-
Review article: New developments in biomarkers and clinical drug development in alpha-1 antitrypsin deficiency-related liver disease. Aliment Pharmacol Ther. 2024 Mar 22.
Loomba R, Clark G, Teckman J, Ajmera V, Behling C, Brantly M, Brenner D, D'Armiento J, Fried MW, Iyer JS, Mandorfer M, Rockey DC, Tincopa M, Vuppalanchi R, Younossi Z, Krag A, Turner AM, Strnad P. PMID: 38516814.
View in:
PubMed Mentions: Fields:
-
Investigating the Relationship Between Rare Genetic Variants and Fibrosis in Pediatric Nonalcoholic Fatty Liver Disease. medRxiv. 2024 Mar 04.
Wattacheril J, Kleinstein SE, Shea PR, Wilson LA, Subramanian GM, Myers RP, Lefkowitch J, Behling C, Xanthakos SA, Goldstein DB, NASH Clinical Research Network. PMID: 38496563; PMCID: PMC10942529.
View in:
PubMed Mentions:
-
MASH Resolution Index: development and validation of a non-invasive score to detect histological resolution of MASH. Gut. 2024 Feb 28.
Loomba R, Amangurbanova M, Bettencourt R, Madamba E, Siddiqi H, Richards L, Behling C, Sirlin CB, Gottwald MD, Feng S, Margalit M, Huang DQ. PMID: 38418210.
View in:
PubMed Mentions: Fields:
-
A serum-induced gene signature in hepatocytes is associated with pediatric nonalcoholic fatty liver disease. J Pediatr Gastroenterol Nutr. 2024 Feb 23.
Hang Nghiem-Rao T, Johnson JS, Pan A, Atkinson SN, Behling C, Simpson PM, Holtz ML, Weinstock GM, Schwimmer JB, Salzman NH. PMID: 38390691.
View in:
PubMed Mentions: Fields:
-
Artificial intelligence scoring of liver biopsies in a phase II trial of semaglutide in nonalcoholic steatohepatitis. Hepatology. 2023 Dec 19.
Ratziu V, Francque S, Behling CA, Cejvanovic V, Cortez-Pinto H, Iyer JS, Krarup N, Le Q, Sejling AS, Tiniakos D, Harrison SA. PMID: 38112484.
View in:
PubMed Mentions: Fields:
-
Nutrition assessment and MASH severity in children using the Healthy Eating Index. Hepatol Commun. 2023 Dec 01; 7(12).
Jain AK, Buchannan P, Yates KP, Belt P, Schwimmer JB, Rosenthal P, Murray KF, Molleston JP, Scheimann A, Xanthakos SA, Behling CA, Hertel P, Nilson J, Neuschwander-Tetri BA, Tonascia J, Vos MB, Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN). PMID: 38055641; PMCID: PMC10984667.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Liver biopsy for assessment of suspected drug-induced liver injury in metabolic dysfunction-associated steatohepatitis clinical trials: Expert consensus from the Liver Forum. Aliment Pharmacol Ther. 2024 Jan; 59(2):201-216.
Palmer M, Kleiner DE, Goodman Z, Brunt E, Avigan MI, Regev A, Hayashi PH, Lewis JH, Mehta R, Harrison SA, Siciliano M, McWherter CA, Vuppalanchi R, Behling C, Miller V, Chalasani N, Sanyal AJ. PMID: 37877759.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Artificial intelligence-assisted digital pathology for non-alcoholic steatohepatitis: current status and future directions. J Hepatol. 2024 Feb; 80(2):335-351.
Ratziu V, Hompesch M, Petitjean M, Serdjebi C, Iyer JS, Parwani AV, Tai D, Bugianesi E, Cusi K, Friedman SL, Lawitz E, Romero-Gómez M, Schuppan D, Loomba R, Paradis V, Behling C, Sanyal AJ. PMID: 37879461.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Development of Fibro-PeN, a clinical prediction model for moderate-to-severe fibrosis in children with nonalcoholic fatty liver disease. Hepatology. 2023 Oct 23.
Wang A, Blackford AL, Behling C, Wilson LA, Newton KP, Xanthakos SA, Fishbein MH, Vos MB, Mouzaki M, Molleston JP, Jain AK, Hertel P, Harlow Adams K, Schwimmer JB, NASH CRN. PMID: 37870272.
View in:
PubMed Mentions: Fields:
-
Safety and efficacy of once-weekly efruxifermin versus placebo in non-alcoholic steatohepatitis (HARMONY): a multicentre, randomised, double-blind, placebo-controlled, phase 2b trial. Lancet Gastroenterol Hepatol. 2023 Dec; 8(12):1080-1093.
Harrison SA, Frias JP, Neff G, Abrams GA, Lucas KJ, Sanchez W, Gogia S, Sheikh MY, Behling C, Bedossa P, Shao L, Chan D, Fong E, de Temple B, Shringarpure R, Tillman EJ, Rolph T, Cheng A, Yale K, HARMONY Study Group. PMID: 37802088.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansCTClinical Trials
-
Diagnostic performance of circulating biomarkers for non-alcoholic steatohepatitis. Nat Med. 2023 10; 29(10):2656-2664.
Sanyal AJ, Shankar SS, Yates KP, Bolognese J, Daly E, Dehn CA, Neuschwander-Tetri B, Kowdley K, Vuppalanchi R, Behling C, Tonascia J, Samir A, Sirlin C, Sherlock SP, Fowler K, Heymann H, Kamphaus TN, Loomba R, Calle RA. PMID: 37679433; PMCID: PMC10579051.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Clinical and histologic factors associated with discordance between steatosis grade derived from histology vs. MRI-PDFF in NAFLD. Aliment Pharmacol Ther. 2023 07; 58(2):229-237.
