Loading...
Sign in to edit your profile (add interests, mentoring, photo, etc.)

    Alexis Komor

    TitleAssistant Researcher
    SchoolUniversity of California, San Diego
    DepartmentChemistry and Biochemistry
    Address9500 Gilman Drive #0332
    CA La Jolla 92093
    Phone858-246-2608
    vCardDownload vCard

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Komor A, Badran AH, Liu DR. Editing the Genome Without Double-Stranded DNA Breaks. ACS Chem Biol. 2017 Sep 28. PMID: 28957631.
        View in: PubMed
      2. Komor A, Zhao KT, Packer MS, Gaudelli NM, Waterbury AL, Koblan LW, Kim YB, Badran AH, Liu DR. Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity. Sci Adv. 2017 Aug; 3(8):eaao4774. PMID: 28875174.
        View in: PubMed
      3. Rees HA, Komor A, Yeh WH, Caetano-Lopes J, Warman M, Edge ASB, Liu DR. Improving the DNA specificity and applicability of base editing through protein engineering and protein delivery. Nat Commun. 2017 Jun 06; 8:15790. PMID: 28585549.
        View in: PubMed
      4. Kim YB, Komor A, Levy JM, Packer MS, Zhao KT, Liu DR. Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions. Nat Biotechnol. 2017 Apr; 35(4):371-376. PMID: 28191901.
        View in: PubMed
      5. Komor A, Badran AH, Liu DR. CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes. Cell. 2017 Jan 12; 168(1-2):20-36. PMID: 27866654.
        View in: PubMed
      6. Komor A, Kim YB, Packer MS, Zuris JA, Liu DR. Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage. Nature. 2016 05 19; 533(7603):420-4. PMID: 27096365; PMCID: PMC4873371 [Available on 10/20/16].
      7. Komor A, Barton JK. An unusual ligand coordination gives rise to a new family of rhodium metalloinsertors with improved selectivity and potency. J Am Chem Soc. 2014 Oct 08; 136(40):14160-72. PMID: 25254630; PMCID: PMC4195389.
      8. Weidmann AG, Komor A, Barton JK. Targeted Chemotherapy with Metal Complexes. Comments Mod Chem A Comments Inorg Chem. 2014 May; 34(3-4):114-123. PMID: 25642012.
        View in: PubMed
      9. Bailis JM, Gordon ML, Gurgel JL, Komor A, Barton JK, Kirsch IR. An inducible, isogenic cancer cell line system for targeting the state of mismatch repair deficiency. PLoS One. 2013; 8(10):e78726. PMID: 24205301; PMCID: PMC3812133.
      10. Weidmann AG, Komor A, Barton JK. Biological effects of simple changes in functionality on rhodium metalloinsertors. Philos Trans A Math Phys Eng Sci. 2013 Jul 28; 371(1995):20120117. PMID: 23776288; PMCID: PMC3685451.
      11. Komor A, Barton JK. The path for metal complexes to a DNA target. Chem Commun (Camb). 2013 May 07; 49(35):3617-30. PMID: 23423158; PMCID: PMC3660861.
      12. Komor A, Schneider CJ, Weidmann AG, Barton JK. Cell-selective biological activity of rhodium metalloinsertors correlates with subcellular localization. J Am Chem Soc. 2012 Nov 21; 134(46):19223-33. PMID: 23137296; PMCID: PMC3740518.
      13. Ernst RJ, Komor A, Barton JK. Selective cytotoxicity of rhodium metalloinsertors in mismatch repair-deficient cells. Biochemistry. 2011 Dec 20; 50(50):10919-28. PMID: 22103240; PMCID: PMC3364161.
      14. Soo HS, Komor A, Iavarone AT, Chang CJ. A hydrogen-bond facilitated cycle for oxygen reduction by an acid- and base-compatible iron platform. Inorg Chem. 2009 Nov 02; 48(21):10024-35. PMID: 19780564.
        View in: PubMed