Hoi U

Title(s)Professor, Surgery
SchoolHealth Sciences
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    Dr. Hoi Sang U joined the faculty of UCSD in 1978. Dr. U, serving as Professor of Neurological Surgery, was appointed the Vice-Chief of Academic Affairs for the division of Neurological Surgery in 1995. He has an extensive background in all aspects of neurosurgery, including neurovascular, skull base, and transsphenoidal surgery.

    Dr. U is an internationally recognized specialist in the treatment of the vascular anomalies known as AVMs. Patients have traveled to UCSD from as far away as Australia, Hong Kong, and the Sultanate of Brunei to take advantage of his expertise. His neurovascular practice also includes treatment of aneurysms and cavernous hemangiomas. He collaborates closely with interventional neuroradiologists Dr. Charles Kerber and Dr. Wade Wong to provide a complete program of diagnosis and treatment.

    Dr. U's other surgical interests include treatment of brain masses, including meningiomas, astrocytomas, craniopharyngiomas, and pituitary adenomas.

    Dr. U is a renowned expert in brain tumor research. Throughout his research career, he has been entrusted with millions of dollars worth of neurosurgical research grants. He has conducted studies on diseases ranging from human pituitary adenomas to glioblastomas and is pioneering work in gene therapy and brain tissue transplantation.

    Dr. U earned his undergraduate degree from Yale University and his medical degree from Tufts Medical School in Boston, Massachusetts. He completed his residency training at the University of California, San Francisco (UCSF) Medical Center under world-renowned neurosurgeon Dr. Charles B. Wilson. Dr. U has served as the Chief of Neurosurgical Services at the Veterans Administration Medical Center in San Diego since 1983.

    Dr. U has served on numerous scientific and professional committees. Dr. U has been invited as a distinguished lecturer or panelist at over 100 meetings and conferences. He is also a member of numerous scientific and professional societies, including the American Association of Neurological Surgeons, San Diego Academy of Neurological Surgeons, Congress of Neurological Surgeons, and the North American Skull Base Society.

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    NIH/NINDS K07NS000694Jul 1, 1983 - Jun 30, 1988
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Brandel MG, Lee RR, U HS. Transient Aphasia Following Resection of a Thalamic Cavernous Malformation:A Case Report. World Neurosurg. 2020 Jan 28. PMID: 32004743.
      View in: PubMed
    2. Yee B, Chi NW, Hansen LA, Lee RR, U HS, Savides TJ, Vinetz JM. Strongyloides stercoralis Hyperinfection Syndrome Presenting as Severe, Recurrent Gastrointestinal Bleeding, Leading to a Diagnosis of Cushing Disease. Am J Trop Med Hyg. 2015 Oct; 93(4):822-7. PMID: 26195463.
      View in: PubMed
    3. Song Y, Mehta N, Sheh B, Saljooque F, U HS, Rajasekaran M. Transdifferentiation of rat fetal brain stem cells into penile smooth muscle cells. BJU Int. 2009 Jul; 104(2):257-62. PMID: 19220248.
      View in: PubMed
    4. Jandial R, U H, Levy ML, Snyder EY. Brain tumor stem cells and the tumor microenvironmen. Neurosurg Focus. 2008; 24(3-4):E27. PMID: 18341404.
      View in: PubMed
    5. Vorasubin B, Weedin J, Saljooque F, Wilkes N, Eng M, U HS. Selective differentiation of central nervous system-derived stem cells in response to cues from specific regions of the developing brain. J Neurosurg. 2007 Jul; 107(1):145-54. PMID: 17639884.
      View in: PubMed
    6. U HS, Wu B, Wilkes N, Ho A, Saljooque F. Brain stem cells adopt a pituitary fate after implantation into the adult rodent pituitary gland. Neuroendocrinology. 2007; 86(1):58-68. PMID: 17587785.
      View in: PubMed
    7. Park MS, Nguyen AD, Aryan HE, U HS, Levy ML, Semendeferi K. Evolution of the human brain: changing brain size and the fossil record. Neurosurgery. 2007 Mar; 60(3):555-62; discussion 562. PMID: 17327801.
      View in: PubMed
    8. Hölscher T, Rodriguez-Rodriguez J, Wilkening WG, Lasheras JC, U HS. Intraoperative brain ultrasound: a new approach to study flow dynamics in intracranial aneurysms. Ultrasound Med Biol. 2006 Sep; 32(9):1307-13. PMID: 16965970.
      View in: PubMed
    9. Tuszynski MH, U HS, Alksne J, Bakay RA, Pay MM, Merrill D, Thal LJ. Growth factor gene therapy for Alzheimer disease. Neurosurg Focus. 2002 Nov 15; 13(5):e5. PMID: 15769074.
      View in: PubMed
    10. U HS, Alilain W, Saljooque F. Fetal brain progenitor cells transdifferentiate to fates outside the nervous system. Mol Endocrinol. 2002 Nov; 16(11):2645-56. PMID: 12403852.
      View in: PubMed
    11. U HS, Banaie A, Rigby L, Chen J, Meltzer H. Alteration in p53 modulates glial proteins in human glial tumour cells. J Neurooncol. 2000 Jul; 48(3):191-206. PMID: 11100817.
      View in: PubMed