Kim BK, Bernstein N, Huang DQ, Tamaki N, Imajo K, Yoneda M, Sutter N, Jung J, Nguyen K, Nguyen L, Le T, Madamba E, Richards L, Valasek MA, Behling C, Sirlin CB, Nakajima A, Loomba R. PMID: 37269117; PMCID: PMC10330628.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Fibrosis Progression Rate in Biopsy-Proven Nonalcoholic Fatty Liver Disease Among People With Diabetes Versus People Without Diabetes: A Multicenter Study. Gastroenterology. 2023 08; 165(2):463-472.e5.
Huang DQ, Wilson LA, Behling C, Kleiner DE, Kowdley KV, Dasarathy S, Amangurbanova M, Terrault NA, Diehl AM, Chalasani N, Neuschwander-Tetri BA, Sanyal AJ, Tonascia J, NASH Clinical Research Network, Loomba R. PMID: 37127100; PMCID: PMC10699569.
View in:
PubMed Mentions:
11 Fields:
Translation:
Humans
-
The nonalcoholic steatohepatitis extended hepatocyte ballooning score: histologic classification and clinical significance. Hepatol Commun. 2023 02 01; 7(2):e0033.
Gill RM, Allende D, Belt PH, Behling CA, Cummings OW, Guy CD, Carpenter D, Neuschwander-Tetri BA, Sanyal AJ, Tonascia J, Van Natta ML, Wilson LA, Yamada G, Yeh M, Kleiner DE, Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN). PMID: 36724127; PMCID: PMC9894357.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansCells
-
The Nimble Stage 1 Study Validates Diagnostic Circulating Biomarkers for Nonalcoholic Steatohepatitis. Res Sq. 2023 Jan 19.
Sanyal A, Shankar S, Yates K, Bolognese J, Daly E, Dehn C, Neuschwander-Tetri B, Kowdley K, Vuppalanchi R, Behling CA, Tonascia J, Samir A, Sirlin C, Sherlock S, Fowler K, Heymann H, Kamphaus T, Loomba R, Calle R. PMID: 36711803; PMCID: PMC9882658.
View in:
PubMed Mentions:
1
-
Defining the serum proteomic signature of hepatic steatosis, inflammation, ballooning and fibrosis in non-alcoholic fatty liver disease. J Hepatol. 2023 04; 78(4):693-703.
Sanyal AJ, Williams SA, Lavine JE, Neuschwander-Tetri BA, Alexander L, Ostroff R, Biegel H, Kowdley KV, Chalasani N, Dasarathy S, Diehl AM, Loomba R, Hameed B, Behling C, Kleiner DE, Karpen SJ, Williams J, Jia Y, Yates KP, Tonascia J. PMID: 36528237; PMCID: PMC10165617.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCTClinical Trials
-
A prospective study on the prevalence of NAFLD, advanced fibrosis, cirrhosis and hepatocellular carcinoma in people with type 2 diabetes. J Hepatol. 2023 03; 78(3):471-478.
Ajmera V, Cepin S, Tesfai K, Hofflich H, Cadman K, Lopez S, Madamba E, Bettencourt R, Richards L, Behling C, Sirlin CB, Loomba R. PMID: 36410554; PMCID: PMC9975077.
View in:
PubMed Mentions:
33 Fields:
Translation:
Humans
-
A randomized, double-blind, placebo-controlled phase IIa trial of efruxifermin for patients with compensated NASH cirrhosis. JHEP Rep. 2023 Jan; 5(1):100563.
Harrison SA, Ruane PJ, Freilich B, Neff G, Patil R, Behling C, Hu C, Shringarpure R, de Temple B, Fong E, Tillman EJ, Rolph T, Cheng A, Yale K. PMID: 36644237; PMCID: PMC9832280.
View in:
PubMed Mentions:
7
-
Head-to-head comparison between MEFIB, MAST, and FAST for detecting stage 2 fibrosis or higher among patients with NAFLD. J Hepatol. 2022 12; 77(6):1482-1490.
Kim BK, Tamaki N, Imajo K, Yoneda M, Sutter N, Jung J, Lin T, Tu XM, Bergstrom J, Nguyen K, Nguyen L, Le T, Madamba E, Richards L, Valasek MA, Behling C, Sirlin CB, Nakajima A, Loomba R. PMID: 35973577.
View in:
PubMed Mentions:
18 Fields:
Translation:
Humans
-
Efficacy and Safety of a Botanical Formula Fuzheng Huayu for Hepatic Fibrosis in Patients with CHC: Results of a Phase 2 Clinical Trial. Evid Based Complement Alternat Med. 2022; 2022:4494099.
Hassanein T, Tai D, Liu C, Box TD, Tong MJ, Rossaro L, Pozza R, Glenn JS, Cheung R, Hemaidan A, He Y, Behling C, Hu X, Makhlouf H, Fan H, Ren Y, Khim Chng EL, Liu P, Vierling JM. PMID: 35873630; PMCID: PMC9307334.
View in:
PubMed Mentions:
2
-
Letter: non-invasive prediction models to exclude cirrhosis in NAFLD-not everyone fits the mould. Authors' reply. Aliment Pharmacol Ther. 2022 07; 56(1):182-183.
Brandman D, Boyle M, McPherson S, Van Natta ML, Sanyal AJ, Kowdley K, Neuschwander-Tetri B, Chalasani N, Abdelmalek MF, Terrault NA, McCullough A, Bettencourt R, Caussy C, Kleiner DE, Behling C, Tonascia J, Anstee QM, Loomba R. PMID: 35689309.
