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Amy Jak

Title(s)Associate Professor In Residence, Psychiatry
SchoolHealth Sciences
Address9500 Gilman Drive #9116B
La Jolla CA 92093
Phone858-642-3742
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    Biography

    Dr. Jak received her doctorate in Clinical Psychology, with specialization in neuropsychology, from the University of Cincinnati (2004). She completed a postdoctoral fellowship in neuropsychology at the VA San Diego Healthcare System/Veteran’s Medical Research Foundation from 2004-2007. Currently, she is an Assistant Professor (In Residence) of Psychiatry at UCSD and a Staff Neurosychologist and Director, TBI Cognitive Rehabilitation Clinic, at the Veterans Affairs San Diego Healthcare System. Dr. Jak’s research interests are in novel treatments for mild TBI as well as in cognitive aging and mild cognitive impairment.

    Research Interests

    Dr. Jak’s research focuses on neuropsychology and neuroimaging in normal aging and mild cognitive impairment. Specifically, her current research examines how protective behavioral factors (e.g., physically and mentally active lifestyles) impact cognition and brain structural integrity. Additionally, her research examines the potential for activity levels to modify genetic risk for cognitive decline. Other research interests center on the neuropsychological presentation of mild cognitive impairment, mild traumatic brain injury, and post-traumatic stress disorder.

    Clinical Focus

    Dr. Jak is the Director of Traumatic Brain Injury Cognitive Rehabilitation at the VA San Diego Healthcare system and provides psychoeducation and training in compensatory strategies to veterans with mild to moderate TBI. She is also a Clinical Neuropsychologist within the Department's private practice plan (UCSD Neuropsychological Associates). She conducts clinical neuropsychological evaluations of adults with a wide range of neurologic and psychiatric disorders, with particular emphasis on dementia and traumatic brain injury.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Aspects of Executive Dysfunction and Racial/Ethnic Minority Status are Associated with Unemployment Duration in Veterans with a History of Mild-to-Moderate Traumatic Brain Injury. Arch Phys Med Rehabil. 2020 May 13. Clark JMR, Seewald PM, Wu K, Jak AJ, Twamley EW. PMID: 32416150.
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    2. Factors associated with employment and work perception in combat-exposed veterans. Rehabil Psychol. 2020 Apr 16. Merritt VC, Jurick SM, Crocker LD, Keller AV, Hoffman SN, Jak AJ. PMID: 32297778.
      View in: PubMed   Mentions:    Fields:    
    3. Extensive memory testing improves prediction of progression to MCI in late middle age. Alzheimers Dement (Amst). 2020; 12(1):e12004. Gustavson DE, Elman JA, Sanderson-Cimino M, Franz CE, Panizzon MS, Jak AJ, Reynolds CA, Neale MC, Lyons MJ, Kremen WS. PMID: 32284960.
      View in: PubMed   Mentions:
    4. PTSD, but not history of mTBI, is associated with altered myelin in combat-exposed Iraq and Afghanistan Veterans. Clin Neuropsychol. 2020 Mar 16; 1-18. Jak AJ, Jurick S, Hoffman S, Evangelista ND, Deford N, Keller A, Merritt VC, Sanderson-Cimino M, Sorg S, Delano-Wood L, Bangen KJ. PMID: 32176590.
      View in: PubMed   Mentions:    Fields:    
    5. Associations Between Multiple Remote Mild TBIs and Objective Neuropsychological Functioning and Subjective Symptoms in Combat-Exposed Veterans. Arch Clin Neuropsychol. 2020 Mar 02. Merritt VC, Jurick SM, Crocker LD, Sullan MJ, Sakamoto MS, Davey DK, Hoffman SN, Keller AV, Jak AJ. PMID: 32128559.
      View in: PubMed   Mentions:    Fields:    
    6. Cognition and functional capacity following traumatic brain injury in veterans. Rehabil Psychol. 2020 Feb; 65(1):72-79. Clark JMR, Jak AJ, Twamley EW. PMID: 31670546.
      View in: PubMed   Mentions:    Fields:    
    7. Psychological Symptoms and Rates of Performance Validity Improve Following Trauma-Focused Treatment in Veterans with PTSD and History of Mild-to-Moderate TBI. J Int Neuropsychol Soc. 2020 Jan; 26(1):108-118. Jurick SM, Crocker LD, Merritt VC, Hoffman SN, Keller AV, Eglit GML, Thomas KR, Norman SB, Schiehser DM, Rodgers CS, Twamley EW, Jak AJ. PMID: 31658923.
      View in: PubMed   Mentions:    Fields:    
    8. MCI-to-normal reversion using neuropsychological criteria in the Alzheimer's Disease Neuroimaging Initiative. Alzheimers Dement. 2019 10; 15(10):1322-1332. Thomas KR, Edmonds EC, Eppig JS, Wong CG, Weigand AJ, Bangen KJ, Jak AJ, Delano-Wood L, Galasko DR, Salmon DP, Edland SD, Bondi MW. PMID: 31495605.
      View in: PubMed   Mentions:    Fields:    
    9. Utility of the D-KEFS Color Word Interference Test as an embedded measure of performance validity. Clin Neuropsychol. 2020 Feb; 34(2):332-352. Eglit GML, Jurick SM, Delis DC, Filoteo JV, Bondi MW, Jak AJ. PMID: 31352854.
