Robert Fahey

Title(s)Emeritus Professor, Chemistry and Biochemistry
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Whole cell and essential enzyme screening assays for mycothiol biosynthesis
    NIH R01AI072133Apr 1, 2007 - Mar 31, 2011
    Role: Principal Investigator
    NIH R01AI049174Aug 1, 2000 - May 31, 2008
    Role: Principal Investigator
    NIH R21AI049174Aug 1, 2000 - May 31, 2004
    Role: Principal Investigator
    NIH R03TW000976Sep 1, 1998 - Aug 31, 2002
    Role: Principal Investigator
    NIH R01AA011393Jul 1, 1996 - Jun 30, 2000
    Role: Principal Investigator
    NIH R01AI036971Sep 30, 1994 - Jul 31, 1998
    Role: Principal Investigator
    NIH R01CA039582Apr 1, 1985 - Jun 30, 1997
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Leaf out times of temperate woody plants are related to phylogeny, deciduousness, growth habit and wood anatomy. New Phytol. 2014 Sep; 203(4):1208-1219. Panchen ZA, Primack RB, Nordt B, Ellwood ER, Stevens AD, Renner SS, Willis CG, Fahey R, Whittemore A, Du Y, Davis CC. PMID: 24942252.
      View in: PubMed   Mentions: 24     Fields:    Translation:Animals
    2. Glutathione analogs in prokaryotes. Biochim Biophys Acta. 2013 May; 1830(5):3182-98. Fahey RC. PMID: 23075826.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansCells
    3. Characterization of BshA, bacillithiol glycosyltransferase from Staphylococcus aureus and Bacillus subtilis. FEBS Lett. 2012 Apr 05; 586(7):1004-8. Upton H, Newton GL, Gushiken M, Lo K, Holden D, Fahey RC, Rawat M. PMID: 22569254; PMCID: PMC3668096.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    4. Detoxification of toxins by bacillithiol in Staphylococcus aureus. Microbiology (Reading). 2012 Apr; 158(Pt 4):1117-1126. Newton GL, Fahey RC, Rawat M. PMID: 22262099; PMCID: PMC3949421.
      View in: PubMed   Mentions: 35     Fields:    Translation:Cells
    5. The DinB superfamily includes novel mycothiol, bacillithiol, and glutathione S-transferases. Biochemistry. 2011 Dec 13; 50(49):10751-60. Newton GL, Leung SS, Wakabayashi JI, Rawat M, Fahey RC. PMID: 22059487; PMCID: PMC3232311.
      View in: PubMed   Mentions: 26     Fields:    Translation:Cells
    6. The Mycobacterium tuberculosis CysQ phosphatase modulates the biosynthesis of sulfated glycolipids and bacterial growth. Bioorg Med Chem Lett. 2011 Sep 01; 21(17):4956-9. Hatzios SK, Schelle MW, Newton GL, Sogi KM, Holsclaw CM, Fahey RC, Bertozzi CR. PMID: 21795043; PMCID: PMC3184767.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    7. Evaluation of NTF1836 as an inhibitor of the mycothiol biosynthetic enzyme MshC in growing and non-replicating Mycobacterium tuberculosis. Bioorg Med Chem. 2011 Jul 01; 19(13):3956-64. Newton GL, Buchmeier N, La Clair JJ, Fahey RC. PMID: 21665483; PMCID: PMC3123436.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    8. Organic hydroperoxide resistance protein and ergothioneine compensate for loss of mycothiol in Mycobacterium smegmatis mutants. J Bacteriol. 2011 Apr; 193(8):1981-90. Ta P, Buchmeier N, Newton GL, Rawat M, Fahey RC. PMID: 21335456; PMCID: PMC3133051.
      View in: PubMed   Mentions: 37     Fields:    Translation:Cells
    9. Biosynthesis and functions of bacillithiol, a major low-molecular-weight thiol in Bacilli. Proc Natl Acad Sci U S A. 2010 Apr 06; 107(14):6482-6. Gaballa A, Newton GL, Antelmann H, Parsonage D, Upton H, Rawat M, Claiborne A, Fahey RC, Helmann JD. PMID: 20308541; PMCID: PMC2851989.
      View in: PubMed   Mentions: 118     Fields:    Translation:Cells
    10. Bacillithiol is an antioxidant thiol produced in Bacilli. Nat Chem Biol. 2009 Sep; 5(9):625-7. Newton GL, Rawat M, La Clair JJ, Jothivasan VK, Budiarto T, Hamilton CJ, Claiborne A, Helmann JD, Fahey RC. PMID: 19578333; PMCID: PMC3510479.
      View in: PubMed   Mentions: 132     Fields:    Translation:Cells
    11. Biosynthesis and functions of mycothiol, the unique protective thiol of Actinobacteria. Microbiol Mol Biol Rev. 2008 Sep; 72(3):471-94. Newton GL, Buchmeier N, Fahey RC. PMID: 18772286; PMCID: PMC2546866.
      View in: PubMed   Mentions: 147     Fields:    Translation:Cells
    12. Unusual production of glutathione in Actinobacteria. Arch Microbiol. 2009 Jan; 191(1):89-93. Johnson T, Newton GL, Fahey RC, Rawat M. PMID: 18719892; PMCID: PMC2605195.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    13. An N-acyl homolog of mycothiol is produced in marine actinomycetes. Arch Microbiol. 2008 Nov; 190(5):547-57. Newton GL, Jensen PR, Macmillan JB, Fenical W, Fahey RC. PMID: 18629474; PMCID: PMC2574923.
      View in: PubMed   Mentions: 7     Fields:    Translation:CellsPHPublic Health
    14. Regulation of mycothiol metabolism by sigma(R) and the thiol redox sensor anti-sigma factor RsrA. Mol Microbiol. 2008 May; 68(4):805-9. Newton GL, Fahey RC. PMID: 18430078.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    15. Mycothiol import by Mycobacterium smegmatis and function as a resource for metabolic precursors and energy production. J Bacteriol. 2007 Oct; 189(19):6796-805. Bzymek KP, Newton GL, Ta P, Fahey RC. PMID: 17644601; PMCID: PMC2045207.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    16. Structure of the type III pantothenate kinase from Bacillus anthracis at 2.0 A resolution: implications for coenzyme A-dependent redox biology. Biochemistry. 2007 Mar 20; 46(11):3234-45. Nicely NI, Parsonage D, Paige C, Newton GL, Fahey RC, Leonardi R, Jackowski S, Mallett TC, Claiborne A. PMID: 17323930; PMCID: PMC2613803.
      View in: PubMed   Mentions: 27     Fields:    Translation:Cells
    17. The mshA gene encoding the glycosyltransferase of mycothiol biosynthesis is essential in Mycobacterium tuberculosis Erdman. FEMS Microbiol Lett. 2006 Nov; 264(1):74-9. Buchmeier N, Fahey RC. PMID: 17020551.
      View in: PubMed   Mentions: 33     Fields:    Translation:Cells
    18. A mycothiol synthase mutant of Mycobacterium tuberculosis has an altered thiol-disulfide content and limited tolerance to stress. J Bacteriol. 2006 Sep; 188(17):6245-52. Buchmeier NA, Newton GL, Fahey RC. PMID: 16923891; PMCID: PMC1595396.
      View in: PubMed   Mentions: 45     Fields:    Translation:Cells
    19. Biochemistry of the initial steps of mycothiol biosynthesis. J Biol Chem. 2006 Nov 10; 281(45):33910-20. Newton GL, Ta P, Bzymek KP, Fahey RC. PMID: 16940050.
      View in: PubMed   Mentions: 33     Fields:    Translation:Cells
    20. Cloning, expression and rapid purification of active recombinant mycothiol ligase as B1 immunoglobulin binding domain of streptococcal protein G, glutathione-S-transferase and maltose binding protein fusion proteins in Mycobacterium smegmatis. Protein Expr Purif. 2006 Nov; 50(1):128-36. Gutierrez-Lugo MT, Newton GL, Fahey RC, Bewley CA. PMID: 16908186.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    21. A coupled spectrophotometric assay for l-cysteine:1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase and its application for inhibitor screening. Anal Biochem. 2006 Jun 15; 353(2):167-73. Newton GL, Ta P, Sareen D, Fahey RC. PMID: 16674910.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    22. Purification and characterization of Mycobacterium tuberculosis 1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, MshB, a mycothiol biosynthetic enzyme. Protein Expr Purif. 2006 Jun; 47(2):542-50. Newton GL, Ko M, Ta P, Av-Gay Y, Fahey RC. PMID: 16630724.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    23. A mycothiol synthase mutant of Mycobacterium smegmatis produces novel thiols and has an altered thiol redox status. J Bacteriol. 2005 Nov; 187(21):7309-16. Newton GL, Ta P, Fahey RC. PMID: 16237013; PMCID: PMC1272995.
      View in: PubMed   Mentions: 24     Fields:    Translation:Cells
    24. Nonprotein thiols and disulfides in rat epididymal spermatozoa and epididymal fluid: role of gamma-glutamyl-transpeptidase in sperm maturation. J Androl. 2005 Sep-Oct; 26(5):629-37; discussion 638-40. Seligman J, Newton GL, Fahey RC, Shalgi R, Kosower NS. PMID: 16088041.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    25. Targeted mutagenesis of the Mycobacterium smegmatis mca gene, encoding a mycothiol-dependent detoxification protein. J Bacteriol. 2004 Sep; 186(18):6050-8. Rawat M, Uppal M, Newton G, Steffek M, Fahey RC, Av-Gay Y. PMID: 15342574; PMCID: PMC515152.
      View in: PubMed   Mentions: 23     Fields:    Translation:Cells
    26. Mycothiol is essential for growth of Mycobacterium tuberculosis Erdman. J Bacteriol. 2003 Nov; 185(22):6736-40. Sareen D, Newton GL, Fahey RC, Buchmeier NA. PMID: 14594852; PMCID: PMC262099.
      View in: PubMed   Mentions: 47     Fields:    Translation:Cells
    27. Characterization of Mycobacterium tuberculosis mycothiol S-conjugate amidase. Biochemistry. 2003 Oct 21; 42(41):12067-76. Steffek M, Newton GL, Av-Gay Y, Fahey RC. PMID: 14556638.
      View in: PubMed   Mentions: 20     Fields:    Translation:Cells
    28. The crystal structure of 1-D-myo-inosityl 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) from Mycobacterium tuberculosis reveals a zinc hydrolase with a lactate dehydrogenase fold. J Biol Chem. 2003 Nov 21; 278(47):47166-70. Maynes JT, Garen C, Cherney MM, Newton G, Arad D, Av-Gay Y, Fahey RC, James MN. PMID: 12958317.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    29. The glycosyltransferase gene encoding the enzyme catalyzing the first step of mycothiol biosynthesis (mshA). J Bacteriol. 2003 Jun; 185(11):3476-9. Newton GL, Koledin T, Gorovitz B, Rawat M, Fahey RC, Av-Gay Y. PMID: 12754249; PMCID: PMC155378.
      View in: PubMed   Mentions: 33     Fields:    Translation:Cells
    30. Association of mycothiol with protection of Mycobacterium tuberculosis from toxic oxidants and antibiotics. Mol Microbiol. 2003 Mar; 47(6):1723-32. Buchmeier NA, Newton GL, Koledin T, Fahey RC. PMID: 12622824.
      View in: PubMed   Mentions: 71     Fields:    Translation:Cells
    31. Inhibition and kinetics of mycobacterium tuberculosis and mycobacterium smegmatis mycothiol-S-conjugate amidase by natural product inhibitors. Bioorg Med Chem. 2003 Feb 20; 11(4):601-8. Nicholas GM, Eckman LL, Newton GL, Fahey RC, Ray S, Bewley CA. PMID: 12538025.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    32. ATP-dependent L-cysteine:1D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, mycothiol biosynthesis enzyme MshC, is related to class I cysteinyl-tRNA synthetases. Biochemistry. 2002 Jun 04; 41(22):6885-90. Sareen D, Steffek M, Newton GL, Fahey RC. PMID: 12033919.
      View in: PubMed   Mentions: 39     Fields:    Translation:Cells
    33. Blood thiols following amifostine and mesna infusions, a pediatric oncology group study. Drug Metab Dispos. 2001 Nov; 29(11):1460-6. Souid AK, Fahey RC, Aktas MK, Sayin OA, Karjoo S, Newton GL, Sadowitz PD, Dubowy RL, Bernstein ML. PMID: 11602522.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    34. Novel thiols of prokaryotes. Annu Rev Microbiol. 2001; 55:333-56. Fahey RC. PMID: 11544359.
      View in: PubMed   Mentions: 78     Fields:    Translation:Cells
    35. N-Acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) is a key enzyme in mycothiol biosynthesis. J Bacteriol. 2000 Dec; 182(24):6958-63. Newton GL, Av-Gay Y, Fahey RC. PMID: 11092856; PMCID: PMC94821.
      View in: PubMed   Mentions: 29     Fields:    Translation:Cells
    36. A novel mycothiol-dependent detoxification pathway in mycobacteria involving mycothiol S-conjugate amidase. Biochemistry. 2000 Sep 05; 39(35):10739-46. Newton GL, Av-Gay Y, Fahey RC. PMID: 10978158.
      View in: PubMed   Mentions: 54     Fields:    Translation:Cells
    37. Improved methods for immunoassay of mycothiol. J Clin Microbiol. 1999 Jul; 37(7):2153-7. Unson MD, Newton GL, Arnold KF, Davis CE, Fahey RC. PMID: 10364578; PMCID: PMC85106.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    38. Radioprotection of human cell nuclear DNA by polyamines: radiosensitivity of chromatin is influenced by tightly bound spermine. Radiat Res. 1999 Mar; 151(3):354-62. Warters RL, Newton GL, Olive PL, Fahey RC. PMID: 10073674.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    39. Characterization of Mycobacterium smegmatis mutants defective in 1-d-myo-inosityl-2-amino-2-deoxy-alpha-d-glucopyranoside and mycothiol biosynthesis. Biochem Biophys Res Commun. 1999 Feb 16; 255(2):239-44. Newton GL, Unson MD, Anderberg SJ, Aguilera JA, Oh NN, delCardayre SB, Av-Gay Y, Fahey RC. PMID: 10049692.
      View in: PubMed   Mentions: 36     Fields:    Translation:Cells
    40. WR-2721 (amifostine) infusion in patients with Ewing's sarcoma receiving ifosfamide and cyclophosphamide with mesna: drug and thiol levels in plasma and blood cells, a Pediatric Oncology Group study. Cancer Chemother Pharmacol. 1999; 44(6):498-504. Souid AK, Fahey RC, Dubowy RL, Newton GL, Bernstein ML. PMID: 10550571.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCellsCTClinical Trials
    41. Mycothiol biosynthesis and metabolism. Cellular levels of potential intermediates in the biosynthesis and degradation of mycothiol in mycobacterium smegmatis. J Biol Chem. 1998 Nov 13; 273(46):30391-7. Anderberg SJ, Newton GL, Fahey RC. PMID: 9804803.
      View in: PubMed   Mentions: 22     Fields:    Translation:Cells
    42. The limits to radioprotection of Chinese hamster V79 cells by WR-1065 under aerobic conditions. Radiat Res. 1998 Jun; 149(6):550-9. Calabro-Jones PM, Aguilera JA, Ward JF, Fahey RC. PMID: 9611093.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    43. An immunoassay for the detection and quantitative determination of mycothiol. J Immunol Methods. 1998 May 01; 214(1-2):29-39. Unson MD, Newton GL, Davis C, Fahey RC. PMID: 9692856.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    44. Coenzyme A disulfide reductase, the primary low molecular weight disulfide reductase from Staphylococcus aureus. Purification and characterization of the native enzyme. J Biol Chem. 1998 Mar 06; 273(10):5744-51. delCardayre SB, Stock KP, Newton GL, Fahey RC, Davies JE. PMID: 9488707.
      View in: PubMed   Mentions: 50     Fields:    Translation:Cells
    45. Import and metabolism of glutathione by Streptococcus mutans. J Bacteriol. 1998 Mar; 180(6):1454-9. Sherrill C, Fahey RC. PMID: 9515913; PMCID: PMC107044.
      View in: PubMed   Mentions: 33     Fields:    Translation:Cells
    46. Determination of the cytoprotective agent WR-2721 (Amifostine, Ethyol) and its metabolites in human blood using monobromobimane fluorescent labeling and high-performance liquid chromatography. Cancer Chemother Pharmacol. 1998; 42(5):400-6. Souid AK, Newton GL, Dubowy RL, Fahey RC, Bernstein ML. PMID: 9771955.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    47. Effect of polyamine-induced compaction and aggregation of DNA on the formation of radiation-induced strand breaks: quantitative models for cellular radiation damage. Radiat Res. 1997 Sep; 148(3):272-84. Newton GL, Aguilera JA, Ward JF, Fahey RC. PMID: 9291359.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    48. Binding of radioprotective thiols and disulfides in Chinese hamster V79 cell nuclei. Radiat Res. 1996 Sep; 146(3):298-305. Newton GL, Aguilera JA, Ward JF, Fahey RC. PMID: 8752308.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    49. Transport of aminothiol radioprotectors into mammalian cells: passive diffusion versus mediated uptake. Radiat Res. 1996 Aug; 146(2):206-15. Newton GL, Aguilera JA, Kim T, Ward JF, Fahey RC. PMID: 8693070.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    50. Glutathione amide and its perthiol in anaerobic sulfur bacteria. J Bacteriol. 1996 Aug; 178(15):4742-6. Bartsch RG, Newton GL, Sherrill C, Fahey RC. PMID: 8755912; PMCID: PMC178251.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    51. Polyamine-induced compaction and aggregation of DNA--a major factor in radioprotection of chromatin under physiological conditions. Radiat Res. 1996 Jun; 145(6):776-80. Newton GL, Aguilera JA, Ward JF, Fahey RC. PMID: 8643839.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    52. Distribution of thiols in microorganisms: mycothiol is a major thiol in most actinomycetes. J Bacteriol. 1996 Apr; 178(7):1990-5. Newton GL, Arnold K, Price MS, Sherrill C, Delcardayre SB, Aharonowitz Y, Cohen G, Davies J, Fahey RC, Davis C. PMID: 8606174; PMCID: PMC177895.
      View in: PubMed   Mentions: 184     Fields:    Translation:Cells
    53. DNA repair by thiols in air shows two radicals make a double-strand break. Radiat Res. 1995 Sep; 143(3):273-80. Milligan JR, Ng JY, Wu CC, Aguilera JA, Fahey RC, Ward JF. PMID: 7652164.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    54. The structure of U17 isolated from Streptomyces clavuligerus and its properties as an antioxidant thiol. Eur J Biochem. 1995 Jun 01; 230(2):821-5. Newton GL, Bewley CA, Dwyer TJ, Horn R, Aharonowitz Y, Cohen G, Davies J, Faulkner DJ, Fahey RC. PMID: 7607257.
      View in: PubMed   Mentions: 34     Fields:    Translation:Cells
    55. Role of charge in the radioprotection of E. coli by thiols. Int J Radiat Biol. 1995 Apr; 67(4):393-401. Prise KM, Gillies NE, Whelan A, Newton GL, Fahey RC, Michael BD. PMID: 7738402.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    56. Thiol and disulfide metabolites of the radiation protector and potential chemopreventive agent WR-2721 are linked to both its anti-cytotoxic and anti-mutagenic mechanisms of action. Carcinogenesis. 1995 Apr; 16(4):767-74. Grdina DJ, Shigematsu N, Dale P, Newton GL, Aguilera JA, Fahey RC. PMID: 7728953.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    57. Determination of biothiols by bromobimane labeling and high-performance liquid chromatography. Methods Enzymol. 1995; 251:148-66. Newton GL, Fahey RC. PMID: 7651194.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    58. Low-molecular-weight thiols in streptomycetes and their potential role as antioxidants. J Bacteriol. 1993 May; 175(9):2734-42. Newton GL, Fahey RC, Cohen G, Aharonowitz Y. PMID: 8478335; PMCID: PMC204577.
      View in: PubMed   Mentions: 27     Fields:    Translation:Cells
    59. Determination of the acid dissociation constants for WR-1065 by proton NMR spectroscopy. Radiat Res. 1992 Aug; 131(2):143-51. Newton GL, Dwyer TJ, Kim T, Ward JF, Fahey RC. PMID: 1641468.
      View in: PubMed   Mentions: 1     Fields:    
    60. Thiol uptake by Chinese hamster V79 cells and aerobic radioprotection as a function of the net charge on the thiol. Radiat Res. 1992 May; 130(2):194-204. Aguilera JA, Newton GL, Fahey RC, Ward JF. PMID: 1574575.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    61. Aerobic radioprotection of pBR322 by thiols: effect of thiol net charge upon scavenging of hydroxyl radicals and repair of DNA radicals. Radiat Res. 1992 May; 130(2):183-93. Zheng S, Newton GL, Ward JF, Fahey RC. PMID: 1574574.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    62. para-sulfobenzoyloxybromobimane: a new membrane-impermeable reagent useful for the analysis of thiols and their export from cells. Anal Biochem. 1992 Feb 14; 201(1):30-42. Newton GL, Aguilera JA, Fahey RC, Ward JF, Radkowsky AE, Kosower EM. PMID: 1621960.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    63. The role of charge in intracellular radioprotection by thiols. BJR Suppl. 1992; 24:32-4. Gillies NE, Prise KM, Michael BD, Fahey RC. PMID: 1290708.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    64. The effects of counter-ion condensation and co-ion depletion upon the rates of chemical repair of poly(U) radicals by thiols. Int J Radiat Biol. 1991 Apr; 59(4):885-99. Fahey RC, Vojnovic B, Michael BD. PMID: 1674274.
      View in: PubMed   Mentions: 1     Fields:    
    65. Rates for repair of pBR 322 DNA radicals by thiols as measured by the gas explosion technique: evidence that counter-ion condensation and co-ion depletion are significant at physiological ionic strength. Int J Radiat Biol. 1991 Apr; 59(4):901-17. Fahey RC, Prise KM, Stratford MR, Watfa RR, Michael BD. PMID: 1674275.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    66. Evolution of glutathione metabolism. Adv Enzymol Relat Areas Mol Biol. 1991; 64:1-53. Fahey RC, Sundquist AR. PMID: 1675828.
      View in: PubMed   Mentions: 48     Fields:    Translation:Animals
    67. Nuclear thiols: technical limitations on the determination of endogenous nuclear glutathione and the potential importance of sulfhydryl proteins. Radiat Res. 1990 Jan; 121(1):98-106. Loh SN, Dethlefsen LA, Newton GL, Aguilera JA, Fahey RC. PMID: 2300674.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    68. Evolution of antioxidant mechanisms: thiol-dependent peroxidases and thioltransferase among procaryotes. J Mol Evol. 1989 Nov; 29(5):429-35. Sundquist AR, Fahey RC. PMID: 2515292.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    69. The function of gamma-glutamylcysteine and bis-gamma-glutamylcystine reductase in Halobacterium halobium. J Biol Chem. 1989 Jan 15; 264(2):719-25. Sundquist AR, Fahey RC. PMID: 2910862.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    70. The novel disulfide reductase bis-gamma-glutamylcystine reductase and dihydrolipoamide dehydrogenase from Halobacterium halobium: purification by immobilized-metal-ion affinity chromatography and properties of the enzymes. J Bacteriol. 1988 Aug; 170(8):3459-67. Sundquist AR, Fahey RC. PMID: 3136140; PMCID: PMC211315.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    71. Uptake of WR-2721 derivatives by cells in culture: identification of the transported form of the drug. Cancer Res. 1988 Jul 01; 48(13):3634-40. Calabro-Jones PM, Aguilera JA, Ward JF, Smoluk GD, Fahey RC. PMID: 2837319.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    72. Radioprotection of cells in culture by WR-2721 and derivatives: form of the drug responsible for protection. Cancer Res. 1988 Jul 01; 48(13):3641-7. Smoluk GD, Fahey RC, Calabro-Jones PM, Aguilera JA, Ward JF. PMID: 2837320.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    73. Radioprotection of DNA by thiols: relationship between the net charge on a thiol and its ability to protect DNA. Radiat Res. 1988 Apr; 114(1):11-27. Zheng S, Newton GL, Gonick G, Fahey RC, Ward JF. PMID: 3127858.
      View in: PubMed   Mentions: 14     Fields:    
    74. Interaction of glutathione and other low-molecular-weight thiols with DNA: evidence for counterion condensation and coion depletion near DNA. Radiat Res. 1988 Apr; 114(1):3-10. Smoluk GD, Fahey RC, Ward JF. PMID: 3127859.
      View in: PubMed   Mentions: 3     Fields:    
    75. Protection of DNA by thiols. Pharmacol Ther. 1988; 39(1-3):101-8. Fahey RC. PMID: 3059361.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    76. Determination of low-molecular-weight thiols using monobromobimane fluorescent labeling and high-performance liquid chromatography. Methods Enzymol. 1987; 143:85-96. Fahey RC, Newton GL. PMID: 3657565.
      View in: PubMed   Mentions: 81     Fields:    
    77. Purification of thiols from biological samples. Methods Enzymol. 1987; 143:96-101. Newton GL, Fahey RC. PMID: 3657566.
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    78. The evolution of glutathione metabolism in phototrophic microorganisms. J Mol Evol. 1987; 25:81-8. Fahey RC, Buschbacher RM, Newton GL. PMID: 11542078.
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    79. Determination of thiol proteins using monobromobimane labeling and high-performance liquid chromatographic analysis: application to Escherichia coli thioredoxin. Anal Biochem. 1986 Nov 15; 159(1):143-9. Chinn PC, Pigiet V, Fahey RC. PMID: 3544950.
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    80. Equilibrium dialysis studies of the binding of radioprotector compounds to DNA. Radiat Res. 1986 Aug; 107(2):194-204. Smoluk GD, Fahey RC, Ward JF. PMID: 3018831.
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    81. Analysis of biological thiols: determination of thiol components of disulfides and thioesters. Anal Biochem. 1986 Apr; 154(1):34-42. Fenton SS, Fahey RC. PMID: 2939769.
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    82. Measurement of WR-2721, WR-1065, and WR-33278 in plasma. Int J Radiat Oncol Biol Phys. 1985 Jun; 11(6):1193-7. Fahey RC, Newton GL. PMID: 2987166.