View in:
PubMed Mentions: Fields:
Translation:
HumansAnimals
-
Nonalcoholic fatty liver disease risk and histologic severity are associated with genetic polymorphisms in children. Hepatology. 2023 01 01; 77(1):197-212.
Goyal NP, Rosenthal SB, Nasamran C, Behling CA, Angeles JE, Fishbein MH, Harlow KE, Jain AK, Molleston JP, Newton KP, Ugalde-Nicalo P, Xanthankos SA, Yates K, Schork NJ, Fisch KM, Schwimmer JB, NASH Clinical Research Network. PMID: 35560106; PMCID: PMC9653518.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Incidence of Type 2 Diabetes in Children With Nonalcoholic Fatty Liver Disease. Clin Gastroenterol Hepatol. 2023 05; 21(5):1261-1270.
Newton KP, Wilson LA, Crimmins NA, Fishbein MH, Molleston JP, Xanthakos SA, Behling C, Schwimmer JB, Nonalcoholic Steatohepatitis Clinical Research Network. PMID: 35709934; PMCID: PMC10151072.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Validation of the accuracy of the FAST™ score for detecting patients with at-risk nonalcoholic steatohepatitis (NASH) in a North American cohort and comparison to other non-invasive algorithms. PLoS One. 2022; 17(4):e0266859.
Woreta TA, Van Natta ML, Lazo M, Krishnan A, Neuschwander-Tetri BA, Loomba R, Mae Diehl A, Abdelmalek MF, Chalasani N, Gawrieh S, Dasarathy S, Vuppalanchi R, Siddiqui MS, Kowdley KV, McCullough A, Terrault NA, Behling C, Kleiner DE, Fishbein M, Hertel P, Wilson LA, Mitchell EP, Miriel LA, Clark JM, Tonascia J, Sanyal AJ, NASH Clinical Research Network. PMID: 35427375; PMCID: PMC9012361.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Reliability of histologic assessment for NAFLD and development of an expanded NAFLD activity score. Hepatology. 2022 10; 76(4):1150-1163.
Pai RK, Jairath V, Hogan M, Zou G, Adeyi OA, Anstee QM, Aqel BA, Behling C, Carey EJ, Clouston AD, Corey K, Feagan BG, Kleiner DE, Ma C, McFarlane SC, Noureddin M, Ratziu V, Valasek MA, Younossi ZM, Harrison SA, Loomba R. PMID: 35332569; PMCID: PMC9489601.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Comparison of clinical prediction rules for ruling out cirrhosis in nonalcoholic fatty liver disease (NAFLD). Aliment Pharmacol Ther. 2022 06; 55(11):1441-1451.
Brandman D, Boyle M, McPherson S, Van Natta ML, Sanyal AJ, Kowdley K, Neuschwander-Tetri B, Chalasani N, Abdelmalek MF, Terrault NA, McCullough A, Bettencourt R, Caussy C, Kleiner DE, Behling C, Tonascia J, Anstee QM, Loomba R, Members of the Nonalcoholic Steatohepatitis Clinical Research Network. PMID: 35302256; PMCID: PMC9098681.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Two-Step Strategy, FIB-4 Followed by Magnetic Resonance Elastography, for Detecting Advanced Fibrosis in NAFLD. Clin Gastroenterol Hepatol. 2023 02; 21(2):380-387.e3.
Tamaki N, Imajo K, Sharpton SR, Jung J, Sutter N, Kawamura N, Yoneda M, Valasek MA, Behling C, Sirlin CB, Kurosaki M, Izumi N, Nakajima A, Loomba R. PMID: 35123096.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Magnetic resonance elastography plus Fibrosis-4 versus FibroScan-aspartate aminotransferase in detection of candidates for pharmacological treatment of NASH-related fibrosis. Hepatology. 2022 03; 75(3):661-672.
Tamaki N, Imajo K, Sharpton S, Jung J, Kawamura N, Yoneda M, Valasek MA, Behling C, Sirlin CB, Nakajima A, Loomba R. PMID: 34496054; PMCID: PMC9683538.
View in:
PubMed Mentions:
16 Fields:
Translation:
Humans
-
Prospective Study of Outcomes in Adults with Nonalcoholic Fatty Liver Disease. N Engl J Med. 2021 10 21; 385(17):1559-1569.
Sanyal AJ, Van Natta ML, Clark J, Neuschwander-Tetri BA, Diehl A, Dasarathy S, Loomba R, Chalasani N, Kowdley K, Hameed B, Wilson LA, Yates KP, Belt P, Lazo M, Kleiner DE, Behling C, Tonascia J, NASH Clinical Research Network (CRN). PMID: 34670043; PMCID: PMC8881985.
View in:
PubMed Mentions:
180 Fields:
Translation:
Humans
-
Diagnostic accuracy of two-dimensional shear wave elastography and transient elastography in nonalcoholic fatty liver disease. Therap Adv Gastroenterol. 2021; 14:17562848211050436.
Sharpton SR, Tamaki N, Bettencourt R, Madamba E, Jung J, Liu A, Behling C, Valasek MA, Loomba R. PMID: 34646360; PMCID: PMC8504217.
View in:
PubMed Mentions:
9
-
Efruxifermin in non-alcoholic steatohepatitis: a randomized, double-blind, placebo-controlled, phase 2a trial. Nat Med. 2021 07; 27(7):1262-1271.
Harrison SA, Ruane PJ, Freilich BL, Neff G, Patil R, Behling CA, Hu C, Fong E, de Temple B, Tillman EJ, Rolph TP, Cheng A, Yale K. PMID: 34239138.
View in:
PubMed Mentions:
74 Fields:
Translation:
HumansCTClinical Trials
-
Clinical utility of 30% relative decline in MRI-PDFF in predicting fibrosis regression in non-alcoholic fatty liver disease. Gut. 2022 05; 71(5):983-990.
Tamaki N, Munaganuru N, Jung J, Yonan AQ, Loomba RR, Bettencourt R, Ajmera V, Valasek MA, Behling C, Sirlin CB, Loomba R. PMID: 33883248; PMCID: PMC8594562.
View in:
PubMed Mentions:
23 Fields:
Translation:
Humans
-
Glycogenosis is common in nonalcoholic fatty liver disease and is independently associated with ballooning, but lower steatosis and lower fibrosis. Liver Int. 2021 05; 41(5):996-1011.
Allende DS, Gawrieh S, Cummings OW, Belt P, Wilson L, Van Natta M, Behling CA, Carpenter D, Gill RM, Kleiner DE, Yeh MM, Chalasani N, Guy CD, NASH Clinical Research Network. PMID: 33354866; PMCID: PMC8052274.
View in:
PubMed Mentions:
11 Fields:
Translation:
Humans
-
Alanine Aminotransferase and Gamma-Glutamyl Transpeptidase Predict Histologic Improvement in Pediatric Nonalcoholic Steatohepatitis. Hepatology. 2021 03; 73(3):937-951.
Newton KP, Lavine JE, Wilson L, Behling C, Vos MB, Molleston JP, Rosenthal P, Miloh T, Fishbein MH, Jain AK, Murray KF, Schwimmer JB, Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN). PMID: 32416645; PMCID: PMC7669708.
View in:
PubMed Mentions:
19 Fields:
Translation:
Humans
-
MRE combined with FIB-4 (MEFIB) index in detection of candidates for pharmacological treatment of NASH-related fibrosis. Gut. 2021 10; 70(10):1946-1953.
Jung J, Loomba RR, Imajo K, Madamba E, Gandhi S, Bettencourt R, Singh S, Hernandez C, Valasek MA, Behling C, Richards L, Fowler K, Sirlin CB, Nakajima A, Loomba R. PMID: 33214165; PMCID: PMC8131405.
View in:
PubMed Mentions:
42 Fields:
Translation:
Humans
-
Clinical Utility of Change in Nonalcoholic Fatty Liver Disease Activity Score and Change in Fibrosis in NAFLD. Clin Gastroenterol Hepatol. 2021 12; 19(12):2673-2674.e3.
Tamaki N, Munaganuru N, Jung J, Yonan AQ, Bettencourt R, Ajmera V, Valasek MA, Behling C, Loomba R. PMID: 33157318; PMCID: PMC8438785.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Sex Hormone Relations to Histologic Severity of Pediatric Nonalcoholic Fatty Liver Disease. J Clin Endocrinol Metab. 2020 11 01; 105(11).
Mueller NT, Liu T, Mitchel EB, Yates KP, Suzuki A, Behling C, Lavine JE. PMID: 32840311; PMCID: PMC7494240.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Multicenter Validation of Association Between Decline in MRI-PDFF and Histologic Response in NASH. Hepatology. 2020 10; 72(4):1219-1229.
Loomba R, Neuschwander-Tetri BA, Sanyal A, Chalasani N, Diehl AM, Terrault N, Kowdley K, Dasarathy S, Kleiner D, Behling C, Lavine J, Van Natta M, Middleton M, Tonascia J, Sirlin C, NASH Clinical Research Network. PMID: 31965579; PMCID: PMC8055244.
View in:
PubMed Mentions:
42 Fields:
Translation:
HumansCTClinical Trials
-
Digital Whole Slide Imaging Compared With Light Microscopy for Primary Diagnosis in Surgical Pathology. Arch Pathol Lab Med. 2020 10 01; 144(10):1245-1253.
Borowsky AD, Glassy EF, Wallace WD, Kallichanda NS, Behling CA, Miller DV, Oswal HN, Feddersen RM, Bakhtar OR, Mendoza AE, Molden DP, Saffer HL, Wixom CR, Albro JE, Cessna MH, Hall BJ, Lloyd IE, Bishop JW, Darrow MA, Gui D, Jen KY, Walby JAS, Bauer SM, Cortez DA, Gandhi P, Rodgers MM, Rodriguez RA, Martin DR, McConnell TG, Reynolds SJ, Spigel JH, Stepenaskie SA, Viktorova E, Magari R, Wharton KA, Qiu J, Bauer TW. PMID: 32057275.
View in:
PubMed Mentions:
33 Fields:
Translation:
Humans
-
Progression of Fatty Liver Disease in Children Receiving Standard of Care Lifestyle Advice. Gastroenterology. 2020 11; 159(5):1731-1751.e10.
Xanthakos SA, Lavine JE, Yates KP, Schwimmer JB, Molleston JP, Rosenthal P, Murray KF, Vos MB, Jain AK, Scheimann AO, Miloh T, Fishbein M, Behling CA, Brunt EM, Sanyal AJ, Tonascia J, NASH Clinical Research Network. PMID: 32712103; PMCID: PMC7680281.
View in:
PubMed Mentions:
23 Fields:
Translation:
Humans
-
Precise Identification of Cell and Tissue Features Important for Histopathologic Diagnosis by a Whole Slide Imaging System. J Pathol Inform. 2020; 11:3.
