58. The functional neuroanatomy of spatial attention in autism spectrum disorder. Dev Neuropsychol. 2005; 27(3):425-58. Haist F, Adamo M, Westerfield M, Courchesne E, Townsend J. PMID: 15843105.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    59. The brain response to personally familiar faces in autism: findings of fusiform activity and beyond. Brain. 2004 Dec; 127(Pt 12):2703-16. Pierce K, Haist F, Sedaghat F, Courchesne E. PMID: 15319275.
      View in: PubMed   Mentions: 165     Fields:    Translation:Humans
    60. The autistic brain: birth through adulthood. Curr Opin Neurol. 2004 Aug; 17(4):489-96. Courchesne E, Redcay E, Kennedy DP. PMID: 15247547.
      View in: PubMed   Mentions: 56     Fields:    Translation:Humans
    61. Electroencephalographic brain dynamics following manually responded visual targets. PLoS Biol. 2004 Jun; 2(6):e176. Makeig S, Delorme A, Westerfield M, Jung TP, Townsend J, Courchesne E, Sejnowski TJ. PMID: 15208723; PMCID: PMC423146.
      View in: PubMed   Mentions: 132     Fields:    Translation:Humans
    62. Outcome classification of preschool children with autism spectrum disorders using MRI brain measures. J Am Acad Child Adolesc Psychiatry. 2004 Mar; 43(3):349-57. Akshoomoff N, Lord C, Lincoln AJ, Courchesne RY, Carper RA, Townsend J, Courchesne E. PMID: 15076269.
      View in: PubMed   Mentions: 54     Fields:    Translation:Humans
    63. Brain development in autism: early overgrowth followed by premature arrest of growth. Ment Retard Dev Disabil Res Rev. 2004; 10(2):106-11. Courchesne E. PMID: 15362165.
      View in: PubMed   Mentions: 118     Fields:    Translation:Humans
    64. Abnormal variability and distribution of functional maps in autism: an FMRI study of visuomotor learning. Am J Psychiatry. 2003 Oct; 160(10):1847-62. Müller RA, Kleinhans N, Kemmotsu N, Pierce K, Courchesne E. PMID: 14514501.
      View in: PubMed   Mentions: 72     Fields:    Translation:Humans
    65. Evidence of brain overgrowth in the first year of life in autism. JAMA. 2003 Jul 16; 290(3):337-44. Courchesne E, Carper R, Akshoomoff N. PMID: 12865374.
      View in: PubMed   Mentions: 356     Fields:    Translation:Humans
    66. Differential effects of developmental cerebellar abnormality on cognitive and motor functions in the cerebellum: an fMRI study of autism. Am J Psychiatry. 2003 Feb; 160(2):262-73. Allen G, Courchesne E. PMID: 12562572.
      View in: PubMed   Mentions: 109     Fields:    Translation:Humans
    67. Cerebellar abnormalities in infants and toddlers with Williams syndrome. Dev Med Child Neurol. 2002 Oct; 44(10):688-94. Jones W, Hesselink J, Courchesne E, Duncan T, Matsuda K, Bellugi U. PMID: 12418794.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    68. Relationship between head circumference and brain volume in healthy normal toddlers, children, and adults. Neuropediatrics. 2002 Oct; 33(5):239-41. Bartholomeusz HH, Courchesne E, Karns CM. PMID: 12536365.
      View in: PubMed   Mentions: 106     Fields:    Translation:Humans
    69. Cerebral lobes in autism: early hyperplasia and abnormal age effects. Neuroimage. 2002 Aug; 16(4):1038-51. Carper RA, Moses P, Tigue ZD, Courchesne E. PMID: 12202091.
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    70. Dynamic brain sources of visual evoked responses. Science. 2002 Jan 25; 295(5555):690-4. Makeig S, Westerfield M, Jung TP, Enghoff S, Townsend J, Courchesne E, Sejnowski TJ. PMID: 11809976.