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    10. APOE-e4 Genotype is Associated with Elevated Post-Concussion Symptoms in Military Veterans with a Remote History of Mild Traumatic Brain Injury. Arch Clin Neuropsychol. 2019 Jul 26; 34(5):706-712. Merritt VC, Lapira KM, Clark AL, Sorg SF, Werhane ML, Jak AJ, Bondi MW, Schiehser DM, Delano-Wood L. PMID: 30521018.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. The Role of Pain Catastrophizing in Cognitive Functioning Among Veterans With a History of Mild Traumatic Brain Injury. J Head Trauma Rehabil. 2019 Jul/Aug; 34(4):E61-E66. Hoffman SN, Herbert MS, Crocker LD, DeFord NE, Keller AV, Jurick SM, Sanderson-Cimino M, Jak AJ. PMID: 30499934.
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    12. Mild traumatic brain injury characteristics do not negatively influence cognitive processing therapy attendance or outcomes. J Psychiatr Res. 2019 09; 116:7-13. Crocker LD, Jurick SM, Thomas KR, Keller AV, Sanderson-Cimino M, Hoffman SN, Boyd B, Rodgers C, Norman SB, Lang AJ, Twamley EW, Jak AJ. PMID: 31174014.
      View in: PubMed   Mentions:    Fields:    
    13. Evaluation of objective and subjective clinical outcomes in combat veterans with and without mild TBI and PTSD: A four-group design. J Clin Exp Neuropsychol. 2019 09; 41(7):665-679. Merritt VC, Jurick SM, Crocker LD, Hoffman SN, Keller AV, DeFord N, Jak AJ. PMID: 31084252.
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    14. Artificially low mild cognitive impairment to normal reversion rate in the Alzheimer's Disease Neuroimaging Initiative. Alzheimers Dement. 2019 04; 15(4):561-569. Thomas KR, Eppig JS, Weigand AJ, Edmonds EC, Wong CG, Jak AJ, Delano-Wood L, Galasko DR, Salmon DP, Edland SD, Bondi MW. PMID: 30610833.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. A systematic review of sex differences in concussion outcome: What do we know? Clin Neuropsychol. 2019 08; 33(6):1016-1043. Merritt VC, Padgett CR, Jak AJ. PMID: 30618335.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. Predictors of work outcomes following supported employment in veterans with a history of traumatic brain injury. NeuroRehabilitation. 2019; 44(3):333-339. Church HR, Seewald PM, Clark JMR, Jak AJ, Twamley EW. PMID: 31177239.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. SMART-CPT for veterans with comorbid post-traumatic stress disorder and history of traumatic brain injury: a randomised controlled trial. J Neurol Neurosurg Psychiatry. 2019 03; 90(3):333-341. Jak AJ, Jurick S, Crocker LD, Sanderson-Cimino M, Aupperle R, Rodgers CS, Thomas KR, Boyd B, Norman SB, Lang AJ, Keller AV, Schiehser DM, Twamley EW. PMID: 30554135.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    18. Neurocognition, psychiatric symptoms, and lifetime homelessness among veterans with a history of traumatic brain injury. Psychiatry Res. 2019 01; 271:167-170. Twamley EW, Hays CC, Van Patten R, Seewald PM, Orff HJ, Depp CA, Olsen DC, Jak AJ. PMID: 30481694.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. Mild Traumatic Brain Injury Burden Moderates the Relationship Between Cognitive Functioning and Suicidality in Iraq/Afghanistan-Era Veterans. J Int Neuropsychol Soc. 2019 01; 25(1):79-89. Crocker LD, Keller AV, Jurick SM, Bomyea J, Hays CC, Twamley EW, Jak AJ. PMID: 30444208.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    20. Neuropsychological Criteria for Mild Cognitive Impairment in the Framingham Heart Study's Old-Old. Dement Geriatr Cogn Disord. 2018; 46(5-6):253-265. Wong CG, Thomas KR, Edmonds EC, Weigand AJ, Bangen KJ, Eppig JS, Jak AJ, Devine SA, Delano-Wood L, Libon DJ, Edland SD, Au R, Bondi MW. PMID: 30391953.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    21. Neurobehavioral symptom validity and performance validity in veterans: Evidence for distinct outcomes across data types. Appl Neuropsychol Adult. 2020 Jan-Feb; 27(1):62-72. Bomyea J, Jurick SM, Keller AV, Hays CC, Twamley EW, Jak AJ. PMID: 30183368.
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    22. Worse baseline executive functioning is associated with dropout and poorer response to trauma-focused treatment for veterans with PTSD and comorbid traumatic brain injury. Behav Res Ther. 2018 09; 108:68-77. Crocker LD, Jurick SM, Thomas KR, Keller AV, Sanderson-Cimino M, Boyd B, Rodgers C, Twamley EW, Jak AJ. PMID: 30031369.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    23. Underdiagnosis of mild cognitive impairment: A consequence of ignoring practice effects. Alzheimers Dement (Amst). 2018; 10:372-381. Elman JA, Jak AJ, Panizzon MS, Tu XM, Chen T, Reynolds CA, Gustavson DE, Franz CE, Hatton SN, Jacobson KC, Toomey R, McKenzie R, Xian H, Lyons MJ, Kremen WS. PMID: 30003138.