Bauer TW, Behling C, Miller DV, Chang BS, Viktorova E, Magari R, Jensen PE, Wharton KA, Qiu J. PMID: 32154040; PMCID: PMC7032023.
View in:
PubMed Mentions:
4
-
Clinical Utility of an Increase in Magnetic Resonance Elastography in Predicting Fibrosis Progression in Nonalcoholic Fatty Liver Disease. Hepatology. 2020 03; 71(3):849-860.
Ajmera VH, Liu A, Singh S, Yachoa G, Ramey M, Bhargava M, Zamani A, Lopez S, Mangla N, Bettencourt R, Rizo E, Valasek M, Behling C, Richards L, Sirlin C, Loomba R. PMID: 31556124; PMCID: PMC7828573.
View in:
PubMed Mentions:
40 Fields:
Translation:
Humans
-
Haptoglobin 2 Allele is Associated With Histologic Response to Vitamin E in Subjects With Nonalcoholic Steatohepatitis. J Clin Gastroenterol. 2019 Nov/Dec; 53(10):750-758.
Banini BA, Cazanave SC, Yates KP, Asgharpour A, Vincent R, Mirshahi F, Le P, Contos MJ, Tonascia J, Chalasani NP, Kowdley KV, McCullough AJ, Behling CA, Schwimmer JB, Lavine JE, Sanyal AJ, Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN). PMID: 30586008; PMCID: PMC6588507.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Standardising the interpretation of liver biopsies in non-alcoholic fatty liver disease clinical trials. Aliment Pharmacol Ther. 2019 11; 50(10):1100-1111.
Pai RK, Kleiner DE, Hart J, Adeyi OA, Clouston AD, Behling CA, Jain D, Kakar S, Brahmania M, Burgart L, Batts KP, Valasek MA, Torbenson MS, Guindi M, Wang HL, Ajmera V, Adams LA, Parker CE, Feagan BG, Loomba R, Jairath V. PMID: 31583739; PMCID: PMC6817398.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Association of Histologic Disease Activity With Progression of Nonalcoholic Fatty Liver Disease. JAMA Netw Open. 2019 10 02; 2(10):e1912565.
Kleiner DE, Brunt EM, Wilson LA, Behling C, Guy C, Contos M, Cummings O, Yeh M, Gill R, Chalasani N, Neuschwander-Tetri BA, Diehl AM, Dasarathy S, Terrault N, Kowdley K, Loomba R, Belt P, Tonascia J, Lavine JE, Sanyal AJ, Nonalcoholic Steatohepatitis Clinical Research Network. PMID: 31584681; PMCID: PMC6784786.
View in:
PubMed Mentions:
102 Fields:
Translation:
Humans
-
Microbiome Signatures Associated With Steatohepatitis and Moderate to Severe Fibrosis in Children With Nonalcoholic Fatty Liver Disease. Gastroenterology. 2019 10; 157(4):1109-1122.
Schwimmer JB, Johnson JS, Angeles JE, Behling C, Belt PH, Borecki I, Bross C, Durelle J, Goyal NP, Hamilton G, Holtz ML, Lavine JE, Mitreva M, Newton KP, Pan A, Simpson PM, Sirlin CB, Sodergren E, Tyagi R, Yates KP, Weinstock GM, Salzman NH. PMID: 31255652; PMCID: PMC6756995.
View in:
PubMed Mentions:
96 Fields:
Translation:
HumansCells
-
Hepatic R2* is more strongly associated with proton density fat fraction than histologic liver iron scores in patients with nonalcoholic fatty liver disease. J Magn Reson Imaging. 2019 05; 49(5):1456-1466.
Bashir MR, Wolfson T, Gamst AC, Fowler KJ, Ohliger M, Shah SN, Alazraki A, Trout AT, Behling C, Allende DS, Loomba R, Sanyal A, Schwimmer J, Lavine JE, Shen W, Tonascia J, Van Natta ML, Mamidipalli A, Hooker J, Kowdley KV, Middleton MS, Sirlin CB, NASH Clinical Research Network (NASH CRN). PMID: 30318834; PMCID: PMC6449180.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
-
Exome sequencing of an adolescent with nonalcoholic fatty liver disease identifies a clinically actionable case of Wilson disease. Cold Spring Harb Mol Case Stud. 2018 10; 4(5).
Wattacheril J, Shea PR, Mohammad S, Behling C, Aggarwal V, Wilson LA, Yates KP, Ito J, Fishbein M, Stong N, Lavine JE, Goldstein DB. PMID: 30026388; PMCID: PMC6169823.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Hepatic Nuclear Receptor Expression Associates with Features of Histology in Pediatric Nonalcoholic Fatty Liver Disease. Hepatol Commun. 2018 Oct; 2(10):1213-1226.
Elbel EE, Lavine JE, Downes M, Van Natta M, Yu R, Schwimmer JB, Behling C, Brunt EM, Tonascia J, Evans R. PMID: 30288476; PMCID: PMC6167075.
View in:
PubMed Mentions:
10 Fields:
-
Magnetic Resonance Imaging Proton Density Fat Fraction Associates With Progression of Fibrosis in Patients With Nonalcoholic Fatty Liver Disease. Gastroenterology. 2018 08; 155(2):307-310.e2.
Ajmera V, Park CC, Caussy C, Singh S, Hernandez C, Bettencourt R, Hooker J, Sy E, Behling C, Xu R, Middleton MS, Valasek MA, Faulkner C, Rizo E, Richards L, Sirlin CB, Loomba R. PMID: 29660324; PMCID: PMC6090543.