      View in: PubMed   Mentions: 445     Fields:    Translation:Humans
    71. Abnormal early brain development in autism. Mol Psychiatry. 2002; 7 Suppl 2:S21-3. Courchesne E. PMID: 12142938.
      View in: PubMed   Mentions: 53     Fields:    Translation:Humans
    72. The neurobiological basis of autism from a developmental perspective. Dev Psychopathol. 2002; 14(3):613-34. Akshoomoff N, Pierce K, Courchesne E. PMID: 12349876.
      View in: PubMed   Mentions: 23  Translation:Humans
    73. Analysis and visualization of single-trial event-related potentials. Hum Brain Mapp. 2001 Nov; 14(3):166-85. Jung TP, Makeig S, Westerfield M, Townsend J, Courchesne E, Sejnowski TJ. PMID: 11559961; PMCID: PMC6871967.
      View in: PubMed   Mentions: 162     Fields:    Translation:Humans
    74. Face processing occurs outside the fusiform 'face area' in autism: evidence from functional MRI. Brain. 2001 Oct; 124(Pt 10):2059-73. Pierce K, Müller RA, Ambrose J, Allen G, Courchesne E. PMID: 11571222.
      View in: PubMed   Mentions: 272     Fields:    Translation:Humans
    75. Unusual brain growth patterns in early life in patients with autistic disorder: an MRI study. Neurology. 2001 Jul 24; 57(2):245-54. Courchesne E, Karns CM, Davis HR, Ziccardi R, Carper RA, Tigue ZD, Chisum HJ, Moses P, Pierce K, Lord C, Lincoln AJ, Pizzo S, Schreibman L, Haas RH, Akshoomoff NA, Courchesne RY. PMID: 11468308.
      View in: PubMed   Mentions: 521     Fields:    Translation:Humans
    76. Prenatal, perinatal, and neonatal factors in autism, pervasive developmental disorder-not otherwise specified, and the general population. Pediatrics. 2001 Apr; 107(4):E63. Juul-Dam N, Townsend J, Courchesne E. PMID: 11335784.
      View in: PubMed   Mentions: 60     Fields:    Translation:Humans
    77. Event-related brain response abnormalities in autism: evidence for impaired cerebello-frontal spatial attention networks. Brain Res Cogn Brain Res. 2001 Mar; 11(1):127-45. Townsend J, Westerfield M, Leaver E, Makeig S, Jung T, Pierce K, Courchesne E. PMID: 11240116.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCTClinical Trials
    78. Attention function and dysfunction in autism. Front Biosci. 2001 Feb 01; 6:D105-19. Allen G, Courchesne E. PMID: 11171544.
      View in: PubMed   Mentions: 85     Fields:    Translation:Humans
    79. Broca's area and the discrimination of frequency transitions: a functional MRI study. Brain Lang. 2001 Jan; 76(1):70-6. Müller RA, Kleinhans N, Courchesne E. PMID: 11161356.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    80. Regional size reduction in the human corpus callosum following pre- and perinatal brain injury. Cereb Cortex. 2000 Dec; 10(12):1200-10. Moses P, Courchesne E, Stiles J, Trauner D, Egaas B, Edwards E. PMID: 11073869.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    81. Removal of eye activity artifacts from visual event-related potentials in normal and clinical subjects. Clin Neurophysiol. 2000 Oct; 111(10):1745-58. Jung TP, Makeig S, Westerfield M, Townsend J, Courchesne E, Sejnowski TJ. PMID: 11018488.
      View in: PubMed   Mentions: 397     Fields:    Translation:Humans
    82. Normal brain development and aging: quantitative analysis at in vivo MR imaging in healthy volunteers. Radiology. 2000 Sep; 216(3):672-82. Courchesne E, Chisum HJ, Townsend J, Cowles A, Covington J, Egaas B, Harwood M, Hinds S, Press GA. PMID: 10966694.
      View in: PubMed   Mentions: 388     Fields:    Translation:Humans
    83. Inverse correlation between frontal lobe and cerebellum sizes in children with autism. Brain. 2000 Apr; 123 ( Pt 4):836-44. Carper RA, Courchesne E. PMID: 10734014.
