Omar Akbari

Title(s)Professor, Cell and Developmental Biology
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
Emailoakbari@ucsd.edu
ORCID ORCID Icon0000-0002-6853-988 Additional info
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    Collapse Biography 
    Collapse Education and Training
    University of Nevada, Reno, RenoPh.D12/2008Cell and Molecular Biology
    University of Nevada, Reno, RenoBS/MS05/2005Biotechnology
    Caltech, PasadenaPostdoc07/2015Biological Engineering
    Collapse Awards and Honors
    National Academy of Engineering (NAE)2021 Gilbreth Lecturer
    DARPA2020DARPA ReVector Award
    NIH2019NIH Director's New Innovator Award
    University of Nevada, Reno.2018Mackay Young Alumni of the Year Award
    DARPA2017DARPA Safe Genes Award
    NIH2015NIH Career Transition Award

    Collapse Overview 
    Collapse Overview
    In May of 2005, Omar Akbari received a B.S./M.S. in Biotechnology from the University of Nevada, Reno. In December of 2008, he received a Ph.D. in Cell and Molecular Biology from the University of Nevada, Reno where he studied transcriptional regulation during development. He then joined the laboratory of professor Bruce A. Hay at the California Institute of Technology as a Postdoctoral Scholar to develop population control technologies for animals. In 2015, he became an Assistant Professor of Entomology in the Center for Infectious Disease Vector Research (CIDVR) at the University of California, Riverside. In fall of 2017, he joined the faculty as an Assistant Professor in the Cell and Developmental Biology Section, within the Division of Biological Sciences, at the University of California, San Diego. In 2018 he co-founded Agragene a biotechnology based startup in San Diego, CA. In 2019 he was promoted to Associate Professor (w/Tenure) in the Cell and Developmental Biology Section, within the Division of Biological Sciences at the University of California, San Diego.
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    Collapse Research 
    Collapse Research Activities and Funding
    The olfactory basis of locating nectar sugar sources in Aedes aegypti mosquitoes
    NIH R01AI148300Mar 5, 2021 - Feb 28, 2026
    Role: Co-Principal Investigator
    Development of precision genome editing tools in Ae. albopictus for functional genetics and mosquito control technologies
    NIH R21AI156078Mar 3, 2021 - Feb 28, 2023
    Role: Principal Investigator
    Precision guided SIT for the control of vector-borne disease
    NIH R01AI151004Jan 23, 2020 - Dec 31, 2024
    Role: Principal Investigator
    Transcriptome engineering technologies for the development of antiviral effectors in mosquitoes
    NIH R21AI149161Jan 23, 2020 - Dec 31, 2021
    Role: Principal Investigator
    Development of synthetic viral circuitry to regulate viruses in mosquito disease vectors
    NIH DP2AI152071Sep 30, 2019 - Mar 31, 2024
    Role: Principal Investigator
    Developing reciprocal chromosomal translocations for wild population replacement in an important vector of human disease.
    NIH R21AI123937Dec 19, 2016 - Nov 30, 2019
    Role: Principal Investigator
    Synthetically engineering population control systems in vectors of human disease
    NIH K22AI113060Aug 11, 2015 - Jul 31, 2018
    Role: Principal Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. CRISPR Diagnostics: Advances toward the Point of Care. Biochemistry. 2022 Mar 24. Brogan DJ, Akbari OS. PMID: 35325535.
      View in: PubMed   Mentions:    Fields:    
    2. California Residents' Perceptions of Gene Drive Systems to Control Mosquito-Borne Disease. Front Bioeng Biotechnol. 2022; 10:848707. Schairer CE, Triplett C, Akbari OS, Bloss CS. PMID: 35360388; PMCID: PMC8960626.
      View in: PubMed   Mentions:
    3. Author Correction: Transgenic refractory Aedes aegypti lines are resistant to multiple serotypes of dengue virus. Sci Rep. 2022 Jan 10; 12(1):754. Liu WL, Hsu CW, Chan SP, Yen PS, Su MP, Li JC, Li HH, Cheng L, Tang CK, Ko SH, Tsai HK, Tsai ZT, Akbari OS, Failloux AB, Chen CH. PMID: 35013523; PMCID: PMC8748990.