View in:
PubMed Mentions:
63 Fields:
Translation:
Humans
-
Clinically Actionable Hypercholesterolemia and Hypertriglyceridemia in Children with Nonalcoholic Fatty Liver Disease. J Pediatr. 2018 07; 198:76-83.e2.
Harlow KE, Africa JA, Wells A, Belt PH, Behling CA, Jain AK, Molleston JP, Newton KP, Rosenthal P, Vos MB, Xanthakos SA, Lavine JE, Schwimmer JB, Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN). PMID: 29661561; PMCID: PMC6019181.
View in:
PubMed Mentions:
14 Fields:
Translation:
Humans
-
Magnetic resonance elastography measured shear stiffness as a biomarker of fibrosis in pediatric nonalcoholic fatty liver disease. Hepatology. 2017 11; 66(5):1474-1485.
Schwimmer JB, Behling C, Angeles JE, Paiz M, Durelle J, Africa J, Newton KP, Brunt EM, Lavine JE, Abrams SH, Masand P, Krishnamurthy R, Wong K, Ehman RL, Yin M, Glaser KJ, Dzyubak B, Wolfson T, Gamst AC, Hooker J, Haufe W, Schlein A, Hamilton G, Middleton MS, Sirlin CB. PMID: 28493388; PMCID: PMC5650504.
View in:
PubMed Mentions:
45 Fields:
Translation:
Humans
-
Low and High Birth Weights Are Risk Factors for Nonalcoholic Fatty Liver Disease in Children. J Pediatr. 2017 08; 187:141-146.e1.
Newton KP, Feldman HS, Chambers CD, Wilson L, Behling C, Clark JM, Molleston JP, Chalasani N, Sanyal AJ, Fishbein MH, Lavine JE, Schwimmer JB, Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN). PMID: 28366357; PMCID: PMC5533631.
View in:
PubMed Mentions:
49 Fields:
Translation:
Humans
-
In Children With Nonalcoholic Fatty Liver Disease, Zone 1 Steatosis Is Associated With Advanced Fibrosis. Clin Gastroenterol Hepatol. 2018 03; 16(3):438-446.e1.
Africa JA, Behling CA, Brunt EM, Zhang N, Luo Y, Wells A, Hou J, Belt PH, Kohil R, Lavine JE, Molleston JP, Newton KP, Whitington PF, Schwimmer JB, Nonalcoholic Steatohepatitis Clinical Research Network. PMID: 28286193; PMCID: PMC5589478.
View in:
PubMed Mentions:
25 Fields:
Translation:
Humans
-
Liver histology and diffusion-weighted MRI in children with nonalcoholic fatty liver disease: A MAGNET study. J Magn Reson Imaging. 2017 10; 46(4):1149-1158.
Manning P, Murphy P, Wang K, Hooker J, Wolfson T, Middleton MS, Newton KP, Behling C, Awai HI, Durelle J, Paiz MN, Angeles JE, De La Pena D, McCutchan JA, Schwimmer JB, Sirlin CB. PMID: 28225568; PMCID: PMC5568908.
View in:
PubMed Mentions:
15 Fields:
Translation:
Humans
-
Prevalence of Prediabetes and Type 2 Diabetes in Children With Nonalcoholic Fatty Liver Disease. JAMA Pediatr. 2016 Oct 03; 170(10):e161971.
Newton KP, Hou J, Crimmins NA, Lavine JE, Barlow SE, Xanthakos SA, Africa J, Behling C, Donithan M, Clark JM, Schwimmer JB, Nonalcoholic Steatohepatitis Clinical Research Network. PMID: 27478956; PMCID: PMC5479314.
View in:
PubMed Mentions:
102 Fields:
Translation:
Humans
-
Staging of fibrosis in experimental non-alcoholic steatohepatitis by quantitative molecular imaging in rat models. Nucl Med Biol. 2016 Feb; 43(2):179-87.
Schnabl B, Farshchi-Heydari S, Loomba R, Mattrey RF, Hoh CK, Sirlin CB, Brenner DA, Behling CA, Vera DR. PMID: 26872443.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimals
-
Magnetic resonance imaging and liver histology as biomarkers of hepatic steatosis in children with nonalcoholic fatty liver disease. Hepatology. 2015 Jun; 61(6):1887-95.
Schwimmer JB, Middleton MS, Behling C, Newton KP, Awai HI, Paiz MN, Lam J, Hooker JC, Hamilton G, Fontanesi J, Sirlin CB. PMID: 25529941; PMCID: PMC4670559.
View in:
PubMed Mentions:
82 Fields:
Translation:
HumansCTClinical Trials
-
Association Between Quantity of Liver Fat and Cardiovascular Risk in Patients With Nonalcoholic Fatty Liver Disease Independent of Nonalcoholic Steatohepatitis. Clin Gastroenterol Hepatol. 2015 Aug; 13(8):1513-20.e1.
Arulanandan A, Ang B, Bettencourt R, Hooker J, Behling C, Lin GY, Valasek MA, Ix JH, Schnabl B, Sirlin CB, Loomba R. PMID: 25661453.
View in:
PubMed Mentions:
51 Fields:
Translation:
Humans
-
Longitudinal assessment of high blood pressure in children with nonalcoholic fatty liver disease. PLoS One. 2014; 9(11):e112569.
Schwimmer JB, Zepeda A, Newton KP, Xanthakos SA, Behling C, Hallinan EK, Donithan M, Tonascia J, Nonalcoholic Steatohepatitis Clinical Research Network. PMID: 25419656; PMCID: PMC4242611.
