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Beyond the Spectrum: Subtype-Specific Molecular Insights into Autism Spectrum Disorder Via Multimodal Data Integration. medRxiv. 2024 Sep 23.
Zahiri J, Mirzaie M, Duan K, Xiao Y, Aamodt C, Yang X, Nazari S, Andreason C, Lopez L, Barnes CC, Arias S, Nalabolu S, Garmire L, Wang T, Hoekzema K, Eichler EE, Pierce K, Lewis NE, Courchesne E. PMID: 39399028; PMCID: PMC11469458.
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Differences in regional brain structure in toddlers with autism are related to future language outcomes. Nat Commun. 2024 Jun 13; 15(1):5075.
Duan K, Eyler L, Pierce K, Lombardo MV, Datko M, Hagler DJ, Taluja V, Zahiri J, Campbell K, Barnes CC, Arias S, Nalabolu S, Troxel J, Ji P, Courchesne E. PMID: 38871689; PMCID: PMC11176156.
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1 Fields:
Translation:
Humans
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Embryonic origin of two ASD subtypes of social symptom severity: the larger the brain cortical organoid size, the more severe the social symptoms. Mol Autism. 2024 05 25; 15(1):22.
Courchesne E, Taluja V, Nazari S, Aamodt CM, Pierce K, Duan K, Stophaeros S, Lopez L, Barnes CC, Troxel J, Campbell K, Wang T, Hoekzema K, Eichler EE, Nani JV, Pontes W, Sanchez SS, Lombardo MV, de Souza JS, Hayashi MAF, Muotri AR. PMID: 38790065; PMCID: PMC11127428.
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2 Fields:
Translation:
Humans
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Level of Attention to Motherese Speech as an Early Marker of Autism Spectrum Disorder. JAMA Netw Open. 2023 02 01; 6(2):e2255125.
Pierce K, Wen TH, Zahiri J, Andreason C, Courchesne E, Barnes CC, Lopez L, Arias SJ, Esquivel A, Cheng A. PMID: 36753277; PMCID: PMC9909502.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Examination of the impact of the Get SET Early program on equitable access to care within the screen-evaluate-treat chain in toddlers with autism spectrum disorder. Autism. 2023 08; 27(6):1790-1802.
Pham C, Bacon EC, Grzybowski A, Carter-Barnes C, Arias S, Xu R, Lopez L, Courchesne E, Pierce K. PMID: 36629055; PMCID: PMC10333446.
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Humans
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A predictive ensemble classifier for the gene expression diagnosis of ASD at ages 1 to 4 years. Mol Psychiatry. 2023 02; 28(2):822-833.
Bao B, Zahiri J, Gazestani VH, Lopez L, Xiao Y, Kim R, Wen TH, Chiang AWT, Nalabolu S, Pierce K, Robasky K, Wang T, Hoekzema K, Eichler EE, Lewis NE, Courchesne E. PMID: 36266569; PMCID: PMC9908553.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Publisher Correction: A phenotypic spectrum of autism is attributable to the combined effects of rare variants, polygenic risk and sex. Nat Genet. 2022 Aug; 54(8):1259.
Antaki D, Guevara J, Maihofer AX, Klein M, Gujral M, Grove J, Carey CE, Hong O, Arranz MJ, Hervas A, Corsello C, Vaux KK, Muotri AR, Iakoucheva LM, Courchesne E, Pierce K, Gleeson JG, Robinson EB, Nievergelt CM, Sebat J. PMID: 35768728.
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PubMed Mentions:
3 Fields:
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A phenotypic spectrum of autism is attributable to the combined effects of rare variants, polygenic risk and sex. Nat Genet. 2022 09; 54(9):1284-1292.
Antaki D, Guevara J, Maihofer AX, Klein M, Gujral M, Grove J, Carey CE, Hong O, Arranz MJ, Hervas A, Corsello C, Vaux KK, Muotri AR, Iakoucheva LM, Courchesne E, Pierce K, Gleeson JG, Robinson EB, Nievergelt CM, Sebat J. PMID: 35654974; PMCID: PMC9474668.
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PubMed Mentions:
72 Fields:
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Humans
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Large scale validation of an early-age eye-tracking biomarker of an autism spectrum disorder subtype. Sci Rep. 2022 03 11; 12(1):4253.
Wen TH, Cheng A, Andreason C, Zahiri J, Xiao Y, Xu R, Bao B, Courchesne E, Barnes CC, Arias SJ, Pierce K. PMID: 35277549; PMCID: PMC8917231.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Neural responses to affective speech, including motherese, map onto clinical and social eye tracking profiles in toddlers with ASD. Nat Hum Behav. 2022 03; 6(3):443-454.
Xiao Y, Wen TH, Kupis L, Eyler LT, Goel D, Vaux K, Lombardo MV, Lewis NE, Pierce K, Courchesne E. PMID: 34980898.
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PubMed Mentions:
14 Fields:
Translation:
Humans
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Development of a culturally and linguistically sensitive virtual reality educational platform to improve vaccine acceptance within a refugee population: the SHIFA community engagement-public health innovation programme. BMJ Open. 2021 09 14; 11(9):e051184.
Streuli S, Ibrahim N, Mohamed A, Sharma M, Esmailian M, Sezan I, Farrell C, Sawyer M, Meyer D, El-Maleh K, Thamman R, Marchetti A, Lincoln A, Courchesne E, Sahid A, Bhavnani SP. PMID: 34521673; PMCID: PMC8442061.