      View in: PubMed   Mentions:    Fields:    
    4. CRISPR-Mediated Genome Engineering in Aedes aegypti. Methods Mol Biol. 2022; 2509:23-51. Sun R, Li M, McMeniman CJ, Akbari OS. PMID: 35796955.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    5. Scale-type-specific requirement for the mosquito Aedes aegypti Spindle-F homologue by regulating microtubule organization. Insect Mol Biol. 2022 04; 31(2):216-224. Djokic S, Bakhrat A, Li M, Akbari OS, Abdu U. PMID: 34919304.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCellsPHPublic Health
    6. Transgenic refractory Aedes aegypti lines are resistant to multiple serotypes of dengue virus. Sci Rep. 2021 12 13; 11(1):23865. Liu WL, Hsu CW, Chan SP, Yen PS, Su MP, Li JC, Li HH, Cheng L, Tang CK, Ko SH, Tsai HK, Tsai ZT, Akbari OS, Failloux AB, Chen CH. PMID: 34903766; PMCID: PMC8668939.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCellsPHPublic Health
    7. Exploiting a Y chromosome-linked Cas9 for sex selection and gene drive. Nat Commun. 2021 12 10; 12(1):7202. Gamez S, Chaverra-Rodriguez D, Buchman A, Kandul NP, Mendez-Sanchez SC, Bennett JB, Sánchez C HM, Yang T, Antoshechkin I, Duque JE, Papathanos PA, Marshall JM, Akbari OS. PMID: 34893590; PMCID: PMC8664916.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    8. Temperature-Inducible Precision-Guided Sterile Insect Technique. CRISPR J. 2021 12; 4(6):822-835. Kandul NP, Liu J, Akbari OS. PMID: 34735288; PMCID: PMC8742271.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    9. Development of a Rapid and Sensitive CasRx-Based Diagnostic Assay for SARS-CoV-2. ACS Sens. 2021 11 26; 6(11):3957-3966. Brogan DJ, Chaverra-Rodriguez D, Lin CP, Smidler AL, Yang T, Alcantara LM, Antoshechkin I, Liu J, Raban RR, Belda-Ferre P, Knight R, Komives EA, Akbari OS. PMID: 34714054; PMCID: PMC8577378.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    10. Parasitic nematode fatty acid- and retinol-binding proteins compromise host immunity by interfering with host lipid signaling pathways. PLoS Pathog. 2021 10; 17(10):e1010027. Parks SC, Nguyen S, Nasrolahi S, Bhat C, Juncaj D, Lu D, Ramaswamy R, Dhillon H, Fujiwara H, Buchman A, Akbari OS, Yamanaka N, Boulanger MJ, Dillman AR. PMID: 34714893; PMCID: PMC8580252.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    11. Human attractive cues and mosquito host-seeking behavior. Trends Parasitol. 2022 03; 38(3):246-264. Coutinho-Abreu IV, Riffell JA, Akbari OS. PMID: 34674963.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    12. Genetically Encoded CRISPR Components Yield Efficient Gene Editing in the Invasive Pest Drosophila suzukii. CRISPR J. 2021 10; 4(5):739-751. Kandul NP, Belikoff EJ, Liu J, Buchman A, Li F, Yamamoto A, Yang T, Shriner I, Scott MJ, Akbari OS. PMID: 34661429.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsPHPublic Health
    13. Suppressing mosquito populations with precision guided sterile males. Nat Commun. 2021 09 10; 12(1):5374. Li M, Yang T, Bui M, Gamez S, Wise T, Kandul NP, Liu J, Alcantara L, Lee H, Edula JR, Raban R, Zhan Y, Wang Y, DeBeaubien N, Chen J, Sánchez C HM, Bennett JB, Antoshechkin I, Montell C, Marshall JM, Akbari OS. PMID: 34508072; PMCID: PMC8433431.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    14. Oxitec and MosquitoMate in the United States: lessons for the future of gene drive mosquito control. Pathog Glob Health. 2021 09; 115(6):365-376. Schairer CE, Najera J, James AA, Akbari OS, Bloss CS. PMID: 34313556; PMCID: PMC8592615.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCellsPHPublic Health
    15. Combating mosquito-borne diseases using genetic control technologies. Nat Commun. 2021 07 19; 12(1):4388. Wang GH, Gamez S, Raban RR, Marshall JM, Alphey L, Li M, Rasgon JL, Akbari OS. PMID: 34282149; PMCID: PMC8290041.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    16. Author Correction: Improved reference genome of the arboviral vector Aedes albopictus. Genome Biol. 2021 Jul 12; 22(1):205. Palatini U, Masri RA, Cosme LV, Koren S, Thibaud-Nissen F, Biedler JK, Krsticevic F, Johnston JS, Halbach R, Crawford JE, Antoshechkin I, Failloux AB, Pischedda E, Marconcini M, Ghurye J, Rhie A, Sharma A, Karagodin DA, Jenrette J, Gamez S, Miesen P, Masterson P, Caccone A, Sharakhova MV, Tu Z, Papathanos PA, Van Rij RP, Akbari OS, Powell J, Phillippy AM, Bonizzoni M. PMID: 34253230; PMCID: PMC8274027.
      View in: PubMed   Mentions:    Fields:    
    17. Engineered reproductively isolated species drive reversible population replacement. Nat Commun. 2021 06 02; 12(1):3281. Buchman A, Shriner I, Yang T, Liu J, Antoshechkin I, Marshall JM, Perry MW, Akbari OS. PMID: 34078888; PMCID: PMC8173020.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    18. Suppression of female fertility in Aedes aegypti with a CRISPR-targeted male-sterile mutation. Proc Natl Acad Sci U S A. 2021 06 01; 118(22). Chen J, Luo J, Wang Y, Gurav AS, Li M, Akbari OS, Montell C. PMID: 34031258; PMCID: PMC8179229.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsPHPublic Health
    19. Spatial control of gene expression in flies using bacterially derived binary transactivation systems. Insect Mol Biol. 2021 10; 30(5):461-471. Gamez S, Vesga LC, Mendez-Sanchez SC, Akbari OS. PMID: 33963794; PMCID: PMC8459377.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    20. Inherently confinable split-drive systems in Drosophila. Nat Commun. 2021 03 05; 12(1):1480. Terradas G, Buchman AB, Bennett JB, Shriner I, Marshall JM, Akbari OS, Bier E. PMID: 33674604; PMCID: PMC7935863.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    21. A confinable home-and-rescue gene drive for population modification. Elife. 2021 03 05; 10. Kandul NP, Liu J, Bennett JB, Marshall JM, Akbari OS. PMID: 33666174; PMCID: PMC7968924.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    22. Mechanistically comparing reproductive manipulations caused by selfish chromosomes and bacterial symbionts. Heredity (Edinb). 2021 05; 126(5):707-716. Dalla Benetta E, Akbari OS, Ferree PM. PMID: 33649572; PMCID: PMC8102561.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    23. Ubiquitous and Tissue-specific RNA Targeting in Drosophila Melanogaster using CRISPR/CasRx. J Vis Exp. 2021 02 05; (168). Sun R, Brogan D, Buchman A, Yang T, Akbari OS. PMID: 33616113.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    24. A mosquito small RNA genomics resource reveals dynamic evolution and host responses to viruses and transposons. Genome Res. 2021 03; 31(3):512-528. Ma Q, Srivastav SP, Gamez S, Dayama G, Feitosa-Suntheimer F, Patterson EI, Johnson RM, Matson EM, Gold AS, Brackney DE, Connor JH, Colpitts TM, Hughes GL, Rasgon JL, Nolan T, Akbari OS, Lau NC. PMID: 33419731; PMCID: PMC7919454.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    25. Core commitments for field trials of gene drive organisms. Science. 2020 12 18; 370(6523):1417-1419. Long KC, Alphey L, Annas GJ, Bloss CS, Campbell KJ, Champer J, Chen CH, Choudhary A, Church GM, Collins JP, Cooper KL, Delborne JA, Edwards OR, Emerson CI, Esvelt K, Evans SW, Friedman RM, Gantz VM, Gould F, Hartley S, Heitman E, Hemingway J, Kanuka H, Kuzma J, Lavery JV, Lee Y, Lorenzen M, Lunshof JE, Marshall JM, Messer PW, Montell C, Oye KA, Palmer MJ, Papathanos PA, Paradkar PN, Piaggio AJ, Rasgon JL, Rašic G, Rudenko L, Saah JR, Scott MJ, Sutton JT, Vorsino AE, Akbari OS. PMID: 33335055.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    26. Pupal and Adult Injections for RNAi and CRISPR Gene Editing in Nasonia vitripennis. J Vis Exp. 2020 12 04; (166). Dalla Benetta E, Chaverra-Rodriguez D, Rasgon JL, Akbari OS. PMID: 33346197.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    27. Targeting female flight for genetic control of mosquitoes. PLoS Negl Trop Dis. 2020 12; 14(12):e0008876. Navarro-Payá D, Flis I, Anderson MAE, Hawes P, Li M, Akbari OS, Basu S, Alphey L. PMID: 33270627; PMCID: PMC7714197.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsPHPublic Health
    28. Opinion: Standardizing the definition of gene drive. Proc Natl Acad Sci U S A. 2020 12 08; 117(49):30864-30867. Alphey LS, Crisanti A, Randazzo FF, Akbari OS. PMID: 33208534; PMCID: PMC7733814.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    29. Interdisciplinary development of a standardized introduction to gene drives for lay audiences. BMC Med Res Methodol. 2020 11 05; 20(1):273. Schairer CE, Triplett C, Buchman A, Akbari OS, Bloss CS. PMID: 33153449; PMCID: PMC7643426.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    30. A Sensitive, Rapid, and Portable CasRx-based Diagnostic Assay for SARS-CoV-2. medRxiv. 2020 Oct 20. Brogan DJ, Chaverra-Rodriguez D, Lin CP, Smidler AL, Yang T, Alcantara LM, Antoshechkin I, Liu J, Raban RR, Belda-Ferre P, Knight R, Komives EA, Akbari OS. PMID: 33106816; PMCID: PMC7587836.