View in:
PubMed Mentions:
46 Fields:
Translation:
Humans
-
Reproducibility of histological assessments of disease activity in UC. Gut. 2015 Nov; 64(11):1765-73.
Mosli MH, Feagan BG, Zou G, Sandborn WJ, D'Haens G, Khanna R, Behling C, Kaplan K, Driman DK, Shackelton LM, Baker KA, MacDonald JK, Vandervoort MK, Samaan MA, Geboes K, Valasek MA, Pai R, Langner C, Riddell R, Harpaz N, Sewitch M, Peterson M, Stitt LW, Levesque BG. PMID: 25360036.
View in:
PubMed Mentions:
24 Fields:
Translation:
Humans
-
Magnetic resonance elastography predicts advanced fibrosis in patients with nonalcoholic fatty liver disease: a prospective study. Hepatology. 2014 Dec; 60(6):1920-8.
Loomba R, Wolfson T, Ang B, Hooker J, Behling C, Peterson M, Valasek M, Lin G, Brenner D, Gamst A, Ehman R, Sirlin C. PMID: 25103310; PMCID: PMC4245360.
View in:
PubMed Mentions:
200 Fields:
Translation:
HumansCTClinical Trials
-
Associations between histologic features of nonalcoholic fatty liver disease (NAFLD) and quantitative diffusion-weighted MRI measurements in adults. J Magn Reson Imaging. 2015 Jun; 41(6):1629-38.
Murphy P, Hooker J, Ang B, Wolfson T, Gamst A, Bydder M, Middleton M, Peterson M, Behling C, Loomba R, Sirlin C. PMID: 25256692; PMCID: PMC4819971.
View in:
PubMed Mentions:
28 Fields:
Translation:
Humans
-
Histologic evaluation of ulcerative colitis: a systematic review of disease activity indices. Inflamm Bowel Dis. 2014 Mar; 20(3):564-75.
Mosli MH, Feagan BG, Sandborn WJ, D'haens G, Behling C, Kaplan K, Driman DK, Shackelton LM, Baker KA, Macdonald JK, Vandervoort MK, Geboes K, Levesque BG. PMID: 24412993.
View in:
PubMed Mentions:
34 Fields:
Translation:
Humans
-
Clinical and histological determinants of nonalcoholic steatohepatitis and advanced fibrosis in elderly patients. Hepatology. 2013 Nov; 58(5):1644-54.
Noureddin M, Yates KP, Vaughn IA, Neuschwander-Tetri BA, Sanyal AJ, McCullough A, Merriman R, Hameed B, Doo E, Kleiner DE, Behling C, Loomba R, NASH CRN. PMID: 23686698; PMCID: PMC3760979.
View in:
PubMed Mentions:
66 Fields:
Translation:
Humans
-
Evidence and recommendations for imaging liver fat in children, based on systematic review. Clin Gastroenterol Hepatol. 2014 May; 12(5):765-73.
Awai HI, Newton KP, Sirlin CB, Behling C, Schwimmer JB. PMID: 24090729; PMCID: PMC3969892.
View in:
PubMed Mentions:
49 Fields:
Translation:
Humans
-
Misuse of scoring systems. Hepatology. 2011 Jul; 54(1):369-70; author reply 370-1.
Brunt EM, Kleiner DE, Behling C, Contos MJ, Cummings OW, Ferrell LD, Torbenson MS, Yeh M. PMID: 21488072.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCells
-
Association between metabolic syndrome and liver histology among children with nonalcoholic Fatty liver disease. Am J Gastroenterol. 2010 Sep; 105(9):2093-102.
Patton HM, Yates K, Unalp-Arida A, Behling CA, Huang TT, Rosenthal P, Sanyal AJ, Schwimmer JB, Lavine JE. PMID: 20372110; PMCID: PMC3070291.
View in:
PubMed Mentions:
55 Fields:
Translation:
Humans
-
Impact of abdominal helical computed tomography on the rate of negative appendicitis. J Emerg Med. 2008 Jan; 34(1):7-11.
Guss DA, Behling CA, Munassi D. PMID: 18155380.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
EUS-guided FNA diagnostic yield of malignancy in solid pancreatic masses: a benchmark for quality performance measurement. Gastrointest Endosc. 2007 Aug; 66(2):277-82.
Savides TJ, Donohue M, Hunt G, Al-Haddad M, Aslanian H, Ben-Menachem T, Chen VK, Coyle W, Deutsch J, DeWitt J, Dhawan M, Eckardt A, Eloubeidi M, Esker A, Gordon SR, Gress F, Ikenberry S, Joyce AM, Klapman J, Lo S, Maluf-Filho F, Nickl N, Singh V, Wills J, Behling C. PMID: 17643700.
View in:
PubMed Mentions:
57 Fields:
Translation:
Humans
-
Age and time as factors in the left-to-right shift of the subsite of colorectal adenocarcinoma: a study of 213,383 cases from the California Cancer Registry. J Clin Gastroenterol. 2007 Feb; 41(2):173-7.
Saltzstein SL, Behling CA. PMID: 17245216.
View in:
PubMed Mentions:
42 Fields:
Translation:
Humans
-
Prevalence of fatty liver in children and adolescents. Pediatrics. 2006 Oct; 118(4):1388-93.
Schwimmer JB, Deutsch R, Kahen T, Lavine JE, Stanley C, Behling C. PMID: 17015527.
View in:
PubMed Mentions:
542 Fields:
Translation:
Humans
-
Pediatric nonalcoholic fatty liver disease: a critical appraisal of current data and implications for future research. J Pediatr Gastroenterol Nutr. 2006 Oct; 43(4):413-27.
