Loading...

Stephanie Stanford

Title(s)Assistant Adjunct Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
vCardDownload vCard

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. PTPN2 links colonic and joint inflammation in experimental autoimmune arthritis. JCI Insight. 2020 Oct 15; 5(20). Hsieh WC, Svensson MN, Zoccheddu M, Tremblay ML, Sakaguchi S, Stanford SM, Bottini N. PMID: 33055428.
      View in: PubMed   Mentions:    Fields:    
    2. Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal. Sci Adv. 2020 Jun; 6(26):eaba4353. Svensson MND, Zoccheddu M, Yang S, Nygaard G, Secchi C, Doody KM, Slowikowski K, Mizoguchi F, Humby F, Hands R, Santelli E, Sacchetti C, Wakabayashi K, Wu DJ, Barback C, Ai R, Wang W, Sims GP, Mydel P, Kasama T, Boyle DL, Galimi F, Vera D, Tremblay ML, Raychaudhuri S, Brenner MB, Firestein GS, Pitzalis C, Ekwall AH, Stanford SM, Bottini N. PMID: 32637608.
      View in: PubMed   Mentions:    Fields:    
    3. PTPN22 phosphorylation acts as a molecular rheostat for the inhibition of TCR signaling. Sci Signal. 2020 Mar 17; 13(623). Yang S, Svensson MND, Harder NHO, Hsieh WC, Santelli E, Kiosses WB, Moresco JJ, Yates JR, King CC, Liu L, Stanford SM, Bottini N. PMID: 32184287.
      View in: PubMed   Mentions:    Fields:    
    4. RPTPa phosphatase activity is allosterically regulated by the membrane-distal catalytic domain. J Biol Chem. 2020 Apr 10; 295(15):4923-4936. Wen Y, Yang S, Wakabayashi K, Svensson MND, Stanford SM, Santelli E, Bottini N. PMID: 32139509.
      View in: PubMed   Mentions: 1     Fields:    
    5. Secreted Protein Acidic and Rich in Cysteine Mediated Biomimetic Delivery of Methotrexate by Albumin-Based Nanomedicines for Rheumatoid Arthritis Therapy. ACS Nano. 2019 05 28; 13(5):5036-5048. Liu L, Hu F, Wang H, Wu X, Eltahan AS, Stanford S, Bottini N, Xiao H, Bottini M, Guo W, Liang XJ. PMID: 30978282.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    6. The Contribution of PTPN22 to Rheumatic Disease. Arthritis Rheumatol. 2019 04; 71(4):486-495. Mustelin T, Bottini N, Stanford SM. PMID: 30507064.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    7. PTPN14 phosphatase and YAP promote TGFß signalling in rheumatoid synoviocytes. Ann Rheum Dis. 2019 05; 78(5):600-609. Bottini A, Wu DJ, Ai R, Le Roux M, Bartok B, Bombardieri M, Doody KM, Zhang V, Sacchetti C, Zoccheddu M, Lonic A, Li X, Boyle DL, Hammaker D, Meng TC, Liu L, Corr M, Stanford SM, Lewis M, Wang W, Firestein GS, Khew-Goodall Y, Pitzalis C, Bottini N. PMID: 30808624.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    8. PTP4A1 promotes TGFß signaling and fibrosis in systemic sclerosis. Nat Commun. 2017 10 20; 8(1):1060. Sacchetti C, Bai Y, Stanford SM, Di Benedetto P, Cipriani P, Santelli E, Piera-Velazquez S, Chernitskiy V, Kiosses WB, Ceponis A, Kaestner KH, Boin F, Jimenez SA, Giacomelli R, Zhang ZY, Bottini N. PMID: 29057934.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    9. Targeting Tyrosine Phosphatases: Time to End the Stigma. Trends Pharmacol Sci. 2017 06; 38(6):524-540. Stanford SM, Bottini N. PMID: 28412041.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    10. Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase. Nat Chem Biol. 2017 06; 13(6):624-632. Stanford SM, Aleshin AE, Zhang V, Ardecky RJ, Hedrick MP, Zou J, Ganji SR, Bliss MR, Yamamoto F, Bobkov AA, Kiselar J, Liu Y, Cadwell GW, Khare S, Yu J, Barquilla A, Chung TDY, Mustelin T, Schenk S, Bankston LA, Liddington RC, Pinkerton AB, Bottini N. PMID: 28346406.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    11. Abnormal PTPN11 enhancer methylation promotes rheumatoid arthritis fibroblast-like synoviocyte aggressiveness and joint inflammation. JCI Insight. 2016 May 19; 1(7). Maeshima K, Stanford SM, Hammaker D, Sacchetti C, Zeng LF, Ai R, Zhang V, Boyle DL, Aleman Muench GR, Feng GS, Whitaker JW, Zhang ZY, Wang W, Bottini N, Firestein GS. PMID: 27275015.