      View in: PubMed   Mentions:
    31. Diverse Defenses: A Perspective Comparing Dipteran Piwi-piRNA Pathways. Cells. 2020 09 27; 9(10). Gamez S, Srivastav S, Akbari OS, Lau NC. PMID: 32992598; PMCID: PMC7601171.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    32. Active Genetic Neutralizing Elements for Halting or Deleting Gene Drives. Mol Cell. 2020 10 15; 80(2):246-262.e4. Xu XS, Bulger EA, Gantz VM, Klanseck C, Heimler SR, Auradkar A, Bennett JB, Miller LA, Leahy S, Juste SS, Buchman A, Akbari OS, Marshall JM, Bier E. PMID: 32949493.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    33. A day in the life of a mosquito insectary team: pushing for solutions to mosquito-borne diseases. Lab Anim (NY). 2020 09; 49(9):241-243. Raban RR, Akbari OS. PMID: 32807984.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    34. Improved reference genome of the arboviral vector Aedes albopictus. Genome Biol. 2020 08 26; 21(1):215. Palatini U, Masri RA, Cosme LV, Koren S, Thibaud-Nissen F, Biedler JK, Krsticevic F, Johnston JS, Halbach R, Crawford JE, Antoshechkin I, Failloux AB, Pischedda E, Marconcini M, Ghurye J, Rhie A, Sharma A, Karagodin DA, Jenrette J, Gamez S, Miesen P, Masterson P, Caccone A, Sharakhova MV, Tu Z, Papathanos PA, Van Rij RP, Akbari OS, Powell J, Phillippy AM, Bonizzoni M. PMID: 32847630; PMCID: PMC7448346.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCellsPHPublic Health
    35. Germline mutagenesis of Nasonia vitripennis through ovarian delivery of CRISPR-Cas9 ribonucleoprotein. Insect Mol Biol. 2020 12; 29(6):569-577. Chaverra-Rodriguez D, Dalla Benetta E, Heu CC, Rasgon JL, Ferree PM, Akbari OS. PMID: 32715554.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    36. Translating gene drive science to promote linguistic diversity in community and stakeholder engagement. Glob Public Health. 2020 10; 15(10):1551-1565. Cheung C, Gamez S, Carballar-Lejarazú R, Ferman V, Vásquez VN, Terradas G, Ishikawa J, Schairer CE, Bier E, Marshall JM, James AA, Akbari OS, Bloss CS. PMID: 32589115.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsPHPublic Health
    37. Programmable RNA Targeting Using CasRx in Flies. CRISPR J. 2020 06; 3(3):164-176. Buchman AB, Brogan DJ, Sun R, Yang T, Hsu PD, Akbari OS. PMID: 32584145; PMCID: PMC7307691.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    38. Embryo Microinjection Techniques for Efficient Site-Specific Mutagenesis in Culex quinquefasciatus. J Vis Exp. 2020 05 24; (159). Bui M, Li M, Raban RR, Liu N, Akbari OS. PMID: 32510506.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCellsPHPublic Health
    39. Modeling confinement and reversibility of threshold-dependent gene drive systems in spatially-explicit Aedes aegypti populations. BMC Biol. 2020 05 12; 18(1):50. Sánchez C HM, Bennett JB, Wu SL, Rašic G, Akbari OS, Marshall JM. PMID: 32398005; PMCID: PMC7218562.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsPHPublic Health
    40. A drug-inducible sex-separation technique for insects. Nat Commun. 2020 04 30; 11(1):2106. Kandul NP, Liu J, Hsu AD, Hay BA, Akbari OS. PMID: 32355156; PMCID: PMC7193620.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCellsPHPublic Health
    41. Correction: Broad dengue neutralization in mosquitoes expressing an engineered antibody. PLoS Pathog. 2020 04; 16(4):e1008545. Buchman A, Gamez S, Li M, Antoshechkin I, Li HH, Wang HW, Chen CH, Klein MJ, Duchemin JB, Crowe JE, Paradkar PN, Akbari OS. PMID: 32348355; PMCID: PMC7190102.
      View in: PubMed   Mentions:    Fields:    
    42. Genome elimination mediated by gene expression from a selfish chromosome. Sci Adv. 2020 04; 6(14):eaaz9808. Dalla Benetta E, Antoshechkin I, Yang T, Nguyen HQM, Ferree PM, Akbari OS. PMID: 32284986; PMCID: PMC7124933.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    43. The Developmental Transcriptome of Aedes albopictus, a Major Worldwide Human Disease Vector. G3 (Bethesda). 2020 03 05; 10(3):1051-1062. Gamez S, Antoshechkin I, Mendez-Sanchez SC, Akbari OS. PMID: 31964684; PMCID: PMC7056973.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    44. Progress towards engineering gene drives for population control. J Exp Biol. 2020 02 07; 223(Pt Suppl 1). Raban RR, Marshall JM, Akbari OS. PMID: 32034041; PMCID: PMC7790193.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    45. Assessment of a Split Homing Based Gene Drive for Efficient Knockout of Multiple Genes. G3 (Bethesda). 2020 02 06; 10(2):827-837. Kandul NP, Liu J, Buchman A, Gantz VM, Bier E, Akbari OS. PMID: 31882406; PMCID: PMC7003086.