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    83. Alkaline phosphatase promotes radioprotection and accumulation of WR-1065 in V79-171 cells incubated in medium containing WR-2721. Int J Radiat Biol Relat Stud Phys Chem Med. 1985 Jan; 47(1):23-7. Calabro-Jones PM, Fahey RC, Smoluk GD, Ward JF. PMID: 2982751.
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    84. Pharmacokinetics of WR-1065 in mouse tissue following treatment with WR-2721. Int J Radiat Oncol Biol Phys. 1984 Sep; 10(9):1525-8. Utley JF, Seaver N, Newton GL, Fahey RC. PMID: 6090355.
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    85. Entamoeba histolytica: a eukaryote without glutathione metabolism. Science. 1984 Apr 06; 224(4644):70-2. Fahey RC, Newton GL, Arrick B, Overdank-Bogart T, Aley SB. PMID: 6322306.
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    86. Levels of sulfhydryls and disulfides in proteins from Neurospora crassa conidia and mycelia. J Bacteriol. 1983 Nov; 156(2):703-9. Brody S, Mikolajczyk SD, Fahey RC. PMID: 6226648; PMCID: PMC217886.
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    87. Analysis of biological thiols: derivatization with monobromobimane and separation by reverse-phase high-performance liquid chromatography. Anal Biochem. 1981 Jul 01; 114(2):383-7. Newton GL, Dorian R, Fahey RC. PMID: 7304929.
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    88. Analysis of biological thiols: quantitative determination of thiols at the picomole level based upon derivatization with monobromobimanes and separation by cation-exchange chromatography. Anal Biochem. 1981 Mar 01; 111(2):357-65. Fahey RC, Newton GL, Dorian R, Kosower EM. PMID: 7247030.
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    89. Analysis of biological thiols: derivatization with monobromotrimethylammoniobimane and characterization by electrophoresis and chromatography. Anal Biochem. 1980 Sep 01; 107(1):1-10. Fahey RC, Newton GL, Dorian R, Kosower EM. PMID: 6449160.
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    90. Role of hydration state and thiol-disulfide status in the control of thermal stability and protein synthesis in wheat embryo. Plant Physiol. 1980 Jun; 65(6):1062-6. Fahey RC, Di Stefano DL, Meier GP, Bryan RN. PMID: 16661331; PMCID: PMC440481.
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    91. Correlation of enzymatic activity and thermal resistance with hydration state in ungerminated Neurospora conidia. J Bacteriol. 1978 Sep; 135(3):868-75. Fahey RC, Mikolajczyk SD, Brody S. PMID: 151096; PMCID: PMC222458.
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    92. Occurrence of glutathione in bacteria. J Bacteriol. 1978 Mar; 133(3):1126-9. Fahey RC, Brown WC, Adams WB, Worsham MB. PMID: 417060; PMCID: PMC222142.
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    93. On the cysteine and cystine content of proteins. Differences between intracellular and extracellular proteins. J Mol Evol. 1977 Nov 25; 10(2):155-60. Fahey RC, Hunt JS, Windham GC. PMID: 592421.
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    94. The glutathione thiol-disulfide status in the sea urchin egg during fertilization and the first cell division cycle. Biochim Biophys Acta. 1976 Jul 21; 437(2):445-53. Fahey RC, Mikolajczyk SD, Meier GP, Epel D, Carroll EJ. PMID: 952928.
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    95. Changes in the glutathione thiol-disulfide status of Neurospora crassa conidia during germination and aging. J Bacteriol. 1975 Jan; 121(1):144-51. Fahey RC, Brody S, Mikolajczyk SD. PMID: 123243; PMCID: PMC285624.
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    96. A nonenzyme-coupled assay for triosephosphate isomerase based upon circular dichroism of glyceraldehyde-3-phosphate. Anal Biochem. 1974 Feb; 57(2):547-54. Fahey RC, Fischer EF. PMID: 4819742.
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