      View in: PubMed   Mentions: 10     Fields:    
    12. T-helper signals restore B-cell receptor signaling in autoreactive anergic B cells by upregulating CD45 phosphatase activity. J Allergy Clin Immunol. 2016 09; 138(3):839-851.e8. Szodoray P, Stanford SM, Molberg Ø, Munthe LA, Bottini N, Nakken B. PMID: 27056269.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    13. Receptor Protein Tyrosine Phosphatase a-Mediated Enhancement of Rheumatoid Synovial Fibroblast Signaling and Promotion of Arthritis in Mice. Arthritis Rheumatol. 2016 Feb; 68(2):359-69. Stanford SM, Svensson MN, Sacchetti C, Pilo CA, Wu DJ, Kiosses WB, Hellvard A, Bergum B, Muench GR, Elly C, Liu YC, den Hertog J, Elson A, Sap J, Mydel P, Boyle DL, Corr M, Firestein GS, Bottini N. PMID: 26414708.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    14. Ptpn22 and Cd2 Variations Are Associated with Altered Protein Expression and Susceptibility to Type 1 Diabetes in Nonobese Diabetic Mice. J Immunol. 2015 Nov 15; 195(10):4841-52. Fraser HI, Howlett S, Clark J, Rainbow DB, Stanford SM, Wu DJ, Hsieh YW, Maine CJ, Christensen M, Kuchroo V, Sherman LA, Podolin PL, Todd JA, Steward CA, Peterson LB, Bottini N, Wicker LS. PMID: 26438525.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    15. Deletion of low molecular weight protein tyrosine phosphatase (Acp1) protects against stress-induced cardiomyopathy. J Pathol. 2015 Dec; 237(4):482-94. Wade F, Quijada P, Al-Haffar KM, Awad SM, Kunhi M, Toko H, Marashly Q, Belhaj K, Zahid I, Al-Mohanna F, Stanford SM, Alvarez R, Liu Y, Colak D, Jordan MC, Roos KP, Assiri A, Al-Habeeb W, Sussman M, Bottini N, Poizat C. PMID: 26213100.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    16. Phosphatase Inhibitors Function as Novel, Broad Spectrum Botulinum Neurotoxin Antagonists in Mouse and Human Embryonic Stem Cell-Derived Motor Neuron-Based Assays. PLoS One. 2015; 10(6):e0129264. Kiris E, Nuss JE, Stanford SM, Wanner LM, Cazares L, Maestre MF, Du HT, Gomba GY, Burnett JC, Gussio R, Bottini N, Panchal RG, Kane CD, Tessarollo L, Bavari S. PMID: 26061731.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    17. Targeting phosphatase-dependent proteoglycan switch for rheumatoid arthritis therapy. Sci Transl Med. 2015 May 20; 7(288):288ra76. Doody KM, Stanford SM, Sacchetti C, Svensson MN, Coles CH, Mitakidis N, Kiosses WB, Bartok B, Fos C, Cory E, Sah RL, Liu-Bryan R, Boyle DL, Arnett HA, Mustelin T, Corr M, Esko JD, Tremblay ML, Firestein GS, Aricescu AR, Bottini N. PMID: 25995222.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    18. TGFß responsive tyrosine phosphatase promotes rheumatoid synovial fibroblast invasiveness. Ann Rheum Dis. 2016 Jan; 75(1):295-302. Stanford SM, Aleman Muench GR, Bartok B, Sacchetti C, Kiosses WB, Sharma J, Maestre MF, Bottini M, Mustelin T, Boyle DL, Firestein GS, Bottini N. PMID: 25378349.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    19. Ion channel TRPV1-dependent activation of PTP1B suppresses EGFR-associated intestinal tumorigenesis. J Clin Invest. 2014 Sep; 124(9):3793-806. de Jong PR, Takahashi N, Harris AR, Lee J, Bertin S, Jeffries J, Jung M, Duong J, Triano AI, Lee J, Niv Y, Herdman DS, Taniguchi K, Kim CW, Dong H, Eckmann L, Stanford SM, Bottini N, Corr M, Raz E. PMID: 25083990.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    20. PTPN22: the archetypal non-HLA autoimmunity gene. Nat Rev Rheumatol. 2014 Oct; 10(10):602-11. Stanford SM, Bottini N. PMID: 25003765.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimalsCells
    21. Cellular biochemistry methods for investigating protein tyrosine phosphatases. Antioxid Redox Signal. 2014 May 10; 20(14):2160-78. Stanford SM, Ahmed V, Barrios AM, Bottini N. PMID: 24294920.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    22. Autoimmunity-associated LYP-W620 does not impair thymic negative selection of autoreactive T cells. PLoS One. 2014; 9(2):e86677. Wu DJ, Zhou W, Enouz S, Orrú V, Stanford SM, Maine CJ, Rapini N, Sawatzke K, Engel I, Fiorillo E, Sherman LA, Kronenberg M, Zehn D, Peterson E, Bottini N. PMID: 24498279.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    23. Substrate selection influences molecular recognition in a screen for lymphoid tyrosine phosphatase inhibitors. Chembiochem. 2013 Sep 02; 14(13):1640-7. Kulkarni RA, Vellore NA, Bliss MR, Stanford SM, Falk MD, Bottini N, Baron R, Barrios AM. PMID: 23956195.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    24. pCAP-based peptide substrates: the new tool in the box of tyrosine phosphatase assays. Methods. 2014 Jan 15; 65(2):165-74. Stanford SM, Krishnamurthy D, Kulkarni RA, Karver CE, Bruenger E, Walker LM, Ma CT, Chung TD, Sergienko E, Bottini N, Barrios AM. PMID: 23886911.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    25. Thiuram disulfides as pseudo-irreversible inhibitors of lymphoid tyrosine phosphatase. ChemMedChem. 2013 Sep; 8(9):1561-8. Kulkarni RA, Stanford SM, Vellore NA, Krishnamurthy D, Bliss MR, Baron R, Bottini N, Barrios AM. PMID: 23873737.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    26. The autoimmunity-associated gene PTPN22 potentiates toll-like receptor-driven, type 1 interferon-dependent immunity. Immunity. 2013 Jul 25; 39(1):111-22. Wang Y, Shaked I, Stanford SM, Zhou W, Curtsinger JM, Mikulski Z, Shaheen ZR, Cheng G, Sawatzke K, Campbell AM, Auger JL, Bilgic H, Shoyama FM, Schmeling DO, Balfour HH, Hasegawa K, Chan AC, Corbett JA, Binstadt BA, Mescher MF, Ley K, Bottini N, Peterson EJ. PMID: 23871208.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansAnimalsCells
    27. A potent and selective small-molecule inhibitor for the lymphoid-specific tyrosine phosphatase (LYP), a target associated with autoimmune diseases. J Med Chem. 2013 Jun 27; 56(12):4990-5008. He Y, Liu S, Menon A, Stanford S, Oppong E, Gunawan AM, Wu L, Wu DJ, Barrios AM, Bottini N, Cato AC, Zhang ZY. PMID: 23713581.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    28. Protein tyrosine phosphatase expression profile of rheumatoid arthritis fibroblast-like synoviocytes: a novel role of SH2 domain-containing phosphatase 2 as a modulator of invasion and survival. Arthritis Rheum. 2013 May; 65(5):1171-80. Stanford SM, Maestre MF, Campbell AM, Bartok B, Kiosses WB, Boyle DL, Arnett HA, Mustelin T, Firestein GS, Bottini N. PMID: 23335101.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    29. Regulation of TCR signalling by tyrosine phosphatases: from immune homeostasis to autoimmunity. Immunology. 2012 Sep; 137(1):1-19. Stanford SM, Rapini N, Bottini N. PMID: 22862552.