      View in: PubMed   Mentions: 25     Fields:    Translation:Cells
    46. Development of a confinable gene drive system in the human disease vector Aedes aegypti. Elife. 2020 01 21; 9. Li M, Yang T, Kandul NP, Bui M, Gamez S, Raban R, Bennett J, Sánchez C HM, Lanzaro GC, Schmidt H, Lee Y, Marshall JM, Akbari OS. PMID: 31960794; PMCID: PMC6974361.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsPHPublic Health
    47. Broad dengue neutralization in mosquitoes expressing an engineered antibody. PLoS Pathog. 2020 01; 16(1):e1008103. Buchman A, Gamez S, Li M, Antoshechkin I, Li HH, Wang HW, Chen CH, Klein MJ, Duchemin JB, Crowe JE, Paradkar PN, Akbari OS. PMID: 31945137; PMCID: PMC6964813.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    48. The olfactory basis of orchid pollination by mosquitoes. Proc Natl Acad Sci U S A. 2020 01 07; 117(1):708-716. Lahondère C, Vinauger C, Okubo RP, Wolff GH, Chan JK, Akbari OS, Riffell JA. PMID: 31871198; PMCID: PMC6955360.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCellsPHPublic Health
    49. Methods for the generation of heritable germline mutations in the disease vector Culex quinquefasciatus using clustered regularly interspaced short palindrome repeats-associated protein 9. Insect Mol Biol. 2020 04; 29(2):214-220. Li M, Li T, Liu N, Raban RR, Wang X, Akbari OS. PMID: 31693260.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsPHPublic Health
    50. A typology of community and stakeholder engagement based on documented examples in the field of novel vector control. PLoS Negl Trop Dis. 2019 11; 13(11):e0007863. Schairer CE, Taitingfong R, Akbari OS, Bloss CS. PMID: 31765377; PMCID: PMC6901234.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansPHPublic Health
    51. Winning the Tug-of-War Between Effector Gene Design and Pathogen Evolution in Vector Population Replacement Strategies. Front Genet. 2019; 10:1072. Marshall JM, Raban RR, Kandul NP, Edula JR, León TM, Akbari OS. PMID: 31737050; PMCID: PMC6831721.
      View in: PubMed   Mentions: 14  
    52. Malaria eradication within a generation: ambitious, achievable, and necessary. Lancet. 2019 09 21; 394(10203):1056-1112. Feachem RGA, Chen I, Akbari O, Bertozzi-Villa A, Bhatt S, Binka F, Boni MF, Buckee C, Dieleman J, Dondorp A, Eapen A, Sekhri Feachem N, Filler S, Gething P, Gosling R, Haakenstad A, Harvard K, Hatefi A, Jamison D, Jones KE, Karema C, Kamwi RN, Lal A, Larson E, Lees M, Lobo NF, Micah AE, Moonen B, Newby G, Ning X, Pate M, Quiñones M, Roh M, Rolfe B, Shanks D, Singh B, Staley K, Tulloch J, Wegbreit J, Woo HJ, Mpanju-Shumbusho W. PMID: 31511196.
      View in: PubMed   Mentions: 95     Fields:    Translation:HumansPHPublic Health
    53. Reply to 'Concerns about the feasibility of using "precision guided sterile males" to control insects'. Nat Commun. 2019 09 02; 10(1):3955. Kandul NP, Liu J, Sanchez C HM, Wu SL, Marshall JM, Akbari OS. PMID: 31477702; PMCID: PMC6718384.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    54. Visual-Olfactory Integration in the Human Disease Vector Mosquito Aedes aegypti. Curr Biol. 2019 08 05; 29(15):2509-2516.e5. Vinauger C, Van Breugel F, Locke LT, Tobin KKS, Dickinson MH, Fairhall AL, Akbari OS, Riffell JA. PMID: 31327719; PMCID: PMC6771019.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCellsPHPublic Health
    55. Live calcium imaging of Aedes aegypti neuronal tissues reveals differential importance of chemosensory systems for life-history-specific foraging strategies. BMC Neurosci. 2019 06 17; 20(1):27. Bui M, Shyong J, Lutz EK, Yang T, Li M, Truong K, Arvidson R, Buchman A, Riffell JA, Akbari OS. PMID: 31208328; PMCID: PMC6580577.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    56. Sequence Expression of Supernumerary B Chromosomes: Function or Fluff? Genes (Basel). 2019 02 08; 10(2). Dalla Benetta E, Akbari OS, Ferree PM. PMID: 30744010; PMCID: PMC6409846.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    57. Engineered resistance to Zika virus in transgenic Aedes aegypti expressing a polycistronic cluster of synthetic small RNAs. Proc Natl Acad Sci U S A. 2019 02 26; 116(9):3656-3661. Buchman A, Gamez S, Li M, Antoshechkin I, Li HH, Wang HW, Chen CH, Klein MJ, Duchemin JB, Paradkar PN, Akbari OS. PMID: 30723148; PMCID: PMC6397566.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    58. Transforming insect population control with precision guided sterile males with demonstration in flies. Nat Commun. 2019 01 08; 10(1):84. Kandul NP, Liu J, Sanchez C HM, Wu SL, Marshall JM, Akbari OS. PMID: 30622266; PMCID: PMC6325135.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsPHPublic Health
