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Gourisankar Ghosh

Title(s)Professor, Chemistry and Biochemistry
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse research activities and funding
    The Role of Chromogranin A in Tauopathy
    NIH R21AG072487May 1, 2021 - Apr 30, 2023
    Role: Principal Investigator
    ASF/SF2: Phosphorylation and RNA Binding
    NIH R01GM084277Aug 10, 2009 - Jul 31, 2013
    Role: Principal Investigator
    Cofactor-Mediated DNA Binding by the NF-kappaB Dimers
    NIH R01GM085490Jul 1, 2009 - Mar 31, 2024
    Role: Principal Investigator
    IKK:Biophysical basis of dynamic regulation
    NIH R01CA141722Jul 1, 2009 - May 31, 2015
    Role: Principal Investigator
    IkB/NF-kB Recognition in Silico, In Vitro and In Vivo
    NIH P01GM071862Apr 7, 2006 - Feb 28, 2018
    Role: Co-Investigator
    NF-kB regulation by p105 and p100
    NIH R01AI064326Feb 15, 2005 - Apr 30, 2016
    Role: Principal Investigator
    MECHANISM OF TRANSCRIPTIONAL INHIBITION BY IKB PROTEINS
    NIH R01CA078749Apr 1, 1999 - Mar 31, 2003
    Role: Principal Investigator
    Structure/Function Studies of Nuclear FActor KB
    NIH R01CA071871Sep 5, 1996 - Oct 31, 2006
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. F2,6BP restores mitochondrial genome integrity in Huntington's disease. J Biol Chem. 2026 Mar; 302(3):111156. Chakraborty A, Mandal SM, Mankevich M, Mani RS, Shahabi S, Kodavati M, Sreenivasmurthy SG, Tapryal N, Hamilton DJ, Krishnan B, Hegde ML, Weinfeld M, Ghosh G, Hazra T. PMID: 41534834; PMCID: PMC12919243.
      View in: PubMed   Mentions:    Fields:    
    2. Teamwork of clustered low-affinity κB sites and accessory factors regulates transcriptional strength of NF-κB RelA dimers. Nucleic Acids Res. 2025 Sep 23; 53(18). Shahabi S, Biswas T, Shen Y, Sanahmadi R, Zou Y, Ghosh G. PMID: 41063342; PMCID: PMC12507517.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    3. The transcription complex p52-ETS1 is essential for germinal center formation. Nat Immunol. 2025 Sep; 26(9):1553-1566. Morgan D, Zhang B, Fidan K, Pan W, Vaiyapuri TS, Raju A, Hei D, See TY, Sari IN, Chan JW, Majee P, Balachander A, Yu J, Wong AH, Mok MMH, Foo SH, Tang WL, Ang N, Tan I, Peng YF, Jaynes P, Xu S, Ghosh G, Shahabi S, Jeyasekharan AD, Ikawa M, Zhang Y, Howland SW, Lau MC, Wang VY, Lam KP, Tergaonkar V. PMID: 40715659.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    4. Dual-specific autophosphorylation of kinase IKK2 enables phosphorylation of substrate IκBα through a phosphoenzyme intermediate. Elife. 2025 Jun 30; 13. Borar P, Biswas T, Chaudhuri A, Rao PT, Raychaudhuri S, Huxford T, Chakrabarti S, Ghosh G, Polley S. PMID: 40586777; PMCID: PMC12208667.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    5. F2,6BP restores mitochondrial genome integrity in Huntington's Disease. bioRxiv. 2025 Jun 30. Chakraborty A, Mandal SM, Mankevich M, Mani RS, Shahabi S, Biswas T, Kodavati M, Sreenivasmurthy SG, Tapryal N, Krishnan B, Hegde ML, Weinfeld M, Ghosh G, Hazra T. PMID: 39574700; PMCID: PMC11580889.
      View in: PubMed   Mentions:
    6. Cooperativity among clustered κB sites within promoters and enhancers dictates transcriptional specificity of NF-κB RelA along with specific cofactors. bioRxiv. 2025 Jun 18. Shahabi S, Biswas T, Shen Y, Sanahmadi R, Zou Y, Ghosh G. PMID: 39411157; PMCID: PMC11475870.
      View in: PubMed   Mentions:
    7. Chromogranin A deficiency attenuates tauopathy by altering epinephrine-alpha-adrenergic receptor signaling in PS19 mice. Nat Commun. 2025 May 20; 16(1):4703. Jati S, Munoz-Mayorga D, Shahabi S, Tang K, Tao Y, Dickson DW, Litvan I, Ghosh G, Mahata SK, Chen X. PMID: 40393970; PMCID: PMC12092710.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    8. RNA control of reverse transcription in a diversity-generating retroelement. Nature. 2025 Feb; 638(8052):1122-1129. Handa S, Biswas T, Chakraborty J, Ghosh G, Paul BG, Ghosh P. PMID: 39779855; PMCID: PMC11995886.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    9. Phosphorylation-induced flexibility of proto-oncogenic Bcl3 regulates transcriptional activation by NF-κB p52 homodimer. bioRxiv. 2024 Oct 23. Pan W, Biswas T, Shahabi S, Suryajaya W, Vasquez A, Du Q, Ghosh G, Wang VY. PMID: 38979190; PMCID: PMC11230411.
      View in: PubMed   Mentions:
    10. Tumor suppressor NME1/NM23-H1 modulates DNA binding of NF-κB RelA. Res Sq. 2024 Oct 14. Shahabi S, Maurya M, Subramaniam S, Ghosh G. PMID: 39483891; PMCID: PMC11527346.