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    30. High-throughput screen using a single-cell tyrosine phosphatase assay reveals biologically active inhibitors of tyrosine phosphatase CD45. Proc Natl Acad Sci U S A. 2012 Aug 28; 109(35):13972-7. Stanford SM, Panchal RG, Walker LM, Wu DJ, Falk MD, Mitra S, Damle SS, Ruble D, Kaltcheva T, Zhang S, Zhang ZY, Bavari S, Barrios AM, Bottini N. PMID: 22891353.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    31. PTPN22 alters the development of regulatory T cells in the thymus. J Immunol. 2012 Jun 01; 188(11):5267-75. Maine CJ, Hamilton-Williams EE, Cheung J, Stanford SM, Bottini N, Wicker LS, Sherman LA. PMID: 22539785.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    32. Discovery of a novel series of inhibitors of lymphoid tyrosine phosphatase with activity in human T cells. J Med Chem. 2011 Mar 24; 54(6):1640-54. Stanford SM, Krishnamurthy D, Falk MD, Messina R, Debnath B, Li S, Liu T, Kazemi R, Dahl R, He Y, Yu X, Chan AC, Zhang ZY, Barrios AM, Woods VL, Neamati N, Bottini N. PMID: 21341673.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    33. Carbon nanotube-based nanocarriers: the importance of keeping it clean. J Nanosci Nanotechnol. 2010 Aug; 10(8):5293-301. Delogu LG, Stanford SM, Santelli E, Magrini A, Bergamaschi A, Motamedchaboki K, Rosato N, Mustelin T, Bottini N, Bottini M. PMID: 21125885.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCellsPHPublic Health
    34. Autoimmune-associated PTPN22 R620W variation reduces phosphorylation of lymphoid phosphatase on an inhibitory tyrosine residue. J Biol Chem. 2010 Aug 20; 285(34):26506-18. Fiorillo E, Orrú V, Stanford SM, Liu Y, Salek M, Rapini N, Schenone AD, Saccucci P, Delogu LG, Angelini F, Manca Bitti ML, Schmedt C, Chan AC, Acuto O, Bottini N. PMID: 20538612.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    35. Lymphoid tyrosine phosphatase and autoimmunity: human genetics rediscovers tyrosine phosphatases. Semin Immunopathol. 2010 Jun; 32(2):127-36. Stanford SM, Mustelin TM, Bottini N. PMID: 20204370.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    36. Regulation of lymphoid tyrosine phosphatase activity: inhibition of the catalytic domain by the proximal interdomain. Biochemistry. 2009 Aug 11; 48(31):7525-32. Liu Y, Stanford SM, Jog SP, Fiorillo E, Orrú V, Comai L, Bottini N. PMID: 19586056.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    37. A loss-of-function variant of PTPN22 is associated with reduced risk of systemic lupus erythematosus. Hum Mol Genet. 2009 Feb 01; 18(3):569-79. Orrú V, Tsai SJ, Rueda B, Fiorillo E, Stanford SM, Dasgupta J, Hartiala J, Zhao L, Ortego-Centeno N, D'Alfonso S, Arnett FC, Wu H, Gonzalez-Gay MA, Tsao BP, Pons-Estel B, Alarcon-Riquelme ME, He Y, Zhang ZY, Allayee H, Chen XS, Martin J, Bottini N. PMID: 18981062.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansCells
    38. Gold(I)-mediated inhibition of protein tyrosine phosphatases: a detailed in vitro and cellular study. J Med Chem. 2008 Aug 14; 51(15):4790-5. Krishnamurthy D, Karver MR, Fiorillo E, Orrú V, Stanford SM, Bottini N, Barrios AM. PMID: 18605719.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    Stephanie's Networks
    Concepts (238)
    Derived automatically from this person's publications.
    _
    Co-Authors (22)
    People in Profiles who have published with this person.
    _
    Similar People (60)
    People who share similar concepts with this person.
    _
    Same Department
    Search Department
    _