    59. Improved reference genome of Aedes aegypti informs arbovirus vector control. Nature. 2018 11; 563(7732):501-507. Matthews BJ, Dudchenko O, Kingan SB, Koren S, Antoshechkin I, Crawford JE, Glassford WJ, Herre M, Redmond SN, Rose NH, Weedall GD, Wu Y, Batra SS, Brito-Sierra CA, Buckingham SD, Campbell CL, Chan S, Cox E, Evans BR, Fansiri T, Filipovic I, Fontaine A, Gloria-Soria A, Hall R, Joardar VS, Jones AK, Kay RGG, Kodali VK, Lee J, Lycett GJ, Mitchell SN, Muehling J, Murphy MR, Omer AD, Partridge FA, Peluso P, Aiden AP, Ramasamy V, Rašic G, Roy S, Saavedra-Rodriguez K, Sharan S, Sharma A, Smith ML, Turner J, Weakley AM, Zhao Z, Akbari OS, Black WC, Cao H, Darby AC, Hill CA, Johnston JS, Murphy TD, Raikhel AS, Sattelle DB, Sharakhov IV, White BJ, Zhao L, Aiden EL, Mann RS, Lambrechts L, Powell JR, Sharakhova MV, Tu Z, Robertson HM, McBride CS, Hastie AR, Korlach J, Neafsey DE, Phillippy AM, Vosshall LB. PMID: 30429615; PMCID: PMC6421076.
      View in: PubMed   Mentions: 142     Fields:    Translation:AnimalsCellsPHPublic Health
    60. Site-specific transgenesis of the Drosophila melanogaster Y-chromosome using CRISPR/Cas9. Insect Mol Biol. 2019 02; 28(1):65-73. Buchman A, Akbari OS. PMID: 30079589; PMCID: PMC8459378.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    61. Gene editing technologies and applications for insects. Curr Opin Insect Sci. 2018 08; 28:66-72. Gantz VM, Akbari OS. PMID: 30551769; PMCID: PMC6296244.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    62. Synthetically engineered Medea gene drive system in the worldwide crop pest Drosophila suzukii. Proc Natl Acad Sci U S A. 2018 05 01; 115(18):4725-4730. Buchman A, Marshall JM, Ostrovski D, Yang T, Akbari OS. PMID: 29666236; PMCID: PMC5939061.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsPHPublic Health
    63. Engineered Reciprocal Chromosome Translocations Drive High Threshold, Reversible Population Replacement in Drosophila. ACS Synth Biol. 2018 05 18; 7(5):1359-1370. Buchman AB, Ivy T, Marshall JM, Akbari OS, Hay BA. PMID: 29608276.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    64. Gene drives may be the next step towards sustainable control of malaria. Pathog Glob Health. 2017 12; 111(8):399-400. Raban R, Akbari OS. PMID: 29566584; PMCID: PMC6066854.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansPHPublic Health
    65. Can CRISPR-Based Gene Drive Be Confined in the Wild? A Question for Molecular and Population Biology. ACS Chem Biol. 2018 02 16; 13(2):424-430. Marshall JM, Akbari OS. PMID: 29370514.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    66. Modulation of Host Learning in Aedes aegypti Mosquitoes. Curr Biol. 2018 02 05; 28(3):333-344.e8. Vinauger C, Lahondère C, Wolff GH, Locke LT, Liaw JE, Parrish JZ, Akbari OS, Dickinson MH, Riffell JA. PMID: 29395917; PMCID: PMC6771430.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimals
    67. Highly Efficient Site-Specific Mutagenesis in Malaria Mosquitoes Using CRISPR. G3 (Bethesda). 2018 02 02; 8(2):653-658. Li M, Akbari OS, White BJ. PMID: 29233915; PMCID: PMC5919725.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsPHPublic Health
    68. Embryo Microinjection and Transplantation Technique for Nasonia vitripennis Genome Manipulation. J Vis Exp. 2017 12 25; (130). Li M, Bui M, Akbari OS. PMID: 29364231; PMCID: PMC5908372.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    69. Erratum to: Unique sequence organization and small RNA expression of a "selfish" B chromosome. Chromosoma. 2017 12; 126(6):781. Li Y, Jing XA, Aldrich JC, Clifford C, Chen J, Akbari OS, Ferree PM. PMID: 28821911.