      View in: PubMed   Mentions:
    11. Tumor suppressor NME1/NM23-H1 modulates DNA binding of NF-κB RelA. bioRxiv. 2024 Oct 06. Shahabi S, Maurya M, Subramaniam S, Ghosh G. PMID: 39411158; PMCID: PMC11475868.
      View in: PubMed   Mentions:
    12. Fructose-2,6-bisphosphate restores DNA repair activity of PNKP and ameliorates neurodegenerative symptoms in Huntington's disease. Proc Natl Acad Sci U S A. 2024 Sep 24; 121(39):e2406308121. Chakraborty A, Sreenivasmurthy SG, Miller W, Huai W, Biswas T, Mandal SM, Boscá L, Krishnan B, Ghosh G, Hazra T. PMID: 39298485; PMCID: PMC11441552.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    13. HDX-MS Analysis of Catalytic Activation of IKK2 in the IκB Kinase Complex. Biochemistry. 2024 09 17; 63(18):2323-2334. Suryajaya W, Biswas T, Shahabi S, Mealka M, Huxford T, Ghosh G. PMID: 39185716; PMCID: PMC11731525.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    14. Chromogranin A Deficiency Attenuates Tauopathy by Altering Epinephrine-Alpha-Adrenergic Receptor Signaling. Res Sq. 2024 Aug 09. Mahata S, Jati S, Munoz-Mayorga D, Shahabi S, Tang K, Tao Y, Dickson D, Litvan I, Ghosh G, Chen X. PMID: 39149499; PMCID: PMC11326371.
      View in: PubMed   Mentions:
    15. Fructose-2,6-bisphosphate restores DNA repair activity of PNKP and ameliorates neurodegenerative symptoms in Huntington's disease. bioRxiv. 2024 Jul 16. Chakraborty A, Sreenivasmurthy SG, Miller W, Huai W, Biswas T, Mandal SM, Boscá L, Krishnan B, Ghosh G, Hazra T. PMID: 37961108; PMCID: PMC10634858.
      View in: PubMed   Mentions:
    16. Structural Requirements for Reverse Transcription by a Diversity-generating Retroelement. bioRxiv. 2024 Jun 12. Handa S, Biswas T, Chakraborty J, Ghosh G, Paul BG, Ghosh P. PMID: 37961358; PMCID: PMC10634737.
      View in: PubMed   Mentions:
    17. Chromogranin A (CgA) Deficiency Attenuates Tauopathy by Altering Epinephrine-Alpha-Adrenergic Receptor Signaling. bioRxiv. 2024 Jun 12. Jati S, Munoz-Mayorga D, Shahabi S, Tang K, Tao Y, Dickson DW, Litvan I, Ghosh G, Mahata SK, Chen X. PMID: 38915622; PMCID: PMC11195202.
      View in: PubMed   Mentions:
    18. Transient interactions modulate the affinity of NF-κB transcription factors for DNA. Proc Natl Acad Sci U S A. 2024 Jun 04; 121(23):e2405555121. Li T, Shahabi S, Biswas T, Tsodikov OV, Pan W, Huang DB, Wang VY, Wang Y, Ghosh G. PMID: 38805268; PMCID: PMC11161749.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    19. The DNA glycosylase NEIL2 is protective during SARS-CoV-2 infection. Nat Commun. 2023 12 09; 14(1):8169. Tapryal N, Chakraborty A, Saha K, Islam A, Pan L, Hosoki K, Sayed IM, Duran JM, Alcantara J, Castillo V, Tindle C, Sarker AH, Wakamiya M, Cardenas VJ, Sharma G, Crotty Alexander LE, Sur S, Sahoo D, Ghosh G, Das S, Ghosh P, Boldogh I, Hazra TK. PMID: 38071370; PMCID: PMC10710473.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    20. Structures of NF-κB p52 homodimer-DNA complexes rationalize binding mechanisms and transcription activation. Elife. 2023 02 13; 12. Pan W, Meshcheryakov VA, Li T, Wang Y, Ghosh G, Wang VY. PMID: 36779700; PMCID: PMC9991059.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    21. Analysis of RNA-Protein Interaction Networks Using RNP-MaP. Methods Mol Biol. 2023; 2666:95-105. Saha K, Ghosh G. PMID: 37166659.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    22. Chemical Probing of RNA Structure In Vivo Using SHAPE-MaP and DMS-MaP. Methods Mol Biol. 2023; 2666:81-93. Saha K, Ghosh G. PMID: 37166658.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    23. SHAPE to Probe RNA Structure and RNA-Protein Interactions In Vitro. Methods Mol Biol. 2023; 2666:69-80. Saha K, Ghosh G. PMID: 37166657.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    24. Gut microbial DNA and immune checkpoint gene Vsig4/CRIg are key antagonistic players in healthy aging and age-associated development of hypertension and diabetes. Front Endocrinol (Lausanne). 2022; 13:1037465. Liu MA, Shahabi S, Jati S, Tang K, Gao H, Jin Z, Miller W, Meunier FA, Ying W, van den Bogaart G, Ghosh G, Mahata SK. PMID: 36440192; PMCID: PMC9691654.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    25. Cooperative engagement and subsequent selective displacement of SR proteins define the pre-mRNA 3D structural scaffold for early spliceosome assembly. Nucleic Acids Res. 2022 08 12; 50(14):8262-8278. Saha K, Ghosh G. PMID: 35871302; PMCID: PMC9371905.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    26. Immune Response to COVID-19 in India through Vaccination and Natural Infection. Fortune J Health Sci. 2022; 5(3):432-454. Sarraf TR, Maity S, Ghosh A, Bhattacharjee S, Pani A, Saha K, Chattopadhyay D, Ghosh G, Sen M. PMID: 37304053; PMCID: PMC10257406.