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PubMed Mentions:
6 Fields:
Translation:
HumansPHPublic Health
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Get SET Early to Identify and Treatment Refer Autism Spectrum Disorder at 1 Year and Discover Factors That Influence Early Diagnosis. J Pediatr. 2021 Sep; 236:179-188.
Pierce K, Gazestani V, Bacon E, Courchesne E, Cheng A, Barnes CC, Nalabolu S, Cha D, Arias S, Lopez L, Pham C, Gaines K, Gyurjyan G, Cook-Clark T, Karins K. PMID: 33915154.
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PubMed Mentions:
22 Fields:
Translation:
HumansPHPublic Health
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Multiple freeze-thaw cycles lead to a loss of consistency in poly(A)-enriched RNA sequencing. BMC Genomics. 2021 Jan 21; 22(1):69.
Kellman BP, Baghdassarian HM, Pramparo T, Shamie I, Gazestani V, Begzati A, Li S, Nalabolu S, Murray S, Lopez L, Pierce K, Courchesne E, Lewis NE. PMID: 33478392; PMCID: PMC7818915.
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PubMed Mentions:
11 Fields:
Translation:
HumansCells
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Prenatal Origins of ASD: The When, What, and How of ASD Development. Trends Neurosci. 2020 05; 43(5):326-342.
Courchesne E, Gazestani VH, Lewis NE. PMID: 32353336; PMCID: PMC7373219.
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PubMed Mentions:
68 Fields:
Translation:
Humans
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Identifying prognostic markers in autism spectrum disorder using eye tracking. Autism. 2020 04; 24(3):658-669.
Bacon EC, Moore A, Lee Q, Carter Barnes C, Courchesne E, Pierce K. PMID: 31647314; PMCID: PMC7166165.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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A perturbed gene network containing PI3K-AKT, RAS-ERK and WNT-β-catenin pathways in leukocytes is linked to ASD genetics and symptom severity. Nat Neurosci. 2019 10; 22(10):1624-1634.
Gazestani VH, Pramparo T, Nalabolu S, Kellman BP, Murray S, Lopez L, Pierce K, Courchesne E, Lewis NE. PMID: 31551593; PMCID: PMC6764590.
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PubMed Mentions:
45 Fields:
Translation:
HumansCells
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Evaluation of the Diagnostic Stability of the Early Autism Spectrum Disorder Phenotype in the General Population Starting at 12 Months. JAMA Pediatr. 2019 06 01; 173(6):578-587.
Pierce K, Gazestani VH, Bacon E, Barnes CC, Cha D, Nalabolu S, Lopez L, Moore A, Pence-Stophaeros S, Courchesne E. PMID: 31034004; PMCID: PMC6547081.
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The ASD Living Biology: from cell proliferation to clinical phenotype. Mol Psychiatry. 2019 01; 24(1):88-107.
Courchesne E, Pramparo T, Gazestani VH, Lombardo MV, Pierce K, Lewis NE. PMID: 29934544; PMCID: PMC6309606.
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PubMed Mentions:
103 Fields:
Translation:
HumansAnimals
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Naturalistic language sampling to characterize the language abilities of 3-year-olds with autism spectrum disorder. Autism. 2019 04; 23(3):699-712.
Bacon EC, Osuna S, Courchesne E, Pierce K. PMID: 29754501; PMCID: PMC6212344.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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Paternally inherited cis-regulatory structural variants are associated with autism. Science. 2018 04 20; 360(6386):327-331.
Brandler WM, Antaki D, Gujral M, Kleiber ML, Whitney J, Maile MS, Hong O, Chapman TR, Tan S, Tandon P, Pang T, Tang SC, Vaux KK, Yang Y, Harrington E, Juul S, Turner DJ, Thiruvahindrapuram B, Kaur G, Wang Z, Kingsmore SF, Gleeson JG, Bisson D, Kakaradov B, Telenti A, Venter JC, Corominas R, Toma C, Cormand B, Rueda I, Guijarro S, Messer KS, Nievergelt CM, Arranz MJ, Courchesne E, Pierce K, Muotri AR, Iakoucheva LM, Hervas A, Scherer SW, Corsello C, Sebat J. PMID: 29674594; PMCID: PMC6449150.
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102 Fields:
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HumansCells
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The geometric preference subtype in ASD: identifying a consistent, early-emerging phenomenon through eye tracking. Mol Autism. 2018; 9:19.
Moore A, Wozniak M, Yousef A, Barnes CC, Cha D, Courchesne E, Pierce K. PMID: 29581878; PMCID: PMC5861622.
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PubMed Mentions:
27 Fields:
Translation:
Humans
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Rethinking the idea of late autism spectrum disorder onset. Dev Psychopathol. 2018 05; 30(2):553-569.
Bacon EC, Courchesne E, Barnes CC, Cha D, Pence S, Schreibman L, Stahmer AC, Pierce K. PMID: 28803559; PMCID: PMC10515446.
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PubMed Mentions:
22 Translation:
Humans
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To Screen or Not to Screen Universally for Autism is not the Question: Why the Task Force Got It Wrong. J Pediatr. 2016 09; 176:182-94.
Pierce K, Courchesne E, Bacon E. PMID: 27421956; PMCID: PMC5679123.
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PubMed Mentions:
28 Fields:
Translation:
HumansPHPublic Health
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Frequency and Complexity of De Novo Structural Mutation in Autism. Am J Hum Genet. 2016 Apr 07; 98(4):667-79.
Brandler WM, Antaki D, Gujral M, Noor A, Rosanio G, Chapman TR, Barrera DJ, Lin GN, Malhotra D, Watts AC, Wong LC, Estabillo JA, Gadomski TE, Hong O, Fajardo KV, Bhandari A, Owen R, Baughn M, Yuan J, Solomon T, Moyzis AG, Maile MS, Sanders SJ, Reiner GE, Vaux KK, Strom CM, Zhang K, Muotri AR, Akshoomoff N, Leal SM, Pierce K, Courchesne E, Iakoucheva LM, Corsello C, Sebat J. PMID: 27018473; PMCID: PMC4833290.
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PubMed Mentions:
54 Fields:
Translation:
HumansCells
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Cell cycle networks link gene expression dysregulation, mutation, and brain maldevelopment in autistic toddlers. Mol Syst Biol. 2015 Dec 14; 11(12):841.
Pramparo T, Lombardo MV, Campbell K, Barnes CC, Marinero S, Solso S, Young J, Mayo M, Dale A, Ahrens-Barbeau C, Murray SS, Lopez L, Lewis N, Pierce K, Courchesne E. PMID: 26668231; PMCID: PMC4704485.
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PubMed Mentions:
42 Fields:
Translation:
Humans
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Diffusion Tensor Imaging Provides Evidence of Possible Axonal Overconnectivity in Frontal Lobes in Autism Spectrum Disorder Toddlers. Biol Psychiatry. 2016 Apr 15; 79(8):676-84.
Solso S, Xu R, Proudfoot J, Hagler DJ, Campbell K, Venkatraman V, Carter Barnes C, Ahrens-Barbeau C, Pierce K, Dale A, Eyler L, Courchesne E. PMID: 26300272; PMCID: PMC4699869.
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PubMed Mentions:
84 Fields:
Translation:
HumansCells
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Prediction of autism by translation and immune/inflammation coexpressed genes in toddlers from pediatric community practices. JAMA Psychiatry. 2015 Apr; 72(4):386-94.
Pramparo T, Pierce K, Lombardo MV, Carter Barnes C, Marinero S, Ahrens-Barbeau C, Murray SS, Lopez L, Xu R, Courchesne E. PMID: 25739104.
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PubMed Mentions:
52 Fields:
Translation:
HumansCells
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Patches of disorganization in the neocortex of children with autism. N Engl J Med. 2014 Mar 27; 370(13):1209-1219.
Stoner R, Chow ML, Boyle MP, Sunkin SM, Mouton PR, Roy S, Wynshaw-Boris A, Colamarino SA, Lein ES, Courchesne E. PMID: 24670167; PMCID: PMC4499461.
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PubMed Mentions:
340 Fields:
Translation:
HumansCells
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Measuring outcome in an early intervention program for toddlers with autism spectrum disorder: use of a curriculum-based assessment. Autism Res Treat. 2014; 2014:964704.
Bacon EC, Dufek S, Schreibman L, Stahmer AC, Pierce K, Courchesne E. PMID: 24711926; PMCID: PMC3966353.
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15
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Blood-based gene expression signatures of infants and toddlers with autism. J Am Acad Child Adolesc Psychiatry. 2012 Sep; 51(9):934-44.e2.
Glatt SJ, Tsuang MT, Winn M, Chandler SD, Collins M, Lopez L, Weinfeld M, Carter C, Schork N, Pierce K, Courchesne E. PMID: 22917206; PMCID: PMC3756503.
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PubMed Mentions:
50 Fields:
Translation:
HumansCells
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Abnormal microglial-neuronal spatial organization in the dorsolateral prefrontal cortex in autism. Brain Res. 2012 May 25; 1456:72-81.
Morgan JT, Chana G, Abramson I, Semendeferi K, Courchesne E, Everall IP. PMID: 22516109.
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PubMed Mentions:
96 Fields:
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HumansCells
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Age-dependent brain gene expression and copy number anomalies in autism suggest distinct pathological processes at young versus mature ages. PLoS Genet. 2012; 8(3):e1002592.
Chow ML, Pramparo T, Winn ME, Barnes CC, Li HR, Weiss L, Fan JB, Murray S, April C, Belinson H, Fu XD, Wynshaw-Boris A, Schork NJ, Courchesne E. PMID: 22457638; PMCID: PMC3310790.
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PubMed Mentions:
108 Fields:
Translation:
HumansCells
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Preprocessing and Quality Control Strategies for Illumina DASL Assay-Based Brain Gene Expression Studies with Semi-Degraded Samples. Front Genet. 2012; 3:11.
Chow ML, Winn ME, Li HR, April C, Wynshaw-Boris A, Fan JB, Fu XD, Courchesne E, Schork NJ. PMID: 22375143; PMCID: PMC3286152.
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PubMed Mentions:
14
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A failure of left temporal cortex to specialize for language is an early emerging and fundamental property of autism. Brain. 2012 Mar; 135(Pt 3):949-60.
Eyler LT, Pierce K, Courchesne E. PMID: 22350062; PMCID: PMC3286331.
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PubMed Mentions:
140 Fields:
Translation:
Humans
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Neuron number and size in prefrontal cortex of children with autism. JAMA. 2011 Nov 09; 306(18):2001-10.
Courchesne E, Mouton PR, Calhoun ME, Semendeferi K, Ahrens-Barbeau C, Hallet MJ, Barnes CC, Pierce K. PMID: 22068992.
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PubMed Mentions:
350 Fields:
Translation:
HumansCells
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Genome-wide expression assay comparison across frozen and fixed postmortem brain tissue samples. BMC Genomics. 2011 Sep 10; 12:449.
Chow ML, Li HR, Winn ME, April C, Barnes CC, Wynshaw-Boris A, Fan JB, Fu XD, Courchesne E, Schork NJ. PMID: 21906392; PMCID: PMC3179967.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Disrupted neural synchronization in toddlers with autism. Neuron. 2011 Jun 23; 70(6):1218-25.
Dinstein I, Pierce K, Eyler L, Solso S, Malach R, Behrmann M, Courchesne E. PMID: 21689606; PMCID: PMC3119852.
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PubMed Mentions:
179 Fields:
Translation:
HumansCells
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Brain growth across the life span in autism: age-specific changes in anatomical pathology. Brain Res. 2011 Mar 22; 1380:138-45.
Courchesne E, Campbell K, Solso S. PMID: 20920490; PMCID: PMC4500507.
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PubMed Mentions:
295 Fields:
Translation:
Humans
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Microglial activation and increased microglial density observed in the dorsolateral prefrontal cortex in autism. Biol Psychiatry. 2010 Aug 15; 68(4):368-76.
Morgan JT, Chana G, Pardo CA, Achim C, Semendeferi K, Buckwalter J, Courchesne E, Everall IP. PMID: 20674603.
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PubMed Mentions:
324 Fields:
Translation:
HumansCells
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Longitudinal magnetic resonance imaging study of cortical development through early childhood in autism. J Neurosci. 2010 Mar 24; 30(12):4419-27.
Schumann CM, Bloss CS, Barnes CC, Wideman GM, Carper RA, Akshoomoff N, Pierce K, Hagler D, Schork N, Lord C, Courchesne E. PMID: 20335478; PMCID: PMC2859218.
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PubMed Mentions:
265 Fields:
Translation:
Humans
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Amygdala enlargement in toddlers with autism related to severity of social and communication impairments. Biol Psychiatry. 2009 Nov 15; 66(10):942-9.
Schumann CM, Barnes CC, Lord C, Courchesne E. PMID: 19726029; PMCID: PMC2795360.
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PubMed Mentions:
141 Fields:
Translation:
Humans
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Deviant functional magnetic resonance imaging patterns of brain activity to speech in 2-3-year-old children with autism spectrum disorder. Biol Psychiatry. 2008 Oct 01; 64(7):589-98.
Redcay E, Courchesne E. PMID: 18672231; PMCID: PMC2879340.
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PubMed Mentions:
108 Fields:
Translation:
Humans
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Functional abnormalities of the default network during self- and other-reflection in autism. Soc Cogn Affect Neurosci. 2008 Jun; 3(2):177-90.
Kennedy DP, Courchesne E. PMID: 19015108; PMCID: PMC2555458.
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PubMed Mentions:
113 Fields:
Translation:
Humans
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Functional neuroimaging of speech perception during a pivotal period in language acquisition. Dev Sci. 2008 Mar; 11(2):237-52.
Redcay E, Haist F, Courchesne E. PMID: 18333980.
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PubMed Mentions:
53 Fields:
Translation:
Humans
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The intrinsic functional organization of the brain is altered in autism. Neuroimage. 2008 Feb 15; 39(4):1877-85.
Kennedy DP, Courchesne E. PMID: 18083565.
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PubMed Mentions:
250 Fields:
Translation:
Humans
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Mapping early brain development in autism. Neuron. 2007 Oct 25; 56(2):399-413.
Courchesne E, Pierce K, Schumann CM, Redcay E, Buckwalter JA, Kennedy DP, Morgan J. PMID: 17964254.
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PubMed Mentions:
369 Fields:
Translation:
HumansCells
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fMRI during natural sleep as a method to study brain function during early childhood. Neuroimage. 2007 Dec; 38(4):696-707.
Redcay E, Kennedy DP, Courchesne E. PMID: 17904385.
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PubMed Mentions:
45 Fields:
Translation:
Humans
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Abnormalities on the neurological examination and EEG in young children with pervasive developmental disorders. J Autism Dev Disord. 2007 May; 37(5):887-93.
Akshoomoff N, Farid N, Courchesne E, Haas R. PMID: 17048091; PMCID: PMC2094050.
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PubMed Mentions:
15 Fields:
Translation:
Humans
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MRI neuroanatomy in young girls with autism: a preliminary study. J Am Acad Child Adolesc Psychiatry. 2007 Apr; 46(4):515-523.
Bloss CS, Courchesne E. PMID: 17420687.
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PubMed Mentions:
60 Fields:
Translation:
Humans
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No reduction of spindle neuron number in frontoinsular cortex in autism. Brain Cogn. 2007 Jul; 64(2):124-9.
Kennedy DP, Semendeferi K, Courchesne E. PMID: 17353073.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Failing to deactivate: resting functional abnormalities in autism. Proc Natl Acad Sci U S A. 2006 May 23; 103(21):8275-80.
Kennedy DP, Redcay E, Courchesne E. PMID: 16702548; PMCID: PMC1472462.
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PubMed Mentions:
257 Fields:
Translation:
Humans
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When is the brain enlarged in autism? A meta-analysis of all brain size reports. Biol Psychiatry. 2005 Jul 01; 58(1):1-9.
Redcay E, Courchesne E. PMID: 15935993.
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PubMed Mentions:
227 Fields:
Translation:
Humans
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Brain overgrowth in autism during a critical time in development: implications for frontal pyramidal neuron and interneuron development and connectivity. Int J Dev Neurosci. 2005 Apr-May; 23(2-3):153-70.
Courchesne E, Pierce K. PMID: 15749242.
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PubMed Mentions:
147 Fields:
Translation:
HumansCells
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Why the frontal cortex in autism might be talking only to itself: local over-connectivity but long-distance disconnection. Curr Opin Neurobiol. 2005 Apr; 15(2):225-30.
Courchesne E, Pierce K. PMID: 15831407.
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PubMed Mentions:
407 Fields:
Translation:
Humans
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Localized enlargement of the frontal cortex in early autism. Biol Psychiatry. 2005 Jan 15; 57(2):126-33.
Carper RA, Courchesne E. PMID: 15652870.
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PubMed Mentions:
170 Fields:
Translation:
HumansCTClinical Trials
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Auditory spatial localization and attention deficits in autistic adults. Brain Res Cogn Brain Res. 2005 May; 23(2-3):221-34.
Teder-Sälejärvi WA, Pierce KL, Courchesne E, Hillyard SA. PMID: 15820630.
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PubMed Mentions:
41 Fields:
Translation:
Humans
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Autism at the beginning: microstructural and growth abnormalities underlying the cognitive and behavioral phenotype of autism. Dev Psychopathol. 2005; 17(3):577-97.
Courchesne E, Redcay E, Morgan JT, Kennedy DP. PMID: 16262983.
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PubMed Mentions:
77 Translation:
HumansCells
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The functional neuroanatomy of spatial attention in autism spectrum disorder. Dev Neuropsychol. 2005; 27(3):425-58.
Haist F, Adamo M, Westerfield M, Courchesne E, Townsend J. PMID: 15843105.
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PubMed Mentions:
29 Fields:
Translation:
Humans
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The brain response to personally familiar faces in autism: findings of fusiform activity and beyond. Brain. 2004 Dec; 127(Pt 12):2703-16.
Pierce K, Haist F, Sedaghat F, Courchesne E. PMID: 15319275.
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PubMed Mentions:
165 Fields:
Translation:
Humans
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The autistic brain: birth through adulthood. Curr Opin Neurol. 2004 Aug; 17(4):489-96.
Courchesne E, Redcay E, Kennedy DP. PMID: 15247547.
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PubMed Mentions:
56 Fields:
Translation:
Humans
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Electroencephalographic brain dynamics following manually responded visual targets. PLoS Biol. 2004 Jun; 2(6):e176.
Makeig S, Delorme A, Westerfield M, Jung TP, Townsend J, Courchesne E, Sejnowski TJ. PMID: 15208723; PMCID: PMC423146.
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PubMed Mentions:
132 Fields:
Translation:
Humans
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Outcome classification of preschool children with autism spectrum disorders using MRI brain measures. J Am Acad Child Adolesc Psychiatry. 2004 Mar; 43(3):349-57.
Akshoomoff N, Lord C, Lincoln AJ, Courchesne RY, Carper RA, Townsend J, Courchesne E. PMID: 15076269.
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PubMed Mentions:
54 Fields:
Translation:
Humans
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Brain development in autism: early overgrowth followed by premature arrest of growth. Ment Retard Dev Disabil Res Rev. 2004; 10(2):106-11.
Courchesne E. PMID: 15362165.
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PubMed Mentions:
118 Fields:
Translation:
Humans
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Abnormal variability and distribution of functional maps in autism: an FMRI study of visuomotor learning. Am J Psychiatry. 2003 Oct; 160(10):1847-62.
Müller RA, Kleinhans N, Kemmotsu N, Pierce K, Courchesne E. PMID: 14514501.
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PubMed Mentions:
72 Fields:
Translation:
Humans
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Evidence of brain overgrowth in the first year of life in autism. JAMA. 2003 Jul 16; 290(3):337-44.
Courchesne E, Carper R, Akshoomoff N. PMID: 12865374.
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PubMed Mentions:
356 Fields:
Translation:
Humans
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Differential effects of developmental cerebellar abnormality on cognitive and motor functions in the cerebellum: an fMRI study of autism. Am J Psychiatry. 2003 Feb; 160(2):262-73.
Allen G, Courchesne E. PMID: 12562572.
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PubMed Mentions:
109 Fields:
Translation:
Humans
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Cerebellar abnormalities in infants and toddlers with Williams syndrome. Dev Med Child Neurol. 2002 Oct; 44(10):688-94.
Jones W, Hesselink J, Courchesne E, Duncan T, Matsuda K, Bellugi U. PMID: 12418794.
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PubMed Mentions:
17 Fields:
Translation:
Humans
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Relationship between head circumference and brain volume in healthy normal toddlers, children, and adults. Neuropediatrics. 2002 Oct; 33(5):239-41.
Bartholomeusz HH, Courchesne E, Karns CM. PMID: 12536365.
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PubMed Mentions:
106 Fields:
Translation:
Humans
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Cerebral lobes in autism: early hyperplasia and abnormal age effects. Neuroimage. 2002 Aug; 16(4):1038-51.
Carper RA, Moses P, Tigue ZD, Courchesne E. PMID: 12202091.
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PubMed Mentions:
205 Fields:
Translation:
Humans
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Dynamic brain sources of visual evoked responses. Science. 2002 Jan 25; 295(5555):690-4.
Makeig S, Westerfield M, Jung TP, Enghoff S, Townsend J, Courchesne E, Sejnowski TJ. PMID: 11809976.
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PubMed Mentions:
445 Fields:
Translation:
Humans
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Abnormal early brain development in autism. Mol Psychiatry. 2002; 7 Suppl 2:S21-3.
Courchesne E. PMID: 12142938.
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PubMed Mentions:
53 Fields:
Translation:
Humans
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The neurobiological basis of autism from a developmental perspective. Dev Psychopathol. 2002; 14(3):613-34.
Akshoomoff N, Pierce K, Courchesne E. PMID: 12349876.
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23 Translation:
Humans
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Analysis and visualization of single-trial event-related potentials. Hum Brain Mapp. 2001 Nov; 14(3):166-85.
Jung TP, Makeig S, Westerfield M, Townsend J, Courchesne E, Sejnowski TJ. PMID: 11559961; PMCID: PMC6871967.
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162 Fields:
Translation:
Humans
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Face processing occurs outside the fusiform 'face area' in autism: evidence from functional MRI. Brain. 2001 Oct; 124(Pt 10):2059-73.
Pierce K, Müller RA, Ambrose J, Allen G, Courchesne E. PMID: 11571222.
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PubMed Mentions:
272 Fields:
Translation:
Humans
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Unusual brain growth patterns in early life in patients with autistic disorder: an MRI study. Neurology. 2001 Jul 24; 57(2):245-54.
Courchesne E, Karns CM, Davis HR, Ziccardi R, Carper RA, Tigue ZD, Chisum HJ, Moses P, Pierce K, Lord C, Lincoln AJ, Pizzo S, Schreibman L, Haas RH, Akshoomoff NA, Courchesne RY. PMID: 11468308.
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PubMed Mentions:
521 Fields:
Translation:
Humans
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Prenatal, perinatal, and neonatal factors in autism, pervasive developmental disorder-not otherwise specified, and the general population. Pediatrics. 2001 Apr; 107(4):E63.
Juul-Dam N, Townsend J, Courchesne E. PMID: 11335784.
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PubMed Mentions:
60 Fields:
Translation:
Humans
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Event-related brain response abnormalities in autism: evidence for impaired cerebello-frontal spatial attention networks. Brain Res Cogn Brain Res. 2001 Mar; 11(1):127-45.
Townsend J, Westerfield M, Leaver E, Makeig S, Jung T, Pierce K, Courchesne E. PMID: 11240116.
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PubMed Mentions:
45 Fields:
Translation:
HumansCTClinical Trials
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Attention function and dysfunction in autism. Front Biosci. 2001 Feb 01; 6:D105-19.
Allen G, Courchesne E. PMID: 11171544.
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PubMed Mentions:
85 Fields:
Translation:
Humans
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Broca's area and the discrimination of frequency transitions: a functional MRI study. Brain Lang. 2001 Jan; 76(1):70-6.
Müller RA, Kleinhans N, Courchesne E. PMID: 11161356.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Regional size reduction in the human corpus callosum following pre- and perinatal brain injury. Cereb Cortex. 2000 Dec; 10(12):1200-10.
Moses P, Courchesne E, Stiles J, Trauner D, Egaas B, Edwards E. PMID: 11073869.
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PubMed Mentions:
23 Fields:
Translation:
Humans
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Removal of eye activity artifacts from visual event-related potentials in normal and clinical subjects. Clin Neurophysiol. 2000 Oct; 111(10):1745-58.
Jung TP, Makeig S, Westerfield M, Townsend J, Courchesne E, Sejnowski TJ. PMID: 11018488.
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PubMed Mentions:
397 Fields:
Translation:
Humans
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Normal brain development and aging: quantitative analysis at in vivo MR imaging in healthy volunteers. Radiology. 2000 Sep; 216(3):672-82.
Courchesne E, Chisum HJ, Townsend J, Cowles A, Covington J, Egaas B, Harwood M, Hinds S, Press GA. PMID: 10966694.
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PubMed Mentions:
388 Fields:
Translation:
Humans
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Inverse correlation between frontal lobe and cerebellum sizes in children with autism. Brain. 2000 Apr; 123 ( Pt 4):836-44.
Carper RA, Courchesne E. PMID: 10734014.
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PubMed Mentions:
84 Fields:
Translation:
Humans
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Exploring the neurofunctional organization of face processing in autism. Arch Gen Psychiatry. 2000 Apr; 57(4):344-6.
Pierce K, Courchesne E. PMID: 10768695.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Spatial attention deficits in patients with acquired or developmental cerebellar abnormality. J Neurosci. 1999 Jul 01; 19(13):5632-43.
Townsend J, Courchesne E, Covington J, Westerfield M, Harris NS, Lyden P, Lowry TP, Press GA. PMID: 10377369; PMCID: PMC6782343.
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PubMed Mentions:
73 Fields:
Translation:
Humans
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Neuroanatomic contributions to slowed orienting of attention in children with autism. Brain Res Cogn Brain Res. 1999 May; 8(1):61-71.
Harris NS, Courchesne E, Townsend J, Carper RA, Lord C. PMID: 10216274.
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PubMed Mentions:
45 Fields:
Translation:
Humans
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Brain weight in autism: normal in the majority of cases, megalencephalic in rare cases. Neurology. 1999 Mar 23; 52(5):1057-9.
Courchesne E, Müller RA, Saitoh O. PMID: 10102428.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Prediction and preparation, fundamental functions of the cerebellum. Learn Mem. 1997 May-Jun; 4(1):1-35.
Courchesne E, Allen G. PMID: 10456051.
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PubMed Mentions:
65 Fields:
Translation:
HumansAnimals
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Brainstem, cerebellar and limbic neuroanatomical abnormalities in autism. Curr Opin Neurobiol. 1997 Apr; 7(2):269-78.
Courchesne E. PMID: 9142760.
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PubMed Mentions:
101 Fields:
Translation:
Humans
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Attentional activation of the cerebellum independent of motor involvement. Science. 1997 Mar 28; 275(5308):1940-3.
Allen G, Buxton RB, Wong EC, Courchesne E. PMID: 9072973.
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PubMed Mentions:
200 Fields:
Translation:
Humans
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Visual attention abnormalities in autism: delayed orienting to location. J Int Neuropsychol Soc. 1996 Nov; 2(6):541-50.
Townsend J, Harris NS, Courchesne E. PMID: 9375158.
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PubMed Mentions:
48 Fields:
Translation:
Humans
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Neurologic abnormalities in infantile autism. J Child Neurol. 1996 Mar; 11(2):84-92.
Haas RH, Townsend J, Courchesne E, Lincoln AJ, Schreibman L, Yeung-Courchesne R. PMID: 8881982.
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PubMed Mentions:
25 Fields:
Translation:
Humans
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Sensory modulation of auditory stimuli in children with autism and receptive developmental language disorder: event-related brain potential evidence. J Autism Dev Disord. 1995 Oct; 25(5):521-39.
Lincoln AJ, Courchesne E, Harms L, Allen M. PMID: 8567597.
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PubMed Mentions:
24 Fields:
Translation:
Humans
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Reduced size of corpus callosum in autism. Arch Neurol. 1995 Aug; 52(8):794-801.
Egaas B, Courchesne E, Saitoh O. PMID: 7639631.
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PubMed Mentions:
107 Fields:
Translation:
Humans
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NMR intensity of corpus callosum differs with age but not with diagnosis of autism. Neuroreport. 1995 Jun 19; 6(9):1253-6.
Belmonte M, Egaas B, Townsend J, Courchesne E. PMID: 7669980.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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New evidence of cerebellar and brainstem hypoplasia in autistic infants, children and adolescents: the MR imaging study by Hashimoto and colleagues. J Autism Dev Disord. 1995 Feb; 25(1):19-22.
Courchesne E. PMID: 7608031.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Cross-sectional area of the posterior hippocampus in autistic patients with cerebellar and corpus callosum abnormalities. Neurology. 1995 Feb; 45(2):317-24.
Saitoh O, Courchesne E, Egaas B, Lincoln AJ, Schreibman L. PMID: 7854533.
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A model system for the study of attention and the cerebellum: infantile autism. Electroencephalogr Clin Neurophysiol Suppl. 1995; 44:315-25.
Courchesne E, Akshoomoff NA, Townsend J, Saitoh O. PMID: 7649039.
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PubMed Mentions:
5 Fields:
Translation:
Humans
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Impairment in shifting attention in autistic and cerebellar patients. Behav Neurosci. 1994 Oct; 108(5):848-65.
Courchesne E, Townsend J, Akshoomoff NA, Saitoh O, Yeung-Courchesne R, Lincoln AJ, James HE, Haas RH, Schreibman L, Lau L. PMID: 7826509.
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PubMed Mentions:
156 Fields:
Translation:
Humans
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The brain in infantile autism: posterior fossa structures are abnormal. Neurology. 1994 Feb; 44(2):214-23.
Courchesne E, Townsend J, Saitoh O. PMID: 8309561.
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PubMed Mentions:
50 Fields:
Translation:
Humans
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Abnormality of cerebellar vermian lobules VI and VII in patients with infantile autism: identification of hypoplastic and hyperplastic subgroups with MR imaging. AJR Am J Roentgenol. 1994 Jan; 162(1):123-30.
Courchesne E, Saitoh O, Yeung-Courchesne R, Press GA, Lincoln AJ, Haas RH, Schreibman L. PMID: 8273650.
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PubMed Mentions:
64 Fields:
Translation:
Humans
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Contextual probability evaluation in autistic, receptive developmental language disorder, and control children: event-related brain potential evidence. J Autism Dev Disord. 1993 Mar; 23(1):37-58.
Lincoln AJ, Courchesne E, Harms L, Allen M. PMID: 8463201.
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PubMed Mentions:
23 Fields:
Translation:
Humans
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Parietal lobe abnormalities detected with MR in patients with infantile autism. AJR Am J Roentgenol. 1993 Feb; 160(2):387-93.
Courchesne E, Press GA, Yeung-Courchesne R. PMID: 8424359.
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PubMed Mentions:
42 Fields:
Translation:
Humans
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Auditory processing abilities in non-retarded adolescents and young adults with developmental receptive language disorder and autism. Brain Lang. 1992 Nov; 43(4):613-22.
Lincoln AJ, Dickstein P, Courchesne E, Elmasian R, Tallal P. PMID: 1483193.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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A new role for the cerebellum in cognitive operations. Behav Neurosci. 1992 Oct; 106(5):731-8.
Akshoomoff NA, Courchesne E. PMID: 1445653.
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PubMed Mentions:
57 Fields:
Translation:
Humans
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In vivo myeloarchitectonic analysis of human striate and extrastriate cortex using magnetic resonance imaging. Cereb Cortex. 1992 Sep-Oct; 2(5):417-24.
Clark VP, Courchesne E, Grafe M. PMID: 1422094.
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PubMed Mentions:
57 Fields:
Translation:
HumansCells
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Cerebellar and cerebral abnormalities in Rett syndrome: a quantitative MR analysis. AJR Am J Roentgenol. 1992 Jul; 159(1):177-83.
Murakami JW, Courchesne E, Haas RH, Press GA, Yeung-Courchesne R. PMID: 1609693.
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PubMed Mentions:
33 Fields:
Translation:
Humans
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Contribution of the cerebellum to neuropsychological functioning: evidence from a case of cerebellar degenerative disorder. Neuropsychologia. 1992 Apr; 30(4):315-28.
Akshoomoff NA, Courchesne E, Press GA, Iragui V. PMID: 1603296.
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PubMed Mentions:
17 Fields:
Translation:
Humans
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Autism. New Dir Ment Health Serv. 1992; (54):19-23.
Courchesne E. PMID: 1625655.
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PubMed Mentions: Fields:
Translation:
Humans
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Absence of magnetic resonance imaging evidence of pontine abnormality in infantile autism. Arch Neurol. 1991 Nov; 48(11):1160-3.
Hsu M, Yeung-Courchesne R, Courchesne E, Press GA. PMID: 1953402.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Neuroanatomic imaging in autism. Pediatrics. 1991 May; 87(5 Pt 2):781-90.
Courchesne E. PMID: 2020537.
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PubMed Mentions:
29 Fields:
Translation:
Humans
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The cerebellum: 3. Anatomic-MR correlation in the coronal plane. AJR Am J Roentgenol. 1990 Mar; 154(3):593-602.
Press GA, Murakami JW, Courchesne E, Grafe M, Hesselink JR. PMID: 2106226.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Effects of focused selective attention tasks on event-related potentials in autistic and normal individuals. Electroencephalogr Clin Neurophysiol. 1990 Mar; 75(3):207-20.
Ciesielski KT, Courchesne E, Elmasian R. PMID: 1689644.
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PubMed Mentions:
52 Fields:
Translation:
Humans
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The cerebellum: 3. Anatomic-MR correlation in the coronal plane. AJNR Am J Neuroradiol. 1990 Jan-Feb; 11(1):41-50.
Press GA, Murakami JW, Courchesne E, Grafe M, Hesselink JR. PMID: 2105616; PMCID: PMC8332497.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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The cerebellum in sagittal plane--anatomic-MR correlation: 1. The vermis. AJR Am J Roentgenol. 1989 Oct; 153(4):829-35.
Courchesne E, Press GA, Murakami J, Berthoty D, Grafe M, Wiley CA, Hesselink JR. PMID: 2773740.
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PubMed Mentions:
24 Fields:
Translation:
Humans
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The cerebellum in sagittal plane--anatomic-MR correlation: 2. The cerebellar hemispheres. AJR Am J Roentgenol. 1989 Oct; 153(4):837-46.
Press GA, Murakami J, Courchesne E, Berthoty DP, Grafe M, Wiley CA, Hesselink JR. PMID: 2773741.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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Brainstem auditory evoked potentials in receptive developmental language disorder. Brain Lang. 1989 Oct; 37(3):409-18.
Akshoomoff N, Courchesne E, Yeung-Courchesne R, Costello J. PMID: 2804621.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Reduced cerebellar hemisphere size and its relationship to vermal hypoplasia in autism. Arch Neurol. 1989 Jun; 46(6):689-94.
Murakami JW, Courchesne E, Press GA, Yeung-Courchesne R, Hesselink JR. PMID: 2730382.
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PubMed Mentions:
46 Fields:
Translation:
Humans
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Brainstem and middle latency auditory evoked potentials in autism and developmental language disorder. J Autism Dev Disord. 1989 Jun; 19(2):255-69.
Grillon C, Courchesne E, Akshoomoff N. PMID: 2745391.
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PubMed Mentions:
18 Fields:
Translation:
Humans
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Pathophysiologic findings in nonretarded autism and receptive developmental language disorder. J Autism Dev Disord. 1989 Mar; 19(1):1-17.
Courchesne E, Lincoln AJ, Yeung-Courchesne R, Elmasian R, Grillon C. PMID: 2708293.
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PubMed Mentions:
44 Fields:
Translation:
Humans
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A study of intellectual abilities in high-functioning people with autism. J Autism Dev Disord. 1988 Dec; 18(4):505-24.
Lincoln AJ, Courchesne E, Kilman BA, Elmasian R, Allen M. PMID: 3215879.
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PubMed Mentions:
48 Fields:
Translation:
Humans
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Visual memory processes in high-functioning individuals with autism. J Autism Dev Disord. 1988 Dec; 18(4):601-15.
Ameli R, Courchesne E, Lincoln A, Kaufman AS, Grillon C. PMID: 3215886.
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PubMed Mentions:
22 Fields:
Translation:
Humans
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Hypoplasia of cerebellar vermal lobules VI and VII in autism. N Engl J Med. 1988 May 26; 318(21):1349-54.
Courchesne E, Yeung-Courchesne R, Press GA, Hesselink JR, Jernigan TL. PMID: 3367935.
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PubMed Mentions:
249 Fields:
Translation:
Humans
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Hypothesis testing with principal components analysis: the dissociation of P3b and Nc. Electroencephalogr Clin Neurophysiol Suppl. 1987; 40:211-9.
Lincoln AJ, Courchesne E, Elmasian R. PMID: 3319522.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Increased amplitude of the auditory P2 and P3b components in adolescents with developmental dysphasia. Electroencephalogr Clin Neurophysiol Suppl. 1987; 40:577-83.
Adams J, Courchesne E, Elmasian R, Lincoln A. PMID: 2446852.
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PubMed Mentions:
4 Fields:
Translation:
Humans