      View in: PubMed   Mentions:    Fields:    
    70. Germline Cas9 expression yields highly efficient genome engineering in a major worldwide disease vector, Aedes aegypti. Proc Natl Acad Sci U S A. 2017 12 05; 114(49):E10540-E10549. Li M, Bui M, Yang T, Bowman CS, White BJ, Akbari OS. PMID: 29138316; PMCID: PMC5724270.
      View in: PubMed   Mentions: 57     Fields:    Translation:AnimalsCellsPHPublic Health
    71. Rules of the road for insect gene drive research and testing. Nat Biotechnol. 2017 08 08; 35(8):716-718. Adelman Z, Akbari O, Bauer J, Bier E, Bloss C, Carter SR, Callender C, Denis AC, Cowhey P, Dass B, Delborne J, Devereaux M, Ellsworth P, Friedman RM, Gantz V, Gibson C, Hay BA, Hoddle M, James AA, James S, Jorgenson L, Kalichman M, Marshall J, McGinnis W, Newman J, Pearson A, Quemada H, Rudenko L, Shelton A, Vinetz JM, Weisman J, Wong B, Wozniak C. PMID: 28787415; PMCID: PMC5831321.
      View in: PubMed   Mentions: 32     Fields:    
    72. Unique sequence organization and small RNA expression of a "selfish" B chromosome. Chromosoma. 2017 Dec; 126(6):753-768. Li Y, Jing XA, Aldrich JC, Clifford C, Chen J, Akbari OS, Ferree PM. PMID: 28780664.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    73. Overcoming evolved resistance to population-suppressing homing-based gene drives. Sci Rep. 2017 06 19; 7(1):3776. Marshall JM, Buchman A, Sánchez C HM, Akbari OS. PMID: 28630470; PMCID: PMC5476637.
      View in: PubMed   Mentions: 64     Fields:    Translation:Animals
    74. Generation of heritable germline mutations in the jewel wasp Nasonia vitripennis using CRISPR/Cas9. Sci Rep. 2017 04 19; 7(1):901. Li M, Au LYC, Douglah D, Chong A, White BJ, Ferree PM, Akbari OS. PMID: 28424460; PMCID: PMC5430486.
      View in: PubMed   Mentions: 26     Fields:    Translation:Animals
    75. Mapping a multiplexed zoo of mRNA expression. Development. 2016 10 01; 143(19):3632-3637. Choi HM, Calvert CR, Husain N, Huss D, Barsi JC, Deverman BE, Hunter RC, Kato M, Lee SM, Abelin AC, Rosenthal AZ, Akbari OS, Li Y, Hay BA, Sternberg PW, Patterson PH, Davidson EH, Mazmanian SK, Prober DA, van de Rijn M, Leadbetter JR, Newman DK, Readhead C, Bronner ME, Wold B, Lansford R, Sauka-Spengler T, Fraser SE, Pierce NA. PMID: 27702788; PMCID: PMC5087610.
      View in: PubMed   Mentions: 67     Fields:    Translation:HumansAnimals
    76. Male-Killing Spiroplasma Alters Behavior of the Dosage Compensation Complex during Drosophila melanogaster Embryogenesis. Curr Biol. 2016 05 23; 26(10):1339-45. Cheng B, Kuppanda N, Aldrich JC, Akbari OS, Ferree PM. PMID: 27161498; PMCID: PMC4879104.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    77. Radical remodeling of the Y chromosome in a recent radiation of malaria mosquitoes. Proc Natl Acad Sci U S A. 2016 Apr 12; 113(15):E2114-23. Hall AB, Papathanos PA, Sharma A, Cheng C, Akbari OS, Assour L, Bergman NH, Cagnetti A, Crisanti A, Dottorini T, Fiorentini E, Galizi R, Hnath J, Jiang X, Koren S, Nolan T, Radune D, Sharakhova MV, Steele A, Timoshevskiy VA, Windbichler N, Zhang S, Hahn MW, Phillippy AM, Emrich SJ, Sharakhov IV, Tu ZJ, Besansky NJ. PMID: 27035980; PMCID: PMC4839409.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCellsPHPublic Health
    78. Cheating evolution: engineering gene drives to manipulate the fate of wild populations. Nat Rev Genet. 2016 Mar; 17(3):146-59. Champer J, Buchman A, Akbari OS. PMID: 26875679.
      View in: PubMed   Mentions: 137     Fields:    Translation:AnimalsCells
    79. Identification of Genes Uniquely Expressed in the Germ-Line Tissues of the Jewel Wasp Nasonia vitripennis. G3 (Bethesda). 2015 Oct 13; 5(12):2647-53. Ferree PM, Fang C, Mastrodimos M, Hay BA, Amrhein H, Akbari OS. PMID: 26464360; PMCID: PMC4683638.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    80. Vectored antibody gene delivery mediates long-term contraception. Curr Biol. 2015 Oct 05; 25(19):R820-2. Li J, Olvera AI, Akbari OS, Moradian A, Sweredoski MJ, Hess S, Hay BA. PMID: 26439332.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    81. BIOSAFETY. Safeguarding gene drive experiments in the laboratory. Science. 2015 Aug 28; 349(6251):927-9. Akbari OS, Bellen HJ, Bier E, Bullock SL, Burt A, Church GM, Cook KR, Duchek P, Edwards OR, Esvelt KM, Gantz VM, Golic KG, Gratz SJ, Harrison MM, Hayes KR, James AA, Kaufman TC, Knoblich J, Malik HS, Matthews KA, O'Connor-Giles KM, Parks AL, Perrimon N, Port F, Russell S, Ueda R, Wildonger J. PMID: 26229113; PMCID: PMC4692367.
      View in: PubMed   Mentions: 108     Fields:    Translation:AnimalsCells
    82. Identification of germline transcriptional regulatory elements in Aedes aegypti. Sci Rep. 2014 Feb 04; 4:3954. Akbari OS, Papathanos PA, Sandler JE, Kennedy K, Hay BA. PMID: 24492376; PMCID: PMC3912481.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCellsPHPublic Health
    83. The developmental transcriptome of the mosquito Aedes aegypti, an invasive species and major arbovirus vector. G3 (Bethesda). 2013 Sep 04; 3(9):1493-509. Akbari OS, Antoshechkin I, Amrhein H, Williams B, Diloreto R, Sandler J, Hay BA. PMID: 23833213; PMCID: PMC3755910.
      View in: PubMed   Mentions: 100     Fields:    Translation:AnimalsCellsPHPublic Health
    84. Transcriptome profiling of Nasonia vitripennis testis reveals novel transcripts expressed from the selfish B chromosome, paternal sex ratio. G3 (Bethesda). 2013 Sep 04; 3(9):1597-605. Akbari OS, Antoshechkin I, Hay BA, Ferree PM. PMID: 23893741; PMCID: PMC3755920.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    85. A synthetic gene drive system for local, reversible modification and suppression of insect populations. Curr Biol. 2013 Apr 22; 23(8):671-7. Akbari OS, Matzen KD, Marshall JM, Huang H, Ward CM, Hay BA. PMID: 23541732; PMCID: PMC8459379.
      View in: PubMed   Mentions: 65     Fields:    Translation:AnimalsCells
    86. Novel synthetic Medea selfish genetic elements drive population replacement in Drosophila; a theoretical exploration of Medea-dependent population suppression. ACS Synth Biol. 2014 Dec 19; 3(12):915-28. Akbari OS, Chen CH, Marshall JM, Huang H, Antoshechkin I, Hay BA. PMID: 23654248; PMCID: PMC3742681.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    87. Disruption of the abdominal-B promoter tethering element results in a loss of long-range enhancer-directed Hox gene expression in Drosophila. PLoS One. 2011 Jan 21; 6(1):e16283. Ho MC, Schiller BJ, Akbari OS, Bae E, Drewell RA. PMID: 21283702; PMCID: PMC3025016.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    88. The chromosomal association/dissociation of the chromatin insulator protein Cp190 of Drosophila melanogaster is mediated by the BTB/POZ domain and two acidic regions. BMC Cell Biol. 2010 Dec 31; 11:101. Oliver D, Sheehan B, South H, Akbari O, Pai CY. PMID: 21194420; PMCID: PMC3022720.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    89. An Entry/Gateway cloning system for general expression of genes with molecular tags in Drosophila melanogaster. BMC Cell Biol. 2009 Jan 29; 10:8. Akbari OS, Oliver D, Eyer K, Pai CY. PMID: 19178707; PMCID: PMC2654426.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    90. A novel promoter-tethering element regulates enhancer-driven gene expression at the bithorax complex in the Drosophila embryo. Development. 2008 Jan; 135(1):123-31. Akbari OS, Bae E, Johnsen H, Villaluz A, Wong D, Drewell RA. PMID: 18045839; PMCID: PMC2205987.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    91. The abdominal-B promoter tethering element mediates promoter-enhancer specificity at the Drosophila bithorax complex. Fly (Austin). 2007 Nov-Dec; 1(6):337-9. Akbari OS, Schiller BJ, Goetz SE, Ho MC, Bae E, Drewell RA. PMID: 18504507; PMCID: PMC2394718.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    92. Unraveling cis-regulatory mechanisms at the abdominal-A and Abdominal-B genes in the Drosophila bithorax complex. Dev Biol. 2006 May 15; 293(2):294-304. Akbari OS, Bousum A, Bae E, Drewell RA. PMID: 16545794.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
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