      View in: PubMed   Mentions: 3  
    27. The DNA glycosylase NEIL2 plays a vital role in combating SARS-CoV-2 infection. Res Sq. 2022 May 27. Hazra T, Tapryal N, Chakraborty A, Rayavara K, Wakamiya M, Islam A, Pan L, Hsu J, Tat V, Maruyama J, Hosoki K, Sayed I, Alcantara J, Castillo V, Tindle C, Sarker A, Cardenas V, Sharma G, Alexander LC, Sur S, Ghosh G, Paessler S, Sahoo D, Ghosh P, Das S, Boldogh I, Tseng CT. PMID: 35665009; PMCID: PMC9164514.
      View in: PubMed   Mentions:
    28. Regulatory subunit NEMO promotes polyubiquitin-dependent induction of NF-κB through a targetable second interaction with upstream activator IKK2. J Biol Chem. 2022 05; 298(5):101864. Ko MS, Cohen SN, Polley S, Mahata SK, Biswas T, Huxford T, Ghosh G. PMID: 35339487; PMCID: PMC9035715.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    29. PABP1 Drives the Selective Translation of Influenza A Virus mRNA. J Mol Biol. 2022 03 15; 434(5):167460. de Rozières CM, Pequeno A, Shahabi S, Lucas TM, Godula K, Ghosh G, Joseph S. PMID: 35074482; PMCID: PMC8897273.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    30. Origin of the Functional Distinctiveness of NF-κB/p52. Front Cell Dev Biol. 2021; 9:764164. Ghosh G, Wang VY. PMID: 34888310; PMCID: PMC8650618.
      View in: PubMed   Mentions: 23  
    31. Discovery of a pre-mRNA structural scaffold as a contributor to the mammalian splicing code. Nucleic Acids Res. 2021 07 09; 49(12):7103-7121. Saha K, Fernandez MM, Biswas T, Joseph S, Ghosh G. PMID: 34161584; PMCID: PMC8266590.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    32. Dynamic chromatin association of IκBα is regulated by acetylation and cleavage of histone H4. EMBO Rep. 2021 08 04; 22(8):e52649. Marruecos L, Bertran J, Álvarez-Villanueva D, Mulero MC, Guillén Y, Palma LG, Floor M, Vert A, Arce-Gallego S, Pecharroman I, Batlle L, Villà-Freixa J, Ghosh G, Bigas A, Espinosa L. PMID: 34224210; PMCID: PMC8344903.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    33. Intrapulmonary administration of purified NEIL2 abrogates NF-κB-mediated inflammation. J Biol Chem. 2021 Jan-Jun; 296:100723. Tapryal N, Shahabi S, Chakraborty A, Hosoki K, Wakamiya M, Sarkar G, Sharma G, Cardenas VJ, Boldogh I, Sur S, Ghosh G, Hazra TK. PMID: 33932404; PMCID: PMC8164026.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    34. Immunosuppression of Macrophages Underlies the Cardioprotective Effects of CST (Catestatin). Hypertension. 2021 05 05; 77(5):1670-1682. Ying W, Tang K, Avolio E, Schilling JM, Pasqua T, Liu MA, Cheng H, Gao H, Zhang J, Mahata S, Ko MS, Bandyopadhyay G, Das S, Roth DM, Sahoo D, Webster NJG, Sheikh F, Ghosh G, Patel HH, Ghosh P, van den Bogaart G, Mahata SK. PMID: 33826401; PMCID: PMC8116433.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    35. Structurally plastic NEMO and oligomerization prone IKK2 subunits define the behavior of human IKK2:NEMO complexes in solution. Biochim Biophys Acta Proteins Proteom. 2020 12; 1868(12):140526. Ko MS, Biswas T, Mulero MC, Bobkov AA, Ghosh G, Huxford T. PMID: 32853772; PMCID: PMC7994000.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    36. Structural disruption of exonic stem-loops immediately upstream of the intron regulates mammalian splicing. Nucleic Acids Res. 2020 06 19; 48(11):6294-6309. Saha K, England W, Fernandez MM, Biswas T, Spitale RC, Ghosh G. PMID: 32402057; PMCID: PMC7293017.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    37. Deficiency in classical nonhomologous end-joining-mediated repair of transcribed genes is linked to SCA3 pathogenesis. Proc Natl Acad Sci U S A. 2020 04 07; 117(14):8154-8165. Chakraborty A, Tapryal N, Venkova T, Mitra J, Vasquez V, Sarker AH, Duarte-Silva S, Huai W, Ashizawa T, Ghosh G, Maciel P, Sarkar PS, Hegde ML, Chen X, Hazra TK. PMID: 32205441; PMCID: PMC7148577.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    38. Dissecting the Regulatory Strategies of NF-κB RelA Target Genes in the Inflammatory Response Reveals Differential Transactivation Logics. Cell Rep. 2020 02 25; 30(8):2758-2775.e6. Ngo KA, Kishimoto K, Davis-Turak J, Pimplaskar A, Cheng Z, Spreafico R, Chen EY, Tam A, Ghosh G, Mitchell S, Hoffmann A. PMID: 32101750; PMCID: PMC7061728.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    39. Genome reading by the NF-κB transcription factors. Nucleic Acids Res. 2019 11 04; 47(19):9967-9989. Mulero MC, Wang VY, Huxford T, Ghosh G. PMID: 31501881; PMCID: PMC6821244.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansCells
    40. An NFκB Activity Calculator to Delineate Signaling Crosstalk: Type I and II Interferons Enhance NFκB via Distinct Mechanisms. Front Immunol. 2019; 10:1425. Mitchell S, Mercado EL, Adelaja A, Ho JQ, Cheng QJ, Ghosh G, Hoffmann A. PMID: 31293585; PMCID: PMC6604663.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    41. NF-κB, IκB, and IKK: Integral Components of Immune System Signaling. Adv Exp Med Biol. 2019; 1172:207-226. Mulero MC, Huxford T, Ghosh G. PMID: 31628658.
      View in: PubMed   Mentions: 138     Fields:    Translation:HumansAnimalsCells
    42. A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α. J Vis Exp. 2018 11 02; (141). Polley S, Huang DB, Biswas T, Ghosh G. PMID: 30451218.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    43. Protein Cofactors Are Essential for High-Affinity DNA Binding by the Nuclear Factor κB RelA Subunit. Biochemistry. 2018 05 22; 57(20):2943-2957. Mulero MC, Shahabi S, Ko MS, Schiffer JM, Huang DB, Wang VY, Amaro RE, Huxford T, Ghosh G. PMID: 29708732; PMCID: PMC5993198.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    44. DNA-binding affinity and transcriptional activity of the RelA homodimer of nuclear factor κB are not correlated. J Biol Chem. 2017 11 17; 292(46):18821-18830. Mulero MC, Huang DB, Nguyen HT, Wang VY, Li Y, Biswas T, Ghosh G. PMID: 28935669; PMCID: PMC5704467.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    45. Bcl3 Phosphorylation by Akt, Erk2, and IKK Is Required for Its Transcriptional Activity. Mol Cell. 2017 Aug 03; 67(3):484-497.e5. Wang VY, Li Y, Kim D, Zhong X, Du Q, Ghassemian M, Ghosh G. PMID: 28689659; PMCID: PMC6571149.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    46. Structural Basis for the Activation of IKK1/α. Cell Rep. 2016 11 15; 17(8):1907-1914. Polley S, Passos DO, Huang DB, Mulero MC, Mazumder A, Biswas T, Verma IM, Lyumkis D, Ghosh G. PMID: 27851956; PMCID: PMC5508515.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    47. The NF-κB subunit RelB controls p100 processing by competing with the kinases NIK and IKK1 for binding to p100. Sci Signal. 2016 09 27; 9(447):ra96. Fusco AJ, Mazumder A, Wang VY, Tao Z, Ware C, Ghosh G. PMID: 27678221.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    48. To Swap or Not To Swap. Structure. 2016 09 06; 24(9):1436-8. Ghosh G, Biswas T. PMID: 27602989.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    49. A New DNA Methyltransferase-Histone Deacetylase-Kinase Axis in Innate Immunity. Mol Cell. 2016 08 18; 63(4):544-546. Ghosh G, Sen M. PMID: 27540854.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    50. IκBβ enhances the generation of the low-affinity NFκB/RelA homodimer. Nat Commun. 2015 May 07; 6:7068. Tsui R, Kearns JD, Lynch C, Vu D, Ngo KA, Basak S, Ghosh G, Hoffmann A. PMID: 25946967; PMCID: PMC4425231.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    51. p100/IκBδ sequesters and inhibits NF-κB through kappaBsome formation. Proc Natl Acad Sci U S A. 2014 Nov 11; 111(45):15946-51. Tao Z, Fusco A, Huang DB, Gupta K, Young Kim D, Ware CF, Van Duyne GD, Ghosh G. PMID: 25349408; PMCID: PMC4234596.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    52. N-terminus of the protein kinase CLK1 induces SR protein hyperphosphorylation. Biochem J. 2014 Aug 15; 462(1):143-52. Aubol BE, Plocinik RM, Keshwani MM, McGlone ML, Hagopian JC, Ghosh G, Fu XD, Adams JA. PMID: 24869919; PMCID: PMC5056641.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    53. Probing kinase activation and substrate specificity with an engineered monomeric IKK2. Biochemistry. 2014 Apr 01; 53(12):2064-73. Hauenstein AV, Rogers WE, Shaul JD, Huang DB, Ghosh G, Huxford T. PMID: 24611898; PMCID: PMC3977576.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    54. Analysis of the RelA:CBP/p300 interaction reveals its involvement in NF-κB-driven transcription. PLoS Biol. 2013 Sep; 11(9):e1001647. Mukherjee SP, Behar M, Birnbaum HA, Hoffmann A, Wright PE, Ghosh G. PMID: 24019758; PMCID: PMC3760798.
      View in: PubMed   Mentions: 87     Fields:    Translation:AnimalsCells
    55. PRMT5 dimethylates R30 of the p65 subunit to activate NF-κB. Proc Natl Acad Sci U S A. 2013 Aug 13; 110(33):13516-21. Wei H, Wang B, Miyagi M, She Y, Gopalan B, Huang DB, Ghosh G, Stark GR, Lu T. PMID: 23904475; PMCID: PMC3746871.
      View in: PubMed   Mentions: 141     Fields:    Translation:HumansCells
    56. Role of lysine methylation of NF-κB in differential gene regulation. Proc Natl Acad Sci U S A. 2013 Aug 13; 110(33):13510-5. Lu T, Yang M, Huang DB, Wei H, Ozer GH, Ghosh G, Stark GR. PMID: 23904479; PMCID: PMC3746872.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    57. A structural basis for IκB kinase 2 activation via oligomerization-dependent trans auto-phosphorylation. PLoS Biol. 2013; 11(6):e1001581. Polley S, Huang DB, Hauenstein AV, Fusco AJ, Zhong X, Vu D, Schröfelbauer B, Kim Y, Hoffmann A, Verma IM, Ghosh G, Huxford T. PMID: 23776406; PMCID: PMC3678999.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansCells
    58. A structural basis for selective dimerization by NF-κB RelB. J Mol Biol. 2013 Jun 12; 425(11):1934-1945. Vu D, Huang DB, Vemu A, Ghosh G. PMID: 23485337.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    59. The transcriptional specificity of NF-κB dimers is coded within the κB DNA response elements. Cell Rep. 2012 Oct 25; 2(4):824-39. Wang VY, Huang W, Asagiri M, Spann N, Hoffmann A, Glass C, Ghosh G. PMID: 23063365; PMCID: PMC4167904.
      View in: PubMed   Mentions: 70     Fields:    Translation:AnimalsCells
    60. Understanding NIK regulation from its structure. Structure. 2012 Oct 10; 20(10):1615-7. Tao Z, Ghosh G. PMID: 23063006.
      View in: PubMed   Mentions: 4     Fields:    
    61. NEMO ensures signaling specificity of the pleiotropic IKKβ by directing its kinase activity toward IκBα. Mol Cell. 2012 Jul 13; 47(1):111-21. Schröfelbauer B, Polley S, Behar M, Ghosh G, Hoffmann A. PMID: 22633953; PMCID: PMC3398199.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansAnimalsCells
    62. NF-κB regulation: lessons from structures. Immunol Rev. 2012 Mar; 246(1):36-58. Ghosh G, Wang VY, Huang DB, Fusco A. PMID: 22435546; PMCID: PMC4543363.
      View in: PubMed   Mentions: 106     Fields:    Translation:HumansAnimalsCells
    63. The SRSF1 linker induces semi-conservative ESE binding by cooperating with the RRMs. Nucleic Acids Res. 2011 Nov; 39(21):9413-21. Cho S, Hoang A, Chakrabarti S, Huynh N, Huang DB, Ghosh G. PMID: 21852328; PMCID: PMC3241662.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    64. Interaction between the RNA binding domains of Ser-Arg splicing factor 1 and U1-70K snRNP protein determines early spliceosome assembly. Proc Natl Acad Sci U S A. 2011 May 17; 108(20):8233-8. Cho S, Hoang A, Sinha R, Zhong XY, Fu XD, Krainer AR, Ghosh G. PMID: 21536904; PMCID: PMC3100968.
      View in: PubMed   Mentions: 140     Fields:    Translation:HumansCells
    65. Attenuation of yeast UPR is essential for survival and is mediated by IRE1 kinase. J Cell Biol. 2011 Apr 04; 193(1):41-50. Chawla A, Chakrabarti S, Ghosh G, Niwa M. PMID: 21444691; PMCID: PMC3082189.
      View in: PubMed   Mentions: 63     Fields:    Translation:AnimalsCells
    66. The specificity of innate immune responses is enforced by repression of interferon response elements by NF-κB p50. Sci Signal. 2011 Feb 22; 4(161):ra11. Cheng CS, Feldman KE, Lee J, Verma S, Huang DB, Huynh K, Chang M, Ponomarenko JV, Sun SC, Benedict CA, Ghosh G, Hoffmann A. PMID: 21343618; PMCID: PMC3096068.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    67. NF-κB potentiates caspase independent hydrogen peroxide induced cell death. PLoS One. 2011 Feb 15; 6(2):e16815. Ho JQ, Asagiri M, Hoffmann A, Ghosh G. PMID: 21347231; PMCID: PMC3039651.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    68. Phosphorylation mechanism and structure of serine-arginine protein kinases. FEBS J. 2011 Feb; 278(4):587-97. Ghosh G, Adams JA. PMID: 21205204; PMCID: PMC3079193.
      View in: PubMed   Mentions: 115     Fields:    Translation:HumansAnimalsCells
    69. Understanding the logic of IκB:NF-κB regulation in structural terms. Curr Top Microbiol Immunol. 2011; 349:1-24. Huxford T, Hoffmann A, Ghosh G. PMID: 20845107.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    70. Mechanism of dephosphorylation of the SR protein ASF/SF2 by protein phosphatase 1. J Mol Biol. 2010 Oct 29; 403(3):386-404. Ma CT, Ghosh G, Fu XD, Adams JA. PMID: 20826166; PMCID: PMC2994579.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    71. Flexible regions within I{kappa}B{alpha} create the ubiquitin-independent degradation signal. J Biol Chem. 2010 Oct 22; 285(43):32927-32936. Mathes E, Wang L, Komives E, Ghosh G. PMID: 20682784; PMCID: PMC2963393.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    72. Allosteric interactions direct binding and phosphorylation of ASF/SF2 by SRPK1. Biochemistry. 2009 Dec 08; 48(48):11432-40. Huynh N, Ma CT, Giang N, Hagopian J, Ngo J, Adams J, Ghosh G. PMID: 19886675; PMCID: PMC3322178.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    73. Kinetic enhancement of NF-kappaBxDNA dissociation by IkappaBalpha. Proc Natl Acad Sci U S A. 2009 Nov 17; 106(46):19328-33. Bergqvist S, Alverdi V, Mengel B, Hoffmann A, Ghosh G, Komives EA. PMID: 19887633; PMCID: PMC2780789.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansCells
    74. A structural guide to proteins of the NF-kappaB signaling module. Cold Spring Harb Perspect Biol. 2009 Sep; 1(3):a000075. Huxford T, Ghosh G. PMID: 20066103; PMCID: PMC2773632.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    75. The Nfkb1 and Nfkb2 proteins p105 and p100 function as the core of high-molecular-weight heterogeneous complexes. Mol Cell. 2009 Jun 12; 34(5):591-602. Savinova OV, Hoffmann A, Ghosh G. PMID: 19524538; PMCID: PMC4167889.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansCells
    76. Kinetic control of negative feedback regulators of NF-kappaB/RelA determines their pathogen- and cytokine-receptor signaling specificity. Proc Natl Acad Sci U S A. 2009 Jun 16; 106(24):9619-24. Shih VF, Kearns JD, Basak S, Savinova OV, Ghosh G, Hoffmann A. PMID: 19487661; PMCID: PMC2701028.
      View in: PubMed   Mentions: 81     Fields:    Translation:AnimalsCells
    77. Regiospecific phosphorylation control of the SR protein ASF/SF2 by SRPK1. J Mol Biol. 2009 Jul 24; 390(4):618-34. Ma CT, Hagopian JC, Ghosh G, Fu XD, Adams JA. PMID: 19477182; PMCID: PMC2741142.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    78. Kinase domain insertions define distinct roles of CLK kinases in SR protein phosphorylation. Structure. 2009 Mar 11; 17(3):352-62. Bullock AN, Das S, Debreczeni JE, Rellos P, Fedorov O, Niesen FH, Guo K, Papagrigoriou E, Amos AL, Cho S, Turk BE, Ghosh G, Knapp S. PMID: 19278650; PMCID: PMC2667211.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansCells
    79. Identifying critical non-catalytic residues that modulate protein kinase A activity. PLoS One. 2009; 4(3):e4746. Kennedy EJ, Yang J, Pillus L, Taylor SS, Ghosh G. PMID: 19270744; PMCID: PMC2650257.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    80. Regulation of SR protein phosphorylation and alternative splicing by modulating kinetic interactions of SRPK1 with molecular chaperones. Genes Dev. 2009 Feb 15; 23(4):482-95. Zhong XY, Ding JH, Adams JA, Ghosh G, Fu XD. PMID: 19240134; PMCID: PMC2648651.
      View in: PubMed   Mentions: 115     Fields:    Translation:HumansCells
    81. Contribution of non-catalytic core residues to activity and regulation in protein kinase A. J Biol Chem. 2009 Mar 06; 284(10):6241-8. Yang J, Kennedy EJ, Wu J, Deal MS, Pennypacker J, Ghosh G, Taylor SS. PMID: 19122195; PMCID: PMC2649094.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    82. NF-kappaB p52:RelB heterodimer recognizes two classes of kappaB sites with two distinct modes. EMBO Rep. 2009 Feb; 10(2):152-9. Fusco AJ, Huang DB, Miller D, Wang VY, Vu D, Ghosh G. PMID: 19098713; PMCID: PMC2637311.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    83. Transcriptional outcome of Wnt-Frizzled signal transduction in inflammation: evolving concepts. J Immunol. 2008 Oct 01; 181(7):4441-5. Sen M, Ghosh G. PMID: 18802045.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    84. The IkappaBalpha/NF-kappaB complex has two hot spots, one at either end of the interface. Protein Sci. 2008 Dec; 17(12):2051-8. Bergqvist S, Ghosh G, Komives EA. PMID: 18824506; PMCID: PMC2590914.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    85. Adaptable molecular interactions guide phosphorylation of the SR protein ASF/SF2 by SRPK1. J Mol Biol. 2008 Oct 17; 382(4):894-909. Hagopian JC, Ma CT, Meade BR, Albuquerque CP, Ngo JC, Ghosh G, Jennings PA, Fu XD, Adams JA. PMID: 18687337; PMCID: PMC2741138.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    86. NF-kappaB dictates the degradation pathway of IkappaBalpha. EMBO J. 2008 May 07; 27(9):1357-67. Mathes E, O'Dea EL, Hoffmann A, Ghosh G. PMID: 18401342; PMCID: PMC2374849.
      View in: PubMed   Mentions: 116     Fields:    Translation:HumansAnimalsCells
    87. A sliding docking interaction is essential for sequential and processive phosphorylation of an SR protein by SRPK1. Mol Cell. 2008 Mar 14; 29(5):563-76. Ngo JC, Giang K, Chakrabarti S, Ma CT, Huynh N, Hagopian JC, Dorrestein PC, Fu XD, Adams JA, Ghosh G. PMID: 18342604; PMCID: PMC2852395.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimalsCells
    88. Stabilization of RelB requires multidomain interactions with p100/p52. J Biol Chem. 2008 May 02; 283(18):12324-32. Fusco AJ, Savinova OV, Talwar R, Kearns JD, Hoffmann A, Ghosh G. PMID: 18321863; PMCID: PMC2431000.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    89. Pre-folding IkappaBalpha alters control of NF-kappaB signaling. J Mol Biol. 2008 Jun 27; 380(1):67-82. Truhlar SM, Mathes E, Cervantes CF, Ghosh G, Komives EA. PMID: 18511071; PMCID: PMC2519148.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    90. Identification of functionally distinct regions that mediate biological activity of the protein kinase a homolog Tpk2. J Biol Chem. 2008 Jan 11; 283(2):1084-93. Kennedy EJ, Ghosh G, Pillus L. PMID: 17971450.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    91. Inhibitor kappaB kinase beta binding by inhibitor kappaB kinase gamma. Biochemistry. 2007 Oct 30; 46(43):12482-90. Drew D, Shimada E, Huynh K, Bergqvist S, Talwar R, Karin M, Ghosh G. PMID: 17924664.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    92. Deletion of the N-terminus of SF2/ASF permits RS-domain-independent pre-mRNA splicing. PLoS One. 2007 Sep 05; 2(9):e854. Shaw SD, Chakrabarti S, Ghosh G, Krainer AR. PMID: 17786225; PMCID: PMC1952110.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    93. X-ray structure of a NF-kappaB p50/RelB/DNA complex reveals assembly of multiple dimers on tandem kappaB sites. J Mol Biol. 2007 Oct 26; 373(3):723-34. Moorthy AK, Huang DB, Wang VY, Vu D, Ghosh G. PMID: 17869269; PMCID: PMC4167888.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    94. Ordered multi-site phosphorylation of the splicing factor ASF/SF2 by SRPK1. J Mol Biol. 2008 Feb 08; 376(1):55-68. Ma CT, Velazquez-Dones A, Hagopian JC, Ghosh G, Fu XD, Adams JA. PMID: 18155240.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansCells
    95. Structurally unique yeast and mammalian serine-arginine protein kinases catalyze evolutionarily conserved phosphorylation reactions. J Biol Chem. 2007 Aug 10; 282(32):23036-43. Lukasiewicz R, Velazquez-Dones A, Huynh N, Hagopian J, Fu XD, Adams J, Ghosh G. PMID: 17517895.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    96. A fourth IkappaB protein within the NF-kappaB signaling module. Cell. 2007 Jan 26; 128(2):369-81. Basak S, Kim H, Kearns JD, Tergaonkar V, O'Dea E, Werner SL, Benedict CA, Ware CF, Ghosh G, Verma IM, Hoffmann A. PMID: 17254973; PMCID: PMC1831796.
      View in: PubMed   Mentions: 211     Fields:    Translation:AnimalsCells
    97. SR protein kinase 1 is resilient to inactivation. Structure. 2007 Jan; 15(1):123-33. Ngo JC, Gullingsrud J, Giang K, Yeh MJ, Fu XD, Adams JA, McCammon JA, Ghosh G. PMID: 17223538.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    98. The RGG domain of Npl3p recruits Sky1p through docking interactions. J Mol Biol. 2007 Mar 16; 367(1):249-61. Lukasiewicz R, Nolen B, Adams JA, Ghosh G. PMID: 17239901.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    99. Thermodynamics reveal that helix four in the NLS of NF-kappaB p65 anchors IkappaBalpha, forming a very stable complex. J Mol Biol. 2006 Jul 07; 360(2):421-34. Bergqvist S, Croy CH, Kjaergaard M, Huxford T, Ghosh G, Komives EA. PMID: 16756995; PMCID: PMC2680085.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    100. The 20S proteasome processes NF-kappaB1 p105 into p50 in a translation-independent manner. EMBO J. 2006 May 03; 25(9):1945-56. Moorthy AK, Savinova OV, Ho JQ, Wang VY, Vu D, Ghosh G. PMID: 16619030; PMCID: PMC1456938.
      View in: PubMed   Mentions: 69     Fields:    Translation:AnimalsCells
    101. Inhibition of transcription factor NF-kappaB activation by kappaB-Ras. Methods Enzymol. 2006; 407:527-34. Huxford T, Ghosh G. PMID: 16757350.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    102. Regulated cellular partitioning of SR protein-specific kinases in mammalian cells. Mol Biol Cell. 2006 Feb; 17(2):876-85. Ding JH, Zhong XY, Hagopian JC, Cruz MM, Ghosh G, Feramisco J, Adams JA, Fu XD. PMID: 16319169; PMCID: PMC1356596.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimalsCells
    103. Pho5p and newly identified nucleotide pyrophosphatases/ phosphodiesterases regulate extracellular nucleotide phosphate metabolism in Saccharomyces cerevisiae. Eukaryot Cell. 2005 Nov; 4(11):1892-901. Kennedy EJ, Pillus L, Ghosh G. PMID: 16278456; PMCID: PMC1287867.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    104. Mass spectrometric and kinetic analysis of ASF/SF2 phosphorylation by SRPK1 and Clk/Sty. J Biol Chem. 2005 Dec 16; 280(50):41761-8. Velazquez-Dones A, Hagopian JC, Ma CT, Zhong XY, Zhou H, Ghosh G, Fu XD, Adams JA. PMID: 16223727.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansCells
    105. Interplay between SRPK and Clk/Sty kinases in phosphorylation of the splicing factor ASF/SF2 is regulated by a docking motif in ASF/SF2. Mol Cell. 2005 Oct 07; 20(1):77-89. Ngo JC, Chakrabarti S, Ding JH, Velazquez-Dones A, Nolen B, Aubol BE, Adams JA, Fu XD, Ghosh G. PMID: 16209947.
      View in: PubMed   Mentions: 125     Fields:    Translation:HumansAnimalsCells
    106. PKR and eIF2alpha: integration of kinase dimerization, activation, and substrate docking. Cell. 2005 Sep 23; 122(6):823-5. Taylor SS, Haste NM, Ghosh G. PMID: 16179248.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansAnimalsCells
    107. A c-Rel subdomain responsible for enhanced DNA-binding affinity and selective gene activation. Genes Dev. 2005 Sep 15; 19(18):2138-51. Sanjabi S, Williams KJ, Saccani S, Zhou L, Hoffmann A, Ghosh G, Gerondakis S, Natoli G, Smale ST. PMID: 16166378; PMCID: PMC1221885.
      View in: PubMed   Mentions: 74     Fields:    Translation:AnimalsCells
    108. NF-kappaB RelB forms an intertwined homodimer. Structure. 2005 Sep; 13(9):1365-73. Huang DB, Vu D, Ghosh G. PMID: 16154093.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    109. Enhanced intracellular mobility and nuclear accumulation of DNA plasmids associated with a karyophilic protein. Hum Gene Ther. 2005 Feb; 16(2):200-8. Mesika A, Kiss V, Brumfeld V, Ghosh G, Reich Z. PMID: 15761260.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    110. Crystal structure of a free kappaB DNA: insights into DNA recognition by transcription factor NF-kappaB. J Mol Biol. 2005 Feb 11; 346(1):147-60. Huang DB, Phelps CB, Fusco AJ, Ghosh G. PMID: 15663934.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    111. Activation of IKKalpha target genes depends on recognition of specific kappaB binding sites by RelB:p52 dimers. EMBO J. 2004 Oct 27; 23(21):4202-10. Bonizzi G, Bebien M, Otero DC, Johnson-Vroom KE, Cao Y, Vu D, Jegga AG, Aronow BJ, Ghosh G, Rickert RC, Karin M. PMID: 15470505; PMCID: PMC524385.