Patton HM, Sirlin C, Behling C, Middleton M, Schwimmer JB, Lavine JE. PMID: 17033514.
View in:
PubMed Mentions:
68 Fields:
Translation:
HumansPHPublic Health
-
Liver fibrosis: noninvasive diagnosis with double contrast material-enhanced MR imaging. Radiology. 2006 May; 239(2):425-37.
Aguirre DA, Behling CA, Alpert E, Hassanein TI, Sirlin CB. PMID: 16641352.
View in:
PubMed Mentions:
62 Fields:
Translation:
Humans
-
Severe upper-GI bleed caused by gastritis cystica profunda. Gastrointest Endosc. 2006 Apr; 63(4):716-7.
Kurland J, DuBois S, Behling C, Savides T. PMID: 16564886.
View in:
PubMed Mentions:
12 Fields:
Translation:
Humans
-
Impact of helical computed tomography on the rate of negative appendicitis. Am J Emerg Med. 2006 Jan; 24(1):43-7.
Vadeboncoeur TF, Heister RR, Behling CA, Guss DA. PMID: 16338508.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Histopathology of pediatric nonalcoholic fatty liver disease. Hepatology. 2005 Sep; 42(3):641-9.
Schwimmer JB, Behling C, Newbury R, Deutsch R, Nievergelt C, Schork NJ, Lavine JE. PMID: 16116629.
View in:
PubMed Mentions:
251 Fields:
Translation:
Humans
-
Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology. 2005 Jun; 41(6):1313-21.
Kleiner DE, Brunt EM, Van Natta M, Behling C, Contos MJ, Cummings OW, Ferrell LD, Liu YC, Torbenson MS, Unalp-Arida A, Yeh M, McCullough AJ, Sanyal AJ, Nonalcoholic Steatohepatitis Clinical Research Network. PMID: 15915461.
View in:
PubMed Mentions:
3840 Fields:
Translation:
Humans
-
Utility of immediate evaluation of endoscopic ultrasound-guided transesophageal fine needle aspiration of mediastinal lymph nodes. Acta Cytol. 2004 Sep-Oct; 48(5):630-4.
Emery SC, Savides TJ, Behling CA. PMID: 15471254.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Cytomegalovirus ischemic colitis: a near-fatal presentation of HIV infection. AIDS Patient Care STDS. 2004 Sep; 18(9):497-500.
Lin RK, Behling CA, Garvie JJ. PMID: 15630769.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
The impact of steatosis on disease progression and early and sustained treatment response in chronic hepatitis C patients. J Hepatol. 2004 Mar; 40(3):484-90.
Patton HM, Patel K, Behling C, Bylund D, Blatt LM, Vallée M, Heaton S, Conrad A, Pockros PJ, McHutchison JG. PMID: 15123364.
View in:
PubMed Mentions:
87 Fields:
Translation:
HumansCells
-
Use of 5-fluorouracil and survival in patients with microsatellite-unstable colorectal cancer. Gastroenterology. 2004 Feb; 126(2):394-401.
Carethers JM, Smith EJ, Behling CA, Nguyen L, Tajima A, Doctolero RT, Cabrera BL, Goel A, Arnold CA, Miyai K, Boland CR. PMID: 14762775.
View in:
PubMed Mentions:
191 Fields:
Translation:
HumansCells
-
Obesity, insulin resistance, and other clinicopathological correlates of pediatric nonalcoholic fatty liver disease. J Pediatr. 2003 Oct; 143(4):500-5.
Schwimmer JB, Deutsch R, Rauch JB, Behling C, Newbury R, Lavine JE. PMID: 14571229.
View in:
PubMed Mentions:
137 Fields:
Translation:
Humans
-
Increased expression of endoarterial vascular cell adhesion molecule-1 mRNA in an experimental model of lung transplant rejection: diagnosis by pulmonary arterial biopsy. Transplantation. 2003 Apr 15; 75(7):960-5.
Rothman A, Mann D, Behling CA, McGraw M, Seslar S, Shiu P, Zhang L, Kriett JM. PMID: 12698080.
View in:
PubMed Mentions:
7 Fields:
Translation:
Animals
-
Clinical use of hyaluronic acid as a predictor of fibrosis change in hepatitis C. J Gastroenterol Hepatol. 2003 Mar; 18(3):253-7.
Patel K, Lajoie A, Heaton S, Pianko S, Behling CA, Bylund D, Pockros PJ, Blatt LM, Conrad A, McHutchison JG. PMID: 12603524.
View in:
PubMed Mentions:
21 Fields:
Translation:
Humans
-
Balloon angioplasty and stenting of multiple intralobar pulmonary arterial stenoses in adult patients. Catheter Cardiovasc Interv. 2003 Feb; 58(2):252-60.
Rothman A, Levy DJ, Sklansky MS, Grossfeld PD, Auger WR, Ajami GH, Behling CA. PMID: 12552552.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Parathyroid hormone-related protein as a novel tumor marker in pancreatic adenocarcinoma. Pancreas. 2002 Apr; 24(3):284-90.
Bouvet M, Nardin SR, Burton DW, Lee NC, Yang M, Wang X, Baranov E, Behling C, Moossa AR, Hoffman RM, Deftos LJ. PMID: 11893937.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
-
Main portal vein access in transjugular intrahepatic portosystemic shunt procedures: use of three-dimensional ultrasound to ensure safety. J Vasc Interv Radiol. 2002 Mar; 13(3):267-73.
Rose SC, Behling C, Roberts AC, Pretorius DH, Nelson TR, Kinney TB, Masliah E, Hassanein TI. PMID: 11875086.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans