Mina Nikanjam

Title(s)Associate Physician Diplomate, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    1. Viewing the immune checkpoint VISTA: landscape and outcomes across cancers. ESMO Open. 2024 Mar 18; 9(4):102942. Nishizaki D, Kurzrock R, Miyashita H, Adashek JJ, Lee S, Nikanjam M, Eskander RN, Patel H, Botta GP, Nesline MK, Pabla S, Conroy JM, DePietro P, Sicklick JK, Kato S. PMID: 38503143.
      View in: PubMed   Mentions:
    2. Critical insights into the evolving drug-approval process in China. Cancer. 2024 Mar 01; 130(5):665-667. Nikanjam M, Kurzrock R. PMID: 38165313; PMCID: PMC10922387.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Brief Report: Dolutegravir Plasma Protein Binding and Unbound Concentrations During Pregnancy and Postpartum. J Acquir Immune Defic Syndr. 2023 12 01; 94(4):332-336. Momper JD, Nikanjam M, Best BM, Mirochnick M, Capparelli EV, Cressey TR. PMID: 37884053; PMCID: PMC10686188.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    4. At the right dose: personalised (N-of-1) dosing for precision oncology. Eur J Cancer. 2023 11; 194:113359. Nikanjam M, Kato S, Sicklick JK, Kurzrock R. PMID: 37832506.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Variable Delta-9-Tetrahydrocannabinol Pharmacokinetics and Pharmacodynamics After Cannabis Smoking in Regular Users. Ther Drug Monit. 2023 10 01; 45(5):689-696. Liyanage M, Nikanjam M, Capparelli EV, Suhandynata RT, Fitzgerald RL, Marcotte TD, Grant I, Momper JD. PMID: 37199428.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    6. Dosing of 3 Targeted Agents in Novel Drug Combinations Used at the Precision Medicine Clinic of the University of California San Diego. J Hematol Oncol Pharm. 2023 Feb; 13(1):19-25. Nikanjam M, Tinajero J, McGann M, Li J, Yang J, Shen F, Sicklick JK, Kato S, Capparelli E, Kurzrock R. PMID: 36998525; PMCID: PMC10054256.
      View in: PubMed   Mentions: 2  
    7. Fexofenadine Plasma Concentrations to Estimate Systemic Exposure in Healthy Adults Using a Limited Sampling Strategy with a Population Pharmacokinetic Approach. Ther Drug Monit. 2023 08 01; 45(4):539-545. Piscitelli J, Nikanjam M, Capparelli EV, Blaquera CL, Penzak SR, Nolin TD, Paine MF, Ma JD. PMID: 36645711; PMCID: PMC10123170.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    8. Of Mice, Not Men: When the Bench-to-Bedside Bridge Is Broken. J Immunother Precis Oncol. 2022 Nov; 5(4):87-89. Nikanjam M, Kato S, Kurzrock R. PMID: 36483587; PMCID: PMC9714416.
      View in: PubMed   Mentions: 1  
    9. Liquid biopsy: current technology and clinical applications. J Hematol Oncol. 2022 09 12; 15(1):131. Nikanjam M, Kato S, Kurzrock R. PMID: 36096847; PMCID: PMC9465933.
      View in: PubMed   Mentions: 83     Fields:    Translation:HumansCells
    10. Combination high-dose interleukin-2 and nivolumab for programmed cell death-1 refractory metastatic melanoma: a case series. J Med Case Rep. 2022 Aug 31; 16(1):337. Nikanjam M, Mullen J, Yacoub C, Daniels GA. PMID: 36045435; PMCID: PMC9429475.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    11. Maraviroc Population Pharmacokinetics Within the First 6 Weeks of Life. Pediatr Infect Dis J. 2022 11 01; 41(11):885-890. Liyanage M, Nikanjam M, McFadyen L, Vourvahis M, Rogg L, Moye J, Chadwick EG, Jean-Philippe P, Mirochnick M, Whitson K, Bradford S, Capparelli EV, Best BM. PMID: 35980827; PMCID: PMC9560968.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Impact of CYP2B6 genotype, tuberculosis therapy, and formulation on efavirenz pharmacokinetics in infants and children under 40 months of age. AIDS. 2022 03 15; 36(4):525-532. Nikanjam M, Tran L, Chadwick EG, Bwakura-Dangarembizi M, Bolton Moore C, Samson P, Spector SA, Chakhtoura N, Jean-Philippe P, Frenkel L, Zimmer B, Benns A, Libous J, Capparelli EV. PMID: 34873089; PMCID: PMC8881387.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    13. Optimizing Dolutegravir Initiation in Neonates Using Population Pharmacokinetic Modeling and Simulation. J Acquir Immune Defic Syndr. 2022 01 01; 89(1):108-114. Piscitelli J, Nikanjam M, Best BM, Acosta E, Mirochnick M, Clarke DF, Capparelli EV, Momper JD. PMID: 34629412; PMCID: PMC8665018.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    14. Cetuximab in Patients with Non-Small Cell Lung Cancer and EGFR Exon 20 Insertion Alterations. Clin Oncol Case Rep. 2022 Jan; 5(1). Nikanjam M, Kato S, Adashek JJ, Kurzrock R. PMID: 35403176; PMCID: PMC8994415.
      View in: PubMed   Mentions: 1  
    15. Molecular profiling of advanced malignancies guides first-line N-of-1 treatments in the I-PREDICT treatment-naïve study. Genome Med. 2021 10 04; 13(1):155. Sicklick JK, Kato S, Okamura R, Patel H, Nikanjam M, Fanta PT, Hahn ME, De P, Williams C, Guido J, Solomon BM, McKay RR, Krie A, Boles SG, Ross JS, Lee JJ, Leyland-Jones B, Lippman SM, Kurzrock R. PMID: 34607609; PMCID: PMC8491393.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    16. S-warfarin limited sampling strategy with a population pharmacokinetic approach to estimate exposure and cytochrome P450 (CYP) 2C9 activity in healthy adults. Eur J Clin Pharmacol. 2021 Sep; 77(9):1349-1356. Tran L, Nikanjam M, Capparelli EV, Bertino JS, Nafziger AN, Kashuba ADM, Turpault S, Ma JD. PMID: 33754183.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    17. BRAF V600E/V600K Mutations versus Nonstandard Alterations: Prognostic Implications and Therapeutic Outcomes. Mol Cancer Ther. 2021 06; 20(6):1072-1079. Nikanjam M, Tinajero J, Barkauskas DA, Kurzrock R. PMID: 33722853; PMCID: PMC9264327.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    18. Relationship between tumor mutational burden and maximum standardized uptake value in 2-[18F]FDG PET (positron emission tomography) scan in cancer patients. EJNMMI Res. 2020 Dec 09; 10(1):150. Haghighat Jahromi A, Barkauskas DA, Zabel M, Goodman AM, Frampton G, Nikanjam M, Hoh CK, Kurzrock R. PMID: 33296034; PMCID: PMC7726049.
      View in: PubMed   Mentions: 6  
    19. Model Informed Development of VRC01 in Newborn Infants Using a Population Pharmacokinetics Approach. Clin Pharmacol Ther. 2021 01; 109(1):184-192. Li J, Nikanjam M, Cunningham CK, McFarland EJ, Coates EE, Houser KV, Lin BC, McDermott AB, Flach B, Gama L, Koup RA, Graham BS, Mascola JR, Ledgerwood JE, Capparelli EV. PMID: 32866318; PMCID: PMC7902301.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCellsCTClinical Trials
    20. Real-world data from a molecular tumor board demonstrates improved outcomes with a precision N-of-One strategy. Nat Commun. 2020 10 02; 11(1):4965. Kato S, Kim KH, Lim HJ, Boichard A, Nikanjam M, Weihe E, Kuo DJ, Eskander RN, Goodman A, Galanina N, Fanta PT, Schwab RB, Shatsky R, Plaxe SC, Sharabi A, Stites E, Adashek JJ, Okamura R, Lee S, Lippman SM, Sicklick JK, Kurzrock R. PMID: 33009371; PMCID: PMC7532150.
