Jose Onuchic

TitleEmeritus Professor
InstitutionUniversity of California San Diego
Address9500 Gilman Drive #0374
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Haglund E, Nguyen L, Schafer NP, Lammert H, Jennings PA, Onuchic J. Uncovering the molecular mechanisms behind disease-associated leptin variants. J Biol Chem. 2018 Jun 27. PMID: 29950524.
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    2. Sengupta S, Nechushtai R, Jennings PA, Onuchic J, Padilla PA, Azad RK, Mittler R. Phylogenetic analysis of the CDGSH iron-sulfur binding domain reveals its ancient origin. Sci Rep. 2018 Mar 19; 8(1):4840. PMID: 29556009.
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    3. Karmi O, Marjault HB, Pesce L, Carloni P, Onuchic J, Jennings PA, Mittler R, Nechushtai R. The unique fold and lability of the [2Fe-2S] clusters of NEET proteins mediate their key functions in health and disease. J Biol Inorg Chem. 2018 Feb 12. PMID: 29435647.
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    4. Karmi O, Holt SH, Song L, Tamir S, Luo Y, Bai F, Adenwalla A, Darash-Yahana M, Sohn YS, Jennings PA, Azad RK, Onuchic J, Morcos F, Nechushtai R, Mittler R. Interactions between mitoNEET and NAF-1 in cells. PLoS One. 2017; 12(4):e0175796. PMID: 28426722.
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    5. Inupakutika MA, Sengupta S, Nechushtai R, Jennings PA, Onuchic J, Azad RK, Padilla P, Mittler R. Phylogenetic analysis of eukaryotic NEET proteins uncovers a link between a key gene duplication event and the evolution of vertebrates. Sci Rep. 2017 Feb 16; 7:42571. PMID: 28205535.
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    6. Boareto M, Jolly MK, Goldman A, Pietilä M, Mani SA, Sengupta S, Ben-Jacob E, Levine H, Onuchic J. Notch-Jagged signalling can give rise to clusters of cells exhibiting a hybrid epithelial/mesenchymal phenotype. J R Soc Interface. 2016 05; 13(118). PMID: 27170649; PMCID: PMC4892257.
    7. Huang B, Jolly MK, Lu M, Tsarfaty I, Ben-Jacob E, Onuchic J. Modeling the Transitions between Collective and Solitary Migration Phenotypes in Cancer Metastasis. Sci Rep. 2015 Dec 02; 5:17379. PMID: 26627083; PMCID: PMC4667179.
    8. Ben-Jacob E, Lu M, Schultz D, Onuchic J. The physics of bacterial decision making. Front Cell Infect Microbiol. 2014; 4:154. PMID: 25401094; PMCID: PMC4214203.
    9. Tamir S, Paddock ML, Darash-Yahana-Baram M, Holt SH, Sohn YS, Agranat L, Michaeli D, Stofleth JT, Lipper CH, Morcos F, Cabantchik IZ, Onuchic J, Jennings PA, Mittler R, Nechushtai R. Structure-function analysis of NEET proteins uncovers their role as key regulators of iron and ROS homeostasis in health and disease. Biochim Biophys Acta. 2015 Jun; 1853(6):1294-315. PMID: 25448035.
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    10. Lu M, Jolly MK, Onuchic J, Ben-Jacob E. Toward decoding the principles of cancer metastasis circuits. Cancer Res. 2014 Sep 01; 74(17):4574-87. PMID: 25183783.
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    11. Baxter EL, Zuris JA, Wang C, Vo PL, Axelrod HL, Cohen AE, Paddock ML, Nechushtai R, Onuchic J, Jennings PA. Allosteric control in a metalloprotein dramatically alters function. Proc Natl Acad Sci U S A. 2013 Jan 15; 110(3):948-53. PMID: 23271805; PMCID: PMC3549116.
    12. Sulkowska JI, Noel JK, Onuchic J. Energy landscape of knotted protein folding. Proc Natl Acad Sci U S A. 2012 Oct 30; 109(44):17783-8. PMID: 22891304; PMCID: PMC3497829.
    13. Sulkowska JI, Rawdon EJ, Millett KC, Onuchic J, Stasiak A. Conservation of complex knotting and slipknotting patterns in proteins. Proc Natl Acad Sci U S A. 2012 Jun 26; 109(26):E1715-23. PMID: 22685208; PMCID: PMC3387036.
    14. Schug A, Weigt M, Hoch JA, Onuchic J, Hwa T, Szurmant H. Computational modeling of phosphotransfer complexes in two-component signaling. Methods Enzymol. 2010; 471:43-58. PMID: 20946841.
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    15. Mills JE, Whitford PC, Shaffer J, Onuchic J, Adams JA, Jennings PA. A novel disulfide bond in the SH2 Domain of the C-terminal Src kinase controls catalytic activity. J Mol Biol. 2007 Feb 02; 365(5):1460-8. PMID: 17137590; PMCID: PMC2741090.
    16. Onuchic J, Kobayashi C, Miyashita O, Jennings P, Baldridge KK. Exploring biomolecular machines: energy landscape control of biological reactions. Philos Trans R Soc Lond B Biol Sci. 2006 Aug 29; 361(1472):1439-43. PMID: 16873130; PMCID: PMC1647308.
    17. Levy Y, Caflisch A, Onuchic J, Wolynes PG. The folding and dimerization of HIV-1 protease: evidence for a stable monomer from simulations. J Mol Biol. 2004 Jun 25; 340(1):67-79. PMID: 15184023.
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    18. Onuchic J, Wolynes PG. Theory of protein folding. Curr Opin Struct Biol. 2004 Feb; 14(1):70-5. PMID: 15102452.
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