      View in: PubMed   Mentions: 84     Fields:    Translation:Humans
    84. Exploring the neurofunctional organization of face processing in autism. Arch Gen Psychiatry. 2000 Apr; 57(4):344-6. Pierce K, Courchesne E. PMID: 10768695.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    85. Spatial attention deficits in patients with acquired or developmental cerebellar abnormality. J Neurosci. 1999 Jul 01; 19(13):5632-43. Townsend J, Courchesne E, Covington J, Westerfield M, Harris NS, Lyden P, Lowry TP, Press GA. PMID: 10377369; PMCID: PMC6782343.
      View in: PubMed   Mentions: 73     Fields:    Translation:Humans
    86. Neuroanatomic contributions to slowed orienting of attention in children with autism. Brain Res Cogn Brain Res. 1999 May; 8(1):61-71. Harris NS, Courchesne E, Townsend J, Carper RA, Lord C. PMID: 10216274.
      View in: PubMed   Mentions: 45     Fields:    Translation:Humans
    87. Brain weight in autism: normal in the majority of cases, megalencephalic in rare cases. Neurology. 1999 Mar 23; 52(5):1057-9. Courchesne E, Müller RA, Saitoh O. PMID: 10102428.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    88. Prediction and preparation, fundamental functions of the cerebellum. Learn Mem. 1997 May-Jun; 4(1):1-35. Courchesne E, Allen G. PMID: 10456051.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimals
    89. Brainstem, cerebellar and limbic neuroanatomical abnormalities in autism. Curr Opin Neurobiol. 1997 Apr; 7(2):269-78. Courchesne E. PMID: 9142760.
      View in: PubMed   Mentions: 101     Fields:    Translation:Humans
    90. Attentional activation of the cerebellum independent of motor involvement. Science. 1997 Mar 28; 275(5308):1940-3. Allen G, Buxton RB, Wong EC, Courchesne E. PMID: 9072973.
      View in: PubMed   Mentions: 200     Fields:    Translation:Humans
    91. Visual attention abnormalities in autism: delayed orienting to location. J Int Neuropsychol Soc. 1996 Nov; 2(6):541-50. Townsend J, Harris NS, Courchesne E. PMID: 9375158.
      View in: PubMed   Mentions: 48     Fields:    Translation:Humans
    92. Neurologic abnormalities in infantile autism. J Child Neurol. 1996 Mar; 11(2):84-92. Haas RH, Townsend J, Courchesne E, Lincoln AJ, Schreibman L, Yeung-Courchesne R. PMID: 8881982.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    93. Sensory modulation of auditory stimuli in children with autism and receptive developmental language disorder: event-related brain potential evidence. J Autism Dev Disord. 1995 Oct; 25(5):521-39. Lincoln AJ, Courchesne E, Harms L, Allen M. PMID: 8567597.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    94. Reduced size of corpus callosum in autism. Arch Neurol. 1995 Aug; 52(8):794-801. Egaas B, Courchesne E, Saitoh O. PMID: 7639631.
      View in: PubMed   Mentions: 107     Fields:    Translation:Humans
    95. NMR intensity of corpus callosum differs with age but not with diagnosis of autism. Neuroreport. 1995 Jun 19; 6(9):1253-6. Belmonte M, Egaas B, Townsend J, Courchesne E. PMID: 7669980.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    96. New evidence of cerebellar and brainstem hypoplasia in autistic infants, children and adolescents: the MR imaging study by Hashimoto and colleagues. J Autism Dev Disord. 1995 Feb; 25(1):19-22. Courchesne E. PMID: 7608031.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    97. Cross-sectional area of the posterior hippocampus in autistic patients with cerebellar and corpus callosum abnormalities. Neurology. 1995 Feb; 45(2):317-24. Saitoh O, Courchesne E, Egaas B, Lincoln AJ, Schreibman L. PMID: 7854533.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    98. A model system for the study of attention and the cerebellum: infantile autism. Electroencephalogr Clin Neurophysiol Suppl. 1995; 44:315-25. Courchesne E, Akshoomoff NA, Townsend J, Saitoh O. PMID: 7649039.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    99. Impairment in shifting attention in autistic and cerebellar patients. Behav Neurosci. 1994 Oct; 108(5):848-65. Courchesne E, Townsend J, Akshoomoff NA, Saitoh O, Yeung-Courchesne R, Lincoln AJ, James HE, Haas RH, Schreibman L, Lau L. PMID: 7826509.
