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Thomas O'keefe

Title(s)Assistant Professor Of Clinical, Surgery
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Problematic Media Usage Patterns in Adolescents. JAMA. 2025 Nov 11; 334(18):1678. Choi SH, O'Keefe TJ. PMID: 41051744.
      View in: PubMed   Mentions:    Fields:    
    2. Rethinking the Unplanned ICU Admission Quality Metric in Trauma Patients. Am Surg. 2026 Apr; 92(4):1251-1258. Mou Z, Oviedo P, Perkins L, Costantini TW, O'Keefe T, Horita HM, Doucet JJ, Haines LN, Santorelli JE. PMID: 41165071.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. A Nomenclature for Surgical Knots and the Principles of Knot Security. Am Surg. 2025 Nov; 91(11):2000-2006. O'Keefe TJ, Cosman BC, Perkins LA, Guajardo I, Adams LM, Ardill WD, Potenza BM. PMID: 40608797.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Using half-hitch knots to uncouple surgical knot security and loop tautness. Ann Transl Med. 2025 Apr 30; 13(2):15. O'Keefe TJ, Perkins LA, Guajardo I, Adams LM, Cosman BC, Ardill WD, Potenza BM. PMID: 40438513; PMCID: PMC12106118.
      View in: PubMed   Mentions:
    5. Using Millimeter Measurements and Force Gauges to Test the Security of Knots Tied by Residents Before and After Watching Online Didactic Videos. Am Surg. 2025 Sep; 91(9):1511-1517. O'Keefe TJ, Perkins LA, Austin J, Oviedo P, Khan S, Guajardo I, Adams LM, Cosman BC, Ardill WD, Potenza BM. PMID: 40280114.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Bilateral Mastectomy vs Lumpectomy and Breast Cancer Mortality Risk. JAMA Oncol. 2025 Feb 01; 11(2):185. O'Keefe TJ, Alvarado MD, Esserman LJ. PMID: 39666317.
      View in: PubMed   Mentions:    Fields:    
    7. "The Gordian knot of it he will unloose": Lessons learned from studies of half-hitch surgical knots and implications for practicing surgeons: A systematic review. Surgery. 2025 02; 178:108932. O'Keefe TJ, Lake C, Perkins LA, Perez SA, Guajardo I, Carlson Hyman S, Adams LM, Cosman BC, Ardill WD, Potenza BM. PMID: 39592332.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Modernizing Surgical Quality: A Novel Approach to Improving Detection of Surgical Site Infections in the Veteran Population. Surg Infect (Larchmt). 2024 Sep; 25(7):499-504. Perkins L, O'Keefe T, Ardill W, Potenza B. PMID: 38973692.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Reply to: "Is Choosing Wisely Wise for Lobular Carcinoma in Patients Over 70 Years of Age? A National Cancer Database Analysis of Sentinel Node Practice Patterns. Ann Surg Oncol. 2024 03; 31(3):1669-1670. Goldhaber N, O'Keefe T, Blair S. PMID: 38017123.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    10. Glucocorticoid receptor regulates the epithelial-mesenchymal transition process through GR/ZEB1/E-cad and is involved in breast cancer endocrine drug resistance-a bioinformatics analysis. Transl Cancer Res. 2023 Nov 30; 12(11):3129-3146. Tang Y, Ma J, Zhang H, Ma W, Ma W, O'Keefe TJ, Pratap A, Yamada A, Wang L, Gao Y, Zhang Q, Zhao W. PMID: 38130302; PMCID: PMC10731348.
      View in: PubMed   Mentions: 2  
    11. ASO Visual Abstract: Is Choosing Wisely Wise for Lobular Carcinoma in Patients Over 70? A National Cancer Database (NCDB) Analysis of Sentinel Node Practice Patterns. Ann Surg Oncol. 2023 Oct; 30(10):6033. Goldhaber NH, O'Keefe T, Kang J, Douglas S, Blair SL. PMID: 37626253.
