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Colleen McHugh

Title(s)Assistant Professor, Chemistry and Biochemistry
SchoolAcademic Aff
Address9500 Gilman Drive #0314
La Jolla CA 92093
Phone858-822-1995
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    Collapse Research 
    Collapse Research Activities and Funding
    Mechanisms of large non-coding RNA regulation of gene expression
    NIH/NIGMS R00GM120494Sep 1, 2016 - Dec 31, 2020
    Role: Principal Investigator
    Mechanisms of large non-coding RNA regulation of gene expression
    NIH/NIGMS K99GM120494Sep 1, 2016 - Dec 31, 2017
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. RAP-MS: A Method to Identify Proteins that Interact Directly with a Specific RNA Molecule in Cells. Methods Mol Biol. 2018; 1649:473-488. McHugh CA, Guttman M. PMID: 29130217.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    2. The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3. Nature. 2015 May 14; 521(7551):232-6. McHugh CA, Chen CK, Chow A, Surka CF, Tran C, McDonel P, Pandya-Jones A, Blanco M, Burghard C, Moradian A, Sweredoski MJ, Shishkin AA, Su J, Lander ES, Hess S, Plath K, Guttman M. PMID: 25915022.
      View in: PubMed   Mentions: 254     Fields:    Translation:AnimalsCells
    3. A virus capsid-like nanocompartment that stores iron and protects bacteria from oxidative stress. EMBO J. 2014 Sep 01; 33(17):1896-911. McHugh CA, Fontana J, Nemecek D, Cheng N, Aksyuk AA, Heymann JB, Winkler DC, Lam AS, Wall JS, Steven AC, Hoiczyk E. PMID: 25024436.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    4. Methods for comprehensive experimental identification of RNA-protein interactions. Genome Biol. 2014 Jan 27; 15(1):203. McHugh CA, Russell P, Guttman M. PMID: 24467948.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    5. BacM, an N-terminally processed bactofilin of Myxococcus xanthus, is crucial for proper cell shape. Mol Microbiol. 2011 May; 80(4):1031-51. Koch MK, McHugh CA, Hoiczyk E. PMID: 21414039.
      View in: PubMed   Mentions: 26     Fields:    Translation:Cells
    6. Lipid body formation plays a central role in cell fate determination during developmental differentiation of Myxococcus xanthus. Mol Microbiol. 2009 Oct; 74(2):497-517. Hoiczyk E, Ring MW, McHugh CA, Schwär G, Bode E, Krug D, Altmeyer MO, Lu JZ, Bode HB. PMID: 19788540.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    7. The Anopheles gambiae adult midgut peritrophic matrix proteome. Insect Biochem Mol Biol. 2009 Feb; 39(2):125-34. Dinglasan RR, Devenport M, Florens L, Johnson JR, McHugh CA, Donnelly-Doman M, Carucci DJ, Yates JR, Jacobs-Lorena M. PMID: 19038338.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    8. Fragment-based identification of determinants of conformational and spectroscopic change at the ricin active site. BMC Struct Biol. 2007 Nov 06; 7:72. Carra JH, McHugh CA, Mulligan S, Machiesky LM, Soares AS, Millard CB. PMID: 17986339.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    9. Improved stability of a protein vaccine through elimination of a partially unfolded state. Protein Sci. 2004 Oct; 13(10):2736-43. McHugh CA, Tammariello RF, Millard CB, Carra JH. PMID: 15340172.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells