Nan Hao

Title(s)Professor, Molecular Biology
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
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    Systems biology analysis of RNA-binding protein aggregation during cellular aging
    NIH R01AG068112Sep 15, 2021 - May 31, 2026
    Role: Principal Investigator
    Systems Biology analysis of RNA-binding protein aggregation during cellular aging
    NIH R56AG068112Sep 15, 2020 - Aug 31, 2021
    Role: Principal Investigator
    Network-Driven Dynamics of Replicative Aging
    NIH R01AG056440Aug 1, 2017 - May 31, 2022
    Role: Principal Investigator
    Dynamically compartmentalized control of gene expression by messenger ribonucleoprotein granules
    NIH R01GM111458Aug 15, 2014 - Jun 30, 2023
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. Proc Natl Acad Sci U S A. 2024 Jan 16; 121(3):e2314245121. Sarsam RD, Xu J, Lahiri I, Gong W, Li Q, Oh J, Zhou Z, Hou P, Chong J, Hao N, Li S, Wang D, Leschziner AE. PMID: 38194460; PMCID: PMC10801861.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    2. A Standardized Set of MoClo-Compatible Inducible Promoter Systems for Tunable Gene Expression in Yeast. ACS Synth Biol. 2024 Jan 19; 13(1):85-102. O'Laughlin R, Tran Q, Lezia A, Ngamkanjanarat W, Emmanuele P, Hao N, Hasty J. PMID: 38079574.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    3. A Microfluidic Platform for Screening Gene Expression Dynamics across Yeast Strain Libraries. Bio Protoc. 2023 Nov 20; 13(22):e4883. Stasiowski E, O'Laughlin R, Holness S, Csicsery N, Hasty J, Hao N. PMID: 38023791; PMCID: PMC10665637.
      View in: PubMed   Mentions:
    4. Quantifying dynamic pro-inflammatory gene expression and heterogeneity in single macrophage cells. J Biol Chem. 2023 Oct; 299(10):105230. Naigles B, Narla AV, Soroczynski J, Tsimring LS, Hao N. PMID: 37689116; PMCID: PMC10579967.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    5. Fabrication of Microfluidic Devices for Continuously Monitoring Yeast Aging. Bio Protoc. 2023 Aug 05; 13(15):e4782. O'Laughlin R, Forrest E, Hasty J, Hao N. PMID: 37575396; PMCID: PMC10415209.
      View in: PubMed   Mentions: 1  
    6. Enhanced cellular longevity arising from environmental fluctuations. bioRxiv. 2023 Jul 07. Liu Y, Zhou Z, Wu S, Ni G, Zhang A, Tsimring LS, Hasty J, Hao N. PMID: 37461504; PMCID: PMC10350066.
      View in: PubMed   Mentions:
    7. Engineering longevity-design of a synthetic gene oscillator to slow cellular aging. Science. 2023 04 28; 380(6643):376-381. Zhou Z, Liu Y, Feng Y, Klepin S, Tsimring LS, Pillus L, Hasty J, Hao N. PMID: 37104589; PMCID: PMC10249776.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    8. Quantitative cell imaging approaches to metastatic state profiling. Front Cell Dev Biol. 2022; 10:1048630. Nevarez AJ, Hao N. PMID: 36393865; PMCID: PMC9640958.
      View in: PubMed   Mentions: 2  
    9. 3D printing a biocompatible elastomer for modeling muscle regeneration after volumetric muscle loss. Biomater Adv. 2022 Nov; 142:213171. Kiratitanaporn W, Berry DB, Mudla A, Fried T, Lao A, Yu C, Hao N, Ward SR, Chen S. PMID: 36341746.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    10. Age-dependent aggregation of ribosomal RNA-binding proteins links deterioration in chromatin stability with challenges to proteostasis. Elife. 2022 Oct 04; 11. Paxman J, Zhou Z, O'Laughlin R, Liu Y, Li Y, Tian W, Su H, Jiang Y, Holness SE, Stasiowski E, Tsimring LS, Pillus L, Hasty J, Hao N. PMID: 36194205; PMCID: PMC9578700.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    11. Memorizing environmental signals through feedback and feedforward loops. Curr Opin Cell Biol. 2021 04; 69:96-102. Jiang Y, Hao N. PMID: 33549848; PMCID: PMC8058236.
      View in: PubMed   Mentions: 12     Fields:    
    12. Cell-cycle-gated feedback control mediates desensitization to interferon stimulation. Elife. 2020 09 18; 9. Mudla A, Jiang Y, Arimoto KI, Xu B, Rajesh A, Ryan AP, Wang W, Daugherty MD, Zhang DE, Hao N. PMID: 32945770; PMCID: PMC7500952.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    13. A programmable fate decision landscape underlies single-cell aging in yeast. Science. 2020 Jul 17; 369(6501):325-329. Li Y, Jiang Y, Paxman J, O'Laughlin R, Klepin S, Zhu Y, Pillus L, Tsimring LS, Hasty J, Hao N. PMID: 32675375; PMCID: PMC7437498.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    14. A protein kinase A-regulated network encodes short- and long-lived cellular memories. Sci Signal. 2020 05 19; 13(632). Jiang Y, AkhavanAghdam Z, Li Y, Zid BM, Hao N. PMID: 32430291; PMCID: PMC7302112.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    15. Advances in quantitative biology methods for studying replicative aging in Saccharomyces cerevisiae. Transl Med Aging. 2020; 4:151-160. O'Laughlin R, Jin M, Li Y, Pillus L, Tsimring LS, Hasty J, Hao N. PMID: 33880425; PMCID: PMC8054985.
      View in: PubMed   Mentions: 8  
    16. Divergent Aging of Isogenic Yeast Cells Revealed through Single-Cell Phenotypic Dynamics. Cell Syst. 2019 03 27; 8(3):242-253.e3. Jin M, Li Y, O'Laughlin R, Bittihn P, Pillus L, Tsimring LS, Hasty J, Hao N. PMID: 30852250; PMCID: PMC6514117.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    17. Mitogen-activated protein kinase (MAPK) dynamics determine cell fate in the yeast mating response. J Biol Chem. 2017 12 15; 292(50):20354-20361. Li Y, Roberts J, AkhavanAghdam Z, Hao N. PMID: 29123025; PMCID: PMC5733576.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    18. Multigenerational silencing dynamics control cell aging. Proc Natl Acad Sci U S A. 2017 10 17; 114(42):11253-11258. Li Y, Jin M, O'Laughlin R, Bittihn P, Tsimring LS, Pillus L, Hasty J, Hao N. PMID: 29073021; PMCID: PMC5651738.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    19. Dynamic control of gene regulatory logic by seemingly redundant transcription factors. Elife. 2016 09 30; 5. AkhavanAghdam Z, Sinha J, Tabbaa OP, Hao N. PMID: 27690227; PMCID: PMC5047750.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
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