      View in: PubMed   Mentions:    Fields:    
    12. Is Choosing Wisely Wise for Lobular Carcinoma in Patients Over 70 Years of Age? A National Cancer Database Analysis of Sentinel Node Practice Patterns. Ann Surg Oncol. 2023 Oct; 30(10):6024-6032. Goldhaber NH, O'Keefe T, Kang J, Douglas S, Blair SL. PMID: 37490163; PMCID: PMC10495516.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    13. Prognostic Significance of Residual Ductal Carcinoma In Situ After Complete Response of Invasive Breast Cancer to Neoadjuvant Therapy. JAMA Surg. 2023 06 01; 158(6):674-675. O'Keefe TJ, Wallace AM. PMID: 36811893.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    14. Bilateral mastectomy associated with higher breast cancer mortality among patients with estrogen receptor positive progesterone receptor negative localized breast cancer. Chin Clin Oncol. 2023 Feb; 12(1):3. O'Keefe TJ, Harismendy O, Wallace AM. PMID: 36922359.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. Accurate genome-wide genotyping from archival tissue to explore the contribution of common genetic variants to pre-cancer outcomes. J Transl Med. 2022 12 27; 20(1):623. Nachmanson D, Pagadala M, Steward J, Cheung C, Bruce LK, Lee NQ, O'Keefe TJ, Lin GY, Hasteh F, Morris GP, Carter H, Harismendy O. PMID: 36575447; PMCID: PMC9793518.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    16. Efficacy and safety of neoadjuvant pertuzumab plus trastuzumab in combination with chemotherapy regimen in Chinese patients with HER2-positive early breast cancer: a real-world retrospective multi-center cohort study. Ann Transl Med. 2022 Dec; 10(24):1387. Zhou M, Wang S, Wan N, Yuan S, Hu X, Zhou W, Qing B, Liu M, Sun W, Fan P, Wang J, Cao H, Xu H, Dai B, Tang P, Qian L, Zhao X, Xiao J, Zhou H, Hu J, Ding L, Tripodi D, Zdenkowski N, O'Keefe TJ, Sanchez AM, Chen L, Zhang P, Xu F. PMID: 36660637; PMCID: PMC9843401.
      View in: PubMed   Mentions: 9  
    17. Risk factors for breast cancer mortality after ductal carcinoma in situ diagnosis differ from those for invasive recurrence. Surgery. 2023 02; 173(2):305-311. O'Keefe TJ, Chau H, Harismendy O, Wallace AM. PMID: 36435650.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    18. Histopathological growth distribution of ductal carcinoma in situ: tumor size is not "one size fits all". Gland Surg. 2022 Feb; 11(2):307-318. O'Keefe TJ, Harismendy O, Wallace AM. PMID: 35284308; PMCID: PMC8899433.
      View in: PubMed   Mentions: 3  
    19. The breast pre-cancer atlas illustrates the molecular and micro-environmental diversity of ductal carcinoma in situ. NPJ Breast Cancer. 2022 Jan 13; 8(1):6. Nachmanson D, Officer A, Mori H, Gordon J, Evans MF, Steward J, Yao H, O'Keefe T, Hasteh F, Stein GS, Jepsen K, Weaver DL, Hirst GL, Sprague BL, Esserman LJ, Borowsky AD, Stein JL, Harismendy O. PMID: 35027560; PMCID: PMC8758681.
      View in: PubMed   Mentions: 12  
    20. Large and diffuse ductal carcinoma in situ: potentially lethal subtypes of "preinvasive" disease. Int J Clin Oncol. 2022 Jan; 27(1):121-130. O'Keefe TJ, Harismendy O, Wallace AM. PMID: 34618239; PMCID: PMC10874643.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    21. Archives of Breast Cancer. Personalization of Ductal Carcinoma In-Situ Management: Large Databases and an Emerging Role for Global Data Sharing. 2021; 8(1). O'keefe TJ, Harismendy O, Esserman L, Wallace AM.
    22. Mutational profiling of micro-dissected pre-malignant lesions from archived specimens. BMC Med Genomics. 2020 11 18; 13(1):173. Nachmanson D, Steward J, Yao H, Officer A, Jeong E, O'Keefe TJ, Hasteh F, Jepsen K, Hirst GL, Esserman LJ, Borowsky AD, Harismendy O. PMID: 33208147; PMCID: PMC7672910.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    23. Ductal carcinoma in situ in patients younger than 30 years: differences in adjuvant endocrine therapy and outcomes. Breast Cancer Res Treat. 2021 Apr; 186(2):551-559. Halasz SR, O'Keefe T, Wallace AM, Blair SL. PMID: 33180236; PMCID: PMC7994183.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    24. Surveillance, Epidemiology, and End Results program underestimates breast cancer-specific mortality after ductal carcinoma in situ diagnosis. Breast Cancer Res Treat. 2020 08; 182(3):761-762. O'Keefe TJ, Wallace AM. PMID: 32529407.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    25. HER2-Overexpressing Ductal Carcinoma In Situ Associated with Increased Risk of Ipsilateral Invasive Recurrence, Receptor Discordance with Recurrence. Cancer Prev Res (Phila). 2020 09; 13(9):761-772. O'Keefe TJ, Blair SL, Hosseini A, Harismendy O, Wallace AM. PMID: 32493703; PMCID: PMC7483601.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    26. Characterization of the seismic environment at the Sanford Underground Laboratory, South Dakota. Classical and Quantum Gravity. 2010; 22(27). Harms J, Acernese F, Barone F, Bartos I, Beker M, Brand JFJ, Christensen N, Coughlin M, DeSalvo R, Dorsher S, Heise J, Kandhasamy S, Mandic V, Marka S, Muller G, Naticchioni L, O'keefe TJ, Rabeling DS, Sajeva A, Trancynger T, Wand V.
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