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    24. The Minnesota Multiphasic Personality Inventory-2-RF in Treatment-Seeking Veterans with History of Mild Traumatic Brain Injury. Arch Clin Neuropsychol. 2018 May 01; 34(3):366-380. Jurick SM, Crocker LD, Keller AV, Hoffman SN, Bomyea J, Jacobson MW, Jak AJ. PMID: 29850866.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    25. Contributions to Executive Dysfunction in Operation Enduring Freedom/Operation Iraqi Freedom Veterans With Posttraumatic Stress Disorder and History of Mild Traumatic Brain Injury. J Head Trauma Rehabil. 2018 Mar/Apr; 33(2):E41-E52. Jurick SM, Crocker LD, Sanderson-Cimino M, Keller AV, Trenova LS, Boyd BL, Twamley EW, Rodgers CS, Schiehser DM, Aupperle RL, Jak AJ. PMID: 28520663.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    26. Faulty Adaptation to Repeated Face-Name Associative Pairs in Mild Cognitive Impairment is Predictive of Cognitive Decline. Arch Clin Neuropsychol. 2018 Mar 01; 33(2):168-183. Jurick SM, Weissberger GH, Clark LR, Wierenga CE, Chang YL, Schiehser DM, Han SD, Jak AJ, Dev SI, Bondi MW. PMID: 28655152.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    27. Correlates of employment and postsecondary education enrolment in Afghanistan and Iraq veterans with traumatic brain injuries. Brain Inj. 2018; 32(5):544-549. Olsen DC, Hays CC, Orff HJ, Jak AJ, Twamley EW. PMID: 29370539.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    28. Assessing Working Memory in Mild Cognitive Impairment with Serial Order Recall. J Alzheimers Dis. 2018; 61(3):917-928. Emrani S, Libon DJ, Lamar M, Price CC, Jefferson AL, Gifford KA, Hohman TJ, Nation DA, Delano-Wood L, Jak A, Bangen KJ, Bondi MW, Brickman AM, Manly J, Swenson R, Au R. PMID: 29254087.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    29. Pilot investigation of a novel white matter imaging technique in Veterans with and without history of mild traumatic brain injury. Brain Inj. 2018; 32(10):1256-1265. Jurick SM, Hoffman SN, Sorg S, Keller AV, Evangelista ND, DeFord NE, Sanderson-Cimino M, Bangen KJ, Delano-Wood L, Deoni S, Jak AJ. PMID: 30169992.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    30. Neurocognition in PTSD: Treatment Insights and Implications. Curr Top Behav Neurosci. 2018; 38:93-116. Jak AJ, Crocker LD, Aupperle RL, Clausen A, Bomyea J. PMID: 28025811.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    31. Pupillary Responses as a Biomarker of Early Risk for Alzheimer's Disease. J Alzheimers Dis. 2017; 56(4):1419-1428. Granholm EL, Panizzon MS, Elman JA, Jak AJ, Hauger RL, Bondi MW, Lyons MJ, Franz CE, Kremen WS. PMID: 28157098.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    32. Compensatory Cognitive Training for Operation Enduring Freedom/Operation Iraqi Freedom/Operation New Dawn Veterans With Mild Traumatic Brain Injury. J Head Trauma Rehabil. 2017 Jan/Feb; 32(1):16-24. Storzbach D, Twamley EW, Roost MS, Golshan S, Williams RM, O'Neil M, Jak AJ, Turner AP, Kowalski HM, Pagulayan KF, Huckans M. PMID: 27022961.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    33. White Matter Associations With Performance Validity Testing in Veterans With Mild Traumatic Brain Injury: The Utility of Biomarkers in Complicated Assessment. J Head Trauma Rehabil. 2016 Sep-Oct; 31(5):346-59. Clark AL, Sorg SF, Schiehser DM, Bigler ED, Bondi MW, Jacobson MW, Jak AJ, Delano-Wood L. PMID: 26360002.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    34. Predictors of cognitive and physical fatigue in post-acute mild-moderate traumatic brain injury. Neuropsychol Rehabil. 2017 Oct; 27(7):1031-1046. Schiehser DM, Delano-Wood L, Jak AJ, Hanson KL, Sorg SF, Orff H, Clark AL. PMID: 27535726.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    35. Problem alcohol use in veterans with mild traumatic brain injury: Associations with cognitive performance and psychiatric symptoms. J Clin Exp Neuropsychol. 2016 12; 38(10):1115-30. Hanson KL, Schiehser DM, Clark AL, Sorg SF, Kim RT, Jacobson MW, Werhane ML, Jak AJ, Twamley EW, Delano-Wood L. PMID: 27430280.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    36. Neuropsychological Criteria for Mild Cognitive Impairment and Dementia Risk in the Framingham Heart Study. J Int Neuropsychol Soc. 2016 10; 22(9):937-943. Jak AJ, Preis SR, Beiser AS, Seshadri S, Wolf PA, Bondi MW, Au R. PMID: 27029348.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    37. "Missed" Mild Cognitive Impairment: High False-Negative Error Rate Based on Conventional Diagnostic Criteria. J Alzheimers Dis. 2016 03 31; 52(2):685-91. Edmonds EC, Delano-Wood L, Jak AJ, Galasko DR, Salmon DP, Bondi MW. PMID: 27031477.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    38. Neuropsychiatric Predictors of Post-Injury Headache After Mild-Moderate Traumatic Brain Injury in Veterans. Headache. 2016 Apr; 56(4):699-710. Bomyea J, Lang AJ, Delano-Wood L, Jak A, Hanson KL, Sorg S, Clark AL, Schiehser DM. PMID: 27028095.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    39. Is bigger always better? The importance of cortical configuration with respect to cognitive ability. Neuroimage. 2016 Apr 01; 129:356-366. Vuoksimaa E, Panizzon MS, Chen CH, Fiecas M, Eyler LT, Fennema-Notestine C, Hagler DJ, Franz CE, Jak AJ, Lyons MJ, Neale MC, Rinker DA, Thompson WK, Tsuang MT, Dale AM, Kremen WS. PMID: 26827810.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    40. Advanced neuroimaging to quantify myelin in vivo: Application to mild TBI. Brain Inj. 2016; 30(12):1452-1457. Jurick SM, Bangen KJ, Evangelista ND, Sanderson-Cimino M, Delano-Wood L, Jak AJ. PMID: 27834545.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    41. Postconcussive symptom overreporting in Iraq/Afghanistan Veterans with mild traumatic brain injury. J Rehabil Res Dev. 2016; 53(5):571-584. Jurick SM, Twamley EW, Crocker LD, Hays CC, Orff HJ, Golshan S, Jak AJ. PMID: 27898153.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    42. Repetitive Transcranial Magnetic Stimulation in Managing Mild Traumatic Brain Injury-Related Headaches. Neuromodulation. 2016 Feb; 19(2):133-41. Leung A, Shukla S, Fallah A, Song D, Lin L, Golshan S, Tsai A, Jak A, Polston G, Lee R. PMID: 26555886.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    43. CogSMART Compensatory Cognitive Training for Traumatic Brain Injury: Effects Over 1 Year. J Head Trauma Rehabil. 2015 Nov-Dec; 30(6):391-401. Twamley EW, Thomas KR, Gregory AM, Jak AJ, Bondi MW, Delis DC, Lohr JB. PMID: 25033034.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    44. Evaluation of a hybrid treatment for Veterans with comorbid traumatic brain injury and posttraumatic stress disorder: Study protocol for a randomized controlled trial. Contemp Clin Trials. 2015 Nov; 45(Pt B):210-216. Jak AJ, Aupperle R, Rodgers CS, Lang AJ, Schiehser DM, Norman SB, Twamley EW. PMID: 26500169.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    45. Visuoconstructional Impairment in Subtypes of Mild Cognitive Impairment. Appl Neuropsychol Adult. 2016; 23(1):43-52. Ahmed S, Brennan L, Eppig J, Price CC, Lamar M, Delano-Wood L, Bangen KJ, Edmonds EC, Clark L, Nation DA, Jak A, Au R, Swenson R, Bondi MW, Libon DJ. PMID: 26397732.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    46. Psychiatric comorbidity effects on compensatory cognitive training outcomes for veterans with traumatic brain injuries. Rehabil Psychol. 2015 Aug; 60(3):303-8. Walter KH, Jak AJ, Twamley EW. PMID: 26147236.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    47. The Relationship Between Postconcussive Symptoms and Quality of Life in Veterans With Mild to Moderate Traumatic Brain Injury. J Head Trauma Rehabil. 2015 Jul-Aug; 30(4):E21-8. Schiehser DM, Twamley EW, Liu L, Matevosyan A, Filoteo JV, Jak AJ, Orff HJ, Hanson KL, Sorg SF, Delano-Wood L. PMID: 24922041.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    48. Neuropsychological performance in treatment-seeking Operation Enduring Freedom/Operation Iraqi Freedom Veterans with a history of mild traumatic brain injury. J Clin Exp Neuropsychol. 2015; 37(4):379-88. Jak AJ, Gregory A, Orff HJ, Colón C, Steele N, Schiehser DM, Delano-Wood L, Jurick SM, Twamley EW. PMID: 25850338.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    49. Validation of the Modified Fatigue Impact Scale in mild to moderate traumatic brain injury. J Head Trauma Rehabil. 2015 Mar-Apr; 30(2):116-21. Schiehser DM, Delano-Wood L, Jak AJ, Matthews SC, Simmons AN, Jacobson MW, Filoteo JV, Bondi MW, Orff HJ, Liu L. PMID: 24413076.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    50. Does degree of gyrification underlie the phenotypic and genetic associations between cortical surface area and cognitive ability? Neuroimage. 2015 Feb 01; 106:154-60. Docherty AR, Hagler DJ, Panizzon MS, Neale MC, Eyler LT, Fennema-Notestine C, Franz CE, Jak A, Lyons MJ, Rinker DA, Thompson WK, Tsuang MT, Dale AM, Kremen WS. PMID: 25433211.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    51. Hippocampal atrophy varies by neuropsychologically defined MCI among men in their 50s. Am J Geriatr Psychiatry. 2015 May; 23(5):456-65. Jak AJ, Panizzon MS, Spoon KM, Fennema-Notestine C, Franz CE, Thompson WK, Jacobson KC, Xian H, Eyler LT, Vuoksimaa E, Toomey R, Lyons MJ, Neale MC, Tsuang MT, Dale AM, Kremen WS. PMID: 25306196.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    52. Susceptibility of the conventional criteria for mild cognitive impairment to false-positive diagnostic errors. Alzheimers Dement. 2015 Apr; 11(4):415-24. Edmonds EC, Delano-Wood L, Clark LR, Jak AJ, Nation DA, McDonald CR, Libon DJ, Au R, Galasko D, Salmon DP, Bondi MW. PMID: 24857234.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    53. Authors' response to: commentary by Johnson et al. Int J Epidemiol. 2014 Apr; 43(2):612-3. Kremen WS, Jak AJ, Panizzon MS, Spoon KM, Franz CE, Thompson WK, Jacobson KC, Vasilopoulos T, Vuoksimaa E, Xian H, Toomey R, Lyons MJ. PMID: 24760875.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    54. The Genetic Association Between Neocortical Volume and General Cognitive Ability Is Driven by Global Surface Area Rather Than Thickness. Cereb Cortex. 2015 Aug; 25(8):2127-37. Vuoksimaa E, Panizzon MS, Chen CH, Fiecas M, Eyler LT, Fennema-Notestine C, Hagler DJ, Fischl B, Franz CE, Jak A, Lyons MJ, Neale MC, Rinker DA, Thompson WK, Tsuang MT, Dale AM, Kremen WS. PMID: 24554725.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    55. Cognitive Symptom Management and Rehabilitation Therapy (CogSMART) for veterans with traumatic brain injury: pilot randomized controlled trial. J Rehabil Res Dev. 2014; 51(1):59-70. Twamley EW, Jak AJ, Delis DC, Bondi MW, Lohr JB. PMID: 24805894.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    56. Neuropsychological criteria for mild cognitive impairment improves diagnostic precision, biomarker associations, and progression rates. J Alzheimers Dis. 2014; 42(1):275-89. Bondi MW, Edmonds EC, Jak AJ, Clark LR, Delano-Wood L, McDonald CR, Nation DA, Libon DJ, Au R, Galasko D, Salmon DP. PMID: 24844687.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansCells
    57. White matter integrity in veterans with mild traumatic brain injury: associations with executive function and loss of consciousness. J Head Trauma Rehabil. 2014 Jan-Feb; 29(1):21-32. Sorg SF, Delano-Wood L, Luc N, Schiehser DM, Hanson KL, Nation DA, Lanni E, Jak AJ, Lu K, Meloy MJ, Frank LR, Lohr JB, Bondi MW. PMID: 23640539.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    58. Increased hippocampal blood flow in sedentary older adults at genetic risk for Alzheimer's disease. J Alzheimers Dis. 2014; 41(3):809-17. Zlatar ZZ, Wierenga CE, Bangen KJ, Liu TT, Jak AJ. PMID: 24685629.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    59. Early identification and heritability of mild cognitive impairment. Int J Epidemiol. 2014 Apr; 43(2):600-10. Kremen WS, Jak AJ, Panizzon MS, Spoon KM, Franz CE, Thompson WK, Jacobson KC, Vasilopoulos T, Vuoksimaa E, Xian H, Toomey R, Lyons MJ. PMID: 24370560.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    60. Conceptual and data-based investigation of genetic influences and brain asymmetry: a twin study of multiple structural phenotypes. J Cogn Neurosci. 2014 May; 26(5):1100-17. Eyler LT, Vuoksimaa E, Panizzon MS, Fennema-Notestine C, Neale MC, Chen CH, Jak A, Franz CE, Lyons MJ, Thompson WK, Spoon KM, Fischl B, Dale AM, Kremen WS. PMID: 24283492.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    61. Are empirically-derived subtypes of mild cognitive impairment consistent with conventional subtypes? J Int Neuropsychol Soc. 2013 Jul; 19(6):635-45. Clark LR, Delano-Wood L, Libon DJ, McDonald CR, Nation DA, Bangen KJ, Jak AJ, Au R, Salmon DP, Bondi MW. PMID: 23552486.
      View in: PubMed   Mentions: 34     Fields:    Translation:Humans
    62. Cognitive reserve moderates the association between hippocampal volume and episodic memory in middle age. Neuropsychologia. 2013 May; 51(6):1124-31. Vuoksimaa E, Panizzon MS, Chen CH, Eyler LT, Fennema-Notestine C, Fiecas MJ, Fischl B, Franz CE, Grant MD, Jak AJ, Lyons MJ, Neale MC, Thompson WK, Tsuang MT, Xian H, Dale AM, Kremen WS. PMID: 23499725.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    63. Efficacy of cognitive rehabilitation therapies for mild cognitive impairment (MCI) in older adults: working toward a theoretical model and evidence-based interventions. Neuropsychol Rev. 2013 Mar; 23(1):63-80. Huckans M, Hutson L, Twamley E, Jak A, Kaye J, Storzbach D. PMID: 23471631.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    64. Crosswords to computers: a critical review of popular approaches to cognitive enhancement. Neuropsychol Rev. 2013 Mar; 23(1):13-26. Jak AJ, Seelye AM, Jurick SM. PMID: 23423553.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    65. Cortical and subcortical cerebrovascular resistance index in mild cognitive impairment and Alzheimer's disease. J Alzheimers Dis. 2013; 36(4):689-98. Nation DA, Wierenga CE, Clark LR, Dev SI, Stricker NH, Jak AJ, Salmon DP, Delano-Wood L, Bangen KJ, Rissman RA, Liu TT, Bondi MW. PMID: 23666173.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    66. A comparison of heritability maps of cortical surface area and thickness and the influence of adjustment for whole brain measures: a magnetic resonance imaging twin study. Twin Res Hum Genet. 2012 Jun; 15(3):304-14. Eyler LT, Chen CH, Panizzon MS, Fennema-Notestine C, Neale MC, Jak A, Jernigan TL, Fischl B, Franz CE, Lyons MJ, Grant M, Prom-Wormley E, Seidman LJ, Tsuang MT, Fiecas MJ, Dale AM, Kremen WS. PMID: 22856366.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    67. A multivariate twin study of hippocampal volume, self-esteem and well-being in middle-aged men. Genes Brain Behav. 2012 Jul; 11(5):539-44. Kubarych TS, Prom-Wormley EC, Franz CE, Panizzon MS, Dale AM, Fischl B, Eyler LT, Fennema-Notestine C, Grant MD, Hauger RL, Hellhammer DH, Jak AJ, Jernigan TL, Lupien SJ, Lyons MJ, Mendoza SP, Neale MC, Seidman LJ, Tsuang MT, Kremen WS. PMID: 22471516.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    68. Effect of mild cognitive impairment and APOE genotype on resting cerebral blood flow and its association with cognition. J Cereb Blood Flow Metab. 2012 Aug; 32(8):1589-99. Wierenga CE, Dev SI, Shin DD, Clark LR, Bangen KJ, Jak AJ, Rissman RA, Liu TT, Salmon DP, Bondi MW. PMID: 22549621.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    69. Hierarchical genetic organization of human cortical surface area. Science. 2012 Mar 30; 335(6076):1634-6. Chen CH, Gutierrez ED, Thompson W, Panizzon MS, Jernigan TL, Eyler LT, Fennema-Notestine C, Jak AJ, Neale MC, Franz CE, Lyons MJ, Grant MD, Fischl B, Seidman LJ, Tsuang MT, Kremen WS, Dale AM. PMID: 22461613.
      View in: PubMed   Mentions: 99     Fields:    Translation:Humans
    70. Genetic and environmental influences of white and gray matter signal contrast: a new phenotype for imaging genetics? Neuroimage. 2012 Apr 15; 60(3):1686-95. Panizzon MS, Fennema-Notestine C, Kubarych TS, Chen CH, Eyler LT, Fischl B, Franz CE, Grant MD, Hamza S, Jak A, Jernigan TL, Lyons MJ, Neale MC, Prom-Wormley EC, Seidman L, Tsuang MT, Wu H, Xian H, Dale AM, Kremen WS. PMID: 22500923.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    71. Antemortem pulse pressure elevation predicts cerebrovascular disease in autopsy-confirmed Alzheimer's disease. J Alzheimers Dis. 2012; 30(3):595-603. Nation DA, Delano-Wood L, Bangen KJ, Wierenga CE, Jak AJ, Hansen LA, Galasko DR, Salmon DP, Bondi MW. PMID: 22451309.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    72. The impact of physical and mental activity on cognitive aging. Curr Top Behav Neurosci. 2012; 10:273-91. Jak AJ. PMID: 21818703.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    73. Posterior cingulum white matter disruption and its associations with verbal memory and stroke risk in mild cognitive impairment. J Alzheimers Dis. 2012; 29(3):589-603. Delano-Wood L, Stricker NH, Sorg SF, Nation DA, Jak AJ, Woods SP, Libon DJ, Delis DC, Frank LR, Bondi MW. PMID: 22466061.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    74. Assessment of Alzheimer's disease risk with functional magnetic resonance imaging: an arterial spin labeling study. J Alzheimers Dis. 2012; 31 Suppl 3:S59-74. Bangen KJ, Restom K, Liu TT, Wierenga CE, Jak AJ, Salmon DP, Bondi MW. PMID: 22531427.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    75. Genetic influences on cortical regionalization in the human brain. Neuron. 2011 Nov 17; 72(4):537-44. Chen CH, Panizzon MS, Eyler LT, Jernigan TL, Thompson W, Fennema-Notestine C, Jak AJ, Neale MC, Franz CE, Hamza S, Lyons MJ, Grant MD, Fischl B, Seidman LJ, Tsuang MT, Kremen WS, Dale AM. PMID: 22099457.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimals
    76. Genetic influences on hippocampal volume differ as a function of testosterone level in middle-aged men. Neuroimage. 2012 Jan 16; 59(2):1123-31. Panizzon MS, Hauger RL, Eaves LJ, Chen CH, Dale AM, Eyler LT, Fischl B, Fennema-Notestine C, Franz CE, Grant MD, Jacobson KC, Jak AJ, Lyons MJ, Mendoza SP, Neale MC, Prom-Wormley E, Seidman LJ, Tsuang MT, Xian H, Kremen WS. PMID: 21983185.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    77. Are self-reported symptoms of executive dysfunction associated with objective executive function performance following mild to moderate traumatic brain injury? J Clin Exp Neuropsychol. 2011 Jul; 33(6):704-14. Schiehser DM, Delis DC, Filoteo JV, Delano-Wood L, Han SD, Jak AJ, Drake AI, Bondi MW. PMID: 21958432.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    78. Stress, exercise, and Alzheimer's disease: a neurovascular pathway. Med Hypotheses. 2011 Jun; 76(6):847-54. Nation DA, Hong S, Jak AJ, Delano-Wood L, Mills PJ, Bondi MW, Dimsdale JE. PMID: 21398043.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    79. Genetic and environmental contributions to regional cortical surface area in humans: a magnetic resonance imaging twin study. Cereb Cortex. 2011 Oct; 21(10):2313-21. Eyler LT, Prom-Wormley E, Panizzon MS, Kaup AR, Fennema-Notestine C, Neale MC, Jernigan TL, Fischl B, Franz CE, Lyons MJ, Grant M, Stevens A, Pacheco J, Perry ME, Schmitt JE, Seidman LJ, Thermenos HW, Tsuang MT, Chen CH, Thompson WK, Jak A, Dale AM, Kremen WS. PMID: 21378112.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimals
    80. Presence of ApoE e4 allele associated with thinner frontal cortex in middle age. J Alzheimers Dis. 2011; 26 Suppl 3:49-60. Fennema-Notestine C, Panizzon MS, Thompson WR, Chen CH, Eyler LT, Fischl B, Franz CE, Grant MD, Jak AJ, Jernigan TL, Lyons MJ, Neale MC, Seidman LJ, Tsuang MT, Xian H, Dale AM, Kremen WS. PMID: 21971450.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    81. Altered brain response for semantic knowledge in Alzheimer's disease. Neuropsychologia. 2011 Feb; 49(3):392-404. Wierenga CE, Stricker NH, McCauley A, Simmons A, Jak AJ, Chang YL, Nation DA, Bangen KJ, Salmon DP, Bondi MW. PMID: 21163275.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    82. Testosterone modifies the effect of APOE genotype on hippocampal volume in middle-aged men. Neurology. 2010 Sep 07; 75(10):874-80. Panizzon MS, Hauger R, Dale AM, Eaves LJ, Eyler LT, Fischl B, Fennema-Notestine C, Franz CE, Grant MD, Jak AJ, Jacobson KC, Lyons MJ, Mendoza SP, Neale MC, Prom-Wormley EC, Seidman LJ, Tsuang MT, Xian H, Kremen WS. PMID: 20819998.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    83. Elevated pulse pressure is associated with age-related decline in language ability. J Int Neuropsychol Soc. 2010 Sep; 16(5):933-8. Nation DA, Wierenga CE, Delano-Wood L, Jak AJ, Delis DC, Salmon DP, Bondi MW. PMID: 20663268.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    84. Hierarchical cognitive and psychosocial predictors of amnestic mild cognitive impairment. J Int Neuropsychol Soc. 2010 Jul; 16(4):721-9. Han SD, Suzuki H, Jak AJ, Chang YL, Salmon DP, Bondi MW. PMID: 20561399.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    85. Complex activities of daily living vary by mild cognitive impairment subtype. J Int Neuropsychol Soc. 2010 Jul; 16(4):630-9. Bangen KJ, Jak AJ, Schiehser DM, Delano-Wood L, Tuminello E, Han SD, Delis DC, Bondi MW. PMID: 20374675.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    86. Heritability of brain ventricle volume: converging evidence from inconsistent results. Neurobiol Aging. 2012 Jan; 33(1):1-8. Kremen WS, Panizzon MS, Neale MC, Fennema-Notestine C, Prom-Wormley E, Eyler LT, Stevens A, Franz CE, Lyons MJ, Grant MD, Jak AJ, Jernigan TL, Xian H, Fischl B, Thermenos HW, Seidman LJ, Tsuang MT, Dale AM. PMID: 20363053.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    87. Increased functional brain response during word retrieval in cognitively intact older adults at genetic risk for Alzheimer's disease. Neuroimage. 2010 Jul 01; 51(3):1222-33. Wierenga CE, Stricker NH, McCauley A, Simmons A, Jak AJ, Chang YL, Delano-Wood L, Bangen KJ, Salmon DP, Bondi MW. PMID: 20298792.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    88. Salivary cortisol and prefrontal cortical thickness in middle-aged men: A twin study. Neuroimage. 2010 Nov 15; 53(3):1093-102. Kremen WS, O'Brien RC, Panizzon MS, Prom-Wormley E, Eaves LJ, Eisen SA, Eyler LT, Hauger RL, Fennema-Notestine C, Fischl B, Grant MD, Hellhammer DH, Jak AJ, Jacobson KC, Jernigan TL, Lupien SJ, Lyons MJ, Mendoza SP, Neale MC, Seidman LJ, Thermenos HW, Tsuang MT, Dale AM, Franz CE. PMID: 20156572.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    89. Heterogeneity in mild cognitive impairment: differences in neuropsychological profile and associated white matter lesion pathology. J Int Neuropsychol Soc. 2009 Nov; 15(6):906-14. Delano-Wood L, Bondi MW, Sacco J, Abeles N, Jak AJ, Libon DJ, Bozoki A. PMID: 19891820.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    90. Profile of hippocampal volumes and stroke risk varies by neuropsychological definition of mild cognitive impairment. J Int Neuropsychol Soc. 2009 Nov; 15(6):890-7. Jak AJ, Urban S, McCauley A, Bangen KJ, Delano-Wood L, Corey-Bloom J, Bondi MW. PMID: 19570306.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    91. Quantification of five neuropsychological approaches to defining mild cognitive impairment. Am J Geriatr Psychiatry. 2009 May; 17(5):368-75. Jak AJ, Bondi MW, Delano-Wood L, Wierenga C, Corey-Bloom J, Salmon DP, Delis DC. PMID: 19390294.
      View in: PubMed   Mentions: 120     Fields:    Translation:Humans
    92. Contributions of neuropsychology and neuroimaging to understanding clinical subtypes of mild cognitive impairment. Int Rev Neurobiol. 2009; 84:81-103. Jak AJ, Bangen KJ, Wierenga CE, Delano-Wood L, Corey-Bloom J, Bondi MW. PMID: 19501714.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    93. Clinical, cognitive, and genetic predictors of change in job status following traumatic brain injury in a military population. J Head Trauma Rehabil. 2009 Jan-Feb; 24(1):57-64. Han SD, Suzuki H, Drake AI, Jak AJ, Houston WS, Bondi MW. PMID: 19158597.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    94. Stroke risk modifies regional white matter differences in mild cognitive impairment. Neurobiol Aging. 2010 Oct; 31(10):1721-31. Delano-Wood L, Bondi MW, Jak AJ, Horne NR, Schweinsburg BC, Frank LR, Wierenga CE, Delis DC, Theilmann RJ, Salmon DP. PMID: 19004528.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    95. Cognitive discrepancies versus APOE genotype as predictors of cognitive decline in normal-functioning elderly individuals: a longitudinal study. Am J Geriatr Psychiatry. 2008 May; 16(5):366-74. Fine EM, Delis DC, Wetter SR, Jacobson MW, Jak AJ, McDonald CR, Braga JC, Thal LJ, Salmon DP, Bondi MW. PMID: 18448849.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    96. Neuropsychological contributions to the early identification of Alzheimer's disease. Neuropsychol Rev. 2008 Mar; 18(1):73-90. Bondi MW, Jak AJ, Delano-Wood L, Jacobson MW, Delis DC, Salmon DP. PMID: 18347989.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    97. Differential age effects on cerebral blood flow and BOLD response to encoding: associations with cognition and stroke risk. Neurobiol Aging. 2009 Aug; 30(8):1276-87. Bangen KJ, Restom K, Liu TT, Jak AJ, Wierenga CE, Salmon DP, Bondi MW. PMID: 18160181.
      View in: PubMed   Mentions: 39     Fields:    Translation:Humans
    98. Differential cross-sectional and longitudinal impact of APOE genotype on hippocampal volumes in nondemented older adults. Dement Geriatr Cogn Disord. 2007; 23(6):382-9. Jak AJ, Houston WS, Nagel BJ, Corey-Bloom J, Bondi MW. PMID: 17389798.
      View in: PubMed   Mentions: 49     Fields:    Translation:Humans
    99. Apolipoprotein E and traumatic brain injury in a military population: evidence of a neuropsychological compensatory mechanism? J Neurol Neurosurg Psychiatry. 2007 Oct; 78(10):1103-8. Han SD, Drake AI, Cessante LM, Jak AJ, Houston WS, Delis DC, Filoteo JV, Bondi MW. PMID: 17287237.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    100. Verbal paired-associate learning by APOE genotype in non-demented older adults: fMRI evidence of a right hemispheric compensatory response. Neurobiol Aging. 2007 Feb; 28(2):238-47. Han SD, Houston WS, Jak AJ, Eyler LT, Nagel BJ, Fleisher AS, Brown GG, Corey-Bloom J, Salmon DP, Thal LJ, Bondi MW. PMID: 16434125.
      View in: PubMed   Mentions: 65     Fields:    Translation:Humans
    101. Verbal memory in mania: effects of clinical state and task requirements. Bipolar Disord. 2003 Oct; 5(5):375-80. Fleck DE, Shear PK, Zimmerman ME, Getz GE, Corey KB, Jak A, Lebowitz BK, Strakowski SM. PMID: 14525560.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    102. Intrapartum maternal fever and neonatal outcome. Pediatrics. 2001 Sep; 108(3):818. Meiron L, Jak A, Shoshana C, Maria Z, Aron Z. PMID: 11548758.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    103. Use of the multiple sclerosis functional composite as an outcome measure in a phase 3 clinical trial. Arch Neurol. 2001 Jun; 58(6):961-7. Cohen JA, Cutter GR, Fischer JS, Goodman AD, Heidenreich FR, Jak AJ, Kniker JE, Kooijmans MF, Lull JM, Sandrock AW, Simon JH, Simonian NA, Whitaker JN. PMID: 11405811.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCTClinical Trials
    104. Intrarater and interrater reliability of the MS functional composite outcome measure. Neurology. 2000 Feb 22; 54(4):802-6. Cohen JA, Fischer JS, Bolibrush DM, Jak AJ, Kniker JE, Mertz LA, Skaramagas TT, Cutter GR. PMID: 10690966.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
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