      View in: PubMed   Mentions: 103     Fields:    Translation:Humans
    21. Clinical implications of plasma circulating tumor DNA in gynecologic cancer patients. Mol Oncol. 2021 01; 15(1):67-79. Charo LM, Eskander RN, Okamura R, Patel SP, Nikanjam M, Lanman RB, Piccioni DE, Kato S, McHale MT, Kurzrock R. PMID: 32881280; PMCID: PMC7782073.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    22. Afebrile Pneumonia in a Patient With Multicentric Castleman Disease on Siltuximab: Infection Without Fever on Anti-Interleukin-6 Therapy. Cureus. 2020 Jul 02; 12(7):e8967. Cohen PR, Nikanjam M, Kato S, Goodman AM, Kurzrock R. PMID: 32766009; PMCID: PMC7398726.
      View in: PubMed   Mentions: 1  
    23. Tumor mutational burden is not predictive of cytotoxic chemotherapy response. Oncoimmunology. 2020 06 24; 9(1):1781997. Nikanjam M, Riviere P, Goodman A, Barkauskas DA, Frampton G, Kurzrock R. PMID: 32923144; PMCID: PMC7458654.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    24. Review of precision cancer medicine: Evolution of the treatment paradigm. Cancer Treat Rev. 2020 Jun; 86:102019. Tsimberidou AM, Fountzilas E, Nikanjam M, Kurzrock R. PMID: 32251926; PMCID: PMC7272286.
      View in: PubMed   Mentions: 178     Fields:    Translation:Humans
    25. Expression of TIM3/VISTA checkpoints and the CD68 macrophage-associated marker correlates with anti-PD1/PDL1 resistance: implications of immunogram heterogeneity. Oncoimmunology. 2020; 9(1):1708065. Kato S, Okamura R, Kumaki Y, Ikeda S, Nikanjam M, Eskander R, Goodman A, Lee S, Glenn ST, Dressman D, Papanicolau-Sengos A, Lenzo FL, Morrison C, Kurzrock R. PMID: 32117584; PMCID: PMC7028323.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    26. Efficacy and safety of anticancer drug combinations: a meta-analysis of randomized trials with a focus on immunotherapeutics and gene-targeted compounds. Oncoimmunology. 2020; 9(1):1710052. Jardim DL, De Melo Gagliato D, Nikanjam M, Barkauskas DA, Kurzrock R. PMID: 32002305; PMCID: PMC6959453.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    27. Development and preclinical pharmacology of a novel dCK inhibitor, DI-87. Biochem Pharmacol. 2020 02; 172:113742. Poddar S, Capparelli EV, Rosser EW, Gipson RM, Wei L, Le T, Jung ME, Radu C, Nikanjam M. PMID: 31812677; PMCID: PMC6981055.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    28. Targeting fusions for improved outcomes in oncology treatment. Cancer. 2020 03 15; 126(6):1315-1321. Nikanjam M, Okamura R, Barkauskas DA, Kurzrock R. PMID: 31794076; PMCID: PMC7050395.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    29. Population pharmacokinetic analysis of high-dose methotrexate in pediatric and adult oncology patients. Cancer Chemother Pharmacol. 2019 12; 84(6):1339-1348. Kawakatsu S, Nikanjam M, Lin M, Le S, Saunders I, Kuo DJ, Capparelli EV. PMID: 31586225.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    30. Relationship between protein biomarkers of chemotherapy response and microsatellite status, tumor mutational burden and PD-L1 expression in cancer patients. Int J Cancer. 2020 06 01; 146(11):3087-3097. Nikanjam M, Arguello D, Gatalica Z, Swensen J, Barkauskas DA, Kurzrock R. PMID: 31479512; PMCID: PMC7051881.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    31. Advanced basal cell cancer: concise review of molecular characteristics and novel targeted and immune therapeutics. Ann Oncol. 2019 10 01; 30(10):1675. Nikanjam M, Cohen PR, Kato S, Sicklick JK, Kurzrock R. PMID: 31408092; PMCID: PMC6857610.
      View in: PubMed   Mentions: 3     Fields:    
    32. Population pharmacokinetics of siltuximab: impact of disease state. Cancer Chemother Pharmacol. 2019 11; 84(5):993-1001. Nikanjam M, Yang J, Capparelli EV. PMID: 31482226; PMCID: PMC6800650.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    33. Midazolam Limited Sampling Strategy With a Population Pharmacokinetic Approach to Simultaneously Estimate Cytochrome P450 (CYP) 3A Constitutive, Inhibition, and Induction/Activation Conditions in Healthy Adults. J Clin Pharmacol. 2019 11; 59(11):1495-1504. Yang J, Nikanjam M, Capparelli EV, Tsunoda SM, Greenberg HE, Penzak SR, Stoch SA, Bertino JS, Nafziger AN, Ma JD. PMID: 31051051.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    34. Evaluation of Omeprazole Limited Sampling Strategies to Estimate Constitutive Cytochrome P450 2C19 Activity in Healthy Adults. Ther Drug Monit. 2018 12; 40(6):754-758. Lin S, Nikanjam M, Capparelli EV, Allegrini A, Pavone D, Yim DS, Hammami MM, Bertino JS, Nafziger AN, Park YS, Kang JS, Yin OQ, Ma JD. PMID: 30045358; PMCID: PMC6237623.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    35. Dosing Oncology Therapeutics in Combination Therapy for Renal Dysfunction: The University of California San Diego Study of Personalized Cancer Therapy to Determine Response and Toxicity (UCSD-PREDICT) Experience. Cureus. 2018 Nov 26; 10(11):e3634. Nikanjam M, Wing J, Capparelli E, Kurzrock R. PMID: 30705793; PMCID: PMC6349570.
      View in: PubMed   Mentions:
    36. Advanced basal cell cancer: concise review of molecular characteristics and novel targeted and immune therapeutics. Ann Oncol. 2018 11 01; 29(11):2192-2199. Nikanjam M, Cohen PR, Kato S, Sicklick JK, Kurzrock R. PMID: 30219896; PMCID: PMC6290882.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    37. Population Pharmacokinetics of Lopinavir/Ritonavir: Changes Across Formulations and Human Development From Infancy Through Adulthood. J Clin Pharmacol. 2018 12; 58(12):1604-1617. Yang J, Nikanjam M, Best BM, Pinto J, Chadwick EG, Daar ES, Havens PL, Rakhmanina N, Capparelli EV. PMID: 30252146; PMCID: PMC6604805.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    38. Vincristine-associated Neuropathy With Antifungal Usage: A Kaiser Northern California Experience. J Pediatr Hematol Oncol. 2018 07; 40(5):e273-e277. Nikanjam M, Sun A, Albers M, Mangalindin K, Song E, Vempaty H, Sam D, Capparelli EV. PMID: 29771861; PMCID: PMC6019195.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    39. Midazolam Single Time Point Concentrations to Estimate Exposure and Cytochrome P450 (CYP) 3A Constitutive Activity Utilizing Limited Sampling Strategy With a Population Pharmacokinetic Approach. J Clin Pharmacol. 2018 09; 58(9):1205-1213. Yang J, Patel M, Nikanjam M, Capparelli EV, Tsunoda SM, Greenberg HE, Penzak SR, Aubrey Stoch S, Bertino JS, Nafziger AN, Ma JD. PMID: 29663428.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    40. Persistent cytarabine and daunorubicin exposure after administration of novel liposomal formulation CPX-351: population pharmacokinetic assessment. Cancer Chemother Pharmacol. 2018 01; 81(1):171-178. Nikanjam M, Capparelli EV, Lancet JE, Louie A, Schiller G. PMID: 29167924; PMCID: PMC5756117.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCTClinical Trials
    41. ATR inhibition facilitates targeting of leukemia dependence on convergent nucleotide biosynthetic pathways. Nat Commun. 2017 08 14; 8(1):241. Le TM, Poddar S, Capri JR, Abt ER, Kim W, Wei L, Uong NT, Cheng CM, Braas D, Nikanjam M, Rix P, Merkurjev D, Zaretsky J, Kornblum HI, Ribas A, Herschman HR, Whitelegge J, Faull KF, Donahue TR, Czernin J, Radu CG. PMID: 28808226; PMCID: PMC5556071.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    42. Dosing immunotherapy combinations: Analysis of 3,526 patients for toxicity and response patterns. Oncoimmunology. 2017; 6(8):e1338997. Nikanjam M, Patel H, Kurzrock R. PMID: 28920006; PMCID: PMC5593707.
      View in: PubMed   Mentions: 21     Fields:    
    43. Dosing Three-Drug Combinations That Include Targeted Anti-Cancer Agents: Analysis of 37,763 Patients. Oncologist. 2017 05; 22(5):576-584. Nikanjam M, Liu S, Yang J, Kurzrock R. PMID: 28424323; PMCID: PMC5423521.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    44. Dosing targeted and cytotoxic two-drug combinations: Lessons learned from analysis of 24,326 patients reported 2010 through 2013. Int J Cancer. 2016 Nov 01; 139(9):2135-41. Nikanjam M, Liu S, Kurzrock R. PMID: 27389805; PMCID: PMC5096042.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    45. Dosing de novo combinations of two targeted drugs: Towards a customized precision medicine approach to advanced cancers. Oncotarget. 2016 Mar 08; 7(10):11310-20. Liu S, Nikanjam M, Kurzrock R. PMID: 26824502; PMCID: PMC4905475.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    46. Population pharmacokinetic analysis of oxaliplatin in adults and children identifies important covariates for dosing. Cancer Chemother Pharmacol. 2015 Mar; 75(3):495-503. Nikanjam M, Stewart CF, Takimoto CH, Synold TW, Beaty O, Fouladi M, Capparelli EV. PMID: 25557868; PMCID: PMC4344382.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    47. Nevirapine exposure with WHO pediatric weight band dosing: enhanced therapeutic concentrations predicted based on extensive international pharmacokinetic experience. Antimicrob Agents Chemother. 2012 Oct; 56(10):5374-80. Nikanjam M, Kabamba D, Cressey TR, Burger D, Aweeka FT, Acosta EP, Spector SA, Capparelli EV. PMID: 22869579; PMCID: PMC3457371.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    48. Assessment of lopinavir pharmacokinetics with respect to developmental changes in infants and the impact on weight band-based dosing. Clin Pharmacol Ther. 2012 Feb; 91(2):243-9. Nikanjam M, Chadwick EG, Robbins B, Alvero C, Palumbo P, Yogev R, Pinto J, Hazra R, Hughes ML, Heckman BE, Capparelli EV, IMPAACT P1030 Team. PMID: 22190064; PMCID: PMC3356582.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    49. Developmental pharmacokinetic changes of Lamivudine in infants and children. J Clin Pharmacol. 2012 Dec; 52(12):1824-32. Tremoulet AH, Nikanjam M, Cressey TR, Chokephaibulkit K, McKinney R, Mirochnick M, Capparelli EV. PMID: 22180560; PMCID: PMC3369109.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    50. Abacavir pharmacokinetics during chronic therapy in HIV-1-infected adolescents and young adults. Clin Pharmacol Ther. 2009 Apr; 85(4):394-401. Sleasman JW, Robbins BL, Cross SJ, Lindsey JC, Kraimer JM, Heckman BE, Sprenger HL, Tustin NB, Rose CH, Poston PA, Neal EF, Pakes GE, Nikanjam M, Capparelli EV. PMID: 19118380; PMCID: PMC2767189.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    51. Synthetic nano-LDL with paclitaxel oleate as a targeted drug delivery vehicle for glioblastoma multiforme. J Control Release. 2007 Dec 20; 124(3):163-71. Nikanjam M, Gibbs AR, Hunt CA, Budinger TF, Forte TM. PMID: 17964677.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    52. Finger flexor motor control patterns during active flexion: an in vivo tendon force study. Hum Mov Sci. 2007 Feb; 26(1):1-10. Nikanjam M, Kursa K, Lehman S, Lattanza L, Diao E, Rempel D. PMID: 17173995.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    53. Synthetic nano-low density lipoprotein as targeted drug delivery vehicle for glioblastoma multiforme. Int J Pharm. 2007 Jan 02; 328(1):86-94. Nikanjam M, Blakely EA, Bjornstad KA, Shu X, Budinger TF, Forte TM. PMID: 16959446.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
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