      View in: PubMed   Mentions: 156     Fields:    Translation:Humans
    100. The brain in infantile autism: posterior fossa structures are abnormal. Neurology. 1994 Feb; 44(2):214-23. Courchesne E, Townsend J, Saitoh O. PMID: 8309561.
      View in: PubMed   Mentions: 50     Fields:    Translation:Humans
    101. Abnormality of cerebellar vermian lobules VI and VII in patients with infantile autism: identification of hypoplastic and hyperplastic subgroups with MR imaging. AJR Am J Roentgenol. 1994 Jan; 162(1):123-30. Courchesne E, Saitoh O, Yeung-Courchesne R, Press GA, Lincoln AJ, Haas RH, Schreibman L. PMID: 8273650.
      View in: PubMed   Mentions: 64     Fields:    Translation:Humans
    102. Contextual probability evaluation in autistic, receptive developmental language disorder, and control children: event-related brain potential evidence. J Autism Dev Disord. 1993 Mar; 23(1):37-58. Lincoln AJ, Courchesne E, Harms L, Allen M. PMID: 8463201.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    103. Parietal lobe abnormalities detected with MR in patients with infantile autism. AJR Am J Roentgenol. 1993 Feb; 160(2):387-93. Courchesne E, Press GA, Yeung-Courchesne R. PMID: 8424359.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    104. Auditory processing abilities in non-retarded adolescents and young adults with developmental receptive language disorder and autism. Brain Lang. 1992 Nov; 43(4):613-22. Lincoln AJ, Dickstein P, Courchesne E, Elmasian R, Tallal P. PMID: 1483193.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    105. A new role for the cerebellum in cognitive operations. Behav Neurosci. 1992 Oct; 106(5):731-8. Akshoomoff NA, Courchesne E. PMID: 1445653.
      View in: PubMed   Mentions: 57     Fields:    Translation:Humans
    106. In vivo myeloarchitectonic analysis of human striate and extrastriate cortex using magnetic resonance imaging. Cereb Cortex. 1992 Sep-Oct; 2(5):417-24. Clark VP, Courchesne E, Grafe M. PMID: 1422094.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansCells
    107. Cerebellar and cerebral abnormalities in Rett syndrome: a quantitative MR analysis. AJR Am J Roentgenol. 1992 Jul; 159(1):177-83. Murakami JW, Courchesne E, Haas RH, Press GA, Yeung-Courchesne R. PMID: 1609693.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    108. Contribution of the cerebellum to neuropsychological functioning: evidence from a case of cerebellar degenerative disorder. Neuropsychologia. 1992 Apr; 30(4):315-28. Akshoomoff NA, Courchesne E, Press GA, Iragui V. PMID: 1603296.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    109. Autism. New Dir Ment Health Serv. 1992; (54):19-23. Courchesne E. PMID: 1625655.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    110. Absence of magnetic resonance imaging evidence of pontine abnormality in infantile autism. Arch Neurol. 1991 Nov; 48(11):1160-3. Hsu M, Yeung-Courchesne R, Courchesne E, Press GA. PMID: 1953402.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    111. Neuroanatomic imaging in autism. Pediatrics. 1991 May; 87(5 Pt 2):781-90. Courchesne E. PMID: 2020537.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    112. The cerebellum: 3. Anatomic-MR correlation in the coronal plane. AJR Am J Roentgenol. 1990 Mar; 154(3):593-602. Press GA, Murakami JW, Courchesne E, Grafe M, Hesselink JR. PMID: 2106226.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    113. Effects of focused selective attention tasks on event-related potentials in autistic and normal individuals. Electroencephalogr Clin Neurophysiol. 1990 Mar; 75(3):207-20. Ciesielski KT, Courchesne E, Elmasian R. PMID: 1689644.
      View in: PubMed   Mentions: 52     Fields:    Translation:Humans
    114. The cerebellum: 3. Anatomic-MR correlation in the coronal plane. AJNR Am J Neuroradiol. 1990 Jan-Feb; 11(1):41-50. Press GA, Murakami JW, Courchesne E, Grafe M, Hesselink JR. PMID: 2105616; PMCID: PMC8332497.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    115. The cerebellum in sagittal plane--anatomic-MR correlation: 1. The vermis. AJR Am J Roentgenol. 1989 Oct; 153(4):829-35. Courchesne E, Press GA, Murakami J, Berthoty D, Grafe M, Wiley CA, Hesselink JR. PMID: 2773740.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    116. The cerebellum in sagittal plane--anatomic-MR correlation: 2. The cerebellar hemispheres. AJR Am J Roentgenol. 1989 Oct; 153(4):837-46. Press GA, Murakami J, Courchesne E, Berthoty DP, Grafe M, Wiley CA, Hesselink JR. PMID: 2773741.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    117. Brainstem auditory evoked potentials in receptive developmental language disorder. Brain Lang. 1989 Oct; 37(3):409-18. Akshoomoff N, Courchesne E, Yeung-Courchesne R, Costello J. PMID: 2804621.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    118. Reduced cerebellar hemisphere size and its relationship to vermal hypoplasia in autism. Arch Neurol. 1989 Jun; 46(6):689-94. Murakami JW, Courchesne E, Press GA, Yeung-Courchesne R, Hesselink JR. PMID: 2730382.
      View in: PubMed   Mentions: 46     Fields:    Translation:Humans
    119. Brainstem and middle latency auditory evoked potentials in autism and developmental language disorder. J Autism Dev Disord. 1989 Jun; 19(2):255-69. Grillon C, Courchesne E, Akshoomoff N. PMID: 2745391.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    120. Pathophysiologic findings in nonretarded autism and receptive developmental language disorder. J Autism Dev Disord. 1989 Mar; 19(1):1-17. Courchesne E, Lincoln AJ, Yeung-Courchesne R, Elmasian R, Grillon C. PMID: 2708293.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    121. A study of intellectual abilities in high-functioning people with autism. J Autism Dev Disord. 1988 Dec; 18(4):505-24. Lincoln AJ, Courchesne E, Kilman BA, Elmasian R, Allen M. PMID: 3215879.
      View in: PubMed   Mentions: 48     Fields:    Translation:Humans
    122. Visual memory processes in high-functioning individuals with autism. J Autism Dev Disord. 1988 Dec; 18(4):601-15. Ameli R, Courchesne E, Lincoln A, Kaufman AS, Grillon C. PMID: 3215886.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    123. Hypoplasia of cerebellar vermal lobules VI and VII in autism. N Engl J Med. 1988 May 26; 318(21):1349-54. Courchesne E, Yeung-Courchesne R, Press GA, Hesselink JR, Jernigan TL. PMID: 3367935.
      View in: PubMed   Mentions: 249     Fields:    Translation:Humans
    124. Hypothesis testing with principal components analysis: the dissociation of P3b and Nc. Electroencephalogr Clin Neurophysiol Suppl. 1987; 40:211-9. Lincoln AJ, Courchesne E, Elmasian R. PMID: 3319522.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    125. Increased amplitude of the auditory P2 and P3b components in adolescents with developmental dysphasia. Electroencephalogr Clin Neurophysiol Suppl. 1987; 40:577-83. Adams J, Courchesne E, Elmasian R, Lincoln A. PMID: 2446852.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
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