      View in: PubMed   Mentions: 155     Fields:    Translation:AnimalsCells
    112. Regulation of protein kinases; controlling activity through activation segment conformation. Mol Cell. 2004 Sep 10; 15(5):661-75. Nolen B, Taylor S, Ghosh G. PMID: 15350212.
      View in: PubMed   Mentions: 550     Fields:    Translation:HumansAnimalsCells
    113. Biophysical characterization of the free IkappaBalpha ankyrin repeat domain in solution. Protein Sci. 2004 Jul; 13(7):1767-77. Croy CH, Bergqvist S, Huxford T, Ghosh G, Komives EA. PMID: 15215520; PMCID: PMC2279933.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansAnimalsCells
    114. Chemical clamping allows for efficient phosphorylation of the RNA carrier protein Npl3. J Biol Chem. 2004 Jul 16; 279(29):30182-8. Aubol BE, Ungs L, Lukasiewicz R, Ghosh G, Adams JA. PMID: 15145958.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    115. Inhibition of NF-kappaB activity by IkappaBbeta in association with kappaB-Ras. Mol Cell Biol. 2004 Apr; 24(7):3048-56. Chen Y, Vallee S, Wu J, Vu D, Sondek J, Ghosh G. PMID: 15024091; PMCID: PMC371134.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    116. Discreet mutations from c-Rel to v-Rel alter kappaB DNA recognition, IkappaBalpha binding, and dimerization: implications for v-Rel oncogenicity. Oncogene. 2004 Feb 12; 23(6):1229-38. Phelps CB, Ghosh G. PMID: 14961076.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    117. Molecular mimicry of the NF-kappaB DNA target site by a selected RNA aptamer. Curr Opin Struct Biol. 2004 Feb; 14(1):21-7. Ghosh G, Huang DB, Huxford T. PMID: 15102445.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    118. Novel destabilization of nucleotide binding by the gamma phosphate of ATP in the yeast SR protein kinase Sky1p. Biochemistry. 2003 Nov 11; 42(44):12813-20. Aubol BE, Nolen B, Shaffer J, Ghosh G, Adams JA. PMID: 14596595.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    119. Processive phosphorylation of alternative splicing factor/splicing factor 2. Proc Natl Acad Sci U S A. 2003 Oct 28; 100(22):12601-6. Aubol BE, Chakrabarti S, Ngo J, Shaffer J, Nolen B, Fu XD, Ghosh G, Adams JA. PMID: 14555757; PMCID: PMC240664.
      View in: PubMed   Mentions: 66     Fields:    Translation:Cells
    120. Nucleotide-induced conformational changes in the Saccharomyces cerevisiae SR protein kinase, Sky1p, revealed by X-ray crystallography. Biochemistry. 2003 Aug 19; 42(32):9575-85. Nolen B, Ngo J, Chakrabarti S, Vu D, Adams JA, Ghosh G. PMID: 12911299.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    121. Crystal structure of NF-kappaB (p50)2 complexed to a high-affinity RNA aptamer. Proc Natl Acad Sci U S A. 2003 Aug 05; 100(16):9268-73. Huang DB, Vu D, Cassiday LA, Zimmerman JM, Maher LJ, Ghosh G. PMID: 12886018; PMCID: PMC170907.
      View in: PubMed   Mentions: 81     Fields:    Translation:AnimalsCells
    122. X-ray crystal structure of an IkappaBbeta x NF-kappaB p65 homodimer complex. J Biol Chem. 2003 Jun 20; 278(25):23094-100. Malek S, Huang DB, Huxford T, Ghosh S, Ghosh G. PMID: 12686541.
      View in: PubMed   Mentions: 54     Fields:    Translation:Cells
    123. KappaB-Ras binds to the unique insert within the ankyrin repeat domain of IkappaBbeta and regulates cytoplasmic retention of IkappaBbeta x NF-kappaB complexes. J Biol Chem. 2003 Jun 20; 278(25):23101-6. Chen Y, Wu J, Ghosh G. PMID: 12672800.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    124. Solvent exposed non-contacting amino acids play a critical role in NF-kappaB/IkappaBalpha complex formation. J Mol Biol. 2002 Dec 06; 324(4):587-97. Huxford T, Mishler D, Phelps CB, Huang DB, Sengchanthalangsy LL, Reeves R, Hughes CA, Komives EA, Ghosh G. PMID: 12460563.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    125. p105.Ikappa Bgamma and prototypical Ikappa Bs use a similar mechanism to bind but a different mechanism to regulate the subcellular localization of NF-kappa B. J Biol Chem. 2003 Jan 03; 278(1):556-66. Moorthy AK, Ghosh G. PMID: 12399470.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    126. Mechanistic insights into Sky1p, a yeast homologue of the mammalian SR protein kinases. Biochemistry. 2002 Aug 06; 41(31):10002-9. Aubol BE, Nolen B, Vu D, Ghosh G, Adams JA. PMID: 12146964.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    127. The kappa B DNA sequence from the HIV long terminal repeat functions as an allosteric regulator of HIV transcription. J Biol Chem. 2002 Jul 05; 277(27):24701-8. Chen-Park FE, Huang DB, Noro B, Thanos D, Ghosh G. PMID: 11970949.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    128. The x-ray crystal structure of the NF-kappa B p50.p65 heterodimer bound to the interferon beta -kappa B site. J Biol Chem. 2002 Jul 05; 277(27):24694-700. Berkowitz B, Huang DB, Chen-Park FE, Sigler PB, Ghosh G. PMID: 11970948.
      View in: PubMed   Mentions: 40     Fields:    Translation:Cells
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